128(top 100%)
papers
16.9K(top 1%)
citations
62(top 100%)
h-index
132(top 100%)
g-index
178
all documents
18.4K
doc citations
1.9K
citing journals
100
times ranked

Publications

150 papers • 18,359 citations • Sorted by year • Download PDF (PDF by citations)
Sort: Year | Citations
#ArticleIFCitationsLinks
1Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
ELife, 2024, 12,
1.61Citations (PDF)
2A lineage-specific protein network at the trypanosome nuclear envelope
Nucleus, 2024, 15,
4.53Citations (PDF)
3Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA6.42Citations (PDF)
4A nucleotide binding–independent role for γ-tubulin in microtubule capping and cell division4.87Citations (PDF)
5Structural basis for substrate selection by the SARS-CoV-2 replicase
Nature, 2023, 614, 781-787
40.132Citations (PDF)
6A general method for quantitative fractionation of mammalian cells4.81Citations (PDF)
7Ultrasensitive Detection of Circulating LINE-1 ORF1p as a Specific Multicancer Biomarker
Cancer Discovery, 2023, 13, 2532-2547
26.423Citations (PDF)
8Author Response: Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
2023, ,
0Citations (PDF)
9Comprehensive structure and functional adaptations of the yeast nuclear pore complex
Cell, 2022, 185, 361-378.e25
35.197Citations (PDF)
10Author response: The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates
2022, ,
0Citations (PDF)
11Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease2.36Citations (PDF)
12Author response: Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
2022, ,
0Citations (PDF)
13Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA14.18Citations (PDF)
14Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM
Structure, 2021, 29, 186-195.e6
3.919Citations (PDF)
15Dissecting the Structural Dynamics of the Nuclear Pore Complex
Molecular Cell, 2021, 81, 153-165.e7
14.233Citations (PDF)
16Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function4.822Citations (PDF)
17Dynamic regulation of TFH selection during the germinal centre reaction
Nature, 2021, 591, 458-463
40.165Citations (PDF)
18Structural basis for backtracking by the SARS-CoV-2 replication–transcription complex7.776Citations (PDF)
19Author response: Analysis of the mechanosensor channel functionality of TACAN
2021, ,
0Citations (PDF)
20Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis
Cell, 2021, 184, 4579-4592.e24
35.1146Citations (PDF)
21Measuring in vivo protein turnover and exchange in yeast macromolecular assemblies
STAR Protocols, 2021, 2, 100800
1.14Citations (PDF)
22Author response: Structural basis for transcription complex disruption by the Mfd translocase
2021, ,
0Citations (PDF)
23A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies
Nucleic Acids Research, 2021, 49, 5407-5425
16.223Citations (PDF)
24Author response: Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
2021, ,
0Citations (PDF)
25Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex
Cell, 2020, 180, 165-175.e16
35.194Citations (PDF)
26Long-range intramolecular allostery and regulation in the dynein-like AAA protein Mdn17.76Citations (PDF)
27Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex
Cell, 2020, 182, 1560-1573.e13
35.1315Citations (PDF)
28Affinity proteomic dissection of the human nuclear cap-binding complex interactome
Nucleic Acids Research, 2020, 48, 10456-10469
16.218Citations (PDF)
29Stepwise Promoter Melting by Bacterial RNA Polymerase
Molecular Cell, 2020, 78, 275-288.e6
14.278Citations (PDF)
30Integrative structure and function of the yeast exocyst complex
Protein Science, 2020, 29, 1486-1501
5.920Citations (PDF)
31National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions
Journal of Proteome Research, 2020, 19, 1900-1912
3.77Citations (PDF)
32Native Mass Spectrometry Analysis of Affinity-Captured Endogenous Yeast RNA Exosome Complexes0.017Citations (PDF)
33Embryonic and Fetal Human Hemoglobins: Structures, Oxygen Binding, and Physiological Roles
Sub-Cellular Biochemistry, 2020, , 275-296
0.012Citations (PDF)
34Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality4.816Citations (PDF)
35Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations
PLoS ONE, 2019, 14, e0217897
2.57Citations (PDF)
36Palaeoproteomics resolves sloth relationships
Nature Ecology and Evolution, 2019, 3, 1121-1130
7.690Citations (PDF)
37Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression7.738Citations (PDF)
38Modular assembly of the nucleolar pre-60S ribosomal subunit
Nature, 2018, 556, 126-129
40.1110Citations (PDF)
39Integrative structure and functional anatomy of a nuclear pore complex
Nature, 2018, 555, 475-482
40.1348Citations (PDF)
40A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells
Cell Chemical Biology, 2018, 25, 110-120.e3
6.456Citations (PDF)
41The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination
Molecular Cell, 2018, 72, 636-649.e8
14.231Citations (PDF)
42Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown16.423Citations (PDF)
43Nuclear ARP2/3 drives DNA break clustering for homology-directed repair
Nature, 2018, 559, 61-66
40.1278Citations (PDF)
44Author response: Mechanisms of opening and closing of the bacterial replicative helicase
2018, ,
0Citations (PDF)
45The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators
Nucleic Acids Research, 2017, , gkw1288
16.218Citations (PDF)
46Gel filtration of dilute human embryonic hemoglobins reveals basis for their increased oxygen binding
Analytical Biochemistry, 2017, 519, 38-41
2.56Citations (PDF)
47Functional Plasticity of the AgrC Receptor Histidine Kinase Required for Staphylococcal Virulence
Cell Chemical Biology, 2017, 24, 76-86
6.419Citations (PDF)
48Lineage-specific proteins essential for endocytosis in trypanosomes
Journal of Cell Science, 2017, 130, 1379-1392
3.216Citations (PDF)
49The complete structure of the small-subunit processome6.4102Citations (PDF)
50The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis
PLoS Pathogens, 2017, 13, e1006063
4.530Citations (PDF)
51UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly14.160Citations (PDF)
52High-Efficiency Isolation of Nuclear Envelope Protein Complexes from Trypanosomes0.023Citations (PDF)
53Revealing Higher Order Protein Structure Using Mass Spectrometry2.743Citations (PDF)
54Phosphorylation-Dependent Targeting of <i>Tetrahymena</i> HP1 to Condensed Chromatin
MSphere, 2016, 1,
3.13Citations (PDF)
55Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform
Cell, 2016, 167, 1215-1228.e25
35.1114Citations (PDF)
56Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies3.739Citations (PDF)
57HIV–host interactome revealed directly from infected cells12.845Citations (PDF)
58Optimizing selection of large animals for antibody production by screening immune response to standard vaccines1.516Citations (PDF)
59A Robust Workflow for Native Mass Spectrometric Analysis of Affinity-Isolated Endogenous Protein Assemblies
Analytical Chemistry, 2016, 88, 2799-2807
6.719Citations (PDF)
60Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis7.756Citations (PDF)
61Affinity Proteomics to Study Endogenous Protein Complexes: Pointers, Pitfalls, Preferences and Perspectives
BioTechniques, 2015, 58, 103-119
5.541Citations (PDF)
62Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer
Journal of Biological Chemistry, 2015, 290, 30390-30405
2.322Citations (PDF)
63Architecture of a Host–Parasite Interface: Complex Targeting Mechanisms Revealed Through Proteomics4.845Citations (PDF)
64Beclin 1-Vps34 complex architecture: Understanding the nuts and bolts of therapeutic targets
Frontiers in Biology, 2015, 10, 398-426
0.949Citations (PDF)
65Rapid, optimized interactomic screening
Nature Methods, 2015, 12, 553-560
14.550Citations (PDF)
66A strategy for dissecting the architectures of native macromolecular assemblies
Nature Methods, 2015, 12, 1135-1138
14.596Citations (PDF)
67The architecture of a eukaryotic replisome6.4146Citations (PDF)
68β-Lactoglobulin detected in human milk forms noncovalent complexes with maltooligosaccharides as revealed by chip-nanoelectrospray high-resolution tandem mass spectrometry
Amino Acids, 2015, 47, 2399-2407
2.30Citations (PDF)
69Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response
Nature Chemical Biology, 2015, 11, 807-814
7.386Citations (PDF)
70NPC Mimics
Methods in Cell Biology, 2014, , 379-393
0.03Citations (PDF)
71Structural Characterization by Cross-linking Reveals the Detailed Architecture of a Coatomer-related Heptameric Module from the Nuclear Pore Complex4.8134Citations (PDF)
72Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit6.4103Citations (PDF)
73Integrative Structure–Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex4.858Citations (PDF)
74Molecular Architecture and Function of the SEA Complex, a Modulator of the TORC1 Pathway4.858Citations (PDF)
75Nrbf2 Protein Suppresses Autophagy by Modulating Atg14L Protein-containing Beclin 1-Vps34 Complex Architecture and Reducing Intracellular Phosphatidylinositol-3 Phosphate Levels
Journal of Biological Chemistry, 2014, 289, 26021-26037
2.358Citations (PDF)
76Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes7.724Citations (PDF)
77A Pipeline for Determining Protein–Protein Interactions and Proximities in the Cellular Milieu4.834Citations (PDF)
78A robust pipeline for rapid production of versatile nanobody repertoires
Nature Methods, 2014, 11, 1253-1260
14.5338Citations (PDF)
79Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition
Cell, 2013, 155, 1034-1048
35.1154Citations (PDF)
80Activation of DSB Processing Requires Phosphorylation of CtIP by ATR
Molecular Cell, 2013, 49, 657-667
14.2111Citations (PDF)
81Examining post‐translational modification‐mediated protein–protein interactions using a chemical proteomics approach
Protein Science, 2013, 22, 287-295
5.935Citations (PDF)
82The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome
Molecular Biology of the Cell, 2013, 24, 3920-3938
2.588Citations (PDF)
83Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes
Parasitology, 2012, 139, 1158-1167
2.012Citations (PDF)
84Structure–function mapping of a heptameric module in the nuclear pore complex
Journal of Cell Biology, 2012, 196, 419-434
4.896Citations (PDF)
85Transcriptional Regulation by Pol II(G) Involving Mediator and Competitive Interactions of Gdown1 and TFIIF with Pol II
Molecular Cell, 2012, 45, 51-63
14.257Citations (PDF)
86Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels
BioTechniques, 2012, ,
5.540Citations (PDF)
87High‐Throughput, Single‐Step Purification of Affinity‐Tagged Protein Complexes
FASEB Journal, 2012, 26,
0.70Citations (PDF)
88Protein Arginine Methyltransferase Prmt5-Mep50 Methylates Histones H2A and H4 and the Histone Chaperone Nucleoplasmin in Xenopus laevis Eggs
Journal of Biological Chemistry, 2011, 286, 42221-42231
2.346Citations (PDF)
89Conjugation of Magnetic Beads for Immunopurification of Protein Complexes
Cold Spring Harbor Protocols, 2011, 2011, pdb.prot5610
0.636Citations (PDF)
90Mass Spectrometry in the Postgenomic Era18.353Citations (PDF)
91High-capacity ion trap coupled to a time-of-flight mass spectrometer for comprehensive linked scans with no scanning losses1.64Citations (PDF)
92Global Analysis of Cdc14 Phosphatase Reveals Diverse Roles in Mitotic Processes
Journal of Biological Chemistry, 2011, 286, 5434-5445
2.355Citations (PDF)
93Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication
Journal of Virology, 2010, 84, 6720-6732
3.689Citations (PDF)
94<i>Escherichia coli</i> condensin MukB stimulates topoisomerase IV activity by a direct physical interaction7.779Citations (PDF)
95Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor4.8183Citations (PDF)
96Proteomic Studies of a Single CNS Synapse Type: The Parallel Fiber/Purkinje Cell Synapse
PLoS Biology, 2009, 7, e1000083
5.255Citations (PDF)
97Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
Nature Cell Biology, 2009, 11, 468-476
10.5819Citations (PDF)
98Rrp17p Is a Eukaryotic Exonuclease Required for 5′ End Processing of Pre-60S Ribosomal RNA
Molecular Cell, 2009, 36, 768-781
14.274Citations (PDF)
99Human Cytomegalovirus Protein UL38 Inhibits Host Cell Stress Responses by Antagonizing the Tuberous Sclerosis Protein Complex
Cell Host and Microbe, 2008, 3, 253-262
15.2166Citations (PDF)
100Rapid Isolation and Identification of Bacteriophage T4-Encoded Modifications of <i>Escherichia coli</i> RNA Polymerase: A Generic Method to Study Bacteriophage/Host Interactions
Journal of Proteome Research, 2008, 7, 1244-1250
3.714Citations (PDF)
101Efficient Identification of Phosphorylation by Mass Spectrometric Phosphopeptide Fingerprinting
Analytical Chemistry, 2008, 80, 2419-2425
6.713Citations (PDF)
102Affinity Isolation and I-DIRT Mass Spectrometric Analysis of the <i>Escherichia coli</i> O157:H7 Sakai RNA Polymerase Complex
Journal of Bacteriology, 2008, 190, 1284-1289
3.017Citations (PDF)
103A novel high-capacity ion trap-quadrupole tandem mass spectrometer1.66Citations (PDF)
104Comprehensive analysis of diverse ribonucleoprotein complexes
Nature Methods, 2007, 4, 951-956
14.5205Citations (PDF)
105Determining the architectures of macromolecular assemblies
Nature, 2007, 450, 683-694
40.1453Citations (PDF)
106The molecular architecture of the nuclear pore complex
Nature, 2007, 450, 695-701
40.1856Citations (PDF)
107Yng1 PHD Finger Binding to H3 Trimethylated at K4 Promotes NuA3 HAT Activity at K14 of H3 and Transcription at a Subset of Targeted ORFs
Molecular Cell, 2006, 24, 785-796
14.2261Citations (PDF)
108Simple fold composition and modular architecture of the nuclear pore complex7.7223Citations (PDF)
109The nuclear pore complex–associated protein, Mlp2p, binds to the yeast spindle pole body and promotes its efficient assembly
Journal of Cell Biology, 2005, 170, 225-235
4.872Citations (PDF)
110Fluorescent Proteins as Proteomic Probes4.8193Citations (PDF)
111I-DIRT, A General Method for Distinguishing between Specific and Nonspecific Protein Interactions
Journal of Proteome Research, 2005, 4, 1752-1756
3.7117Citations (PDF)
112A Method for the Rapid and Efficient Elution of Native Affinity-Purified Protein A Tagged Complexes
Journal of Proteome Research, 2005, 4, 2250-2256
3.715Citations (PDF)
113POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
Genes and Development, 2004, 18, 1649-1654
4.8355Citations (PDF)
114TIN2 Binds TRF1 and TRF2 Simultaneously and Stabilizes the TRF2 Complex on Telomeres
Journal of Biological Chemistry, 2004, 279, 47264-47271
2.3258Citations (PDF)
115Components of Coated Vesicles and Nuclear Pore Complexes Share a Common Molecular Architecture
PLoS Biology, 2004, 2, e380
5.2330Citations (PDF)
116Analysis of Protein Phosphorylation by Hypothesis-Driven Multiple-Stage Mass Spectrometry
Analytical Chemistry, 2004, 76, 4472-4483
6.764Citations (PDF)
117Targeted Proteomic Study of the Cyclin-Cdk Module
Molecular Cell, 2004, 14, 699-711
14.292Citations (PDF)
118A Modular Cross-Linking Approach for Exploring Protein Interactions15.7159Citations (PDF)
119Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry7.7100Citations (PDF)
120X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
Nature, 2002, 415, 287-294
40.11,410Citations (PDF)
121Automatic Identification of Proteins with a MALDI-Quadrupole Ion Trap Mass Spectrometer
Analytical Chemistry, 2001, 73, 5066-5077
6.7133Citations (PDF)
122Mass Spectrometry as a Tool for Protein Crystallography20.750Citations (PDF)
123Nup2p Dynamically Associates with the Distal Regions of the Yeast Nuclear Pore Complex
Journal of Cell Biology, 2001, 153, 1465-1478
4.8135Citations (PDF)
124A Robust, Detergent-Friendly Method for Mass Spectrometric Analysis of Integral Membrane Proteins
Analytical Chemistry, 2000, 72, 5655-5658
6.7152Citations (PDF)
125Rapidly switchable matrix-assisted laser desorption/ionization and electrospray quadrupole-time-of-flight mass spectrometry for protein identification2.7111Citations (PDF)
126The Yeast Nuclear Pore Complex
Journal of Cell Biology, 2000, 148, 635-652
4.81,214Citations (PDF)
127Title is missing!
Nature Structural Biology, 1999, 6, 615-619
8.987Citations (PDF)
128Title is missing!
Plant Molecular Biology, 1999, 40, 373-386
3.339Citations (PDF)
129Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels
Science, 1998, 280, 106-109
38.2388Citations (PDF)
130Identification and Characterization of Posttranslational Modifications of Proteins by MALDI Ion Trap Mass Spectrometry
Analytical Chemistry, 1997, 69, 4002-4009
6.7161Citations (PDF)
131Influence of Matrix Solution Conditions on the MALDI-MS Analysis of Peptides and Proteins
Analytical Chemistry, 1996, 68, 31-37
6.7463Citations (PDF)
132Structural similarity between TAFs and the heterotetrameric core of the histone octamer
Nature, 1996, 380, 316-322
40.1235Citations (PDF)
133Human leptin characterization
Nature, 1996, 382, 589-589
40.179Citations (PDF)
134Probing the solution structure of the DNA‐binding protein Max by a combination of proteolysis and mass spectrometry
Protein Science, 1995, 4, 1088-1099
5.9140Citations (PDF)
135Matrix‐assisted laser desorption mass spectrometric peptide mapping of proteins separated by two‐dimensional gel electrophoresis: Determination of phosphorylation in synapsin I
Protein Science, 1994, 3, 677-686
5.946Citations (PDF)
136Two‐step selective formation of three disulfide bridges in the synthesis of the C‐terminal epidermal growth factor‐like domain in human blood coagulation factor IX
Protein Science, 1994, 3, 1267-1275
5.956Citations (PDF)
137Mass spectrometry — a useful tool for the protein X-ray crystallographer and NMR spectroscopist
Structure, 1994, 2, 465-467
3.927Citations (PDF)
138Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry of Biopolymers
Analytical Chemistry, 1991, 63, 1193A-1203A
6.71,259Citations (PDF)
139Observation of the heme-globin complex in native myoglobin by electrospray-ionization mass spectrometry15.7431Citations (PDF)
140Probing conformational changes in proteins by mass spectrometry15.7587Citations (PDF)
141Dissection of affinity captured LINE-1 macromolecular complexes
ELife, 0, 7,
1.649Citations (PDF)
142Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake
ELife, 0, 10,
1.631Citations (PDF)
143Structural basis for transcription complex disruption by the Mfd translocase
ELife, 0, 10,
1.630Citations (PDF)
144Analysis of the mechanosensor channel functionality of TACAN
ELife, 0, 10,
1.625Citations (PDF)
145Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex
ELife, 0, 6,
1.689Citations (PDF)
146Mechanisms of opening and closing of the bacterial replicative helicase
ELife, 0, 7,
1.617Citations (PDF)
147Structural basis of substrate recognition by a polypeptide processing and secretion transporter
ELife, 0, 9,
1.626Citations (PDF)
148The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates
ELife, 0, 11,
1.66Citations (PDF)
149Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape
ELife, 0, 10,
1.643Citations (PDF)
150Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
ELife, 0, 11,
1.610Citations (PDF)