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186 PR articles • 34,423 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Calpastatin, a calpain specific inhibitor, reduce seizures in a mouse model of temporal lobe epilepsy
Epilepsia Open, 2025, 10, 957-964
2.80Citations (PDF)
2Profiling lamina specific pyramidal neurons using postmortem human formalin fixed paraffin embedded frontal cortex tissue in combination with digital spatial profiling2.20Citations (PDF)
3Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer’s Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration
Journal of Neuroscience, 2025, 45, e2331242025
3.71Citations (PDF)
4Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases78.2205Citations (PDF)
5Autophagy–lysosomal-associated neuronal death in neurodegenerative disease9.257Citations (PDF)
6Pathophysiologic abnormalities in transgenic mice carrying the Alzheimer disease <i>PSEN1</i> Δ440 mutation
Human Molecular Genetics, 2024, 33, 2051-2070
2.90Citations (PDF)
7Posttranscriptional regulation of neurofilament proteins and tau in health and disease
Brain Research Bulletin, 2023, 192, 115-127
3.414Citations (PDF)
8Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques
Nature Neuroscience, 2022, 25, 688-701
17.0537Citations (PDF)
9Autolysosomal acidification failure as a primary driver of Alzheimer disease pathogenesis
Autophagy, 2022, 18, 2763-2764
13.725Citations (PDF)
10The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease
Nature Neuroscience, 2022, 25, 1366-1378
17.051Citations (PDF)
11Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration13.753Citations (PDF)
12Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
Cell Reports, 2021, 35, 109034
6.389Citations (PDF)
13Alzheimer disease47.21,991Citations (PDF)
14Neurofilament Proteins as Biomarkers to Monitor Neurological Diseases and the Efficacy of Therapies2.7254Citations (PDF)
15Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 2021, 17, 1-382
13.72,296Citations (PDF)
16A gene toolbox for monitoring autophagy transcription8.5105Citations (PDF)
17Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer’s Disease
Cell Reports, 2020, 33, 108420
6.3106Citations (PDF)
18The aging lysosome: An essential catalyst for late-onset neurodegenerative diseases2.0128Citations (PDF)
19Neurofilaments: neurobiological foundations for biomarker applications
Brain, 2020, 143, 1975-1998
8.4286Citations (PDF)
20β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7
Journal of Molecular Biology, 2020, 432, 2633-2650
4.133Citations (PDF)
21Lysosome trafficking and signaling in health and neurodegenerative diseases
Neurobiology of Disease, 2019, 122, 94-105
5.1251Citations (PDF)
22mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy8.5103Citations (PDF)
23Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99)
Journal of Neuroscience, 2019, 39, 5255-5268
3.7146Citations (PDF)
24Transgenic expression of a ratiometric autophagy probe specifically in neurons enables the interrogation of brain autophagy <i>in vivo</i>
Autophagy, 2019, 15, 543-557
13.778Citations (PDF)
25Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease3.7154Citations (PDF)
26Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors5.252Citations (PDF)
27Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing79.9496Citations (PDF)
28Cyclodextrin has conflicting actions on autophagy flux in vivo in brains of normal and Alzheimer model mice
Human Molecular Genetics, 2017, , ddx001
2.930Citations (PDF)
29Neurofilaments and Neurofilament Proteins in Health and Disease7.2667Citations (PDF)
30Amyloid precursor protein and endosomal‐lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease
FASEB Journal, 2017, 31, 2729-2743
0.6352Citations (PDF)
31Calpastatin inhibits motor neuron death and increases survival of hSOD1G93A mice
Journal of Neurochemistry, 2016, 137, 253-265
3.843Citations (PDF)
32Specialized roles of neurofilament proteins in synapses: Relevance to neuropsychiatric disorders
Brain Research Bulletin, 2016, 126, 334-346
3.481Citations (PDF)
33Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
Autophagy, 2016, 12, 2467-2483
13.7319Citations (PDF)
34Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 2016, 12, 1-222
13.74,989Citations (PDF)
35Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification
Cell Reports, 2015, 12, 1430-1444
6.3333Citations (PDF)
36Early hyperactivity in lateral entorhinal cortex is associated with elevated levels of AβPP metabolites in the Tg2576 mouse model of Alzheimer's disease
Experimental Neurology, 2015, 264, 82-91
4.073Citations (PDF)
37Dissociation of Axonal Neurofilament Content from Its Transport Rate
PLoS ONE, 2015, 10, e0133848
2.313Citations (PDF)
38Spared Piriform Cortical Single-Unit Odor Processing and Odor Discrimination in the Tg2576 Mouse Model of Alzheimer's Disease
PLoS ONE, 2014, 9, e106431
2.318Citations (PDF)
39Specific Calpain Inhibition by Calpastatin Prevents Tauopathy and Neurodegeneration and Restores Normal Lifespan in Tau P301L Mice
Journal of Neuroscience, 2014, 34, 9222-9234
3.796Citations (PDF)
402014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease0.567Citations (PDF)
41Alzheimer neurodegeneration, autophagy, and Abeta secretion: The ins and outs (comment on DOI 10.1002/bies.201400002)
BioEssays, 2014, 36, 547-547
2.114Citations (PDF)
42Single-Walled Carbon Nanotubes Alleviate Autophagic/Lysosomal Defects in Primary Glia from a Mouse Model of Alzheimer’s Disease
Nano Letters, 2014, 14, 5110-5117
8.7124Citations (PDF)
43Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits
Brain, 2014, 137, 3300-3318
8.4105Citations (PDF)
44The role of autophagy in neurodegenerative disease
Nature Medicine, 2013, 19, 983-997
33.01,906Citations (PDF)
45Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
Neurobiology of Aging, 2013, 34, 137-145
3.436Citations (PDF)
46Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis13.7141Citations (PDF)
47Global Axonal Transport Rates are Unaltered in Htau Mice in vivo2.614Citations (PDF)
48Peripherin Is a Subunit of Peripheral Nerve Neurofilaments: Implications for Differential Vulnerability of CNS and Peripheral Nervous System Axons
Journal of Neuroscience, 2012, 32, 8501-8508
3.7115Citations (PDF)
49The Ubiquitin-Proteasome System and the Autophagic-Lysosomal System in Alzheimer Disease6.6162Citations (PDF)
50Neurofilaments at a glance
Journal of Cell Science, 2012, 125, 3257-3263
2.4368Citations (PDF)
51Calpastatin modulates APP processing in the brains of β-amyloid depositing but not wild-type mice
Neurobiology of Aging, 2012, 33, 1125.e9-1125.e18
3.414Citations (PDF)
52Autophagy and Neuronal Cell Death in Neurological Disorders7.2169Citations (PDF)
53Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 2012, 8, 445-544
13.73,229Citations (PDF)
54The C-Terminal Domains of NF-H and NF-M Subunits Maintain Axonal Neurofilament Content by Blocking Turnover of the Stationary Neurofilament Network
PLoS ONE, 2012, 7, e44320
2.335Citations (PDF)
55Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease2.0123Citations (PDF)
56Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments
Neurobiology of Aging, 2011, 32, 2016-2029
3.446Citations (PDF)
57Mechanisms of Neural and Behavioral Dysfunction in Alzheimer’s Disease
Molecular Neurobiology, 2011, 43, 163-179
3.716Citations (PDF)
58Autophagy failure in Alzheimer's disease—locating the primary defect
Neurobiology of Disease, 2011, 43, 38-45
5.1616Citations (PDF)
59Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
Journal of Neuroscience, 2011, 31, 7817-7830
3.7433Citations (PDF)
60Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
Brain, 2011, 134, 258-277
8.4419Citations (PDF)
61The Myosin Va Head Domain Binds to the Neurofilament-L Rod and Modulates Endoplasmic Reticulum (ER) Content and Distribution within Axons
PLoS ONE, 2011, 6, e17087
2.346Citations (PDF)
62Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease2.6119Citations (PDF)
63Alzheimer’s-related endosome dysfunction in Down syndrome is Aβ-independent but requires APP and is reversed by BACE-1 inhibition7.5285Citations (PDF)
64Rapamycin induces autophagic flux in neurons7.538Citations (PDF)
65Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
Human Molecular Genetics, 2010, 19, 3219-3232
2.9220Citations (PDF)
66Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression
Biological Psychiatry, 2010, 68, 885-893
5.4252Citations (PDF)
67The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models
NeuroImage, 2010, 51, 1098-1105
4.421Citations (PDF)
68Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
Cell, 2010, 141, 1146-1158
33.71,124Citations (PDF)
69Cystatin C Rescues Degenerating Neurons in a Cystatin B-Knockout Mouse Model of Progressive Myoclonus Epilepsy
American Journal of Pathology, 2010, 177, 2256-2267
3.455Citations (PDF)
70Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis
Journal of Neuroscience, 2010, 30, 14946-14954
3.7259Citations (PDF)
71Induction of Autophagy by Cystatin C: A Mechanism That Protects Murine Primary Cortical Neurons and Neuronal Cell Lines
PLoS ONE, 2010, 5, e9819
2.3112Citations (PDF)
72Complexes of Amyloid-β and Cystatin C in the Human Central Nervous System2.631Citations (PDF)
73Chapter 6 Monitoring Autophagy in Alzheimer's Disease and Related Neurodegenerative Diseases
Methods in Enzymology, 2009, , 111-144
2.134Citations (PDF)
74Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons
Journal of Neuroscience, 2009, 29, 11316-11329
3.7102Citations (PDF)
75Age‐dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model
Journal of Neurochemistry, 2009, 110, 1818-1827
3.884Citations (PDF)
76In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model
Neurobiology of Aging, 2009, 30, 1453-1465
3.452Citations (PDF)
77Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
Journal of Neuroscience, 2008, 28, 6926-6937
3.71,071Citations (PDF)
78Down Syndrome Fibroblast Model of Alzheimer-Related Endosome Pathology
American Journal of Pathology, 2008, 173, 370-384
3.4183Citations (PDF)
79Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease
American Journal of Pathology, 2008, 173, 665-681
3.4162Citations (PDF)
80Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression
Journal of Neuroscience, 2008, 28, 12241-12254
3.7100Citations (PDF)
81Neurodegenerative lysosomal disorders: A continuum from development to late age
Autophagy, 2008, 4, 590-599
13.7341Citations (PDF)
82Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease
Journal of Clinical Investigation, 2008, 118, 2796-2807
10.6200Citations (PDF)
83Cortical Plasticity in Alzheimer’s Disease in Humans and Rodents
Biological Psychiatry, 2007, 62, 1405-1412
5.4169Citations (PDF)
84Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models
Nature Genetics, 2007, 39, 1440-1442
25.2178Citations (PDF)
85Neuronal macroautophagy: From development to degeneration9.4156Citations (PDF)
86Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo
Neuroscience Letters, 2006, 393, 264-268
1.943Citations (PDF)
87Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
Neuron, 2006, 51, 29-42
11.0522Citations (PDF)
88Autophagy in neurodegenerative disease: friend, foe or turncoat?
Trends in Neurosciences, 2006, 29, 528-535
9.7315Citations (PDF)
89Lysosomal system pathways: Genes to neurodegeneration in Alzheimer's disease2.6221Citations (PDF)
90 -Internexin Is Structurally and Functionally Associated with the Neurofilament Triplet Proteins in the Mature CNS
Journal of Neuroscience, 2006, 26, 10006-10019
3.7217Citations (PDF)
91Histological Co-Localization of Iron in A� Plaques of PS/APP Transgenic Mice
Neurochemical Research, 2005, 30, 201-205
3.4119Citations (PDF)
92Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair
Autophagy, 2005, 1, 11-22
13.7432Citations (PDF)
93Extensive Involvement of Autophagy in Alzheimer Disease: An Immuno-Electron Microscopy Study1.81,420Citations (PDF)
94Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases
Neurobiology of Aging, 2005, 26, 373-382
3.4381Citations (PDF)
95Medical bioremediation: Prospects for the application of microbial catabolic diversity to aging and several major age-related diseases
Ageing Research Reviews, 2005, 4, 315-338
11.634Citations (PDF)
96Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
Journal of Cell Biology, 2005, 171, 87-98
5.4959Citations (PDF)
97Amyloid-β Deposition Is Associated with Decreased Hippocampal Glucose Metabolism and Spatial Memory Impairment in APP/PS1 Mice1.8114Citations (PDF)
98Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F2-isoprostanes in the absence of detectable amyloid deposits
Journal of Neurochemistry, 2004, 90, 1011-1018
3.841Citations (PDF)
99Overexpression of Human Cystatin C in Transgenic Mice Does Not Affect Levels of Endogenous Brain Amyloid β Peptide2.425Citations (PDF)
100MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease2.8110Citations (PDF)
101Visualization of ?-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents2.8100Citations (PDF)
102Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for β-amyloid peptide over-production and localization in Alzheimer’s disease2.6290Citations (PDF)
103Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome
Neurobiology of Aging, 2004, 25, 1263-1272
3.4363Citations (PDF)
104Calpain Mediates Calcium-Induced Activation of the Erk1,2 MAPK Pathway and Cytoskeletal Phosphorylation in Neurons
American Journal of Pathology, 2004, 165, 795-805
3.4127Citations (PDF)
105Presenilin Mutations in Familial Alzheimer Disease and Transgenic Mouse Models Accelerate Neuronal Lysosomal Pathology1.8148Citations (PDF)
106Calpain Inhibitors, a Treatment for Alzheimer's Disease: Position Paper2.464Citations (PDF)
107Title is missing!
Neurochemical Research, 2003, 28, 1041-1047
3.459Citations (PDF)
108The calpains in aging and aging-related diseases
Ageing Research Reviews, 2003, 2, 407-418
11.6206Citations (PDF)
109The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate
Journal of Cell Biology, 2003, 163, 1021-1031
5.4118Citations (PDF)
110Rab5-stimulated Up-regulation of the Endocytic Pathway Increases Intracellular β-Cleaved Amyloid Precursor Protein Carboxyl-terminal Fragment Levels and Aβ Production
Journal of Biological Chemistry, 2003, 278, 31261-31268
2.2213Citations (PDF)
111Neurofilament TransportIn VivoMinimally Requires Hetero-Oligomer Formation
Journal of Neuroscience, 2003, 23, 9452-9458
3.751Citations (PDF)
112Alzheimer's Disease-related Overexpression of the Cation-dependent Mannose 6-Phosphate Receptor Increases Aβ Secretion
Journal of Biological Chemistry, 2002, 277, 5299-5307
2.293Citations (PDF)
113Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density
Journal of Cell Biology, 2002, 159, 279-290
5.4107Citations (PDF)
114Calpain Activity Regulates the Cell Surface Distribution of Amyloid Precursor Protein
Journal of Biological Chemistry, 2002, 277, 36415-36424
2.298Citations (PDF)
115Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport
Journal of Cell Biology, 2002, 158, 681-693
5.4131Citations (PDF)
116P301L tauopathy2.126Citations (PDF)
117Calpain inhibitors2.453Citations (PDF)
118Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2
Acta Neuropathologica, 2002, 104, 92-104
9.2101Citations (PDF)
119Multiple-label immunocytochemistry for the evaluation of nature of cell death in experimental models of neurodegeneration
Brain Research Protocols, 2001, 7, 193-202
1.627Citations (PDF)
120The neuronal endosomal-lysosomal system in Alzheimer's disease2.6114Citations (PDF)
121Endocytic disturbances distinguish among subtypes of alzheimer's disease and related disorders
Annals of Neurology, 2001, 50, 661-665
6.684Citations (PDF)
122Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
Nature, 2000, 408, 979-982
37.91,505Citations (PDF)
123Title is missing!
Neurochemical Research, 2000, 25, 1161-1172
3.4316Citations (PDF)
124Local Control of Neurofilament Accumulation during Radial Growth of Myelinating Axons in Vivo
Journal of Cell Biology, 2000, 151, 1013-1024
5.4149Citations (PDF)
125Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
American Journal of Pathology, 2000, 157, 277-286
3.4831Citations (PDF)
126Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL
Neurobiology of Aging, 2000, 21, 511-524
3.480Citations (PDF)
127A “Protease Activation Cascade” in the Pathogenesis of Alzheimer's Disease4.093Citations (PDF)
128Isoform-specific translocation of protein kinase C following glutamate administration in primary hippocampal neurons
Molecular Brain Research, 1999, 64, 222-235
2.625Citations (PDF)
129Developmental regulation of the recovery process following glutamate-induced calcium rise in rodent primary neuronal cultures
Developmental Brain Research, 1998, 108, 101-110
2.120Citations (PDF)
130The slow axonal transport debate12.118Citations (PDF)
131Dynamic behavior and organization of cytoskeletal proteins in neurons: reconciling old and new findings
BioEssays, 1998, 20, 798-807
2.163Citations (PDF)
132Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death
Molecular Brain Research, 1998, 54, 35-48
2.666Citations (PDF)
133The slow axonal transport of cytoskeletal proteins3.992Citations (PDF)
134Immunocytochemistry of formalin-fixed human brain tissues: microwave irradiation of free-floating sections
Brain Research Protocols, 1998, 2, 109-119
1.633Citations (PDF)
135Caspase-Mediated Fragmentation of Calpain Inhibitor Protein Calpastatin during Apoptosis2.8250Citations (PDF)
136The Proteolytic Fragments of the Alzheimer's Disease-associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex
Journal of Biological Chemistry, 1998, 273, 3205-3211
2.2307Citations (PDF)
137Acute rise in the concentration of free cytoplasmic calcium leads to dephosphorylation of the microtubule-associated protein tau
Brain Research, 1997, 757, 93-101
2.537Citations (PDF)
138Triton-soluble phosphovariants of the heavy neurofilament subunit in developing and mature mouse central nervous system3.135Citations (PDF)
139Cellular Expression and Proteolytic Processing of Presenilin Proteins Is Developmentally Regulated During Neuronal Differentiation
Journal of Neurochemistry, 1997, 69, 2432-2440
3.881Citations (PDF)
140Colocalization of Lysosomal Hydrolase and β-Amyloid in Diffuse Plaques of the Cerebellum and Striatum in Alzheimerʼs Disease and Downʼs Syndrome1.872Citations (PDF)
141Calcium Influx into Human Neuroblastoma Cells Induces ALZ‐50 Immunoreactivity: Involvement of Calpain‐Mediated Hydrolysis of Protein Kinase C
Journal of Neurochemistry, 1996, 66, 1539-1549
3.855Citations (PDF)
142Aluminum treatment of intact neuroblastoma cells alters neurofilament subunit phosphorylation, solubility, and proteolysis0.915Citations (PDF)
143Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
Neuron, 1995, 14, 671-680
11.0359Citations (PDF)
144The endosomal-lysosomal system of neurons: new roles
Trends in Neurosciences, 1995, 18, 489-496
9.7150Citations (PDF)
145Proteolysis of protein kinase C: mM and μM calcium-requiring calpains have different abilities to generate, and degrade the free catalytic subunit, protein kinase M
FEBS Letters, 1995, 367, 223-227
2.764Citations (PDF)
146Purification and Properties of High Molecular Weight Calpastatin from Bovine Brain
Journal of Neurochemistry, 1995, 64, 859-866
3.819Citations (PDF)
147Enhancement of Neurite Outgrowth Following Calpain Inhibition Is Mediated by Protein Kinase C
Journal of Neurochemistry, 1995, 65, 517-527
3.842Citations (PDF)
148[32P]orthophosphate and [35S]methionine label separate pools of neurofilaments with markedly different axonal transport kinetics in mouse retinal ganglion cells in vivo
Neurochemical Research, 1994, 19, 1445-1453
3.429Citations (PDF)
149Degenerative changes in epinephrine tonic vasomotor neurons in Alzheimer's disease
Brain Research, 1994, 661, 35-42
2.546Citations (PDF)
150Free radicals, proteolysis, and the degeneration of neurons in alzheimer disease: How essential is the β-amyloid link?
Neurobiology of Aging, 1994, 15, 463-469
3.433Citations (PDF)
151Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease
Brain Research, 1994, 640, 68-80
2.5216Citations (PDF)
152Differential Expression and Subcellular Localization of Protein Kinase C ?, ?, ?, ?, and ? Isoforms in SH-SY5Y Neuroblastoma Cells: Modifications During Differentiation
Journal of Neurochemistry, 1993, 60, 289-298
3.875Citations (PDF)
153Specificity of calcium-activated neutral proteinase (CANP) inhibitors for human ?CANP and mCANP
Neurochemical Research, 1993, 18, 231-233
3.425Citations (PDF)
154The Lysosomal System in Neuronal Cell Death: A Review4.084Citations (PDF)
155The Regulation of Neurofilament Protein Dynamics by Phosphorylation: Clues to Neurofibrillary Pathobiology
Brain Pathology, 1993, 3, 29-38
5.0157Citations (PDF)
156Aluminum Alters the Electrophoretic Properties of Neurofilament Proteins: Role of Phosphorylation State
Journal of Neurochemistry, 1992, 58, 542-547
3.843Citations (PDF)
157Distinct Mechanisms of Differentiation of SH-SY5Y Neuroblastoma Cells by Protein Kinase C Activators and Inhibitors
Journal of Neurochemistry, 1992, 58, 1191-1198
3.854Citations (PDF)
158Immunoassay and Activity of Calcium-Activated Neutral Proteinase (mCANP): Distribution in Soluble and Membrane-Associated Fractions in Human and Mouse Brain
Journal of Neurochemistry, 1992, 58, 1526-1532
3.825Citations (PDF)
159Dynamics of neuronal intermediate filaments: A developmental perspective
Cytoskeleton, 1992, 22, 81-91
3.8212Citations (PDF)
160Neurofilament phosphorylation: a new look at regulation and function
Trends in Neurosciences, 1991, 14, 501-506
9.7308Citations (PDF)
161Multiple Proteases Regulate Neurite Outgrowth in NB2a/dl Neuroblastoma Cells
Journal of Neurochemistry, 1991, 56, 842-851
3.849Citations (PDF)
162Dynamics of Phosphorylation and Assembly of the High Molecular Weight Neurofilament Subunit in NB2a/d1 Neuroblastoma
Journal of Neurochemistry, 1990, 55, 1784-1792
3.858Citations (PDF)
163Aluminum Inhibits Calpain-Mediated Proteolysis and Induces Human Neurofilament Proteins to Form ProteaseResistant High Molecular Weight Complexes
Journal of Neurochemistry, 1990, 55, 1950-1959
3.874Citations (PDF)
164Post-translational modification of α-tubulin by acetylation and detyrosination in NB2a/d1 neuroblastoma cells
Developmental Brain Research, 1990, 51, 195-204
2.118Citations (PDF)
165Fluoxetine Versus Trazodone in Depressed Geriatric Patients
Topics in Geriatrics, 1989, 2, 208-214
0.958Citations (PDF)
166Early posttranslational modifications of the three neurofilament subunits in mouse retinal ganglion cells: neuronal sites and time course in relation to subunit polymerization and axonal transport
Molecular Brain Research, 1989, 5, 93-108
2.677Citations (PDF)
167Appearance and localization of phosphorylated variants of the high molecular weight neurofilament protein in NB2a/d1 cytoskeletons during differentiation
Developmental Brain Research, 1989, 50, 142-146
2.126Citations (PDF)
168Calcium-Activated Neutral Proteinases as Regulators of Cellular Function Implications for Alzheimer's Disease Pathogenesis4.071Citations (PDF)
169Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma
Brain Research, 1989, 492, 53-64
2.559Citations (PDF)
170Phosphorylation of neurofilament proteins by protein kinase C
FEBS Letters, 1988, 233, 181-185
2.766Citations (PDF)
171Neurofilament triplet proteins of NB2a/d1 neuroblastoma: posttranslational modification and incorporation into the cytoskeleton during differentiation2.163Citations (PDF)
172Differential distribution of vimentin and neurofilament protein immunoreactivity in NB2a/d1 neuroblastoma cells following neurite retraction distinguishes two separate intermediate filament systems
Developmental Brain Research, 1988, 41, 298-302
2.117Citations (PDF)
173Soluble, phosphorylated forms of the high molecular weight neurofilament protein in perikarya of cultured neuronal cells
Neuroscience Letters, 1988, 92, 291-297
1.932Citations (PDF)
174Cerebrospinal fluid levels of angiotensin- converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: A correlative study
Biological Psychiatry, 1986, 21, 1365-1381
5.472Citations (PDF)
175A versatile transition metal salt reaction for a wide range of common biochemical reagents: An instantaneous and quantifiable color test
Analytical Biochemistry, 1986, 154, 691-701
2.43Citations (PDF)
176Calcium‐Activated Neutral Proteinase of Human Brain: Subunit Structure and Enzymatic Properties of Multiple Molecular Forms
Journal of Neurochemistry, 1986, 47, 1039-1051
3.848Citations (PDF)
177Captopril and teprotide as discriminators of angiotensin-converting enzyme activity in brain tissue
Neuroscience Letters, 1985, 60, 33-37
1.96Citations (PDF)
178Cerebrospinal fluid levels of angiotensin-converting enzyme in Alzheimer's disease, Parkinson's disease and progressive supranuclear palsy
Brain Research, 1985, 328, 215-221
2.590Citations (PDF)
179Degradation of Neurofilament Proteins by Purified Human Brain Cathepsin D
Journal of Neurochemistry, 1984, 43, 507-516
3.886Citations (PDF)
180Proteases of human brain
Neurochemical Research, 1984, 9, 291-323
3.440Citations (PDF)
181Limited proteolytic modification of a neurofilament protein involves a proteinase activated by endogenous levels of calcium
Brain Research, 1983, 275, 384-388
2.551Citations (PDF)
182Protease activities in normal and schizophrenic human prefrontal cortex and white matter
Neurochemical Research, 1981, 6, 1043-1052
3.410Citations (PDF)
183Characterization and Comparison of Neurofilament Proteins from Rat and Mouse CNS
Journal of Neurochemistry, 1981, 36, 143-153
3.864Citations (PDF)
184Protein degradation in the mouse visual system I. Degradation of axonally transported and retinal proteins
Brain Research, 1980, 200, 69-83
2.576Citations (PDF)
185Uptake and metabolism of intraventricularly administered piperidine and its effects on sleep and wakefulness in the rat
Brain Research, 1977, 134, 501-511
2.57Citations (PDF)
186Neurotoxicity of a non-metabolizable amino acid, 1-aminocyclopentane-1-carboxylic acid (ACPC): ACPC transport mechanisms in tissues
Biochemical Pharmacology, 1976, 25, 726-729
5.14Citations (PDF)