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388 PR articles • 75,580 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Nature, 2024, 627, 347-357
37.9383Citations (PDF)
2Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure
Kidney International Reports, 2024, 9, 1849-1859
2.53Citations (PDF)
3SMIM1 absence is associated with reduced energy expenditure and excess weight
Med, 2024, 5, 1083-1095.e6
7.05Citations (PDF)
4Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity
Stroke, 2023, 54, 810-818
6.025Citations (PDF)
5Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH
Diabetologia, 2023, 66, 1260-1272
7.610Citations (PDF)
6A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections
Scientific Reports, 2022, 12,
3.416Citations (PDF)
7Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations3.831Citations (PDF)
8Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes
Genome Medicine, 2022, 14,
9.615Citations (PDF)
9Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Nature Genetics, 2022, 54, 560-572
25.2616Citations (PDF)
10A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids6.540Citations (PDF)
11Stroke genetics informs drug discovery and risk prediction across ancestries
Nature, 2022, 611, 115-123
37.9489Citations (PDF)
12Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Genome Biology, 2022, 23,
8.144Citations (PDF)
13Plasma proteomics and lung function in four community-based cohorts
Respiratory Medicine, 2021, 176, 106282
2.69Citations (PDF)
14Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability13.7132Citations (PDF)
15Fatty Liver Index and Development of Cardiovascular Disease: Findings from the UK Biobank
Digestive Diseases and Sciences, 2021, 66, 2092-2100
2.140Citations (PDF)
16The trans-ancestral genomic architecture of glycemic traits
Nature Genetics, 2021, 53, 840-860
25.2650Citations (PDF)
17A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids13.732Citations (PDF)
18Clinical Conditions and Their Impact on Utility of Genetic Scores for Prediction of Acute Coronary Syndrome2.96Citations (PDF)
19Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study
PLoS ONE, 2021, 16, e0255801
2.344Citations (PDF)
20Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases
JAMA Network Open, 2021, 4, e2034461
6.676Citations (PDF)
21The power of genetic diversity in genome-wide association studies of lipids
Nature, 2021, 600, 675-679
37.9845Citations (PDF)
22Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure13.7745Citations (PDF)
23A Multi-Cohort Metabolomics Analysis Discloses Sphingomyelin (32:1) Levels to be Inversely Related to Incident Ischemic Stroke1.622Citations (PDF)
24Changes in Proteomic Profiles are Related to Changes in BMI and Fat Distribution During 10 Years of Aging
Obesity, 2020, 28, 178-186
4.020Citations (PDF)
25Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Nature Metabolism, 2020, 2, 1135-1148
17.1609Citations (PDF)
26Non-targeted urine metabolomics and associations with prevalent and incident type 2 diabetes
Scientific Reports, 2020, 10,
3.415Citations (PDF)
27Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach
Scientific Reports, 2020, 10,
3.419Citations (PDF)
28Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Nature Genetics, 2020, 52, 1314-1332
25.2167Citations (PDF)
29Development and validation of risk prediction models for multiple cardiovascular diseases and Type 2 diabetes
PLoS ONE, 2020, 15, e0235758
2.319Citations (PDF)
30Adults With Mild‐to‐Moderate Congenital Heart Disease Demonstrate Measurable Neurocognitive Deficits4.022Citations (PDF)
31Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events2.927Citations (PDF)
32Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Diabetes, 2020, 69, 2806-2818
4.252Citations (PDF)
33Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus2.910Citations (PDF)
34Proteomic profiles before and during weight loss: Results from randomized trial of dietary intervention
Scientific Reports, 2020, 10,
3.436Citations (PDF)
35Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction13.7105Citations (PDF)
36Global Plasma Metabolomics to Identify Potential Biomarkers of Blood Pressure Progression6.051Citations (PDF)
37Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade7.5120Citations (PDF)
38FAM13A affects body fat distribution and adipocyte function13.757Citations (PDF)
39Accuracy of Smartphone Camera Applications for Detecting Atrial Fibrillation
JAMA Network Open, 2020, 3, e202064
6.687Citations (PDF)
40The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation
Atherosclerosis, 2020, 295, 25-30
1.524Citations (PDF)
41Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis
Nature Nanotechnology, 2020, 15, 154-161
32.2257Citations (PDF)
42Prevalence, characteristics and mortality outcomes of obese, nonobese and lean NAFLD in the United States, 1999–2016
Journal of Internal Medicine, 2020, 288, 139-151
7.3216Citations (PDF)
43Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank
Hypertension, 2020, 75, 714-722
6.646Citations (PDF)
44A phenome-wide association study of 26 mendelian genes reveals phenotypic expressivity of common and rare variants within the general population
PLoS Genetics, 2020, 16, e1008802
3.216Citations (PDF)
45Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies
PLoS ONE, 2020, 15, e0241558
2.38Citations (PDF)
46Personalized prediction of adverse heart and kidney events using baseline and longitudinal data from SPRINT and ACCORD
PLoS ONE, 2019, 14, e0219728
2.35Citations (PDF)
47Dog Ownership and Survival After a Major Cardiovascular Event4.129Citations (PDF)
48Disentangling the genetics of lean mass4.747Citations (PDF)
49Body composition and atrial fibrillation: a Mendelian randomization study
European Heart Journal, 2019, 40, 1277-1282
2.253Citations (PDF)
50Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK92.036Citations (PDF)
51CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation2.97Citations (PDF)
52Genetic regulation of gene expression and splicing during a 10-year period of human aging
Genome Biology, 2019, 20,
8.180Citations (PDF)
53Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology13.774Citations (PDF)
54Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria13.7207Citations (PDF)
55Detailed Functional Characterization of a Waist-Hip Ratio Locus in 7p15.2 Defines an Enhancer Controlling Adipocyte Differentiation
IScience, 2019, 20, 42-59
3.66Citations (PDF)
56Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels
Nature Genetics, 2019, 51, 1459-1474
25.2363Citations (PDF)
57Proteomic Analysis of Longitudinal Changes in Blood Pressure2.55Citations (PDF)
58Serum magnesium and calcium levels in relation to ischemic stroke
Neurology, 2019, 92,
1.053Citations (PDF)
59Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data13.7297Citations (PDF)
60Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology6.523Citations (PDF)
61The metabolites urobilin and sphingomyelin (30:1) are associated with incident heart failure in the general population
ESC Heart Failure, 2019, 6, 764-773
3.233Citations (PDF)
62A catalog of genetic loci associated with kidney function from analyses of a million individuals
Nature Genetics, 2019, 51, 957-972
25.2796Citations (PDF)
63Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts
Nature Medicine, 2019, 25, 911-919
33.0303Citations (PDF)
64Abundant associations with gene expression complicate GWAS follow-up
Nature Genetics, 2019, 51, 768-769
25.2351Citations (PDF)
65Impact of race/ethnicity on insulin resistance and hypertriglyceridaemia2.775Citations (PDF)
66Trends in overall, cardiovascular and cancer-related mortality among individuals with diabetes reported on death certificates in the United States between 2007 and 2017
Diabetologia, 2019, 62, 1185-1194
7.626Citations (PDF)
67Cardiometabolic Proteins Associated with Metabolic Syndrome1.913Citations (PDF)
68Substantial Cardiovascular Morbidity in Adults With Lower-Complexity Congenital Heart Disease
Circulation, 2019, 139, 1889-1899
18.1110Citations (PDF)
69Longitudinal effects of aging on plasma proteins levels in older adults – associations with kidney function and hemoglobin levels
PLoS ONE, 2019, 14, e0212060
2.323Citations (PDF)
70Dog ownership and cardiovascular risk factors: a nationwide prospective register-based cohort study
BMJ Open, 2019, 9, e023447
1.94Citations (PDF)
71Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion
Kidney International, 2019, 95, 1197-1208
5.343Citations (PDF)
72No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation
Diabetologia, 2019, 62, 800-804
7.624Citations (PDF)
73Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Nature Genetics, 2019, 51, 452-469
25.2106Citations (PDF)
74Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation2.92Citations (PDF)
75Proteomic profiling of endothelium-dependent vasodilation
Journal of Hypertension, 2019, 37, 216-222
2.23Citations (PDF)
76Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
PLoS Medicine, 2019, 16, e1002982
8.144Citations (PDF)
77Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies13.7136Citations (PDF)
78Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection2.3180Citations (PDF)
79Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Neurology, 2019, 92,
1.042Citations (PDF)
80Loss of function, missense, and intronic variants in <i>NOTCH1</i> confer different risks for left ventricular outflow tract obstructive heart defects in two European cohorts
Genetic Epidemiology, 2019, 43, 215-226
3.132Citations (PDF)
81A Nationwide Study of Inpatient Admissions, Mortality, and Costs for Patients with Cirrhosis from 2005 to 2015 in the USA
Digestive Diseases and Sciences, 2019, 65, 1520-1528
2.130Citations (PDF)
82Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank3.4100Citations (PDF)
83Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study13.7117Citations (PDF)
84Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Nature Genetics, 2018, 50, 559-571
25.2429Citations (PDF)
85Associations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease
Circulation, 2018, 137, 2583-2591
18.1229Citations (PDF)
86Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels13.7357Citations (PDF)
87Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development6.5105Citations (PDF)
88Methylation‐based estimated biological age and cardiovascular disease3.198Citations (PDF)
89A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia
Human Molecular Genetics, 2018, 27, 1809-1818
2.96Citations (PDF)
90Targeted proteomic analysis of habitual coffee consumption
Journal of Internal Medicine, 2018, 283, 200-211
7.311Citations (PDF)
91Circulating Proteins as Predictors of Incident Heart Failure in the Elderly7.4112Citations (PDF)
92Big Data and medicine: a big deal?
Journal of Internal Medicine, 2018, 283, 418-429
7.353Citations (PDF)
93GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes13.7160Citations (PDF)
94Genome-Wide Association Studies of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue in Elderly Individuals: Associations with Insulin Sensitivity
Nutrients, 2018, 10, 1791
4.528Citations (PDF)
95Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
Nature Genetics, 2018, 50, 1505-1513
25.21,673Citations (PDF)
96Clinical and Genetic Determinants of Varicose Veins
Circulation, 2018, 138, 2869-2880
18.1145Citations (PDF)
97Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins
Epigenetics, 2018, 13, 975-987
3.093Citations (PDF)
98Associations of Circulating Protein Levels With Lipid Fractions in the General Population6.024Citations (PDF)
99Large-Scale Phenome-Wide Association Study of <i>PCSK9</i> Variants Demonstrates Protection Against Ischemic Stroke2.958Citations (PDF)
100Genome Analyses of &gt;200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders6.5416Citations (PDF)
101Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease2.9109Citations (PDF)
102Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Nature Genetics, 2018, 50, 1412-1425
25.21,300Citations (PDF)
103Can the Plasma Concentration Ratio of Triglyceride/High-Density Lipoprotein Cholesterol Identify Individuals at High Risk of Cardiovascular Disease During 40-Year Follow-Up?1.916Citations (PDF)
104Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants3.446Citations (PDF)
105Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation2.255Citations (PDF)
106Multiplex proteomics for prediction of major cardiovascular events in type 2 diabetes
Diabetologia, 2018, 61, 1748-1757
7.654Citations (PDF)
107Bioimpedance and New‐Onset Heart Failure: A Longitudinal Study of &gt;500 000 Individuals From the General Population4.046Citations (PDF)
108Role of peroxisome proliferator-activated receptor gamma Pro12Ala polymorphism in human adipose tissue: assessment of adipogenesis and adipocyte glucose and lipid turnover
Adipocyte, 2018, 7, 285-296
3.07Citations (PDF)
109Genome-wide association study of coronary artery disease among individuals with diabetes: the UK Biobank
Diabetologia, 2018, 61, 2174-2179
7.640Citations (PDF)
110Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci6.595Citations (PDF)
111Circulating endostatin and the incidence of heart failure0.813Citations (PDF)
112Human Genetics of Obesity and Type 2 Diabetes Mellitus2.974Citations (PDF)
113Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance3.461Citations (PDF)
114Multi-ethnic genome-wide association study for atrial fibrillation
Nature Genetics, 2018, 50, 1225-1233
25.2728Citations (PDF)
115Identification of metabolic profiles associated with human exposure to perfluoroalkyl substances4.073Citations (PDF)
116Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Nature Genetics, 2018, 50, 524-537
25.21,550Citations (PDF)
117Meta-analysis of exome array data identifies six novel genetic loci for lung function0.912Citations (PDF)
118Meta-analysis of exome array data identifies six novel genetic loci for lung function0.91Citations (PDF)
119Meta-analysis of exome array data identifies six novel genetic loci for lung function0.921Citations (PDF)
120Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults4.917Citations (PDF)
121Sparse estimation of gene–gene interactions in prediction models1.72Citations (PDF)
122Genetic evidence of assortative mating in humans9.1308Citations (PDF)
123Association of Pregnancy Complications and Characteristics With Future Risk of Elevated Blood Pressure
Hypertension, 2017, 69, 475-483
6.656Citations (PDF)
124Rare and low-frequency coding variants alter human adult height
Nature, 2017, 542, 186-190
37.9612Citations (PDF)
125Epigenetic Patterns in Blood Associated With Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results From Genome-Wide Association Studies3.8124Citations (PDF)
126Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Nature Genetics, 2017, 49, 946-952
25.2336Citations (PDF)
127Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions
Circulation, 2017, 135, 2336-2353
18.159Citations (PDF)
128Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits13.7198Citations (PDF)
129PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study21.8349Citations (PDF)
130Genetic loci associated with heart rate variability and their effects on cardiac disease risk13.7114Citations (PDF)
131Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants
Epidemiology, 2017, 28, 30-42
2.81,688Citations (PDF)
132Leveraging Human Genetics to Understand the Relation of LDL Cholesterol with Type 2 Diabetes
Clinical Chemistry, 2017, 63, 1187-1189
1.14Citations (PDF)
133Tea and coffee consumption in relation to DNA methylation in four European cohorts
Human Molecular Genetics, 2017, 26, 3221-3231
2.930Citations (PDF)
134An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Diabetes, 2017, 66, 2888-2902
4.2717Citations (PDF)
135Alterations in Multiple Lifestyle Factors in Subjects with the Metabolic Syndrome Independently of Obesity1.910Citations (PDF)
136A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Diabetes, 2017, 66, 2019-2032
4.251Citations (PDF)
137COL4A2 is associated with lacunar ischemic stroke and deep ICH
Neurology, 2017, 89, 1829-1839
1.076Citations (PDF)
138New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals3.852Citations (PDF)
139Vitamin D and cognitive function: A Mendelian randomisation study3.456Citations (PDF)
140Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Hypertension, 2017, 70,
6.6143Citations (PDF)
141Use of Proteomics To Investigate Kidney Function Decline over 5 Years4.261Citations (PDF)
142Association analyses based on false discovery rate implicate new loci for coronary artery disease
Nature Genetics, 2017, 49, 1385-1391
25.2679Citations (PDF)
143Large meta-analysis of genome-wide association studies identifies five loci for lean body mass13.7168Citations (PDF)
144The Expressed Genome in Cardiovascular Diseases and Stroke: Refinement, Diagnosis, and Prediction: A Scientific Statement From the American Heart Association3.827Citations (PDF)
145Dog ownership and the risk of cardiovascular disease and death – a nationwide cohort study3.4137Citations (PDF)
146Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes3.463Citations (PDF)
147Genotype–covariate interaction effects and the heritability of adult body mass index
Nature Genetics, 2017, 49, 1174-1181
25.2159Citations (PDF)
148Transcriptional Dynamics During Human Adipogenesis and Its Link to Adipose Morphology and Distribution
Diabetes, 2017, 66, 218-230
4.234Citations (PDF)
149Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p′-dde levels in a population-based sample
Environment International, 2017, 98, 212-218
10.28Citations (PDF)
150Metabolic Syndrome Development During Aging with Special Reference to Obesity Without the Metabolic Syndrome1.922Citations (PDF)
151Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Scientific Data, 2017, 4,
5.736Citations (PDF)
152Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
PLoS Medicine, 2017, 14, e1002383
8.1400Citations (PDF)
153Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach
PLoS Medicine, 2017, 14, e1002215
8.1307Citations (PDF)
154Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation
Atherosclerosis, 2017, 266, 196-204
1.53Citations (PDF)
155Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Nature Genetics, 2017, 50, 26-41
25.2387Citations (PDF)
156Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
Journal of Clinical Investigation, 2017, 127, 1798-1812
10.6126Citations (PDF)
157Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
PLoS Genetics, 2017, 13, e1006706
3.2336Citations (PDF)
158Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions
PLoS Genetics, 2017, 13, e1006812
3.230Citations (PDF)
159Protein Biomarkers for Insulin Resistance and Type 2 Diabetes Risk in Two Large Community Cohorts
Diabetes, 2016, 65, 276-284
4.2110Citations (PDF)
160The genetic architecture of type 2 diabetes
Nature, 2016, 536, 41-47
37.91,051Citations (PDF)
161Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies
Lancet Neurology, The, 2016, 15, 695-707
17.9153Citations (PDF)
162Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity6.572Citations (PDF)
163Cystatin C and Cardiovascular Disease2.3134Citations (PDF)
164Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies
Atherosclerosis, 2016, 254, 52-58
1.525Citations (PDF)
165Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior
Human Molecular Genetics, 2016, , ddw334
2.9128Citations (PDF)
166Enabling Efficient and Confident Annotation of LC−MS Metabolomics Data through MS1 Spectrum and Time Prediction
Analytical Chemistry, 2016, 88, 9226-9234
6.592Citations (PDF)
167DNA methylation patterns associated with oxidative stress in an ageing population1.749Citations (PDF)
168Statistical power considerations in genotype-based recall randomized controlled trials3.413Citations (PDF)
169Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Nature Genetics, 2016, 48, 1151-1161
25.2298Citations (PDF)
170The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Nature Genetics, 2016, 48, 1171-1184
25.2410Citations (PDF)
171Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
Diabetes, 2016, 65, 3200-3211
4.276Citations (PDF)
172Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes
Diabetologia, 2016, 59, 2114-2124
7.695Citations (PDF)
173No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis3.430Citations (PDF)
174ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease
JAMA Internal Medicine, 2016, 176, 1155
10.5377Citations (PDF)
175Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study
Lancet Neurology, The, 2016, 15, 174-184
17.9241Citations (PDF)
176Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
Science, 2016, 351, 1166-1171
36.2506Citations (PDF)
177New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk13.7278Citations (PDF)
178Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels13.7173Citations (PDF)
179Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models3.78Citations (PDF)
180Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function13.7493Citations (PDF)
181The metabolic fingerprint of p,p′-DDE and HCB exposure in humans
Environment International, 2016, 88, 60-66
10.265Citations (PDF)
182Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation
Nature Genetics, 2016, 49, 125-130
25.2128Citations (PDF)
183A DNA methylation biomarker of alcohol consumption
Molecular Psychiatry, 2016, 23, 422-433
7.8349Citations (PDF)
184Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies
PLoS Genetics, 2016, 12, e1005874
3.262Citations (PDF)
185Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study
PLoS Genetics, 2016, 12, e1006379
3.224Citations (PDF)
186No Evidence of a Causal Relationship between Plasma Homocysteine and Type 2 Diabetes: A Mendelian Randomization Study2.525Citations (PDF)
187The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
PLoS Genetics, 2015, 11, e1005378
3.2393Citations (PDF)
188Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation
PLoS Genetics, 2015, 11, e1005230
3.284Citations (PDF)
189Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene
Journal of Clinical Investigation, 2015, 125, 1739-1751
10.6111Citations (PDF)
190Adiposity as a cause of cardiovascular disease: a Mendelian randomization study4.9136Citations (PDF)
191The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects
Molecular Psychiatry, 2015, 20, 735-743
7.874Citations (PDF)
1925 year mortality predictors in 498 103 UK Biobank participants: a prospective population-based study
Lancet, The, 2015, 386, 533-540
62.3382Citations (PDF)
193Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry
Human Molecular Genetics, 2015, 24, 4728-4738
2.995Citations (PDF)
194Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation13.7125Citations (PDF)
195New genetic loci link adipose and insulin biology to body fat distribution
Nature, 2015, 518, 187-196
37.91,561Citations (PDF)
196Genetic studies of body mass index yield new insights for obesity biology
Nature, 2015, 518, 197-206
37.94,431Citations (PDF)
197GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb
Atherosclerosis, 2015, 239, 304-310
1.533Citations (PDF)
198Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility13.7186Citations (PDF)
199Skeletal muscle morphology and risk of cardiovascular disease in elderly men2.010Citations (PDF)
200Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors
Diabetes, 2015, 64, 1841-1852
4.271Citations (PDF)
201Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis
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202Directional dominance on stature and cognition in diverse human populations
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203Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes
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204Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
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205The impact of low-frequency and rare variants on lipid levels
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206Genome-wide association study of plasma levels of polychlorinated biphenyls disclose an association with the CYP2B6 gene in a population-based sample
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207Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals
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208Genetically Determined Height and Coronary Artery Disease
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209Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity
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210Early Exposure to Dogs and Farm Animals and the Risk of Childhood Asthma
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211Genome-wide genetic homogeneity between sexes and populations for human height and body mass index
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212Genome-wide association study of toxic metals and trace elements reveals novel associations
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213Sex‐Specific Effects of Adiponectin on Carotid Intima‐Media Thickness and Incident Cardiovascular Disease4.034Citations (PDF)
214Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma13.7109Citations (PDF)
215Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
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216Population genetic differentiation of height and body mass index across Europe
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217A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
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218Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
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219Rediscovery rate estimation for assessing the validation of significant findings in high-throughput studies
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220Large-scale non-targeted metabolomic profiling in three human population-based studies
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221Genome‐Wide Association Studies (GWAS) of Estimated Fatty Acid Desaturase Activity in Serum and Adipose Tissue: Relationships with Insulin Sensitivity
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222Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function
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223The Grand Challenge of Cardiovascular Epidemiology: Turning the Tide2.50Citations (PDF)
224Common Familial Effects on Ischemic Stroke and Myocardial Infarction: A Prospective Population-Based Cohort Study2.50Citations (PDF)
225The association between glomerular filtration rate and left ventricular function in two independent community-based cohorts of elderly0.828Citations (PDF)
226Dose–Response Relationship of Total and Leisure Time Physical Activity to Risk of Heart Failure
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227Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity
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228Plasma–Parathyroid Hormone Is Associated With Subclinical and Clinical Atherosclerotic Disease in 2 Community-Based Cohorts6.064Citations (PDF)
229Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease
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230A Central Role for GRB10 in Regulation of Islet Function in Man
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231Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort8.444Citations (PDF)
232Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
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233Urinary Kidney Injury Molecule-1 and the Risk of Cardiovascular Mortality in Elderly Men4.227Citations (PDF)
234FTO genetic variants and risk of obesity and type 2 diabetes: A meta‐analysis of 28,394 Indians
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235Genetic factors may play a prominent role in the development of coronary heart disease dependent on important environmental factors
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236DNA mismatch repair gene MSH6 implicated in determining age at natural menopause
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237Interplay of overweight and insulin resistance on hypertension development
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238Differential association of chronic obstructive pulmonary disease with myocardial infarction and ischemic stroke in a nation-wide cohort2.229Citations (PDF)
239Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer
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240Persistent organic pollutants and liver dysfunction biomarkers in a population-based human sample of men and women
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241Genome-wide association analysis identifies six new loci associated with forced vital capacity
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242Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
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243Fat Mass and Obesity-Associated Gene (FTO) Is Linked to Higher Plasma Levels of the Hunger Hormone Ghrelin and Lower Serum Levels of the Satiety Hormone Leptin in Older Adults
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244Defining the role of common variation in the genomic and biological architecture of adult human height
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245Cerebrovascular and ischemic heart disease in young adults born preterm: a population-based Swedish cohort study5.395Citations (PDF)
246Influence of persistent organic pollutants on the complement system in a population-based human sample
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247Genetic variation in the CYP2B6 Gene is related to circulating 2,2’,4,4’-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study5.212Citations (PDF)
248Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study21.8347Citations (PDF)
249Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
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250Serum selenium in relation to measures of glucose metabolism and incidence of Type 2 diabetes in an older Swedish population
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251Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
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252Soluble tumor necrosis factor receptor 1 (sTNFR1) is associated with increased total mortality due to cancer and cardiovascular causes – Findings from two community based cohorts of elderly
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253Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
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254Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity
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255Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample
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256Influence of persistent organic pollutants on oxidative stress in population-based samples
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257Genome-wide association studies of obesity and metabolic syndrome3.4269Citations (PDF)
258Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption
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259Temporal Trends in Incidence of Myocardial Infarction and Ischemic Stroke by Socioeconomic Position in Sweden 1987–2010
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260Oxidative stress and inflammatory markers in relation to circulating levels of adiponectin
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261Clinical depression, antidepressant use and risk of future cardiovascular disease5.346Citations (PDF)
262Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics6.565Citations (PDF)
263Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs6.5110Citations (PDF)
264Urinary neutrophil gelatinase-associated lipocalin (NGAL) is associated with mortality in a community-based cohort of older Swedish men
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265Evidence of a Causal Relationship Between Adiponectin Levels and Insulin Sensitivity
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266Discovery and refinement of loci associated with lipid levels
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267Common variants associated with plasma triglycerides and risk for coronary artery disease
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268Meta-Analysis Investigating Associations Between Healthy Diet and Fasting Glucose and Insulin Levels and Modification by Loci Associated With Glucose Homeostasis in Data From 15 Cohorts3.382Citations (PDF)
269Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?
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271Global DNA hypermethylation is associated with high serum levels of persistent organic pollutants in an elderly population
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272Sortilin receptor 1 predicts longitudinal cognitive change
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273The leukotriene receptor antagonist montelukast and aortic stenosis2.65Citations (PDF)
274Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
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275Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
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276Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts
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277Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
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278Serum FGF23 and Risk of Cardiovascular Events in Relation to Mineral Metabolism and Cardiovascular Pathology4.2108Citations (PDF)
279Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
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280Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction6.0150Citations (PDF)
281The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
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282Association Between Circulating Endostatin, Hypertension Duration, and Hypertensive Target-Organ Damage
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283Serum Endostatin and Risk of Mortality in the Elderly6.043Citations (PDF)
284Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies
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285A common variant in the FTO locus is associated with waist–hip ratio in Indian adolescents2.517Citations (PDF)
286Urinary Kidney Injury Molecule 1 and Incidence of Heart Failure in Elderly men7.436Citations (PDF)
287A Genome-Wide Assessment of Variability in Human Serum Metabolism
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288Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes
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289Higher fibroblast growth factor-23 increases the risk of all-cause and cardiovascular mortality in the community
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290Genetic variation in the dimethylarginine dimethylaminohydrolase 1 gene (DDAH1) is related to asymmetric dimethylarginine (ADMA) levels, but not to endothelium-dependent vasodilation
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291Genetic Variants from Lipid-Related Pathways and Risk for Incident Myocardial Infarction
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292Utilizing Twins as Controls for Non-Twin Case-Materials in Genome Wide Association Studies
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293Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals
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294Smokeless tobacco (snus) and risk of heart failure: results from two Swedish cohorts2.045Citations (PDF)
295Risk Prediction Measures for Case-Cohort and Nested Case-Control Designs: An Application to Cardiovascular Disease3.382Citations (PDF)
296C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction
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297Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
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298Familial Effects on Ischemic Stroke3.810Citations (PDF)
299Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis4.9251Citations (PDF)
300Cyclooxygenase-2 inhibitors and cardiovascular risk in a nation-wide cohort study after the withdrawal of rofecoxib
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301Subfertility and risk of later life maternal cardiovascular disease
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302Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
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303Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
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304Association between glomerular filtration rate and endothelial function in an elderly community cohort
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305Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
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306Clinical and Genetic Correlates of Growth Differentiation Factor 15 in the Community
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307FTO genotype is associated with phenotypic variability of body mass index
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308Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
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309Associations of Variants in FTO and Near MC4R With Obesity Traits in South Asian Indians
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310Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease6.1107Citations (PDF)
311A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans
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312A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
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313Relations of Circulating Resistin and Adiponectin and Cardiac Structure and Function: The Framingham Offspring Study
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314Genome-wide and gene-based association implicates FRMD6 in alzheimer disease
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315Large-scale association analysis identifies new risk loci for coronary artery disease
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316Assigning precursor–product ion relationships in indiscriminant MS/MS data from non-targeted metabolite profiling studies
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317Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
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318Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
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319Biomarkers of Extracellular Matrix Metabolism (MMP-9 and TIMP-1) and Risk of Stroke, Myocardial Infarction, and Cause-Specific Mortality: Cohort Study
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320Genomic inflation factors under polygenic inheritance3.0535Citations (PDF)
321CUBN Is a Gene Locus for Albuminuria0.4217Citations (PDF)
322Birth Characteristics and Subsequent Risks of Maternal Cardiovascular Disease
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323Identification of cis - and trans -Acting Genetic Variants Explaining Up to Half the Variation in Circulating Vascular Endothelial Growth Factor Levels
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324A Detailed Cardiovascular Characterization of Obesity Without the Metabolic Syndrome6.048Citations (PDF)
325Nationwide Cohort Study of Risk of Ischemic Heart Disease in Patients With Celiac Disease
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326Hysterectomy and risk of cardiovascular disease: a population-based cohort study
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327The combined contribution of albuminuria and glomerular filtration rate to the prediction of cardiovascular mortality in elderly men0.844Citations (PDF)
328Impact of BMI and the Metabolic Syndrome on the Risk of Diabetes in Middle-Aged Men
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329Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant
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330Association Between Serum Cathepsin S and Mortality in Older Adults16.672Citations (PDF)
331Biological, clinical and population relevance of 95 loci for blood lipids
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332Hundreds of variants clustered in genomic loci and biological pathways affect human height
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333Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
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334Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
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335Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
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336Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
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337Conjoint Effects of Serum Calcium and Phosphate on Risk of Total, Cardiovascular, and Noncardiovascular Mortality in the Community6.0130Citations (PDF)
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340Response to Letters Regarding Article, “The Impact of Body Mass Index and the Metabolic Syndrome on the Risk of Cardiovascular Disease and Death in Middle-Aged Men”
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341Impact of Body Mass Index and the Metabolic Syndrome on the Risk of Cardiovascular Disease and Death in Middle-Aged Men
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342Serum Cathepsin S Is Associated with Serum C-Reactive Protein and Interleukin-6 Independently of Obesity in Elderly Men4.137Citations (PDF)
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346Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden
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353Circulating Retinol-Binding Protein 4 and Subclinical Cardiovascular Disease in the Elderly
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356Circulating retinol-binding protein 4, cardiovascular risk factors and prevalent cardiovascular disease in elderly
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361Use of Multiple Biomarkers to Improve the Prediction of Death from Cardiovascular Causes
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0
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