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228 peer-reviewed articles • 19,671 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1S-Adenosylmethionine: A Multifaceted Regulator in Cancer Pathogenesis and Therapy
Cancers, 2025, 17, 535
2.722Citations (PDF)
2Fructose-induced progression of steatohepatitis involves disrupting aldolase B-AMPK signaling in methionine adenosyltransferase 1A deficient mice8.94Citations (PDF)
3S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury4.03Citations (PDF)
4Hepatic prohibitin 1 and methionine adenosyltransferase α1 defend against primary and secondary liver cancer metastasis
Journal of Hepatology, 2024, 80, 443-453
6.718Citations (PDF)
5The role of forkhead box M1-methionine adenosyltransferase 2 A/2B axis in liver inflammation and fibrosis10.811Citations (PDF)
6S‐adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells
Hepatology, 2022, 75, 280-296
9.628Citations (PDF)
7Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease10.839Citations (PDF)
8Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles
Hepatology, 2022, 76, 1121-1134
9.665Citations (PDF)
9Nonalcoholic fatty liver disease prevalence and severity in Asian Americans from the national health and nutrition examination surveys 2017–2018
Hepatology Communications, 2022, 6, 2253-2261
3.329Citations (PDF)
10TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis10.827Citations (PDF)
11Deletion of adipocyte prohibitin 1 exacerbates high‐fat diet‐induced steatosis but not liver inflammation and fibrosis
Hepatology Communications, 2022, 6, 3335-3348
3.32Citations (PDF)
12One Carbon Metabolism and S-Adenosylmethionine in Non-Alcoholic Fatty Liver Disease Pathogenesis and Subtypes
Livers, 2022, 2, 243-257
1.417Citations (PDF)
13Metabolic Landscape of the Mouse Liver by Quantitative 31P Nuclear Magnetic Resonance Analysis of the Phosphorome
Hepatology, 2021, 74, 148-163
9.628Citations (PDF)
14Detection of Circulating Tumor Cells and Their Implications as a Biomarker for Diagnosis, Prognostication, and Therapeutic Monitoring in Hepatocellular Carcinoma
Hepatology, 2021, 73, 422-436
9.6316Citations (PDF)
15Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity6.625Citations (PDF)
16Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
JHEP Reports, 2021, 3, 100276
3.113Citations (PDF)
17State‐Level HCC Incidence and Association With Obesity and Physical Activity in the United States
Hepatology, 2021, 74, 1384-1394
9.635Citations (PDF)
18The Mortality and Overall Survival Trends of Primary Liver Cancer in the United States3.2107Citations (PDF)
19A molecular signature for the metabolic syndrome by urine metabolomics8.141Citations (PDF)
20Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans
Oncogene, 2021, 40, 5866-5879
5.214Citations (PDF)
21Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-225.232Citations (PDF)
22Incidence of Pancreatic Cancer by Age and Sex in the US, 2000-201814.4135Citations (PDF)
23SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum
IScience, 2020, 23, 101645
2.4217Citations (PDF)
24Lysine and Arginine Protein Post-translational Modifications by Enhanced DIA Libraries: Quantification in Murine Liver Disease
Journal of Proteome Research, 2020, 19, 4163-4178
2.228Citations (PDF)
25NASH is the leading indication for liver transplantation in elderly patients
Journal of Hepatology, 2020, 73, S266
6.70Citations (PDF)
26PINE: An Automation Tool to Extract and Visualize Protein-Centric Functional Networks1.836Citations (PDF)
27Chemotherapy-associated liver injury in colorectal cancer2.048Citations (PDF)
28Dysregulation of glutathione synthesis in liver disease
Liver Research, 2020, 4, 64-73
2.081Citations (PDF)
29Reciprocal Regulation Between Forkhead Box M1/NF‐κB and Methionine Adenosyltransferase 1A Drives Liver Cancer
Hepatology, 2020, 72, 1682-1700
9.643Citations (PDF)
30Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
Cell Metabolism, 2020, 31, 605-622.e10
20.8143Citations (PDF)
31Prohibitin 1 in liver injury and cancer2.133Citations (PDF)
32Increase in Alcoholic Hepatitis as an Etiology for Liver Transplantation in the United States: A 2004–2018 Analysis
Transplantation Direct, 2020, 6, e612
1.37Citations (PDF)
33The Prolyl Isomerase PIN1 Impairs Methionine Adenosyltransferase α1 Mitochondrial Targeting in Alcoholic Liver Disease
FASEB Journal, 2020, 34, 1-1
2.30Citations (PDF)
34miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, 2019, 29, 40-54
3.651Citations (PDF)
35Current status of hepatocellular carcinoma detection: screening strategies and novel biomarkers2.183Citations (PDF)
36Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis8.7158Citations (PDF)
37Methionine Adenosyltransferase α1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression
Hepatology, 2019, 70, 2018-2034
9.637Citations (PDF)
38NOD‐like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD
Hepatology, 2019, 70, 1582-1599
9.6110Citations (PDF)
39The mitochondrial chaperone Prohibitin 1 negatively regulates interleukin-8 in human liver cancers
Journal of Biological Chemistry, 2019, 294, 1984-1996
1.319Citations (PDF)
40Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy2.181Citations (PDF)
41Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells
Hepatology Communications, 2018, 2, 1583-1600
3.318Citations (PDF)
42MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis6.646Citations (PDF)
43Liver cancer-associated changes to the proteome: what deserves clinical focus?
Expert Review of Proteomics, 2018, 15, 749-756
1.610Citations (PDF)
44Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer
Gastroenterology, 2018, 155, 557-571.e14
0.995Citations (PDF)
45Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts
Hepatology Communications, 2018, 2, 807-820
3.3151Citations (PDF)
46NASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances0.7542Citations (PDF)
47Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
Gastroenterology, 2017, 152, 1449-1461.e7
0.9258Citations (PDF)
48Coffee Drinking and Alcoholic and Nonalcoholic Fatty Liver Diseases and Viral Hepatitis in the Multiethnic Cohort5.025Citations (PDF)
49Prohibitin 1 suppresses liver cancer tumorigenesis in mice and human hepatocellular and cholangiocarcinoma cells
Hepatology, 2017, 65, 1249-1266
9.657Citations (PDF)
50Role of aramchol in steatohepatitis and fibrosis in mice
Hepatology Communications, 2017, 1, 911-927
3.3114Citations (PDF)
51Methionine adenosyltransferases in liver health and diseases
Liver Research, 2017, 1, 103-111
2.058Citations (PDF)
52Deregulated neddylation in liver fibrosis
Hepatology, 2017, 65, 694-709
9.681Citations (PDF)
53The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury10.8109Citations (PDF)
54A morphological method for ammonia detection in liver
PLoS ONE, 2017, 12, e0173914
1.539Citations (PDF)
55Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort
Hepatology, 2016, 64, 1969-1977
9.6275Citations (PDF)
56Deregulated methionine adenosyltransferase α1, c‐Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans‡
Hepatology, 2016, 64, 439-455
9.653Citations (PDF)
57MicroRNA-mediated regulation of glutathione and methionine metabolism and its relevance for liver disease2.645Citations (PDF)
58Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes
Journal of Biological Chemistry, 2016, 291, 24148-24159
1.320Citations (PDF)
59Disparity in liver cancer incidence and chronic liver disease mortality by nativity in Hispanics: The Multiethnic Cohort
Cancer, 2016, 122, 1444-1452
2.752Citations (PDF)
60Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes5.250Citations (PDF)
61Sex and Ethnic Differences in the Association of Obesity With Risk of Hepatocellular Carcinoma5.048Citations (PDF)
62Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis
Journal of Hepatology, 2016, 64, 409-418
6.771Citations (PDF)
63Histone deacetylase 4 promotes cholestatic liver injury in the absence of prohibitin‐1
Hepatology, 2015, 62, 1237-1248
9.636Citations (PDF)
64Silencing of human methionine adenosyltransferase 1A expression by methylation of the coding region.1.31Citations (PDF)
65Activation of a Novel c-Myc-miR27-Prohibitin 1 Circuitry in Cholestatic Liver Injury Inhibits Glutathione Synthesis in Mice4.161Citations (PDF)
66S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease
Journal of Hepatology, 2015, 62, 673-681
6.759Citations (PDF)
67Methionine Adenosyltransferase 2B–GIT1 Complex Serves as a Scaffold to Regulate Ras/Raf/MEK1/2 Activity in Human Liver and Colon Cancer Cells
American Journal of Pathology, 2015, 185, 1135-1144
2.841Citations (PDF)
68Nonalcoholic fatty liver disease: Update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine2.1104Citations (PDF)
69S-Adenosylmethionine and Methylthioadenosine Inhibit β-Catenin Signaling by Multiple Mechanisms in Liver and Colon Cancer
Molecular Pharmacology, 2015, 87, 77-86
2.427Citations (PDF)
70Association of Coffee Intake With Reduced Incidence of Liver Cancer and Death From Chronic Liver Disease in the US Multiethnic Cohort
Gastroenterology, 2015, 148, 118-125
0.9171Citations (PDF)
71Diabetes and Racial/Ethnic Differences in Hepatocellular Carcinoma Risk: The Multiethnic Cohort3.248Citations (PDF)
72Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity
Journal of Proteomics, 2014, 103, 227-240
1.974Citations (PDF)
73Systems biology for hepatologists
Hepatology, 2014, 60, 736-743
9.616Citations (PDF)
74Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice2.634Citations (PDF)
75GlycineN‐methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance
Hippocampus, 2014, 24, 840-852
1.733Citations (PDF)
76S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome
Neuron, 2014, 81, 1024-1039
8.278Citations (PDF)
77Structure and function study of the complex that synthesizesS-adenosylmethionine
IUCrJ, 2014, 1, 240-249
1.953Citations (PDF)
78TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency
Laboratory Investigation, 2014, 95, 223-236
1.832Citations (PDF)
79Glutathione synthesis1.62,018Citations (PDF)
80MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer
Hepatology, 2013, 57, 2299-2313
9.678Citations (PDF)
81Polyamine and methionine adenosyltransferase 2A crosstalk in human colon and liver cancer
Experimental Cell Research, 2013, 319, 1902-1911
2.147Citations (PDF)
82Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis
Hepatology, 2013, 58, 1296-1305
9.6121Citations (PDF)
83Methionine Adenosyltransferase 2B, HuR, and Sirtuin 1 Protein Cross-talk Impacts on the Effect of Resveratrol on Apoptosis and Growth in Liver Cancer Cells
Journal of Biological Chemistry, 2013, 288, 23161-23170
1.345Citations (PDF)
84S-adenosylmethionine metabolism and liver disease
Annals of Hepatology, 2013, 12, 183-189
1.2203Citations (PDF)
85MicroRNAs regulate methionine adenosyltransferase 1A expression in hepatocellular carcinoma6.6138Citations (PDF)
86Effects of S -adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice
Carcinogenesis, 2012, 33, 427-435
2.277Citations (PDF)
87Mechanism and Significance of Changes in Glutamate-Cysteine Ligase Expression during Hepatic Fibrogenesis
Journal of Biological Chemistry, 2012, 287, 36341-36355
1.352Citations (PDF)
88S-adenosylmethionine in Liver Health, Injury, and Cancer
Physiological Reviews, 2012, 92, 1515-1542
20.1553Citations (PDF)
89Human antigen R contributes to hepatic stellate cell activation and liver fibrosis
Hepatology, 2012, 56, 1870-1882
9.685Citations (PDF)
90The RNA-Binding Protein Human Antigen R Controls Global Changes in Gene Expression during Schwann Cell Development
Journal of Neuroscience, 2012, 32, 4944-4958
2.314Citations (PDF)
91Hepatoma Cells From Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1
Gastroenterology, 2012, 143, 787-798.e13
0.947Citations (PDF)
92Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation
Hepatology, 2012, 55, 1237-1248
9.6130Citations (PDF)
93Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase
Hepatology, 2012, 56, 747-759
9.660Citations (PDF)
94S -adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers
Hepatology, 2012, 56, 982-993
9.678Citations (PDF)
95Proteomic analysis of human hepatoma cells expressing methionine adenosyltransferase I/III
Journal of Proteomics, 2012, 75, 2855-2868
1.911Citations (PDF)
96Inhibition of human methionine adenosyltransferase 1A transcription by coding region methylation
Journal of Cellular Physiology, 2012, 227, 1583-1591
2.531Citations (PDF)
97Methionine Adenosyltransferase 2A Positively Regulates Bcl‐2 Expression in a Ubiquitin‐Conjugating Enzyme 9‐Dependent Manner
FASEB Journal, 2012, 26,
2.30Citations (PDF)
98Role of AMP-activated protein kinase in the control of hepatocyte priming and proliferation during liver regeneration2.124Citations (PDF)
99Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells
Biochemical Journal, 2011, 436, 507-516
2.333Citations (PDF)
100The Hepatocarcinogenic Effect of Methionine and Choline Deficient Diets: An Adaptation to the Warburg Effect?0.515Citations (PDF)
101S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes2.612Citations (PDF)
102Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in mice
Hepatology, 2011, 54, 1975-1986
9.691Citations (PDF)
103High-Frequency Ultrasound Imaging for Longitudinal Evaluation of Non-Alcoholic Fatty Liver Disease Progression in Mice1.718Citations (PDF)
104Role of Methionine Adenosyltransferase Genes in Hepatocarcinogenesis
Cancers, 2011, 3, 1480-1497
2.741Citations (PDF)
105Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity
Metabolomics, 2011, 8, 997-1011
1.970Citations (PDF)
106Changes in the Expression of Methionine Adenosyltransferase Genes and S-Adenosylmethionine Homeostasis During Hepatic Stellate Cell Activation
Hepatology, 2010, 51, 986-995
9.658Citations (PDF)
107The role of stem cells/progenitor cells in liver carcinogenesis in glycine N-methyltransferase deficient mice2.513Citations (PDF)
108The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats2.520Citations (PDF)
109Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice†
Hepatology, 2010, 51, 1291-1301
9.633Citations (PDF)
110S -Adenosylmethionine Regulates Dual-Specificity Mitogen-Activated Protein Kinase Phosphatase Expression in Mouse and Human Hepatocytes
Hepatology, 2010, 51, 2152-2161
9.640Citations (PDF)
111Fatty Liver and Fibrosis in Glycine N -Methyltransferase Knockout Mice Is Prevented by Nicotinamide
Hepatology, 2010, 52, 105-114
9.699Citations (PDF)
112Epithelial-to-Mesenchymal Transition of Murine Liver Tumor Cells Promotes Invasion†,‡
Hepatology, 2010, 52, 945-953
9.6147Citations (PDF)
113Activation of LKB1-Akt Pathway Independent of Phosphoinositide 3-Kinase Plays a Critical Role in the Proliferation of Hepatocellular Carcinoma From Nonalcoholic Steatohepatitis
Hepatology, 2010, 52, 1621-1631
9.667Citations (PDF)
114Liver-Specific Deletion of Prohibitin 1 Results in Spontaneous Liver Injury, Fibrosis, and Hepatocellular Carcinoma in Mice
Hepatology, 2010, 52, 2096-2108
9.6112Citations (PDF)
115Candidate biomarkers in exosome‐like vesicles purified from rat and mouse urine samples1.5126Citations (PDF)
116Non‐alcoholic fatty liver disease proteomics1.556Citations (PDF)
117Sub‐proteome approach to the knowledge of liver1.59Citations (PDF)
118Novel Function and Intracellular Localization of Methionine Adenosyltransferase 2β Splicing Variants
Journal of Biological Chemistry, 2010, 285, 20015-20021
1.332Citations (PDF)
119Liquid Chromatography−Mass Spectrometry-Based Parallel Metabolic Profiling of Human and Mouse Model Serum Reveals Putative Biomarkers Associated with the Progression of Nonalcoholic Fatty Liver Disease
Journal of Proteome Research, 2010, 9, 4501-4512
2.2154Citations (PDF)
120HuR/Methyl-HuR and AUF1 Regulate the MAT Expressed During Liver Proliferation, Differentiation, and Carcinogenesis
Gastroenterology, 2010, 138, 1943-1953.e3
0.9127Citations (PDF)
121Forced Expression of Methionine Adenosyltransferase 1A in Human Hepatoma Cells Suppresses in Vivo Tumorigenicity in Mice
American Journal of Pathology, 2010, 176, 2456-2466
2.844Citations (PDF)
122S-Adenosylmethionine and Methylthioadenosine Inhibit Cellular FLICE Inhibitory Protein Expression and Induce Apoptosis in Colon Cancer Cells
Molecular Pharmacology, 2009, 76, 192-200
2.457Citations (PDF)
123Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms2.540Citations (PDF)
124Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation #
Hepatology, 2009, 49, 608-617
9.672Citations (PDF)
125Switch from Mnt‐Max to Myc‐Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes†
Hepatology, 2009, 49, 860-870
9.647Citations (PDF)
126CD133+ liver cancer stem cells from methionine adenosyl transferase 1A–deficient mice demonstrate resistance to transforming growth factor (TGF)-β–induced apoptosis #
Hepatology, 2009, 49, 1277-1286
9.690Citations (PDF)
127Dysregulation of glutathione synthesis during cholestasis in mice
Hepatology, 2009, 49, 1982-1991
9.684Citations (PDF)
128S‐adenosylmethionine in the chemoprevention and treatment of hepatocellular carcinoma in a rat model†
Hepatology, 2009, 50, 462-471
9.686Citations (PDF)
129Impaired liver regeneration in mice lacking glycine N‐methyltransferase†
Hepatology, 2009, 50, 443-452
9.639Citations (PDF)
130Identification and characterization of an Nrf2‐mediated ARE upstream of the rat glutamate cysteine ligase catalytic subunit gene (GCLC)1.837Citations (PDF)
131Non-alcoholic steatohepatitis and animal models: Understanding the human disease1.9105Citations (PDF)
132Regulation of glutathione synthesis7.51,942Citations (PDF)
133S-Adenosylmethionine Regulates Apurinic/Apyrimidinic Endonuclease 1 Stability: Implication in Hepatocarcinogenesis
Gastroenterology, 2009, 136, 1025-1036
0.934Citations (PDF)
134Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2β
Hepatology, 2008, 47, 521-531
9.682Citations (PDF)
135Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A–deficient mice†
Hepatology, 2008, 47, 1288-1297
9.689Citations (PDF)
136Loss of the glycine N‐methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice†
Hepatology, 2008, 47, 1191-1199
9.6299Citations (PDF)
137S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation
Hepatology, 2008, 47, 1655-1666
9.6107Citations (PDF)
138Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice
Laboratory Investigation, 2008, 88, 1121-1129
1.853Citations (PDF)
139Emerging Role of Epigenetics in the Actions of Alcohol0.5194Citations (PDF)
140S‐Adenosylmethionine in cell growth, apoptosis and liver cancer1.8182Citations (PDF)
141Alcohol, cofactors and the genetics of hepatocellular carcinoma1.852Citations (PDF)
142Effects of hepatocyte growth factor on glutathione synthesis, growth, and apoptosis is cell density-dependent
Experimental Cell Research, 2008, 314, 398-412
2.119Citations (PDF)
143Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes
Journal of Proteome Research, 2008, 7, 5157-5166
2.2600Citations (PDF)
144Expression Pattern, Regulation, and Functions of Methionine Adenosyltransferase 2β Splicing Variants in Hepatoma Cells
Gastroenterology, 2008, 134, 281-291
0.973Citations (PDF)
145Methionine Metabolism and Liver Disease
Annual Review of Nutrition, 2008, 28, 273-293
6.4285Citations (PDF)
146Epigallocatechin-3-gallate Inhibits Growth of Activated Hepatic Stellate Cells by Enhancing the Capacity of Glutathione Synthesis
Molecular Pharmacology, 2008, 73, 1465-1473
2.443Citations (PDF)
147Requirement of RIZ1 for cancer prevention by methyl-balanced diet0.00Citations (PDF)
148Requirement of RIZ1 for Cancer Prevention by Methyl-Balanced Diet
PLoS ONE, 2008, 3, e3390
1.526Citations (PDF)
149Inhibition of human betaine–homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine
Biochemical Journal, 2007, 401, 87-96
2.372Citations (PDF)
150Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium3.2208Citations (PDF)
151Identification of a gene-pathway associated with non-alcoholic steatohepatitis
Journal of Hepatology, 2007, 46, 708-718
6.753Citations (PDF)
152Role of Methionine Adenosyltransferase 2A and S-adenosylmethionine in Mitogen-Induced Growth of Human Colon Cancer Cells
Gastroenterology, 2007, 133, 207-218
0.9109Citations (PDF)
153Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells
Journal of Cellular Physiology, 2007, 210, 766-773
2.526Citations (PDF)
154Role of S-adenosyl-L-methionine in liver health and injury
Hepatology, 2007, 45, 1306-1312
9.6285Citations (PDF)
155Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma
Hepatology, 2007, 46, 749-758
9.677Citations (PDF)
156Molecular Profiling of Hepatocellular Carcinoma in Mice with a Chronic Deficiency of HepaticS-Adenosylmethionine:  Relevance in Human Liver Diseases2.218Citations (PDF)
157S–Adenosylmethionine Regulates Cytoplasmic HuR Via AMP–Activated Kinase
Gastroenterology, 2006, 131, 223-232
0.995Citations (PDF)
158Methionine adenosyltransferase and S-adenosylmethionine in alcoholic liver disease1.827Citations (PDF)
159S -adenosylmethionine stabilizes cystathionine β-synthase and modulates redox capacity5.2230Citations (PDF)
160Tumour necrosis factor α induces co-ordinated activation of rat GSH synthetic enzymes via nuclear factor κB and activator protein-1
Biochemical Journal, 2005, 391, 399-408
2.376Citations (PDF)
161Cloning and characterization of the human glutathione synthetase 5′-flanking region
Biochemical Journal, 2005, 390, 521-528
2.373Citations (PDF)
162Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer
Alcohol, 2005, 35, 227-234
0.7145Citations (PDF)
163Keratin mutation primes mouse liver to oxidative injury
Hepatology, 2005, 41, 517-525
9.639Citations (PDF)
164Oxidation of specific methionine and tryptophan residues of apolipoprotein A-I in hepatocarcinogenesis
Proteomics, 2005, 5, 4964-4972
2.131Citations (PDF)
165Nrf1 and Nrf2 Regulate Rat Glutamate-Cysteine Ligase Catalytic Subunit Transcription Indirectly via NF-κB and AP-1
Molecular and Cellular Biology, 2005, 25, 5933-5946
1.5251Citations (PDF)
166Increased susceptibility of glutathione peroxidase-1 transgenic mice to kainic acid-related seizure activity and hippocampal neuronal cell death
Experimental Neurology, 2005, 192, 203-214
2.918Citations (PDF)
167Silencing of human methionine adenosyltransferase 1A expression by methylation of the coding region1.34Citations (PDF)
16815-Deoxy-Δ12,14-Prostaglandin J2 Protects against Nitrosative PC12 Cell Death through Up-regulation of Intracellular Glutathione Synthesis
Journal of Biological Chemistry, 2004, 279, 46263-46270
1.350Citations (PDF)
169Retinoid X Receptor α Regulates Glutathione Homeostasis and Xenobiotic Detoxification Processes in Mouse Liver
Molecular Pharmacology, 2004, 65, 550-557
2.471Citations (PDF)
170Inhibition of lipopolysaccharide-stimulated TNF-α promoter activity byS-adenosylmethionine and 5′-methylthioadenosine1.869Citations (PDF)
171Abnormal Hepatic Methionine and Glutathione Metabolism in Patients With Alcoholic Hepatitis0.5147Citations (PDF)
1725′-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes
Hepatology, 2004, 39, 1088-1098
9.6102Citations (PDF)
173S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-xS
Hepatology, 2004, 40, 221-231
9.683Citations (PDF)
174Methylthioadenosine1.9231Citations (PDF)
175RXRα-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity2.524Citations (PDF)
176Functional proteomics of nonalcoholic steatohepatitis: Mitochondrial proteins as targets of S -adenosylmethionine5.2160Citations (PDF)
177L-Methionine Availability Regulates Expression of the Methionine Adenosyltransferase 2A Gene in Human Hepatocarcinoma Cells
Journal of Biological Chemistry, 2003, 278, 19885-19890
1.379Citations (PDF)
178Induction of Human Methionine Adenosyltransferase 2A Expression by Tumor Necrosis Factor α
Journal of Biological Chemistry, 2003, 278, 50887-50896
1.354Citations (PDF)
179Role of S‐adenosylmethionine in two experimental models of pancreatitis
FASEB Journal, 2003, 17, 56-58
2.334Citations (PDF)
180S‐Adenosylmethionine: a control switch that regulates liver function
FASEB Journal, 2002, 16, 15-26
2.3410Citations (PDF)
181Role of AP-1 in the Coordinate Induction of Rat Glutamate-cysteine Ligase and Glutathione Synthetase bytert-Butylhydroquinone
Journal of Biological Chemistry, 2002, 277, 35232-35239
1.336Citations (PDF)
182Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
FASEB Journal, 2002, 16, 1292-1294
2.3275Citations (PDF)
183Role of abnormal methionine metabolism in alcoholic liver injury
Alcohol, 2002, 27, 155-162
0.792Citations (PDF)
184S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells
Hepatology, 2002, 35, 274-280
9.6129Citations (PDF)
185The role of c‐Myb and Sp1 in the up‐regulation of methionine adenosyltransferase 2A gene expression in human hepatocellular carcinoma
FASEB Journal, 2001, 15, 1507-1516
2.368Citations (PDF)
186Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation5.2441Citations (PDF)
187Current concepts in the pathogenesis of alcoholic liver injury
FASEB Journal, 2001, 15, 1335-1349
2.3352Citations (PDF)
188Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer1.856Citations (PDF)
189The role of c-Myb in the up-regulation of methionine adenosyltransferase 2A expression in activated Jurkat cells
Biochemical Journal, 2001, 353, 163-168
2.317Citations (PDF)
190Cloning and characterization of the 5′-flanking region of the rat glutamate-cysteine ligase catalytic subunit
Biochemical Journal, 2001, 357, 447-455
2.346Citations (PDF)
191Seroprevalence and Demographic Characteristics of HTLV-I Among Blood Donors in Taiwan: 1996–19990.917Citations (PDF)
192Cloning and functional characterization of the 5′-flanking region of human methionine adenosyltransferase 1A gene
Biochemical Journal, 2000, 346, 475-482
2.327Citations (PDF)
193Inducers of γ-glutamylcysteine synthetase and their effects on glutathione synthetase expression3.459Citations (PDF)
194Liver‐specific methionine adenosyltransferase MAT1A gene expression is associated with a specific pattern of promoter methylation and histone acetylation: implications for MAT1A silencing during transformation
FASEB Journal, 2000, 14, 95-102
2.393Citations (PDF)
195Changes in methionine adenosyltransferase andS-adenosylmethionine homeostasis in alcoholic rat liver1.8174Citations (PDF)
196S-Adenosylmethionine1.9484Citations (PDF)
197Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma
Journal of Hepatology, 2000, 33, 907-914
6.7337Citations (PDF)
198Regulation of hepatic glutathione synthesis: current concepts and controversies
FASEB Journal, 1999, 13, 1169-1183
2.3769Citations (PDF)
199Effect of Thioacetamide on the Hepatic Expression of γ-Glutamylcysteine Synthetase Subunits in the Rat2.257Citations (PDF)
200Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat
Hepatology, 1999, 29, 1471-1478
9.654Citations (PDF)
201Effect of ethanol and high-fat feeding on hepatic ?-glutamylcysteine synthetase subunit expression in the rat
Hepatology, 1999, 30, 209-214
9.668Citations (PDF)
202Changes in glutathione homeostasis during liver regeneration in the rat
Hepatology, 1998, 27, 147-153
9.689Citations (PDF)
203Cloning, sequencing and expression of a cDNA encoding bovine pancreatic deoxyribonuclease I in Escherichia coli: purification and characterization of the recombinant enzyme
Gene, 1998, 206, 181-184
1.627Citations (PDF)
204Cloning and Functional Characterization of the 5′-Flanking Region of Human Methionine Adenosyltransferase 2A Gene1.526Citations (PDF)
205Regulation of Hepatic Glutathione Synthesis
Seminars in Liver Disease, 1998, 18, 331-343
2.093Citations (PDF)
206Porcine Spleen Deoxyribonuclease II
Journal of Biological Chemistry, 1998, 273, 17192-17198
1.341Citations (PDF)
207Changes in methionine adenosyltransferase during liver regeneration in the rat1.863Citations (PDF)
208The Rana catesbeiana rcr Gene Encoding a Cytotoxic Ribonuclease
Journal of Biological Chemistry, 1998, 273, 6395-6401
1.345Citations (PDF)
209Differential regulation of γ-glutamylcysteine synthetase heavy and light subunit gene expression
Biochemical Journal, 1997, 326, 167-172
2.3122Citations (PDF)
210Progressive defect in biliary GSH secretion in streptozotocin-induced diabetic rats1.86Citations (PDF)
211Regulation of γ-glutamylcysteine synthetase by protein phosphorylation
Biochemical Journal, 1996, 320, 321-328
2.3104Citations (PDF)
212Changes in S-adenosylmethionine synthetase in human liver cancer: Molecular characterization and significance
Hepatology, 1996, 24, 1090-1097
9.67Citations (PDF)
213Role of two recently cloned rat liver GSH transporters in the ubiquitous transport of GSH in mammalian cells.6.647Citations (PDF)
214Inhibition of reduced glutathione synthesis by cyanobacterial alkaloid cylindrospermopsin in cultured rat hepatocytes
Biochemical Pharmacology, 1995, 49, 219-225
3.7246Citations (PDF)
215Hormonal and cell density regulation of hepatic gamma-glutamylcysteine synthetase gene expression.
Molecular Pharmacology, 1995, 48, 212-218
2.424Citations (PDF)
216The Role of Glutathione in the Toxicity of a Novel Cyanobacterial Alkaloid Cylindrospermopsin in Cultured Rat Hepatocytes1.5165Citations (PDF)
217Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes
Biochemical Pharmacology, 1994, 47, 859-869
3.746Citations (PDF)
218Specificity and directionality of thiol effects on sinusoidal glutathione transport in rat liver.
Molecular Pharmacology, 1994, 46, 578-585
2.47Citations (PDF)
219Restoration of gap-junctional intercellular communication in a communication-deficient rat liver cell mutant by transfection with connexin 43 cDNA
Molecular Carcinogenesis, 1993, 8, 234-244
2.127Citations (PDF)
220Bidirectional membrane transport of intact glutathione in Hep G2 cells1.88Citations (PDF)
221Thiol-disulfide effects on hepatic glutathione transport. Studies in cultured rat hepatocytes and perfused livers.6.627Citations (PDF)
222Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes2.967Citations (PDF)
223Insulin and glucocorticoid dependence of hepatic gamma-glutamylcysteine synthetase and glutathione synthesis in the rat. Studies in cultured hepatocytes and in vivo.6.693Citations (PDF)
224Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.6.688Citations (PDF)
225Hormonal regulation of glutathione efflux.
Journal of Biological Chemistry, 1990, 265, 16088-16095
1.392Citations (PDF)
226A novel role of secreted methionine adenosyltransferase α2 in colorectal liver metastases7.62Citations (PDF)
227Methionine Adenosyltransferase 1A and S-Adenosylmethionine in Alcohol-Associated Liver Disease
Antioxidants, 0, 14, 1486
4.63Citations (PDF)
228Loss of fungal sensing exacerbates liver injury in a murine model of MASLD
JCI Insight, 0, 11,
3.70Citations (PDF)