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400 peer-reviewed articles • 39,960 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism
EMBO Journal, 2025, 44, 1220-1248
5.117Citations (PDF)
2Molecular model of TFIIH recruitment to the transcription-coupled repair machinery10.810Citations (PDF)
3RNA sculpting by the primordial Helix-clasp-Helix–Strand-Loop (HcH–SL) motif enforces chemical recognition enabling diverse KH domain functions1.34Citations (PDF)
4BRCA2 C-terminal clamp restructures RAD51 dimers to bind B-DNA for replication fork stability
Molecular Cell, 2025, 85, 2080-2096.e6
8.613Citations (PDF)
5Information theory optimization of signals from small-angle scattering measurements
Biophysical Journal, 2025, 124, 2511-2522
1.52Citations (PDF)
6GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer10.835Citations (PDF)
7Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer10.84Citations (PDF)
8Chemical screening by time-resolved X-ray scattering to discover allosteric probes
Nature Chemical Biology, 2024, 20, 1199-1209
9.112Citations (PDF)
9A prismatic view of the epigenetic-metabolic regulatory axis in breast cancer therapy resistance
Oncogene, 2024, 43, 1727-1741
5.229Citations (PDF)
10Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation1.32Citations (PDF)
11Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair10.821Citations (PDF)
12A goldilocks computational protocol for inhibitor discovery targeting DNA damage responses including replication-repair functions2.43Citations (PDF)
13A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair
Nucleic Acids Research, 2023, 51, 1019-1033
10.732Citations (PDF)
14Epigenetic–Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer
Cancer Research, 2023, 83, 657-666
2.631Citations (PDF)
15Abstract 1394: Advanced computational modeling of molecular machines involved in transcription initiation and DNA repair1.30Citations (PDF)
16Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases10.826Citations (PDF)
17RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles10.838Citations (PDF)
18Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs5.826Citations (PDF)
19Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity
Nucleic Acids Research, 2023, 51, 9920-9937
10.730Citations (PDF)
20Stress Responses as Master Keys to Epigenomic Changes in Transcriptome and Metabolome for Cancer Etiology and Therapeutics1.52Citations (PDF)
21Distinct sequence features underlie microdeletions and gross deletions in the human genome
Human Mutation, 2022, 43, 328-346
1.06Citations (PDF)
22Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability
Microbial Cell, 2022, 9, 52-68
2.68Citations (PDF)
23Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
Cancer Discovery, 2022, 12, 1742-1759
6.8109Citations (PDF)
24Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair5.236Citations (PDF)
25Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease2.964Citations (PDF)
26Heparin-mediated dimerization of follistatin2.18Citations (PDF)
27Visualizing functional dynamicity in the DNA-dependent protein kinase holoenzyme DNA-PK complex by integrating SAXS with cryo-EM2.917Citations (PDF)
28Mechanism of efficient double-strand break repair by a long non-coding RNA
Nucleic Acids Research, 2021, 49, 1199-1200
10.731Citations (PDF)
29Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response2.934Citations (PDF)
30A collagen glucosyltransferase drives lung adenocarcinoma progression in mice3.127Citations (PDF)
31A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors
Nature Cancer, 2021, 2, 598-610
15.1320Citations (PDF)
32X‐ray scattering reveals disordered linkers and dynamic interfaces in complexes and mechanisms for DNA double‐strand break repair impacting cell and cancer biology
Protein Science, 2021, 30, 1735-1756
3.527Citations (PDF)
33Autism-Associated Vigilin Depletion Impairs DNA Damage Repair1.519Citations (PDF)
34EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart
Molecular Cell, 2021, 81, 2989-3006.e9
8.648Citations (PDF)
35GRB2 enforces homology-directed repair initiation by MRE11
Science Advances, 2021, 7,
8.136Citations (PDF)
36Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors2.957Citations (PDF)
37An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation2.927Citations (PDF)
38Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus1.314Citations (PDF)
39Target highlights in CASP14 : Analysis of models by structure providers1.939Citations (PDF)
40Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Nucleic Acids Research, 2021, 49, 221-243
10.743Citations (PDF)
41An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex
Nucleic Acids Research, 2021, 49, 306-321
10.733Citations (PDF)
42Aberrant RNA methylation triggers recruitment of an alkylation repair complex
Molecular Cell, 2021, 81, 4228-4242.e8
8.643Citations (PDF)
43Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites5.241Citations (PDF)
44Decoding Cancer Variants of Unknown Significance for Helicase–Nuclease–RPA Complexes Orchestrating DNA Repair During Transcription and Replication2.414Citations (PDF)
45Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy3.371Citations (PDF)
46Mechanism of efficient double-strand break repair by a long non-coding RNA
Nucleic Acids Research, 2020, 48, 10953-10972
10.753Citations (PDF)
47Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair
DNA Repair, 2020, 96, 102972
1.859Citations (PDF)
48Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development1.562Citations (PDF)
49XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
NAR Cancer, 2020, 2,
2.550Citations (PDF)
50PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Nature Cell Biology, 2020, 22, 1264-1275
12.6853Citations (PDF)
51Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations5.261Citations (PDF)
52Replication‐Based Rearrangements Are a Common Mechanism for SNCA Duplication in Parkinson's Disease
Movement Disorders, 2020, 35, 868-876
3.213Citations (PDF)
53Small angle X‐ray scattering‐assisted protein structure prediction in CASP13 and emergence of solution structure differences1.932Citations (PDF)
54Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis
Structure, 2019, 27, 1485-1496.e4
2.428Citations (PDF)
55SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair
Nucleic Acids Research, 2019, 47, 10181-10201
10.737Citations (PDF)
56Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology4.6186Citations (PDF)
57Transcription preinitiation complex structure and dynamics provide insight into genetic diseases5.884Citations (PDF)
58Cancer mutational burden is shaped by G4 DNA, replication stress and mitochondrial dysfunction2.952Citations (PDF)
59Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation5.252Citations (PDF)
60Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death10.8127Citations (PDF)
61The structure of the periplasmic FlaG–FlaF complex and its essential role for archaellar swimming motility
Nature Microbiology, 2019, 5, 216-225
9.948Citations (PDF)
62Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding10.849Citations (PDF)
63Small angle X‐ray scattering and cross‐linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy1.927Citations (PDF)
64The MRE11–RAD50–NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair14.0387Citations (PDF)
65Structural Control of Nonnative Ligand Binding in Engineered Mutants of Phosphoenolpyruvate Carboxykinase
Biochemistry, 2018, 57, 6688-6700
1.57Citations (PDF)
66Dissection of DNA double-strand-break repair using novel single-molecule forceps5.897Citations (PDF)
67Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex
Nucleic Acids Research, 2017, , gkw1262
10.769Citations (PDF)
68Structural and functional characterization of the PNKP–XRCC4–LigIV DNA repair complex
Nucleic Acids Research, 2017, 45, 6238-6251
10.753Citations (PDF)
69Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome
Structure, 2017, 25, 157-166
2.425Citations (PDF)
70Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability10.8115Citations (PDF)
71Charging of Proteins in Native Mass Spectrometry1.847Citations (PDF)
722017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update2.8269Citations (PDF)
73The nucleotide‐dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor
Molecular Microbiology, 2016, 99, 674-685
1.858Citations (PDF)
74Designing and defining dynamic protein cage nanoassemblies in solution
Science Advances, 2016, 2,
8.145Citations (PDF)
75Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences
Nucleic Acids Research, 2016, 44, 5673-5688
10.7165Citations (PDF)
76FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles
Nucleic Acids Research, 2016, 44, W424-W429
10.7565Citations (PDF)
77An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex
Journal of Biological Chemistry, 2016, 291, 26987-27006
1.372Citations (PDF)
78HU multimerization shift controls nucleoid compaction
Science Advances, 2016, 2,
8.1186Citations (PDF)
79Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN
Molecular Cell, 2016, 64, 688-703
8.6240Citations (PDF)
80Defining NADH-Driven Allostery Regulating Apoptosis-Inducing Factor
Structure, 2016, 24, 2067-2079
2.456Citations (PDF)
81RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment
Journal of Biological Chemistry, 2016, 291, 9396-9410
1.338Citations (PDF)
82Perchlorate Reductase Is Distinguished by Active Site Aromatic Gate Residues
Journal of Biological Chemistry, 2016, 291, 9190-9202
1.395Citations (PDF)
83Cell-free expression of functional receptor tyrosine kinases2.731Citations (PDF)
84Modeling Macromolecular Motions by X-Ray-Scattering-Constrained Molecular Dynamics
Biophysical Journal, 2015, 108, 2421-2423
1.57Citations (PDF)
85FlaF Is a β-Sandwich Protein that Anchors the Archaellum in the Archaeal Cell Envelope by Binding the S-Layer Protein
Structure, 2015, 23, 863-872
2.471Citations (PDF)
86Structurally Distinct Ubiquitin- and Sumo-Modified PCNA: Implications for Their Distinct Roles in the DNA Damage Response
Structure, 2015, 23, 724-733
2.444Citations (PDF)
87Exploring the repeat protein universe through computational protein design
Nature, 2015, 528, 580-584
30.6283Citations (PDF)
88Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining
Nucleic Acids Research, 2015, 43, 7021-7031
10.729Citations (PDF)
89Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair2.9108Citations (PDF)
90Emerging critical roles of Fe–S clusters in DNA replication and repair2.5231Citations (PDF)
91Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus
Journal of Bacteriology, 2015, 197, 3834-3847
2.228Citations (PDF)
92Archaeal Genome Guardians Give Insights into Eukaryotic DNA Replication and Damage Response Proteins
Archaea, 2014, 2014, 1-24
0.018Citations (PDF)
93A structure-specific nucleic acid-binding domain conserved among DNA repair proteins5.245Citations (PDF)
94The Rad50 hook domain regulates DNA damage signaling and tumorigenesis
Genes and Development, 2014, 28, 451-462
2.851Citations (PDF)
95The R‐factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures
FEBS Journal, 2014, 281, 4046-4060
3.3103Citations (PDF)
96Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing
Nucleic Acids Research, 2014, 42, 906-917
10.761Citations (PDF)
97ModBase, a database of annotated comparative protein structure models and associated resources
Nucleic Acids Research, 2014, 42, D336-D346
10.7309Citations (PDF)
98The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once
DNA Repair, 2014, 19, 95-107
1.889Citations (PDF)
99DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Molecular Cell, 2014, 53, 7-18
8.6548Citations (PDF)
100Structure of a designed protein cage that self-assembles into a highly porous cube
Nature Chemistry, 2014, 6, 1065-1071
15.5302Citations (PDF)
101Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes5.278Citations (PDF)
102Intact Functional Fourteen-subunit Respiratory Membrane-bound [NiFe]-Hydrogenase Complex of the Hyperthermophilic Archaeon Pyrococcus furiosus
Journal of Biological Chemistry, 2014, 289, 19364-19372
1.341Citations (PDF)
103How substrate specificity is imposed on a histone demethylase—lessons from KDM2A
Genes and Development, 2014, 28, 1735-1738
2.815Citations (PDF)
104Interfacial Residues Promote an Optimal Alignment of the Catalytic Center in Human Soluble Guanylate Cyclase: Heterodimerization Is Required but Not Sufficient for Activity
Biochemistry, 2014, 53, 2153-2165
1.541Citations (PDF)
105Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time
DNA Repair, 2014, 17, 110-120
1.8105Citations (PDF)
106RNF 4 interacts with both SUMO and nucleosomes to promote the DNA damage response
EMBO Reports, 2014, 15, 601-608
3.549Citations (PDF)
107Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments
Biophysical Journal, 2013, 105, 962-974
1.5597Citations (PDF)
108Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source1.7253Citations (PDF)
109Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2
Structure, 2013, 21, 154-166
2.49Citations (PDF)
110The Disordered C-Terminal Domain of Human DNA Glycosylase NEIL1 Contributes to Its Stability via Intramolecular Interactions
Journal of Molecular Biology, 2013, 425, 2359-2371
2.945Citations (PDF)
111Insights into FlaI Functions in Archaeal Motor Assembly and Motility from Structures, Conformations, and Genetics
Molecular Cell, 2013, 49, 1069-1082
8.6113Citations (PDF)
112XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair1.5104Citations (PDF)
113Accurate assessment of mass, models and resolution by small-angle scattering
Nature, 2013, 496, 477-481
30.6770Citations (PDF)
114Report of the wwPDB Small-Angle Scattering Task Force: Data Requirements for Biomolecular Modeling and the PDB
Structure, 2013, 21, 875-881
2.483Citations (PDF)
115Developing advanced X-ray scattering methods combined with crystallography and computation
Methods, 2013, 59, 363-371
2.022Citations (PDF)
116Super-Resolution in Solution X-Ray Scattering and Its Applications to Structural Systems Biology
Annual Review of Biophysics, 2013, 42, 415-441
7.4184Citations (PDF)
117A new structural framework for integrating replication protein A into DNA processing machinery
Nucleic Acids Research, 2013, 41, 2313-2327
10.797Citations (PDF)
118Structural insights into the interaction of IL-33 with its receptors5.2198Citations (PDF)
119Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes
Journal of Biological Chemistry, 2013, 288, 8445-8455
1.3109Citations (PDF)
120Comprehensive macromolecular conformations mapped by quantitative SAXS analyses
Nature Methods, 2013, 10, 453-454
13.1129Citations (PDF)
121A Mutation in the FHA Domain ofCoprinus cinereusNbs1 Leads to Spo11-Independent Meiotic Recombination and Chromosome Segregation
G3: Genes, Genomes, Genetics, 2013, 3, 1927-1943
1.429Citations (PDF)
122DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals5.254Citations (PDF)
123Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends
Nucleic Acids Research, 2012, 40, 4507-4519
10.745Citations (PDF)
124Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
Nucleic Acids Research, 2012, 40, 11435-11449
10.720Citations (PDF)
125Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element5.864Citations (PDF)
126Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
Molecular Pharmacology, 2012, 82, 614-622
2.464Citations (PDF)
127Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase
Nucleic Acids Research, 2012, 40, 6070-6081
10.729Citations (PDF)
128MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA
Biology Open, 2012, 1, 863-873
0.763Citations (PDF)
129Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability5.249Citations (PDF)
130Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation–π interactions5.222Citations (PDF)
131Structure of an Essential Type IV Pilus Biogenesis Protein Provides Insights into Pilus and Type II Secretion Systems
Journal of Molecular Biology, 2012, 419, 110-124
2.929Citations (PDF)
132Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-Alkylguanines
Molecular Cell, 2012, 47, 50-60
8.635Citations (PDF)
133Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp25.859Citations (PDF)
134DNA charge transport as a first step in coordinating the detection of lesions by repair proteins5.2106Citations (PDF)
135Kinetic and Stoichiometric Characterisation of Streptavidin‐Binding Aptamers
ChemBioChem, 2012, 13, 829-836
1.927Citations (PDF)
136Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability
Journal of Biological Chemistry, 2012, 287, 22295-22304
1.3159Citations (PDF)
137Metals in biology: defining metalloproteomes4.794Citations (PDF)
138Double strand binding–single strand incision mechanism for human flap endonuclease: Implications for the superfamily3.819Citations (PDF)
139Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases5.865Citations (PDF)
140ATP-Stimulated, DNA-Mediated Redox Signaling by XPD, a DNA Repair and Transcription Helicase11.759Citations (PDF)
141Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily
Cell, 2011, 145, 198-211
23.4285Citations (PDF)
142The Structure of the CRISPR-Associated Protein Csa3 Provides Insight into the Regulation of the CRISPR/Cas System
Journal of Molecular Biology, 2011, 405, 939-955
2.990Citations (PDF)
143SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability
PLoS Genetics, 2011, 7, e1001320
2.248Citations (PDF)
144Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding
Biochemical Journal, 2011, 437, 43-52
2.364Citations (PDF)
145ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair5.8157Citations (PDF)
146P53 conformational switching for selectivity may reveal a general solution for specific DNA binding
EMBO Journal, 2011, 30, 2099-2100
5.15Citations (PDF)
147A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
BMC Bioinformatics, 2011, 12,
2.520Citations (PDF)
148XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase
DNA Repair, 2011, 10, 697-713
1.8154Citations (PDF)
149Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod‐Debye law
Biopolymers, 2011, 95, 559-571
1.5516Citations (PDF)
150Mapping interactions between the RNA chaperone FinO and its RNA targets
Nucleic Acids Research, 2011, 39, 4450-4463
10.743Citations (PDF)
151Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA5.262Citations (PDF)
152XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
Journal of Biological Chemistry, 2011, 286, 32638-32650
1.3160Citations (PDF)
153Neutralizing Mutations of Carboxylates That Bind Metal 2 in T5 Flap Endonuclease Result in an Enzyme That Still Requires Two Metal Ions
Journal of Biological Chemistry, 2011, 286, 30878-30887
1.313Citations (PDF)
154ATP Induces Conformational Changes in the Carboxyl-terminal Region of ClC-5
Journal of Biological Chemistry, 2011, 286, 6733-6741
1.319Citations (PDF)
155Ultrahigh Resolution and Full-length Pilin Structures with Insights for Filament Assembly, Pathogenic Functions, and Vaccine Potential
Journal of Biological Chemistry, 2011, 286, 44254-44265
1.370Citations (PDF)
156DNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent Complexes
Molecular and Cellular Biology, 2011, 31, 2299-2310
1.559Citations (PDF)
157Solution structure of RNase P RNA
Rna, 2011, 17, 1159-1171
2.547Citations (PDF)
158Alkyltransferase-like proteins: molecular switches between DNA repair pathways3.524Citations (PDF)
159Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering4.6153Citations (PDF)
160Structural dynamics in DNA damage signaling and repair4.647Citations (PDF)
161XLF Regulates Filament Architecture of the XRCC4·Ligase IV Complex
Structure, 2010, 18, 1431-1442
2.4108Citations (PDF)
162A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
DNA Repair, 2010, 9, 1307-1314
1.8199Citations (PDF)
163Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
DNA Repair, 2010, 9, 1299-1306
1.8205Citations (PDF)
164The structural biochemistry of the superoxide dismutases1.3494Citations (PDF)
165Software for the high-throughput collection of SAXS data using an enhancedBlu-Ice/DCScontrol system1.943Citations (PDF)
166Vibrio cholerae El Tor TcpA crystal structure and mechanism for pilus‐mediated microcolony formation
Molecular Microbiology, 2010, 77, 755-770
1.837Citations (PDF)
167γH2A binds Brc1 to maintain genome integrity during S‐phase
EMBO Journal, 2010, 29, 1136-1148
5.184Citations (PDF)
168Microbial metalloproteomes are largely uncharacterized
Nature, 2010, 466, 779-782
30.6361Citations (PDF)
169Repair of O4-Alkylthymine by O6-Alkylguanine-DNA Alkyltransferases
Journal of Biological Chemistry, 2010, 285, 8185-8195
1.328Citations (PDF)
170Identification of a Coiled Coil in Werner Syndrome Protein That Facilitates Multimerization and Promotes Exonuclease Processivity
Journal of Biological Chemistry, 2010, 285, 25699-25707
1.327Citations (PDF)
171Improving small-angle X-ray scattering data for structural analyses of the RNA world
Rna, 2010, 16, 638-646
2.587Citations (PDF)
172Structural Basis of O6-Alkylguanine Recognition by a Bacterial Alkyltransferase-like DNA Repair Protein
Journal of Biological Chemistry, 2010, 285, 13736-13741
1.326Citations (PDF)
173Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex
Journal of Biological Chemistry, 2010, 285, 1414-1423
1.3197Citations (PDF)
174Nitric-oxide Synthase Forms N-NO-pterin and S-NO-Cys
Journal of Biological Chemistry, 2010, 285, 31581-31589
1.340Citations (PDF)
175Recognition of the Ring-Opened State of Proliferating Cell Nuclear Antigen by Replication Factor C Promotes Eukaryotic Clamp-Loading11.742Citations (PDF)
176Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States
Biochemistry, 2010, 49, 6165-6176
1.5102Citations (PDF)
177Structural Dynamics and Single-Stranded DNA Binding Activity of the Three N-Terminal Domains of the Large Subunit of Replication Protein A from Small Angle X-ray Scattering
Biochemistry, 2010, 49, 2880-2889
1.546Citations (PDF)
178Crystal Structure of the First Eubacterial Mre11 Nuclease Reveals Novel Features that May Discriminate Substrates During DNA Repair
Journal of Molecular Biology, 2010, 397, 647-663
2.941Citations (PDF)
179Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes5.2121Citations (PDF)
180Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase
Nucleic Acids Research, 2009, 37, 6161-6173
10.751Citations (PDF)
181The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer
Structure, 2009, 17, 96-104
2.435Citations (PDF)
182Crystal and Solution Structures of a Prokaryotic M16B Peptidase: an Open and Shut Case
Structure, 2009, 17, 1465-1475
2.437Citations (PDF)
183Flipping of alkylated DNA damage bridges base and nucleotide excision repair
Nature, 2009, 459, 808-813
30.6128Citations (PDF)
184Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
Nature Methods, 2009, 6, 606-612
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185Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair5.897Citations (PDF)
186Molecular mimicry of SUMO promotes DNA repair5.856Citations (PDF)
187Contribution of Human Manganese Superoxide Dismutase Tyrosine 34 to Structure and Catalysis
Biochemistry, 2009, 48, 3417-3424
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188Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis
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189p38α MAP Kinase C-Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses2.954Citations (PDF)
190DNA apurinic-apyrimidinic site binding and excision by endonuclease IV5.8106Citations (PDF)
191Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase
Nature Chemical Biology, 2008, 4, 700-707
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192A SIM-ultaneous role for SUMO and ubiquitin5.8206Citations (PDF)
193Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1
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194XPD Helicase Structures and Activities: Insights into the Cancer and Aging Phenotypes from XPD Mutations
Cell, 2008, 133, 789-800
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195Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair
Cell, 2008, 135, 97-109
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196Repair of O6-G-Alkyl-O6-G Interstrand Cross-Links by Human O6-Alkylguanine-DNA Alkyltransferase
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197The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50
Biochemistry, 2008, 47, 11446-11456
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198Three Metal Ions Participate in the Reaction Catalyzed by T5 Flap Endonuclease
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199Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holocomplex in Genome Stability
Molecular Biology of the Cell, 2008, 19, 4099-4109
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200Coprinus cinereus rad50Mutants Reveal an Essential Structural Role for Rad50 in Axial Element and Synaptonemal Complex Formation, Homolog Pairing and Meiotic Recombination
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201Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV5.293Citations (PDF)
202The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase
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203Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair
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204Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin templateThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.1.5371Citations (PDF)
205Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography
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206Comparison of the Catalytic Parameters and Reaction Specificities of a Phage and an Archaeal Flap Endonuclease2.922Citations (PDF)
207Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS
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208The Case of the Missing Ring:  Radical Cleavage of a Carbon−Carbon Bond and Implications for GFP Chromophore Biosynthesis11.739Citations (PDF)
209Hexameric structures of the archaeal secretion ATPase GspE and implications for a universal secretion mechanism
EMBO Journal, 2007, 26, 878-890
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210SUMO‐targeted ubiquitin ligases in genome stability
EMBO Journal, 2007, 26, 4089-4101
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211The intricate structural chemistry of base excision repair machinery: Implications for DNA damage recognition, removal, and repair
DNA Repair, 2007, 6, 410-428
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212DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy
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213Understanding GFP Posttranslational Chemistry:  Structures of Designed Variants that Achieve Backbone Fragmentation, Hydrolysis, and Decarboxylation11.771Citations (PDF)
214Structural Evidence for an Enolate Intermediate in GFP Fluorophore Biosynthesis11.764Citations (PDF)
215Kinetic and structural characterization of human manganese superoxide dismutase containing 3-fluorotyrosines
Journal of Molecular Structure, 2006, 790, 168-173
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216A Novel Processive Mechanism for DNA Synthesis Revealed by Structure, Modeling and Mutagenesis of the Accessory Subunit of Human Mitochondrial DNA Polymerase
Journal of Molecular Biology, 2006, 358, 1229-1243
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217Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair
Molecular Cell, 2006, 22, 27-37
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218Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions
Molecular Cell, 2006, 23, 651-662
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219A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA
Molecular Cell, 2006, 24, 279-291
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220WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing5.8149Citations (PDF)
221Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage
EMBO Journal, 2006, 25, 3389-3397
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222Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction
Nucleic Acids Research, 2006, 34, 1540-1551
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223Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications
Nucleic Acids Research, 2006, 34, 6023-6033
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224Biochemical genetics of the mitochondrial replisome
FASEB Journal, 2006, 20,
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225The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca2+ transients in infected epithelial cells
Cellular Microbiology, 2005, 7, 1736-1748
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226DNA base damage recognition and removal: New twists and grooves1.2192Citations (PDF)
227The ATPase Activity of BfpD Is Greatly Enhanced by Zinc and Allosteric Interactions with Other Bfp Proteins
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228Crystallographic Structures of Discosoma Red Fluorescent Protein with Immature and Mature Chromophores:  Linking Peptide Bond Trans−Cis Isomerization and Acylimine Formation in Chromophore Maturation,
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229Biochemical Characterization and Crystal Structure of a Dim1 Family Associated Protein:  Dim2
Biochemistry, 2005, 44, 11997-12008
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230Defining the Role of Arginine 96 in Green Fluorescent Protein Fluorophore Biosynthesis†,‡
Biochemistry, 2005, 44, 16211-16220
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231Recognition of RNA Polymerase II and Transcription Bubbles by XPG, CSB, and TFIIH: Insights for Transcription-Coupled Repair and Cockayne Syndrome
Molecular Cell, 2005, 20, 187-198
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232Protein mimicry of DNA and pathway regulation
DNA Repair, 2005, 4, 1410-1420
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233Hydrogen Bonding in Human Manganese Superoxide Dismutase Containing 3-Fluorotyrosine
Biophysical Journal, 2005, 89, 4171-4179
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234Understanding GFP Chromophore Biosynthesis:  Controlling Backbone Cyclization and Modifying Post-translational Chemistry,
Biochemistry, 2005, 44, 1960-1970
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235Amino Acid Substitution at the Dimeric Interface of Human Manganese Superoxide Dismutase
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236Structural and functional analysis of Mre11-3
Nucleic Acids Research, 2004, 32, 1886-1893
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237Reaction Intermediates in the Catalytic Mechanism of Escherichia coli MutY DNA Glycosylase
Journal of Biological Chemistry, 2004, 279, 46930-46939
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238Structural Basis for Isozyme-specific Regulation of Electron Transfer in Nitric-oxide Synthase
Journal of Biological Chemistry, 2004, 279, 37918-37927
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239Interaction Interface of Human Flap Endonuclease-1 with Its DNA Substrates
Journal of Biological Chemistry, 2004, 279, 24394-24402
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240Type IV pilus structure and bacterial pathogenicity
Nature Reviews Microbiology, 2004, 2, 363-378
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241DNA binding and nucleotide flipping by the human DNA repair protein AGT5.8286Citations (PDF)
2422-Aminopyridines as Highly Selective Inducible Nitric Oxide Synthase Inhibitors. Differential Binding Modes Dependent on Nitrogen Substitution
Journal of Medicinal Chemistry, 2004, 47, 3320-3323
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243Role of Hydrogen Bonding in the Active Site of Human Manganese Superoxide Dismutase†,‡
Biochemistry, 2004, 43, 7038-7045
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244Nickel Superoxide Dismutase Structure and Mechanism
Biochemistry, 2004, 43, 8038-8047
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245Structure and function of the double-strand break repair machinery
DNA Repair, 2004, 3, 863-873
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246The Rad50 Signature Motif: Essential to ATP Binding and Biological Function
Journal of Molecular Biology, 2004, 335, 937-951
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247Differential Arrangements of Conserved Building Blocks among Homologs of the Rad50/Mre11 DNA Repair Protein Complex
Journal of Molecular Biology, 2004, 339, 937-949
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248Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
Cell, 2004, 116, 39-50
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249Differential Arrangements of Conserved Building Blocks among Homologs of the Rad50/Mre11 DNA Repair Protein Complex
Journal of Molecular Biology, 2004, 339, 937-949
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250Structural basis for endothelial nitric oxide synthase binding to calmodulin
EMBO Journal, 2003, 22, 766-775
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251Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures4.6200Citations (PDF)
252Manganese superoxide dismutase induction during measles virus infection
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253Characterization of the electrophile binding site and substrate binding mode of the 26-kDa glutathione S-transferase fromSchistosoma japonicum1.946Citations (PDF)
254Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2
EMBO Journal, 2003, 22, 4566-4576
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255Catalytic and Structural Effects of Amino Acid Substitution at Histidine 30 in Human Manganese Superoxide Dismutase:  Insertion of Valine Cγ into the Substrate Access Channel†
Biochemistry, 2003, 42, 2781-2789
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256Structural Basis for Recognition and Catalysis by the Bifunctional dCTP Deaminase and dUTPase from Methanococcus jannaschii
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257ALS Mutants of Human Superoxide Dismutase Form Fibrous Aggregates Via Framework Destabilization
Journal of Molecular Biology, 2003, 332, 601-615
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258Identification of a New Cryptochrome Class
Molecular Cell, 2003, 11, 59-67
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259Type IV Pilin Structure and Assembly
Molecular Cell, 2003, 11, 1139-1150
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260Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures5.2218Citations (PDF)
261Design of a monomeric human glutathione transferase GSTP1, a structurally stable but catalytically inactive protein2.237Citations (PDF)
262Kinetic Mechanism of Activation of the Cdk2/Cyclin A Complex
Journal of Biological Chemistry, 2002, 277, 23847-23853
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263Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans5.2133Citations (PDF)
264Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases
Journal of Molecular Biology, 2002, 315, 373-384
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265MDB: the Metalloprotein Database and Browser at The Scripps Research Institute
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266Structural Chemistry of a Green Fluorescent Protein Zn Biosensor11.7119Citations (PDF)
267Insights into Lou Gehrig's Disease from the Structure and Instability of the A4V Mutant of Human Cu,Zn Superoxide Dismutase
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268DNA double-strand break repair from head to tail4.6137Citations (PDF)
269The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
Nature, 2002, 418, 562-566
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270Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles:  Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 2002, 41, 13915-13925
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271Crystal structure and novel recognition motif of Rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis
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272Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication11Edited by K. Morikawa
Journal of Molecular Biology, 2001, 307, 541-556
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273Structure and mechanism of the RuvB holliday junction branch migration motor
Journal of Molecular Biology, 2001, 311, 297-310
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274The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases1.781Citations (PDF)
275Repair activities of 8-oxoguanine DNA glycosylase from Archaeoglobus fulgidus, a hyperthermophilic archaeon
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276Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase
Cell, 2001, 105, 473-485
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277Structures of Tetrahydrobiopterin Binding-Site Mutants of Inducible Nitric Oxide Synthase Oxygenase Dimer and Implicated Roles of Trp457†,‡
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278Kinetic Analysis of Product Inhibition in Human Manganese Superoxide Dismutase†
Biochemistry, 2001, 40, 12051-12058
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279Session 6 structural implications of BER enzymes: Dragons dancing—The structural biology of DNA base excision repair4.34Citations (PDF)
280The pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease
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281DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes4.332Citations (PDF)
282DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
Nature, 2000, 403, 451-456
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283Crystal structure and mutational analysis of the Saccharomyces cerevisiae cell cycle regulatory protein Cks1: implications for domain swapping, anion binding and protein interactions
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284DNA Mismatch Repair
Structure, 2000, 8, R237-R241
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285Uracil-DNA glycosylase-DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects5.2280Citations (PDF)
286Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine
Journal of Bacteriology, 2000, 182, 6036-6041
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287Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism 1 1Edited by R. Huber
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288Conserved structural motifs governing the stoichiometric repair of alkylated DNA by O6-alkylguanine-DNA alkyltransferase
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289Lessons learned from structural results on uracil-DNA glycosylase
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290Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3′ ends justify the means
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291Structural Biology of Rad50 ATPase
Cell, 2000, 101, 789-800
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292Structures of theNω-Hydroxy-l-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active and Inactive Pterins†,‡
Biochemistry, 2000, 39, 4608-4621
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293Multiple Replacements of Glutamine 143 in Human Manganese Superoxide Dismutase:  Effects on Structure, Stability, and Catalysis†
Biochemistry, 2000, 39, 7131-7137
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294Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding
EMBO Journal, 2000, 19, 1719-1730
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295Envisioning the Fourth Dimension of the Genetic Code: The Structural Biology of Macromolecular Recognition and Conformational Switching in DNA Repair1.66Citations (PDF)
296Tryptophan 409 Controls the Activity of Neuronal Nitric-oxide Synthase by Regulating Nitric Oxide Feedback Inhibition
Journal of Biological Chemistry, 1999, 274, 26907-26911
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297Mutational Analysis of the Tetrahydrobiopterin-binding Site in Inducible Nitric-oxide Synthase
Journal of Biological Chemistry, 1999, 274, 24100-24112
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298Interrupting the Hydrogen Bond Network at the Active Site of Human Manganese Superoxide Dismutase
Journal of Biological Chemistry, 1999, 274, 27711-27716
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299Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphology
Molecular Microbiology, 1999, 31, 743-752
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300Title is missing!
Nature Structural Biology, 1999, 6, 932-936
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301Envisioning the molecular choreography of DNA base excision repair4.6122Citations (PDF)
302Unraveling the effect of changes in conformation and compactness at the antibody VL-VH interface upon antigen binding1.929Citations (PDF)
303Structure of the DNA Repair Enzyme Endonuclease IV and Its DNA Complex
Cell, 1999, 98, 397-408
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304DNA REPAIR MECHANISMS FOR THE RECOGNITION AND REMOVAL OF DAMAGED DNA BASES17.4175Citations (PDF)
305Inducible nitric oxide synthase: role of the N-terminal β-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction
EMBO Journal, 1999, 18, 6260-6270
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306N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization
EMBO Journal, 1999, 18, 6271-6281
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307Role of Tryptophan 161 in Catalysis by Human Manganese Superoxide Dismutase
Biochemistry, 1999, 38, 11686-11692
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308Mutation of an Active Site Residue inEscherichia coliUracil-DNA Glycosylase:  Effect on DNA Binding, Uracil Inhibition and Catalysis†
Biochemistry, 1999, 38, 4834-4845
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309Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase 1 1Edited by D. C. Rees
Journal of Molecular Biology, 1999, 287, 331-346
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310Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products
Journal of Molecular Biology, 1999, 288, 427-439
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311Purification and Characterization of Thermotoga maritima Endonuclease IV, a Thermostable Apurinic/Apyrimidinic Endonuclease and 3′-Repair Diesterase
Journal of Bacteriology, 1999, 181, 2834-2839
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312Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
EMBO Journal, 1998, 17, 5214-5226
5.1461Citations (PDF)
313MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily
Nature Structural Biology, 1998, 5, 1058-1064
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314Flap endonuclease homologs in archaebacteria exist as independent proteins5.865Citations (PDF)
315Screening a peptidyl database for potential ligands to proteins with side-chain flexibility1.9110Citations (PDF)
316Substrate specificity of prostate-specific antigen (PSA)
Chemistry and Biology, 1998, 5, 475-488
4.787Citations (PDF)
317Consequences of the loss of O-linked glycosylation of meningococcal type IV pilin on piliation and pilus-mediated adhesion
Molecular Microbiology, 1998, 27, 705-715
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318Structure of the DNA Repair and Replication Endonuclease and Exonuclease FEN-1
Cell, 1998, 95, 135-146
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319Crystal Structure of Y34F Mutant Human Mitochondrial Manganese Superoxide Dismutase and the Functional Role of Tyrosine 34,
Biochemistry, 1998, 37, 4722-4730
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320Probing the Active Site of Human Manganese Superoxide Dismutase:  The Role of Glutamine 143,
Biochemistry, 1998, 37, 4731-4739
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321Newly Discovered Archaebacterial Flap Endonucleases Show a Structure-Specific Mechanism for DNA Substrate Binding and Catalysis Resembling Human Flap Endonuclease-1
Journal of Biological Chemistry, 1998, 273, 27154-27161
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322The Structure of Nitric Oxide Synthase Oxygenase Domain and Inhibitor Complexes
Science, 1997, 278, 425-431
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323Type-4 pilus-structure: outside to inside and top to bottom – aminireview
Gene, 1997, 192, 165-169
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324Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway
Structure, 1997, 5, 1543-1550
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325Consensus chemistry and R-turn conformation of the active core of the insect kinin neuropeptide family
Chemistry and Biology, 1997, 4, 105-117
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326The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites
EMBO Journal, 1997, 16, 6548-6558
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327Function of the Greek key connection analysed using circular permutants of superoxide dismutase
EMBO Journal, 1997, 16, 2171-2178
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328Exon 5 encoded domain is not required for the toxic function of mutant SOD1 but essential for the dismutase activity: identification and characterization of two new SOD1 mutations associated with familial amyotrophic lateral sclerosis
Neurogenetics, 1997, 1, 65-71
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329Computational, pulse-radiolytic, and structural investigations of lysine-136 and its role in the electrostatic triad of human C u,Z n superoxide dismutase
1997, 29, 103-112
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330A Mutation in the Human Cyclin-dependent Kinase Interacting Protein, CksHs2, Interferes With Cyclin-dependent Kinase Binding and Biological Function, but Preserves Protein Structure and Assembly
Journal of Molecular Biology, 1996, 261, 646-657
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331Human Mitochondrial Manganese Superoxide Dismutase Polymorphic Variant Ile58Thr Reduces Activity by Destabilizing the Tetrameric Interface†,‡
Biochemistry, 1996, 35, 4287-4297
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332Crystal Structure and Mutational Analysis of the Human CDK2 Kinase Complex with Cell Cycle–Regulatory Protein CksHs1
Cell, 1996, 84, 863-874
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333Unusual Trigonal-Planar Copper Configuration Revealed in the Atomic Structure of Yeast Copper−Zinc Superoxide Dismutase†,‡
Biochemistry, 1996, 35, 2316-2321
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334Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase.
EMBO Journal, 1996, 15, 3442-3447
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335Novel dimeric interface and electrostatic recognition in bacterial Cu,Zn superoxide dismutase5.290Citations (PDF)
336Human dUTP pyrophosphatase: uracil recognition by a β hairpin and active sites formed by three separate subunits
Structure, 1996, 4, 1077-1092
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337A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA
Nature, 1996, 384, 87-92
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338Glubodies: randomized libraries of glutathione transferase enzymes
Chemistry and Biology, 1996, 3, 359-367
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339Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
EMBO Journal, 1995, 14, 4108-4120
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340Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch.5.270Citations (PDF)
341Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium.5.2105Citations (PDF)
342Atomic and residue hydrophilicity in the context of folded protein structures1.979Citations (PDF)
343Structure and function of the multifunctional DNA-repair enzyme exonuclease III
Nature, 1995, 374, 381-386
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344Structure of the fibre-forming protein pilin at 2.6 Å resolution
Nature, 1995, 378, 32-38
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345Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1
Nature Structural Biology, 1995, 2, 561-568
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346The D90A mutation results in a polymorphism of Cu, Zn superoxide dismutase that is prevalent in northern Sweden and Finland
Human Molecular Genetics, 1995, 4, 1105-1108
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347A Role for Acidic Residues in Di-leucine Motif-based Targeting to the Endocytic Pathway
Journal of Biological Chemistry, 1995, 270, 19989-19997
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348Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis
Human Molecular Genetics, 1995, 4, 1113-1116
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349DNA repair proteins4.625Citations (PDF)
350Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
Cell, 1995, 80, 869-878
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351Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: Protein mimicry of DNA
Cell, 1995, 82, 701-708
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352The role of arginine 143 in the electrostatics and mechanism of Cu, Zn superoxide dismutase: Computational and experimental evaluation by mutational analysis1.9126Citations (PDF)
353Predicting molecular interactions and inducible complementarity: Fragment docking of fab-peptide complexes1.947Citations (PDF)
354Structure and Function of Escherichia coli Endonuclease III2.623Citations (PDF)
355Structure and Function of the DNA Repair Enzyme Exonuclease III from E. Coli2.616Citations (PDF)
356Cu, Zn and Mn superoxide dismutases; Crystal structures, mutants, and function2.30Citations (PDF)
357Molecular recognition in DNA-binding proteins and enzymes4.73Citations (PDF)
358Rational Design and Expression of a Heparin-Targeted Human Superoxide Dismutase1.525Citations (PDF)
359Purification, Crystallization and Space Group Determination of DNA Repair Enzyme Exonuclease III from E. coli
Journal of Molecular Biology, 1993, 229, 239-242
2.911Citations (PDF)
360Crystallographic Structures of Metalloenzymes for DNA Repair: The [4Fe-4S] Enzyme Endonuclease III Structure as a Prototype for DNA N-Glycosylase and AP Lyase2.20Citations (PDF)
361Altering the antigenicity of proteins.5.249Citations (PDF)
362Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase.5.2315Citations (PDF)
363The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles
Cell, 1992, 71, 107-118
23.4482Citations (PDF)
364The interdependence of protein surface topography and bound water molecules revealed by surface accessibility and fractal density measures2.9127Citations (PDF)
365Crystallization and crystallographic characterization of the iron-sulfur-containing DNA-repair enzyme endonuclease III from Escherichia coli
Journal of Molecular Biology, 1992, 227, 347-351
2.929Citations (PDF)
366Protein metal-binding sites4.775Citations (PDF)
367Thermostabilization of recombinant human and bovine CuZn superoxide dismutases by replacement of free cysteines1.578Citations (PDF)
368Probing the Structural Basis for Enzyme-Substrate Recognition In Cu, Zn Superoxide Dismutase2.115Citations (PDF)
369Synthesis and characterization of a recombinant myohemerythrin protein encoded by a synthetic gene
Gene, 1991, 99, 151-156
1.612Citations (PDF)
370Defining Antibody-Antigen Recognition: Towards Engineered Antibodies and Epitopes2.78Citations (PDF)
371Metal-binding sites in proteins4.7158Citations (PDF)
372Mechanism and Atomic Structure of Superoxide Dismutase2.116Citations (PDF)
373Active conformation of an insect neuropeptide family.5.280Citations (PDF)
374Antibody remodeling: a general solution to the design of a metal-coordination site in an antibody binding pocket.5.2107Citations (PDF)
375Enzyme motifs in antibodies
Nature, 1990, 348, 589-589
30.610Citations (PDF)
376Visualization of molecular flexibility and its effects on electrostatic recognition2.724Citations (PDF)
377Colour illustration2.70Citations (PDF)
378Elucidating the structural chemistry of glycosaminoglycan recognition by protein C inhibitor.5.265Citations (PDF)
379Crystallographic characterization of a Cu,Zn superoxide dismutase from Photobacterium leiognathi
Journal of Molecular Biology, 1990, 212, 449-451
2.912Citations (PDF)
380Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis
Cell, 1990, 63, 1061-1072
23.4539Citations (PDF)
381Evolution of CuZn superoxide dismutase and the Greek Key β-barrel structural motif1.9218Citations (PDF)
382Crystallographic structure of a photoreceptor protein at 2.4 A resolution5.273Citations (PDF)
383Genetically Engineered Polymers of Human CuZn Superoxide Dismutase
Journal of Biological Chemistry, 1989, 264, 5260-5268
1.386Citations (PDF)
384Selenocysteine's mechanism of incorporation and evolution revealed in cDNAs of three glutathione peroxidases2.289Citations (PDF)
385Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix.5.2151Citations (PDF)
386Three dimensional structure of bacterial pili
Antonie Van Leeuwenhoek, 1987, 53, 447-453
1.26Citations (PDF)
387Recognition and interactions controlling the assemblies of beta barrel domains
Biophysical Journal, 1986, 49, 191-206
1.543Citations (PDF)
388Kinetic studies of reduction of a 1:1 cytochrome c-flavodoxin complex by free flavin semiquinones and rubredoxin
Biochemistry, 1986, 25, 3318-3328
1.543Citations (PDF)
389Crystallographic characterization of recombinant human CuZn superoxide dismutase.
Journal of Biological Chemistry, 1986, 261, 16215-16218
1.352Citations (PDF)
390Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.5.2161Citations (PDF)
391Mobility and evolutionary variability factors in protein antigenicity (reply)
Nature, 1985, 317, 90-90
30.60Citations (PDF)
392The Atomic Mobility Component of Protein Antigenicity
Annual Review of Immunology, 1985, 3, 501-539
22.3216Citations (PDF)
393The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein
Nature, 1984, 312, 127-134
30.6508Citations (PDF)
394Structure and mechanism of copper, zinc superoxide dismutase
Nature, 1983, 306, 284-287
30.6982Citations (PDF)
395Electrostatic recognition between superoxide and copper, zinc superoxide dismutase
Nature, 1983, 306, 287-290
30.6567Citations (PDF)
396Determination and analysis of the 2 Å structure of copper, zinc superoxide dismutase
Journal of Molecular Biology, 1982, 160, 181-217
2.9974Citations (PDF)
397An illustrated museum of protein structures
Biophysical Journal, 1980, 32, 211-213
1.53Citations (PDF)
398Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1
ELife, 0, 6,
1.044Citations (PDF)
399RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability10.73Citations (PDF)
400Abstract 4033: Chemical trapping of inactive GRB2 dimer unveils a novel cancer vulnerability by coupling replication stress to anti-tumor immunity
Cancer Research, 0, 86, 4033-4033
2.60Citations (PDF)