| 1 | G Protein-Coupled Receptors: A Century of Research and Discovery | 12.5 | 115 | Citations (PDF) |
| 2 | Loss of biased signaling at a G protein-coupled receptor in overexpressed systems | 2.4 | 25 | Citations (PDF) |
| 3 | Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin | 7.6 | 48 | Citations (PDF) |
| 4 | GPCR-mediated β-arrestin activation deconvoluted with single-molecule precisionCell, 2022, 185, 1661-1675.e16 | 34.1 | 104 | Citations (PDF) |
| 5 | Signaling at the endosome: cryo‐EM structure of a GPCR–G protein–beta‐arrestin megacomplex | 5.5 | 41 | Citations (PDF) |
| 6 | <i>β</i>-Arrestin–Biased Allosteric Modulator Potentiates Carvedilol-Stimulated <i>β</i> Adrenergic Receptor Cardioprotection | 2.7 | 39 | Citations (PDF) |
| 7 | Unique Positive Cooperativity Between the <i>β</i>-Arrestin–Biased <i>β</i>-Blocker Carvedilol and a Small Molecule Positive Allosteric Modulator of the <i>β</i>2-Adrenergic Receptor | 2.7 | 28 | Citations (PDF) |
| 8 | The GPCR–β-arrestin complex allosterically activates C-Raf by binding its amino terminus | 2.2 | 23 | Citations (PDF) |
| 9 | Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes | 2.2 | 42 | Citations (PDF) |
| 10 | Synthetic nanobodies as angiotensin receptor blockers | 7.6 | 55 | Citations (PDF) |
| 11 | SnapShot: β-Arrestin FunctionsCell, 2020, 182, 1362-1362.e1 | 34.1 | 48 | Citations (PDF) |
| 12 | The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility | 7.6 | 37 | Citations (PDF) |
| 13 | Conformational Basis of G Protein-Coupled Receptor Signaling Versatility | 12.3 | 208 | Citations (PDF) |
| 14 | Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor | 36.4 | 230 | Citations (PDF) |
| 15 | Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc | 38.7 | 341 | Citations (PDF) |
| 16 | Detergent- and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein–coupled receptors | 2.2 | 49 | Citations (PDF) |
| 17 | Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex | 8.7 | 214 | Citations (PDF) |
| 18 | Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor ConformationsCell, 2019, 176, 468-478.e11 | 34.1 | 271 | Citations (PDF) |
| 19 | Distinctive Activation Mechanism for Angiotensin Receptor Revealed by a Synthetic NanobodyCell, 2019, 176, 479-490.e12 | 34.1 | 183 | Citations (PDF) |
| 20 | Biased signalling: from simple switches to allosteric microprocessors | 82.4 | 683 | Citations (PDF) |
| 21 | Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling | 7.6 | 74 | Citations (PDF) |
| 22 | A Serendipitous Scientist | 12.0 | 4 | Citations (PDF) |
| 23 | β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility | 3.9 | 48 | Citations (PDF) |
| 24 | Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 | 5.5 | 211 | Citations (PDF) |
| 25 | Small-Molecule Positive Allosteric Modulators of the<i>β</i><sub>2</sub>-Adrenoceptor Isolated from DNA-Encoded Libraries | 2.7 | 90 | Citations (PDF) |
| 26 | G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β
<sub>2</sub>
-adrenergic receptor | 5.5 | 65 | Citations (PDF) |
| 27 | Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library | 7.6 | 151 | Citations (PDF) |
| 28 | Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis | 7.6 | 366 | Citations (PDF) |
| 29 | β-Arrestin2 mediates progression of murine primary myelofibrosis | 5.4 | 7 | Citations (PDF) |
| 30 | Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor | 12.0 | 80 | Citations (PDF) |
| 31 | GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling | 34.1 | 556 | Citations (PDF) |
| 32 | The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome | 3.7 | 19 | Citations (PDF) |
| 33 | β-arrestin2 Is Necessary for Development of MPLW515L Mutant Primary MyelofibrosisBlood, 2015, 126, 486-486 | 4.2 | 0 | Citations (PDF) |
| 34 | Allosteric Modulation of β-Arrestin-biased Angiotensin II Type 1 Receptor Signaling by Membrane Stretch | 2.2 | 62 | Citations (PDF) |
| 35 | Divergent Transducer-specific Molecular Efficacies Generate Biased Agonism at a G Protein-coupled Receptor (GPCR) | 2.2 | 125 | Citations (PDF) |
| 36 | Regulation of<i>β</i><sub>2</sub>-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies | 2.7 | 136 | Citations (PDF) |
| 37 | Recent developments in biased agonism | 3.9 | 265 | Citations (PDF) |
| 38 | A Brief History of G‐Protein Coupled Receptors (Nobel Lecture) | 14.4 | 262 | Citations (PDF) |
| 39 | Eine kurze Geschichte der G‐Protein‐gekoppelten Rezeptoren (Nobel‐Aufsatz) | 1.4 | 9 | Citations (PDF) |
| 40 | Targeting β-arrestin2 Enhances Survival in a Murine Model of Chronic Myeloid LeukemiaBlood, 2013, 122, 857-857 | 4.2 | 0 | Citations (PDF) |
| 41 | Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors | 12.0 | 570 | Citations (PDF) |
| 42 | Quantifying Ligand Bias at Seven-Transmembrane Receptors | 2.7 | 378 | Citations (PDF) |
| 43 | Therapeutic potential of β-arrestin- and G protein-biased agonists | 7.7 | 507 | Citations (PDF) |
| 44 | β-arrestin-mediated receptor trafficking and signal transduction | 11.8 | 689 | Citations (PDF) |
| 45 | Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling | 6.7 | 407 | Citations (PDF) |
| 46 | Distinct Phosphorylation Sites on the β
<sub>2</sub>
-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin | 5.5 | 605 | Citations (PDF) |
| 47 | β-Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix | 12.7 | 88 | Citations (PDF) |
| 48 | Teaching old receptors new tricks: biasing seven-transmembrane receptors | 82.4 | 769 | Citations (PDF) |
| 49 | β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7 | 7.6 | 560 | Citations (PDF) |
| 50 | β-Arrestin-biased Agonism at the β2-Adrenergic Receptor | 2.2 | 239 | Citations (PDF) |
| 51 | β-Arrestin-mediated Signaling Regulates Protein Synthesis | 2.2 | 87 | Citations (PDF) |
| 52 | Pharmacological Characterization of Membrane-Expressed Human Trace Amine-Associated Receptor 1 (TAAR1) by a Bioluminescence Resonance Energy Transfer cAMP Biosensor | 2.7 | 149 | Citations (PDF) |
| 53 | The annual ASCI meeting: does nostalgia have a future? | 10.7 | 2 | Citations (PDF) |
| 54 | The Active Conformation of β-Arrestin1 | 2.2 | 130 | Citations (PDF) |
| 55 | A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling | 7.6 | 590 | Citations (PDF) |
| 56 | β-Arrestins and Cell Signaling | 17.2 | 1,339 | Citations (PDF) |
| 57 | Introduction to Special Section on β-Arrestins | 17.2 | 43 | Citations (PDF) |
| 58 | β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection | 10.7 | 431 | Citations (PDF) |
| 59 | New Roles for β-Arrestins in Cell Signaling: Not Just for Seven-Transmembrane Receptors | 13.4 | 290 | Citations (PDF) |
| 60 | Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation | 2.2 | 446 | Citations (PDF) |
| 61 | β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor | 2.2 | 697 | Citations (PDF) |
| 62 | Conformational Changes in β‐arrestin1: The Importance of β‐arrestin1’s N‐domain | 0.7 | 0 | Citations (PDF) |
| 63 | Summary of Wenner-Gren International Symposium Receptor-Receptor Interactions Among Heptaspanning Membrane Receptors: From Structure to Function | 2.5 | 6 | Citations (PDF) |
| 64 | Functional antagonism of different G protein-coupled receptor kinases for -arrestin-mediated angiotensin II receptor signaling | 7.6 | 335 | Citations (PDF) |
| 65 | Different G protein-coupled receptor kinases govern G protein and -arrestin-mediated signaling of V2 vasopressin receptor | 7.6 | 319 | Citations (PDF) |
| 66 | Transduction of Receptor Signals by ß-Arrestins | 36.4 | 1,650 | Citations (PDF) |
| 67 | Constitutive Protease-activated Receptor-2-mediated Migration of MDA MB-231 Breast Cancer Cells Requires Both β-Arrestin-1 and -2 | 2.2 | 163 | Citations (PDF) |
| 68 | Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor | 2.2 | 480 | Citations (PDF) |
| 69 | Stable Interaction between β-Arrestin 2 and Angiotensin Type 1A Receptor Is Required for β-Arrestin 2-mediated Activation of Extracellular Signal-regulated Kinases 1 and 2 | 2.2 | 81 | Citations (PDF) |
| 70 | Activation-dependent Conformational Changes in β-Arrestin 2 | 2.2 | 151 | Citations (PDF) |
| 71 | Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2 | 2.2 | 167 | Citations (PDF) |
| 72 | β-arrestins: traffic cops of cell signaling | 3.9 | 278 | Citations (PDF) |
| 73 | Historical review: A brief history and personal retrospective of seven-transmembrane receptors | 11.8 | 380 | Citations (PDF) |
| 74 | Independent -arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2 | 7.6 | 653 | Citations (PDF) |
| 75 | The Stability of the G Protein-coupled Receptor-β-Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation | 2.2 | 335 | Citations (PDF) |
| 76 | Desensitization, internalization, and signaling functions of -arrestins demonstrated by RNA interference | 7.6 | 224 | Citations (PDF) |
| 77 | β-Arrestin-2 regulates the development of allergic asthma | 10.7 | 101 | Citations (PDF) |
| 78 | β-Arrestin-2 regulates the development of allergic asthma | 10.7 | 173 | Citations (PDF) |
| 79 | Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi | 2.2 | 183 | Citations (PDF) |
| 80 | β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation | 2.2 | 354 | Citations (PDF) |
| 81 | Dancing with Different Partners: Protein Kinase A Phosphorylation of Seven Membrane-Spanning Receptors Regulates Their G Protein-Coupling Specificity | 2.7 | 167 | Citations (PDF) |
| 82 | Phosphorylation of β-Arrestin2 Regulates Its Function in Internalization of β2-Adrenergic Receptors | 2.4 | 88 | Citations (PDF) |
| 83 | Seven-transmembrane-spanning receptors and heart function | 38.7 | 905 | Citations (PDF) |
| 84 | Seven-transmembrane receptors | 78.9 | 2,537 | Citations (PDF) |
| 85 | Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors | 24.7 | 446 | Citations (PDF) |
| 86 | α-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro | 2.7 | 39 | Citations (PDF) |
| 87 | Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3 | 2.4 | 34 | Citations (PDF) |
| 88 | Myocardial G Protein‐Coupled Receptor Kinases: Implications for Heart Failure Therapy | 3.2 | 35 | Citations (PDF) |
| 89 | Palmitoylation Increases the Kinase Activity of the G Protein-Coupled Receptor Kinase, GRK6† | 2.4 | 50 | Citations (PDF) |
| 90 | G PROTEIN–COUPLED RECEPTOR KINASES | 17.7 | 1,261 | Citations (PDF) |
| 91 | Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor | 2.2 | 434 | Citations (PDF) |
| 92 | Costimulation of Adenylyl Cyclase and Phospholipase C by a Mutant 1B-Adrenergic Receptor Transgene Promotes Malignant Transformation of Thyroid Follicular Cells | 2.6 | 6 | Citations (PDF) |
| 93 | Identification of the G Protein-coupled Receptor Kinase Phosphorylation Sites in the Human β2-Adrenergic Receptor | 2.2 | 220 | Citations (PDF) |
| 94 | Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases | 2.2 | 500 | Citations (PDF) |
| 95 | Protein kinases that phosphorylate activated G protein‐coupled receptors | 0.7 | 514 | Citations (PDF) |
| 96 | Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation | 2.2 | 411 | Citations (PDF) |
| 97 | Identification, Quantification, and Localization of mRNA for Three Distinct Alpha<sub>1</sub>Adrenergic Receptor Subtypes in Human Prostate | 4.5 | 326 | Citations (PDF) |
| 98 | Cloning of the cDNA and Genes for the Hamster and Human β2-Adrenergic Receptors | 0.9 | 13 | Citations (PDF) |
| 99 | Regulation of the β<sub>2</sub>‐adrenergic receptor and its mRNA in the rat ventral prostate by testosterone | 2.7 | 49 | Citations (PDF) |
| 100 | Identification of the Subunit Structure of Rat Pineal Adrenergic Receptors by Photoaffinity Labeling | 3.9 | 12 | Citations (PDF) |
| 101 | Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model | 38.7 | 771 | Citations (PDF) |
| 102 | Effect of pertussis toxin on α2
-adrenoceptors: decreased formation of the high-affinity state for agonists | 2.7 | 19 | Citations (PDF) |
| 103 | Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase | 38.7 | 118 | Citations (PDF) |
| 104 | Title is missing! | 1.2 | 7 | Citations (PDF) |
| 105 | Beta-adrenergic receptors: Regulatory role of agonists | 2.1 | 7 | Citations (PDF) |
| 106 | ACTH‐RECEPTOR INTERACTION IN THE ADRENAL: A MODEL FOR THE INITIAL STEP IN THE ACTION OF HORMONES THAT STIMULATE ADENYL CYCLASE | 4.1 | 104 | Citations (PDF) |
