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618 papers • 77,298 citations • Sorted by year • Download PDF (PDF by citations)
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1Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy
Cancers, 2024, 16, 3272
4.01Citations (PDF)
2Metabolic Reprogramming in Colon Cancer Cells Persistently Infected with Newcastle Disease Virus
Cancers, 2023, 15, 811
4.02Citations (PDF)
375th anniversary of the British Journal of Cancer
British Journal of Cancer, 2023, 128, 401-401
5.70Citations (PDF)
4Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
British Journal of Cancer, 2023, 128, 958-966
5.760Citations (PDF)
5Predicting Breast Cancer Events in Ductal Carcinoma In Situ (DCIS) Using Generative Adversarial Network Augmented Deep Learning Model
Cancers, 2023, 15, 1922
4.02Citations (PDF)
6GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner
Cancer Research, 2023, 83, 3400-3413
0.63Citations (PDF)
7Targeting mitochondrial oxidative phosphorylation: lessons, advantages, and opportunities
British Journal of Cancer, 2023, 129, 897-899
5.712Citations (PDF)
8A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells
PLoS Genetics, 2023, 19, e1010979
3.32Citations (PDF)
9Investigations on Zinc Isotope Fractionation in Breast Cancer Tissue Using in vitro Cell Culture Uptake-Efflux Experiments2.77Citations (PDF)
10Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX4.812Citations (PDF)
11Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions
Cell Reports, 2022, 38, 110320
6.436Citations (PDF)
12Targeting hypoxia regulated sodium driven bicarbonate transporters reduces triple negative breast cancer metastasis
Neoplasia, 2022, 25, 41-52
7.213Citations (PDF)
13Role of Hypoxia in the Interferon Response5.08Citations (PDF)
14Abstract 5813: Glycogen synthesis as potential novel target in triple negative breast cancer: Glycogen synthase 1 expression in human breast cancers and the impact of downregulation on proliferation of preclinical models
Cancer Research, 2022, 82, 5813-5813
0.61Citations (PDF)
15Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation8.513Citations (PDF)
16Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast
Cancers, 2022, 14, 3916
4.03Citations (PDF)
17Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor
Cells, 2022, 11, 3595
4.81Citations (PDF)
18Dissecting the heritable risk of breast cancer: From statistical methods to susceptibility genes
Seminars in Cancer Biology, 2021, 72, 175-184
14.212Citations (PDF)
19Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer4.534Citations (PDF)
20Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast
British Journal of Cancer, 2021, 124, 1150-1159
5.711Citations (PDF)
21Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Clinical Cancer Research, 2021, 27, 2459-2469
6.453Citations (PDF)
22The Landscape of the Heritable Cancer Genome
Cancer Research, 2021, 81, 2588-2599
0.615Citations (PDF)
23Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling
Scientific Reports, 2021, 11,
3.714Citations (PDF)
24Unveiling Cancer Metabolism through Spontaneous and Coherent Raman Spectroscopy and Stable Isotope Probing
Cancers, 2021, 13, 1718
4.050Citations (PDF)
25Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation11.518Citations (PDF)
26Adipocyte-like signature in ovarian cancer minimal residual disease identifies metabolic vulnerabilities of tumor initiating cells
JCI Insight, 2021, ,
5.54Citations (PDF)
27Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer
British Journal of Cancer, 2021, 125, 534-546
5.712Citations (PDF)
28Machine learning to guide the use of adjuvant therapies for breast cancer
Nature Machine Intelligence, 2021, 3, 716-726
17.430Citations (PDF)
29Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugs
BMC Cancer, 2021, 21,
3.04Citations (PDF)
30The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer4.822Citations (PDF)
31ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression
Molecular Cancer Research, 2021, 19, 1957-1969
2.95Citations (PDF)
32Expression and functions of long non-coding RNA NEAT1 and isoforms in breast cancer
British Journal of Cancer, 2021, 126, 551-561
5.737Citations (PDF)
33ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype4.58Citations (PDF)
34Hypoxia Regulates Endogenous Double-Stranded RNA Production via Reduced Mitochondrial DNA Transcription2.716Citations (PDF)
35Characterising 18F-fluciclovine uptake in breast cancer through the use of dynamic PET/CT imaging
British Journal of Cancer, 2021, 126, 598-605
5.74Citations (PDF)
36Partial Breast Reconstruction with Lateral Chest Wall Perforator Flap to Facilitate Breast Conservation in Breast Cancer: First 100 Cases with Cancer Outcomes at 8 Years Follow-Up and the Lessons Learned
Cancer Management and Research, 2021, Volume 13, 9453-9466
1.98Citations (PDF)
37The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
Cell Reports, 2021, 37, 110103
6.418Citations (PDF)
38Comprehensive Imaging Characterization of Colorectal Liver Metastases2.79Citations (PDF)
39Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin
British Journal of Cancer, 2020, 122, 258-265
5.733Citations (PDF)
40Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells4.811Citations (PDF)
41The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer
PLoS ONE, 2020, 15, e0236187
2.521Citations (PDF)
42Hypoxia Induces Transcriptional and Translational Downregulation of the Type I IFN Pathway in Multiple Cancer Cell Types
Cancer Research, 2020, 80, 5245-5256
0.655Citations (PDF)
43Dysregulation at multiple points of the kynurenine pathway is a ubiquitous feature of renal cancer: implications for tumour immune evasion
British Journal of Cancer, 2020, 123, 137-147
5.720Citations (PDF)
44RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain
Angiogenesis, 2020, 23, 493-513
7.420Citations (PDF)
45COVID-19 and cancer research
British Journal of Cancer, 2020, 123, 689-690
5.717Citations (PDF)
46Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer
Scientific Reports, 2020, 10,
3.711Citations (PDF)
47Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration
British Journal of Cancer, 2020, 122, 1205-1210
5.728Citations (PDF)
48Clinical strategies to inhibit tumor vascularization
2020, , 147-176
1Citations (PDF)
49Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer
British Journal of Cancer, 2020, 124, 494-505
5.774Citations (PDF)
50Tumour subregion analysis of colorectal liver metastases using semi-automated clustering based on DCE-MRI: Comparison with histological subregions and impact on pharmacokinetic parameter analysis3.16Citations (PDF)
51HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer
Journal of Clinical Investigation, 2020, 130, 5074-5087
9.1224Citations (PDF)
52Glutamine deprivation alters the origin and function of cancer cell exosomes
EMBO Journal, 2020, 39,
7.477Citations (PDF)
53ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants3.410Citations (PDF)
54BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors14.1134Citations (PDF)
55Landscape of transcriptomic interactions between breast cancer and its microenvironment14.116Citations (PDF)
56Programmed death-1 receptor (PD-1) and PD-ligand-1 (PD-L1) expression in non-small cell lung cancer and the immune-suppressive effect of anaerobic glycolysis
Medical Oncology, 2019, 36,
2.540Citations (PDF)
57Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy
Molecular Cancer Therapeutics, 2019, 18, 2030-2042
1.732Citations (PDF)
58FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma1.419Citations (PDF)
59Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer7.795Citations (PDF)
60Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism
Molecular Cancer Research, 2019, 17, 1531-1544
2.920Citations (PDF)
61ATF4, Hypoxia and Treatment Resistance in Cancer0.02Citations (PDF)
62ADGRL4/ELTD1 Silencing in Endothelial Cells Induces ACLY and SLC25A1 and Alters the Cellular Metabolic Profile
Metabolites, 2019, 9, 287
3.517Citations (PDF)
633D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers1.717Citations (PDF)
64Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network1.84Citations (PDF)
65High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer
British Journal of Cancer, 2019, 122, 245-257
5.726Citations (PDF)
66Development of cancer metabolism as a therapeutic target: new pathways, patient studies, stratification and combination therapy5.727Citations (PDF)
67Non-angiogenic tumours and their influence on cancer biology
Nature Reviews Cancer, 2018, 18, 323-336
24.2117Citations (PDF)
68Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing1.415Citations (PDF)
69A first-in-human phase I study to determine the maximum tolerated dose of the oral Src/ABL inhibitor AZD0424
British Journal of Cancer, 2018, 118, 770-776
5.710Citations (PDF)
70SMER28 is a mTOR-independent small molecule enhancer of autophagy that protects mouse bone marrow and liver against radiotherapy
Investigational New Drugs, 2018, 36, 773-781
2.612Citations (PDF)
71miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense
Cancer Research, 2018, 78, 501-515
0.6104Citations (PDF)
72Advances in Hypoxia-Inducible Factor Biology
Cell Metabolism, 2018, 27, 281-298
26.3620Citations (PDF)
73Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors14.1100Citations (PDF)
74Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo
British Journal of Cancer, 2018, 119, 622-630
5.793Citations (PDF)
75Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer
Cell Metabolism, 2018, 28, 679-688.e4
26.397Citations (PDF)
76Consensus guidelines for the use and interpretation of angiogenesis assays
Angiogenesis, 2018, 21, 425-532
7.4445Citations (PDF)
77The glycerol backbone of phospholipids derives from noncarbohydrate precursors in starved lung cancer cells7.745Citations (PDF)
78Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases
Clinical Cancer Research, 2018, 24, 4694-4704
6.413Citations (PDF)
79Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer4.521Citations (PDF)
80A Novel Metal-Based Imaging Probe for Targeted Dual-Modality SPECT/MR Imaging of Angiogenesis3.636Citations (PDF)
81RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition
PLoS ONE, 2018, 13, e0191890
2.523Citations (PDF)
82miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration3.735Citations (PDF)
83A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1
Genes and Development, 2017, 31, 353-369
4.8168Citations (PDF)
84A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients
Clinical Cancer Research, 2017, 23, 4761-4768
6.495Citations (PDF)
85In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer
Molecular Cancer, 2017, 16,
29.823Citations (PDF)
86Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using 111In-bevacizumab
EJNMMI Research, 2017, 7,
2.72Citations (PDF)
87Pharmacodynamic and Pharmacokinetic Markers For Anti-angiogenic Cancer Therapy: Implications for Dosing and Selection of Patients2.16Citations (PDF)
88Single-cell heterogeneity in ductal carcinoma in situ of breast
Modern Pathology, 2017, 31, 406-417
5.040Citations (PDF)
89Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth
Oncotarget, 2017, 8, 40115-40131
1.734Citations (PDF)
90Galectin-3 acts as an angiogenic switch to induce tumor angiogenesis via Jagged-1/Notch activation
Oncotarget, 2017, 8, 49484-49501
1.765Citations (PDF)
91Hypoxia-related biological markers as predictors of epirubicin-based treatment responsiveness and resistance in locally advanced breast cancer
Oncotarget, 2017, 8, 78870-78881
1.79Citations (PDF)
92Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia
Genome Biology, 2016, 17,
8.471Citations (PDF)
93Biological and Prognostic Significance of the Morphological Types and Vascular Patterns in Colorectal Liver Metastases (CRLM)
Medicine (United States), 2016, 95, e2924
1.323Citations (PDF)
94Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth
Cancer Research, 2016, 76, 3744-3755
0.679Citations (PDF)
95Amino Acid Sensing by mTORC1: Intracellular Transporters Mark the Spot
Cell Metabolism, 2016, 23, 580-589
26.3206Citations (PDF)
96Labeling and preliminary in vivo assessment of niobium-labeled radioactive species: A proof-of-concept study
Nuclear Medicine and Biology, 2016, 43, 280-287
0.213Citations (PDF)
97Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment
EBioMedicine, 2016, 10, 109-116
10.028Citations (PDF)
98The Role of pH Regulation in Cancer Progression0.012Citations (PDF)
99Imaging oligometastatic cancer before local treatment
Lancet Oncology, The, 2016, 17, e406-e414
21.919Citations (PDF)
100MEF2 transcription factors are key regulators of sprouting angiogenesis
Genes and Development, 2016, 30, 2297-2309
4.863Citations (PDF)
101Normal tissue radioprotection by amifostine via Warburg-type effects3.729Citations (PDF)
102Why some tumours trigger neovascularisation and others don’t: the story thus far2.315Citations (PDF)
103Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia0.050Citations (PDF)
104Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy3.6180Citations (PDF)
105Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers
BMC Cancer, 2016, 16,
3.046Citations (PDF)
106Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments4.8190Citations (PDF)
107The tumour hypoxia induced non-coding transcriptome
Molecular Aspects of Medicine, 2016, 47-48, 35-53
9.399Citations (PDF)
108Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 2016, 12, 1-222
13.84,327Citations (PDF)
109Antiangiogenic therapy in oncology: current status and future directions
Lancet, The, 2016, 388, 518-529
35.3659Citations (PDF)
110Imaging biomarker roadmap for cancer studies25.3831Citations (PDF)
111The Role of Oxygen in Avascular Tumor Growth
PLoS ONE, 2016, 11, e0153692
2.548Citations (PDF)
112Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect
Oncotarget, 2016, 7, 76613-76627
1.722Citations (PDF)
113O-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer
Oncotarget, 2016, 7, 83570-83587
1.739Citations (PDF)
114Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth
Oncotarget, 2016, 7, 9353-9367
1.716Citations (PDF)
115Does Amifostine Reduce Metabolic Rate? Effect of the Drug on Gas Exchange and Acute Ventilatory Hypoxic Response in Humans
Pharmaceuticals, 2015, 8, 186-195
4.43Citations (PDF)
116Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines
PLoS ONE, 2015, 10, e0137675
2.5138Citations (PDF)
117Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition
Oncotarget, 2015, 6, 19413-19427
1.739Citations (PDF)
118Hypoxia metabolism in ageing
Aging, 2015, 7, 465-466
2.524Citations (PDF)
119Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer7.7114Citations (PDF)
120Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
Cancer Cell, 2015, 27, 57-71
33.4607Citations (PDF)
121Metabolic and hypoxic adaptation to anti‐angiogenic therapy: a target for induced essentiality
EMBO Molecular Medicine, 2015, 7, 368-379
7.2134Citations (PDF)
122A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors
Clinical Cancer Research, 2015, 21, 2695-2703
6.4130Citations (PDF)
123A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis
Angiogenesis, 2015, 18, 209-217
7.448Citations (PDF)
124International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013)2.045Citations (PDF)
125Carbonic Anhydrase Activity Monitored <i>In Vivo</i> by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors
Cancer Research, 2015, 75, 4109-4118
0.639Citations (PDF)
126Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer
Lung Cancer, 2015, 90, 98-105
2.174Citations (PDF)
127Neoadjuvant Window Studies of Metformin and Biomarker Development for Drugs Targeting Cancer Metabolism2.07Citations (PDF)
128Effect of Primary Letrozole Treatment on Tumor Expression of mTOR and HIF-1  and Relation to Clinical Response2.05Citations (PDF)
129The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions7.760Citations (PDF)
130The Role of Histone Demethylase KDM4B in Myc Signaling in Neuroblastoma5.162Citations (PDF)
131MicroRNA-Related DNA Repair/Cell-Cycle Genes Independently Associated With Relapse After Radiation Therapy for Early Breast Cancer0.719Citations (PDF)
132Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas
BMC Cancer, 2015, 15,
3.015Citations (PDF)
133Scarring, stem cells, scaffolds and skin repair2.862Citations (PDF)
134Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium5.388Citations (PDF)
135Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer
Clinical Cancer Research, 2015, 21, 955-961
6.4140Citations (PDF)
136Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways
Oncotarget, 2015, 6, 1920-1941
1.760Citations (PDF)
137Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer
Oncotarget, 2015, 6, 5678-5694
1.733Citations (PDF)
138Anoxia
2015, , 249-258
0Citations (PDF)
139Anoxia
2015, , 1-11
0Citations (PDF)
140Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer
Oncotarget, 2014, 5, 5934-5949
1.755Citations (PDF)
141ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer
Oncotarget, 2014, 5, 6633-6646
1.767Citations (PDF)
142JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues2.711Citations (PDF)
143Intracellular Carbonic Anhydrase Activity Sensitizes Cancer Cell pH Signaling to Dynamic Changes in CO2 Partial Pressure
Journal of Biological Chemistry, 2014, 289, 25418-25430
2.337Citations (PDF)
144Autophagy and lysosomal related protein expression patterns in human glioblastoma
Cancer Biology and Therapy, 2014, 15, 1468-1478
4.377Citations (PDF)
145Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation
Cell Reports, 2014, 9, 349-365
6.4505Citations (PDF)
146A review of ELTD1, a pro-angiogenic adhesion GPCR4.223Citations (PDF)
147Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells
Journal of Biological Chemistry, 2014, 289, 23168-23176
2.383Citations (PDF)
148The Notch ligand Jagged1 as a target for anti-tumor therapy2.7147Citations (PDF)
149Informed Consent, Biobank Research, and Locality1.313Citations (PDF)
150Functional comparison of Notch ligands in tumour angiogenesis0.50Citations (PDF)
151Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia
Molecular Cancer, 2014, 13, 28
29.8131Citations (PDF)
152The chemistry, physiology and pathology of pH in cancer4.1427Citations (PDF)
153Inhibitors of Tumor Angiogenesis
2014, , 275-317
1Citations (PDF)
154Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Nature Genetics, 2014, 46, 376-379
16.3256Citations (PDF)
155When Cancer Co-opts the Vasculature
New England Journal of Medicine, 2014, 370, 2146-2147
25.53Citations (PDF)
156Hypoxia and Metabolism in Cancer0.036Citations (PDF)
157Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER14.1194Citations (PDF)
158TRAP1 Regulates Proliferation, Mitochondrial Function, and Has Prognostic Significance in NSCLC
Molecular Cancer Research, 2014, 12, 660-669
2.959Citations (PDF)
159Glycogen metabolism in cancer
Biochemical Pharmacology, 2014, 92, 3-11
5.180Citations (PDF)
160The Hematopoietic Chemokine CXCL12 Promotes Integration of Human Endothelial Colony Forming Cell–Derived Cells into Immature Vessel Networks
Stem Cells and Development, 2014, 23, 2730-2743
2.119Citations (PDF)
161Seven In Absentia Homolog 2 (SIAH2) downregulation is associated with tamoxifen resistance in MCF-7 breast cancer cells
Journal of Surgical Research, 2014, 190, 203-209
1.810Citations (PDF)
162Extensive regulation of the non‐coding transcriptome by hypoxia: role of <scp>HIF</scp> in releasing paused <scp>RNA</scp> pol2
EMBO Reports, 2014, 15, 70-76
5.3137Citations (PDF)
163Proline-Hydroxylated Hypoxia-Inducible Factor 1α (HIF-1α) Upregulation in Human Tumours
PLoS ONE, 2014, 9, e88955
2.535Citations (PDF)
164Clinical Exploitation of Hypoxia0.00Citations (PDF)
165Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts3.664Citations (PDF)
166Erratum to “Microvessel networks pre-formed in artificial clinical grade dermal substitutes in vitro using cells from haematopoietic tissues” [Burns 38 (2012) 691–701]
Burns, 2013, 39, 194
2.10Citations (PDF)
167Overexpression of LC3A autophagy protein in follicular and diffuse large B-cell lymphomas0.711Citations (PDF)
168A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis
Cancer Cell, 2013, 24, 229-241
33.4242Citations (PDF)
169A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer
Clinical Cancer Research, 2013, 19, 4879-4888
6.4188Citations (PDF)
170A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours2.334Citations (PDF)
171Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia
Journal of Cellular Physiology, 2013, 228, 743-752
4.296Citations (PDF)
172An in vivo hypoxia metagene identifies the novel hypoxia inducible factor target gene SLCO1B3
European Journal of Cancer, 2013, 49, 1741-1751
3.312Citations (PDF)
173Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth4.8206Citations (PDF)
174Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial
Radiotherapy and Oncology, 2013, 108, 40-47
0.952Citations (PDF)
175New strategies for targeting the hypoxic tumour microenvironment in breast cancer
Cancer Treatment Reviews, 2013, 39, 171-179
10.1167Citations (PDF)
176Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma
European Journal of Cancer, 2013, 49, 156-165
3.337Citations (PDF)
177Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
Biochemical Journal, 2013, 449, 389-400
3.9126Citations (PDF)
178The G-Protein–Coupled Receptor CLR Is Upregulated in an Autocrine Loop with Adrenomedullin in Clear Cell Renal Cell Carcinoma and Associated with Poor Prognosis
Clinical Cancer Research, 2013, 19, 5740-5748
6.419Citations (PDF)
179P21-Activated Kinase 1 (PAK1) as a Therapeutic Target in BRAF Wild-Type Melanoma5.167Citations (PDF)
180Changing prognosis of renal cell carcinoma: a single-centre experience over 25 years
Journal of Clinical Urology, 2013, 6, 119-124
0.30Citations (PDF)
181Vessel co‐option in primary human tumors and metastases: an obstacle to effective anti‐angiogenic treatment?
Cancer Medicine, 2013, 2, 427-436
2.8226Citations (PDF)
182The use of bio‐metal concentrations correlated with clinical prognostic factors to assess human breast tissues
X-Ray Spectrometry, 2013, 42, 330-336
0.917Citations (PDF)
183Molecular Basis for Jagged-1/Serrate Ligand Recognition by the Notch Receptor
Journal of Biological Chemistry, 2013, 288, 7305-7312
2.326Citations (PDF)
184Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells<i>in vitro</i>5.376Citations (PDF)
185Microenvironmental Induced Essentiality of Autophagy
Clinical Cancer Research, 2013, 19, 2791-2793
6.42Citations (PDF)
186Regulation of Hypoxia Responses by MicroRNA Expression
2013, , 267-285
0Citations (PDF)
187The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity
Angiogenesis, 2013, 17, 77-91
7.416Citations (PDF)
188Targeting glycogen metabolism: a novel strategy to inhibit cancer cell growth?
Oncotarget, 2013, 4, 3-4
1.715Citations (PDF)
189Molecular Chemotherapy for Breast Cancer
Drugs and Aging, 2012, 14, 75-90
3.58Citations (PDF)
190Phase I Trial of Combretastatin A4 Phosphate (CA4P) in Combination with Bevacizumab in Patients with Advanced Cancer
Clinical Cancer Research, 2012, 18, 3428-3439
6.4152Citations (PDF)
191Metabolic compartments in tumor tissue: Implications for therapy
Cell Cycle, 2012, 11, 13-13
3.24Citations (PDF)
192Small-molecule inhibitors of the HIF pathway and synthetic lethal interactions3.916Citations (PDF)
193Response: Re: Delta-Like Ligand 4-Notch Blockade and Tumor Radiation Response5.10Citations (PDF)
194Acid-extrusion from Tissue: The Interplay Between Membrane Transporters and pH Buffers
Current Pharmaceutical Design, 2012, 18, 1331-1337
2.314Citations (PDF)
195How cancer metabolism is tuned for proliferation and vulnerable to disruption
Nature, 2012, 491, 364-373
40.1771Citations (PDF)
196Glucose Utilization via Glycogen Phosphorylase Sustains Proliferation and Prevents Premature Senescence in Cancer Cells
Cell Metabolism, 2012, 16, 751-764
26.3307Citations (PDF)
197ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer5.046Citations (PDF)
198Targeting the ATF4 pathway in cancer therapy3.9108Citations (PDF)
199Microvessel networks in pre-formed in artificial clinical grade dermal substitutes in vitro using cells from haematopoietic tissues
Burns, 2012, 38, 691-701
2.122Citations (PDF)
200Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones
Cancer Letters, 2012, 323, 77-87
8.570Citations (PDF)
201Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 2012, 8, 445-544
13.82,928Citations (PDF)
202Clinical Imaging of Tumor Angiogenesis
Future Oncology, 2012, 8, 1443-1459
2.414Citations (PDF)
203ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia
Molecular Biology Reports, 2012, 39, 10811-10822
2.626Citations (PDF)
204Importance of Intracellular pH in Determining the Uptake and Efficacy of the Weakly Basic Chemotherapeutic Drug, Doxorubicin
PLoS ONE, 2012, 7, e35949
2.590Citations (PDF)
205Gene Expression Analysis in Human Breast Cancer Associated Blood Vessels
PLoS ONE, 2012, 7, e44294
2.528Citations (PDF)
206Targeting Carbonic Anhydrases with Fluorescent BODIPY‐Labelled Sulfonamides1.911Citations (PDF)
207Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis<i>In Vivo</i>and Inhibition Enhances Anti-VEGF Therapy
Clinical Cancer Research, 2012, 18, 3100-3111
6.4204Citations (PDF)
208CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC
Carcinogenesis, 2012, 33, 1717-1725
2.947Citations (PDF)
209Expression of vascular Notch ligands Delta‐like 4 and Jagged‐1 in glioblastoma
Histopathology, 2012, 60, 740-747
3.940Citations (PDF)
210High DLL4 expression in tumour-associated vessels predicts for favorable radiotherapy outcome in locally advanced squamous cell head-neck cancer (HNSCC)
Angiogenesis, 2012, 16, 343-351
7.415Citations (PDF)
211Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression9.180Citations (PDF)
212Gene expression and hypoxia in breast cancer
Genome Medicine, 2011, 3, 55
9.972Citations (PDF)
213microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer
Cancer Research, 2011, 71, 5635-5645
0.6258Citations (PDF)
214Prognostic and Predictive Role of Lactate Dehydrogenase 5 Expression in Colorectal Cancer Patients Treated with PTK787/ZK 222584 (Vatalanib) Antiangiogenic Therapy
Clinical Cancer Research, 2011, 17, 4892-4900
6.4117Citations (PDF)
215Nuclear Localization of Factor Inhibitor Hypoxia-Inducible Factor in Prostate Cancer Is Associated With Poor Prognosis
Journal of Urology, 2011, 185, 1513-1518
4.49Citations (PDF)
216Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
Nature Medicine, 2011, 17, 1101-1108
25.6524Citations (PDF)
217miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors
Molecular Cell, 2011, 41, 210-220
14.2363Citations (PDF)
218The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen5.021Citations (PDF)
219Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers5.0149Citations (PDF)
220Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation
Radiotherapy and Oncology, 2011, 99, 424-431
0.9148Citations (PDF)
221Self assessment of health status and symptoms by cancer patients0.50Citations (PDF)
222Impact of Exploratory Biomarkers on the Treatment Effect of Bevacizumab in Metastatic Breast Cancer
Clinical Cancer Research, 2011, 17, 372-381
6.481Citations (PDF)
223New pathways and mechanisms regulating and responding to Delta-like ligand 4–Notch signalling in tumour angiogenesis4.215Citations (PDF)
224Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis3.71,046Citations (PDF)
225Antibody inhibiting enzymatic activity of tumour-associated carbonic anhydrase isoform IX4.436Citations (PDF)
226The angiogenic process as a therapeutic target in cancer
Biochemical Pharmacology, 2011, 81, 1183-1191
5.169Citations (PDF)
227The effect of different etiologies of hepatic impairment on the pharmacokinetics of gefitinib2.327Citations (PDF)
228Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas
BMC Cancer, 2011, 11,
3.023Citations (PDF)
229Notch3 signalling promotes tumour growth in colorectal cancer
Journal of Pathology, 2011, 224, 448-460
5.272Citations (PDF)
230Expression of hypoxia‐associated proteins in sporadic medullary thyroid cancer is associated with desmoplastic stroma reaction and lymph node metastasis and may indicate somatic mutations in the <i>VHL</i> gene
Journal of Pathology, 2011, 225, 63-72
5.236Citations (PDF)
231Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status
Journal of Pathology, 2011, 225, 4-11
5.2232Citations (PDF)
232Close and Stable Relationship between Proliferation and a Hypoxia Metagene in Aromatase Inhibitor–Treated ER-Positive Breast Cancer
Clinical Cancer Research, 2011, 17, 3005-3012
6.427Citations (PDF)
233Molecular Oncology and the Neoadjuvant Setting: the Perfect Blend for Treatment Personalization and Clinical Trial Design2.04Citations (PDF)
234Delta-Like Ligand 4–Notch Blockade and Tumor Radiation Response5.153Citations (PDF)
235Notch Regulation of Tumor Angiogenesis
Future Oncology, 2011, 7, 569-588
2.451Citations (PDF)
236Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells7.7168Citations (PDF)
237DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy <i>In Vivo</i>
Cancer Research, 2011, 71, 6073-6083
0.6197Citations (PDF)
238International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010)2.057Citations (PDF)
239Assessing Early Therapeutic Response to Bevacizumab in Primary Breast Cancer Using Magnetic Resonance Imaging and Gene Expression Profiles2.041Citations (PDF)
240Phosphorylated pVEGFR2/KDR receptor expression in uveal melanomas: relation with HIF2α and survival2.910Citations (PDF)
241Global MicroRNA Expression Profiling Identifies MiR-210 Associated with Tumor Proliferation, Invasion and Poor Clinical Outcome in Breast Cancer
PLoS ONE, 2011, 6, e20980
2.5184Citations (PDF)
242p21-activated kinase 1: PAK'ed with potential
Oncotarget, 2011, 2, 491-496
1.747Citations (PDF)
243Anoxia
2011, , 193-198
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244Diagnostic and Prognostic Cancer Biomarkers: From Traditional to Systems Approaches
2011, , 329-366
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245Automated uro‐oncology data collection: the Cancer Research Uro‐Oncology Database
BJU International, 2010, 105, 1663-1666
3.57Citations (PDF)
246New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
Blood, 2010, 116, 2385-2394
1.0332Citations (PDF)
247Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells
Haematologica, 2010, 95, 776-784
4.382Citations (PDF)
248Synergistic activity of letrozole and sorafenib on breast cancer cells2.531Citations (PDF)
249Anti-angiogenic effect of tamoxifen combined with epirubicin in breast cancer patients2.511Citations (PDF)
250Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase
Biochemical Pharmacology, 2010, 79, 1562-1572
5.118Citations (PDF)
251Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis4.1133Citations (PDF)
252hsa‐miR‐210 is a marker of tumor hypoxia and a prognostic factor in head and neck cancer
Cancer, 2010, 116, 2148-2158
4.4213Citations (PDF)
253Expression of key hypoxia sensing prolyl‐hydroxylases PHD1, ‐2 and ‐3 in pancreaticobiliary cancer
Histopathology, 2010, 56, 908-920
3.934Citations (PDF)
254Effects of HIF-1 and HIF2 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts
Journal of Oncology, 2010, 2010, 1-14
1.770Citations (PDF)
255MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU
PLoS ONE, 2010, 5, e10345
2.5267Citations (PDF)
256Spectral Clustering of Microarray Data Elucidates the Roles of Microenvironment Remodeling and Immune Responses in Survival of Head and Neck Squamous Cell Carcinoma
Journal of Clinical Oncology, 2010, 28, 2881-2888
17.165Citations (PDF)
257The Histone Demethylase JMJD2B Is Regulated by Estrogen Receptor α and Hypoxia, and Is a Key Mediator of Estrogen Induced Growth
Cancer Research, 2010, 70, 6456-6466
0.6157Citations (PDF)
258Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas1.779Citations (PDF)
259Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter
Journal of Clinical Investigation, 2010, 120, 2842-2857
9.183Citations (PDF)
260Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
Cancer Research, 2010, 70, 925-935
0.6165Citations (PDF)
261HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer
PLoS Biology, 2010, 8, e1000563
5.2110Citations (PDF)
262Targeting DLL4 in Tumors Shows Preclinical Activity But Potentially Significant Toxicity
Future Oncology, 2010, 6, 1099-1103
2.418Citations (PDF)
263Expression of Vascular Notch Ligand Delta-Like 4 and Inflammatory Markers in Breast Cancer
American Journal of Pathology, 2010, 176, 2019-2028
3.6102Citations (PDF)
264Roles of Tetrahydrobiopterin in Promoting Tumor Angiogenesis
American Journal of Pathology, 2010, 177, 2671-2680
3.629Citations (PDF)
265Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases
Cancer Letters, 2010, 296, 194-205
8.546Citations (PDF)
266Mechanisms of resistance to antiangiogenesis therapy
European Journal of Cancer, 2010, 46, 1323-1332
3.3140Citations (PDF)
2676-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
Cancer Research, 2010, 70, 6268-6276
0.693Citations (PDF)
268LC3A-Positive Light Microscopy Detected Patterns of Autophagy and Prognosis in Operable Breast Carcinomas
American Journal of Pathology, 2010, 176, 2477-2489
3.693Citations (PDF)
269Endothelial α3β1-Integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF
American Journal of Pathology, 2010, 177, 1534-1548
3.652Citations (PDF)
270Biomarkers to predict the clinical efficacy of bevacizumab in cancer
Lancet Oncology, The, 2010, 11, 1172-1183
21.9269Citations (PDF)
271Human endothelial stem/progenitor cells, angiogenic factors and vascular repair3.449Citations (PDF)
272The Role of Hypoxia Regulated microRNAs in Cancer0.030Citations (PDF)
273Angiogenesis - still a worthwhile target for breast cancer therapy?5.011Citations (PDF)
274A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
Genome Biology, 2010, 11,
8.4116Citations (PDF)
275The Tumor Microenvironment: New Insights into Regulation of Tumor pH by Carbonic Anhydrases
2010, , 23-41
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276Overexpression of <i>POLQ</i> Confers a Poor Prognosis in Early Breast Cancer Patients
Oncotarget, 2010, 1, 175-184
1.794Citations (PDF)
277Crosstalk of VEGF and Notch pathways in tumour angiogenesis: therapeutic implications6.5106Citations (PDF)
278Targeting the hypoxia-inducible factor (HIF) pathway in cancer4.9178Citations (PDF)
279Distinct MicroRNA Alterations Characterize High- and Low-Grade Bladder Cancer
Cancer Research, 2009, 69, 8472-8481
0.6267Citations (PDF)
280The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths
Journal of Biological Chemistry, 2009, 284, 20299-20310
2.3242Citations (PDF)
281Immunomodulation of FOXP3+ Regulatory T Cells by the Aromatase Inhibitor Letrozole in Breast Cancer Patients
Clinical Cancer Research, 2009, 15, 1046-1051
6.4132Citations (PDF)
282Phase I/II Trial of Bevacizumab and Radiotherapy for Locally Advanced Inoperable Colorectal Cancer: Vasculature-Independent Radiosensitizing Effect of Bevacizumab
Clinical Cancer Research, 2009, 15, 7069-7076
6.449Citations (PDF)
283Phosphorylated ERα, HIF-1α, and MAPK Signaling As Predictors of Primary Endocrine Treatment Response and Resistance in Patients With Breast Cancer
Journal of Clinical Oncology, 2009, 27, 227-234
17.1102Citations (PDF)
284Exon Array Analysis of Head and Neck Cancers Identifies a Hypoxia Related Splice Variant of LAMA3 Associated with a Poor Prognosis
PLoS Computational Biology, 2009, 5, e1000571
3.339Citations (PDF)
285A First-in-Man Phase I and Pharmacokinetic Study on CHR-2797 (Tosedostat), an Inhibitor of M1 Aminopeptidases, in Patients with Advanced Solid Tumors
Clinical Cancer Research, 2009, 15, 4978-4985
6.427Citations (PDF)
286Contribution of Granulocyte Colony-Stimulating Factor to the Acute Mobilization of Endothelial Precursor Cells by Vascular Disrupting Agents
Cancer Research, 2009, 69, 7524-7528
0.674Citations (PDF)
287The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
Cancer Research, 2009, 69, 4415-4423
0.6250Citations (PDF)
288Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues
BMC Genomics, 2009, 10,
3.274Citations (PDF)
289Nuclear and membrane expression of the angiogenesis regulator delta‐like ligand 4 (DLL4) in normal and malignant human tissues
Histopathology, 2009, 54, 598-606
3.916Citations (PDF)
290Corrigendum
Histopathology, 2009, 55, 463-464
3.90Citations (PDF)
291Role of Hypoxia‐Inducible Factors in Epigenetic Regulation via Histone Demethylases4.592Citations (PDF)
292Copper chelator ATN-224 inhibits endothelial function by multiple mechanisms
Microvascular Research, 2009, 77, 314-326
2.534Citations (PDF)
293Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies5.3161Citations (PDF)
294Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
Radiotherapy and Oncology, 2009, 92, 450-459
0.978Citations (PDF)
295Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
Blood, 2009, 114, 844-859
1.0262Citations (PDF)
296Clinical and immunological responses in metastatic melanoma patients vaccinated with a high-dose poly-epitope vaccine4.740Citations (PDF)
297Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies
Angiogenesis, 2008, 11, 41-51
7.482Citations (PDF)
298Expression of BNIP3 correlates with hypoxia‐inducible factor (HIF)‐1α, HIF‐2α and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines
Prostate, 2008, 68, 336-343
2.221Citations (PDF)
299Phosphorylated VEGFR2/KDR receptors are widely expressed in B‐cell non‐Hodgkin's lymphomas and correlate with hypoxia inducible factor activation
Hematological Oncology, 2008, 26, 219-224
2.228Citations (PDF)
300MicroRNA-10b and breast cancer metastasis
Nature, 2008, 455, E8-E9
40.1125Citations (PDF)
301Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2diffusion
BJU International, 2008, 101, 22-24
3.557Citations (PDF)
302Detection of elevated levels of tumour‐associated microRNAs in serum of patients with diffuse large B‐cell lymphoma
British Journal of Haematology, 2008, 141, 672-675
2.71,473Citations (PDF)
303The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer
Gynecologic Oncology, 2008, 110, 216-221
1.679Citations (PDF)
304Hypoxia response and microRNAs: no longer two separate worlds4.1170Citations (PDF)
305Evaluation of the current knowledge limitations in breast cancer research: a gap analysis5.082Citations (PDF)
306Phase I Study of Copper-Binding Agent ATN-224 in Patients with Advanced Solid Tumors
Clinical Cancer Research, 2008, 14, 7526-7534
6.485Citations (PDF)
307Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells
Microvascular Research, 2008, 75, 144-154
2.5174Citations (PDF)
308Activating transcription factor 42.6414Citations (PDF)
309Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway
Cancer Letters, 2008, 262, 87-93
8.521Citations (PDF)
310Targeting tumour hypoxia in breast cancer
European Journal of Cancer, 2008, 44, 2766-2773
3.366Citations (PDF)
311Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins
Leukemia and Lymphoma, 2008, 49, 2181-2186
1.616Citations (PDF)
312A Five-Gene Molecular Grade Index and <i>HOXB13:IL17BR</i> Are Complementary Prognostic Factors in Early Stage Breast Cancer
Clinical Cancer Research, 2008, 14, 2601-2608
6.4265Citations (PDF)
313BHLHB2 Controls<i>Bdnf</i>Promoter 4 Activity and Neuronal Excitability
Journal of Neuroscience, 2008, 28, 1118-1130
3.779Citations (PDF)
314Down-Regulation of Phosphatidylinositol 3′-Kinase/AKT/Molecular Target of Rapamycin Metabolic Pathway by Primary Letrozole-Based Therapy in Human Breast Cancer
Clinical Cancer Research, 2008, 14, 2673-2680
6.449Citations (PDF)
315Inhibitors of tumor angiogenesis
2008, , 351-381
0Citations (PDF)
316Tumor-associated Carbonic Anhydrase 9 Spatially Coordinates Intracellular pH in Three-dimensional Multicellular Growths
Journal of Biological Chemistry, 2008, 283, 20473-20483
2.3181Citations (PDF)
317Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors
Clinical Cancer Research, 2008, 14, 7917-7923
6.4334Citations (PDF)
318Regulation of CXCR4 by the Notch Ligand Delta-like 4 in Endothelial Cells
Cancer Research, 2008, 68, 1889-1895
0.653Citations (PDF)
319hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer
Clinical Cancer Research, 2008, 14, 1340-1348
6.4567Citations (PDF)
320Measuring Angiogenic Cytokines, Circulating Endothelial Cells, and Endothelial Progenitor Cells in Peripheral Blood and Cord Blood: VEGF and CXCL12 Correlate with the Number of Circulating Endothelial Progenitor Cells in Peripheral Blood2.628Citations (PDF)
321Macrophage Infiltration and Angiogenesis in Human Malignancy1.055Citations (PDF)
322HER2 Oncogenic Function Escapes EGFR Tyrosine Kinase Inhibitors via Activation of Alternative HER Receptors in Breast Cancer Cells
PLoS ONE, 2008, 3, e2881
2.565Citations (PDF)
323Hypoxic Regulation of Angiogenesis by HIF-1
2008, , 169-179
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324The Unfolded Protein Response and Integrated Stress Response to Anoxia: Fig. 1.
Clinical Cancer Research, 2007, 13, 2537-2540
6.445Citations (PDF)
325Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade
Journal of Clinical Oncology, 2007, 25, 1239-1246
17.1665Citations (PDF)
326Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers
Cancer Research, 2007, 67, 3441-3449
0.6306Citations (PDF)
327BNIP3 as a Progression Marker in Primary Human Breast Cancer; Opposing Functions in In situ Versus Invasive Cancer
Clinical Cancer Research, 2007, 13, 467-474
6.478Citations (PDF)
328Regulation of Hepatocyte Growth Factor Activator Inhibitor 2 by Hypoxia in Breast Cancer
Clinical Cancer Research, 2007, 13, 550-558
6.412Citations (PDF)
329177Lu-labeled-VG76e monoclonal antibody in tumor angiogenesis: A comparative study using DOTA and DTPA chelating systems
Radiochimica Acta, 2007, 95,
1.49Citations (PDF)
330Delta-like 4 Notch Ligand Regulates Tumor Angiogenesis, Improves Tumor Vascular Function, and Promotes Tumor Growth <i>In vivo</i>
Cancer Research, 2007, 67, 11244-11253
0.6269Citations (PDF)
331Strong Time Dependence of the 76-Gene Prognostic Signature for Node-Negative Breast Cancer Patients in the TRANSBIG Multicenter Independent Validation Series
Clinical Cancer Research, 2007, 13, 3207-3214
6.4776Citations (PDF)
332Genome-wide expression analysis using microarray identified complex signaling pathways modulated by hypoxia in nasopharyngeal carcinoma
Cancer Letters, 2007, 253, 74-88
8.544Citations (PDF)
333Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis?
Trends in Molecular Medicine, 2007, 13, 389-395
10.064Citations (PDF)
334Microvessel density as a prognostic factor in non-small-cell lung carcinoma: a meta-analysis of individual patient data
Lancet Oncology, The, 2007, 8, 488-499
21.961Citations (PDF)
335An Investigation Into the Prognostic Significance of Necrosis and Hypoxia in High Grade and Invasive Bladder Cancer
Journal of Urology, 2007, 178, 677-682
4.451Citations (PDF)
336Breast tumour angiogenesis5.0141Citations (PDF)
337Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer5.038Citations (PDF)
338Transcriptional Profiling of Human Cord Blood CD133+ and Cultured Bone Marrow Mesenchymal Stem Cells in Response to Hypoxia
Stem Cells, 2007, 25, 1003-1012
3.3142Citations (PDF)
339Macrophages and the hypoxic tumour microenvironment6.561Citations (PDF)
340The number of regulatory T cells in prostate cancer is associated with the androgen receptor and hypoxia-inducible factor (HIF)-2α but not HIF-1α
Prostate, 2007, 67, 623-629
2.227Citations (PDF)
341Expression of theforkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the Androgen receptor in prostate cancer but is not directly regulated by Androgens or hypoxia
Prostate, 2007, 67, 1091-1098
2.238Citations (PDF)
342Regulation of tumor pH and the role of carbonic anhydrase 97.2452Citations (PDF)
343The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer7.2103Citations (PDF)
344Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptorβ in primary invasive breast carcinomas2.545Citations (PDF)
345Carbonic anhydrase IX unifies spatial pH <sub>i</sub> regulation in large cell‐clusters
FASEB Journal, 2007, 21,
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346In vivo assessment of Delta like‐4 function in tumour development
FASEB Journal, 2007, 21,
0.70Citations (PDF)
347Gorham-Stout Syndrome: A Monocyte-Mediated Cytokine Propelled Disease5.161Citations (PDF)
348Introduction on Angiogenesis in Breast Cancer3.20Citations (PDF)
349The Role of Copper in Tumour Angiogenesis3.2155Citations (PDF)
350Mechanisms of Disease: angiogenesis in urologic malignancies
Nature Reviews Urology, 2006, 3, 157-169
1.744Citations (PDF)
351Comparison of Metabolic Pathways between Cancer Cells and Stromal Cells in Colorectal Carcinomas: a Metabolic Survival Role for Tumor-Associated Stroma
Cancer Research, 2006, 66, 632-637
0.6370Citations (PDF)
352Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis5.11,656Citations (PDF)
353C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1α gene define HIF-1α protein expression in non-small cell lung cancer
Lung Cancer, 2006, 53, 257-262
2.133Citations (PDF)
354Nuclear Factor-κB Signature of Inflammatory Breast Cancer by cDNA Microarray Validated by Quantitative Real-time Reverse Transcription-PCR, Immunohistochemistry, and Nuclear Factor-κB DNA-Binding
Clinical Cancer Research, 2006, 12, 3249-3256
6.496Citations (PDF)
355Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse
Journal of Clinical Oncology, 2006, 24, 5373-5380
17.1955Citations (PDF)
356Hypoxia-regulated differentiation: let's step it up a Notch
Trends in Molecular Medicine, 2006, 12, 141-143
10.054Citations (PDF)
357The Role of Cell-Free DNA Size Distribution in the Management of Prostate Cancer
Oncology Research, 2006, 16, 35-41
3.326Citations (PDF)
358Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
Blood, 2006, 107, 931-939
1.0300Citations (PDF)
359Proteomic identification of a role for the von Hippel Lindau tumour suppressor in changes in the expression of mitochondrial proteins and septin 2 in renal cell carcinoma
Proteomics, 2006, 6, 3880-3893
3.852Citations (PDF)
360Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer
Cancer Science, 2006, 97, 582-588
4.052Citations (PDF)
361Phosphorylated KDR expression in endometrial cancer cells relates to HIF1α/VEGF pathway and unfavourable prognosis
Modern Pathology, 2006, 19, 701-707
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362Phosphorylated KDR can be located in the nucleus of neoplastic cells
Cell Research, 2006, 16, 93-98
8.232Citations (PDF)
363Normoxic Stabilization of Hypoxia-Inducible Factor-1α by Modulation of the Labile Iron Pool in Differentiating U937 Macrophages: Effect of Natural Resistance–Associated Macrophage Protein 1
Cancer Research, 2006, 66, 2600-2607
0.681Citations (PDF)
364Notch Signaling in Breast Cancer and Tumor Angiogenesis: Cross-Talk and Therapeutic Potentials3.262Citations (PDF)
365Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis
Gynecologic Oncology, 2006, 103, 912-918
1.686Citations (PDF)
366Niacin induces PPARγ expression and transcriptional activation in macrophages via HM74 and HM74a-mediated induction of prostaglandin synthesis pathways
Biochemical Pharmacology, 2006, 71, 646-656
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367Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies
BMC Cancer, 2006, 6,
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368The relation between hypoxia‐inducible factor (HIF)‐1α and HIF‐2α expression with anemia and outcome in surgically treated head and neck cancer
Cancer, 2006, 107, 757-766
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369Impact of cyclins E, neutrophil elastase and proteinase 3 expression levels on clinical outcome in primary breast cancer patients
International Journal of Cancer, 2006, 119, 2539-2545
4.536Citations (PDF)
370Effects of Transferrin Receptor Blockade on Cancer Cell Proliferation and Hypoxia-Inducible Factor Function and Their Differential Regulation by Ascorbate
Cancer Research, 2006, 66, 2749-2756
0.663Citations (PDF)
371Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast Cancer5.11,011Citations (PDF)
372Hypoxia-Inducible Factor-1α Expression Predicts a Poor Response to Primary Chemoendocrine Therapy and Disease-Free Survival in Primary Human Breast Cancer
Clinical Cancer Research, 2006, 12, 4562-4568
6.4214Citations (PDF)
373Randomized Phase II Trial of Letrozole and Letrozole Plus Low-Dose Metronomic Oral Cyclophosphamide As Primary Systemic Treatment in Elderly Breast Cancer Patients
Journal of Clinical Oncology, 2006, 24, 3623-3628
17.1164Citations (PDF)
374Lactate Dehydrogenase 5 Expression in Operable Colorectal Cancer: Strong Association With Survival and Activated Vascular Endothelial Growth Factor Pathway—A Report of the Tumour Angiogenesis Research Group
Journal of Clinical Oncology, 2006, 24, 4301-4308
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375Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial
Journal of Clinical Oncology, 2006, 24, 727-735
17.1243Citations (PDF)
376Novel Thioredoxin Inhibitors Paradoxically Increase Hypoxia-Inducible Factor-α Expression but Decrease Functional Transcriptional Activity, DNA Binding, and Degradation
Clinical Cancer Research, 2006, 12, 5384-5394
6.443Citations (PDF)
377Prognostic Value of an Activation State Marker for Epidermal Growth Factor Receptor in Tissue Microarrays of Head and Neck Cancer
Cancer Research, 2006, 66, 2834-2843
0.648Citations (PDF)
378Identification of novel small-molecule inhibitors of hypoxia-inducible factor-1 transactivation and DNA binding
Molecular Cancer Therapeutics, 2006, 5, 2193-2202
1.757Citations (PDF)
379Up-Regulation of Endothelial Delta-like 4 Expression Correlates with Vessel Maturation in Bladder Cancer
Clinical Cancer Research, 2006, 12, 4836-4844
6.4120Citations (PDF)
380Hypoxia-induced genetic instability—a calculated mechanism underlying tumor progression3.6122Citations (PDF)
381Biological Therapies for Metastatic Breast Cancer: Antiangiogenesis
2006, , 671-704
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382Notch signaling from tumor cells: A new mechanism of angiogenesis
Cancer Cell, 2005, 8, 1-3
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383Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence4.584Citations (PDF)
384Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis2.4137Citations (PDF)
385Consensus statement: Expedition Inspiration 2004 Breast Cancer Symposium ?Breast Cancer ? the Development and Validation of New Therapeutics?2.55Citations (PDF)
386Angiogenin is up-regulated in the nucleus and cytoplasm in human primary breast carcinoma and is associated with markers of hypoxia but not survival
Journal of Pathology, 2005, 205, 585-591
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387Housekeeping proteins: A preliminary study illustrating some limitations as useful references in protein expression studies
Proteomics, 2005, 5, 566-571
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388Antiangiogenic Therapy
2005, ,
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389Relation of Erythropoietin and Erythropoietin Receptor Expression to Hypoxia and Anemia in Head and Neck Squamous Cell Carcinoma
Clinical Cancer Research, 2005, 11, 7614-7620
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390Antiangiogenic Activity of a Domain Deletion Mutant of Tissue Plasminogen Activator Containing Kringle 26.210Citations (PDF)
391Up-regulation of Delta-like 4 Ligand in Human Tumor Vasculature and the Role of Basal Expression in Endothelial Cell Function
Cancer Research, 2005, 65, 8690-8697
0.6305Citations (PDF)
392The Role of Hypoxia-Inducible Factor-1 in Three-dimensional Tumor Growth, Apoptosis, and Regulation by the Insulin-Signaling Pathway
Cancer Research, 2005, 65, 4147-4152
0.638Citations (PDF)
393Phase I Study of MetXia-P450 Gene Therapy and Oral Cyclophosphamide for Patients with Advanced Breast Cancer or Melanoma
Clinical Cancer Research, 2005, 11, 1512-1520
6.484Citations (PDF)
394The Androgen Receptor Is Significantly Associated with Vascular Endothelial Growth Factor and Hypoxia Sensing via Hypoxia-Inducible Factors HIF-1a, HIF-2a, and the Prolyl Hydroxylases in Human Prostate Cancer
Clinical Cancer Research, 2005, 11, 7658-7663
6.4132Citations (PDF)
395Prospective Study of Quantitation of Plasma DNA Levels in the Diagnosis of Malignant versus Benign Prostate Disease
Clinical Cancer Research, 2005, 11, 1394-1399
6.493Citations (PDF)
396Temozolomide Pharmacodynamics in Patients with Metastatic Melanoma: DNA Damage and Activity of Repair Enzymes O6-Alkylguanine Alkyltransferase and Poly(ADP-Ribose) Polymerase-1
Clinical Cancer Research, 2005, 11, 3402-3409
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397Inclusion of Vasculature-Related Variables in the Dukes Staging System of Colon Cancer
Clinical Cancer Research, 2005, 11, 8653-8660
6.432Citations (PDF)
398Immunodominance of Poxviral-Specific CTL in a Human Trial of Recombinant-Modified Vaccinia Ankara
Journal of Immunology, 2005, 175, 8431-8437
0.691Citations (PDF)
399Bone morphogenetic protein 2 (BMP-2) induces in vitro invasion and in vivo hormone independent growth of breast carcinoma cells3.626Citations (PDF)
400Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1
Radiotherapy and Oncology, 2005, 75, 89-98
0.9115Citations (PDF)
401HIF-2α expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia
Experimental Cell Research, 2005, 303, 447-456
3.167Citations (PDF)
402Pyruvate Dehydrogenase and Pyruvate Dehydrogenase Kinase Expression in Non Small Cell Lung Cancer and Tumor-Associated Stroma
Neoplasia, 2005, 7, 1-6
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403Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
Molecular and Cellular Biology, 2005, 25, 5675-5686
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404HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
Molecular Cell, 2005, 17, 793-803
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405Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1α expression
Modern Pathology, 2005, 19, 9-16
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406Metabolic profiling of hypoxia-inducible factor-1β-deficient and wild type Hepa-1 cells: effects of hypoxia measured by 1H magnetic resonance spectroscopy
Metabolomics, 2005, 1, 293-303
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407Increased Angiogenesis and Lymphangiogenesis in Inflammatory versus Noninflammatory Breast Cancer by Real-Time Reverse Transcriptase-PCR Gene Expression Quantification
Clinical Cancer Research, 2004, 10, 7965-7971
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408Activation of Peroxisome Proliferator-Activated Receptor δ Stimulates the Proliferation of Human Breast and Prostate Cancer Cell Lines
Cancer Research, 2004, 64, 3162-3170
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409Novel Mechanism of Action for Hydralazine
Circulation Research, 2004, 95, 162-169
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410BNIP3 Expression Is Linked with Hypoxia-Regulated Protein Expression and with Poor Prognosis in Non–Small Cell Lung Cancer
Clinical Cancer Research, 2004, 10, 5566-5571
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411A Phase II Study of Etanercept (Enbrel), a Tumor Necrosis Factor α Inhibitor in Patients with Metastatic Breast Cancer
Clinical Cancer Research, 2004, 10, 6528-6534
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412c-Myc Interacts with Hypoxia to Induce Angiogenesis In vivo by a Vascular Endothelial Growth Factor-Dependent Mechanism
Cancer Research, 2004, 64, 6563-6570
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413c-erbB-2 Related Aggressiveness in Breast Cancer Is Hypoxia Inducible Factor-1α Dependent
Clinical Cancer Research, 2004, 10, 7972-7977
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414Antiangiogenic Therapy for von Hippel-Lindau Disease13.760Citations (PDF)
415CITED4 Inhibits Hypoxia-Activated Transcription in Cancer Cells, and Its Cytoplasmic Location in Breast Cancer Is Associated with Elevated Expression of Tumor Cell Hypoxia-Inducible Factor 1α
Cancer Research, 2004, 64, 6075-6081
0.657Citations (PDF)
416Hypoxia-Inducible Factor 1α Expression as an Intrinsic Marker of Hypoxia
Clinical Cancer Research, 2004, 10, 8405-8412
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417Expression of Hypoxia-related Tissue Factors Correlates with Diminished Survival of Adjuvantly Treated Patients with Chromosome 1p Aberrant Oligodendroglial Neoplasms and Therapeutic Implications
Clinical Cancer Research, 2004, 10, 6567-6571
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418Noninvasive Measurements of Capecitabine Metabolism in Bladder Tumors Overexpressing Thymidine Phosphorylase by Fluorine-19 Magnetic Resonance Spectroscopy
Clinical Cancer Research, 2004, 10, 3863-3870
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419Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell–mediated immunotherapy
Journal of Clinical Investigation, 2004, 114, 1800-1811
9.1145Citations (PDF)
420Expression of the Forkhead Transcription Factor FOXP1 Is Associated with Estrogen Receptor α and Improved Survival in Primary Human Breast Carcinomas
Clinical Cancer Research, 2004, 10, 3521-3527
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421Histological quantitation of tumour angiogenesis
Apmis, 2004, 112, 413-430
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422Measuring tumor pharmacodynamic response using PET proliferation probes: the case for 2-[11C]-thymidine7.16Citations (PDF)
423Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
Journal of Biological Chemistry, 2004, 279, 38458-38465
2.3878Citations (PDF)
424Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer0.737Citations (PDF)
425Phosphorylated KDR is expressed in the neoplastic and stromal elements of human renal tumours and shuttles from cell membrane to nucleus
Journal of Pathology, 2004, 202, 313-320
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426The hypoxia-regulated transcription factor DEC1(Stra13, SHARP-2) and its expression in human tissues and tumours
Journal of Pathology, 2004, 203, 808-813
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427Non-linear survival analysis using neural networks
Statistics in Medicine, 2004, 23, 825-842
1.759Citations (PDF)
428Hypoxia-inducible factor-1? in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways4.5138Citations (PDF)
429Role of Carbonic Anhydrase IX in Human Tumor Cell Growth, Survival, and Invasion
Cancer Research, 2004, 64, 6160-6165
0.6251Citations (PDF)
430Hypoxia-inducible factors and hypoxic cell death in tumour physiology
Annals of Medicine, 2004, 36, 530-539
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431NOVELANGIOGENICSIGNALINGPATHWAYS ANDVASCULARTARGETS12.487Citations (PDF)
432Hypoxia Inducible Carbonic Anhydrase IX, Marker of Tumour: Hypoxia, Survival Pathway and Therapy Target
Cell Cycle, 2004, 3, 159-162
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433Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells
Blood, 2004, 103, 1876-1882
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434Gene expression signature for angiogenic and nonangiogenic non-small-cell lung cancer
Oncogene, 2004, 24, 1212-1219
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435Vascularization and expression of hypoxia-related tissue factors in intracranial ependymoma and their impact on patient survival
Acta Neuropathologica, 2004, 109, 211-216
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436High Serum YKL-40 Levels in Patients with Primary Breast Cancer is Related to Short Recurrence Free Survival2.5107Citations (PDF)
437Necrosis and Hypoxia in Invasive Breast Carcinoma2.595Citations (PDF)
438The Presence of a Fibrotic Focus in Invasive Breast Carcinoma Correlates with the Expression of Carbonic Anhydrase IX and is a Marker of Hypoxia and Poor Prognosis2.5104Citations (PDF)
439GLUT‐1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: Relationship to pimonidazole binding4.5189Citations (PDF)
440A population pharmacokinetic model for paclitaxel in the presence of a novel P-gp modulator, Zosuquidar Trihydrochloride (LY335979)2.822Citations (PDF)
441DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer
Journal of Pathology, 2003, 200, 222-228
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442Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer
Journal of Pathology, 2003, 200, 195-206
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443Expression of the cell death genes BNip3 and NIX in ductal carcinomain situ of the breast; correlation of BNip3 levels with necrosis and grade
Journal of Pathology, 2003, 201, 573-580
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444Title is missing!
Arthritis Research, 2003, 5, R193
4.6156Citations (PDF)
445Breast cancer classification and prognosis based on gene expression profiles from a population-based study7.71,636Citations (PDF)
446Comprehensive Proteomic Analysis of Breast Cancer Cell Membranes Reveals Unique Proteins with Potential Roles in Clinical Cancer
Journal of Biological Chemistry, 2003, 278, 6482-6489
2.3170Citations (PDF)
447Non-Nuclear Localized Human NOSII Enhances the Bioactivation and Toxicity of Tirapazamine (SR4233) in Vitro
Molecular Pharmacology, 2003, 63, 1248-1255
2.825Citations (PDF)
448NKT Cells Enhance CD4+ and CD8+ T Cell Responses to Soluble Antigen In Vivo through Direct Interaction with Dendritic Cells
Journal of Immunology, 2003, 171, 5140-5147
0.6417Citations (PDF)
449Carbonic Anhydrase IX Expression, a Novel Surrogate Marker of Tumor Hypoxia, Is Associated With a Poor Prognosis in Non–Small-Cell Lung Cancer
Journal of Clinical Oncology, 2003, 21, 473-482
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450Angiogenesis in Endocrine Tumors
Endocrine Reviews, 2003, 24, 600-632
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451Hypoxia-inducible factors 1?? and 2?? are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin
Melanoma Research, 2003, 13, 493-501
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452High-dose i.v. granisetron for the prevention of chemotherapy-induced emesis: cardiac safety and tolerability
Anti-Cancer Drugs, 2003, , 739-744
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453The cardiovascular safety of high-dose intravenous granisetron in cancer patients receiving highly emetogenic chemotherapy2.319Citations (PDF)
454Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1α2.326Citations (PDF)
455Vascular Patterns in Glioblastoma Influence Clinical Outcome and Associate with Variable Expression of Angiogenic Proteins: Evidence for Distinct Angiogenic Subtypes
Brain Pathology, 2003, 13, 133-143
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456Thymidine Phosphorylase Expression in Gallbladder Adenocarcinomas1.011Citations (PDF)
457Differential Gene Expression Patterns in HER2/neu-Positive and -Negative Breast Cancer Cell Lines and Tissues
American Journal of Pathology, 2002, 161, 1171-1185
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458ROLE OF THYMIDINE PHOSPHORYLASE IN AN IN VITRO MODEL OF HUMAN BLADDER CANCER INVASION
Journal of Urology, 2002, 167, 1482-1486
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459Drug inhibition of angiogenesis4.162Citations (PDF)
460HIF activation identifies early lesions in VHL kidneys
Cancer Cell, 2002, 1, 459-468
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461Angiogenesis in bladder cancer—prognostic marker and target for future therapy
Surgical Oncology, 2002, 11, 85-100
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462Preparation of the iodine-124 derivative of the Bolton-Hunter reagent ([124I]I-SHPP) and its use for labelling a VEGF antibody as a PET tracer0.911Citations (PDF)
463Association of hypoxia‐inducible factors 1α and 2α with activated angiogenic pathways and prognosis in patients with endometrial carcinoma
Cancer, 2002, 95, 1055-1063
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464Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer0.7284Citations (PDF)
465Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas
Journal of Pathology, 2002, 196, 416-422
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466Expression of carbonic anhydrase IX in breast is associated with malignant tissues and is related to overexpression of c-erbB2
Journal of Pathology, 2002, 197, 314-321
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467Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel‐Lindau gene and hypoxia
Journal of Pathology, 2002, 198, 502-510
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468A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis
Oncogene, 2002, 21, 282-290
6.672Citations (PDF)
469Hypoxia — a key regulatory factor in tumour growth
Nature Reviews Cancer, 2002, 2, 38-47
24.24,408Citations (PDF)
470Title is missing!3.2307Citations (PDF)
471Title is missing!2.912Citations (PDF)
472Diagnostic and Prognostic Significance of Tumor Angiogenesis
2002, , 151-176
1Citations (PDF)
473ROLE OF THYMIDINE PHOSPHORYLASE IN AN IN VITRO MODEL OF HUMAN BLADDER CANCER INVASION
Journal of Urology, 2002, , 1482-1486
4.41Citations (PDF)
474Hypoxia and oxidative stress in breast cancer Hypoxia and tumourigenesis5.094Citations (PDF)
475Measurement of Microvessel Density in Primary Tumors
2001, , 115-121
2Citations (PDF)
476Expression of the Hypoxia-Inducible and Tumor-Associated Carbonic Anhydrases in Ductal Carcinoma in Situ of the Breast
American Journal of Pathology, 2001, 158, 1011-1019
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477Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs
Lancet Oncology, The, 2001, 2, 278-289
21.9211Citations (PDF)
478Angiogenesis as a biomarker and target in cancer chemoprevention
Lancet Oncology, The, 2001, 2, 726-732
21.966Citations (PDF)
479Prognostic Significance of a Novel Hypoxia-Regulated Marker, Carbonic Anhydrase IX, in Invasive Breast Carcinoma
Journal of Clinical Oncology, 2001, 19, 3660-3668
17.1377Citations (PDF)
4808-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs2.311Citations (PDF)
481Nuclear expression of human apurinic/apyrimidinic endonuclease (HAP1/Ref-1) in head-and-neck cancer is associated with resistance to chemoradiotherapy and poor outcome0.7100Citations (PDF)
482VEGF-B expression in human primary breast cancers is associated with lymph node metastasis but not angiogenesis
Journal of Pathology, 2001, 193, 325-332
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483The angiogenic pathway ?vascular endothelial growth factor/flk-1(KDR)-receptor? in rheumatoid arthritis and osteoarthritis
Journal of Pathology, 2001, 194, 101-108
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484Plasminogen activator inhibitor-1 as a measure of vascular remodelling in breast cancer
Journal of Pathology, 2001, 195, 236-243
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485The angiogenic ?vascular endothelial growth factor/flk-1(KDR) receptor? pathway in patients with endometrial carcinoma
Cancer, 2001, 92, 2569-2577
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486Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
Differentiation, 2001, 69, 135-144
2.4246Citations (PDF)
487Detection of Mammaglobin mRNA in the Plasma of Breast Cancer Patients4.525Citations (PDF)
488The HIF Pathway: Implications for Patterns of Gene Expression in Cancer1.041Citations (PDF)
489Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
Journal of Pathology, 2000, 190, 430-436
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490‘Invading edge vs. inner’ (edvin) patterns of vascularization: an interplay between angiogenic and vascular survival factors defines the clinical behaviour of non-small cell lung cancer
Journal of Pathology, 2000, 192, 140-149
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491Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
Oncogene, 2000, 19, 6297-6305
6.6226Citations (PDF)
492The relative importance of NADPH: cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positions
Biochemical Pharmacology, 2000, 59, 993-996
5.137Citations (PDF)
493Title is missing!2.98Citations (PDF)
494Cid1, a Fission Yeast Protein Required for S-M Checkpoint Control when DNA Polymerase δ or ɛ Is Inactivated
Molecular and Cellular Biology, 2000, 20, 3234-3244
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495Evaluation of the alkaline comet assay and urinary 3-methyladenine excretion for monitoring DNA damage in melanoma patients treated with dacarbazine and tamoxifen2.316Citations (PDF)
496Angiogenesis in Pituitary Adenomas and the Normal Pituitary Gland4.4136Citations (PDF)
497A Shift in the Phenotype of Melan-A-Specific CTL Identifies Melanoma Patients with an Active Tumor-Specific Immune Response
Journal of Immunology, 2000, 165, 6644-6652
0.6121Citations (PDF)
498von Hippel‐Lindau Syndrome: Target for Anti‐Vascular Endothelial Growth Factor (VEGF) Receptor Therapy
Oncologist, 2000, 5, 32-36
3.649Citations (PDF)
499The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
American Journal of Pathology, 2000, 157, 411-421
3.61,116Citations (PDF)
500Platelet-derived endothelial cell growth factor expression and angiogenesis in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix1.218Citations (PDF)
501Hypoxia signalling in tumour angiogenesis1.03Citations (PDF)
502c-erbB-2 and Episialin Challenge Host Immune Response by HLA Class I Expression in Human Non–Small-Cell Lung Cancer
Journal of Immunotherapy, 2000, 23, 104-114
2.410Citations (PDF)
503Angiogenesis in Pituitary Adenomas and the Normal Pituitary Gland4.438Citations (PDF)
504von Hippel-Lindau Syndrome: Target for Anti-Vascular Endothelial Growth Factor (VEGF) Receptor Therapy
Oncologist, 2000, 5, 32-36
3.63Citations (PDF)
505Title is missing!2.923Citations (PDF)
506Title is missing!2.944Citations (PDF)
507MDM2 and MDMX bind and stabilize the p53-related protein p73
Current Biology, 1999, 9, 829-832
3.9108Citations (PDF)
508Reduction in angiogenesis after neoadjuvant chemoendocrine therapy in patients with operable breast carcinoma
Cancer, 1999, 85, 1996-2000
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509Combined role of tumor angiogenesis,bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma
1999, 86, 1421-1430
73Citations (PDF)
510Angiogenesisvs. response after combined chemoradiotherapy of squamous cell head and neck cancer
1999, 80, 810-817
32Citations (PDF)
511Nuclear localization of human AP endonuclease 1 (HAP1/Ref-1) associates with prognosis in early operable non-small cell lung cancer (NSCLC)
1999, 189, 351-357
40Citations (PDF)
512URINARY VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS CORRELATION WITH BLADDER CANCER RECURRENCE RATES
Journal of Urology, 1999, 161, 799-804
4.4113Citations (PDF)
513eIF4E expression in tumors: its possible role in progression of malignancies2.6297Citations (PDF)
514Angiogenesis in ductal breast carcinoma. Comparison of microvessel density between primary tumour and lymph node metastasis
Cancer Letters, 1999, 137, 145-150
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515Vascular endothelial growth factor platelet counts, and prognosis in renal cancer
Lancet, The, 1999, 353, 1494-1495
35.354Citations (PDF)
516Title is missing!
1999
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517Reduction in angiogenesis after neoadjuvant chemoendocrine therapy in patients with operable breast carcinoma
Cancer, 1999, 85, 1996-2000
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518Prognostic Significance of Tumor Vascularity
1999, , 317-339
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519URINARY VASCULAR ENDOTHELIAL GROWTH FACTOR AND ITS CORRELATION WITH BLADDER CANCER RECURRENCE RATES
Journal of Urology, 1999, , 799-804
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520Title is missing!
1998, 17, 187-194
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521Insulin-like growth factors in human breast cancer2.573Citations (PDF)
522Assessing the clinical impact of prognostic factors: When is "statistically significant" clinically useful?2.5160Citations (PDF)
523Neo-angiogenesis in locally advanced squamous cell head and neck cancer correlates with thymidine phosphorylase expression and p53 nuclear oncoprotein accumulation2.917Citations (PDF)
524Title is missing!
Angiogenesis, 1998, 2, 49-55
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525Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines
1998, 75, 706-712
51Citations (PDF)
526Validation of anti-vascular endothelial growth factor (anti-VEGF) antibodies for immunohistochemical localization of VEGF in tissue sections: expression of VEGF in the human endometrium
1998, 185, 402-408
61Citations (PDF)
527Expression of VEGF in routinely fixed material using a new monoclonal
1998, 186, 313-318
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528Are angiostatin and endostatin cures for cancer?
Lancet, The, 1998, 351, 1598-1599
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529Anti-angiogenic therapies in cancer clinical trials4.114Citations (PDF)
530Angiogenic Polypeptides in Breast Cancer: Expression of Mrna’s in Primary Human Tumours, MCF-7 Cell Transfection and Xenograft Models
1998, , 213-221
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531A Novel Cyclic Adenosine Monophosphate Analog Induces Hypercalcemia via Production of 1,25-Dihydroxyvitamin D in Patients with Solid Tumors4.420Citations (PDF)
532Resistance to Diverse Drugs and Ultraviolet Light Conferred by Overexpression of a Novel Human 26 S Proteasome Subunit
Journal of Biological Chemistry, 1997, 272, 30470-30475
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533Association of Tumor Angiogenesis With Bone Marrow Micrometastases in Breast Cancer Patients5.198Citations (PDF)
534Endothelial Cell-Specific Expression of Tumor Necrosis Factor-<i>α</i>from the KDR or E-Selectin Promoters Following Retroviral Delivery
Human Gene Therapy, 1997, 8, 2239-2247
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535cDNA Cloning of a Humandishevelled DVL-3Gene, Mapping to 3q27, and Expression in Human Breast and Colon Carcinomas2.120Citations (PDF)
536Expression of Wnt5a Is Downregulated by Extracellular Matrix and Mutated c-Ha-ras in the Human Mammary Epithelial Cell Line MCF-10A2.123Citations (PDF)
537Antiangiogenesis for cancer therapy
Lancet, The, 1997, 349, S13-S15
35.3111Citations (PDF)
538Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25
Gene, 1997, 189, 25-29
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539A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas
Oncogene, 1997, 14, 1249-1253
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540Targeting gene expression to hypoxic tumor cells
Nature Medicine, 1997, 3, 515-520
25.6324Citations (PDF)
541Title is missing!3.245Citations (PDF)
542Title is missing!
1997, 15, 15-28
59Citations (PDF)
543Title is missing!
Angiogenesis, 1997, 1, 36-37
7.412Citations (PDF)
544Platelet-derived endothelial cell growth factor (Thymidine Phosphorylase) expression in lung cancer
1997, 181, 196-199
50Citations (PDF)
545Potential role ofbcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer
1997, 74, 565-570
52Citations (PDF)
546Bcl-2 and p53 expression in node-negative breast carcinoma: A study with long-term follow-up
Human Pathology, 1996, 27, 1149-1155
2.488Citations (PDF)
547Mechanisms and therapeutic implications of angiogenesis2.361Citations (PDF)
548Breast cancer angiogenesis — new approaches to therapy via antiangiogenesis, hypoxic activated drugs, and vascular targeting2.547Citations (PDF)
549EARLY EXPRESSION OF bcl-2 PROTEIN IN THE ADENOMA-CARCINOMA SEQUENCE OF COLORECTAL NEOPLASIA
1996, 179, 10-14
50Citations (PDF)
550PROGNOSTIC VALUE OF ANGIOGENESIS IN OPERABLE NON-SMALL CELL LUNG CANCER
Journal of Pathology, 1996, 179, 80-88
5.2133Citations (PDF)
551TUMOUR ANGIOGENESIS
1996, 179, 232-237
116Citations (PDF)
552Bladder cancer angiogenesis, its role in recurrence, stage progression and as a therapeutic target7.216Citations (PDF)
553p53 Regulates the Minimal Promoter of the Human Topoisomerase II  Gene
Nucleic Acids Research, 1996, 24, 4464-4470
16.278Citations (PDF)
554Regulation of the Human Topoisomerase IIα Gene Promoter in Confluence-arrested Cells
Journal of Biological Chemistry, 1996, 271, 16741-16747
2.378Citations (PDF)
555Expression of messenger RNA for amphiregulin, heregulin, and cripto-1, three new members of the epidermal growth factor family, in human breast carcinomas2.575Citations (PDF)
556An open study to assess the safety, tolerance and pharmacokinetics of an intravenous infusion of granisetron given at 3 mg over 30 s in patients receiving chemotherapy for malignant disease2.324Citations (PDF)
557Platelet‐derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study
Journal of Pathology, 1995, 176, 183-190
5.2165Citations (PDF)
558Microvessel count predicts metastatic disease and survival in non‐small cell lung cancer
Journal of Pathology, 1995, 177, 57-63
5.2152Citations (PDF)
559Regulation of Wnt5a mRNA Expression in Human Mammary Epithelial Cells by Cell Shape, Confluence, and Hepatocyte Growth Factor
Journal of Biological Chemistry, 1995, 270, 12851-12856
2.352Citations (PDF)
560Re: Tumor Angiogenesis as a Prognostic Assay for Invasive Ductal Breast Carcinoma5.19Citations (PDF)
561Enhancement of Tumor Growth and Vascular Density by Transfection of Vascular Endothelial Cell Growth Factor Into MCF-7 Human Breast Carcinoma Cells5.1231Citations (PDF)
562Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis
Journal of Pathology, 1995, 177, 275-283
5.2366Citations (PDF)
563An Immunohistochemical and Prognostic Evaluation of Cathepsin D Expression in 105 Bladder Carcinomas
Journal of Urology, 1995, 154, 237-241
4.419Citations (PDF)
564Potential for protein kinase C inhibitors in cancer therapy0.017Citations (PDF)
565Expression of xenobiotic-metabolizing enzymes by primary and secondary hepatic tumors in man0.722Citations (PDF)
566The role of DT-diaphorase in determining the sensitivity of human tumor cells to tirapazamine (SR 4233)0.722Citations (PDF)
567What is the biological, prognostic, and therapeutic role of the EGF receptor in human breast cancer?2.519Citations (PDF)
568The epidermal growth factor receptor as a prognostic marker: Results of 370 patients and review of 3009 patients2.5131Citations (PDF)
569Tumor angiogenesis in node-negative breast carcinomas ? relationship with epidermal growth factor receptor, estrogen receptor, and survival2.5149Citations (PDF)
570Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer
Cancer, 1994, 74, 1021-1025
4.431Citations (PDF)
571Repair of cisplatin-DNA adducts by protein extracts from human ovarian carcinoma4.524Citations (PDF)
572bcl-2 in normal human breast and carcinoma, association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumours and in situ cancer
British Journal of Cancer, 1994, 69, 135-139
5.7274Citations (PDF)
573A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress
Nucleic Acids Research, 1994, 22, 4884-4889
16.2189Citations (PDF)
574Reversal of P-glycoprotein-mediated multidrug resistance by pure anti-oestrogens and novel tamoxifen derivatives
Biochemical Pharmacology, 1994, 48, 277-285
5.142Citations (PDF)
575Does improved control of tumour growth require an anti-cancer therapy targeting both neoplastic and intratumoral endothelial cells?
European Journal of Cancer, 1994, 30, 201-206
3.326Citations (PDF)
576Current approaches to targeting cancer using antiangiogenesis therapies
Cancer Treatment Reviews, 1994, 20, 393-412
10.146Citations (PDF)
577The role of topoisomerase IIα and β in drug resistance
Cancer Treatment Reviews, 1993, 19, 181-194
10.138Citations (PDF)
578Cathepsin D levels in primary breast cancers: Relationship with epidermal growth factor receptor, oestrogen receptor and axillary nodal status
European Journal of Cancer, 1993, 29, 426-428
3.314Citations (PDF)
579Angiogenesis in Breast Cancer.4.517Citations (PDF)
580bcl-2 Protein in Non-Small-Cell Lung Carcinoma25.5588Citations (PDF)
581Isolation of cDNA clones encoding the β isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24
Nucleic Acids Research, 1992, 20, 5587-5592
16.2218Citations (PDF)
582Bladder Cancer — Field versus Clonal Origin25.5108Citations (PDF)
583Mechanisms of Multidrug Resistance in Cancer Treatment
Acta Oncológica, 1992, 31, 205-213
1.9179Citations (PDF)
584p53, c-erbB-2 and the Epidermal Growth Factor Receptor in the Benign and Malignant Prostate
Journal of Urology, 1992, 147, 496-499
4.4155Citations (PDF)
585p53 Expression in Human Breast Cancer3.032Citations (PDF)
586Intermittent high-dose tamoxifen as a potential modifier of multidrug resistance
European Journal of Cancer, 1992, 28, 805-810
3.355Citations (PDF)
587Reduced topoisomerase II and elevated α class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C
Biochemical Pharmacology, 1992, 43, 685-693
5.139Citations (PDF)
588A study of adhesion molecules as markers of progression in malignant melanoma
Journal of Pathology, 1992, 167, 187-191
5.246Citations (PDF)
589Loss of HLA class-I alleles, heavy chains and β2-microglobulin in colorectal cancer4.556Citations (PDF)
590Novel growth regulatory factors and tumour angiogenesis1.0130Citations (PDF)
591Isolation and properties in culture of human adrenal capillary endothelial cells2.125Citations (PDF)
592Interleukin-4 is a potent mitogen for capillary endothelium2.184Citations (PDF)
593Modulation by verapamil of vincristine pharmacokinetics and sensitivity to metaphase arrest of the normal rat colon in organ culture
Biochemical Pharmacology, 1991, 41, 1217-1225
5.17Citations (PDF)
594Growth factors and receptors in cancer7.63Citations (PDF)
595Telling changes of base
Nature, 1991, 350, 377-378
40.149Citations (PDF)
596Assessment of renal toxicity by urinary enzymes in patients receiving chemotherapy with 8-methyl-8-acetylenic-putrescine2.30Citations (PDF)
597Mutant p53—the commonest genetic abnormality in human cancer?
Journal of Pathology, 1990, 162, 5-6
5.2113Citations (PDF)
598The epidermal growth factor receptor and the prognosis of bladder cancer
Cancer, 1990, 65, 1619-1625
4.4299Citations (PDF)
599Phase II study of doxorubicin plus ifosfamide/mesna in patients with advanced breast cancer
Cancer, 1990, 65, 2421-2425
4.420Citations (PDF)
600Enhancement of adriamycin® cytotoxicity in a multidrug resistant Chinese hamster ovary (CHO) subline, CHO-Adrr, by toremifene and its modulation by alpha1 acid glycoprotein1.021Citations (PDF)
601Epidermal growth factor receptor (EGFr) as a marker for poor prognosis in node-negative breast cancer patients: Neu and tamoxifen failure2.4127Citations (PDF)
602The quantitation by radioimmunoassay of 2′-deoxyuridine 5′-triphosphate in extracts of thymidylate synthase-inhibited cells
Analytical Biochemistry, 1989, 177, 347-352
2.512Citations (PDF)
603Cisplatin with high-dose infusions of hydroxyurea to inhibit DNA repair2.37Citations (PDF)
604Defective repair of DNA single- and double-strand breaks in the bleomycin- and X-ray-sensitive Chinese hamster ovary cell mutant, BLM-2
Mutation Research DNA Repair, 1989, 217, 93-100
3.714Citations (PDF)
605A phase II trial of ifosfamide/mesna with doxorubicin for malignant mesothelioma1.027Citations (PDF)
606Phase II study of low dose aminoglutethimide 250 mg/day plus hydrocortisone in advanced postmenopausal breast cancer1.013Citations (PDF)
607Epidermal growth factor receptors in breast cancer: Association with early relapse and death, poor response to hormones and interactions with neu1.3125Citations (PDF)
608Modulation of dipyridamole action by α1acid glycoprotein
Biochemical Pharmacology, 1989, 38, 3281-3288
5.116Citations (PDF)
609Chemotherapy induced emesis may exacerbate the nephrotoxicity of combined ifosfamide/mesna and cisplatin chemotherapy1.02Citations (PDF)
610Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells
Biochemical Pharmacology, 1988, 37, 2113-2120
5.115Citations (PDF)
611Adenosine-diphosphoribosyltransferase inhibitors can protect against or potentiate the cytotoxicity of S-phase acting drugs
Biochemical Pharmacology, 1988, 37, 2155-2160
5.18Citations (PDF)
612Bleomycin and X-ray-hypersensitive Chinese hamster ovary cell mutants: Genetic analysis and cross-resistance to neocarzinostatin2.14Citations (PDF)
613Phase II study of the antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717) in advanced breast cancer1.041Citations (PDF)
614The multidrug resistant phenotype in clinical practice; evaluation of cross resistance to ifosfamide and mesna after VP16–213, doxorubicin and vincristine (VPAV) for small cell lung cancer1.028Citations (PDF)
615Plasma prostaglandins in lung cancer1.08Citations (PDF)
616False-positive ketonuria during ifosfamide and mesna therapy1.06Citations (PDF)
617To branch or to expand?
ELife, 0, 5,
1.62Citations (PDF)
618Atf42.00Citations (PDF)