| 1 | Automated orthogonal tRNA generation | 9.6 | 12 | Citations (PDF) |
| 2 | Genetic Code-Locking Confers Stable Virus Resistance to a Recoded Organism | 1.8 | 1 | Citations (PDF) |
| 3 | Adding α,α-disubstituted and β-linked monomers to the genetic code of an organism | 31.8 | 70 | Citations (PDF) |
| 4 | Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli | 26.5 | 101 | Citations (PDF) |
| 5 | Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification | 10.8 | 4 | Citations (PDF) |
| 6 | Engineering Pyrrolysine Systems for Genetic Code Expansion and Reprogramming | 44.0 | 51 | Citations (PDF) |
| 7 | PERfect Day: reversible and dose-dependent control of circadian time-keeping in the mouse suprachiasmatic nucleus by translational switching of PERIOD2 protein expression | 1.7 | 6 | Citations (PDF) |
| 8 | Cell-of-origin-specific proteomics of extracellular vesicles. | 2.5 | 25 | Citations (PDF) |
| 9 | Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs | 16.8 | 43 | Citations (PDF) |
| 10 | Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly | 31.8 | 63 | Citations (PDF) |
| 11 | Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus | 5.3 | 56 | Citations (PDF) |
| 12 | Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons | 5.3 | 41 | Citations (PDF) |
| 13 | Mechanism-based traps enable protease and hydrolase substrate discovery | 31.8 | 64 | Citations (PDF) |
| 14 | RBBP6 activates the pre-mRNA 3′ end processing machinery in humans | 2.9 | 62 | Citations (PDF) |
| 15 | Discovery and Genetic Code Expansion of a Polyethylene Terephthalate (PET) Hydrolase from the Human Saliva Metagenome for the Degradation and Bio-Functionalization of PET | 11.8 | 64 | Citations (PDF) |
| 16 | Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching | 5.3 | 14 | Citations (PDF) |
| 17 | Refactored genetic codes enable bidirectional genetic isolation | 26.5 | 73 | Citations (PDF) |
| 18 | Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles | 16.8 | 62 | Citations (PDF) |
| 19 | Selective CRAF Inhibition Elicits Transactivation | 12.2 | 22 | Citations (PDF) |
| 20 | Sense codon reassignment enables viral resistance and encoded polymer synthesis | 26.5 | 190 | Citations (PDF) |
| 21 | A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design | 16.8 | 83 | Citations (PDF) |
| 22 | Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites | 8.8 | 85 | Citations (PDF) |
| 23 | Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids | 16.8 | 138 | Citations (PDF) |
| 24 | Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms | 31.8 | 120 | Citations (PDF) |
| 25 | Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs | 21.4 | 125 | Citations (PDF) |
| 26 | Reprogramming the genetic code | 29.7 | 246 | Citations (PDF) |
| 27 | Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion | 0.9 | 6 | Citations (PDF) |
| 28 | Efficient Phage Display with Multiple Distinct Non-Canonical Amino Acids Using Orthogonal Ribosome-Mediated Genetic Code Expansion | 11.8 | 67 | Citations (PDF) |
| 29 | Total synthesis of Escherichia coli with a recoded genome | 31.8 | 533 | Citations (PDF) |
| 30 | Frontispiz: Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion | 0.9 | 0 | Citations (PDF) |
| 31 | An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells | 1.8 | 77 | Citations (PDF) |
| 32 | Rapid and Efficient Generation of Stable Antibody–Drug Conjugates via an Encoded Cyclopropene and an Inverse‐Electron‐Demand Diels–Alder Reaction | 0.9 | 24 | Citations (PDF) |
| 33 | Detecting RNA base methylations in single cells by in situ hybridization | 11.0 | 35 | Citations (PDF) |
| 34 | Rapid and Efficient Generation of Stable Antibody–Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels–Alder Reaction | 11.8 | 99 | Citations (PDF) |
| 35 | Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix | 5.2 | 73 | Citations (PDF) |
| 36 | Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice | 5.3 | 41 | Citations (PDF) |
| 37 | Controlling orthogonal ribosome subunit interactions enables evolution of new function | 31.8 | 108 | Citations (PDF) |
| 38 | A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation | 11.0 | 34 | Citations (PDF) |
| 39 | Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs | 16.8 | 189 | Citations (PDF) |
| 40 | Genetically Encoded Protein Phosphorylation in Mammalian Cells | 4.8 | 72 | Citations (PDF) |
| 41 | Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release | 3.9 | 14 | Citations (PDF) |
| 42 | Pyrophosphorylation via selective phosphoprotein derivatization† | 5.7 | 19 | Citations (PDF) |
| 43 | Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid | 31.8 | 130 | Citations (PDF) |
| 44 | Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis | 12.2 | 65 | Citations (PDF) |
| 45 | Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing | 14.1 | 161 | Citations (PDF) |
| 46 | Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst†‡ | 5.7 | 21 | Citations (PDF) |
| 47 | Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET | 2.7 | 8 | Citations (PDF) |
| 48 | Expanding and reprogramming the genetic code | 31.8 | 764 | Citations (PDF) |
| 49 | Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling† | 1.8 | 46 | Citations (PDF) |
| 50 | Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells | 6.0 | 62 | Citations (PDF) |
| 51 | Labeling and identifying cell-specific proteomes in the mouse brain | 21.4 | 84 | Citations (PDF) |
| 52 | Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity | 4.5 | 68 | Citations (PDF) |
| 53 | Genetic code expansion in the mouse brain | 9.6 | 134 | Citations (PDF) |
| 54 | Tagging and Enriching Proteins Enables Cell-Specific Proteomics | 4.8 | 57 | Citations (PDF) |
| 55 | Defining synonymous codon compression schemes by genome recoding | 31.8 | 177 | Citations (PDF) |
| 56 | Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes | 12.2 | 47 | Citations (PDF) |
| 57 | Genetic code expansion in stable cell lines enables encoded chromatin modification | 14.1 | 165 | Citations (PDF) |
| 58 | Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation* | 1.3 | 52 | Citations (PDF) |
| 59 | Ribosome Subunit Stapling for Orthogonal Translation in E. coli. | 0.9 | 21 | Citations (PDF) |
| 60 | Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog | 9.6 | 243 | Citations (PDF) |
| 61 | Selective, rapid and optically switchable regulation of protein function in live mammalian cells | 16.8 | 161 | Citations (PDF) |
| 62 | Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers | 2.3 | 54 | Citations (PDF) |
| 63 | Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne | 3.0 | 46 | Citations (PDF) |
| 64 | Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization | 11.0 | 61 | Citations (PDF) |
| 65 | Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins | 12.2 | 183 | Citations (PDF) |
| 66 | Ribosome Subunit Stapling for Orthogonal Translation in E. coli | 11.8 | 73 | Citations (PDF) |
| 67 | Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET | 16.8 | 270 | Citations (PDF) |
| 68 | Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins | 12.2 | 148 | Citations (PDF) |
| 69 | Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins | 44.0 | 1,026 | Citations (PDF) |
| 70 | Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells | 12.2 | 170 | Citations (PDF) |
| 71 | Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation | 12.2 | 168 | Citations (PDF) |
| 72 | Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1 | 12.2 | 278 | Citations (PDF) |
| 73 | Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation† | 5.7 | 270 | Citations (PDF) |
| 74 | Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal | 4.6 | 32 | Citations (PDF) |
| 75 | Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal | 21.4 | 191 | Citations (PDF) |
| 76 | Expanding and Reprogramming the Genetic Code of Cells and Animals | 14.1 | 499 | Citations (PDF) |
| 77 | Strain-promoted sydnone bicyclo-[6.1.0]-nonyne cycloaddition† | 5.7 | 135 | Citations (PDF) |
| 78 | Genetically Encoded Light-Activated Transcription for Spatiotemporal Control of Gene Expression and Gene Silencing in Mammalian Cells | 12.2 | 98 | Citations (PDF) |
| 79 | Efficient and Rapid C. elegans Transgenesis by Bombardment and Hygromycin B Selection | 1.5 | 81 | Citations (PDF) |
| 80 | DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition | 31.8 | 258 | Citations (PDF) |
| 81 | Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction | 16.8 | 484 | Citations (PDF) |
| 82 | Expanding the genetic code of Drosophila melanogaster | 9.6 | 196 | Citations (PDF) |
| 83 | Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions | 12.2 | 537 | Citations (PDF) |
| 84 | Die Umprogrammierung des genetischen Codes: vom Triplett- zum Quadruplettcode | 0.9 | 5 | Citations (PDF) |
| 85 | Designer proteins: applications of genetic code expansion in cell biology | 69.9 | 355 | Citations (PDF) |
| 86 | Photocontrol of Tyrosine Phosphorylation in Mammalian Cells via Genetic Encoding of Photocaged Tyrosine | 12.2 | 169 | Citations (PDF) |
| 87 | Reprogramming the Genetic Code: From Triplet to Quadruplet Codes | 11.8 | 86 | Citations (PDF) |
| 88 | Light-Activated Kinases Enable Temporal Dissection of Signaling Networks in Living Cells | 12.2 | 159 | Citations (PDF) |
| 89 | Genetically encoding an aliphatic diazirine for protein photocrosslinking† | 5.7 | 97 | Citations (PDF) |
| 90 | Traceless and Site-Specific Ubiquitination of Recombinant Proteins | 12.2 | 183 | Citations (PDF) |
| 91 | Genetically Encoded 1,2-Aminothiols Facilitate Rapid and Site-Specific Protein Labeling via a Bio-orthogonal Cyanobenzothiazole Condensation | 12.2 | 169 | Citations (PDF) |
| 92 | A dual role of H4K16 acetylation in the establishment of yeast silent chromatin | 5.2 | 96 | Citations (PDF) |
| 93 | Expanding the Genetic Code of an Animal | 12.2 | 243 | Citations (PDF) |
| 94 | Reprogramming the genetic code | 5.2 | 28 | Citations (PDF) |
| 95 | Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration | 5.3 | 94 | Citations (PDF) |
| 96 | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains | 5.3 | 153 | Citations (PDF) |
| 97 | Genetically Directing ɛ-N, N-Dimethyl--Lysine in Recombinant Histones | 2.0 | 87 | Citations (PDF) |
| 98 | Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome | 31.8 | 620 | Citations (PDF) |
| 99 | Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization | 9.6 | 117 | Citations (PDF) |
| 100 | Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase | 9.6 | 296 | Citations (PDF) |
| 101 | Evolved orthogonal ribosome purification for in vitro characterization. | 11.2 | 27 | Citations (PDF) |
| 102 | De Novo Generation of Mutually Orthogonal Aminoacyl-tRNA Synthetase/tRNA Pairs | 12.2 | 91 | Citations (PDF) |
| 103 | Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair | 12.2 | 218 | Citations (PDF) |
| 104 | Genetically Encoded Photocontrol of Protein Localization in Mammalian Cells | 12.2 | 261 | Citations (PDF) |
| 105 | Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNACUA Pair and Click Chemistry | 12.2 | 315 | Citations (PDF) |
| 106 | A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation | 8.8 | 507 | Citations (PDF) |
| 107 | Genetically Encoding Nϵ-Methyl-l-lysine in Recombinant Histones | 12.2 | 162 | Citations (PDF) |
| 108 | Synthesis of orthogonal transcription-translation networks | 5.3 | 130 | Citations (PDF) |
| 109 | Genetically encoding Nε-acetyllysine in recombinant proteins | 9.6 | 595 | Citations (PDF) |
| 110 | Genetically Encoding Protein Oxidative Damage | 12.2 | 113 | Citations (PDF) |
| 111 | Engineering Escherichia coli heat-resistance by synthetic gene amplification. | 2.2 | 28 | Citations (PDF) |
| 112 | Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion | 21.4 | 300 | Citations (PDF) |
| 113 | Functional epitopes at the ribosome subunit interface | 9.6 | 30 | Citations (PDF) |
| 114 | Modular approaches to expanding the functions of living matter | 9.6 | 71 | Citations (PDF) |
| 115 | Expanding nucleic acid function and | 4.6 | 5 | Citations (PDF) |
| 116 | Programming and engineering biological networks | 4.8 | 34 | Citations (PDF) |
| 117 | A genetically encoded fluorescent amino acid | 5.3 | 272 | Citations (PDF) |
| 118 | A network of orthogonal ribosome·mRNA pairs | 9.6 | 289 | Citations (PDF) |
| 119 | Cellular Logic with Orthogonal Ribosomes | 12.2 | 81 | Citations (PDF) |
| 120 | Substrate recognition by the AAA+ chaperone ClpB | 6.0 | 229 | Citations (PDF) |
| 121 | Progress Toward an Expanded Eukaryotic Genetic Code | 2.0 | 89 | Citations (PDF) |
| 122 | Adding Amino Acids with Novel Reactivity to the Genetic Code of Saccharomyces Cerevisiae | 12.2 | 391 | Citations (PDF) |
| 123 | Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli | 5.3 | 744 | Citations (PDF) |
| 124 | Addition of p-Azido-l-phenylalanine to the Genetic Code of Escherichia coli | 12.2 | 744 | Citations (PDF) |
| 125 | In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis | 1.9 | 146 | Citations (PDF) |
| 126 | A view to a kill: ligands for Bcl-2 family proteins | 4.6 | 42 | Citations (PDF) |
| 127 | Concerted Evolution of Structure and Function in a Miniature Protein | 12.2 | 98 | Citations (PDF) |
| 128 | Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display | 1.5 | 35 | Citations (PDF) |
| 129 | Design and Evolution of a Miniature Bcl-2 Binding Protein | 0.9 | 16 | Citations (PDF) |
| 130 | Design and Evolution of a Miniature Bcl-2 Binding Protein | 11.8 | 99 | Citations (PDF) |
| 131 | Gene regulation: Protein escorts to the transcription ball | 2.5 | 8 | Citations (PDF) |
| 132 | Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21. | 1.0 | 90 | Citations (PDF) |
| 133 | Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase. | 1.0 | 32 | Citations (PDF) |
| 134 | EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling. | 1.0 | 73 | Citations (PDF) |
| 135 | Discovery and Genetic Code Expansion of a Polyethylene Terephthalate (PET) Hydrolase from the Human Saliva Metagenome for the Degradation and Bio‐Functionalization of PET | 0.9 | 5 | Citations (PDF) |
| 136 | Escherichia coli with a 57-codon genetic code | 26.5 | 37 | Citations (PDF) |
| 137 | High-fidelity human chromosome transfer and elimination | 26.5 | 5 | Citations (PDF) |
| 138 | Highly mutagenic continuous evolution in E. coli using a Φ29-based orthogonal replication system. | 21.4 | 4 | Citations (PDF) |
