390(top 0.1%)
PR articles
166.2K(top 0.1%)
PR citations
167(top 0.1%)
PR h-index
209(top 0.1%)
h-index
486
documents
265.7K
doc citations
8.2K
citing journals
100
times ranked

Publications

402 PR articles • 169,621 PR citations • Sorted by year • Download PDF (PDF by citations)
Sort: Year | Citations
#ArticleIFCitationsLinks
1Taming Lynch Syndrome: The Remarkable Power of Prevention for One Family
Gastroenterology, 2025, 168, 195-199
0.90Citations (PDF)
2Circulating tumor DNA analysis guiding adjuvant therapy in stage II colon cancer: 5-year outcomes of the randomized DYNAMIC trial
Nature Medicine, 2025, 31, 1509-1518
33.045Citations (PDF)
3A Blood-Based Assay for Detection of Patients with Advanced Adenomas2.80Citations (PDF)
4Fragmentation signatures in cancer patients resemble those of patients with vascular or autoimmune diseases7.53Citations (PDF)
5Minimizing and quantifying uncertainty in AI-informed decisions: Applications in medicine7.51Citations (PDF)
6Machine learning to detect the SINEs of cancer12.521Citations (PDF)
7ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
ELife, 2024, 13,
1.61Citations (PDF)
8TRBC1-targeting antibody–drug conjugates for the treatment of T cell cancers
Nature, 2024, 628, 416-423
37.939Citations (PDF)
9Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
ELife, 2024, 13,
1.66Citations (PDF)
10Preclinical studies show that Co-STARs combine the advantages of chimeric antigen and T cell receptors for the treatment of tumors with low antigen densities12.519Citations (PDF)
11The rapid and highly parallel identification of antibodies with defined biological activities by SLISY13.77Citations (PDF)
12Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules7.530Citations (PDF)
13Radiologists' Expectations of Artificial Intelligence in Pancreatic Cancer Imaging: How Good Is Good Enough?1.07Citations (PDF)
14Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen13.724Citations (PDF)
15The Origin of Highly Elevated Cell-Free DNA in Healthy Individuals and Patients with Pancreatic, Colorectal, Lung, or Ovarian Cancer
Cancer Discovery, 2023, 13, 2166-2179
25.1121Citations (PDF)
16TCR-mimic bispecific antibodies to target the HIV-1 reservoir7.519Citations (PDF)
17An isogenic cell line panel for sequence-based screening of targeted anticancer drugs
IScience, 2022, 25, 104437
3.610Citations (PDF)
18Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer
New England Journal of Medicine, 2022, 386, 2261-2272
34.6797Citations (PDF)
19Classification of pancreatic cystic neoplasms using radiomic feature analysis is equivalent to an experienced academic radiologist: a step toward computer-augmented diagnostics for radiologists
Abdominal Radiology, 2022, 47, 4139-4150
1.729Citations (PDF)
20Prognostic significance of postsurgery circulating tumor DNA in nonmetastatic colorectal cancer: Individual patient pooled analysis of three cohort studies
International Journal of Cancer, 2021, 148, 1014-1026
4.399Citations (PDF)
21Association of α1-Blocker Receipt With 30-Day Mortality and Risk of Intensive Care Unit Admission Among Adults Hospitalized With Influenza or Pneumonia in Denmark
JAMA Network Open, 2021, 4, e2037053
6.614Citations (PDF)
22Bispecific antibodies targeting mutantRASneoantigens13.4160Citations (PDF)
23Targeting loss of heterozygosity for cancer-specific immunotherapy7.562Citations (PDF)
24TCR β chain–directed bispecific antibodies for the treatment of T cell cancers12.553Citations (PDF)
25The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-192.429Citations (PDF)
26Targeting a neoantigen derived from a common TP53 mutation
Science, 2021, 371,
36.2321Citations (PDF)
27Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus
Gastroenterology, 2021, 160, 2043-2054.e2
0.929Citations (PDF)
28Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study
PLoS Medicine, 2021, 18, e1003620
8.1159Citations (PDF)
29Detection of low-frequency DNA variants by targeted sequencing of the Watson and Crick strands
Nature Biotechnology, 2021, 39, 1220-1227
29.880Citations (PDF)
30Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers
Nature, 2021, 596, 126-132
37.9451Citations (PDF)
31Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens13.736Citations (PDF)
32Revisiting the tumorigenesis timeline with a data-driven generative model7.555Citations (PDF)
33Assessing aneuploidy with repetitive element sequencing7.575Citations (PDF)
34Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention
Science, 2020, 369,
36.2555Citations (PDF)
35A multimodality test to guide the management of patients with a pancreatic cyst12.5190Citations (PDF)
36p53: a tumor suppressor hiding in plain sight3.514Citations (PDF)
37Circulating Tumor DNA Analyses as Markers of Recurrence Risk and Benefit of Adjuvant Therapy for Stage III Colon Cancer
JAMA Oncology, 2019, 5, 1710
14.4558Citations (PDF)
38Application of Deep Learning to Pancreatic Cancer Detection: Lessons Learned From Our Initial Experience2.381Citations (PDF)
39An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation
Journal of Biological Chemistry, 2019, 294, 19322-19334
2.222Citations (PDF)
40The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with nonspecific findings on standard investigations4.321Citations (PDF)
41An analysis of genetic heterogeneity in untreated cancers
Nature Reviews Cancer, 2019, 19, 639-650
60.8192Citations (PDF)
42Applications of liquid biopsies for cancer12.5185Citations (PDF)
43Direct Detection and Quantification of Neoantigens
Cancer Immunology Research, 2019, 7, 1748-1754
4.263Citations (PDF)
44Cell division rates decrease with age, providing a potential explanation for the age-dependent deceleration in cancer incidence7.582Citations (PDF)
45Prognostic Potential of Circulating Tumor DNA Measurement in Postoperative Surveillance of Nonmetastatic Colorectal Cancer
JAMA Oncology, 2019, 5, 1118
14.4195Citations (PDF)
46Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue4.1173Citations (PDF)
47Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma
Modern Pathology, 2019, 32, 1544-1550
4.860Citations (PDF)
48Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1
2019, 7,
45Citations (PDF)
49Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations
Human Pathology, 2019, 85, 1-9
2.337Citations (PDF)
50Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology2.935Citations (PDF)
51Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)7.558Citations (PDF)
52Deep Learning in Radiology: Now the Real Work Begins2.319Citations (PDF)
53Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers12.5222Citations (PDF)
54Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma13.738Citations (PDF)
55Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome
Nature, 2018, 564, 273-277
37.9250Citations (PDF)
56Precancerous neoplastic cells can move through the pancreatic ductal system
Nature, 2018, 561, 201-205
37.9119Citations (PDF)
57A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts3.535Citations (PDF)
58Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design2.632Citations (PDF)
59Reconstructing metastatic seeding patterns of human cancers13.7135Citations (PDF)
60Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
Nature Genetics, 2017, 49, 358-366
25.2382Citations (PDF)
61Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations7.516Citations (PDF)
62Cancer-Associated Mutations in Endometriosis without Cancer
New England Journal of Medicine, 2017, 376, 1835-1848
34.6560Citations (PDF)
63Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder2.934Citations (PDF)
64Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers7.5534Citations (PDF)
65Selected reaction monitoring approach for validating peptide biomarkers7.537Citations (PDF)
66Necessity Is the Mother of Invention: The Development of Digital Genomics
Clinical Chemistry, 2016, 62, 1668-1669
1.12Citations (PDF)
67High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma2.942Citations (PDF)
68Aristolochic Acid in the Etiology of Renal Cell Carcinoma1.178Citations (PDF)
69Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing7.5221Citations (PDF)
70Evaluating the evaluation of cancer driver genes7.5379Citations (PDF)
71Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer12.51,259Citations (PDF)
72Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer13.7258Citations (PDF)
73Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma
Cancer Cell, 2016, 29, 229-240
33.0166Citations (PDF)
74Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer
Cancer Discovery, 2016, 6, 166-175
25.1334Citations (PDF)
75Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma
Cancer Prevention Research, 2016, 9, 265-274
1.592Citations (PDF)
76Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder
Human Pathology, 2016, 53, 8-13
2.336Citations (PDF)
77High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder
Modern Pathology, 2016, 29, 511-515
4.838Citations (PDF)
78Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease−Associated Colorectal Cancers
Gastroenterology, 2016, 150, 931-943
0.9253Citations (PDF)
79Deregulation of energy metabolism promotes antifibrotic effects in human hepatic stellate cells and prevents liver fibrosis in a mouse model2.135Citations (PDF)
80PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
New England Journal of Medicine, 2015, 372, 2509-2520
34.68,849Citations (PDF)
81Very Long-term Survival Following Resection for Pancreatic Cancer Is Not Explained by Commonly Mutated Genes: Results of Whole-Exome Sequencing Analysis
Clinical Cancer Research, 2015, 21, 1944-1950
6.892Citations (PDF)
82Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes7.559Citations (PDF)
83A Combination of Molecular Markers and Clinical Features Improve the Classification of Pancreatic Cysts
Gastroenterology, 2015, 149, 1501-1510
0.9435Citations (PDF)
84Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas12.5450Citations (PDF)
85Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord7.5397Citations (PDF)
86Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy
ACS Nano, 2015, 9, 6861-6871
15.3141Citations (PDF)
87Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers
Genes and Development, 2015, 29, 2219-2224
4.6191Citations (PDF)
88Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution
Genome Research, 2015, 25, 1536-1545
4.6136Citations (PDF)
89A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
Nature, 2015, 525, 261-264
37.9503Citations (PDF)
90Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study
Journal of Clinical Oncology, 2015, 33, 4293-4300
16.9107Citations (PDF)
91Only three driver gene mutations are required for the development of lung and colorectal cancers7.5378Citations (PDF)
92Intraductal papillary mucinous neoplasm in a neonate with congenital hyperinsulinism and a de novo germline SKIL gene mutation
Pancreatology, 2015, 15, 194-196
0.79Citations (PDF)
93The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Cancer Discovery, 2015, 5, 43-51
25.11,374Citations (PDF)
94Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke
Head and Neck, 2015, 37, 1642-1649
2.074Citations (PDF)
95Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies12.54,369Citations (PDF)
96Remote loading of preencapsulated drugs into stealth liposomes7.5131Citations (PDF)
97Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas3.0100Citations (PDF)
98Whole‐exome sequencing of pancreatic neoplasms with acinar differentiation
Journal of Pathology, 2014, 232, 428-435
4.9172Citations (PDF)
99Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells7.5654Citations (PDF)
100Microbiota organization is a distinct feature of proximal colorectal cancers7.5661Citations (PDF)
101GNAS Sequencing Identifies IPMN-specific Mutations in a Subgroup of Diminutive Pancreatic Cysts Referred to as “Incipient IPMNs”3.558Citations (PDF)
102Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer
Obstetrics and Gynecology, 2014, 124, 881-885
1.951Citations (PDF)
103Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses12.5351Citations (PDF)
104A diaCEST MRI approach for monitoring liposomal accumulation in tumors11.057Citations (PDF)
105Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer
Science, 2014, 343, 152-157
36.2404Citations (PDF)
106Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
Clinical Cancer Research, 2014, 20, 6406-6417
6.856Citations (PDF)
107Activation of diverse signalling pathways by oncogenic PIK3CA mutations13.784Citations (PDF)
108Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors
Nature Genetics, 2014, 46, 1170-1172
25.2284Citations (PDF)
109The Early Detection of Pancreatic Cancer: What Will It Take to Diagnose and Treat Curable Pancreatic Neoplasia?
Cancer Research, 2014, 74, 3381-3389
3.8234Citations (PDF)
110Familial and sporadic pancreatic cancer share the same molecular pathogenesis
Familial Cancer, 2014, 14, 95-103
1.459Citations (PDF)
111Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma
Journal of Neuro-Oncology, 2013, 114, 275-279
2.55Citations (PDF)
112Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas
Annals of Surgical Oncology, 2013, 20, 3802-3808
2.3171Citations (PDF)
113Cancer Genome Landscapes
Science, 2013, 339, 1546-1558
36.27,297Citations (PDF)
114A nanoparticle formulation that selectively transfects metastatic tumors in mice7.568Citations (PDF)
115Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
Nature Genetics, 2013, 45, 1470-1473
25.2617Citations (PDF)
116Mutational Signature of Aristolochic Acid Exposure as Revealed by Whole-Exome Sequencing12.5247Citations (PDF)
117TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal7.51,325Citations (PDF)
118Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers12.5297Citations (PDF)
119Exomic Sequencing of Medullary Thyroid Cancer Reveals Dominant and Mutually Exclusive Oncogenic Mutations in RET and RAS4.1245Citations (PDF)
120Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation7.5374Citations (PDF)
121Noninvasive imaging of infection after treatment with tumor‐homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI
Magnetic Resonance in Medicine, 2013, 70, 1690-1698
2.846Citations (PDF)
122ATM Mutations in Patients with Hereditary Pancreatic Cancer
Cancer Discovery, 2012, 2, 41-46
25.1473Citations (PDF)
123Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis
Biochemical Journal, 2012, 444, 529-535
3.827Citations (PDF)
124Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
PLoS Genetics, 2012, 8, e1002772
3.2567Citations (PDF)
125Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes
Molecular Cancer Research, 2012, 10, 739-749
3.118Citations (PDF)
126Response to Comments on “The Predictive Capacity of Personal Genome Sequencing”12.51Citations (PDF)
127Comparative Genomic Analysis of Esophageal Adenocarcinoma and Squamous Cell Carcinoma
Cancer Discovery, 2012, 2, 899-905
25.1360Citations (PDF)
128Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing12.5594Citations (PDF)
129GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct
Hpb, 2012, 14, 677-683
0.351Citations (PDF)
130Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia
Gastroenterology, 2012, 142, 730-733.e9
0.9670Citations (PDF)
131Low‐grade serous carcinomas of the ovary contain very few point mutations
Journal of Pathology, 2012, 226, 413-420
4.9203Citations (PDF)
132The Predictive Capacity of Personal Genome Sequencing12.5173Citations (PDF)
133Next-Generation Stool DNA Test Accurately Detects Colorectal Cancer and Large Adenomas
Gastroenterology, 2012, 142, 248-256
0.9295Citations (PDF)
134The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
Nature, 2012, 486, 537-540
37.91,600Citations (PDF)
135Genetically Defined Subsets of Human Pancreatic Cancer Show Unique In Vitro Chemosensitivity
Clinical Cancer Research, 2012, 18, 6519-6530
6.866Citations (PDF)
136Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma
Nature Genetics, 2012, 45, 12-17
25.2410Citations (PDF)
137FAST-SeqS: A Simple and Efficient Method for the Detection of Aneuploidy by Massively Parallel Sequencing
PLoS ONE, 2012, 7, e41162
2.373Citations (PDF)
138Mutant proteins as cancer-specific biomarkers7.5171Citations (PDF)
139Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
Nature Genetics, 2011, 43, 828-829
25.2407Citations (PDF)
140The Genetic Landscape of the Childhood Cancer Medulloblastoma
Science, 2011, 331, 435-439
36.2683Citations (PDF)
141Detection and quantification of rare mutations with massively parallel sequencing7.51,150Citations (PDF)
142Thiazolidinedione‐Based PI3Kα Inhibitors: An Analysis of Biochemical and Virtual Screening Methods
ChemMedChem, 2011, 6, 514-522
3.115Citations (PDF)
143Detection of Tumor DNA at the Margins of Colorectal Cancer Liver Metastasis
Clinical Cancer Research, 2011, 17, 3551-3557
6.844Citations (PDF)
144Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome7.5420Citations (PDF)
145Recurrent GNAS Mutations Define an Unexpected Pathway for Pancreatic Cyst Development12.5748Citations (PDF)
14614-3-3σ regulates B-cell homeostasis through stabilization of FOXO17.536Citations (PDF)
147Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways7.5618Citations (PDF)
148The Temporal Order of Genetic and Pathway Alterations in Tumorigenesis
PLoS ONE, 2011, 6, e27136
2.3104Citations (PDF)
149Somatic mutations in PI3Kα: Structural basis for enzyme activation and drug design2.019Citations (PDF)
150Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations
Oncogene, 2010, 29, 2337-2345
6.555Citations (PDF)
151Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
Nature, 2010, 464, 610-614
37.9494Citations (PDF)
152Distant metastasis occurs late during the genetic evolution of pancreatic cancer
Nature, 2010, 467, 1114-1117
37.92,329Citations (PDF)
153Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing12.5468Citations (PDF)
154Genetic inactivation of AKT1 , AKT2 , and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation7.5121Citations (PDF)
155Accumulation of driver and passenger mutations during tumor progression7.5803Citations (PDF)
156Patient-oriented gene set analysis for cancer mutation data
Genome Biology, 2010, 11,
8.166Citations (PDF)
157Identification of Somatically Acquired Gene Mutations In the Kineome and Exome In CLL
Blood, 2010, 116, 2410-2410
4.20Citations (PDF)
158A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane7.5290Citations (PDF)
159Inactivating germ-line and somatic mutations in polypeptide N -acetylgalactosaminyltransferase 12 in human colon cancers7.5137Citations (PDF)
160A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p537.5286Citations (PDF)
161Sensitive digital quantification of DNA methylation in clinical samples
Nature Biotechnology, 2009, 27, 858-863
29.8334Citations (PDF)
162Design and analysis issues in genome-wide somatic mutation studies of cancer
Genomics, 2009, 93, 17-21
2.886Citations (PDF)
163IDH1 and IDH2 Mutations in Gliomas34.65,815Citations (PDF)
164Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations
Cancer Research, 2009, 69, 6660-6667
3.8445Citations (PDF)
165Structural comparisons of class I phosphoinositide 3-kinases
Nature Reviews Cancer, 2008, 8, 665-669
60.898Citations (PDF)
166Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q
BMC Cancer, 2008, 8,
2.935Citations (PDF)
167Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients
Gastroenterology, 2008, 135, 489-498.e7
0.9216Citations (PDF)
168Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers7.5382Citations (PDF)
169Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers7.5300Citations (PDF)
170Comparative lesion sequencing provides insights into tumor evolution7.5773Citations (PDF)
171Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket
Biochemical Journal, 2008, 414, 383-390
3.851Citations (PDF)
172Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T7.5202Citations (PDF)
173Genetic Progression and the Waiting Time to Cancer3.1352Citations (PDF)
174Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics4.6202Citations (PDF)
175Spore Coat Architecture of Clostridium novyi NT Spores
Journal of Bacteriology, 2007, 189, 6457-6468
2.948Citations (PDF)
176A multidimensional analysis of genes mutated in breast and colorectal cancers
Genome Research, 2007, 17, 1304-1318
4.6121Citations (PDF)
177Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumours
European Journal of Cancer, 2007, 43, 490-496
4.9100Citations (PDF)
178Imaging of Musculoskeletal Bacterial Infections by [124I]FIAU-PET/CT
PLoS ONE, 2007, 2, e1007
2.391Citations (PDF)
179Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of DMXAA in human and mouse plasma2.62Citations (PDF)
180The role of companion diagnostics in the development and use of mutation-targeted cancer therapies
Nature Biotechnology, 2006, 24, 985-995
29.8132Citations (PDF)
181The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT
Nature Biotechnology, 2006, 24, 1573-1580
29.8147Citations (PDF)
182BEAMing up for detection and quantification of rare sequence variants
Nature Methods, 2006, 3, 95-97
24.6264Citations (PDF)
183Somatic mutations ofGUCY2F,EPHA3, andNTRK3 in human cancers
Human Mutation, 2006, 27, 1060-1061
4.590Citations (PDF)
184Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors7.5141Citations (PDF)
185The colorectal microRNAome7.5902Citations (PDF)
186Discodermolide analogues as the chemical component of combination bacteriolytic therapy2.034Citations (PDF)
187Contribution of bone marrow–derived endothelial cells to human tumor vasculature
Nature Medicine, 2005, 11, 261-262
33.0475Citations (PDF)
188Mutations in a signalling pathway
Nature, 2005, 436, 792-792
37.9525Citations (PDF)
189Mutant PIK3CA promotes cell growth and invasion of human cancer cells
Cancer Cell, 2005, 7, 561-573
33.0872Citations (PDF)
190Can chromosomal instability initiate tumorigenesis?13.7183Citations (PDF)
191Detection and quantification of mutations in the plasma of patients with colorectal tumors7.51,118Citations (PDF)
192Pharmacologic and Toxicologic Evaluation of C. novyi-NT Spores
Toxicological Sciences, 2005, 88, 562-575
3.8104Citations (PDF)
193Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro- -D-arabinofuranosyl)-5-iodouracil7.5128Citations (PDF)
194Targeting Vascular and Avascular Compartments of Tumors withC. novyi-NTand Anti-microtubule Agents
Cancer Biology and Therapy, 2004, 3, 326-337
4.1100Citations (PDF)
195Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses
Nucleic Acids Research, 2004, 32, 3e-3
15.5149Citations (PDF)
196SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells7.573Citations (PDF)
197Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients7.5180Citations (PDF)
198Bacteriolytic therapy can generate a potent immune response against experimental tumors7.5278Citations (PDF)
199Cancer genes and the pathways they control
Nature Medicine, 2004, 10, 789-799
33.03,871Citations (PDF)
200Inactivation of hCDC4 can cause chromosomal instability
Nature, 2004, 428, 77-81
37.9524Citations (PDF)
201Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase2.012Citations (PDF)
202Somatic Mutations of EGFR in Colorectal Cancers and Glioblastomas
New England Journal of Medicine, 2004, 351, 2883-2883
34.6296Citations (PDF)
203Knudson's hypothesis and theTP53 revolution
Genes Chromosomes and Cancer, 2003, 38, 329-329
3.011Citations (PDF)
204Design, synthesis and evaluation of new RDP inhibitors
Tetrahedron Letters, 2003, 44, 1871-1873
1.413Citations (PDF)
205Multicolor in vitro translation
Nature Biotechnology, 2003, 21, 1093-1097
29.827Citations (PDF)
206The significance of unstable chromosomes in colorectal cancer
Nature Reviews Cancer, 2003, 3, 695-701
60.8432Citations (PDF)
207Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations7.5786Citations (PDF)
208Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria7.5161Citations (PDF)
209PUMA mediates the apoptotic response to p53 in colorectal cancer cells7.5550Citations (PDF)
210The Chk2 Tumor Suppressor Is Not Required for p53 Responses in Human Cancer Cells
Journal of Biological Chemistry, 2003, 278, 20475-20479
2.2135Citations (PDF)
211The role of chromosomal instability in tumor initiation7.5506Citations (PDF)
212Digital karyotyping7.5218Citations (PDF)
213Targeted inactivation of CTNNB1 reveals unexpected effects of  -catenin mutation7.5124Citations (PDF)
214DEC1 is a downstream target of TGF-  with sequence-specific transcriptional repressor activities7.586Citations (PDF)
215GENETICS: Please Don't Call It Cloning!
Science, 2002, 295, 1237-1237
36.263Citations (PDF)
216Dynamics of Genetic Instability in Sporadic and Familial Colorectal Cancer
Cancer Biology and Therapy, 2002, 1, 685-692
4.169Citations (PDF)
217Detection of APC Mutations in Fecal DNA from Patients with Colorectal Tumors34.6328Citations (PDF)
218Prevalence of somatic alterations in the colorectal cancer cell genome7.5176Citations (PDF)
219Counting alleles to predict recurrence of early-stage colorectal cancers
Lancet, The, 2002, 359, 219-225
62.3143Citations (PDF)
220Detection of proximal colorectal cancers through analysis of faecal DNA
Lancet, The, 2002, 359, 403-404
62.3142Citations (PDF)
221DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
Nature, 2002, 416, 552-556
37.91,165Citations (PDF)
222RAF/RAS oncogenes and mismatch-repair status
Nature, 2002, 418, 934-934
37.91,152Citations (PDF)
223PUMA Induces the Rapid Apoptosis of Colorectal Cancer Cells
Molecular Cell, 2001, 7, 673-682
13.31,196Citations (PDF)
224Securin Is Required for Chromosomal Stability in Human Cells
Cell, 2001, 105, 445-457
33.7380Citations (PDF)
225Combination bacteriolytic therapy for the treatment of experimental tumors7.5524Citations (PDF)
226Mutation Screening of the TNFRSF11A Gene Encoding Receptor Activator of NFkB (RANK) in Familial and Sporadic Paget's Disease of Bone and Osteosarcoma2.876Citations (PDF)
227Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
Nature Genetics, 2001, 28, 184-187
25.2604Citations (PDF)
228Use of isogenic human cancer cells for high-throughput screening and drug discovery
Nature Biotechnology, 2001, 19, 940-945
29.8247Citations (PDF)
229Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells
Nature Medicine, 2001, 7, 1111-1117
33.0410Citations (PDF)
230Detecting Colorectal Cancer in Stool With the Use of Multiple Genetic Targets4.6561Citations (PDF)
231Genetic disruption of PPAR  decreases the tumorigenicity of human colon cancer cells7.5243Citations (PDF)
232Mechanisms underlying losses of heterozygosity in human colorectal cancers7.5206Citations (PDF)
233Top-down morphogenesis of colorectal tumors7.5337Citations (PDF)
234Carcinogen-specific induction of genetic instability7.5155Citations (PDF)
235Small changes in expression affect predisposition to tumorigenesis
Nature Genetics, 2001, 30, 25-26
25.2237Citations (PDF)
236Combinatorial chemoprevention of intestinal neoplasia
Nature Medicine, 2000, 6, 1024-1028
33.0507Citations (PDF)
237Conversion of diploidy to haploidy
Nature, 2000, 403, 723-724
37.9249Citations (PDF)
238CpG methylation is maintained in human cancer cells lacking DNMT1
Nature, 2000, 404, 1003-1007
37.9424Citations (PDF)
239p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest
Cancer Letters, 2000, 156, 63-72
8.679Citations (PDF)
240Cooperative effects of genes controlling the G2/M checkpoint
Genes and Development, 2000, 14, 1584-1588
4.6228Citations (PDF)
241Going Mad withSmads
New England Journal of Medicine, 1999, 341, 1144-1146
34.648Citations (PDF)
242Analysis of masked mutations in familial adenomatous polyposis7.5110Citations (PDF)
243Identification and classification of p53-regulated genes7.5428Citations (PDF)
24414-3-3σ is required to prevent mitotic catastrophe after DNA damage
Nature, 1999, 401, 616-620
37.9896Citations (PDF)
245Analysis of human transcriptomes
Nature Genetics, 1999, 23, 387-388
25.2746Citations (PDF)
246Genetic instability and darwinian selection in tumours
Trends in Genetics, 1999, 15, M57-M60
9.830Citations (PDF)
247Genetic instability and darwinian selection in tumours
Trends in Cell Biology, 1999, 9, M57-M60
12.1655Citations (PDF)
248Genetic instability and darwinian selection in tumours6.720Citations (PDF)
249Digital PCR7.51,660Citations (PDF)
250PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
Cell, 1999, 99, 335-345
33.71,078Citations (PDF)
251Characterization of MAD2B and Other Mitotic Spindle Checkpoint Genes
Genomics, 1999, 58, 181-187
2.8216Citations (PDF)
252Disruption of p53 in human cancer cells alters the responses to therapeutic agents10.6950Citations (PDF)
253Somatic mutations of the mitochondrial genome in human colorectal tumours
Nature Genetics, 1998, 20, 291-293
25.2809Citations (PDF)
254Mutations of mitotic checkpoint genes in human cancers
Nature, 1998, 392, 300-303
37.91,430Citations (PDF)
255Genetic instabilities in human cancers
Nature, 1998, 396, 643-649
37.93,960Citations (PDF)
256Genotyping by mass spectrometric analysis of short DNA fragments
Nature Biotechnology, 1998, 16, 1352-1356
29.8112Citations (PDF)
257Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators
Molecular Cell, 1998, 1, 611-617
13.3975Citations (PDF)
258Characterization of Human FAST-1, a TGFβ and Activin Signal Transducer
Molecular Cell, 1998, 2, 121-127
13.3229Citations (PDF)
259Accumulated Clonal Genetic Alterations in Familial and Sporadic Colorectal Carcinomas with Widespread Instability in Microsatellite Sequences
American Journal of Pathology, 1998, 153, 1063-1078
3.4183Citations (PDF)
260Targeted deletion of Smad4 shows it is required for transforming growth factor   and activin signaling in colorectal cancer cells7.5152Citations (PDF)
261A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype
Molecular and Cellular Biology, 1998, 18, 1635-1641
2.597Citations (PDF)
262Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma7.51,761Citations (PDF)
263A simplified system for generating recombinant adenoviruses7.53,369Citations (PDF)
264Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis7.5560Citations (PDF)
265Cancer risk associated with germline DNA mismatch repair gene mutations
Human Molecular Genetics, 1997, 6, 105-110
2.9613Citations (PDF)
266DNA methylation and genetic instability in colorectal cancer cells7.5366Citations (PDF)
267Is a p53-Regulated Inhibitor of G2/M Progression
Molecular Cell, 1997, 1, 3-11
13.31,184Citations (PDF)
268Characterization of the Yeast Transcriptome
Cell, 1997, 88, 243-251
33.71,044Citations (PDF)
269Less death in the dying13.315Citations (PDF)
270Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC
Nature Genetics, 1997, 17, 79-83
25.2653Citations (PDF)
271Cell-cycle arrest versus cell death in cancer therapy
Nature Medicine, 1997, 3, 1034-1036
33.0359Citations (PDF)
272A model for p53-induced apoptosis
Nature, 1997, 389, 300-305
37.92,445Citations (PDF)
273Genetic instability in colorectal cancers
Nature, 1997, 386, 623-627
37.91,854Citations (PDF)
274Molecular Cloning of the N-Terminus of GTBP
Genomics, 1996, 31, 395-397
2.833Citations (PDF)
275Lessons from Hereditary Colorectal Cancer
Cell, 1996, 87, 159-170
33.74,483Citations (PDF)
276Nomenclature: Vertebrate Mediators of TGFβ Family Signals
Cell, 1996, 87, 173
33.7179Citations (PDF)
277Converting cancer genes into killer genes.7.547Citations (PDF)
278Mammalian cells resistant to tumor suppressor genes.7.59Citations (PDF)
279Expression of p21waf1/cip1 , mdm2 and p53 in vivo : analysis of cytological preparations
Cytopathology, 1996, 7, 340-351
1.05Citations (PDF)
280Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
Nature Genetics, 1996, 13, 343-346
25.2592Citations (PDF)
281Mad-related genes in the human
Nature Genetics, 1996, 13, 347-349
25.2361Citations (PDF)
282Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
Nature, 1996, 381, 713-716
37.9735Citations (PDF)
283SHORT COMMUNICATION: Sulindac suppresses tumorigenesis in the Min mouse
Carcinogenesis, 1996, 17, 1757-1760
2.8172Citations (PDF)
284PAK1, a gene that can regulate p53 activity in yeast.7.526Citations (PDF)
285Polymerase δ variants in RER colorectal tumours
Nature Genetics, 1995, 9, 10-11
25.2131Citations (PDF)
286Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
Nature Genetics, 1995, 9, 48-55
25.2775Citations (PDF)
287Monoallelic mutation analysis (MAMA) for identifying germline mutations
Nature Genetics, 1995, 11, 99-102
25.270Citations (PDF)
288Genetic instability occurs in the majority of young patients with colorectal cancer
Nature Medicine, 1995, 1, 348-352
33.0360Citations (PDF)
289Founding mutations and Alu-mediated recombination in hereditary colon cancer
Nature Medicine, 1995, 1, 1203-1206
33.0280Citations (PDF)
290Genomic Organization of the HumanPMS2Gene Family
Genomics, 1995, 30, 195-206
2.8121Citations (PDF)
291Analysis of the 5′ Region ofPMS2Reveals Heterogeneous Transcripts and a Novel Overlapping Gene
Genomics, 1995, 29, 329-334
2.841Citations (PDF)
292The Molecular Basis of Turcot's Syndrome34.61,094Citations (PDF)
293Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer34.6697Citations (PDF)
294An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
Journal of Pathology, 1994, 172, 5-12
4.9503Citations (PDF)
295Lack of association of human polyomaviruses with human brain tumors
Journal of Neuro-Oncology, 1994, 20, 55-58
2.556Citations (PDF)
296Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer
Nature, 1994, 371, 75-80
37.91,561Citations (PDF)
297Cancer Therapy Meets p5334.679Citations (PDF)
298Has the breast cancer gene been found?
Cell, 1994, 79, 1-3
33.7113Citations (PDF)
299The DCC Gene: Structural Analysis and Mutations in Colorectal Carcinomas
Genomics, 1994, 19, 525-531
2.8217Citations (PDF)
300p53 tagged sites from human genomic DNA
Human Molecular Genetics, 1994, 3, 1537-1542
2.9177Citations (PDF)
301Sequence-specific transcriptional activation is essential for growth suppression by p53.7.5371Citations (PDF)
302Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.7.5277Citations (PDF)
303Colorectal Cancer and the Intersection between Basic and Clinical Research1.627Citations (PDF)
304Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
Nature, 1993, 362, 857-860
37.91,437Citations (PDF)
305The multistep nature of cancer
Trends in Genetics, 1993, 9, 138-141
9.81,687Citations (PDF)
306Cell adhesion molecules as tumour suppressors
Trends in Cell Biology, 1993, 3, 36-39
12.188Citations (PDF)
307Mapping of Multiple Intestinal Neoplasia (Min) to Proximal Chromosome 18 of the Mouse
Genomics, 1993, 15, 3-8
2.853Citations (PDF)
308WAF1, a potential mediator of p53 tumor suppression
Cell, 1993, 75, 817-825
33.78,296Citations (PDF)
309Molecular Diagnosis of Familial Adenomatous Polyposis
New England Journal of Medicine, 1993, 329, 1982-1987
34.6672Citations (PDF)
310In vivocloning of PCR products inE.coli
Nucleic Acids Research, 1993, 21, 5192-5197
15.5122Citations (PDF)
311Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
Cell, 1993, 75, 1215-1225
33.72,239Citations (PDF)
312Hypermutability and mismatch repair deficiency in RER+ tumor cells
Cell, 1993, 75, 1227-1236
33.71,059Citations (PDF)
313The APC gene product in normal and tumor cells.7.5394Citations (PDF)
314SAM 1.1 and JOSH 4.4: two RFLPs within the human DCC gene
Human Molecular Genetics, 1992, 1, 352-352
2.99Citations (PDF)
315The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma
Gastroenterology, 1992, 102, 1612-1619
0.9114Citations (PDF)
316The Colorectal Cancer Gene Hunt: Current Findings
Hospital Practice (1995), 1992, 27, 51-58
1.014Citations (PDF)
317Structural alterations of the epidermal growth factor receptor gene in human gliomas.7.5795Citations (PDF)
318Clonal Origin of Bladder Cancer34.6511Citations (PDF)
319A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18
Genomics, 1992, 13, 1281-1288
2.846Citations (PDF)
320p53 function and dysfunction
Cell, 1992, 70, 523-526
33.72,222Citations (PDF)
321A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
Cell, 1992, 71, 587-597
33.73,044Citations (PDF)
322Clonal expansion of p53 mutant cells is associated with brain tumour progression
Nature, 1992, 355, 846-847
37.9638Citations (PDF)
323Amplification of a gene encoding a p53-associated protein in human sarcomas
Nature, 1992, 358, 80-83
37.91,985Citations (PDF)
324APC mutations occur early during colorectal tumorigenesis
Nature, 1992, 359, 235-237
37.91,782Citations (PDF)
325Insertion/Deletion Polymorphism and Other Restriction Fragment Length Polymorphisms in theMCCGene1.84Citations (PDF)
326Definition of a consensus binding site for p53
Nature Genetics, 1992, 1, 45-49
25.21,987Citations (PDF)
327Suppressor gene alterations in the colorectal adenoma-carcinoma sequence3.068Citations (PDF)
328Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients
Human Mutation, 1992, 1, 467-473
4.5115Citations (PDF)
329Investigation of colon cancers for human papillomavirus genomic sequences by polymerase chain reaction1.544Citations (PDF)
330Colon cancer genetics
Cancer, 1992, 70, 1300-1312
4.052Citations (PDF)
331Genetic alterations in the adenoma–carcinoma sequence
Cancer, 1992, 70, 1727-1731
4.0324Citations (PDF)
332Human p53 and CDC2Hs Genes Combine To Inhibit the Proliferation of Saccharomyces cerevisiae
Molecular and Cellular Biology, 1992, 12, 1357-1365
2.550Citations (PDF)
333Progression of Colorectal Cancer Is Associated with Multiple Tumor Suppressor Gene Defects but Inhibition of Tumorigenicity Is Accomplished by Correction of Any Single Defect via Chromosome Transfer
Molecular and Cellular Biology, 1992, 12, 1387-1395
2.576Citations (PDF)
334Isolation and Structural Analysis of a 1.2-Megabase N-myc Amplicon from a Human Neuroblastoma
Molecular and Cellular Biology, 1992, 12, 5563-5570
2.524Citations (PDF)
335Scrambled exons
Cell, 1991, 64, 607-613
33.7923Citations (PDF)
336Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication
Cell, 1991, 65, 1083-1091
33.7409Citations (PDF)
337Immunogenicity of a non-class I MHC expressing murine tumor transfected with the influenza virus hemagglutinin or murine interleukin-2 genes4.64Citations (PDF)
338HindIIIpolymorphism in the DCC gene
Nucleic Acids Research, 1991, 19, 6965-6965
15.52Citations (PDF)
339The Zinc Finger Protein GLI Transforms Primary Cells in Cooperation with Adenovirus E1A
Molecular and Cellular Biology, 1991, 11, 1724-1728
2.549Citations (PDF)
340EcoRI polymorphism within theGLIgene (chromosome 12q13.3–14.1)
Nucleic Acids Research, 1990, 18, 2834-2834
15.59Citations (PDF)
341RAS gene mutations in childhood acute myeloid leukemia: A pediatric oncology group study3.045Citations (PDF)
342Cytogenetics and Molecular Genetics of Malignant Gliomas and Medulloblastoma
Brain Pathology, 1990, 1, 12-18
5.0149Citations (PDF)
343Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response
Cell, 1990, 60, 397-403
33.7935Citations (PDF)
344A genetic model for colorectal tumorigenesis
Cell, 1990, 61, 759-767
33.711,373Citations (PDF)
345GLI3 Encodes a 190-Kilodalton Protein with Multiple Regions of GLI Similarity
Molecular and Cellular Biology, 1990, 10, 5408-5415
2.569Citations (PDF)
346p53 Functions as a Cell Cycle Control Protein in Osteosarcomas
Molecular and Cellular Biology, 1990, 10, 5772-5781
2.5324Citations (PDF)
347The GLI Gene Encodes a Nuclear Protein Which Binds Specific Sequences in the Human Genome2.5241Citations (PDF)
348Allelic Loss in Colorectal Carcinoma16.6263Citations (PDF)
349Whole genome PCR: application to the identification of sequences bound by gene regulatory protein
Nucleic Acids Research, 1989, 17, 3645-3653
15.5196Citations (PDF)
350Systemic immunity against a murine colon tumor (CT-26) produced by immunization with syngeneic cells expressing a transfected viral gene product4.324Citations (PDF)
351Mutations in the p53 gene occur in diverse human tumour types
Nature, 1989, 342, 705-708
37.92,751Citations (PDF)
352The GLI gene is a member of the Kruppel family of zinc finger proteins
Nature, 1988, 332, 371-374
37.9386Citations (PDF)
353Genetic Alterations during Colorectal-Tumor Development34.66,376Citations (PDF)
354Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects1.8183Citations (PDF)
355Carrier detection in the Wiskott Aldrich syndrome
Blood, 1988, 72, 1735-1739
4.2103Citations (PDF)
356The GLI-Kruppel Family of Human Genes
Molecular and Cellular Biology, 1988, 8, 3104-3113
2.5130Citations (PDF)
357Characterization of N-myc Amplification Units in Human Neuroblastoma Cells2.512Citations (PDF)
358Carrier Detection in X-Linked Agammaglobulinemia by Analysis of X-Chromosome Inactivation34.6165Citations (PDF)
359Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.7.5777Citations (PDF)
360Relationship between gene amplification and chromosomal deviations in malignant human gliomas1.2126Citations (PDF)
361Alterations in DNA methylation in human colon neoplasia2.050Citations (PDF)
362Rapid purification of DNA from agarose gels by centrifugation through a disposable plastic column
Analytical Biochemistry, 1987, 160, 115-118
2.429Citations (PDF)
363Prevalence of ras gene mutations in human colorectal cancers
Nature, 1987, 327, 293-297
37.91,780Citations (PDF)
364Gene amplification in cancer: A molecular cytogenetic approach1.213Citations (PDF)
365Differentiation of Leukemia Cells to Polymorphonuclear Leukocytes in Patients with Acute Nonlymphocytic Leukemia34.6296Citations (PDF)
366Loss of genes on the short arm of chromosome 11 in bladder cancer
Nature, 1985, 318, 377-380
37.9335Citations (PDF)
367Supercoiled loops and the organization of replication and transcription in eukaryotes
BioEssays, 1985, 2, 52-54
2.157Citations (PDF)
368The anatomy of supercoiled loops in theDrosophila, 7F locus
Nucleic Acids Research, 1985, 13, 7703-7713
15.524Citations (PDF)
369The association of transcribed genes with the nuclear matrix ofDrosophilacells during heat shock
Nucleic Acids Research, 1985, 13, 2413-2431
15.5122Citations (PDF)
370Purification of DNA from formaldehyde fixed and paraffin embedded human tissue2.1793Citations (PDF)
371Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours
Nature, 1984, 309, 176-178
37.9427Citations (PDF)
372Hypomethylation distinguishes genes of some human cancers from their normal counterparts
Nature, 1983, 301, 89-92
37.92,285Citations (PDF)
373A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Analytical Biochemistry, 1983, 132, 6-13
2.424,606Citations (PDF)
374Hypomethylation of ras oncogenes in primary human cancers2.1480Citations (PDF)
375The association of transcriptionally active genes with the nuclear matrix of the chicken oviduct
Nucleic Acids Research, 1983, 11, 5113-5130
15.5146Citations (PDF)
376The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells
Cell, 1982, 28, 99-106
33.7378Citations (PDF)
377A subset of small nuclear ribonucleoprotein particle antigens is a component of the nuclear matrix2.140Citations (PDF)
378Increased phosphorylation rate of intermediate filaments during mitotic arrest
Experimental Cell Research, 1981, 133, 445-449
3.121Citations (PDF)
379Association of newly replicated DNA with the nuclear matrix of Physarum polycephalum
Nucleic Acids Research, 1981, 9, 349-363
15.565Citations (PDF)
380Localization of SV40 genes within supercoiled loop domains
Nucleic Acids Research, 1980, 8, 5623-5633
15.5112Citations (PDF)
381Sequence analysis of nuclear matrix associated DNA from rat liver
Experimental Cell Research, 1980, 128, 466-470
3.181Citations (PDF)
382A fixed site of DNA replication in eucaryotic cells
Cell, 1980, 19, 527-536
33.7706Citations (PDF)
383Protein factor(s) from mitotic CHO cells induce meiotic maturation in Xenopus laevis oocytes
FEBS Letters, 1980, 109, 233-238
2.796Citations (PDF)
384Supercoiled loops and eucaryotic DNA replication
Cell, 1980, 22, 79-85
33.7623Citations (PDF)
385Divergence of primate ribosomal RNA genes as assayed by restriction enzyme analysis
Gene, 1980, 11, 89-96
2.311Citations (PDF)
386The relationship of the nuclear matrix to cellular structure and function3.5103Citations (PDF)
387Continuous sampling as a pharmacokinetic tool4.715Citations (PDF)
388RNA-DNA hybridization in solution without DNA reannealing2.131Citations (PDF)
389The pharmacokinetics of amikacin in children
Journal of Pediatrics, 1977, 91, 333-339
2.066Citations (PDF)
390Invasive Aspergillosis34.6119Citations (PDF)
391Evolutionary dynamics of cancer in response to targeted combination therapy
ELife, 0, 2,
1.6567Citations (PDF)
392Diagnostic potential of tumor DNA from ovarian cyst fluid
ELife, 0, 5,
1.638Citations (PDF)
393Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
ELife, 0, 7,
1.6145Citations (PDF)
394Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
ELife, 0, 10,
1.616Citations (PDF)
395Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection
ELife, 0, 10,
1.629Citations (PDF)
396Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
ELife, 0, 13,
1.60Citations (PDF)
397ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
ELife, 0, 13,
1.60Citations (PDF)
398Detection of Cancers Three Years prior to Diagnosis Using Plasma Cell-Free DNA
Cancer Discovery, 0, 15, 1794-1802
25.18Citations (PDF)
399Detection of Human Brain Cancers using Genomic and Immune Cell Characterization of Cerebrospinal Fluid through CSF-BAM
Cancer Discovery, 0, 15, 2002-2018
25.11Citations (PDF)
400Circulating tumor DNA-guided adjuvant therapy in locally advanced colon cancer: the randomized phase 2/3 DYNAMIC-III trial
Nature Medicine, 0, 31, 4291-4300
33.06Citations (PDF)
401TRBC2-targeting antibody–drug conjugates for the treatment of T cell cancers
Nature Cancer, 0, 6, 2011-2024
22.51Citations (PDF)
402Bispecific antibodies and CAR T cells targeting a TP53 mutation–associated neoantigen show discordant affinity requirements10.60Citations (PDF)