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319 peer-reviewed articles • 36,463 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Ozanimod, a Functional Sphingosine-1-Phosphate Receptor 1 Antagonist, Attenuates Paclitaxel-Induced Cognitive Impairment (Abstract ID: 166985)3.30Citations (PDF)
2Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
Molecular Metabolism, 2024, 79, 101851
5.96Citations (PDF)
3ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis
Journal of Lipid Research, 2024, 65, 100556
3.67Citations (PDF)
4Sphingosine kinase 2 and p62 regulation are determinants of sexual dimorphism in hepatocellular carcinoma
Molecular Metabolism, 2024, 86, 101971
5.94Citations (PDF)
5FTY720/Fingolimod mitigates paclitaxel‐induced Sparcl1‐driven neuropathic pain and breast cancer progression
FASEB Journal, 2024, 38,
0.618Citations (PDF)
6Dissociation between the anti-allodynic effects of fingolimod (FTY720) and desensitization of S1P1 receptor-mediated G-protein activation in a mouse model of sciatic nerve injury
Neuropharmacology, 2024, 261, 110165
4.33Citations (PDF)
7Preclinical models of non-alcoholic steatohepatitis leading to hepatocellular carcinoma2.03Citations (PDF)
8Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer
Cancer Research, 2023, 83, 553-567
3.818Citations (PDF)
9ORMDL in metabolic health and disease
2023, 245, 108401
13Citations (PDF)
10Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function2.268Citations (PDF)
11Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells
PLoS Pathogens, 2023, 19, e1011842
4.49Citations (PDF)
12Neuronal contact upregulates astrocytic sphingosine‐1‐phosphate receptor 1 to coordinate astrocyte‐neuron cross communication
Glia, 2022, 70, 712-727
5.040Citations (PDF)
13A new preclinical model of western diet‐induced progression of non‐alcoholic steatohepatitis to hepatocellular carcinoma
FASEB Journal, 2022, 36,
0.633Citations (PDF)
14Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH
Molecular Metabolism, 2022, 62, 101523
5.917Citations (PDF)
15Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment10.642Citations (PDF)
16Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking7.520Citations (PDF)
17Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma6.177Citations (PDF)
18Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα‐dependent inflammation and apoptosis
FASEB Journal, 2021, 35,
0.617Citations (PDF)
19Dye-free spectrophotometric measurement of nucleic acid-to-protein ratio for cell-selective extracellular vesicle discrimination9.615Citations (PDF)
20Diacylglycerol Lipase-β Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences3.13Citations (PDF)
21Sphingolipids in metabolic disease: The good, the bad, and the unknown
Cell Metabolism, 2021, 33, 1293-1306
25.2298Citations (PDF)
22CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism
Journal of Lipid Research, 2021, 62, 100082
3.632Citations (PDF)
23Sphingosine-1-phosphate signaling: A novel target for simultaneous adjuvant treatment of triple negative breast cancer and chemotherapy-induced neuropathic pain2.044Citations (PDF)
24Tumor‐derived exosomes (TDEs): How to avoid the sting in the tail
Medicinal Research Reviews, 2020, 40, 385-412
13.453Citations (PDF)
25Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors
Bioorganic Chemistry, 2020, 94, 103414
4.124Citations (PDF)
26Targeting the Sphingosine-1-Phosphate Axis for Developing Non-narcotic Pain Therapeutics11.452Citations (PDF)
27S1P lyase inhibition protects against sepsis by promoting disease tolerance via the S1P/S1PR3 axis
EBioMedicine, 2020, 58, 102898
9.732Citations (PDF)
28Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents
Pain, 2020, 161, 2107-2118
4.225Citations (PDF)
29Sphingosine-1-phosphate: From insipid lipid to a key regulator
Journal of Biological Chemistry, 2020, 295, 3371-3384
2.218Citations (PDF)
30A simple method for sphingolipid analysis of tissues embedded in optimal cutting temperature compound
Journal of Lipid Research, 2020, 61, 953-967
3.68Citations (PDF)
31Regulatory role of SphK1 in TLR7/9‐dependent type I interferon response and autoimmunity
FASEB Journal, 2020, 34, 4329-4347
0.619Citations (PDF)
32Inflammatory Conditions Disrupt Constitutive Endothelial Cell Barrier Stabilization by Alleviating Autonomous Secretion of Sphingosine 1-Phosphate
Cells, 2020, 9, 928
4.623Citations (PDF)
33Functional analysis of molecular and pharmacological modulators of mitochondrial fatty acid oxidation
Scientific Reports, 2020, 10,
3.462Citations (PDF)
34Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation
Journal of Biological Chemistry, 2020, 295, 9121-9133
2.224Citations (PDF)
35Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells
Journal of Lipid Research, 2019, 60, 1590-1602
3.636Citations (PDF)
36ORMDL3 and allergic asthma: From physiology to pathology6.176Citations (PDF)
37New insights into functions of the sphingosine-1-phosphate transporter SPNS2
Journal of Lipid Research, 2019, 60, 484-489
3.689Citations (PDF)
38FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice
Journal of Lipid Research, 2019, 60, 1311-1322
3.652Citations (PDF)
39Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain7.5123Citations (PDF)
40Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma
Leukemia, 2019, 33, 2884-2897
7.731Citations (PDF)
41Examination of the role of sphingosine kinase 2 in a murine model of systemic lupus erythematosus
FASEB Journal, 2019, 33, 7061-7071
0.614Citations (PDF)
42Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition
Cancer Biology and Therapy, 2019, 20, 597-607
4.114Citations (PDF)
43Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti‐inflammatory activity3.810Citations (PDF)
44The ORMDL3 Asthma Gene Regulates ICAM1 and Has Multiple Effects on Cellular Inflammation8.986Citations (PDF)
45Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis
Cancer Research, 2018, 78, 1713-1725
3.8213Citations (PDF)
46ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer
Molecular Cancer Research, 2018, 16, 1059-1070
3.172Citations (PDF)
47Sphingosine kinase 1 in breast cancer2.041Citations (PDF)
48Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer
Journal of Lipid Research, 2018, 59, 2297-2307
3.637Citations (PDF)
49Niemann-Pick type C disease: The atypical sphingolipidosis2.072Citations (PDF)
50Non-alcoholic fatty liver disease: Insights from sphingolipidomics2.135Citations (PDF)
51Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking
Journal of Biological Chemistry, 2017, 292, 3074-3088
2.277Citations (PDF)
52FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann‐Pick type C mutant fibroblasts
FASEB Journal, 2017, 31, 1719-1730
0.646Citations (PDF)
53Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology6.766Citations (PDF)
54Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation
Pain, 2017, 158, 1733-1742
4.267Citations (PDF)
55Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
Nature, 2017, 541, 233-236
37.9221Citations (PDF)
56An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors5.340Citations (PDF)
57Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods
Heliyon, 2016, 2, e00219
3.237Citations (PDF)
58Sphingosine‐1‐phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans
FASEB Journal, 2016, 30, 2945-2958
0.658Citations (PDF)
59VEGF Potentiates GD3-Mediated Immunosuppression by Human Ovarian Cancer Cells
Clinical Cancer Research, 2016, 22, 4249-4258
6.837Citations (PDF)
60Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods3.147Citations (PDF)
61Host sphingosine kinase 1 worsens pancreatic cancer peritoneal carcinomatosis
Journal of Surgical Research, 2016, 205, 510-517
1.637Citations (PDF)
62Murine model of long-term obstructive jaundice
Journal of Surgical Research, 2016, 206, 118-125
1.626Citations (PDF)
63Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure
Journal of Pathology, 2016, 239, 374-383
4.940Citations (PDF)
64ORMDL proteins regulate ceramide levels during sterile inflammation
Journal of Lipid Research, 2016, 57, 1412-1422
3.643Citations (PDF)
65Modified breast cancer model for preclinical immunotherapy studies
Journal of Surgical Research, 2016, 204, 467-474
1.624Citations (PDF)
66Sphingosine-1-phosphate and estrogen signaling in breast cancer2.041Citations (PDF)
67Filamin A Expression Negatively Regulates Sphingosine-1-Phosphate-Induced NF-κB Activation in Melanoma Cells by Inhibition of Akt Signaling2.525Citations (PDF)
68Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets3.457Citations (PDF)
69Sphingosine‐1‐phosphate inhibits IL‐1‐induced expression of C‐C motif ligand 5 via c‐Fos‐dependent suppression of IFN‐β amplification loop
FASEB Journal, 2015, 29, 4853-4865
0.621Citations (PDF)
70Uncleaved ApoM Signal Peptide Is Required for Formation of Large ApoM/Sphingosine 1-Phosphate (S1P)-enriched HDL Particles
Journal of Biological Chemistry, 2015, 290, 7861-7870
2.236Citations (PDF)
71Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy
Experimental Cell Research, 2015, 333, 195-200
3.1270Citations (PDF)
72The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses6.166Citations (PDF)
73Differential regulation of autophagy and cell viability by ceramide species
Cancer Biology and Therapy, 2015, 16, 733-742
4.122Citations (PDF)
74Aberrant ORM (yeast)–like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice6.1109Citations (PDF)
75Spinster 2, a sphingosine‐1‐phosphate transporter, plays a critical role in inflammatory and autoimmune diseases
FASEB Journal, 2015, 29, 5018-5028
0.676Citations (PDF)
76PDE5 Inhibitors Enhance Celecoxib Killing in Multiple Tumor Types
Journal of Cellular Physiology, 2015, 230, 1115-1127
4.148Citations (PDF)
77Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression
Hepatology, 2015, 61, 1216-1226
10.1201Citations (PDF)
78Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy2.053Citations (PDF)
79An improved syngeneic orthotopic murine model of human breast cancer progression2.349Citations (PDF)
80A real-time high-throughput fluorescence assay for sphingosine kinases
Journal of Lipid Research, 2014, 55, 1525-1530
3.623Citations (PDF)
81Lysophospholipid receptor nomenclature review: IUPHAR Review 8
British Journal of Pharmacology, 2014, 171, 3575-3594
6.3317Citations (PDF)
82K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5
Nature Immunology, 2014, 15, 231-238
23.5130Citations (PDF)
83Sphingosine-1-phosphate in chronic intestinal inflammation and cancer2.081Citations (PDF)
84Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
Nature Neuroscience, 2014, 17, 971-980
17.1203Citations (PDF)
85Role of sphingosine kinase 1 and sphingosine‐1‐phosphate in CD40 signaling and IgE class switching
FASEB Journal, 2014, 28, 4347-4358
0.611Citations (PDF)
86Hepatic Apolipoprotein M (ApoM) Overexpression Stimulates Formation of Larger ApoM/Sphingosine 1-Phosphate-enriched Plasma High Density Lipoprotein
Journal of Biological Chemistry, 2014, 289, 2801-2814
2.278Citations (PDF)
87Sphingolipid metabolites in inflammatory disease
Nature, 2014, 510, 58-67
37.91,283Citations (PDF)
88Export of sphingosine-1-phosphate and cancer progression
Journal of Lipid Research, 2014, 55, 1839-1846
3.6153Citations (PDF)
89Memo Has a Novel Role in S1P Signaling and Crucial for Vascular Development
PLoS ONE, 2014, 9, e94114
2.316Citations (PDF)
90Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond79.7432Citations (PDF)
91Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden
Surgery, 2013, 153, 771-778
1.8108Citations (PDF)
92Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer
Cancer Cell, 2013, 23, 107-120
33.0552Citations (PDF)
93A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma6.1144Citations (PDF)
94Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
FASEB Journal, 2013, 27, 1001-1011
0.6153Citations (PDF)
95The potential of histone deacetylase inhibitors in Niemann - Pick type C disease
FEBS Journal, 2013, 280, 6367-6372
5.419Citations (PDF)
96Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate
PLoS ONE, 2013, 8, e53927
2.322Citations (PDF)
97Biological Characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a Selective Sphingosine Kinase-2 Inhibitor and Anticancer Agent
PLoS ONE, 2013, 8, e56471
2.372Citations (PDF)
98Copper Dependence of Angioproliferation in Pulmonary Arterial Hypertension in Rats and Humans3.855Citations (PDF)
99Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling
Cancer Biology and Therapy, 2012, 13, 793-803
4.127Citations (PDF)
100Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Cancer Research, 2012, 72, 726-735
3.8294Citations (PDF)
101Innate immune agonist, dsRNA, induces apoptosis in ovarian cancer cells and enhances the potency of cytotoxic chemotherapeutics
FASEB Journal, 2012, 26, 3188-3198
0.641Citations (PDF)
102Sphingosine-1-phosphate signaling and its role in disease
Trends in Cell Biology, 2012, 22, 50-60
12.0982Citations (PDF)
103Conjugated Bile Acids Activate the Sphingosine–1–Phosphate Receptor 2 in Primary Rodent Hepatocytes
Hepatology, 2012, 55, 267-276
10.1301Citations (PDF)
104The outs and the ins of sphingosine-1-phosphate in immunity
Nature Reviews Immunology, 2011, 11, 403-415
53.8788Citations (PDF)
105Development of small-molecule inhibitors of sphingosine-1-phosphate signaling
2011, 132, 352-360
60Citations (PDF)
106A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection
Basic Research in Cardiology, 2011, 106, 1341-1353
7.076Citations (PDF)
107Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
FASEB Journal, 2011, 25, 600-612
0.6359Citations (PDF)
108A Serotype 5/3 Adenovirus Expressing MDA-7/IL-24 Infects Renal Carcinoma Cells and Promotes Toxicity of Agents That Increase Ros and Ceramide Levels
Molecular Pharmacology, 2011, 79, 368-380
2.630Citations (PDF)
109Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage
Journal of Biological Chemistry, 2011, 286, 44380-44390
2.284Citations (PDF)
110Ceramide plays a prominent role in MDA‐7/IL‐24‐induced cancer‐specific apoptosis
Journal of Cellular Physiology, 2010, 222, 546-555
4.159Citations (PDF)
111Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1‐dependent upregulation of sphingosine kinase 1 transcription
FEBS Letters, 2010, 584, 4077-4082
2.727Citations (PDF)
112Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Nature, 2010, 465, 1084-1088
37.9721Citations (PDF)
113Vorinostat and Sorafenib Increase CD95 Activation in Gastrointestinal Tumor Cells through a Ca2+- De novo Ceramide-PP2A-Reactive Oxygen Species–Dependent Signaling Pathway
Cancer Research, 2010, 70, 6313-6324
3.8101Citations (PDF)
114International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature
Pharmacological Reviews, 2010, 62, 579-587
15.7328Citations (PDF)
115Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2
Journal of Biological Chemistry, 2010, 285, 10477-10486
2.2241Citations (PDF)
116PERK–Dependent Regulation of Ceramide Synthase 6 and Thioredoxin Play a Key Role in mda -7/IL-24–Induced Killing of Primary Human Glioblastoma Multiforme Cells
Cancer Research, 2010, 70, 1120-1129
3.8103Citations (PDF)
117Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells
Journal of Biological Chemistry, 2009, 284, 3408-3417
2.286Citations (PDF)
118Sphingosine‐1‐phosphate induces development of functionally mature chymase‐expressing human mast cells from hematopoietic progenitors
FASEB Journal, 2009, 23, 3506-3515
0.624Citations (PDF)
119MDA-7/IL-24–induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK–dependent mechanism
Molecular Cancer Therapeutics, 2009, 8, 1280-1291
1.946Citations (PDF)
120Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma
Immunology and Cell Biology, 2009, 87, 601-605
2.69Citations (PDF)
121Sphingosine‐1‐phosphate receptors mediate neuromodulatory functions in the CNS
Journal of Neurochemistry, 2009, 110, 1191-1202
3.852Citations (PDF)
122Export and functions of sphingosine-1-phosphate2.4156Citations (PDF)
123Involvement of sphingosine kinase in plant cell signalling
Plant Journal, 2008, 56, 64-72
6.1121Citations (PDF)
124Regulation and functions of sphingosine kinases in the brain2.4102Citations (PDF)
125Thematic Review Series: Sphingolipids. Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling*
Journal of Lipid Research, 2008, 49, 1388-1394
3.681Citations (PDF)
126Role of Sphingosine-1-Phosphate Phosphohydrolase 1 in the Regulation of Resistance Artery Tone
Circulation Research, 2008, 103, 315-324
13.170Citations (PDF)
127EGF regulates plasminogen activator inhibitor‐1 (PAI‐1) by a pathway involving c‐Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells
FASEB Journal, 2008, 22, 455-465
0.687Citations (PDF)
128Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal
FASEB Journal, 2008, 22, 2629-2638
0.6342Citations (PDF)
129OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells
Molecular Pharmacology, 2008, 73, 1168-1184
2.674Citations (PDF)
130Filamin A Links Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 1 at Lamellipodia To Orchestrate Cell Migration
Molecular and Cellular Biology, 2008, 28, 5687-5697
2.589Citations (PDF)
131Sphingosine Kinases and Sphingosine-1-Phosphate Are Critical for Transforming Growth Factor β-Induced Extracellular Signal-Regulated Kinase 1 and 2 Activation and Promotion of Migration and Invasion of Esophageal Cancer Cells
Molecular and Cellular Biology, 2008, 28, 4142-4151
2.579Citations (PDF)
132Sphingosine-1-Phosphate and Interleukin-1 Independently Regulate Plasminogen Activator Inhibitor-1 and Urokinase-Type Plasminogen Activator Receptor Expression in Glioblastoma Cells: Implications for Invasiveness
Molecular Cancer Research, 2008, 6, 1469-1477
3.152Citations (PDF)
133Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
Cancer Biology and Therapy, 2008, 7, 1648-1662
4.1163Citations (PDF)
134Sphingosine-1-phosphate synthesis and functions in mast cells
Future Lipidology, 2008, 3, 665-674
0.820Citations (PDF)
135“Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets
Pharmacological Reviews, 2008, 60, 181-195
15.7669Citations (PDF)
136Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions
Blood, 2008, 111, 4193-4200
4.8126Citations (PDF)
137A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Blood, 2008, 112, 1382-1391
4.8244Citations (PDF)
138The Role of Sphingosine-1-Phosphate and its Receptors in Asthma1.651Citations (PDF)
139Targeting sphingosine‐1‐phosphate receptors regulates in vitro and in vivo mast cell functions
FASEB Journal, 2008, 22, 484-484
0.60Citations (PDF)
140The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte Progenitors3.3179Citations (PDF)
141Sphingosine‐1‐phosphate and the immunosuppressant, FTY720‐phosphate, regulate detrusor muscle tone
FASEB Journal, 2007, 21, 2818-2828
0.621Citations (PDF)
142A Rapid and Sensitive Method to Measure Secretion of Sphingosine‐1‐Phosphate
Methods in Enzymology, 2007, , 257-264
2.115Citations (PDF)
143Functions of the Multifaceted Family of Sphingosine Kinases and Some Close Relatives
Journal of Biological Chemistry, 2007, 282, 2125-2129
2.2212Citations (PDF)
144Recycling of Sphingosine Is Regulated by the Concerted Actions of Sphingosine-1-phosphate Phosphohydrolase 1 and Sphingosine Kinase 2
Journal of Biological Chemistry, 2007, 282, 34372-34380
2.2109Citations (PDF)
145Sphingosine Kinase Type 2 Activation by ERK-mediated Phosphorylation
Journal of Biological Chemistry, 2007, 282, 12058-12065
2.2148Citations (PDF)
146The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
Blood, 2007, 109, 1077-1085
4.8147Citations (PDF)
147Autocrine and paracrine roles of sphingosine-1-phosphate8.5285Citations (PDF)
148Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells
FEBS Letters, 2007, 581, 735-740
2.7119Citations (PDF)
149Measurement of Mammalian Sphingosine‐1‐Phosphate Phosphohydrolase Activity In Vitro and In Vivo
Methods in Enzymology, 2007, , 243-256
2.113Citations (PDF)
150Regulation of fibroblast functions by lysophospholipid mediators: Potential roles in wound healing2.1110Citations (PDF)
151Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis
2007, 115, 390-399
88Citations (PDF)
152The Role of ABC Transporters in Sphingosine‐1‐Phosphate Secretion
FASEB Journal, 2007, 21,
0.61Citations (PDF)
153Sphingosine‐1‐Phosphate Induces Contraction of Floating and Stressed Fibroblast‐Populated Collagen Matrices
FASEB Journal, 2007, 21,
0.60Citations (PDF)
154Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases2.2449Citations (PDF)
155Sphingosine kinase functionally links elevated transmural pressure and increased reactive oxygen species formation in resistance arteries
FASEB Journal, 2006, 20, 702-704
0.656Citations (PDF)
156Sphingosine-1-Phosphate Phosphohydrolase Regulates Endoplasmic Reticulum-to-Golgi Trafficking of Ceramide
Molecular and Cellular Biology, 2006, 26, 5055-5069
2.551Citations (PDF)
157Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors
FASEB Journal, 2006, 20, 1924-1926
0.6135Citations (PDF)
158Role of ABCC1 in export of sphingosine-1-phosphate from mast cells7.5403Citations (PDF)
159Sphingosine and Its Analog, the Immunosuppressant 2-Amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, Interact with the CB1 Cannabinoid Receptor
Molecular Pharmacology, 2006, 70, 41-50
2.672Citations (PDF)
160A Novel Function of the Immunosuppressant Drug FTY720 Independent of Its Phosphorylation as a Direct Cytosolic Phospholipase A2 Inhibitor
FASEB Journal, 2006, 20,
0.61Citations (PDF)
161Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors
Blood, 2005, 105, 4736-4742
4.860Citations (PDF)
162Novel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitors
Journal of Neurochemistry, 2005, 95, 1298-1310
3.863Citations (PDF)
163Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression
Oncogene, 2005, 24, 178-187
6.5134Citations (PDF)
164The role of sphingosine-1-phosphate in smooth muscle contraction
Cellular Signalling, 2005, 17, 289-298
3.5120Citations (PDF)
165Sphingosine kinases, sphingosine-1-phosphate and sphingolipidomics2.244Citations (PDF)
166Targeted lipidomics: Signaling lipids and drugs of abuse2.210Citations (PDF)
167Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes
Hepatology, 2005, 42, 1291-1299
10.1122Citations (PDF)
168Role of Sphingosine Kinase 2 in Cell Migration toward Epidermal Growth Factor
Journal of Biological Chemistry, 2005, 280, 29462-29469
2.2143Citations (PDF)
169SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism
Journal of Biological Chemistry, 2005, 280, 37118-37129
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170Essential Role for Sphingosine Kinases in Neural and Vascular Development
Molecular and Cellular Biology, 2005, 25, 11113-11121
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171Ceramide 1-Phosphate, a Mediator of Phagocytosis
Journal of Biological Chemistry, 2005, 280, 26612-26621
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172Arabidopsis Sphingosine Kinase and the Effects of Phytosphingosine-1-Phosphate on Stomatal Aperture
Plant Physiology, 2005, 137, 724-737
5.5154Citations (PDF)
173A novel acylglycerol kinase that produces lysophosphatidic acid modulates cross talk with EGFR in prostate cancer cells
Journal of Cell Biology, 2005, 169, 801-811
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174The S1P2 Receptor Negatively Regulates Platelet-Derived Growth Factor-Induced Motility and Proliferation
Molecular and Cellular Biology, 2005, 25, 4237-4249
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175Epithelial transport and barrier function in occludin-deficient mice2.2294Citations (PDF)
176Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells
FEBS Letters, 2005, 579, 5313-5317
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177Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720
Journal of Biological Chemistry, 2004, 279, 52487-52492
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178Role of Sphingosine-1-phosphate Phosphatase 1 in Epidermal Growth Factor-induced Chemotaxis
Journal of Biological Chemistry, 2004, 279, 34290-34297
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179Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension
Journal of Cell Biology, 2004, 166, 381-392
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180Transactivation of Sphingosine-1–Phosphate Receptors by FcεRI Triggering Is Required for Normal Mast Cell Degranulation and Chemotaxis9.3321Citations (PDF)
181Deoxycholic Acid Activates the c-Jun N-terminal Kinase Pathway via FAS Receptor Activation in Primary Hepatocytes
Journal of Biological Chemistry, 2004, 279, 5821-5828
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182Generation and metabolism of bioactive sphingosine-1-phosphate3.0200Citations (PDF)
183Aminoacylase 1 is a sphingosine kinase 1-interacting protein
FEBS Letters, 2004, 568, 30-34
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184Modulation of adpative immune responses by sphingosine-1-phosphate5.319Citations (PDF)
185Glycosphingolipids and cell death
Glycoconjugate Journal, 2003, 20, 39-47
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186Sphingosine 1-phosphate signal survival and mitogenesis are mediated by lipid-stereospecific binding of triacylglycerol-rich lipoproteins5.57Citations (PDF)
187Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation
Cell Calcium, 2003, 33, 119-128
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188A specific ceramide kinase assay to measure cellular levels of ceramide
Analytical Biochemistry, 2003, 320, 259-265
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189Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins
Nature, 2003, 423, 651-654
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190Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells13.330Citations (PDF)
191Sphingosine-1-phosphate: an enigmatic signalling lipid78.12,065Citations (PDF)
192The G Protein-Coupled Receptor GPR4 Suppresses ERK Activation in a Ligand-Independent Manner†
Biochemistry, 2003, 42, 12181-12191
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193The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2
FEBS Letters, 2003, 554, 189-193
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194Pleiotropic actions of sphingosine-1-phosphate
Progress in Lipid Research, 2003, 42, 344-357
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195Preferential Signaling and Induction of Allergy-promoting Lymphokines Upon Weak Stimulation of the High Affinity IgE Receptor on Mast Cells
Journal of Experimental Medicine, 2003, 197, 1453-1465
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196Sphingosine‐1‐phosphate stimulates contraction of human airway smooth muscle cells
FASEB Journal, 2003, 17, 1789-1799
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197Sphingosine Kinase Modulates Microvascular Tone and Myogenic Responses Through Activation of RhoA/Rho Kinase
Circulation, 2003, 108, 342-347
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198Sphingosine Kinase Type 2 Is a Putative BH3-only Protein That Induces Apoptosis
Journal of Biological Chemistry, 2003, 278, 40330-40336
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199Sphingosine Kinase Type 1 Induces G12/13-mediated Stress Fiber Formation, yet Promotes Growth and Survival Independent of G Protein-coupled Receptors
Journal of Biological Chemistry, 2003, 278, 46452-46460
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200Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release
Journal of Biological Chemistry, 2003, 278, 38206-38213
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201Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity
Journal of Biological Chemistry, 2002, 277, 32947-32953
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202Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis
Journal of Cell Biology, 2002, 158, 1039-1049
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203Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase
Journal of Biological Chemistry, 2002, 277, 10539-10546
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204Involvement of Sphingosine Kinase in TNF-α-stimulated Tetrahydrobiopterin Biosynthesis in C6 Glioma Cells
Journal of Biological Chemistry, 2002, 277, 12649-12656
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205Ceramide Kinase, a Novel Lipid Kinase
Journal of Biological Chemistry, 2002, 277, 23294-23300
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206Sphingosine kinases: A novel family of lipid kinases4.3149Citations (PDF)
207Characterization of Murine Sphingosine-1-phosphate Phosphohydrolase
Journal of Biological Chemistry, 2002, 277, 8920-8927
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208Sphingosine 1-Phosphate, a Key Cell Signaling Molecule
Journal of Biological Chemistry, 2002, 277, 25851-25854
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209Sphingosine Kinase Type 1 Promotes Estrogen-Dependent Tumorigenesis of Breast Cancer MCF-7 Cells
Experimental Cell Research, 2002, 281, 115-127
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210Sphingosine-1-phosphate: dual messenger functions
FEBS Letters, 2002, 531, 54-57
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211Sphingosine-1-phosphate and lipid phosphohydrolases2.4106Citations (PDF)
212Lipid mediators of angiogenesis and the signalling pathways they initiate2.471Citations (PDF)
213Sphingosine kinase, sphingosine-1-phosphate, and apoptosis2.4512Citations (PDF)
214The roles of sphingosine-1-phosphate in asthma
Molecular Immunology, 2002, 38, 1239-1245
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215Sphingosine 1-phosphate signaling: providing cells with a sense of direction
Trends in Cell Biology, 2002, 12, 236-242
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216Ceramide-induced cell death in primary neuronal cultures: Upregulation of ceramide levels during neuronal apoptosis3.170Citations (PDF)
217Title is missing!
Neurochemical Research, 2002, 27, 619-627
3.476Citations (PDF)
218Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor
FEBS Letters, 2001, 503, 85-90
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219Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate
FEBS Letters, 2001, 509, 239-244
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220Sphingosine-1-phosphate: an emerging therapeutic target0.84Citations (PDF)
221Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells
Journal of Neurochemistry, 2001, 76, 1573-1584
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222Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells13.3130Citations (PDF)
223Sphingosine kinase: a mediator of vital cellular functions2.2153Citations (PDF)
224EDG‐1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration
FASEB Journal, 2001, 15, 2649-2659
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225Nrg-1 Belongs to the Endothelial Differentiation Gene Family of G Protein-coupled Sphingosine-1-phosphate Receptors
Journal of Biological Chemistry, 2001, 276, 5692-5699
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226Dynamic modeling of EDG1 receptor structural changes induced by site-directed mutations1.214Citations (PDF)
227Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6
Blood, 2000, 95, 2624-2629
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228Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation10.61,081Citations (PDF)
229Role of Ceramide in Neuronal Cell Death and Differentiation
Journal of Neurotrauma, 2000, 17, 891-898
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230Divergence in Regulation of Nitric-oxide Synthase and Its Cofactor Tetrahydrobiopterin by Tumor Necrosis Factor-α
Journal of Biological Chemistry, 2000, 275, 13275-13281
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231Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate
Journal of Biological Chemistry, 2000, 275, 39379-39384
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232Involvement of Sphingosine in Mitochondria-dependent Fas-induced Apoptosis of Type II Jurkat T Cells
Journal of Biological Chemistry, 2000, 275, 15691-15700
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233Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death7.5196Citations (PDF)
234Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform
Journal of Biological Chemistry, 2000, 275, 19513-19520
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235Sphingosine-1-Phosphate Activates Phospholipase D in Human Airway Epithelial Cells via a G Protein-Coupled Receptor2.820Citations (PDF)
236Functions of a new family of sphingosine-1-phosphate receptors2.4185Citations (PDF)
237Functional characterization of human sphingosine kinase-1
FEBS Letters, 2000, 473, 81-84
2.7103Citations (PDF)
238Sphingosine-1-phosphate: signaling inside and out
FEBS Letters, 2000, 476, 55-57
2.7261Citations (PDF)
239Sphingosine 1‐Phosphate: A Ligand for the EDG‐1 Family of G‐Protein‐Coupled Receptors4.059Citations (PDF)
240Structural Features of EDG1 Receptor‐Ligand Complexes Revealed by Computational Modeling and Mutagenesis4.024Citations (PDF)
241Platelet‐derived growth factor‐induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCγ
FASEB Journal, 1999, 13, 1593-1600
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242MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts7.543Citations (PDF)
243Sphingosine 1-Phosphate-induced Cell Rounding and Neurite Retraction Are Mediated by the G Protein-coupled Receptor H218
Journal of Biological Chemistry, 1999, 274, 4626-4632
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244Ligand-induced Trafficking of the Sphingosine-1-phosphate Receptor EDG-1
Molecular Biology of the Cell, 1999, 10, 1179-1190
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245Sphingosine 1-Phosphate Stimulates Cell Migration through a Gi-coupled Cell Surface Receptor
Journal of Biological Chemistry, 1999, 274, 35343-35350
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246Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase2.048Citations (PDF)
247Enzymatic Measurement of Sphingosine 1-Phosphate
Analytical Biochemistry, 1999, 272, 80-86
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248Differential effects of free and liposome-associated 1-O-octadecyl-2-O-methylglycerophosphocholine on protein kinase C
FEBS Letters, 1999, 454, 137-141
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249Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival
Journal of Cell Biology, 1999, 147, 545-558
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250Involvement of Focal Adhesion Kinase in Inhibition of Motility of Human Breast Cancer Cells by Sphingosine 1-Phosphate
Experimental Cell Research, 1999, 247, 17-28
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251Sphingosine 1-phosphate: a prototype of a new class of second messengers
Journal of Leukocyte Biology, 1999, 65, 341-344
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252Title is missing!2.625Citations (PDF)
253Glycosphingolipid composition of MDA-MB-231 and MCF-7 human breast cancer cell lines2.386Citations (PDF)
254Sphingosine‐1‐Phosphate in Cell Growth and Cell Death a4.0212Citations (PDF)
255Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate—caged SPP2.044Citations (PDF)
256The potent lipid mitogen sphingosylphosphocholine activates the DNA binding activity of upstream stimulating factor (USF), a basic helix-loop-helix-zipper protein
Lipids and Lipid Metabolism, 1998, 1390, 225-236
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257N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C:  Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide†
Biochemistry, 1998, 37, 12892-12898
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258Purification and Characterization of Rat Kidney Sphingosine Kinase
Journal of Biological Chemistry, 1998, 273, 12576-12583
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259Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival
Journal of Cell Biology, 1998, 142, 229-240
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260Sphingosine-1-Phosphate: A Lipid Second Messenger Regulating Cell Growth and Survival3.610Citations (PDF)
261Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase
Journal of Biological Chemistry, 1998, 273, 23722-23728
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262A GTPase-independent Mechanism of p21-activated Kinase Activation
Journal of Biological Chemistry, 1998, 273, 8137-8144
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263Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes
Journal of Biological Chemistry, 1998, 273, 2910-2916
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264Sphingoid base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and stress response7.5250Citations (PDF)
265Sphingosine 1-Phosphate Stimulates Tyrosine Phosphorylation of Crk
Journal of Biological Chemistry, 1997, 272, 16211-16215
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266Divergence in Signal Transduction Pathways of Platelet-derived Growth Factor (PDGF) and Epidermal Growth Factor (EGF) Receptors
Journal of Biological Chemistry, 1997, 272, 10777-10783
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267Sphingosine 1-phosphate stimulates Rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts
Biochemical Journal, 1997, 324, 481-488
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268Calcium influx inhibits MT1-MMP processing and blocks MMP-2 activation
FEBS Letters, 1997, 412, 568-572
2.734Citations (PDF)
269Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors
FEBS Letters, 1997, 417, 173-176
2.796Citations (PDF)
270Differential effects of sphingomyelinase and cell-permeable ceramide analogs on proliferation of Swiss 3T3 fibroblasts
Lipids and Lipid Metabolism, 1997, 1348, 311-323
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271KSR stimulates Raf-1 activity in a kinase-independent manner7.5166Citations (PDF)
272Sphingolipids—The Enigmatic Lipid Class: Biochemistry, Physiology, and Pathophysiology3.2627Citations (PDF)
273Fidelity of Translesional Synthesis past Benzo[a]pyrene Diol Epoxide−2‘-Deoxyguanosine DNA Adducts:  Marked Effects of Host Cell, Sequence Context, and Chirality†
Biochemistry, 1996, 35, 16646-16651
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274Signal transduction through lipid second messengers3.9505Citations (PDF)
275Effect of acidic phospholipids on sphingosine kinase3.093Citations (PDF)
276Sphingoid bases and phospholipase D activation2.625Citations (PDF)
277Synthesis of erythro-ω-aminosphingosine and preparation of an affinity column for sphingosine kinase purification
Tetrahedron Letters, 1996, 37, 3279-3282
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278Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1
Glycoconjugate Journal, 1996, 13, 937-945
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279Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
Nature, 1996, 381, 800-803
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280A New Wound Healing Agent—Sphingosylphosphorylcholine2.364Citations (PDF)
281Sphingosylphosphocholine, a signaling molecule which accumulates in Niemann-Pick disease type A, stimulates DNA-binding activity of the transcription activator protein AP-1.7.546Citations (PDF)
282Sphingolipid metabolites: Members of a new class of lipid second messengers2.5214Citations (PDF)
283Sphingosine 1-Phosphate Rapidly Activates the Mitogen-activated Protein Kinase Pathway by a G Protein-dependent Mechanism
Journal of Biological Chemistry, 1995, 270, 11484-11488
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284Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate
Journal of Biological Chemistry, 1995, 270, 10272-10277
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285The role of calcium influx in cellular proliferation induced by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin
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286Sphingosine-1-phosphate, a novel second messenger involved in cell growth regulation and signal transduction, affects growth and invasiveness of human breast cancer cells2.345Citations (PDF)
287Sphingosine Kinase from Swiss 3T3 Fibroblasts: A Convenient Assay for the Measurement of Intracellular Levels of Free Sphingoid Bases
Analytical Biochemistry, 1994, 223, 306-312
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288Glycosphingolipids of Rat T Cells. Predominance of Asialo-GM1 and GD1c
Biochemistry, 1994, 33, 4661-4666
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289Stereospecificity of sphingosine-induced intracellular calcium mobilization and cellular proliferation.
Journal of Biological Chemistry, 1994, 269, 17924-17930
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290Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts.
Journal of Biological Chemistry, 1994, 269, 16512-16517
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291Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.
Journal of Biological Chemistry, 1994, 269, 3181-3188
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292Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
Nature, 1993, 365, 557-560
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293Glycopinion
Glycoconjugate Journal, 1992, 9, 109-117
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294Sphingomyelinase and cell-permeable ceramide analogs stimulate cellular proliferation in quiescent Swiss 3T3 fibroblasts.
Journal of Biological Chemistry, 1992, 267, 26121-26127
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295Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation
Journal of Biological Chemistry, 1992, 267, 23122-23128
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296Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines2.1114Citations (PDF)
297Cautionary note on the use of the B subunit of cholera toxin as a ganglioside GM1 probe: Detection of cholera toxin A subunit in B subunit preparations by a sensitive adenylate cyclase assay3.019Citations (PDF)
298The Bimodal growth response of swiss 3T3 cells to the B subunit of cholera toxin is independent of the density of its receptor, ganglioside GM1
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299Increases in phosphatidic acid levels accompany sphingosine-stimulated proliferation of quiescent Swiss 3T3 cells.
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300Sphingosine stimulates cellular proliferation via a protein kinase C-independent pathway.2.2220Citations (PDF)
301Interaction of the B subunit of cholera toxin with endogenous ganglioside GM1 causes changes in membrane potential of rat thymocytes
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302Possible Involvement of a GTP-binding Protein in a Late Event During Endogenous Ganglioside-modulated Cellular Proliferation
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303Inhibition of protein kinase C-dependent cellular proliferation by interaction of endogenous ganglioside GM1 with the B subunit of cholera toxin
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304Asymmetric distribution of gangliosides in rat renal brush-border and basolateral membranes2.231Citations (PDF)
305Mitogenesis of 3T3 fibroblasts induced by endogenous ganglioside is not mediated by cAMP, protein kinase C, or phosphoinositides turnover
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306Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin3.623Citations (PDF)
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308Gangliosides modulate sodium transport in cultured toad kidney epithelia.
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309Fluorescent derivatives of ganglioside GM1 function as receptors for cholera toxin
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312Fluorescence labeling of cell surface glycoconjugates with lucifer yellow CH2.123Citations (PDF)
313A novel approach for the topographical localization of glycolipids on the cell surface2.224Citations (PDF)
314Fluorescent reagents for the labeling of glycoconjugates in solution and on cell surfaces2.148Citations (PDF)
315Involvement of gangliosides in lymphocyte stimulation.7.540Citations (PDF)
316Control of Leaf Senescence by Growth Retardants
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317TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition
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318Sphingosine kinase 21.00Citations (PDF)
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