82(top 5%)
PR articles
14.8K(top 1%)
PR citations
43(top 1%)
PR h-index
44(top 1%)
h-index
101
documents
19.3K
doc citations
2.2K
citing journals
100
times ranked

Publications

90 peer-reviewed articles • 17,261 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
Sort: Year | Citations
#ArticleIFCitationsLinks
1Complex rearrangements fuel ER+ and HER2+ breast tumours
Nature, 2025, 638, 510-518
31.333Citations (PDF)
2Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
Clinical Cancer Research, 2024, 30, 849-864
4.540Citations (PDF)
3Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity
Science, 2024, 384,
26.526Citations (PDF)
4Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers
Science, 2024, 385,
26.558Citations (PDF)
5The G 1 -S transition is promoted by Rb degradation via the E3 ligase UBR5
Science Advances, 2024, 10,
8.219Citations (PDF)
6Cancers adapt to their mutational load by buffering protein misfolding stress
ELife, 2023, 12,
1.07Citations (PDF)
7Deterministic evolution and stringent selection during preneoplasia
Nature, 2023, 618, 383-393
31.381Citations (PDF)
8PhyloVelo enhances transcriptomic velocity field mapping using monotonically expressed genes
Nature Biotechnology, 2023, 42, 778-789
20.271Citations (PDF)
9Serine starvation silences estrogen receptor signaling through histone hypoacetylation
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120,
5.320Citations (PDF)
10Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
Molecular Cancer Research, 2022, 18, 599-611
2.679Citations (PDF)
11Patient perspectives on window of opportunity clinical trials in early-stage breast cancer
Breast Cancer Research and Treatment, 2022, 194, 171-178
1.82Citations (PDF)
12The Mettl3 epitranscriptomic writer amplifies p53 stress responses
Molecular Cell, 2022, 82, 2370-2384.e10
8.771Citations (PDF)
13Single-cell analyses define a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer
Nature Genetics, 2022, 54, 985-995
14.1301Citations (PDF)
14Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer
Nature Communications, 2022, 13,
11.065Citations (PDF)
15Molecular Heterogeneity and Evolution in Breast Cancer
Annual Review of Cancer Biology, 2021, 5, 79-94
2.730Citations (PDF)
16A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer
Cancers, 2021, 13, 316
2.719Citations (PDF)
17The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer
Nature Communications, 2021, 12,
11.042Citations (PDF)
18An expanded universe of cancer targets
Cell, 2021, 184, 1142-1155
23.8212Citations (PDF)
19Cell of Origin Influences Pancreatic Cancer Subtype
Cancer Discovery, 2021, 11, 660-677
6.8116Citations (PDF)
20The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D
Nature, 2021, 592, 794-798
31.3170Citations (PDF)
21Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response
Nature Cancer, 2021, 2, 400-413
15.087Citations (PDF)
22Transcriptome and genome evolution during HER2-amplified breast neoplasia
Breast Cancer Research, 2021, 23,
3.45Citations (PDF)
23Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis
Nature, 2021, 597, 549-554
31.3182Citations (PDF)
24A CRISPR/Cas9-Engineered ARID1A -Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation
Cancer Discovery, 2021, 11, 1562-1581
6.8162Citations (PDF)
25Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07)
Nature Communications, 2020, 11,
11.056Citations (PDF)
26Characterizing the ecological and evolutionary dynamics of cancer
Nature Genetics, 2020, 52, 759-767
14.1149Citations (PDF)
27The m 6 A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117, 21441-21449
5.3107Citations (PDF)
28Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program
Molecular Cell, 2020, 80, 452-469.e9
8.7107Citations (PDF)
29Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases
Nature Genetics, 2020, 52, 701-708
14.1352Citations (PDF)
30CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities
Nature, 2020, 580, 136-141
31.3313Citations (PDF)
31The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
Cell, 2020, 181, 236-249
23.8576Citations (PDF)
32Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
Annals of Oncology, 2020, 31, 745-759
8.11,364Citations (PDF)
33Clonal replacement of tumor-specific T cells following PD-1 blockade
Nature Medicine, 2019, 25, 1251-1259
22.81,507Citations (PDF)
34Quantitative evidence for early metastatic seeding in colorectal cancer
Nature Genetics, 2019, 51, 1113-1122
14.1461Citations (PDF)
35Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups
Nature, 2019, 567, 399-404
31.3384Citations (PDF)
36Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Nature Communications, 2019, 10,
11.053Citations (PDF)
37Chromatin regulators mediate anthracycline sensitivity in breast cancer
Nature Medicine, 2019, 25, 1721-1727
22.839Citations (PDF)
38Assessment ofERBB2/HER2Status inHER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines
JAMA Oncology, 2019, 5, 366
11.036Citations (PDF)
39Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
Cell, 2018, 173, 1398-1412.e22
23.8470Citations (PDF)
40Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
Nature Genetics, 2018, 50, 483-486
14.1141Citations (PDF)
41Big Bang Tumor Growth and Clonal Evolution
Cold Spring Harbor Perspectives in Medicine, 2018, 8, a028381
2.952Citations (PDF)
42Identification of copy number variations and translocations in cancer cells from Hi-C data
Bioinformatics, 2018, 34, 338-345
3.295Citations (PDF)
43Detecting presence of mutational signatures in cancer with confidence
Bioinformatics, 2018, 34, 330-337
3.2103Citations (PDF)
44Tumor Molecular Profiling Aids in Determining Tissue of Origin and Therapy for Metastatic Adenocarcinoma in a Patient With Multiple Primary Malignancies
JCO Precision Oncology, 2018, , 1-4
1.11Citations (PDF)
45The chromatin accessibility landscape of primary human cancers
Science, 2018, 362,
26.51,175Citations (PDF)
46Quantification of subclonal selection in cancer from bulk sequencing data
Nature Genetics, 2018, 50, 895-903
14.1282Citations (PDF)
47Harnessing Tumor Evolution to Circumvent Resistance
Trends in Genetics, 2018, 34, 639-651
7.666Citations (PDF)
48Bayesian Network Inference Modeling Identifies TRIB1 as a Novel Regulator of Cell-Cycle Progression and Survival in Cancer Cells
Cancer Research, 2017, 77, 1575-1585
4.299Citations (PDF)
49A population genetics perspective on the determinants of intra-tumor heterogeneity
Biochimica Et Biophysica Acta: Reviews on Cancer, 2017, 1867, 109-126
5.848Citations (PDF)
50A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer
Cancer Cell, 2017, 32, 460-473.e6
28.7178Citations (PDF)
51Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
Cell Stem Cell, 2017, 21, 78-90.e6
12.0372Citations (PDF)
52Between-region genetic divergence reflects the mode and tempo of tumor evolution
Nature Genetics, 2017, 49, 1015-1024
14.1177Citations (PDF)
53Early mutation bursts in colorectal tumors
PLoS ONE, 2017, 12, e0172516
1.51Citations (PDF)
54Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer
Breast Cancer Research, 2016, 18,
3.417Citations (PDF)
55Many private mutations originate from the first few divisions of a human colorectal adenoma
Journal of Pathology, 2015, 237, 355-362
3.235Citations (PDF)
56Genomic profiling of breast cancers
Current Opinion in Obstetrics and Gynecology, 2015, 27, 34-39
1.320Citations (PDF)
57A Big Bang model of human colorectal tumor growth
Nature Genetics, 2015, 47, 209-216
14.11,026Citations (PDF)
58A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
Molecular Oncology, 2015, 9, 115-127
2.839Citations (PDF)
59Contributions to Drug Resistance in Glioblastoma Derived from Malignant Cells in the Sub-Ependymal Zone
Cancer Research, 2015, 75, 194-202
4.259Citations (PDF)
60Genome-driven integrated classification of breast cancer validated in over 7,500 samples
Genome Biology, 2014, 15,
4.8211Citations (PDF)
61COMPLEX EVOLUTIONARY DYNAMICS GENERATES GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN INDIVIDUAL PATIENTS WITH GLIOBLASTOMA
Neuro-Oncology, 2014, 16, iii7-iii7
0.91Citations (PDF)
62The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31
Molecular Cell, 2014, 53, 806-818
8.760Citations (PDF)
63Genome-driven integrated classification of breast cancer validated in over 7,500 samples
Genome Biology, 2014, 15, 431
12.14Citations (PDF)
64Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110, 4009-4014
5.31,701Citations (PDF)
65Single-Molecule Genomic Data Delineate Patient-Specific Tumor Profiles and Cancer Stem Cell Organization
Cancer Research, 2013, 73, 41-49
4.271Citations (PDF)
66The shaping and functional consequences of the microRNA landscape in breast cancer
Nature, 2013, 497, 378-382
31.3399Citations (PDF)
67Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
PLoS Computational Biology, 2013, 9, e1003047
1.983Citations (PDF)
68Precise inference of copy number alterations in tumor samples from SNP arrays
Bioinformatics, 2013, 29, 2964-2970
3.213Citations (PDF)
69Quantitative Image Analysis of Cellular Heterogeneity in Breast Tumors Complements Genomic Profiling
Science Translational Medicine, 2012, 4,
8.7396Citations (PDF)
70A Sparse Regulatory Network of Copy-Number Driven Gene Expression Reveals Putative Breast Cancer Oncogenes
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2012, 9, 947-954
2.628Citations (PDF)
71Calling Sample Mix-Ups in Cancer Population Studies
PLoS ONE, 2012, 7, e41815
1.59Citations (PDF)
72The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
Nature, 2012, 486, 346-352
31.35,806Citations (PDF)
73The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Nature, 2012, 486, 395-399
31.31,936Citations (PDF)
74ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
EMBO Molecular Medicine, 2011, 3, 167-180
4.7126Citations (PDF)
75Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancer
Bioinformatics, 2011, 27, 2679-2685
3.22Citations (PDF)
76The importance of platform annotation in interpreting microarray data
Lancet Oncology, The, 2010, 11, 717
14.516Citations (PDF)
77Swift: primary data analysis for the Illumina Solexa sequencing platform
Bioinformatics, 2009, 25, 2194-2199
3.291Citations (PDF)
78The pitfalls of platform comparison: DNA copy number array technologies assessed
BMC Genomics, 2009, 10, 588
2.182Citations (PDF)
79Product Length, Dye Choice, and Detection Chemistry in the Bead-Emulsion Amplification of Millions of Single DNA Molecules in Parallel
Analytical Chemistry, 2009, 81, 5770-5776
5.315Citations (PDF)
80Explaining differences in saturation levels for Affymetrix GeneChip® arrays
Nucleic Acids Research, 2007, 35, 4154-4163
11.237Citations (PDF)
81Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophilareveals a species-general network of aging and metabolic genes
Genome Biology, 2007, 8,
12.1124Citations (PDF)
82Title is missing!
Molecular Cancer, 2004, 3, 10
19.930Citations (PDF)
83Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing
ELife, 0, 9,
1.065Citations (PDF)
84Most cancers carry a substantial deleterious load due to Hill-Robertson interference
ELife, 0, 11,
1.029Citations (PDF)
85Title is missing!
0
1Citations (PDF)
86Cancers adapt to their mutational load by buffering protein misfolding stress
ELife, 0, 12,
1.03Citations (PDF)
87Polyclonal origins of human premalignant colorectal lesions
Nature, 0, 650, 1017-1024
31.310Citations (PDF)
88Abstract 1438: Generative AI improves breast cancer genomic subtype prediction from histology images.
Cancer Research, 0, 86, 1438-1438
4.20Citations (PDF)
89Spatial organization of immune surveillance by germline mutation status in the Breast Cancer Family Registry.
Journal of Clinical Oncology, 0, 44, 10566-10566
12.30Citations (PDF)
90Guarding epithelial integrity: origins of adaptive immunity and cancer immunosurveillance over time and space
0, 14, e015149
0Citations (PDF)