| 1 | The complex interplay between aging and cancer | 13.3 | 42 | Citations (PDF) |
| 2 | Weaponizing CRISPR/Cas9 for selective elimination of cells with an aberrant genome | 1.8 | 6 | Citations (PDF) |
| 3 | Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT) | 6.6 | 4 | Citations (PDF) |
| 4 | SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence | 12.6 | 117 | Citations (PDF) |
| 5 | Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs | 10.8 | 25 | Citations (PDF) |
| 6 | DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging | 3.5 | 38 | Citations (PDF) |
| 7 | BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1 | 10.8 | 42 | Citations (PDF) |
| 8 | Telomere dysfunction in ageing and age-related diseases | 12.6 | 708 | Citations (PDF) |
| 9 | TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance | 10.8 | 26 | Citations (PDF) |
| 10 | DNA Damage Triggers a New Phase in Neurodegeneration | 5.5 | 57 | Citations (PDF) |
| 11 | MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends | 4.4 | 65 | Citations (PDF) |
| 12 | A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres | 3.2 | 3 | Citations (PDF) |
| 13 | DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining | 1.7 | 23 | Citations (PDF) |
| 14 | Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury | 3.1 | 63 | Citations (PDF) |
| 15 | The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress | 4.4 | 33 | Citations (PDF) |
| 16 | Telomere transcription in ageing | 9.0 | 75 | Citations (PDF) |
| 17 | Cellular senescence in ageing: from mechanisms to therapeutic opportunities | 69.0 | 2,048 | Citations (PDF) |
| 18 | Detection of Telomeric DNA:RNA Hybrids Using TeloDRIP-qPCR | 3.2 | 3 | Citations (PDF) |
| 19 | Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs | 2.7 | 67 | Citations (PDF) |
| 20 | Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome | 10.8 | 129 | Citations (PDF) |
| 21 | Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors | 12.6 | 343 | Citations (PDF) |
| 22 | PREP1 tumor suppressor protects the late-replicating DNA by controlling its replication timing and symmetry | 2.7 | 21 | Citations (PDF) |
| 23 | From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond | 42.5 | 80 | Citations (PDF) |
| 24 | NOTCH1 modulates activity of DNA-PKcs | 1.2 | 4 | Citations (PDF) |
| 25 | BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment | 10.8 | 242 | Citations (PDF) |
| 26 | A novel single-cell method provides direct evidence of persistent DNA damage in senescent cells and aged mammalian tissues | 4.8 | 76 | Citations (PDF) |
| 27 | Express or repress? The transcriptional dilemma of damaged chromatin | 3.3 | 36 | Citations (PDF) |
| 28 | DNA damage response inhibition at dysfunctional telomeres by modulation of telomeric DNA damage response RNAs | 10.8 | 95 | Citations (PDF) |
| 29 | Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53 | 2.7 | 51 | Citations (PDF) |
| 30 | A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks | 10.8 | 126 | Citations (PDF) |
| 31 | Recent Advancements in DNA Damage–Transcription Crosstalk and High-Resolution Mapping of DNA Breaks | 4.1 | 43 | Citations (PDF) |
| 32 | The cohesin complex prevents Myc-induced replication stress | 6.6 | 20 | Citations (PDF) |
| 33 | Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks | 12.6 | 372 | Citations (PDF) |
| 34 | Transcription and DNA Damage: Holding Hands or Crossing Swords? | 2.9 | 61 | Citations (PDF) |
| 35 | DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors | 1.7 | 139 | Citations (PDF) |
| 36 | RNA
‐processing proteins regulate Mec1/
ATR
activation by promoting generation of
RPA
‐coated ss
DNA | 3.5 | 33 | Citations (PDF) |
| 37 | Notch is a direct negative regulator of the DNA-damage response | 5.8 | 82 | Citations (PDF) |
| 38 | Human nuclear ARGONAUTE 2 interacts in vivo only with small RNAs and not with DNA | 2.3 | 2 | Citations (PDF) |
| 39 | Telomerase abrogates aneuploidy‐induced telomere replication stress, senescence and cell depletion | 5.1 | 80 | Citations (PDF) |
| 40 | Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing | 2.4 | 146 | Citations (PDF) |
| 41 | Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication | 10.8 | 88 | Citations (PDF) |
| 42 | A direct role for small non-coding RNAs in DNA damage response | 10.9 | 124 | Citations (PDF) |
| 43 | Stable Cellular Senescence Is Associated with Persistent DDR Activation | 1.5 | 161 | Citations (PDF) |
| 44 | DNA Damage in Mammalian Neural Stem Cells Leads to Astrocytic Differentiation Mediated by BMP2 Signaling through JAK-STAT | 3.0 | 91 | Citations (PDF) |
| 45 | ImmunoFISH for Adherent Cultured Mammalian Cells | 0.2 | 3 | Citations (PDF) |
| 46 | ImmunoFISH for Mice and Baboons Frozen Sections | 0.2 | 0 | Citations (PDF) |
| 47 | Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation | 10.7 | 29 | Citations (PDF) |
| 48 | Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer | 34.5 | 209 | Citations (PDF) |
| 49 | Is cellular senescence an example of antagonistic pleiotropy? | 4.8 | 76 | Citations (PDF) |
| 50 | Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions | 5.1 | 218 | Citations (PDF) |
| 51 | Site-specific DICER and DROSHA RNA products control the DNA-damage response | 30.6 | 522 | Citations (PDF) |
| 52 | Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation | 12.6 | 768 | Citations (PDF) |
| 53 | Never-ageing cellular senescence | 2.8 | 24 | Citations (PDF) |
| 54 | Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer | 12.6 | 340 | Citations (PDF) |
| 55 | Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer? | 10.5 | 36 | Citations (PDF) |
| 56 | Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells | 1.2 | 90 | Citations (PDF) |
| 57 | Cellular senescence: hot or what? | 2.4 | 106 | Citations (PDF) |
| 58 | Living on a break: cellular senescence as a DNA-damage response | 34.5 | 1,097 | Citations (PDF) |
| 59 | Chemokine Signaling via the CXCR2 Receptor Reinforces SenescenceCell, 2008, 133, 1006-1018 | 23.4 | 1,689 | Citations (PDF) |
| 60 | Complex engagement of DNA damage response pathways in human cancer and in lung tumor progression | 2.2 | 76 | Citations (PDF) |
| 61 | Title is missing! | 3.2 | 12 | Citations (PDF) |
| 62 | Cellular senescence: when bad things happen to good cells | 69.0 | 4,124 | Citations (PDF) |
| 63 | Breaking news: high-speed race ends in arrest – how oncogenes induce senescence | 10.9 | 76 | Citations (PDF) |
| 64 | Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication | 30.6 | 1,732 | Citations (PDF) |
| 65 | Functional links between telomeres and proteins of the DNA-damage response | 2.8 | 253 | Citations (PDF) |
| 66 | A DNA damage checkpoint response in telomere-initiated senescence | 30.6 | 2,654 | Citations (PDF) |
| 67 | The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku | 3.5 | 87 | Citations (PDF) |
| 68 | Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis | 3.5 | 39 | Citations (PDF) |
| 69 | Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells | 2.5 | 269 | Citations (PDF) |
| 70 | Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha | 10.7 | 25 | Citations (PDF) |
| 71 | Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability | 14.1 | 225 | Citations (PDF) |
| 72 | Cleavage and Inactivation of ATM during Apoptosis | 1.5 | 99 | Citations (PDF) |
| 73 | Interaction of HIV-1 Tat Protein with Heparin | 1.3 | 184 | Citations (PDF) |
| 74 | A human binding site for transcription factor USF/MLTF mimics the negative regulatory element of human immunodeficiency virus type 1 | 1.6 | 94 | Citations (PDF) |
| 75 | Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae | 1.0 | 29 | Citations (PDF) |
| 76 | Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer’s disease | 5.1 | 5 | Citations (PDF) |
| 77 | Site-specific DNA double-strand break induces local transcription in cis and protein expression | 3.1 | 0 | Citations (PDF) |
