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138 peer-reviewed articles • 12,743 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Sex-biased human thymic architecture guides T cell development through spatially defined niches
Developmental Cell, 2025, 60, 152-169.e8
5.322Citations (PDF)
2Rebuilding and rebooting immunity with stem cells
Cell Stem Cell, 2024, 31, 597-616
11.610Citations (PDF)
3T-Cell Differentiation from Hematopoietic Progenitor Cells Using 3D Thymic-like Hydrogels
GEN Biotechnology, 2024, 3, 136-151
0.63Citations (PDF)
4Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells
Cell Systems, 2024, 15, 1245-1263.e10
3.512Citations (PDF)
5Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies
Stem Cell Reports, 2023, 18, 377-393
3.022Citations (PDF)
6Engineering T Cell Development for the Next Generation of Stem Cell-Derived Immunotherapies
GEN Biotechnology, 2023, 2, 106-119
0.615Citations (PDF)
7Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development4.225Citations (PDF)
8IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data
PLoS Computational Biology, 2022, 18, e1009907
1.926Citations (PDF)
9DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells
Science Advances, 2022, 8,
8.147Citations (PDF)
10Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells3.617Citations (PDF)
11Highly efficient reprogrammable mouse lines with integrated reporters to track the route to pluripotency5.28Citations (PDF)
12Microdroplet-based one-step RT-PCR for ultrahigh throughput single-cell multiplex gene expression analysis and rare cell detection
Scientific Reports, 2021, 11,
2.730Citations (PDF)
13Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm
Scientific Reports, 2021, 11,
2.716Citations (PDF)
14Process evolution in cell and gene therapy from discovery to commercialization1.412Citations (PDF)
15Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study
Lancet Haematology,the, 2020, 7, e134-e145
7.5195Citations (PDF)
16A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength
Scientific Reports, 2020, 10,
2.7110Citations (PDF)
17Functional arrays of human pluripotent stem cell-derived cardiac microtissues
Scientific Reports, 2020, 10,
2.743Citations (PDF)
18Context-explorer: Analysis of spatially organized protein expression in high-throughput screens
PLoS Computational Biology, 2019, 15, e1006384
1.911Citations (PDF)
19Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias
Stem Cell Reports, 2019, 12, 967-981
3.0307Citations (PDF)
20Cell competition during reprogramming gives rise to dominant clones
Science, 2019, 364,
26.1104Citations (PDF)
21Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors
Cell Reports, 2019, 26, 2078-2087.e3
4.439Citations (PDF)
22High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning
PLoS Biology, 2019, 17, e3000081
3.142Citations (PDF)
23Chemically controlled aggregation of pluripotent stem cells
Biotechnology and Bioengineering, 2018, 115, 2061-2066
2.724Citations (PDF)
24Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions3.659Citations (PDF)
25A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies
Nature, 2018, 553, 515-520
30.6327Citations (PDF)
26FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors
Stem Cell Reports, 2018, 10, 87-100
3.039Citations (PDF)
27Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?2.6334Citations (PDF)
28Stem cell bioengineering: building from stem cell biology
Nature Reviews Genetics, 2018, 19, 595-614
30.197Citations (PDF)
29Modulating cell state to enhance suspension expansion of human pluripotent stem cells5.233Citations (PDF)
30Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1
Nature Methods, 2017, 14, 531-538
13.1133Citations (PDF)
31Steric Hindrance Assay for Secreted Factors in Stem Cell Culture
ACS Sensors, 2017, 2, 495-500
7.117Citations (PDF)
32Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence10.822Citations (PDF)
33Engineering cell fitness: lessons for regenerative medicine4.727Citations (PDF)
34A stepwise model of Reaction-Diffusion and Positional-Information governs self-organized human peri-gastrulation-like patterning2.1140Citations (PDF)
35Synthetic gene circuits and cellular decision-making in human pluripotent stem cells1.230Citations (PDF)
36Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell–mediated TNFα signaling8.725Citations (PDF)
37Two-dimensional arrays of cell-laden polymer hydrogel modules
Biomicrofluidics, 2016, 10,
1.614Citations (PDF)
38A 17-gene stemness score for rapid determination of risk in acute leukaemia
Nature, 2016, 540, 433-437
30.6852Citations (PDF)
39Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks
Neuron, 2016, 91, 988-1004
8.246Citations (PDF)
40Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform2.737Citations (PDF)
41Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles
Cell Reports, 2016, 14, 3001-3018
4.4201Citations (PDF)
42miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells
Cancer Cell, 2016, 29, 214-228
28.4249Citations (PDF)
43Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture
PLoS ONE, 2015, 10, e0137392
1.515Citations (PDF)
44The microwell-mesh: A novel device and protocol for the high throughput manufacturing of cartilage microtissues
Biomaterials, 2015, 62, 1-12
9.578Citations (PDF)
45PI3K Phosphorylation Is Linked to Improved Electrical Excitability in an In Vitro Engineered Heart Tissue Disease Model System
Tissue Engineering - Part A, 2015, 21, 2379-2389
1.910Citations (PDF)
46CD24 tracks divergent pluripotent states in mouse and human cells10.888Citations (PDF)
47LIF signaling in stem cells and development
Development (Cambridge), 2015, 142, 2230-2236
2.1124Citations (PDF)
48A Mass Spectrometric-Derived Cell Surface Protein Atlas
PLoS ONE, 2015, 10, e0121314
1.5468Citations (PDF)
49Transforming the Promise of Pluripotent Stem Cell-Derived Cardiomyocytes to a Therapy: Challenges and Solutions for Clinical Trials
Canadian Journal of Cardiology, 2014, 30, 1335-1349
1.428Citations (PDF)
50Genome-wide characterization of the routes to pluripotency
Nature, 2014, 516, 198-206
30.6200Citations (PDF)
51A Global Assessment of Stem Cell Engineering
Tissue Engineering - Part A, 2014, 20, 2575-2589
1.98Citations (PDF)
52Real‐time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures
Biotechnology and Bioengineering, 2014, 111, 1258-1264
2.715Citations (PDF)
53Intercellular network structure and regulatory motifs in the human hematopoietic system3.676Citations (PDF)
54Blood stem cell fate regulation by Delta-1–mediated rewiring of IL-6 paracrine signaling
Blood, 2014, 123, 650-658
3.623Citations (PDF)
55Local BMP-SMAD1 Signaling Increases LIF Receptor-Dependent STAT3 Responsiveness and Primed-to-Naive Mouse Pluripotent Stem Cell Conversion Frequency
Stem Cell Reports, 2014, 3, 156-168
3.025Citations (PDF)
56High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias
Nature Methods, 2013, 10, 1225-1231
13.164Citations (PDF)
57Blood stem cell products: Toward sustainable benchmarks for clinical translation
BioEssays, 2013, 35, 201-210
1.718Citations (PDF)
58High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations2.740Citations (PDF)
59Integrative network analysis of signaling in human CD34+ hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC‐MS/MS and pathway mapping
Proteomics, 2013, 13, 1325-1333
2.116Citations (PDF)
60Design and formulation of functional pluripotent stem cell-derived cardiac microtissues5.2289Citations (PDF)
61PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions
PLoS Computational Biology, 2012, 8, e1002838
1.9119Citations (PDF)
62Regulated Expression and Role of c-Myb in the Cardiovascular-Directed Differentiation of Mouse Embryonic Stem Cells
Circulation Research, 2012, 110, 253-264
8.612Citations (PDF)
63Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells5.264Citations (PDF)
64A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues
Tissue Engineering - Part A, 2012, 18, 910-919
1.9406Citations (PDF)
65Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling
Cell Stem Cell, 2012, 10, 218-229
11.6244Citations (PDF)
66Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures
Nature Methods, 2012, 9, 509-516
13.1107Citations (PDF)
67Tissue engineering 2.0: guiding self-organization during pluripotent stem cell differentiation4.732Citations (PDF)
68Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK–STAT signaling1.412Citations (PDF)
69Systematic engineering of 3D pluripotent stem cell niches to guide blood development
Biomaterials, 2012, 33, 1271-1280
9.546Citations (PDF)
70Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics2.754Citations (PDF)
71Engineered Heart Tissue Model of Diabetic Myocardium
Tissue Engineering - Part A, 2011, 17, 1869-1878
1.929Citations (PDF)
72High-throughput combinatorial cell co-culture using microfluidics1.4193Citations (PDF)
73An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming
Cell, 2011, 147, 132-146
23.4375Citations (PDF)
74Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment2.722Citations (PDF)
75Creation of mouse embryonic stem cell-derived cardiac cell sheets
Biomaterials, 2011, 32, 7355-7362
9.593Citations (PDF)
76Incorporation of biomaterials in multicellular aggregates modulates pluripotent stem cell differentiation
Biomaterials, 2011, 32, 48-56
9.5164Citations (PDF)
77High-throughput generation of hydrogel microbeads with varying elasticity for cell encapsulation
Biomaterials, 2011, 32, 1477-1483
9.5206Citations (PDF)
78Geometric Control of Cardiomyogenic Induction in Human Pluripotent Stem Cells
Tissue Engineering - Part A, 2011, 17, 1901-1909
1.981Citations (PDF)
79Enhanced Human Hematopoietic Stem Cell Self-Renewal Enabled by Controlling Feedback Signaling From Lineage Committed Cells
Blood, 2011, 118, 1274-1274
3.65Citations (PDF)
80The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells
Biomaterials, 2010, 31, 8262-8270
9.574Citations (PDF)
81Enabling stem cell therapies through synthetic stem cell–niche engineering6.6166Citations (PDF)
82Synthetic Peptide Arrays for Pathway-Level Protein Monitoring by Liquid Chromatography-Tandem Mass Spectrometry3.215Citations (PDF)
83Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue5.284Citations (PDF)
84Dynamic interaction networks in a hierarchically organized tissue3.6134Citations (PDF)
85Cell–cell interaction networks regulate blood stem and progenitor cell fate3.6114Citations (PDF)
86Generation of human embryonic stem cell‐derived mesoderm and cardiac cells using size‐specified aggregates in an oxygen‐controlled bioreactor2.7216Citations (PDF)
87An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures2.711Citations (PDF)
88Alternative Induced Pluripotent Stem Cell Characterization Criteria for In Vitro Applications
Cell Stem Cell, 2009, 4, 198-199
11.664Citations (PDF)
89Growth Factors, Matrices, and Forces Combine and Control Stem Cells
Science, 2009, 324, 1673-1677
26.12,579Citations (PDF)
90Manipulation of Signaling Thresholds in “Engineered Stem Cell Niches” Identifies Design Criteria for Pluripotent Stem Cell Screens
PLoS ONE, 2009, 4, e6438
1.563Citations (PDF)
91Enhancement of Soluble Transcription Factor (TAT-HOXB4 and TAT-NUP98HOXA10HD) - Mediated Human Hematopoietic Stem Cell Self-Renewal by Minimizing Inhibitory Endogenous Signalling.
Blood, 2009, 114, 1493-1493
3.60Citations (PDF)
92Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories
Stem Cells, 2008, 26, 2300-2310
2.7439Citations (PDF)
93Soluble Flt-1 Regulates Flk-1 Activation to Control Hematopoietic and Endothelial Development in an Oxygen-Responsive Manner
Stem Cells, 2008, 26, 2832-2842
2.733Citations (PDF)
94Don't Look: Growing Clonal Versus Nonclonal Neural Stem Cell Colonies
Stem Cells, 2008, 26, 2938-2944
2.7150Citations (PDF)
95TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
Nature Cell Biology, 2008, 10, 837-848
12.6633Citations (PDF)
96Functional immobilization of signaling proteins enables control of stem cell fate
Nature Methods, 2008, 5, 645-650
13.1193Citations (PDF)
97Analysis of the temporal and concentration-dependent effects of BMP-4, VEGF, and TPO on development of embryonic stem cell–derived mesoderm and blood progenitors in a defined, serum-free media
Experimental Hematology, 2008, 36, 1186-1198
0.625Citations (PDF)
98The Systematic Production of Cells for Cell Therapies
Cell Stem Cell, 2008, 3, 369-381
11.6301Citations (PDF)
99Seeding Bioreactor-Produced Embryonic Stem Cell-Derived Cardiomyocytes on Different Porous, Degradable, Polyurethane Scaffolds Reveals the Effect of Scaffold Architecture on Cell Morphology
Tissue Engineering - Part A, 2008, 14, 369-378
1.968Citations (PDF)
100Reproducible, Ultra High-Throughput Formation of Multicellular Organization from Single Cell Suspension-Derived Human Embryonic Stem Cell Aggregates
PLoS ONE, 2008, 3, e1565
1.5384Citations (PDF)
101LIF‐mediated control of embryonic stem cell self‐renewal emerges due to an autoregulatory loop
FASEB Journal, 2007, 21, 2020-2032
2.363Citations (PDF)
102Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control1.955Citations (PDF)
103Prediction and Testing of Novel Transcriptional Networks Regulating Embryonic Stem Cell Self-Renewal and Commitment
Cell Stem Cell, 2007, 1, 71-86
11.6103Citations (PDF)
104Niche‐mediated control of human embryonic stem cell self‐renewal and differentiation
EMBO Journal, 2007, 26, 4744-4755
5.1386Citations (PDF)
105Phenotypic Analysis of Human Embryonic Stem Cells1.518Citations (PDF)
106Engineering cardiac healing using embryonic stem cell-derived cardiac cell seeded constructs5.810Citations (PDF)
107Spatial Organization of Embryonic Stem Cell Responsiveness to Autocrine Gp130 Ligands Reveals an Autoregulatory Stem Cell Niche
Stem Cells, 2006, 24, 2538-2548
2.758Citations (PDF)
108Clinically Relevant Expansion of Hematopoietic Stem Cells with Conserved Function in a Single-Use, Closed-System Bioprocess1.651Citations (PDF)
109Understanding cellular networks to improve hematopoietic stem cell expansion cultures4.734Citations (PDF)
110Polyurethane films seeded with embryonic stem cell-derived cardiomyocytes for use in cardiac tissue engineering applications
Biomaterials, 2005, 26, 7377-7386
9.5174Citations (PDF)
111Shear-Controlled Single-Step Mouse Embryonic Stem Cell Expansion and Embryoid Body-Based Differentiation
Stem Cells, 2005, 23, 1333-1342
2.7225Citations (PDF)
112Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion
Experimental Hematology, 2005, 33, 1229-1239
0.660Citations (PDF)
113Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: Oxygen-mediated enhancement of cardiomyocyte output2.7146Citations (PDF)
114Culture development for human embryonic stem cell propagation: molecular aspects and challenges4.777Citations (PDF)
115Clonal evolution of stem and differentiated cells can be predicted by integrating cell-intrinsic and -extrinsic parameters1.916Citations (PDF)
116Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling5.2103Citations (PDF)
117Sustained In Vitro Expansion of Bone Progenitors Is Cell Density Dependent
Stem Cells, 2004, 22, 39-50
2.776Citations (PDF)
118Controlled, Scalable Embryonic Stem Cell Differentiation Culture
Stem Cells, 2004, 22, 275-282
2.7285Citations (PDF)
119Quantitative screening of embryonic stem cell differentiation: Endoderm formation as a model2.743Citations (PDF)
120Signal processing underlying extrinsic control of stem cell fate1.417Citations (PDF)
121Title is missing!
Cytotechnology, 2003, 41, 75-92
1.350Citations (PDF)
122Adult human bone marrow–derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion
Experimental Hematology, 2003, 31, 723-732
0.6121Citations (PDF)
123Fluorescence activated cell sorting reveals heterogeneous and cell non‐autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations1.818Citations (PDF)
124Supplementation-dependent differences in the rates of embryonic stem cell self-renewal, differentiation, and apoptosis2.749Citations (PDF)
125Scalable Production of Embryonic Stem Cell-Derived Cardiomyocytes
Tissue Engineering, 2003, 9, 767-778
4.8272Citations (PDF)
126Two-Color Image Analysis Discriminates between Mineralized and Unmineralized Bone Nodules In Vitro
BioTechniques, 2003, 34, 1188-1198
2.710Citations (PDF)
127Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems2.7332Citations (PDF)
128Ligand/Receptor Signaling Threshold (LIST) Model Accounts for gp130-Mediated Embryonic Stem Cell Self-Renewal Responses to LIF and HIL-6
Stem Cells, 2002, 20, 119-138
2.789Citations (PDF)
129Modeling Stem Cell Development by Retrospective Analysis of Gene Expression Profiles in Single Progenitor-Derived Colonies
Stem Cells, 2002, 20, 230-240
2.740Citations (PDF)
130Stem Cell Bioengineering6.0124Citations (PDF)
131Controlling Culture Dynamics for the Expansion of Hematopoietic Stem Cells1.823Citations (PDF)
132Advances in hematopoietic stem cell culture4.734Citations (PDF)
133Ontogeny‐associated changes in the cytokine responses of primitive human haemopoietic cells
British Journal of Haematology, 1998, 101, 770-778
1.795Citations (PDF)
134Cytokine manipulation of primitive human hematopoietic cell self-renewal5.2281Citations (PDF)
135Expansion of Hematopoietic Progenitor Cell Populations in Stirred Suspension Bioreactors of Normal Human Bone Marrow Cells
Nature Biotechnology, 1994, 12, 909-914
19.7104Citations (PDF)
136Unusual surface tension behavior of an aqueous solution of gramicidin S7.92Citations (PDF)
137Title is missing!
0
1Citations (PDF)
138Innate lymphoid cells in the spotlight: from biomarkers to blueprint for innovative immunotherapy3.315Citations (PDF)