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416 peer-reviewed articles • 28,600 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1A Robust and Automated Platform for Charge Detection Mass Spectrometry of Megadalton Biotherapeutics
Analytical Chemistry, 2025, 97, 4549-4555
6.56Citations (PDF)
2Proteoform-predictor: Increasing the Phylogenetic Reach of Top-Down Proteomics
Journal of Proteome Research, 2025, 24, 1861-1870
3.43Citations (PDF)
3Capillary Zone Electrophoresis-Mass Spectrometry of Intact G Protein-Coupled Receptors Enables Proteoform Profiling
Analytical Chemistry, 2025, 97, 7307-7316
6.55Citations (PDF)
4Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine7.56Citations (PDF)
5The Proteoform Landscape of Tau from the Human Brain
Journal of Proteome Research, 2025, 24, 2916-2925
3.416Citations (PDF)
6Wavelength Dependence of Intact Protein Extraction Using Femtosecond Laser Ablation4.21Citations (PDF)
7Improved Signal Processing for Mass Shifting Ions in Charge Detection Mass Spectrometry2.612Citations (PDF)
8Terpenoid balance in Aspergillus nidulans unveiled by heterologous squalene synthase expression
Science Advances, 2024, 10,
10.98Citations (PDF)
9Precise Readout of MEK1 Proteoforms upon MAPK Pathway Modulation by Individual Ion Mass Spectrometry
Analytical Chemistry, 2024, 96, 4455-4462
6.510Citations (PDF)
10Single Cell Analysis of Proteoforms
Journal of Proteome Research, 2024, 23, 1883-1893
3.425Citations (PDF)
11Design, Synthesis, and Mechanistic Studies of (R)-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase
ACS Chemical Biology, 2024, 19, 1066-1081
3.75Citations (PDF)
12MSModDetector: a tool for detecting mass shifts and post-translational modifications in individual ion mass spectrometry data
Bioinformatics, 2024, 40,
4.72Citations (PDF)
13Top-down mass spectrometry of native proteoforms and their complexes: a community study
Nature Methods, 2024, 21, 2388-2396
24.638Citations (PDF)
14A multi-iron enzyme installs copper-binding oxazolone/thioamide pairs on a nontypeable Haemophilus influenzae virulence factor7.523Citations (PDF)
15Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster
Metabolomics, 2024, 20,
2.811Citations (PDF)
16Characterization of the Antibody Response to SARS-CoV-2 Infection in COVID-19 Transplant versus Nontransplant Recipients by Ig-MS
Journal of Proteome Research, 2024, 23, 3944-3957
3.40Citations (PDF)
17Deep Profiling of Plasma Proteoforms with Engineered Nanoparticles for Top-Down Proteomics
Journal of Proteome Research, 2024, 23, 4694-4703
3.428Citations (PDF)
18Temporal regulation of gene expression through integration of p53 dynamics and modifications
Science Advances, 2024, 10,
10.95Citations (PDF)
19Top-Down Proteomics Identifies Plasma Proteoform Signatures of Liver Cirrhosis Progression3.015Citations (PDF)
20Top-Down Stability of Proteins from Rates of Oxidation (TD-SPROX) Approach for Measuring Proteoform-Specific Folding Stability
Analytical Chemistry, 2024, 96, 19597-19604
6.58Citations (PDF)
21Preparative Electrophoresis for HDL Particle Size Separation and Intact-Mass Apolipoprotein Proteoform Analysis
Journal of Proteome Research, 2023, 22, 1455-1465
3.48Citations (PDF)
22Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs
Nature Chemical Biology, 2023, 19, 846-854
11.851Citations (PDF)
23ProSight Native: Defining Protein Complex Composition from Native Top-Down Mass Spectrometry Data
Journal of Proteome Research, 2023, 22, 2660-2668
3.439Citations (PDF)
24Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 18.828Citations (PDF)
25Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging
Nature Methods, 2023, 20, 1174-1178
24.645Citations (PDF)
26Identification of Splice Variants and Isoforms in Transcriptomics and Proteomics4.934Citations (PDF)
27Automated imaging and identification of proteoforms directly from ovarian cancer tissue13.729Citations (PDF)
28Advancing Intact Protein Quantitation with Updated Deconvolution Routines
Analytical Chemistry, 2023, 95, 14954-14962
6.56Citations (PDF)
29Immunocomplexed Antigen Capture and Identification by Native Top-Down Mass Spectrometry2.63Citations (PDF)
30Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease
Journal of Proteome Research, 2023, 22, 3475-3488
3.46Citations (PDF)
31Mass spectrometry-based proteomics for advancing solid organ transplantation research1.010Citations (PDF)
32Determining Collisional Cross Sections from Ion Decay with Individual Ion Mass Spectrometry2.62Citations (PDF)
33Determining Collisional Cross Sections from Ion Decay with Individual Ion Mass Spectrometry2.66Citations (PDF)
34The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells
Science, 2022, 375, 411-418
36.3137Citations (PDF)
35Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire
Journal of Proteome Research, 2022, 21, 274-288
3.423Citations (PDF)
36Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase15.013Citations (PDF)
37A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis7.541Citations (PDF)
38ProSight Annotator: Complete control and customization of protein entries in UniProt XML files
Proteomics, 2022, 22,
3.18Citations (PDF)
39The Human Proteoform Atlas: a FAIR community resource for experimentally derived proteoforms
Nucleic Acids Research, 2022, 50, D526-D533
15.536Citations (PDF)
40Mapping the Proteoform Landscape of Five Human Tissues
Journal of Proteome Research, 2022, 21, 1299-1310
3.452Citations (PDF)
41SETD2 Haploinsufficiency Enhances Germinal Center–Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis
Cancer Discovery, 2022, 12, 1782-1803
25.130Citations (PDF)
42Proteoform‐Selective Imaging of Tissues Using Mass Spectrometry**14.446Citations (PDF)
43An efficient cell‐free protein synthesis platform for producing proteins with pyrrolysine‐based noncanonical amino acids3.316Citations (PDF)
44Innenrücktitelbild: Proteoform‐Selective Imaging of Tissues Using Mass Spectrometry (Angew. Chem. 29/2022)
Angewandte Chemie, 2022, 134,
1.40Citations (PDF)
45Native Mass Spectrometry at the Convergence of Structural Biology and Compositional Proteomics
Accounts of Chemical Research, 2022, 55, 1928-1937
17.028Citations (PDF)
46C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways7.523Citations (PDF)
47Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation
ACS Chemical Biology, 2022, 17, 2769-2780
3.714Citations (PDF)
48Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry
Science Advances, 2022, 8,
10.964Citations (PDF)
49SPT6 functions in transcriptional pause/release via PAF1C recruitment
Molecular Cell, 2022, 82, 3412-3423.e5
13.367Citations (PDF)
50Venom characterization of the Brazilian Pampa snake Bothrops pubescens by top-down and bottom-up proteomics
Toxicon, 2022, 220, 106937
2.16Citations (PDF)
51Divergent Antibody Repertoires Found for Omicron versus Wuhan SARS-CoV-2 Strains Using Ig-MS
Journal of Proteome Research, 2022, 21, 2987-2997
3.48Citations (PDF)
52Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor15.019Citations (PDF)
53Isotopic Resolution of Protein Complexes up to 466 kDa Using Individual Ion Mass Spectrometry
Analytical Chemistry, 2021, 93, 2723-2727
6.556Citations (PDF)
54Standard procedures for native CZE‐MS of proteins and protein complexes up to 800 kDa
Electrophoresis, 2021, 42, 1050-1059
2.639Citations (PDF)
55Metabolomics and genomics in natural products research: complementary tools for targeting new chemical entities
Natural Product Reports, 2021, 38, 2041-2065
10.6147Citations (PDF)
56In vitro-Constructed Ribosomes Enable Multi-site Incorporation of Noncanonical Amino Acids into Proteins
Biochemistry, 2021, 60, 161-169
2.416Citations (PDF)
57Decoding the protein composition of whole nucleosomes with Nuc-MS
Nature Methods, 2021, 18, 303-308
24.666Citations (PDF)
58Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis–Top-Down Mass Spectrometry
Analytical Chemistry, 2021, 93, 5151-5160
6.541Citations (PDF)
59Deeper Protein Identification Using Field Asymmetric Ion Mobility Spectrometry in Top-Down Proteomics
Analytical Chemistry, 2021, 93, 6323-6328
6.556Citations (PDF)
60Remarkable and Unexpected Mechanism for (S)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase15.016Citations (PDF)
61New Interface for Faster Proteoform Analysis: Immunoprecipitation Coupled with SampleStream-Mass Spectrometry2.624Citations (PDF)
62An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes7.5172Citations (PDF)
63Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase15.012Citations (PDF)
64Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells
FEBS Journal, 2021, 288, 6683-6699
5.420Citations (PDF)
65Reassembling protein complexes after controlled disassembly by top-down mass spectrometry in native mode1.616Citations (PDF)
66Spectrum of Apolipoprotein AI and Apolipoprotein AII Proteoforms and Their Associations With Indices of Cardiometabolic Health: The CARDIA Study4.028Citations (PDF)
67Characterization of a Copper-Chelating Natural Product from the Methanotroph Methylosinus sp. LW3
Biochemistry, 2021, 60, 2845-2850
2.411Citations (PDF)
68SPT5 stabilization of promoter-proximal RNA polymerase II
Molecular Cell, 2021, 81, 4413-4424.e5
13.3103Citations (PDF)
69Should LC-MS/MS Be the Reference Measurement Procedure to Determine Protein Concentrations in Human Samples?
Clinical Chemistry, 2021, 67, 466-471
1.120Citations (PDF)
70Development of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and middle-down de novo sequencing2.38Citations (PDF)
71The Human Proteoform Project: Defining the human proteome
Science Advances, 2021, 7,
10.9231Citations (PDF)
72Novel Interface for High-Throughput Analysis of Biotherapeutics by Electrospray Mass Spectrometry
Analytical Chemistry, 2020, 92, 2186-2193
6.547Citations (PDF)
73Discovery of the Biosynthetic Machinery for Stravidins, Biotin Antimetabolites
ACS Chemical Biology, 2020, 15, 1134-1140
3.713Citations (PDF)
74In the fungus where it happens: History and future propelling Aspergillus nidulans as the archetype of natural products research
Fungal Genetics and Biology, 2020, 144, 103477
2.163Citations (PDF)
75Streptomyces buecherae sp. nov., an actinomycete isolated from multiple bat species
Antonie Van Leeuwenhoek, 2020, 113, 2213-2221
1.513Citations (PDF)
76Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma11.332Citations (PDF)
77Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry2.6104Citations (PDF)
78Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds
MBio, 2020, 11,
4.420Citations (PDF)
79Genome Mining and Metabolomics Uncover a Rare d-Capreomycidine Containing Natural Product and Its Biosynthetic Gene Cluster
ACS Chemical Biology, 2020, 15, 3013-3020
3.710Citations (PDF)
80Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
Cancer Cell, 2020, 37, 655-673.e11
33.0152Citations (PDF)
81The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing
Nature Cancer, 2020, 1, 653-664
22.562Citations (PDF)
82Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top-Down Mass Spectrometry
Journal of Proteome Research, 2020, 19, 1346-1350
3.469Citations (PDF)
83Voltage Rollercoaster Filtering of Low-Mass Contaminants During Native Protein Analysis2.622Citations (PDF)
84NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle13.7101Citations (PDF)
85A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid15.029Citations (PDF)
86Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes
Nature Methods, 2020, 17, 391-394
24.6186Citations (PDF)
87Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics3.070Citations (PDF)
88Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype
Journal of Proteome Research, 2020, 19, 938-948
3.413Citations (PDF)
89Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions2.649Citations (PDF)
90A MUC16 IgG Binding Activity Selects for a Restricted Subset of IgG Enriched for Certain Simian Immunodeficiency Virus Epitope Specificities3.65Citations (PDF)
91Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
Nature, 2020, 589, 299-305
37.9248Citations (PDF)
92Mechanism-Based Design of 3-Amino-4-Halocyclopentenecarboxylic Acids as Inactivators of GABA Aminotransferase
ACS Medicinal Chemistry Letters, 2020, 11, 1949-1955
3.312Citations (PDF)
93Using 10,000 Fragment Ions to Inform Scoring in Native Top-down Proteomics2.628Citations (PDF)
94Targeted detection and quantitation of histone modifications from 1,000 cells
PLoS ONE, 2020, 15, e0240829
2.35Citations (PDF)
95Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes2.616Citations (PDF)
96Mo-, V-, and Fe-Nitrogenases Use a Universal Eight-Electron Reductive-Elimination Mechanism To Achieve N 2 Reduction
Biochemistry, 2019, 58, 3293-3301
2.4143Citations (PDF)
97A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
Cancer Discovery, 2019, 9, 1438-1451
25.1103Citations (PDF)
98Mechanism of Inactivation of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid15.028Citations (PDF)
99Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding
Journal of Biological Chemistry, 2019, 294, 12459-12471
2.219Citations (PDF)
100Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry
MAbs, 2019, 11, 1351-1357
10.231Citations (PDF)
101A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli
Cell Chemical Biology, 2019, 26, 1743-1754.e9
6.281Citations (PDF)
102A five-level classification system for proteoform identifications
Nature Methods, 2019, 16, 939-940
24.686Citations (PDF)
103Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
Journal of Proteome Research, 2019, 18, 3999-4012
3.415Citations (PDF)
104Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase13.798Citations (PDF)
105Identification and Quantification of Proteoforms by Mass Spectrometry
Proteomics, 2019, 19,
3.1189Citations (PDF)
106Standard Proteoforms and Their Complexes for Native Mass Spectrometry2.652Citations (PDF)
107Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas
Clinical Cancer Research, 2019, 25, 5271-5283
6.875Citations (PDF)
108Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis
Blood, 2019, 134, 1619-1631
4.851Citations (PDF)
109Proton Transfer Charge Reduction Enables High-Throughput Top-Down Analysis of Large Proteoforms
Analytical Chemistry, 2019, 91, 15732-15739
6.590Citations (PDF)
110USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia
Clinical Cancer Research, 2019, 25, 222-239
6.888Citations (PDF)
111A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies
Journal of Neurochemistry, 2019, 148, 822-836
3.824Citations (PDF)
112Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics3.043Citations (PDF)
113Measurement of Individual Ions Sharply Increases the Resolution of Orbitrap Mass Spectra of Proteins
Analytical Chemistry, 2019, 91, 2776-2783
6.587Citations (PDF)
114A computational framework to explore large-scale biosynthetic diversity
Nature Chemical Biology, 2019, 16, 60-68
11.81,037Citations (PDF)
115Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics
ACS Chemical Biology, 2018, 13, 1029-1037
3.749Citations (PDF)
116Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains
Analytical Chemistry, 2018, 90, 3802-3810
6.534Citations (PDF)
117β-Glucocerebrosidase Modulators Promote Dimerization of β-Glucocerebrosidase and Reveal an Allosteric Binding Site15.048Citations (PDF)
118Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins
Biochemistry, 2018, 57, 3515-3523
2.421Citations (PDF)
119Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk7.596Citations (PDF)
120Identification of the First Diketomorpholine Biosynthetic Pathway Using FAC-MS Technology
ACS Chemical Biology, 2018, 13, 1142-1147
3.733Citations (PDF)
121A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity
Journal of Proteome Research, 2018, 17, 2156-2164
3.440Citations (PDF)
122Mechanism of N2 Reduction Catalyzed by Fe-Nitrogenase Involves Reductive Elimination of H2
Biochemistry, 2018, 57, 701-710
2.4107Citations (PDF)
123Total Synthesis of Tambromycin Enabled by Indole C–H Functionalization
Organic Letters, 2018, 20, 2369-2373
4.834Citations (PDF)
124Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids13.7213Citations (PDF)
125Interrogation of Benzomalvin Biosynthesis Using Fungal Artificial Chromosomes with Metabolomic Scoring (FAC-MS): Discovery of a Benzodiazepine Synthase Activity
Biochemistry, 2018, 57, 3237-3243
2.427Citations (PDF)
126Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria13.762Citations (PDF)
127Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells
PLoS ONE, 2018, 13, e0203351
2.34Citations (PDF)
128The unique biomineralization transcriptome and proteome of Lytechinus variegatus teeth2.43Citations (PDF)
129Estimating the Distribution of Protein Post-Translational Modification States by Mass Spectrometry
Journal of Proteome Research, 2018, 17, 2727-2734
3.436Citations (PDF)
130The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins
Analytical Chemistry, 2018, 90, 8553-8560
6.543Citations (PDF)
131Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques
Analytical Chemistry, 2018, 90, 8421-8429
6.5149Citations (PDF)
132Natural products from thioester reductase containing biosynthetic pathways
Natural Product Reports, 2018, 35, 847-878
10.694Citations (PDF)
133An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia
Oncogene, 2018, 38, 671-686
6.555Citations (PDF)
134Coupling Fluorescence‐Activated Cell Sorting and Targeted LC‐MS/MS for Epi‐Proteomic Analysis of Normal Leukocytes
FASEB Journal, 2018, 32,
0.60Citations (PDF)
135Expansion for theBrachylophosaurus canadensisCollagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein
Journal of Proteome Research, 2017, 16, 920-932
3.492Citations (PDF)
136Chromatographic efficiency and selectivity in top-down proteomics of histones2.69Citations (PDF)
137Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
Nature Medicine, 2017, 23, 493-500
33.0408Citations (PDF)
138Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools
Biochemistry, 2017, 56, 1645-1655
2.432Citations (PDF)
139Substrate Trapping in the Siderophore Tailoring Enzyme PvdQ
ACS Chemical Biology, 2017, 12, 643-647
3.76Citations (PDF)
140High-Throughput Analysis of Intact Human Proteins Using UVPD and HCD on an Orbitrap Mass Spectrometer
Journal of Proteome Research, 2017, 16, 2072-2079
3.486Citations (PDF)
141A scalable platform to identify fungal secondary metabolites and their gene clusters
Nature Chemical Biology, 2017, 13, 895-901
11.8188Citations (PDF)
142Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry2.659Citations (PDF)
143Modulation of Protein Fragmentation Through Carbamylation of Primary Amines2.621Citations (PDF)
144Translation system engineering in Escherichia coli enhances non‐canonical amino acid incorporation into proteins
Biotechnology and Bioengineering, 2017, 114, 1074-1086
3.957Citations (PDF)
145A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation
Genes and Development, 2017, 31, 2003-2014
4.668Citations (PDF)
146Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
Nature Genetics, 2017, 49, 1647-1653
25.2219Citations (PDF)
147UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition
Cell Reports, 2017, 21, 628-640
6.3128Citations (PDF)
148Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin
Analytical Chemistry, 2017, 89, 10711-10716
6.518Citations (PDF)
149Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5′-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover
Biochemistry, 2017, 56, 4951-4961
2.418Citations (PDF)
150Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain3.4155Citations (PDF)
151Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring
Nature Chemical Biology, 2017, 13, 1063-1065
11.865Citations (PDF)
152Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer
Journal of Proteome Research, 2017, 16, 609-618
3.484Citations (PDF)
153In Vitro Reconstruction of Nonribosomal Peptide Biosynthesis Directly from DNA Using Cell-Free Protein Synthesis
ACS Synthetic Biology, 2017, 6, 39-44
4.196Citations (PDF)
154Top-down characterization of endogenous protein complexes with native proteomics
Nature Chemical Biology, 2017, 14, 36-41
11.8159Citations (PDF)
155Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence
Nature Genetics, 2017, 50, 62-72
25.2193Citations (PDF)
156High‐Throughput Natural Products Discovery in Fungi Using FAC‐MS Technology
FASEB Journal, 2017, 31,
0.60Citations (PDF)
157Native Proteomics: A New Approach to Protein Complex Discovery and Characterization
FASEB Journal, 2017, 31,
0.62Citations (PDF)
158GENT-51. EPIGENETIC PROFILING REVEALS A UNIQUE HISTONE CODE IN CHORDOMA
Neuro-Oncology, 2016, 18, vi85-vi85
1.00Citations (PDF)
159Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection
Proteomics, 2016, 16, 2048-2058
3.124Citations (PDF)
160The Search Engine for Multi‐Proteoform Complexes: An Online Tool for the Identification and Stoichiometry Determination of Protein Complexes3.37Citations (PDF)
161Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea
Journal of Biological Chemistry, 2016, 291, 8109-8120
2.230Citations (PDF)
162A researcher's guide to mass spectrometry‐based proteomics
Proteomics, 2016, 16, 2435-2443
3.143Citations (PDF)
163Characterization of Methanobactin from Methylosinus sp. LW415.042Citations (PDF)
164Epiproteomics: quantitative analysis of histone marks and codes by mass spectrometry5.872Citations (PDF)
165Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations
ACS Chemical Biology, 2016, 11, 3452-3460
3.752Citations (PDF)
166CN-GELFrEE - Clear Native Gel-eluted Liquid Fraction Entrapment Electrophoresis0.310Citations (PDF)
167Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"
Nature Medicine, 2016, 22, 578-579
33.08Citations (PDF)
168Progress in Top-Down Proteomics and the Analysis of Proteoforms7.0520Citations (PDF)
169New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans
ACS Chemical Biology, 2016, 11, 2117-2123
3.768Citations (PDF)
170Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics3.082Citations (PDF)
171An informatic framework for decoding protein complexes by top-down mass spectrometry
Nature Methods, 2016, 13, 237-240
24.663Citations (PDF)
172Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer
ACS Central Science, 2016, 2, 99-108
9.2131Citations (PDF)
173Systems Proteomics View of the Endogenous Human Claudin Protein Family
Journal of Proteome Research, 2016, 15, 339-359
3.437Citations (PDF)
174Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa
Journal of Proteome Research, 2016, 15, 976-982
3.498Citations (PDF)
175Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation7.546Citations (PDF)
176Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16
Mucosal Immunology, 2016, 9, 1549-1558
7.048Citations (PDF)
177Targeted analysis of recombinant NF kappa B (RelA/p65) by denaturing and native top down mass spectrometry
Journal of Proteomics, 2016, 134, 76-84
2.410Citations (PDF)
178Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts3.076Citations (PDF)
179Unabridged Analysis of Human Histone H3 by Differential Top-Down Mass Spectrometry Reveals Hypermethylated Proteoforms from MMSET/NSD2 Overexpression3.067Citations (PDF)
180Therapeutic Targeting of the Histone Ubiquitination-Methylation Axis in T Cell Leukemia
Blood, 2016, 128, 1532-1532
4.80Citations (PDF)
181CN-GELFrEE - Clear Native Gel-eluted Liquid Fraction Entrapment Electrophoresis0.31Citations (PDF)
182Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids
Nature Biotechnology, 2015, 33, 1272-1279
29.8284Citations (PDF)
183Probing asymmetric charge partitioning of protein oligomers during tandem mass spectrometry1.69Citations (PDF)
184Redox Metabolites Signal Polymicrobial Biofilm Development via the NapA Oxidative Stress Cascade in Aspergillus
Current Biology, 2015, 25, 29-37
3.692Citations (PDF)
185Tunable Loading of Oligonucleotides with Secondary Structure on Gold Nanoparticles through a pH-Driven Method
Bioconjugate Chemistry, 2015, 26, 279-285
3.830Citations (PDF)
186Native GELFrEE: A New Separation Technique for Biomolecular Assemblies
Analytical Chemistry, 2015, 87, 3032-3038
6.541Citations (PDF)
187Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115)15.036Citations (PDF)
188Reducing protein oxidation in low-flow electrospray enables deeper investigation of proteoforms by top down proteomics
EuPA Open Proteomics, 2015, 8, 40-47
0.010Citations (PDF)
189Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by (S)-2-Amino-5-(2-(methylthio)acetimidamido)pentanoic Acid15.07Citations (PDF)
190Analyzing Internal Fragmentation of Electrosprayed Ubiquitin Ions During Beam-Type Collisional Dissociation2.649Citations (PDF)
191Improving Cell‐Free Protein Synthesis through Genome Engineering of Escherichia coli Lacking Release Factor 1
ChemBioChem, 2015, 16, 844-853
2.683Citations (PDF)
192Design and Mechanism of Tetrahydrothiophene-Based γ-Aminobutyric Acid Aminotransferase Inactivators15.025Citations (PDF)
193Large-Scale Metabolomics Reveals a Complex Response of Aspergillus nidulans to Epigenetic Perturbation
ACS Chemical Biology, 2015, 10, 1535-1541
3.7105Citations (PDF)
194Online Matrix Removal Platform for Coupling Gel-Based Separations to Whole Protein Electrospray Ionization Mass Spectrometry
Journal of Proteome Research, 2015, 14, 2199-2206
3.419Citations (PDF)
195Defining the Neuropeptidome of the Spiny Lobster Panulirus interruptus Brain Using a Multidimensional Mass Spectrometry-Based Platform
Journal of Proteome Research, 2015, 14, 4776-4791
3.426Citations (PDF)
196Fungal artificial chromosomes for mining of the fungal secondary metabolome
BMC Genomics, 2015, 16,
3.388Citations (PDF)
197Top Down Proteomics Reveals Mature Proteoforms Expressed in Subcellular Fractions of the Echinococcus granulosus Preadult Stage
Journal of Proteome Research, 2015, 14, 4805-4814
3.419Citations (PDF)
198Loss of BAP1 function leads to EZH2-dependent transformation
Nature Medicine, 2015, 21, 1344-1349
33.0349Citations (PDF)
199Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid
ACS Chemical Biology, 2015, 10, 2087-2098
3.716Citations (PDF)
200Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis
Journal of Proteome Research, 2015, 14, 5252-5262
3.468Citations (PDF)
201ProSight Lite: Graphical software to analyze top‐down mass spectrometry data
Proteomics, 2015, 15, 1235-1238
3.1236Citations (PDF)
202Allele-Specific Crispr Targeting Reveals Epigenetic and Phenotypic Effects of a MMSET Gain of Function Mutation Found in Relapsed Acute Lymphoblastic Leukemia
Blood, 2015, 126, 437-437
4.83Citations (PDF)
203BAP1 Loss Results in EZH2-Dependent Transformation in Myelodysplastic Syndromes
Blood, 2015, 126, 713-713
4.81Citations (PDF)
204Top-Down Proteomics with Mass Spectrometry Imaging: A Pilot Study towards Discovery of Biomarkers for Neurodevelopmental Disorders
PLoS ONE, 2014, 9, e92831
2.340Citations (PDF)
205Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation
PLoS Genetics, 2014, 10, e1004566
3.2220Citations (PDF)
206Site‐specific human histone H3 methylation stability: fast K4me3 turnover
Proteomics, 2014, 14, 2190-2199
3.138Citations (PDF)
207Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways3.337Citations (PDF)
208Top Down proteomics: Facts and perspectives2.1468Citations (PDF)
209The first pilot project of the consortium for top‐down proteomics: A status report
Proteomics, 2014, 14, 1130-1140
3.197Citations (PDF)
210Applying Label-Free Quantitation to Top Down Proteomics
Analytical Chemistry, 2014, 86, 4961-4968
6.5100Citations (PDF)
211Optimizing capillary electrophoresis for top‐down proteomics of 30–80 kDa proteins
Proteomics, 2014, 14, 1158-1164
3.191Citations (PDF)
212The C-Score: A Bayesian Framework to Sharply Improve Proteoform Scoring in High-Throughput Top Down Proteomics
Journal of Proteome Research, 2014, 13, 3231-3240
3.483Citations (PDF)
213Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Time Scale
Analytical Chemistry, 2014, 86, 2185-2192
6.589Citations (PDF)
214Fragmentation of Integral Membrane Proteins in the Gas Phase
Analytical Chemistry, 2014, 86, 4627-4634
6.531Citations (PDF)
215Autopilot: An Online Data Acquisition Control System for the Enhanced High-Throughput Characterization of Intact Proteins
Analytical Chemistry, 2014, 86, 1485-1492
6.536Citations (PDF)
216Comparing Label-Free Quantitative Peptidomics Approaches to Characterize Diurnal Variation of Peptides in the Rat Suprachiasmatic Nucleus
Analytical Chemistry, 2014, 86, 443-452
6.546Citations (PDF)
217A roadmap for natural product discovery based on large-scale genomics and metabolomics
Nature Chemical Biology, 2014, 10, 963-968
11.8474Citations (PDF)
218Cell-free Protein Synthesis from a Release Factor 1 Deficient Escherichia coli Activates Efficient and Multiple Site-specific Nonstandard Amino Acid Incorporation
ACS Synthetic Biology, 2014, 3, 398-409
4.1146Citations (PDF)
219Loss of the Histone Demethylase UTX Contributes to Multiple Myeloma and Sensitizes Cells to EZH2 Inhibitors
Blood, 2014, 124, 611-611
4.88Citations (PDF)
220Measurement of acetylation turnover at distinct lysines in human histones identifies long-lived acetylation sites13.7116Citations (PDF)
221Large-scale Top-down Proteomics of the Human Proteome: Membrane Proteins, Mitochondria, and Senescence3.0146Citations (PDF)
222Developing top down proteomics to maximize proteome and sequence coverage from cells and tissues5.846Citations (PDF)
223Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics
Journal of Proteomics, 2013, 79, 60-71
2.484Citations (PDF)
224Discovery of the Antibiotic Phosacetamycin via a New Mass Spectrometry-Based Method for Phosphonic Acid Detection
ACS Chemical Biology, 2013, 8, 908-913
3.737Citations (PDF)
225Proteomics Guided Discovery of Flavopeptins: Anti-proliferative Aldehydes Synthesized by a Reductase Domain-Containing Non-ribosomal Peptide Synthetase15.030Citations (PDF)
22625 th ASMS Sanibel Conference on Top Down Mass Spectrometry2.61Citations (PDF)
227Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation15.0347Citations (PDF)
228Top Down Proteomics of Human Membrane Proteins from Enriched Mitochondrial Fractions
Analytical Chemistry, 2013, 85, 1880-1888
6.576Citations (PDF)
229Proteoform: a single term describing protein complexity
Nature Methods, 2013, 10, 186-187
24.61,487Citations (PDF)
230Oncogene‐induced cellular senescence elicits an anti‐Warburg effect
Proteomics, 2013, 13, 2585-2596
3.143Citations (PDF)
231EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Cancer Cell, 2013, 23, 677-692
33.0832Citations (PDF)
232Quantitative Peptidomics for Discovery of Circadian-Related Peptides from the Rat Suprachiasmatic Nucleus
Journal of Proteome Research, 2013, 12, 585-593
3.455Citations (PDF)
233From Protein Complexes to Subunit Backbone Fragments: A Multi-stage Approach to Native Mass Spectrometry
Analytical Chemistry, 2013, 85, 11163-11173
6.5168Citations (PDF)
234Metabolic Perturbation of an Essential Pathway: Evaluation of a Glycine Precursor of Coenzyme A15.07Citations (PDF)
235Gobichelin A and B: mixed-ligandsiderophores discovered using proteomics
MedChemComm, 2013, 4, 233-238
4.535Citations (PDF)
236Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H37.5148Citations (PDF)
237Comparative peptidomics analysis of neural adaptations in rats repeatedly exposed to amphetamine
Journal of Neurochemistry, 2012, 123, 276-287
3.827Citations (PDF)
238High-definition De Novo Sequencing of Crustacean Hyperglycemic Hormone (CHH)-family Neuropeptides3.036Citations (PDF)
239Analysis of Intact Monoclonal Antibody IgG1 by Electron Transfer Dissociation Orbitrap FTMS3.0150Citations (PDF)
240A Cell-Based Approach to the Human Proteome Project2.648Citations (PDF)
241Ion Mobility Separation of Variant Histone Tails Extending to the “Middle-Down” Range
Analytical Chemistry, 2012, 84, 4271-4276
6.543Citations (PDF)
242Robust Analysis of the Yeast Proteome under 50 kDa by Molecular-Mass-Based Fractionation and Top-Down Mass Spectrometry
Analytical Chemistry, 2012, 84, 209-215
6.562Citations (PDF)
243Separation of Variant Methylated Histone Tails by Differential Ion Mobility
Analytical Chemistry, 2012, 84, 6317-6320
6.551Citations (PDF)
244Nano-LC FTICR Tandem Mass Spectrometry for Top-Down Proteomics: Routine Baseline Unit Mass Resolution of Whole Cell Lysate Proteins up to 72 kDa
Analytical Chemistry, 2012, 84, 2111-2117
6.539Citations (PDF)
245Interrogation of Global Active Site Occupancy of a Fungal Iterative Polyketide Synthase Reveals Strategies for Maintaining Biosynthetic Fidelity15.046Citations (PDF)
246Mechanism-Based Small Molecule Cross-Linkers of HECT E3 Ubiquitin Ligase–Substrate Pairs
Biochemistry, 2012, 51, 8327-8329
2.48Citations (PDF)
247A protease for 'middle-down' proteomics
Nature Methods, 2012, 9, 822-824
24.6113Citations (PDF)
248Evaluation of the Compact High-Field Orbitrap for Top-Down Proteomics of Human Cells
Journal of Proteome Research, 2012, 11, 4308-4314
3.486Citations (PDF)
249A Proteomic Survey of Nonribosomal Peptide and Polyketide Biosynthesis in Actinobacteria3.441Citations (PDF)
250Complexity Generation in Fungal Peptidyl Alkaloid Biosynthesis: Oxidation of Fumiquinazoline A to the Heptacyclic Hemiaminal Fumiquinazoline C by the Flavoenzyme Af12070 from Aspergillus fumigatus
Biochemistry, 2011, 50, 8756-8769
2.463Citations (PDF)
251Proteomics-Based Discovery of Koranimine, a Cyclic Imine Natural Product15.063Citations (PDF)
252Mapping intact protein isoforms in discovery mode using top-down proteomics
Nature, 2011, 480, 254-258
37.9639Citations (PDF)
253Nine Enzymes Are Required for Assembly of the Pacidamycin Group of Peptidyl Nucleoside Antibiotics15.0103Citations (PDF)
254Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo2.152Citations (PDF)
255Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics
ACS Chemical Biology, 2011, 6, 1307-1313
3.789Citations (PDF)
256tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics7.584Citations (PDF)
257The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells
Blood, 2011, 117, 211-220
4.8334Citations (PDF)
258Identification of phosphorylated human peptides by accurate mass measurement alone1.67Citations (PDF)
259A Head-to-Head Comparison of Eneamide and Epoxyamide Inhibitors of Glucosamine-6-Phosphate Synthase from the Dapdiamide Biosynthetic Pathway
Biochemistry, 2011, 50, 3859-3861
2.434Citations (PDF)
260Analysis of Intact Protein Isoforms by Mass Spectrometry
Journal of Biological Chemistry, 2011, 286, 25451-25458
2.292Citations (PDF)
261Directed Evolution of the Nonribosomal Peptide Synthetase AdmK Generates New Andrimid Derivatives In Vivo
Chemistry and Biology, 2011, 18, 601-607
4.7128Citations (PDF)
262MMSET Contributes to Multiple Myeloma Oncogenesis Through Induction of Global Epigenetic Changes and Alteration of the DNA Damage Response,
Blood, 2011, 118, 3475-3475
4.80Citations (PDF)
263Mass Spectrometry Screening Reveals Peptides Modulated Differentially in the Medial Prefrontal Cortex of Rats with Disparate Initial Sensitivity to Cocaine
AAPS Journal, 2010, 12, 443-454
3.125Citations (PDF)
264Efficient readout of posttranslational codes on the 50-residue tail of histone H3 by high-resolution MS/MS
Analytical Biochemistry, 2010, 396, 180-187
2.412Citations (PDF)
265Deciphering the Late Biosynthetic Steps of Antimalarial Compound FR-900098
Chemistry and Biology, 2010, 17, 57-64
4.740Citations (PDF)
266Intact mass detection, interpretation, and visualization to automate Top‐Down proteomics on a large scale
Proteomics, 2010, 10, 3589-3597
3.150Citations (PDF)
267Endogenous Peptide Discovery of the Rat Circadian Clock3.087Citations (PDF)
268Kinetics of Re-establishing H3K79 Methylation Marks in Global Human Chromatin*
Journal of Biological Chemistry, 2010, 285, 32778-32786
2.261Citations (PDF)
269Size-Sorting Combined with Improved Nanocapillary Liquid Chromatography−Mass Spectrometry for Identification of Intact Proteins up to 80 kDa
Analytical Chemistry, 2010, 82, 1234-1244
6.594Citations (PDF)
270The Nonribosomal Peptide Synthetase Enzyme DdaD Tethers Nβ-Fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-Ketoglutarate-Dependent Epoxidation by DdaC during Dapdiamide Antibiotic Biosynthesis15.042Citations (PDF)
271The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput
Molecular BioSystems, 2010, 6, 1532-1539
3.194Citations (PDF)
272Negative regulation of NF‐κB action by Set9‐mediated lysine methylation of the RelA subunit
EMBO Journal, 2009, 28, 1055-1066
7.3212Citations (PDF)
273A proteomics approach to discovering natural products and their biosynthetic pathways
Nature Biotechnology, 2009, 27, 951-956
29.8138Citations (PDF)
274Top-down proteomics reveals novel protein forms expressed in methanosarcina acetivorans2.637Citations (PDF)
275A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome2.694Citations (PDF)
276Global histone profiling by LC–FTMS after inhibition and knockdown of deacetylases in human cells2.622Citations (PDF)
277In Vitro Characterization of a Heterologously Expressed Nonribosomal Peptide Synthetase Involved in Phosphinothricin Tripeptide Biosynthesis
Biochemistry, 2009, 48, 5054-5056
2.418Citations (PDF)
278Distributive and Directional Behavior of Lantibiotic Synthetases Revealed by High-Resolution Tandem Mass Spectrometry15.051Citations (PDF)
279Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval3.462Citations (PDF)
280Accessing natural product biosynthetic processes by mass spectrometry5.832Citations (PDF)
281Cloning, Expression, and Biochemical Characterization of Streptomyces rubellomurinus Genes Required for Biosynthesis of Antimalarial Compound FR900098
Chemistry and Biology, 2008, 15, 765-770
4.7106Citations (PDF)
282Global Amine and Acid Functional Group Modification of Proteins
Analytical Chemistry, 2008, 80, 713-720
6.523Citations (PDF)
283“Proteotyping”:  Population Proteomics of Human Leukocytes Using Top Down Mass Spectrometry
Analytical Chemistry, 2008, 80, 2857-2866
6.561Citations (PDF)
284Interpreting Top-Down Mass Spectra Using Spectral Alignment
Analytical Chemistry, 2008, 80, 2499-2505
6.576Citations (PDF)
285Combinatorial Modification of Human Histone H4 Quantitated by Two-dimensional Liquid Chromatography Coupled with Top Down Mass Spectrometry
Journal of Biological Chemistry, 2008, 283, 14927-14937
2.2171Citations (PDF)
286Gatekeeping versus Promiscuity in the Early Stages of the Andrimid Biosynthetic Assembly Line
ACS Chemical Biology, 2008, 3, 542-554
3.740Citations (PDF)
287Polyunsaturated Fatty-Acid-Like Trans-Enoyl Reductases Utilized in Polyketide Biosynthesis15.059Citations (PDF)
288Neuropeptidomics of the Supraoptic Rat Nucleus
Journal of Proteome Research, 2008, 7, 4992-5003
3.462Citations (PDF)
289Tissue-Specific Expression and Post-Translational Modification of Histone H3 Variants
Journal of Proteome Research, 2008, 7, 4225-4236
3.469Citations (PDF)
290Versatile Online−Offline Engine for Automated Acquisition of High-Resolution Tandem Mass Spectra
Analytical Chemistry, 2008, 80, 8055-8063
6.531Citations (PDF)
291Certain and Progressive Methylation of Histone H4 at Lysine 20 during the Cell Cycle2.5287Citations (PDF)
292Mass spectrometry-based discovery of circadian peptides7.5105Citations (PDF)
293Preferential Dimethylation of Histone H4 Lysine 20 by Suv4-20
Journal of Biological Chemistry, 2008, 283, 12085-12092
2.2124Citations (PDF)
294A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis7.593Citations (PDF)
295A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both α- and β-ketone reduction during chain growth7.546Citations (PDF)
296Using ProSight PTM and Related Tools for Targeted Protein Identification and Characterization with High Mass Accuracy Tandem MS Data3.338Citations (PDF)
297ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry
Nucleic Acids Research, 2007, 35, W701-W706
15.5241Citations (PDF)
298Mild Performic Acid Oxidation Enhances Chromatographic and Top Down Mass Spectrometric Analyses of Histones3.059Citations (PDF)
299Global Assessment of Combinatorial Post-translational Modification of Core Histones in Yeast Using Contemporary Mass Spectrometry
Journal of Biological Chemistry, 2007, 282, 27923-27934
2.279Citations (PDF)
300Characterization of Proteomic and Metabolomic Responses to Dietary Factors and Supplements1,
Journal of Nutrition, 2007, 137, 2787-2793
2.933Citations (PDF)
301The Loading Module of Mycosubtilin:  An Adenylation Domain with Fatty Acid Selectivity15.078Citations (PDF)
302Characterization of the Aminocarboxycyclopropane-Forming Enzyme CmaC†
Biochemistry, 2007, 46, 359-368
2.446Citations (PDF)
303Top-Down Proteomics on a Chromatographic Time Scale Using Linear Ion Trap Fourier Transform Hybrid Mass Spectrometers
Analytical Chemistry, 2007, 79, 7984-7991
6.5120Citations (PDF)
304A Selective Chemical Probe for Coenzyme A‐Requiring Enzymes14.448Citations (PDF)
305Reassignment of the Structure of the Antibiotic A53868 Reveals an Unusual Amino Dehydrophosphonic Acid14.444Citations (PDF)
306A Selective Chemical Probe for Coenzyme A‐Requiring Enzymes
Angewandte Chemie, 2007, 119, 7765-7768
1.47Citations (PDF)
307Reassignment of the Structure of the Antibiotic A53868 Reveals an Unusual Amino Dehydrophosphonic Acid
Angewandte Chemie, 2007, 119, 9247-9250
1.44Citations (PDF)
308Genome-Wide High-Throughput Mining of Natural-Product Biosynthetic Gene Clusters by Phage Display
Chemistry and Biology, 2007, 14, 303-312
4.753Citations (PDF)
309Incorporation of Nonmethyl Branches by Isoprenoid-like Logic: Multiple β-Alkylation Events in the Biosynthesis of Myxovirescin A1
Chemistry and Biology, 2007, 14, 835-846
4.774Citations (PDF)
310Characterization of neurohistone variants and post-translational modifications by electron capture dissociation mass spectrometry1.640Citations (PDF)
311Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide
Nature Chemical Biology, 2007, 3, 480-485
11.8149Citations (PDF)
312Pervasive combinatorial modification of histone H3 in human cells
Nature Methods, 2007, 4, 487-489
24.6229Citations (PDF)
313Protein Assembly Line Components in Prodigiosin Biosynthesis:  Characterization of PigA,G,H,I,J15.068Citations (PDF)
314Dissecting non-ribosomal and polyketide biosynthetic machineries using electrospray ionization Fourier-Transform mass spectrometry10.666Citations (PDF)
315Facile Detection of Acyl and Peptidyl Intermediates on Thiotemplate Carrier Domains via Phosphopantetheinyl Elimination Reactions during Tandem Mass Spectrometry†
Biochemistry, 2006, 45, 12756-12766
2.4173Citations (PDF)
316Probing Intra- versus Interchain Kinetic Preferences of L-Thr Acylation on Dimeric VibF with Mass Spectrometry
Biophysical Journal, 2006, 91, 2609-2619
2.25Citations (PDF)
317Biosynthesis of Pipecolic Acid by RapL, a Lysine Cyclodeaminase Encoded in the Rapamycin Gene Cluster15.0145Citations (PDF)
318Structural Characterization of in Vitro and in Vivo Intermediates on the Loading Module of Microcystin Synthetase
ACS Chemical Biology, 2006, 1, 93-102
3.754Citations (PDF)
319Top-Down Approaches for Measuring Expression Ratios of Intact Yeast Proteins Using Fourier Transform Mass Spectrometry
Analytical Chemistry, 2006, 78, 686-694
6.577Citations (PDF)
320The Dehydratase Activity of Lacticin 481 Synthetase is Highly Processive15.031Citations (PDF)
321Mass Spectrometric Characterization of Human Histone H3:  A Bird's Eye View3.4182Citations (PDF)
322Quantitative Analysis of Modified Proteins and Their Positional Isomers by Tandem Mass Spectrometry:  Human Histone H4
Analytical Chemistry, 2006, 78, 4271-4280
6.5238Citations (PDF)
323Precise Characterization of Human Histones in the H2A Gene Family by Top Down Mass Spectrometry3.4157Citations (PDF)
324Gene-Specific Characterization of Human Histone H2B by Electron Capture Dissociation3.4106Citations (PDF)
325Evolutionary Migration of a Post-Translationally Modified Active-Site Residue in the Proton-Pumping Heme-Copper Oxygen Reductases†
Biochemistry, 2006, 45, 15405-15410
2.467Citations (PDF)
326The Bifunctional Glyceryl Transferase/Phosphatase OzmB Belonging to the HAD Superfamily That Diverts 1,3-Bisphosphoglycerate into Polyketide Biosynthesis15.055Citations (PDF)
327A monovalent streptavidin with a single femtomolar biotin binding site
Nature Methods, 2006, 3, 267-273
24.6363Citations (PDF)
328Heterologous Production of Fosfomycin and Identification of the Minimal Biosynthetic Gene Cluster
Chemistry and Biology, 2006, 13, 1171-1182
4.7125Citations (PDF)
329Investigating Nonribosomal Peptide and Polyketide Biosynthesis by Direct Detection of Intermediates on >70 kDa Polypeptides by Using Fourier-Transform Mass Spectrometry
ChemBioChem, 2006, 7, 904-907
2.621Citations (PDF)
330Identification and characterization of homologues of vertebrate β-thymosin in the marine molluskAplysia californica
Journal of Mass Spectrometry, 2006, 41, 1030-1040
1.725Citations (PDF)
331Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein7.542Citations (PDF)
332Kinetic and Mass Spectrometric Analysis of p300 Histone Acetyltransferase Domain Autoacetylation
Journal of Biological Chemistry, 2006, 281, 40292-40301
2.279Citations (PDF)
333Substrate Specificity of the Adenylation Enzyme SgcC1 Involved in the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027
Journal of Biological Chemistry, 2006, 281, 29633-29640
2.232Citations (PDF)
334Convergence of isoprene and polyketide biosynthetic machinery: Isoprenyl- S -carrier proteins in the pksX pathway of Bacillus subtilis7.5174Citations (PDF)
335Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic7.5237Citations (PDF)
336Top Down Mass Spectrometry of <60-kDa Proteins from Methanosarcina acetivorans Using Quadrupole FTMS with Automated Octopole Collisionally Activated Dissociation3.062Citations (PDF)
337Comprehensive Phosphoprotein Analysis of Linker Histone H1 from Tetrahymena thermophila3.057Citations (PDF)
338Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units7.5129Citations (PDF)
339New and automated MSn approaches for top-down identification of modified proteins2.675Citations (PDF)
340Contemporary mass spectrometry for the direct detection of enzyme intermediates5.822Citations (PDF)
341Parallel interrogation of covalent intermediates in the biosynthesis of gramicidin S using high-resolution mass spectrometry
Protein Science, 2005, 14, 2702-2712
5.922Citations (PDF)
342Staphylococcus aureusSortase Transpeptidase SrtA:  Insight into the Kinetic Mechanism and Evidence for a Reverse Protonation Catalytic Mechanism†
Biochemistry, 2005, 44, 11188-11200
2.4141Citations (PDF)
343Lacticin 481 Synthetase Phosphorylates its Substrate during Lantibiotic Production15.0130Citations (PDF)
344Detection and localization of protein modifications by high resolution tandem mass spectrometry
Mass Spectrometry Reviews, 2005, 24, 126-134
6.8130Citations (PDF)
345Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis7.5176Citations (PDF)
346Precise and Parallel Characterization of Coding Polymorphisms, Alternative Splicing, and Modifications in Human Proteins by Mass Spectrometry3.097Citations (PDF)
347Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase7.5422Citations (PDF)
348Characterization of a New Tailoring Domain in Polyketide Biogenesis:  The Amine Transferase Domain of MycA in the Mycosubtilin Gene Cluster15.061Citations (PDF)
349Elucidating the Substrate Specificity and Condensation Domain Activity of FkbP, the FK520 Pipecolate-Incorporating Enzyme
Biochemistry, 2005, 44, 5993-6002
2.463Citations (PDF)
350Monitoring Multiple Active Sites on Thiotemplate Enzymes in Parallel:  A Molecular Movie of Yersiniabactin Bioassembly15.010Citations (PDF)
351Characterization of the Formation of the Pyrrole Moiety during Clorobiocin and Coumermycin A1Biosynthesis†
Biochemistry, 2005, 44, 2770-2780
2.483Citations (PDF)
352Biosynthesis of the β-Amino Acid Moiety of the Enediyne Antitumor Antibiotic C-1027 Featuring β-Amino Acyl-S-carrier Protein Intermediates15.050Citations (PDF)
353Chemoenzymatic Approaches for Streamlined Detection of Active Site Modifications on Thiotemplate Assembly Lines Using Mass Spectrometry†
Biochemistry, 2005, 44, 14159-14169
2.49Citations (PDF)
354Targeted analysis and discovery of posttranslational modifications in proteins from methanogenic archaea by top-down MS7.594Citations (PDF)
355ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry
Nucleic Acids Research, 2004, 32, W340-W345
15.5189Citations (PDF)
356Strategies for automating top-down protein analysis with Q-FTICR MS1.620Citations (PDF)
357Construction of a hybrid quadrupole/fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa2.6109Citations (PDF)
358Mass Spectrometric Interrogation of Thioester-Bound Intermediates in the Initial Stages of Epothilone Biosynthesis
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359Role of the Active Site Cysteine of DpgA, a Bacterial Type III Polyketide Synthase
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362Molecular-Level Description of Proteins fromSaccharomyces cerevisiaeUsing Quadrupole FT Hybrid Mass Spectrometry for Top Down Proteomics
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363Shotgun Annotation of Histone Modifications:  A New Approach for Streamlined Characterization of Proteins by Top Down Mass Spectrometry15.0153Citations (PDF)
364Fourier-transform mass spectrometry for detection of thioester-bound intermediates in unfractionated proteolytic mixtures of 80 and 191 kDa portions of Bacitracin A synthetase
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365Web and Database Software for Identification of Intact Proteins Using “Top Down” Mass Spectrometry
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366Site-Specific Observation of Acyl Intermediate Processing in Thiotemplate Biosynthesis by Fourier Transform Mass Spectrometry:  The Polyketide Module of Yersiniabactin Synthetase
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367Facile synthesis of site-specifically acetylated and methylated histone proteins: Reagents for evaluation of the histone code hypothesis7.5112Citations (PDF)
368Processing Complex Mixtures of Intact Proteins for Direct Analysis by Mass Spectrometry
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369Fourier-transform mass spectrometry for automated fragmentation and identification of 5-20 kDa proteins in mixtures
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371Toward efficient analysis of <70 kDa proteins with 100% sequence coverage
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372Informatics and multiplexing of intact protein identification in bacteria and the archaea
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373From primary structure to function: biological insights from large-molecule mass spectra
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374Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations
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375Electron capture versus energetic dissociation of protein ions1.676Citations (PDF)
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377In vivo processing and antibiotic activity of microcin B17 analogs with varying ring content and altered bisheterocyclic sites
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378Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization
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379Top Down versus Bottom Up Protein Characterization by Tandem High-Resolution Mass Spectrometry15.0564Citations (PDF)
380Posttranslational Heterocyclization of Cysteine and Serine Residues in the Antibiotic Microcin B17:  Distributivity and Directionality†
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381Cofactor Requirements and Reconstitution Of Microcin B17 Synthetase:  A Multienzyme Complex that Catalyzes the Formation of Oxazoles and Thiazoles in the Antibiotic Microcin B17†
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382Localization of Labile Posttranslational Modifications by Electron Capture Dissociation:  The Case of γ-Carboxyglutamic Acid
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383Gaseous Conformational Structures of Cytochromec15.0256Citations (PDF)
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386Two-dimensional mass spectrometry of biomolecules at the subfemtomole level5.838Citations (PDF)
387Efficient sequence analysis of the six gene products (7‐74 kDA) from the escherichia coli thiamin biosynthetic operon by tandem high‐resolution mass spectrometry
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395Mechanistic Studies on Thiaminase I
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398Direct Sequence Data from Heterogeneous Creatine Kinase (43 kDa) by High-Resolution Tandem Mass Spectrometry
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399Attomole-Sensitivity Electrospray Source for Large-Molecule Mass Spectrometry
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400Rapid Sequencing of Oligonucleotides by High-Resolution Mass Spectrometry15.0170Citations (PDF)
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402Bone protein “extractomics”: comparing the efficiency of bone protein extractions ofGallus gallusin tandem mass spectrometry, with an eye towards paleoproteomics
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404Target Identification of a Class of Pyrazolone Protein Aggregation Inhibitor Therapeutics for Amyotrophic Lateral Sclerosis
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406Proteoform profiling of endogenous single cells from rat hippocampus at scale
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407Next-generation protein sequencing and individual ion mass spectrometry enable complementary analysis of interleukin-63.43Citations (PDF)
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411SPAP: Soluble Human Plasma Proteoform Analysis via Acetonitrile Precipitation and Top-Down Mass Spectrometry2.62Citations (PDF)
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413Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry
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