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202 papers • 49,579 citations • Sorted by year • Download PDF (PDF by citations)
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1Differential specificity of <scp>SARS‐CoV</scp>‐2 main protease variants on peptide versus protein‐based substrates
FEBS Journal, 2024, 291, 61-69
5.50Citations (PDF)
2Evolution of Caspases and the Invention of Pyroptosis4.53Citations (PDF)
3Cell organelles are retained inside pyroptotic corpses during inflammatory cell death
Bioscience Reports, 2023, 43,
3.91Citations (PDF)
4Caspase mechanisms in the regulation of inflammation9.318Citations (PDF)
5Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold2.36Citations (PDF)
6Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel Lindau syndrome.3.91Citations (PDF)
7Engineering caspase 7 as an affinity reagent to capture proteolytic products
FEBS Journal, 2021, 288, 1259-1270
5.50Citations (PDF)
8Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7
Biochemical Journal, 2021, 478, 2233-2245
3.96Citations (PDF)
9Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections
Cell Reports, 2021, 36, 109614
6.423Citations (PDF)
10NETosis occurs independently of neutrophil serine proteases
Journal of Biological Chemistry, 2020, 295, 17624-17631
2.325Citations (PDF)
11Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes15.729Citations (PDF)
12Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11
Journal of Biological Chemistry, 2020, 295, 11292-11302
2.337Citations (PDF)
13Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion14.126Citations (PDF)
14Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe
Journal of Medicinal Chemistry, 2020, 63, 3359-3369
6.921Citations (PDF)
15Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
Molecular Cell, 2020, 77, 927-929
14.265Citations (PDF)
16Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes
Journal of Biological Chemistry, 2020, 295, 9567-9582
2.328Citations (PDF)
17Design, synthesis, and <i>in vitro</i> evaluation of aza-peptide aldehydes and ketones as novel and selective protease inhibitors5.38Citations (PDF)
18Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy7.737Citations (PDF)
19Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody
Journal of Biological Chemistry, 2020, 295, 2464-2472
2.314Citations (PDF)
20The Proteasome as a Drug Target in the Metazoan Pathogen, <i>Schistosoma mansoni</i>
ACS Infectious Diseases, 2019, 5, 1802-1812
3.828Citations (PDF)
21Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples
Chemical Science, 2019, 10, 8461-8477
7.553Citations (PDF)
22Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe
Nanoscale, 2019, 11, 742-751
5.15Citations (PDF)
23The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1β Release
Journal of Immunology, 2019, 203, 736-748
0.699Citations (PDF)
24Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation
Cell Reports, 2019, 27, 3646-3656.e5
6.4185Citations (PDF)
25Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells
Cell Death and Differentiation, 2019, 26, 2695-2709
13.724Citations (PDF)
26Exploring the prime site in caspases as a novel chemical strategy for understanding the mechanisms of cell death: a proof of concept study on necroptosis in cancer cells13.78Citations (PDF)
27Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide
Nature Microbiology, 2019, 5, 354-367
12.834Citations (PDF)
28Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes
Chemical Science, 2018, 9, 2113-2129
7.561Citations (PDF)
29Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1
Journal of Biological Chemistry, 2018, 293, 7058-7067
2.380Citations (PDF)
30A primer on caspase mechanisms5.4122Citations (PDF)
31Protease Specificity: Towards In Vivo Imaging Applications and Biomarker Discovery8.151Citations (PDF)
32Caspase selective reagents for diagnosing apoptotic mechanisms13.740Citations (PDF)
33Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families3.753Citations (PDF)
34Differing Requirements for MALT1 Function in Peripheral B Cell Survival and Differentiation
Journal of Immunology, 2017, 198, 1066-1080
0.610Citations (PDF)
35Toolbox of Fluorescent Probes for Parallel Imaging Reveals Uneven Location of Serine Proteases in Neutrophils15.782Citations (PDF)
36Apoptosis Activation in Human Lung Cancer Cell Lines by a Novel Synthetic Peptide Derived from Conus californicus Venom
Toxins, 2016, 8, 38
3.923Citations (PDF)
37Protease signaling in animal and plant‐regulated cell death
FEBS Journal, 2016, 283, 2577-2598
5.580Citations (PDF)
38Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes
Cell Chemical Biology, 2016, 23, 1023-1035
6.443Citations (PDF)
39Response to Comment on “SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML”5.50Citations (PDF)
40The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia13.1146Citations (PDF)
41Regulation of Histone Acetylation by Autophagy in Parkinson Disease
Journal of Biological Chemistry, 2016, 291, 3531-3540
2.3129Citations (PDF)
42The Paracaspase MALT1
Biochimie, 2016, 122, 324-338
3.036Citations (PDF)
43Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4
PLoS ONE, 2015, 10, e0132818
2.548Citations (PDF)
44SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML5.517Citations (PDF)
45Probes to Monitor Activity of the Paracaspase MALT1
Chemistry and Biology, 2015, 22, 139-147
5.323Citations (PDF)
46Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature, 2015, 526, 666-671
40.12,693Citations (PDF)
47Biochemical Characterization and Substrate Specificity of Autophagin-2 from the Parasite Trypanosoma cruzi
Journal of Biological Chemistry, 2015, 290, 28231-28244
2.37Citations (PDF)
48Small Molecule Active Site Directed Tools for Studying Human Caspases
Chemical Reviews, 2015, 115, 12546-12629
54.667Citations (PDF)
49Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.2.31Citations (PDF)
50Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation
Journal of Biological Chemistry, 2014, 289, 15544-15553
2.313Citations (PDF)
51Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling7.7145Citations (PDF)
52A remarkable activity of human leukotriene A4 hydrolase (LTA4H) toward unnatural amino acids
Amino Acids, 2014, 46, 1313-1320
2.319Citations (PDF)
53Regulated Cell Death: Signaling and Mechanisms10.1225Citations (PDF)
54Caspase Enzymology and Activation Mechanisms
Methods in Enzymology, 2014, , 161-178
1.025Citations (PDF)
55Functions of caspase 8: The identified and the mysterious
Seminars in Immunology, 2014, 26, 246-252
6.5109Citations (PDF)
56Caspase Cleavage Sites in the Human Proteome: CaspDB, a Database of Predicted Substrates
PLoS ONE, 2014, 9, e110539
2.556Citations (PDF)
57Expedient Synthesis of Highly Potent Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Unique Selectivity for ML-IAP
ACS Chemical Biology, 2013, 8, 725-732
3.930Citations (PDF)
58Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington’s Disease Models
Chemistry and Biology, 2013, 20, 742
5.30Citations (PDF)
59Caspase Substrates and Inhibitors7.4152Citations (PDF)
60Cathepsin G
2013, , 2661-2666
3Citations (PDF)
61Cathepsin D Primes Caspase-8 Activation by Multiple Intra-chain Proteolysis
Journal of Biological Chemistry, 2012, 287, 21142-21151
2.345Citations (PDF)
62Mitochondrial pathway of apoptosis is ancestral in metazoans7.795Citations (PDF)
63Activity, Specificity, and Probe Design for the Smallpox Virus Protease K7L
Journal of Biological Chemistry, 2012, 287, 39470-39479
2.314Citations (PDF)
64X-ray Crystal Structure and Specificity of the Plasmodium falciparum Malaria Aminopeptidase PfM18AAP
Journal of Molecular Biology, 2012, 422, 495-507
4.234Citations (PDF)
65S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors
Biochimie, 2012, 94, 704-710
3.019Citations (PDF)
66Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 2012, 8, 445-544
13.82,928Citations (PDF)
67An Optimized Activity-Based Probe for the Study of Caspase-6 Activation
Chemistry and Biology, 2012, 19, 340-352
5.345Citations (PDF)
68Glycine Fluoromethylketones as SENP‐Specific Activity Based Probes
ChemBioChem, 2012, 13, 80-84
2.729Citations (PDF)
69Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum
PLoS ONE, 2012, 7, e31938
2.565Citations (PDF)
70FLIPL induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
Biochemical Journal, 2011, 433, 447-457
3.9189Citations (PDF)
71SnapShot: Caspases
Cell, 2011, 147, 476-476.e1
35.148Citations (PDF)
72RIPK-Dependent Necrosis and Its Regulation by Caspases: A Mystery in Five Acts
Molecular Cell, 2011, 44, 9-16
14.2139Citations (PDF)
73Human Caspases – Apoptosis and Inflammation Signaling Proteases
2011, , 1-10
0Citations (PDF)
74Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis
Nature, 2011, 471, 363-367
40.11,063Citations (PDF)
75Functional Characterization of a SUMO Deconjugating Protease of Plasmodium falciparum Using Newly Identified Small Molecule Inhibitors
Chemistry and Biology, 2011, 18, 711-721
5.337Citations (PDF)
76Development of Small Molecule Inhibitors and Probes of Human SUMO Deconjugating Proteases
Chemistry and Biology, 2011, 18, 722-732
5.357Citations (PDF)
77The Dynamics and Mechanism of SUMO Chain Deconjugation by SUMO-specific Proteases
Journal of Biological Chemistry, 2011, 286, 10238-10247
2.360Citations (PDF)
78Intranasal Delivery of Caspase-9 Inhibitor Reduces Caspase-6-Dependent Axon/Neuron Loss and Improves Neurological Function after Stroke
Journal of Neuroscience, 2011, 31, 8894-8904
3.781Citations (PDF)
79Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity7.7109Citations (PDF)
80Urm1 couples sulfur transfer to ubiquitin-like protein function in oxidative stress7.720Citations (PDF)
81Targeting activated integrin αvβ3 with patient-derived antibodies impacts late-stage multiorgan metastasis2.912Citations (PDF)
82Divide and die another day4.20Citations (PDF)
83Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models
Chemistry and Biology, 2010, 17, 1189-1200
5.348Citations (PDF)
84Identification of very potent inhibitor of human aminopeptidase N (CD13)2.124Citations (PDF)
85Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
Nature, 2010, 467, 863-867
40.1890Citations (PDF)
86Emerging principles in protease-based drug discovery39.3460Citations (PDF)
87Vaccinia Virus Protein F1L Is a Caspase-9 Inhibitor
Journal of Biological Chemistry, 2010, 285, 5569-5580
2.340Citations (PDF)
88Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation
Journal of Biological Chemistry, 2010, 285, 16632-16642
2.3166Citations (PDF)
89Aminopeptidase Fingerprints, an Integrated Approach for Identification of Good Substrates and Optimal Inhibitors
Journal of Biological Chemistry, 2010, 285, 3310-3318
2.392Citations (PDF)
90Regulation of the Apaf-1–caspase-9 apoptosome
Journal of Cell Science, 2010, 123, 3209-3214
3.2340Citations (PDF)
91Transnitrosylation of XIAP Regulates Caspase-Dependent Neuronal Cell Death
Molecular Cell, 2010, 39, 184-195
14.2163Citations (PDF)
92Streptolysin O Promotes Group A Streptococcus Immune Evasion by Accelerated Macrophage Apoptosis2.3139Citations (PDF)
93Structure of the Fas/FADD complex: A conditional death domain complex mediating signaling by receptor clustering
Cell Cycle, 2009, 8, 2723-2727
3.230Citations (PDF)
94Nicotinamide Rescues Human Embryonic Stem Cell-Derived Neuroectoderm from Parthanatic Cell Death
Stem Cells, 2009, 27, 1772-1781
3.332Citations (PDF)
95Structural and kinetic determinants of protease substrates6.4109Citations (PDF)
96Protection from Isopeptidase-Mediated Deconjugation Regulates Paralog-Selective Sumoylation of RanGAP1
Molecular Cell, 2009, 33, 570-580
14.257Citations (PDF)
97Human Caspases: Activation, Specificity, and Regulation
Journal of Biological Chemistry, 2009, 284, 21777-21781
2.3571Citations (PDF)
98Proteolytic needles in the cellular haystack
Nature Chemical Biology, 2008, 4, 651-652
7.34Citations (PDF)
99Caspase Mechanisms0.0186Citations (PDF)
100Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues
Journal of Biological Chemistry, 2008, 283, 19140-19150
2.3324Citations (PDF)
101Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function
Journal of Biological Chemistry, 2008, 283, 19499-19510
2.341Citations (PDF)
102Chapter 21 Caspase Assays: Identifying Caspase Activity and Substrates In Vitro and In Vivo
Methods in Enzymology, 2008, , 351-367
1.029Citations (PDF)
103The Fas–FADD death domain complex structure unravels signalling by receptor clustering
Nature, 2008, 457, 1019-1022
40.1312Citations (PDF)
104Carboxyl-terminal Proteolytic Processing of CUX1 by a Caspase Enables Transcriptional Activation in Proliferating Cells
Journal of Biological Chemistry, 2007, 282, 30216-30226
2.339Citations (PDF)
105Small Ubiquitin-related Modifier (SUMO)-specific Proteases
Journal of Biological Chemistry, 2007, 282, 26217-26224
2.3130Citations (PDF)
106Identification of Proteolytic Cleavage Sites by Quantitative Proteomics
Journal of Proteome Research, 2007, 6, 2850-2858
3.773Citations (PDF)
107The apoptosome: signalling platform of cell death31.4871Citations (PDF)
108Caspase Inhibition, Specifically
Structure, 2007, 15, 513-514
3.910Citations (PDF)
109Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and -10
Journal of Medicinal Chemistry, 2006, 49, 5728-5749
6.960Citations (PDF)
110The Apoptosome Activates Caspase-9 by Dimerization
Molecular Cell, 2006, 22, 269-275
14.2233Citations (PDF)
111Engineered Hybrid Dimers: Tracking the Activation Pathway of Caspase-7
Molecular Cell, 2006, 23, 523-533
14.234Citations (PDF)
112Identification of Early Intermediates of Caspase Activation Using Selective Inhibitors and Activity-Based Probes
Molecular Cell, 2006, 23, 509-521
14.2108Citations (PDF)
113Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
EMBO Reports, 2006, 7, 988-994
5.3681Citations (PDF)
114The Human Anti-apoptotic Proteins cIAP1 and cIAP2 Bind but Do Not Inhibit Caspases
Journal of Biological Chemistry, 2006, 281, 3254-3260
2.3302Citations (PDF)
115Cytokine Response Modifier A Inhibition of Initiator Caspases Results in Covalent Complex Formation and Dissociation of the Caspase Tetramer
Journal of Biological Chemistry, 2006, 281, 38781-38790
2.326Citations (PDF)
116Activity-based probes that target diverse cysteine protease families
Nature Chemical Biology, 2005, 1, 33-38
7.3303Citations (PDF)
117XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs
EMBO Journal, 2005, 24, 645-655
7.4340Citations (PDF)
118Yersinia Phosphatase Induces Mitochondrially Dependent Apoptosis of T Cells
Journal of Biological Chemistry, 2005, 280, 10388-10394
2.325Citations (PDF)
119Lack of involvement of strand s1′A of the viral serpin CrmA in anti-apoptotic or caspase-inhibitory functions2.72Citations (PDF)
120Selective Disruption of Lysosomes in HeLa Cells Triggers Apoptosis Mediated by Cleavage of Bid by Multiple Papain-like Lysosomal Cathepsins
Journal of Biological Chemistry, 2004, 279, 3578-3587
2.3398Citations (PDF)
121Glycosylation Broadens the Substrate Profile of Membrane Type 1 Matrix Metalloproteinase
Journal of Biological Chemistry, 2004, 279, 8278-8289
2.376Citations (PDF)
122An IAP-IAP Complex Inhibits Apoptosis
Journal of Biological Chemistry, 2004, 279, 34087-34090
2.3308Citations (PDF)
123Neutralization of Smac/Diablo by Inhibitors of Apoptosis (IAPs)
Journal of Biological Chemistry, 2004, 279, 51082-51090
2.394Citations (PDF)
124Caspase activation – stepping on the gas or releasing the brakes? Lessons from humans and flies
Oncogene, 2004, 23, 2774-2784
6.6207Citations (PDF)
125Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
Cancer Cell, 2004, 5, 25-35
33.4375Citations (PDF)
126The protein structures that shape caspase activity, specificity, activation and inhibition
Biochemical Journal, 2004, 384, 201-232
3.9709Citations (PDF)
127Aza-Peptide Michael Acceptors:  A New Class of Inhibitors Specific for Caspases and Other Clan CD Cysteine Proteases
Journal of Medicinal Chemistry, 2004, 47, 1889-1892
6.975Citations (PDF)
128Design, Synthesis, and Evaluation of Aza-Peptide Epoxides as Selective and Potent Inhibitors of Caspases-1, -3, -6, and -8
Journal of Medicinal Chemistry, 2004, 47, 1553-1574
6.953Citations (PDF)
129Mechanisms of caspase activation4.21,096Citations (PDF)
130A Unified Model for Apical Caspase Activation
Molecular Cell, 2003, 11, 529-541
14.2789Citations (PDF)
131Comparative Analysis of Apoptosis and Inflammation Genes of Mice and Humans
Genome Research, 2003, 13, 1376-1388
4.6100Citations (PDF)
132XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma–derived B Cells8.1117Citations (PDF)
133Human Caspase-7 Activity and Regulation by Its N-terminal Peptide
Journal of Biological Chemistry, 2003, 278, 34042-34050
2.395Citations (PDF)
134Sequential Autolytic Processing Activates the Zymogen of Arg-gingipain
Journal of Biological Chemistry, 2003, 278, 10458-10464
2.352Citations (PDF)
135Ionomycin-activated Calpain Triggers Apoptosis
Journal of Biological Chemistry, 2002, 277, 27217-27226
2.3177Citations (PDF)
136Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis7.7127Citations (PDF)
137Aza-Peptide Epoxides:  A New Class of Inhibitors Selective for Clan CD Cysteine Proteases
Journal of Medicinal Chemistry, 2002, 45, 4958-4960
6.959Citations (PDF)
138Caspases:  Keys in the Ignition of Cell Death
Chemical Reviews, 2002, 102, 4489-4500
54.6268Citations (PDF)
139Expression, Purification, and Characterization of Caspases3.531Citations (PDF)
140Regulating Cysteine Protease Activity: Essential Role of Protease Inhibitors As Guardians and Regulators
Current Pharmaceutical Design, 2002, 8, 1623-1637
2.3216Citations (PDF)
141Reprieval from execution: the molecular basis of caspase inhibition8.1152Citations (PDF)
142Caspases on the brain3.3102Citations (PDF)
143Caspases: opening the boxes and interpreting the arrows13.7243Citations (PDF)
144IAP proteins: blocking the road to death's door31.41,529Citations (PDF)
145Direct Cleavage of AMPA Receptor Subunit GluR1 and Suppression of AMPA Currents by Caspase-3
NeuroMolecular Medicine, 2002, 1, 69-80
3.757Citations (PDF)
146Caspases and apoptosis
Essays in Biochemistry, 2002, 38, 9-19
5.3155Citations (PDF)
147Structural Basis for the Inhibition of Caspase-3 by XIAP
Cell, 2001, 104, 791-800
35.1662Citations (PDF)
148The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins
Journal of Biological Chemistry, 2001, 276, 33293-33296
2.31,027Citations (PDF)
149Caspase-3-mediated Processing of Poly(ADP-ribose) Glycohydrolase during Apoptosis
Journal of Biological Chemistry, 2001, 276, 2935-2942
2.3106Citations (PDF)
150TRAF1 Is a Substrate of Caspases Activated during Tumor Necrosis Factor Receptor-α-induced Apoptosis
Journal of Biological Chemistry, 2001, 276, 8087-8093
2.359Citations (PDF)
151Lysosomal Protease Pathways to Apoptosis
Journal of Biological Chemistry, 2001, 276, 3149-3157
2.3561Citations (PDF)
152A lysosomal protease enters the death scene9.157Citations (PDF)
153Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
Biochemical Journal, 2000, 350, 563-568
3.9272Citations (PDF)
154Viral Caspase Inhibitors CrmA and p35
Methods in Enzymology, 2000, , 143-154
1.028Citations (PDF)
155A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
Nature Medicine, 2000, 6, 397-404
25.6365Citations (PDF)
156ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
Current Biology, 2000, 10, 1359-1366
3.9357Citations (PDF)
157Crystal structure of the apoptotic suppressor CrmA in its cleaved form
Structure, 2000, 8, 789-797
3.955Citations (PDF)
158Caspase Assays
Methods in Enzymology, 2000, , 91-100
1.087Citations (PDF)
159Caspase-9 Can Be Activated without Proteolytic Processing
Journal of Biological Chemistry, 1999, 274, 8359-8362
2.3414Citations (PDF)
160Cleavage of Atrophin-1 at Caspase Site Aspartic Acid 109 Modulates Cytotoxicity
Journal of Biological Chemistry, 1999, 274, 8730-8736
2.394Citations (PDF)
161Cleavage of Automodified Poly(ADP-ribose) Polymerase during Apoptosis
Journal of Biological Chemistry, 1999, 274, 28379-28384
2.3393Citations (PDF)
162Kennedy's Disease
Journal of Neurochemistry, 1999, 72, 185-195
4.0192Citations (PDF)
163Title is missing!3.4143Citations (PDF)
164Caspase 8: igniting the death machine
Structure, 1999, 7, R225-R229
3.935Citations (PDF)
165Solution Structure of BID, an Intracellular Amplifier of Apoptotic Signaling
Cell, 1999, 96, 615-624
35.1431Citations (PDF)
166Regulation of Cell Death Protease Caspase-9 by Phosphorylation
Science, 1998, 282, 1318-1321
38.22,545Citations (PDF)
167The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis
Nature, 1998, 395, 801-804
40.1368Citations (PDF)
168Anti-apoptotic oncogenes prevent caspase-dependent and independent commitment for cell death13.7163Citations (PDF)
169Investigation of glucocorticoid-induced apoptotic pathway: Processing of Caspase-6 but not Caspase-3
Cell Death and Differentiation, 1998, 5, 1034-1041
13.749Citations (PDF)
170Granzyme Release and Caspase Activation in Activated Human T-Lymphocytes
Journal of Biological Chemistry, 1998, 273, 6916-6920
2.3114Citations (PDF)
171Caspase-14 Is a Novel Developmentally Regulated Protease
Journal of Biological Chemistry, 1998, 273, 29648-29653
2.3119Citations (PDF)
172A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases
Journal of Biological Chemistry, 1998, 273, 7787-7790
2.3497Citations (PDF)
173Granzyme B Mimics Apical Caspases
Journal of Biological Chemistry, 1998, 273, 34278-34283
2.3136Citations (PDF)
174Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract
Journal of Biological Chemistry, 1998, 273, 9158-9167
2.3475Citations (PDF)
175Pro-caspase-3 Is a Major Physiologic Target of Caspase-8
Journal of Biological Chemistry, 1998, 273, 27084-27090
2.3626Citations (PDF)
176An Induced Proximity Model for Caspase-8 Activation
Journal of Biological Chemistry, 1998, 273, 2926-2930
2.3843Citations (PDF)
177Target Protease Specificity of the Viral Serpin CrmA
Journal of Biological Chemistry, 1997, 272, 7797-7800
2.3478Citations (PDF)
178Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis
Journal of Cell Biology, 1997, 138, 1379-1394
4.8536Citations (PDF)
179Zinc Is a Potent Inhibitor of the Apoptotic Protease, Caspase-3
Journal of Biological Chemistry, 1997, 272, 18530-18533
2.3416Citations (PDF)
180FLICE Induced Apoptosis in a Cell-free System
Journal of Biological Chemistry, 1997, 272, 2952-2956
2.3306Citations (PDF)
181The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases
Cell, 1997, 90, 315-323
35.1466Citations (PDF)
182Caspases: Intracellular Signaling by Proteolysis
Cell, 1997, 91, 443-446
35.11,927Citations (PDF)
183Biochemical Characteristics of Caspases-3, -6, -7, and -8
Journal of Biological Chemistry, 1997, 272, 25719-25723
2.3462Citations (PDF)
184X-linked IAP is a direct inhibitor of cell-death proteases
Nature, 1997, 388, 300-304
40.11,701Citations (PDF)
185Granzyme B/Perforin-Mediated Apoptosis of Jurkat Cells Results in Cleavage of Poly(ADP-ribose) Polymerase to the 89-kDa Apoptotic Fragment and Less Abundant 64-kDa Fragment2.197Citations (PDF)
186Human ICE/CED-3 Protease Nomenclature
Cell, 1996, 87, 171
35.11,966Citations (PDF)
187Interaction of subtilisins with serpins
Protein Science, 1996, 5, 874-882
5.922Citations (PDF)
188Serpin α<sub>1</sub>proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy
Protein Science, 1996, 5, 2226-2235
5.923Citations (PDF)
189Molecular Ordering of Apoptotic Mammalian CED-3/ICE-like Proteases
Journal of Biological Chemistry, 1996, 271, 20977-20980
2.3174Citations (PDF)
190α1-Microglobulin Destroys the Proteinase Inhibitory Activity of α1-Inhibitor-3 by Complex Formation
Journal of Biological Chemistry, 1995, 270, 4478-4483
2.310Citations (PDF)
191Granzyme B Is Inhibited by the Cowpox Virus Serpin Cytokine Response Modifier A
Journal of Biological Chemistry, 1995, 270, 10377-10379
2.3194Citations (PDF)
192Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
Cell, 1995, 81, 801-809
35.12,259Citations (PDF)
193[7] α-Macroglobulins: Detection and characterization
Methods in Enzymology, 1993, , 121-141
1.046Citations (PDF)
194Expression of a functional α-macroglobulin receptor binding domain inEscherichia coli
FEBS Letters, 1992, 313, 198-202
2.820Citations (PDF)
195Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
Cell, 1992, 69, 597-604
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196Substrate specificities and activation mechanisms of matrix metalloproteinases4.2162Citations (PDF)
197Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts
FEBS Journal, 1990, 194, 721-730
0.3369Citations (PDF)
198[21] Human kininogens
Methods in Enzymology, 1988, , 240-256
1.036Citations (PDF)
199cDNA encoding a human homolog of yeast ubiquitin 1
Nucleic Acids Research, 1987, 15, 5485-5485
16.237Citations (PDF)
200Rapid isolation of human kininogens
Thrombosis Research, 1987, 48, 187-193
2.437Citations (PDF)
201INTERACTION OF ?2-MACROGLOBULIN WITH NEUTROPHIL AND PLASMA PROTEINASES4.526Citations (PDF)
202Comparison of the Structure and Aspects of the Proteinase-Binding Properties of Cystic Fibrotic α2-Macroglobulin with Normal α2-Macroglobulin
Pediatric Research, 1982, 16, 416-423
2.18Citations (PDF)