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653 PR articles • 72,090 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Melflufen in relapsed/refractory multiple myeloma refractory to prior alkylators: A subgroup analysis from the <scp>OCEAN study</scp>1.92Citations (PDF)
2Health‐related quality of life in transplant‐eligible patients with newly diagnosed multiple myeloma treated with daratumumab, lenalidomide, bortezomib, and dexamethasone: Patient‐reported outcomes from <scp>GRIFFIN</scp>
American Journal of Hematology, 2024, 99, 1257-1268
6.13Citations (PDF)
3Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk7.921Citations (PDF)
4Impact of prior treatment on selinexor, bortezomib, dexamethasone outcomes in patients with relapsed/refractory multiple myeloma: Extended follow‐up subgroup analysis of the <scp>BOSTON</scp> trial1.910Citations (PDF)
5Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN7.927Citations (PDF)
6An open‐label, first‐in‐human, single agent, dose escalation study for the evaluation of safety and efficacy of <scp>SAR442085</scp> in patients with relapsed or refractory multiple myeloma1.91Citations (PDF)
7Multiple myeloma refractory to lenalidomide: A systematic literature review of trials and real‐world evidence
British Journal of Haematology, 2024, 205, 780-797
2.411Citations (PDF)
8Targeting Ikaros and Aiolos: reviewing novel protein degraders for the treatment of multiple myeloma, with a focus on iberdomide and mezigdomide
Expert Review of Hematology, 2024, 17, 445-465
2.09Citations (PDF)
9Progression-free survival as a surrogate endpoint in myeloma clinical trials: an evolving paradigm7.912Citations (PDF)
10Stem Cell Mobilization Yields with Daratumumab- and Lenalidomide-Containing Quadruplet Induction Therapy in Newly Diagnosed Multiple Myeloma: Findings from the MASTER and GRIFFIN Trials
Transplantation and Cellular Therapy, 2023, 29, 174.e1-174.e10
2.049Citations (PDF)
11Mutations in the alternative complement pathway in multiple myeloma patients with carfilzomib-induced thrombotic microangiopathy7.916Citations (PDF)
12Selinexor: Targeting a novel pathway in multiple myeloma
EJHaem, 2023, 4, 792-810
1.721Citations (PDF)
13Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT)
Bone Marrow Transplantation, 2023, 58, 749-754
3.376Citations (PDF)
14Late versus early response and depth of response are associated with improved outcomes in patients with newly diagnosed multiple myeloma enrolled in the TOURMALINE‐MM2 trial
EJHaem, 2023, ,
1.71Citations (PDF)
15A safety review of recently approved and emerging drugs for patients with relapsed or refractory multiple myeloma
Expert Opinion on Drug Safety, 2023, 22, 1049-1071
2.75Citations (PDF)
16Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes
Shock, 2022, 57, 95-105
2.452Citations (PDF)
17Pomalidomide, bortezomib, and dexamethasone at first relapse in lenalidomide‐pretreated myeloma: A subanalysis of OPTIMISMM by clinical characteristics1.99Citations (PDF)
18Patient‐reported outcomes in relapsed/refractory multiple myeloma treated with melflufen plus dexamethasone: analyses from the Phase II HORIZON study
British Journal of Haematology, 2022, 196, 639-648
2.410Citations (PDF)
19Defibrotide: real-world management of veno-occlusive disease/sinusoidal obstructive syndrome after stem cell transplant
Blood Advances, 2022, 6, 181-188
5.130Citations (PDF)
20Cell-free DNA for the detection of emerging treatment failure in relapsed/ refractory multiple myeloma
Leukemia, 2022, 36, 1078-1087
10.426Citations (PDF)
21The emerging importance and evolving understanding of clonal hematopoiesis in multiple myeloma
Seminars in Oncology, 2022, 49, 19-26
1.96Citations (PDF)
22DUPLICATE: Treatment Options for Patients With Heavily Pretreated Relapsed and Refractory Multiple Myeloma1.00Citations (PDF)
23Treatment Options for Patients With Heavily Pretreated Relapsed and Refractory Multiple Myeloma1.038Citations (PDF)
24Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN): a randomised, head-to-head, open-label, phase 3 study
Lancet Haematology,the, 2022, 9, e98-e110
9.260Citations (PDF)
25Phase 2 studies of lenalidomide, subcutaneous bortezomib, and dexamethasone as induction therapy in patients with newly diagnosed multiple myeloma6.14Citations (PDF)
26Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): follow-up analysis of a randomised, phase 3 study
Lancet Oncology, The, 2022, 23, 416-427
26.0109Citations (PDF)
27An overview of treatment options for patients with relapsed/refractory multiple myeloma and renal impairment3.07Citations (PDF)
28Quality of life, psychological distress, and prognostic perceptions in patients with multiple myeloma
Cancer, 2022, 128, 1996-2004
4.133Citations (PDF)
29Extramedullary disease in multiple myeloma: a systematic literature review7.9223Citations (PDF)
30Defibrotide Therapy for SARS-CoV-2 ARDS
Chest, 2022, 162, 346-355
1.111Citations (PDF)
31Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma43.7390Citations (PDF)
32Melflufen for the treatment of multiple myeloma2.75Citations (PDF)
33Risk factors for the development of orthostatic hypotension during autologous stem cell transplant in patients with multiple myeloma
Leukemia and Lymphoma, 2022, 63, 2403-2412
1.55Citations (PDF)
34Gaps and opportunities in the treatment of relapsed-refractory multiple myeloma: Consensus recommendations of the NCI Multiple Myeloma Steering Committee7.950Citations (PDF)
35Lenalidomide, bortezomib and dexamethasone induction therapy for the treatment of newly diagnosed multiple myeloma: a practical review
British Journal of Haematology, 2022, 199, 190-204
2.418Citations (PDF)
36Daratumumab plus lenalidomide, bortezomib and dexamethasone in newly diagnosed multiple myeloma: Analysis of vascular thrombotic events in the <scp>GRIFFIN</scp> study
British Journal of Haematology, 2022, 199, 355-365
2.421Citations (PDF)
37Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica, 2021, 106, 1182-1187
4.130Citations (PDF)
38Analysis of Time to Complete Response after Defibrotide Initiation in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation2.05Citations (PDF)
39Efficacy and safety of oral panobinostat plus subcutaneous bortezomib and oral dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma (PANORAMA 3): an open-label, randomised, phase 2 study
Lancet Oncology, The, 2021, 22, 142-154
26.061Citations (PDF)
40Overall survival with oral selinexor plus low‐dose dexamethasone versus real‐world therapy in triple‐class‐refractory multiple myeloma
EJHaem, 2021, 2, 48-55
1.711Citations (PDF)
41Bortezomib, lenalidomide, and dexamethasone with or without elotuzumab in patients with untreated, high-risk multiple myeloma (SWOG-1211): primary analysis of a randomised, phase 2 trial
Lancet Haematology,the, 2021, 8, e45-e54
9.2115Citations (PDF)
42Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
Cell Reports, 2021, 34, 108532
6.4101Citations (PDF)
43Phase 1 open-label study of panobinostat, lenalidomide, bortezomib + dexamethasone in relapsed and relapsed/refractory multiple myeloma7.912Citations (PDF)
44A clinical perspective on plasma cell leukemia; current status and future directions7.956Citations (PDF)
45Molecular dynamics of targeting CD38 in multiple myeloma
British Journal of Haematology, 2021, 193, 581-591
2.425Citations (PDF)
46Expert review on soft‐tissue plasmacytomas in multiple myeloma: definition, disease assessment and treatment considerations
British Journal of Haematology, 2021, 194, 496-507
2.4144Citations (PDF)
47Oral ixazomib, lenalidomide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma
Blood, 2021, 137, 3616-3628
4.288Citations (PDF)
48Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group
Lancet Oncology, The, 2021, 22, e105-e118
26.0222Citations (PDF)
49Effect of prior treatments on selinexor, bortezomib, and dexamethasone in previously treated multiple myeloma30.915Citations (PDF)
50Bortezomib Induces Anti–Multiple Myeloma Immune Response Mediated by cGAS/STING Pathway Activation
Blood Cancer Discovery, 2021, 2, 468-483
4.9120Citations (PDF)
51Isatuximab plus pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma according to prior lines of treatment and refractory status: ICARIA-MM subgroup analysis
Leukemia Research, 2021, 104, 106576
0.729Citations (PDF)
52Final results of a phase 1b study of isatuximab short-duration fixed-volume infusion combination therapy for relapsed/refractory multiple myeloma
Leukemia, 2021, 35, 3526-3533
10.416Citations (PDF)
53Effect of age and frailty on the efficacy and tolerability of once‐weekly selinexor, bortezomib, and dexamethasone in previously treated multiple myeloma6.121Citations (PDF)
54Subgroup analysis of ICARIA‐MM study in relapsed/refractory multiple myeloma patients with high‐risk cytogenetics
British Journal of Haematology, 2021, 194, 120-131
2.446Citations (PDF)
55ERK signaling mediates resistance to immunomodulatory drugs in the bone marrow microenvironment
Science Advances, 2021, 7,
11.023Citations (PDF)
56Belantamab Mafodotin in Combination with Novel Agents in Relapsed/refractory Multiple Myeloma: DREAMM-5 Study Design
Future Oncology, 2021, 17, 1987-2003
2.430Citations (PDF)
57Is the Endothelium the Missing Link in the Pathophysiology and Treatment of COVID-19 Complications?2.142Citations (PDF)
58Panobinostat From Bench to Bedside: Rethinking the Treatment Paradigm for Multiple Myeloma1.018Citations (PDF)
59Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes3.914Citations (PDF)
60Targeting LAG3/GAL-3 to overcome immunosuppression and enhance anti-tumor immune responses in multiple myeloma
Leukemia, 2021, 36, 138-154
10.467Citations (PDF)
61Selinexor for the treatment of patients with previously treated multiple myeloma
Expert Review of Hematology, 2021, 14, 697-706
2.07Citations (PDF)
62Selinexor, bortezomib, and dexamethasone versus bortezomib and dexamethasone in previously treated multiple myeloma: Outcomes by cytogenetic risk
American Journal of Hematology, 2021, 96, 1120-1130
6.131Citations (PDF)
63Final Overall Survival Analysis of the TOURMALINE-MM1 Phase III Trial of Ixazomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Journal of Clinical Oncology, 2021, 39, 2430-2442
21.689Citations (PDF)
64Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in<i>BRAF</i>-Mutated Multiple Myeloma
Clinical Cancer Research, 2021, 27, 6432-6444
6.926Citations (PDF)
65Isatuximab for Relapsed/Refractory Multiple Myeloma: Review of Key Subgroup Analyses from the Phase III ICARIA-MM Study
Future Oncology, 2021, 17, 4797-4812
2.415Citations (PDF)
66A phase I/<scp>II</scp> study of ixazomib, pomalidomide, and dexamethasone for lenalidomide and proteasome inhibitor refractory multiple myeloma (Alliance <scp>A061202</scp>)
American Journal of Hematology, 2021, 96, 1595-1603
6.120Citations (PDF)
67Quality of life analyses in patients with multiple myeloma: results from the Selinexor (KPT-330) Treatment of Refractory Myeloma (STORM) phase 2b study
BMC Cancer, 2021, 21,
3.112Citations (PDF)
68Improving outcomes for patients with relapsed multiple myeloma: Challenges and considerations of current and emerging treatment options
Blood Reviews, 2021, 49, 100808
5.246Citations (PDF)
69The importance of endothelial protection: the emerging role of defibrotide in reversing endothelial injury and its sequelae
Bone Marrow Transplantation, 2021, 56, 2889-2896
3.317Citations (PDF)
70Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma
Nature Cell Biology, 2021, 23, 1199-1211
16.941Citations (PDF)
71Randomized Clinical Trial Representativeness and Outcomes in Real-World Patients: Comparison of 6 Hallmark Randomized Clinical Trials of Relapsed/Refractory Multiple Myeloma1.099Citations (PDF)
72A Phase Ib/II Trial of the First-in-Class Anti-CXCR4 Antibody Ulocuplumab in Combination with Lenalidomide or Bortezomib Plus Dexamethasone in Relapsed Multiple Myeloma
Clinical Cancer Research, 2020, 26, 344-353
6.992Citations (PDF)
73Incidence, Predictors, and Outcomes of Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Reduced-Intensity Allogeneic Hematopoietic Cell Transplantation1.621Citations (PDF)
74Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement
Lancet Haematology,the, 2020, 7, e61-e72
9.273Citations (PDF)
75Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study
Lancet Oncology, The, 2020, 21, 207-221
26.0715Citations (PDF)
76Proteasome inhibition for the treatment of glioblastoma4.038Citations (PDF)
77Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma
Blood, 2020, 136, 2513-2523
4.271Citations (PDF)
78Single-agent belantamab mafodotin for relapsed/refractory multiple myeloma: analysis of the lyophilised presentation cohort from the pivotal DREAMM-2 study7.948Citations (PDF)
79Isatuximab for the treatment of relapsed/refractory multiple myeloma3.136Citations (PDF)
80Phase 1 Trial Evaluating Vorinostat Plus Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma1.05Citations (PDF)
81Carfilzomib or bortezomib in combination with lenalidomide and dexamethasone for patients with newly diagnosed multiple myeloma without intention for immediate autologous stem-cell transplantation (ENDURANCE): a multicentre, open-label, phase 3, randomised, controlled trial
Lancet Oncology, The, 2020, 21, 1317-1330
26.0223Citations (PDF)
82Melflufen for relapsed and refractory multiple myeloma4.021Citations (PDF)
83Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial
Lancet, The, 2020, 396, 1563-1573
52.8289Citations (PDF)
84Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial
Blood, 2020, 136, 936-945
4.2618Citations (PDF)
85Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant13.9149Citations (PDF)
86The role of high‐dose melphalan with autologous stem‐cell transplant in multiple myeloma: is it time for a paradigm shift?
British Journal of Haematology, 2020, 191, 692-703
2.430Citations (PDF)
87c‐MYC expression and maturity phenotypes are associated with outcome benefit from addition of ixazomib to lenalidomide‐dexamethasone in myeloma1.99Citations (PDF)
88Real-world outcomes and factors impacting treatment choice in relapsed and/or refractory multiple myeloma (RRMM): a comparison of VRd, KRd, and IRd
Expert Review of Hematology, 2020, 13, 421-433
2.044Citations (PDF)
89Phase 1 study of the protein deubiquitinase inhibitor VLX1570 in patients with relapsed and/or refractory multiple myeloma
Investigational New Drugs, 2020, 38, 1448-1453
2.788Citations (PDF)
90Incidence of Anicteric Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome and Outcomes with Defibrotide following Hematopoietic Cell Transplantation in Adult and Pediatric Patients1.628Citations (PDF)
91Melflufen plus dexamethasone in relapsed and refractory multiple myeloma (O-12-M1): a multicentre, international, open-label, phase 1–2 study
Lancet Haematology,the, 2020, 7, e395-e407
9.271Citations (PDF)
92Selinexor for the treatment of multiple myeloma2.259Citations (PDF)
93Clinical benefit of ixazomib plus lenalidomide‐dexamethasone in myeloma patients with non‐canonical NF‐κB pathway activation1.919Citations (PDF)
94Randomized, placebo‐controlled, phase 3 study of perifosine combined with bortezomib and dexamethasone in patients with relapsed, refractory multiple myeloma previously treated with bortezomib
EJHaem, 2020, 1, 94-102
1.711Citations (PDF)
95Health-related quality-of-life results from the phase 3 OPTIMISMM study: pomalidomide, bortezomib, and low-dose dexamethasone versus bortezomib and low-dose dexamethasone in relapsed or refractory multiple myeloma
Leukemia and Lymphoma, 2020, 61, 1850-1859
1.512Citations (PDF)
96Pomalidomide, bortezomib, and dexamethasone for multiple myeloma previously treated with lenalidomide (OPTIMISMM): outcomes by prior treatment at first relapse
Leukemia, 2020, 35, 1722-1731
10.454Citations (PDF)
97Daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma: final results from the phase 2 GEN501 and SIRIUS trials
Lancet Haematology,the, 2020, 7, e447-e455
9.296Citations (PDF)
98Isatuximab plus pomalidomide and dexamethasone in relapsed/refractory multiple myeloma patients with renal impairment: ICARIA-MM subgroup analysis
Leukemia, 2020, 35, 562-572
10.461Citations (PDF)
99Melflufen: A Peptide–Drug Conjugate for the Treatment of Multiple Myeloma2.647Citations (PDF)
100Melflufen—A Novel Agent in the Treatment of Relapsed/Refractory Multiple Myeloma0.41Citations (PDF)
101Pomalidomide‐bortezomib‐dexamethasone in relapsed or refractory multiple myeloma: Japanese subset analysis of OPTIMISMM
Cancer Science, 2020, 111, 2116-2122
4.04Citations (PDF)
102HORIZON (OP-106): Melflufen Plus Dexamethasone (dex) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM) - Health-Related Quality of Life (HRQoL) Analysis
Blood, 2020, 136, 27-29
4.21Citations (PDF)
103Early Clinical Predictors of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Myeloablative Stem Cell Transplantation1.646Citations (PDF)
104Oral Selinexor–Dexamethasone for Triple-Class Refractory Multiple Myeloma43.7597Citations (PDF)
105Isatuximab plus pomalidomide and low-dose dexamethasone versus pomalidomide and low-dose dexamethasone in patients with relapsed and refractory multiple myeloma (ICARIA-MM): a randomised, multicentre, open-label, phase 3 study
Lancet, The, 2019, 394, 2096-2107
52.8569Citations (PDF)
106Phase I/II trial of the CXCR4 inhibitor plerixafor in combination with bortezomib as a chemosensitization strategy in relapsed/refractory multiple myeloma
American Journal of Hematology, 2019, 94, 1244-1253
6.155Citations (PDF)
107Recent developments with defibrotide for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome1.05Citations (PDF)
108Ixazomib, lenalidomide, and dexamethasone in patients with newly diagnosed multiple myeloma: long-term follow-up including ixazomib maintenance
Leukemia, 2019, 33, 1736-1746
10.447Citations (PDF)
109Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial
Lancet Oncology, The, 2019, 20, 781-794
26.0339Citations (PDF)
110A phase 1b study of isatuximab plus pomalidomide/dexamethasone in relapsed/refractory multiple myeloma
Blood, 2019, 134, 123-133
4.291Citations (PDF)
111Deciphering the chronology of copy number alterations in Multiple Myeloma7.946Citations (PDF)
112Selective targeting of multiple myeloma by B cell maturation antigen (BCMA)-specific central memory CD8+ cytotoxic T lymphocytes: immunotherapeutic application in vaccination and adoptive immunotherapy
Leukemia, 2019, 33, 2208-2226
10.428Citations (PDF)
113Ixazomib maintenance therapy in newly diagnosed multiple myeloma: An integrated analysis of four phase I/II studies1.912Citations (PDF)
114Systematic review of defibrotide studies in the treatment of veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS)
Bone Marrow Transplantation, 2019, 54, 1951-1962
3.366Citations (PDF)
115Performance of the International Myeloma Working Group myeloma frailty score among patients 75 and older1.837Citations (PDF)
116Autologous Stem-Cell Transplantation Outcomes for Relapsed Metastatic Germ-Cell Tumors in the Modern Era
Clinical Genitourinary Cancer, 2019, 17, 58-64.e1
2.49Citations (PDF)
117A Phase I/II Study of Evofosfamide, A Hypoxia-activated Prodrug with or without Bortezomib in Subjects with Relapsed/Refractory Multiple Myeloma
Clinical Cancer Research, 2019, 25, 478-486
6.941Citations (PDF)
118Ibrutinib alone or with dexamethasone for relapsed or relapsed and refractory multiple myeloma: phase 2 trial results
British Journal of Haematology, 2018, 180, 821-830
2.434Citations (PDF)
119Isatuximab Plus Pomalidomide/Dexamethasone Versus Pomalidomide/Dexamethasone in Relapsed/Refractory Multiple Myeloma: Icaria Phase Iii Study Design
Future Oncology, 2018, 14, 1035-1047
2.469Citations (PDF)
120Defibrotide sodium for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome2.730Citations (PDF)
121Current use of monoclonal antibodies in the treatment of multiple myeloma
British Journal of Haematology, 2018, 181, 447-459
2.444Citations (PDF)
122Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing
Leukemia, 2018, 32, 1838-1841
10.454Citations (PDF)
123Association between response kinetics and outcomes in relapsed/refractory multiple myeloma: analysis from TOURMALINE-MM1
Leukemia, 2018, 32, 2032-2036
10.414Citations (PDF)
124A phase 1 clinical trial evaluating marizomib, pomalidomide and low‐dose dexamethasone in relapsed and refractory multiple myeloma (<scp>NPI</scp>‐0052‐107): final study results2.471Citations (PDF)
125CD38 antibodies in multiple myeloma: back to the future
Blood, 2018, 131, 13-29
4.2417Citations (PDF)
126The use of defibrotide in blood and marrow transplantation
Blood Advances, 2018, 2, 1495-1509
5.166Citations (PDF)
127Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting7.9216Citations (PDF)
128The power of proteasome inhibition in multiple myeloma
Expert Review of Proteomics, 2018, 15, 1033-1052
2.134Citations (PDF)
129Targeting B-cell maturation antigen with GSK2857916 antibody–drug conjugate in relapsed or refractory multiple myeloma (BMA117159): a dose escalation and expansion phase 1 trial
Lancet Oncology, The, 2018, 19, 1641-1653
26.0226Citations (PDF)
130Ixazomib for the treatment of multiple myeloma2.260Citations (PDF)
131Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma
New England Journal of Medicine, 2018, 379, 1811-1822
43.7495Citations (PDF)
132Minimal residual disease negativity using deep sequencing is a major prognostic factor in multiple myeloma
Blood, 2018, 132, 2456-2464
4.2378Citations (PDF)
133Elotuzumab plus lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: Extended 4‐year follow‐up and analysis of relative progression‐free survival from the randomized ELOQUENT‐2 trial
Cancer, 2018, 124, 4032-4043
4.1127Citations (PDF)
134Patient‐reported outcomes of multiple myeloma patients treated with panobinostat after ≥2 lines of therapy based on the international phase 3, randomized, double‐blind, placebo‐controlled <scp>PANORAMA</scp>‐1 trial
British Journal of Haematology, 2018, 181, 628-636
2.422Citations (PDF)
135Elotuzumab monotherapy in patients with smouldering multiple myeloma: a phase 2 study
British Journal of Haematology, 2018, 182, 495-503
2.436Citations (PDF)
136Final results from a defibrotide treatment‐<scp>IND</scp> study for patients with hepatic veno‐occlusive disease/sinusoidal obstruction syndrome
British Journal of Haematology, 2018, 181, 816-827
2.4119Citations (PDF)
137How I treat the young patient with multiple myeloma
Blood, 2018, 132, 1114-1124
4.241Citations (PDF)
138Twice‐weekly ixazomib in combination with lenalidomide‐dexamethasone in patients with newly diagnosed multiple myeloma
British Journal of Haematology, 2018, 182, 231-244
2.432Citations (PDF)
139Maintenance and continuous therapy for multiple myeloma2.613Citations (PDF)
140Trial designs for chemotherapy-induced peripheral neuropathy prevention
Neurology, 2018, 91, 403-413
1.082Citations (PDF)
141A phase 2 study of modified lenalidomide, bortezomib and dexamethasone in transplant‐ineligible multiple myeloma
British Journal of Haematology, 2018, 182, 222-230
2.4147Citations (PDF)
142Patient‐reported health‐related quality of life from the phase III TOURMALINE‐MM1 study of ixazomib‐lenalidomide‐dexamethasone versus placebo‐lenalidomide‐dexamethasone in relapsed/refractory multiple myeloma6.143Citations (PDF)
143Investigational agents in immunotherapy: a new horizon for the treatment of multiple myeloma
British Journal of Haematology, 2018, 181, 433-446
2.439Citations (PDF)
144Defibrotide for the treatment of hepatic veno‐occlusive disease/sinusoidal obstruction syndrome following nontransplant‐associated chemotherapy: Final results from a post hoc analysis of data from an expanded‐access program1.432Citations (PDF)
145APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications
Leukemia, 2018, 33, 426-438
10.473Citations (PDF)
146Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma
Clinical Cancer Research, 2017, 23, 3307-3315
6.9243Citations (PDF)
147Deacetylase inhibitors: an advance in myeloma therapy?
Expert Review of Hematology, 2017, 10, 229-237
2.026Citations (PDF)
148p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma
Blood, 2017, 129, 1308-1319
4.244Citations (PDF)
149Management of adverse events associated with ixazomib plus lenalidomide/dexamethasone in relapsed/refractory multiple myeloma
British Journal of Haematology, 2017, 178, 571-582
2.453Citations (PDF)
150A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for the treatment of multiple myeloma: towards providing a benchmark for the cardiac safety profile of proteasome inhibition in multiple myeloma
British Journal of Haematology, 2017, 178, 547-560
2.449Citations (PDF)
151Earlier defibrotide initiation post‐diagnosis of veno‐occlusive disease/sinusoidal obstruction syndrome improves Day +100 survival following haematopoietic stem cell transplantation
British Journal of Haematology, 2017, 178, 112-118
2.487Citations (PDF)
152Adverse event management in patients with relapsed and refractory multiple myeloma taking pomalidomide plus low‐dose dexamethasone: A pooled analysis1.924Citations (PDF)
153Impact of concomitant dexamethasone dosing schedule on bortezomib‐induced peripheral neuropathy in multiple myeloma
British Journal of Haematology, 2017, 178, 756-763
2.423Citations (PDF)
154Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma
New England Journal of Medicine, 2017, 376, 1311-1320
43.71,143Citations (PDF)
155IgM myeloma: A multicenter retrospective study of 134 patients6.152Citations (PDF)
156Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group
Lancet Oncology, The, 2017, 18, e206-e217
26.0486Citations (PDF)
157Defibrotide for Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome: Interim Results from a Treatment IND Study1.654Citations (PDF)
158Ixazomib significantly prolongs progression-free survival in high-risk relapsed/refractory myeloma patients
Blood, 2017, 130, 2610-2618
4.2109Citations (PDF)
159Realgar nanoparticles <i>versus </i><scp>ATO</scp> arsenic compounds induce <i>in vitro</i> and <i>in vivo</i> activity <i>against</i> multiple myeloma
British Journal of Haematology, 2017, 179, 756-771
2.438Citations (PDF)
160Dose and Schedule Selection of the Oral Proteasome Inhibitor Ixazomib in Relapsed/Refractory Multiple Myeloma: Clinical and Model-Based Analyses
Targeted Oncology, 2017, 12, 643-654
3.320Citations (PDF)
161Defibrotide for children and adults with hepatic veno-occlusive disease post hematopoietic cell transplantation2.528Citations (PDF)
162Updated analysis of CALGB (Alliance) 100104 assessing lenalidomide versus placebo maintenance after single autologous stem-cell transplantation for multiple myeloma: a randomised, double-blind, phase 3 trial
Lancet Haematology,the, 2017, 4, e431-e442
9.2155Citations (PDF)
163Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women10.432Citations (PDF)
164IgA multiple myeloma in a patient with an IgG pemphigus foliaceus‐like exanthem2.22Citations (PDF)
165Treatment-free interval as a metric of patient experience and a health outcome of value for advanced multiple myeloma: the case for the histone deacetylase inhibitor panobinostat, a next-generation novel agent
Expert Review of Hematology, 2017, 10, 933-939
2.012Citations (PDF)
166Elotuzumab plus lenalidomide/dexamethasone for relapsed or refractory multiple myeloma: <scp>ELOQUENT</scp>‐2 follow‐up and <i>post‐hoc</i> analyses on progression‐free survival and tumour growth
British Journal of Haematology, 2017, 178, 896-905
2.4128Citations (PDF)
167Impact of prior therapy on the efficacy and safety of oral ixazomib-lenalidomide-dexamethasone <i>vs</i> . placebo-lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma in TOURMALINE-MM1
Haematologica, 2017, 102, 1767-1775
4.152Citations (PDF)
168The proteasome and proteasome inhibitors in multiple myeloma7.2304Citations (PDF)
169Lenalidomide in combination or alone as maintenance therapy following autologous stem cell transplant in patients with multiple myeloma: a review of options for and against2.210Citations (PDF)
170Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma1.044Citations (PDF)
171Pomalidomide, bortezomib, and dexamethasone for patients with relapsed lenalidomide-refractory multiple myeloma
Blood, 2017, 130, 1198-1204
4.261Citations (PDF)
172Panobinostat plus bortezomib and dexamethasone: impact of dose intensity and administration frequency on safety in the <scp>PANORAMA</scp> 1 trial2.420Citations (PDF)
173Deacetylase inhibitors as a novel modality in the treatment of multiple myeloma
Pharmacological Research, 2017, 117, 185-191
9.428Citations (PDF)
174Cardiovascular and Thrombotic Complications of Novel Multiple Myeloma Therapies
JAMA Oncology, 2017, 3, 980
14.695Citations (PDF)
175Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome with Multiorgan Failure2.631Citations (PDF)
176New developments in the management of relapsed/refractory multiple myeloma &amp;ndash; the role of ixazomib
Journal of Blood Medicine, 2017, Volume 8, 107-121
2.419Citations (PDF)
177Randomized, double-blind, placebo-controlled phase III study of ixazomib plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma: China Continuation study30.962Citations (PDF)
178Melflufen - a peptidase-potentiated alkylating agent in clinical trials
Oncotarget, 2017, 8, 66641-66655
1.779Citations (PDF)
179Influence of Disease and Patient Characteristics on Daratumumab Exposure and Clinical Outcomes in Relapsed or Refractory Multiple Myeloma
Clinical Pharmacokinetics, 2017, 57, 529-538
3.626Citations (PDF)
180A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications
Oncotarget, 2016, 7, 77326-77341
1.757Citations (PDF)
181Safety of Live-attenuated Zoster Vaccination in Multiple Myeloma Patients Receiving Maintenance Lenalidomide after Autologous Stem Cell Transplantation.0.80Citations (PDF)
182Safety of MMR Vaccination in Multiple Myeloma Patients Receiving Maintenance Lenalidomide or Bortezomib after Autologous Stem Cell Transplantation.0.80Citations (PDF)
183<scp>TAK</scp>‐228 (formerly <scp>MLN</scp>0128), an investigational oral dual <scp>TORC</scp>1/2 inhibitor: A phase I dose escalation study in patients with relapsed or refractory multiple myeloma, non‐Hodgkin lymphoma, or Waldenström's macroglobulinemia6.194Citations (PDF)
184Clinical utility of C‐terminal telopeptide of type 1 collagen in multiple myeloma2.412Citations (PDF)
185Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma
Blood, 2016, 128, 1821-1828
4.2106Citations (PDF)
186Defibrotide for Treatment of Severe Veno-Occlusive Disease in Pediatrics and Adults: An Exploratory Analysis Using Data from the Center for International Blood and Marrow Transplant Research1.655Citations (PDF)
187Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma
New England Journal of Medicine, 2016, 374, 1621-1634
43.7985Citations (PDF)
188Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells
Blood, 2016, 127, 1138-1150
4.2109Citations (PDF)
189Clinical efficacy and management of monoclonal antibodies targeting CD38 and SLAMF7 in multiple myeloma
Blood, 2016, 127, 681-695
4.2193Citations (PDF)
190Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure
Blood, 2016, 127, 1656-1665
4.2303Citations (PDF)
191Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1
Blood, 2016, 127, 2693-2700
4.275Citations (PDF)
192Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma
Blood, 2016, 128, 37-44
4.2379Citations (PDF)
193Panobinostat plus bortezomib and dexamethasone in previously treated multiple myeloma: outcomes by prior treatment
Blood, 2016, 127, 713-721
4.2129Citations (PDF)
194Phase 1 Study of Tabalumab, a Human Anti-B-Cell Activating Factor Antibody, and Bortezomib in Patients with Relapsed/Refractory Multiple Myeloma
Clinical Cancer Research, 2016, 22, 5688-5695
6.921Citations (PDF)
195Daratumumab, Lenalidomide, and Dexamethasone for Multiple Myeloma
New England Journal of Medicine, 2016, 375, 1319-1331
43.71,360Citations (PDF)
196Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease: Final Results From the International Compassionate-Use Program1.687Citations (PDF)
197Marizomib irreversibly inhibits proteasome to overcome compensatory hyperactivation in multiple myeloma and solid tumour patients
British Journal of Haematology, 2016, 174, 711-720
2.450Citations (PDF)
198Update on elotuzumab, a novel anti-SLAMF7 monoclonal antibody for the treatment of multiple myeloma3.115Citations (PDF)
199Ricolinostat plus lenalidomide, and dexamethasone in relapsed or refractory multiple myeloma: a multicentre phase 1b trial
Lancet Oncology, The, 2016, 17, 1569-1578
26.0187Citations (PDF)
200APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment
Blood, 2016, 127, 3225-3236
4.2304Citations (PDF)
201International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma
Lancet Oncology, The, 2016, 17, e328-e346
26.02,576Citations (PDF)
202Overall survival of patients with relapsed multiple myeloma treated with panobinostat or placebo plus bortezomib and dexamethasone (the PANORAMA 1 trial): a randomised, placebo-controlled, phase 3 trial
Lancet Haematology,the, 2016, 3, e506-e515
9.2142Citations (PDF)
203Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma7.6135Citations (PDF)
204A novel alkylating agent Melflufen induces irreversible <scp>DNA</scp> damage and cytotoxicity in multiple myeloma cells
British Journal of Haematology, 2016, 174, 397-409
2.456Citations (PDF)
205Multiple Myeloma in Pregnancy—A Review of the Literature and a Case Series1.014Citations (PDF)
206Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution
Clinical Cancer Research, 2016, 22, 4206-4214
6.929Citations (PDF)
207Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial
Lancet, The, 2016, 387, 1551-1560
52.8801Citations (PDF)
208The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival13.9102Citations (PDF)
209Panobinostat for the treatment of relapsed or relapsed/refractory multiple myeloma: pharmacology and clinical outcomes2.727Citations (PDF)
210Hematopoietic Cell Transplantation in Patients with Medication-Related Osteonecrosis of the Jaws1.64Citations (PDF)
211First in Human Study with GSK2857916, an Antibody Drug Conjugated to Microtubule-Disrupting Agent Directed Against B-Cell Maturation Antigen (BCMA) in Patients with Relapsed/Refractory Multiple Myeloma (MM): Results from Study BMA117159 Part 1 Dose Escalation
Blood, 2016, 128, 1148-1148
4.224Citations (PDF)
212Final Results of a Phase 1/2 Open-Label Study to Assess the Safety, Tolerability and Preliminary Efficacy of Evofosfamide, a Hypoxia-Activated Prodrug, and Dexamethasone with or without Bortezomib in Subjects with Relapsed/Refractory Multiple Myeloma
Blood, 2016, 128, 2122-2122
4.21Citations (PDF)
213Preliminary Results from a Phase Ib Study of Isatuximab in Combination with Pomalidomide and Dexamethasone in Relapsed and Refractory Multiple Myeloma
Blood, 2016, 128, 2123-2123
4.219Citations (PDF)
214Higher c-MYC Expression Is Associated with Ixazomib-Lenalidomide-Dexamethasone (IRd) Progression-Free Survival (PFS) Benefit Versus Placebo-Rd: Biomarker Analysis of the Phase 3 Tourmaline-MM1 Study in Relapsed/Refractory Multiple Myeloma (RRMM)
Blood, 2016, 128, 243-243
4.23Citations (PDF)
215Pmd-107: Marizomib, Pomalidomide and Low Dose-Dexamethasone Combination Study in Relapsed/Refractory Multiple Myeloma (NCT02103335): Full Enrollment Results from a Phase-1 Multicenter, Open Label Study
Blood, 2016, 128, 3326-3326
4.26Citations (PDF)
216Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study
Blood, 2016, 128, 66-66
4.23Citations (PDF)
217Final Results of a Phase 2 Trial of Extended Treatment (tx) with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (KRd) Plus Autologous Stem Cell Transplantation (ASCT) in Newly Diagnosed Multiple Myeloma (NDMM)
Blood, 2016, 128, 675-675
4.238Citations (PDF)
218Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma
Blood, 2016, 128, 976-976
4.220Citations (PDF)
219IgM Myeloma: A Multicenter Retrospective Study of 159 Patients
Blood, 2016, 128, 3276-3276
4.20Citations (PDF)
220Longer Time to Best Response and Depth of Response Are Associated with Improved Duration of Best Achieved Response and Progression-Free Survival (PFS): Post-Hoc Analysis of Phase 3 Tourmaline-MM1 Trial in Relapsed/Refractory Multiple Myeloma (RRMM)
Blood, 2016, 128, 2134-2134
4.20Citations (PDF)
221Identification and Validation of HLA-A24 XBP1us, XBP1sp, CD138, and CS1 Peptides to Generate Antigens Specific-Cytotoxic T Lymphocytes: Preclinical Basis for Vaccine Therapy in HLA-A24 Patients with Multiple Myeloma and Other Cancers
Blood, 2016, 128, 5689-5689
4.21Citations (PDF)
222Resolving the daratumumab interference with blood compatibility testing
Transfusion, 2015, 55, 1545-1554
0.8222Citations (PDF)
223Retrospective matched-pairs analysis of bortezomib plus dexamethasone versus bortezomib monotherapy in relapsed multiple myeloma
Haematologica, 2015, 100, 100-106
4.132Citations (PDF)
224Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report
Blood, 2015, 125, 2068-2074
4.2699Citations (PDF)
225Synergistic anti-myeloma activity of the proteasome inhibitor marizomib and the IMiD<sup>®</sup>immunomodulatory drug pomalidomide
British Journal of Haematology, 2015, 171, 798-812
2.446Citations (PDF)
226Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells
PLoS ONE, 2015, 10, e0143847
2.422Citations (PDF)
227Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma43.71,254Citations (PDF)
228Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b–2 dose-escalation study
Lancet Haematology,the, 2015, 2, e516-e527
9.2145Citations (PDF)
229Defibrotide for the treatment of severe hepatic veno-occlusive disease/sinusoidal obstruction syndrome: evidence for clinical benefit
Expert Opinion on Orphan Drugs, 2015, 3, 1491-1501
1.01Citations (PDF)
230Effect of cumulative bortezomib dose on survival in multiple myeloma patients receiving bortezomib‐melphalan‐prednisone in the phase III VISTA study6.163Citations (PDF)
231Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease: An Analysis of Clinical Benefit As Determined By Number Needed to Treat (NNT) to Achieve Complete Response and to Improve Survival1.63Citations (PDF)
232Management of Relapsed Multiple Myeloma after Autologous Stem Cell Transplant1.624Citations (PDF)
233Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma
Clinical Cancer Research, 2015, 21, 4607-4618
6.9298Citations (PDF)
234Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma
Cancer Discovery, 2015, 5, 972-987
25.6105Citations (PDF)
235CD38-Targeted Immunochemotherapy in Refractory Multiple Myeloma: A New Horizon
Clinical Cancer Research, 2015, 21, 2660-2662
6.941Citations (PDF)
236Proteomic profiling of naïve multiple myeloma patient plasma cells identifies pathways associated with favourable response to bortezomib‐based treatment regimens2.419Citations (PDF)
237The Investigational Proteasome Inhibitor Ixazomib for the Treatment of Multiple Myeloma
Future Oncology, 2015, 11, 1153-1168
2.426Citations (PDF)
238Development of extramedullary myeloma in the era of novel agents: no evidence of increased risk with lenalidomide–bortezomib combinations
British Journal of Haematology, 2015, 169, 843-850
2.477Citations (PDF)
239Targeting CD38 with Daratumumab Monotherapy in Multiple Myeloma
New England Journal of Medicine, 2015, 373, 1207-1219
43.71,058Citations (PDF)
240Panobinostat for the Treatment of Multiple Myeloma
Clinical Cancer Research, 2015, 21, 4767-4773
6.9257Citations (PDF)
241Ricolinostat (ACY-1215), the First Selective HDAC6 Inhibitor, in Combination with Bortezomib and Dexamethasone in Patients with Relapsed or Relapsed-and-Refractory Multiple Myeloma: Phase 1b Results (ACY-100 Study)
Blood, 2015, 126, 1827-1827
4.210Citations (PDF)
242Mutational Profile and Prognostic Relevance of Circulating Tumor Cells in Multiple Myeloma
Blood, 2015, 126, 23-23
4.237Citations (PDF)
243Eloquent-2 Update: A Phase 3, Randomized, Open-Label Study of Elotuzumab in Combination with Lenalidomide/Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma - 3-Year Safety and Efficacy Follow-up
Blood, 2015, 126, 28-28
4.222Citations (PDF)
244A Novel Agent SL-401 Triggers Anti-Myeloma Activity By Targeting Plasmacytoid Dendritic Cells: Implications for a Novel Immune-Associated Mechanism
Blood, 2015, 126, 3000-3000
4.21Citations (PDF)
245Efficacy of Melflufen, a Peptidase Targeted Therapy, and Dexamethasone in an Ongoing Open-Label Phase 2a Study in Patients with Relapsed and Relapsed-Refractory Multiple Myeloma (RRMM) Including an Initial Report on Progression Free Survival
Blood, 2015, 126, 3029-3029
4.21Citations (PDF)
246Analysis of Pomalidomide Plus Low-Dose Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma with Vs without Moderate Renal Impairment
Blood, 2015, 126, 3031-3031
4.23Citations (PDF)
247A Phase 1, Multicenter Study of Pomalidomide, Bortezomib, and Low-Dose Dexamethasone in Patients with Proteasome Inhibitor Exposed and Lenalidomide-Refractory Myeloma (Trial MM-005)
Blood, 2015, 126, 3036-3036
4.212Citations (PDF)
248ACY-241, a Novel, HDAC6 Selective Inhibitor: Synergy with Immunomodulatory (IMiD®) Drugs in Multiple Myeloma (MM) Cells and Early Clinical Results (ACE-MM-200 Study)
Blood, 2015, 126, 3040-3040
4.220Citations (PDF)
249Ricolinostat (ACY-1215), the First Selective HDAC6 Inhibitor, in Combonation with Lenalidomide and Dexamethasone in Patients with Relapsed and Relapsed-and-Refractory Multiple Myeloma: Phase 1b Results (ACE-MM-101 Study)
Blood, 2015, 126, 3055-3055
4.27Citations (PDF)
250Alliance A061202. a Phase I/II Study of Pomalidomide, Dexamethasone and Ixazomib Versus Pomalidomide and Dexamethasone for Patients with Multiple Myeloma Refractory to Lenalidomide and Proteasome Inhibitor Based Therapy: Phase I Results
Blood, 2015, 126, 375-375
4.219Citations (PDF)
251Autologous Transplantation for Multiple Myeloma in the Era of New Drugs: A Phase III Study of the Intergroupe Francophone Du Myelome (IFM/DFCI 2009 Trial)
Blood, 2015, 126, 391-391
4.2102Citations (PDF)
252Prospective Evaluation of MRI and PET-CT at Diagnosis and before Maintenance Therapy in Symptomatic Patients with Multiple Myeloma Included in the IFM/DFCI 2009 Trial
Blood, 2015, 126, 395-395
4.222Citations (PDF)
253A Phase II Study of Modified Lenalidomide, Bortezomib, and Dexamethasone (RVD-lite) for Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma
Blood, 2015, 126, 4217-4217
4.28Citations (PDF)
254Phase 1, Multicenter, Open-Label, Combination Study (NPI-0052-107; NCT02103335) of Pomalidomide (POM), Marizomib (MRZ, NPI-0052), and Low-Dose Dexamethasone (LD-DEX) in Patients with Relapsed and Refractory Multiple Myeloma
Blood, 2015, 126, 4220-4220
4.27Citations (PDF)
255Ricolinostat (ACY-1215), the First Selective HDAC6 Inhibitor, Combines Safely with Pomalidomide and Dexamethasone and Shows Promosing Early Results in Relapsed-and-Refractory Myeloma (ACE-MM-102 Study)
Blood, 2015, 126, 4228-4228
4.220Citations (PDF)
256Updated Results of a Phase 1/2a, Dose Escalation Study of Pvx-410 Multi-Peptide Cancer Vaccine in Patients with Smoldering Multiple Myeloma (SMM)
Blood, 2015, 126, 4246-4246
4.22Citations (PDF)
257Final Results of the Phase I/II Study of Chemosensitization Using the CXCR4 Inhibitor Plerixafor in Combination with Bortezomib in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma
Blood, 2015, 126, 4256-4256
4.24Citations (PDF)
258Daratumumab in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed or Relapsed and Refractory Multiple Myeloma: Updated Results of a Phase 1/2 Study (GEN503)
Blood, 2015, 126, 507-507
4.230Citations (PDF)
259Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome with Multi-Organ Dysfunction: Final Results from a Pivotal, Historically Controlled, Phase 3 Trial
Blood, 2015, 126, 737-737
4.21Citations (PDF)
260Activation of Lysosomal Function and Reactive Oxygen Species Play Crucial Roles in SAR650984-Induced Direct Killing of Human Multiple Myeloma Cells with Mutated p53, Which Is Further Augmented By Pomalidomide
Blood, 2015, 126, 4253-4253
4.20Citations (PDF)
261Low-Risk Multiple Myeloma By SKY92+ISS Validated in the Multiple Myeloma Genomics Initiative Study
Blood, 2015, 126, 5322-5322
4.20Citations (PDF)
262Targeting Replicative Stress to Treat Hematological Disorders
Blood, 2015, 126, 2419-2419
4.20Citations (PDF)
263A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance
Blood, 2014, 123, 706-716
4.2284Citations (PDF)
264Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition
Cancer Research, 2014, 74, 4458-4469
0.672Citations (PDF)
265Best Treatment Strategies in High-Risk Multiple Myeloma: Navigating a Gray Area
Journal of Clinical Oncology, 2014, 32, 2125-2132
21.623Citations (PDF)
266Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients
Blood, 2014, 124, 1038-1046
4.2200Citations (PDF)
267Early or delayed transplantation for multiple myeloma in the era of novel therapy: does one size fit all?2.925Citations (PDF)
268Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study
Lancet Oncology, The, 2014, 15, 1503-1512
26.0249Citations (PDF)
269Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide
British Journal of Haematology, 2014, 166, 401-409
2.439Citations (PDF)
270Biomarkers of Bone Remodeling in Multiple Myeloma Patients to Tailor Bisphosphonate Therapy
Clinical Cancer Research, 2014, 20, 3955-3961
6.936Citations (PDF)
271A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma
Blood, 2014, 123, 1461-1469
4.2181Citations (PDF)
272Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy
Cancer Cell, 2014, 25, 91-101
38.5918Citations (PDF)
273Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data
Lancet Oncology, The, 2014, 15, 333-342
26.0271Citations (PDF)
274Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
Nature Medicine, 2014, 20, 599-606
39.5281Citations (PDF)
275Heterogeneity of genomic evolution and mutational profiles in multiple myeloma13.9818Citations (PDF)
276International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation
Journal of Clinical Oncology, 2014, 32, 587-600
21.6373Citations (PDF)
277International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma
Lancet Oncology, The, 2014, 15, e538-e548
26.04,298Citations (PDF)
278Novel Targeted Agents in the Treatment of Multiple Myeloma2.317Citations (PDF)
279Allogeneic Transplantation in Multiple Myeloma: A Potential Renaissance in the Era of Novel Therapies?1.61Citations (PDF)
280Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial
Lancet Oncology, The, 2014, 15, 1195-1206
26.0753Citations (PDF)
281The challenge of cross-trial comparisons using limited data
Haematologica, 2014, 99, e145-e146
4.17Citations (PDF)
282Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy
Blood, 2014, 123, 632-639
4.2111Citations (PDF)
283Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma
Blood, 2014, 123, 3128-3138
4.2450Citations (PDF)
284Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study
Blood, 2014, 123, 1826-1832
4.2355Citations (PDF)
285Differential and limited expression of mutant alleles in multiple myeloma
Blood, 2014, 124, 3110-3117
4.255Citations (PDF)
286Bortezomib cumulative dose, efficacy, and tolerability with three different bortezomib-melphalan-prednisone regimens in previously untreated myeloma patients ineligible for high-dose therapy
Haematologica, 2014, 99, 1114-1122
4.148Citations (PDF)
287Current treatment landscape for relapsed and/or refractory multiple myeloma75.5191Citations (PDF)
288Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease: An Update from the International Compassionate Use Program in 710 Patients
Blood, 2014, 124, 1138-1138
4.21Citations (PDF)
289Identification Rate of Myeloma-Specific Clonotypes in Multiple Diagnostic Sample Types from Patients with Multiple Myeloma Using Next-Generation Sequencing Method
Blood, 2014, 124, 2036-2036
4.21Citations (PDF)
290Characterization of the Incidence and Management of Gastrointestinal Toxicity in the Phase 3 Panorama 1 Study of Panobinostat Plus Bortezomib and Dexamethasone Versus Placebo Plus Bortezomib and Dexamethasone in Patients with Relapsed or Relapsed and Refractory Multiple Myeloma
Blood, 2014, 124, 2120-2120
4.24Citations (PDF)
291Final Results of Phase I/II Trial of the Oral mTOR Inhibitor Everolimus (RAD001) in Combination with Bortezomib and Rituximab (RVR) in Relapsed or Refractory Waldenstrom Macroglobulinemia
Blood, 2014, 124, 3081-3081
4.216Citations (PDF)
292Ibrutinib, Single Agent or in Combination with Dexamethasone, in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Preliminary Phase 2 Results
Blood, 2014, 124, 31-31
4.211Citations (PDF)
293Oprozomib and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma: Initial Results from the Dose Escalation Portion of a Phase 1b/2, Multicenter, Open-Label Study
Blood, 2014, 124, 3453-3453
4.217Citations (PDF)
294Phase Ib Study of the Novel Anti-CXCR4 Antibody Ulocuplumab (BMS-936564) in Combination with Lenalidomide Plus Low-Dose Dexamethasone, or with Bortezomib plus Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma
Blood, 2014, 124, 3483-3483
4.214Citations (PDF)
295Phase 1B Results of Ricolinostat (ACY-1215) Combination Therapy with Bortezomib and Dexamethasone in Patients with Relapsed or Relapsed and Refractory Multiple Myeloma (MM)
Blood, 2014, 124, 4764-4764
4.213Citations (PDF)
296Ricolinostat (ACY-1215), a Selective HDAC6 Inhibitor, in Combination with Lenalidomide and Dexamethasone: Results of a Phase 1b Trial in Relapsed and Relapsed Refractory Multiple Myeloma
Blood, 2014, 124, 4772-4772
4.28Citations (PDF)
297Alternative Splicing Is a Frequent Event and Impacts Clinical Outcome in Myeloma: A Large RNA-Seq Data Analysis of Newly-Diagnosed Myeloma Patients
Blood, 2014, 124, 638-638
4.226Citations (PDF)
298Long-Term Ixazomib Maintenance Is Tolerable and Improves Depth of Response Following Ixazomib-Lenalidomide-Dexamethasone Induction in Patients (Pts) with Previously Untreated Multiple Myeloma (MM): Phase 2 Study Results
Blood, 2014, 124, 82-82
4.219Citations (PDF)
299SL-401, a Novel Targeted Therapy Directed to the Interleukin-3 Receptor (IL-3R), Blocks Plasmacytoid Dendritic Cell (pDC)-Triggered Myeloma Cell Growth and Prevents Osteoclastogenesis
Blood, 2014, 124, 3441-3441
4.226Citations (PDF)
300Mimicking Myeloma Niche Ex Vivo
Blood, 2014, 124, 2076-2076
4.20Citations (PDF)
301Evaluation of Immune Profile in Patients with Multiple Myeloma Using Cytof Technology
Blood, 2014, 124, 3404-3404
4.20Citations (PDF)
302Targeting Immune Suppressive Microenvironment By Immune Checkpoint Blockade in Multiple Myeloma
Blood, 2014, 124, 27-27
4.22Citations (PDF)
303Updated Results from a Large, Ongoing, Treatment IND Study Using Defibrotide for Patients with Hepatic Veno-Occlusive Disease
Blood, 2014, 124, 2470-2470
4.20Citations (PDF)
304Inter and Intra-Clonal Heterogeneity in Multiple Myeloma and Waldenstrom Macroglobulinemia
Blood, 2014, 124, 2070-2070
4.20Citations (PDF)
305Histone Deacetylase Inhibitors in Multiple Myeloma: Rationale and Evidence for Their Use in Combination Therapy1.041Citations (PDF)
306Conservative management of bisphosphonate-related osteonecrosis of the jaws: Staging and treatment outcomes
Oral Oncology, 2013, 49, 977-983
2.551Citations (PDF)
307The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias2.265Citations (PDF)
308Evolving Strategies in the Initial Treatment of Multiple Myeloma
Seminars in Oncology, 2013, 40, 592-601
1.95Citations (PDF)
309Clinical Translation in Multiple Myeloma: From Bench to Bedside
Seminars in Oncology, 2013, 40, 549-553
1.99Citations (PDF)
310Preclinical data and early clinical experience supporting the use of histone deacetylase inhibitors in multiple myeloma
Leukemia Research, 2013, 37, 829-837
0.748Citations (PDF)
311Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans
Blood, 2013, 121, 2975-2987
4.2376Citations (PDF)
312Pomalidomide: New immunomodulatory agent with potent antiproliferative effects5.236Citations (PDF)
313Endothelial stress products and coagulation markers in patients with multiple myeloma treated with lenalidomide plus dexamethasone: an observational study
British Journal of Haematology, 2013, 160, 351-358
2.420Citations (PDF)
314New Insights into the Treatment of Multiple Myeloma with Histone Deacetylase Inhibitors2.439Citations (PDF)
315<i>In Vitro</i> and <i>In Vivo</i> Antitumor Activity of a Novel Alkylating Agent, Melphalan-Flufenamide, against Multiple Myeloma Cells
Clinical Cancer Research, 2013, 19, 3019-3031
6.998Citations (PDF)
316Kidney Disease and Multiple Myeloma4.4145Citations (PDF)
317Drug safety evaluation of defibrotide2.776Citations (PDF)
318Phase 1 study of pomalidomide MTD, safety, and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib
Blood, 2013, 121, 1961-1967
4.2161Citations (PDF)
319PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma
Blood, 2013, 122, 2331-2337
4.2289Citations (PDF)
320Intracellular NAD+ depletion enhances bortezomib-induced anti-myeloma activity
Blood, 2013, 122, 1243-1255
4.279Citations (PDF)
321The impact of ASCT on patients with newly diagnosed multiple myeloma who receive RVD induction0.00Citations (PDF)
322Bone Turnover Biomarkers Are Useful In Monitoring Myeloma Bone Disease and As Early Predictor Biomarkers For Relapse Disease In Multiple Myeloma
Blood, 2013, 122, 1869-1869
4.22Citations (PDF)
323MM-005: A Phase 1 Trial Of Pomalidomide, Bortezomib, and Low-Dose Dexamethasone (PVD) In Relapsed and/Or Refractory Multiple Myeloma (RRMM)
Blood, 2013, 122, 1969-1969
4.212Citations (PDF)
324Time To Event Analyses in PANORAMA 2: A Phase 2 Study Of Panobinostat, Bortezomib, and Dexamethasone In Patients With Relapsed and Bortezomib-Refractory Multiple Myeloma
Blood, 2013, 122, 1970-1970
4.24Citations (PDF)
325A Phase I/II Open-Label Multicenter Study Of The Cyclin Kinase Inhibitor AT7519M Alone and In Combination With Bortezomib In Patients With Previously Treated Multiple Myeloma
Blood, 2013, 122, 1976-1976
4.215Citations (PDF)
326Phase I/II Trial Of Everolimus, Bortezomib and Rituximab In Relapsed Or Relapsed/Refractory Waldenstrom's Macroglobulinemia
Blood, 2013, 122, 4402-4402
4.25Citations (PDF)
327Twice-Weekly Oral MLN9708 (Ixazomib Citrate), An Investigational Proteasome Inhibitor, In Combination With Lenalidomide (Len) and Dexamethasone (Dex) In Patients (Pts) With Newly Diagnosed Multiple Myeloma (MM): Final Phase 1 Results and Phase 2 Data
Blood, 2013, 122, 535-535
4.220Citations (PDF)
328ACY-1215, a Selective Histone Deacetylase (HDAC) 6 Inhibitor: Interim Results Of Combination Therapy With Bortezomib In Patients With Multiple Myeloma (MM)
Blood, 2013, 122, 759-759
4.219Citations (PDF)
329New Insights into the Treatment of Multiple Myeloma with Histone Deacetylase Inhibitors2.41Citations (PDF)
330Antitumor Activities Of An Oral Selective HSP90α/β Inhibitor, TAS-116, In Combination With Bortezomib In Multiple Myeloma
Blood, 2013, 122, 4429-4429
4.20Citations (PDF)
331High Risk Multiple Myeloma Cases Are Identified In An MMRC Led Study By The SKY92 Gene Signature (MMprofiler)
Blood, 2013, 122, 1854-1854
4.20Citations (PDF)
332Proton Pump Inhibitors
Drugs, 2012, 56, 307-335
11.8121Citations (PDF)
333Proteasome Inhibition
American Journal of Cancer, 2012, 3, 271-279
0.10Citations (PDF)
334Management Strategies for Relapsed Multiple Myeloma
American Journal of Cancer, 2012, 5, 393-409
0.11Citations (PDF)
335Emerging Therapies for Multiple Myeloma
American Journal of Cancer, 2012, 5, 141-153
0.11Citations (PDF)
336Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma
Clinical Cancer Research, 2012, 18, 4669-4681
6.980Citations (PDF)
337Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
Blood, 2012, 119, 4375-4382
4.2431Citations (PDF)
338Molecular and Cellular Effects of NEDD8-Activating Enzyme Inhibition in Myeloma1.852Citations (PDF)
339Safety and efficacy of defibrotide for the treatment of severe hepatic veno-occlusive disease3.042Citations (PDF)
340Compartment-specific bioluminescence imaging platform for the high-throughput evaluation of antitumor immune function
Blood, 2012, 119, e131-e138
4.229Citations (PDF)
341IMWG consensus on maintenance therapy in multiple myeloma
Blood, 2012, 119, 3003-3015
4.2181Citations (PDF)
342A review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomide
Blood, 2012, 119, 2764-2767
4.2147Citations (PDF)
343Investigational agent MLN9708/2238 targets tumor-suppressor miR33b in MM cells
Blood, 2012, 120, 3958-3967
4.273Citations (PDF)
344How I treat plasma cell leukemia
Blood, 2012, 120, 2376-2389
4.2130Citations (PDF)
345Sequence analysis of β-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone
Blood, 2012, 120, 4513-4516
4.277Citations (PDF)
346Methyljasmonate displays <i>in vitro</i> and <i>in vivo</i> activity against multiple myeloma cells
British Journal of Haematology, 2012, 159, 340-351
2.428Citations (PDF)
347Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
Blood, 2012, 119, 5772-5781
4.2392Citations (PDF)
348A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance
Cancer Cell, 2012, 22, 345-358
38.5565Citations (PDF)
349Perifosine, an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity2.8104Citations (PDF)
350Management of myeloma-associated renal dysfunction in the era of novel therapies2.031Citations (PDF)
351Defibrotide for the treatment of hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation
Expert Review of Hematology, 2012, 5, 291-302
2.047Citations (PDF)
352Latest advances and current challenges in the treatment of multiple myeloma75.5197Citations (PDF)
353New Proteasome Inhibitors in Myeloma2.890Citations (PDF)
354Proteasome inhibitors in multiple myeloma: 10 years later
Blood, 2012, 120, 947-959
4.2475Citations (PDF)
355Lenalidomide for the treatment of relapsed and refractory multiple myeloma2.029Citations (PDF)
356Imaging Features of Extramedullary, Relapsed, and Refractory Multiple Myeloma involving the Liver Across Treatment With Cyclophosphamide, Lenalidomide, Bortezomib, and Dexamethasone
Journal of Clinical Oncology, 2012, 30, e175-e179
21.610Citations (PDF)
357Lenalidomide after Stem-Cell Transplantation for Multiple Myeloma
New England Journal of Medicine, 2012, 366, 1770-1781
43.71,091Citations (PDF)
358Pathological crystallization of human immunoglobulins7.638Citations (PDF)
359The Medical Research Council Myeloma IX trial: the impact on treatment paradigms*1.97Citations (PDF)
360The potential benefits of participating in early‐phase clinical trials in multiple myeloma: long‐term remission in a patient with relapsed multiple myeloma treated with 90 cycles of lenalidomide and bortezomib1.911Citations (PDF)
361Perifosine plus lenalidomide and dexamethasone in relapsed and relapsed/refractory multiple myeloma: a Phase I Multiple Myeloma Research Consortium study
British Journal of Haematology, 2012, 158, 472-480
2.456Citations (PDF)
362PANORAMA 2: Panobinostat Combined with Bortezomib and Dexamethasone in Patients with Relapsed and Bortezomib-Refractory Multiple Myeloma
Blood, 2012, 120, 1852-1852
4.27Citations (PDF)
363A Phase 2 Study of Elotuzumab (Elo) in Combination with Lenalidomide and Low-Dose Dexamethasone (Ld) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (R/R MM): Updated Results
Blood, 2012, 120, 202-202
4.218Citations (PDF)
364Early Changes in Cytokines, Chemokines and Indices of Bone Metabolism in a Phase 2 Study of the Bruton Tyrosine Kinase (Btk) Inhibitor, Ibrutinib (PCI-32765) in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM)
Blood, 2012, 120, 4039-4039
4.23Citations (PDF)
365Improvement in Clinical Benefit Parameters with Pomalidomide (POM) in Combination with Low-Dose Dexamethasone (LoDEX) in Patients with Relapsed and Refractory Multiple Myeloma (RRMM): Results From a Phase 2 Study
Blood, 2012, 120, 4052-4052
4.22Citations (PDF)
366Treatment Outcomes with Pomalidomide (POM) in Combination with Low-Dose Dexamethasone (LoDex) in Patients with Relapsed and Refractory Multiple Myeloma (RRMM) and Del(17p13) and/or t(4;14)(p16;q32) Cytogenetic Abnormalities Who Have Received Prior Therapy with Lenalidomide (LEN) and Bortezomib (BORT)
Blood, 2012, 120, 4053-4053
4.24Citations (PDF)
367Pomalidomide (POM) with Low-Dose Dexamethasone (LoDEX) in Patients with Relapsed and Refractory Multiple Myeloma (RRMM): Outcomes Based on Prior Treatment Exposure
Blood, 2012, 120, 4070-4070
4.21Citations (PDF)
368Pomalidomide (POM) with Low-Dose Dexamethasone (LoDEX) in Patients with Relapsed and Refractory Multiple Myeloma (RRMM): Impact of Renal Function on Patient Outcomes
Blood, 2012, 120, 4072-4072
4.25Citations (PDF)
369Pomalidomide (POM) with Low-Dose Dexamethasone (LoDex) in Patients (Pts) with Relapsed and Refractory Multiple Myeloma Who Have Received Prior Therapy with Lenalidomide (LEN) and Bortezomib (BORT): Updated Phase 2 Results and Age Subgroup Analysis
Blood, 2012, 120, 450-450
4.211Citations (PDF)
370Daratumumab, a CD38 Monoclonal Antibody in Patients with Multiple Myeloma - Data From a Dose-Escalation Phase I/II Study
Blood, 2012, 120, 73-73
4.262Citations (PDF)
371Reprogramming Aberrant B Cell-Subsets to Improve Immune Function in Multiple Myeloma
Blood, 2012, 120, 3986-3986
4.212Citations (PDF)
372Myeloid Derived Suppressor Cells (MDSCs) Regulate Tumor Growth, Immune Response and Regulatory T Cell (Treg) Development in the Multiple Myeloma Bone Marrow Microenvironment
Blood, 2012, 120, 565-565
4.22Citations (PDF)
373Targeting Aminopeptidases by Tosedostat (TST) (CHR2797), Alone and with LBH589, Induces Significant Cytotoxicity Against Human Multiple Myeloma (MM) Cells
Blood, 2012, 120, 1847-1847
4.20Citations (PDF)
374Formation of the Functional Niche in Vitro by Mimicking the Pathophysiological Features of the Bone Marrow Microenvironment in Multiple Myeloma
Blood, 2012, 120, 1812-1812
4.20Citations (PDF)
375Cells of the Osteoblast Lineage Confer Myeloma Cell Resistance to Established and Investigational Therapeutic Agents
Blood, 2012, 120, 3995-3995
4.20Citations (PDF)
376<i>In Vitro</i> and <i>In Vivo</i> Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 against Multiple Myeloma Cells
Clinical Cancer Research, 2011, 17, 5311-5321
6.9300Citations (PDF)
377Multiple Myeloma
Annual Review of Medicine, 2011, 62, 249-264
19.5139Citations (PDF)
378Future Directions of Next-Generation Novel Therapies, Combination Approaches, and the Development of Personalized Medicine in Myeloma
Journal of Clinical Oncology, 2011, 29, 1916-1923
21.680Citations (PDF)
379Thalidomide, lenalidomide and bortezomib in the management of newly diagnosed multiple myeloma2.023Citations (PDF)
380BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Cell, 2011, 146, 904-917
34.12,665Citations (PDF)
381Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study
Lancet Oncology, The, 2011, 12, 263-272
26.094Citations (PDF)
382Vaccination with dendritic cell/tumor fusion cells results in cellular and humoral antitumor immune responses in patients with multiple myeloma
Blood, 2011, 117, 393-402
4.2213Citations (PDF)
383Genetic variation associated with bortezomib-induced peripheral neuropathy1.364Citations (PDF)
384Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications
Blood, 2011, 117, 4409-4419
4.2150Citations (PDF)
385Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1
Blood, 2011, 117, 4691-4695
4.2953Citations (PDF)
386International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation
Blood, 2011, 117, 6063-6073
4.2295Citations (PDF)
387Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Research Consortium trial
Blood, 2011, 118, 535-543
4.284Citations (PDF)
388Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy
Haematologica, 2011, 96, 1662-1669
4.162Citations (PDF)
389Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers
British Journal of Haematology, 2011, 152, 367-379
2.4123Citations (PDF)
390Molecular and cellular effects of multi‐targeted cyclin‐dependent kinase inhibition in myeloma: biological and clinical implications
British Journal of Haematology, 2011, 152, 420-432
2.424Citations (PDF)
391Characterization of haematological parameters with bortezomib–melphalan–prednisone <i>versus</i> melphalan–prednisone in newly diagnosed myeloma, with evaluation of long‐term outcomes and risk of thromboembolic events with use of erythropoiesis‐stimulating agents: analysis of the VISTA trial
British Journal of Haematology, 2011, 153, 212-221
2.414Citations (PDF)
392Tanespimycin and bortezomib combination treatment in patients with relapsed or relapsed and refractory multiple myeloma: results of a phase 1/2 study
British Journal of Haematology, 2011, 153, 729-740
2.4103Citations (PDF)
393Monoclonal antibodies in the treatment of multiple myeloma
British Journal of Haematology, 2011, 154, 745-754
2.470Citations (PDF)
394Managing multiple myeloma: the emerging role of novel therapies and adapting combination treatment for higher risk settings
British Journal of Haematology, 2011, 154, 755-762
2.420Citations (PDF)
395Risk factors for, and reversibility of, peripheral neuropathy associated with bortezomib-melphalan-prednisone in newly diagnosed patients with multiple myeloma: subanalysis of the phase 3 VISTA study1.9136Citations (PDF)
396A novel panel of protein biomarkers for predicting response to thalidomide‐based therapy in newly diagnosed multiple myeloma patients
Proteomics, 2011, 11, 1391-1402
3.134Citations (PDF)
397A phase I safety study of enzastaurin plus bortezomib in the treatment of relapsed or refractory multiple myeloma6.121Citations (PDF)
398Mechanism of Action of Proteasome Inhibitors and Deacetylase Inhibitors and the Biological Basis of Synergy in Multiple Myeloma
Molecular Cancer Therapeutics, 2011, 10, 2034-2042
1.8260Citations (PDF)
399Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma
Haematologica, 2011, 96, 1170-1179
4.175Citations (PDF)
400Treatment Options for Relapsed and Refractory Multiple Myeloma
Clinical Cancer Research, 2011, 17, 1264-1277
6.9119Citations (PDF)
401A phase 1 study of IPI-504 (retaspimycin hydrochloride) in patients with relapsed or relapsed and refractory multiple myeloma
Leukemia and Lymphoma, 2011, 52, 2308-2315
1.528Citations (PDF)
402Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: A multicenter international myeloma working group study
Leukemia, 2011, 26, 149-157
10.4708Citations (PDF)
403Blockade of XBP1 Splicing by Inhibition of IRE1α Is a Promising Therapeutic Option in Multiple Myeloma
Blood, 2011, 118, 133-133
4.22Citations (PDF)
404A Phase I/II, Dose-Escalation Study of Daratumumab, A CD38 Mab in Patients with Multiple Myeloma – Preliminary Safety Data
Blood, 2011, 118, 1873-1873
4.22Citations (PDF)
405Phase I Trial of Plerixafor and Bortezomib As a Chemosensitization Strategy in Relapsed or Relapsed/Refractory Multiple Myeloma
Blood, 2011, 118, 1874-1874
4.21Citations (PDF)
406Simulation of Clinical Outcome for Pomalidomide Plus Low-Dose Dexamethasone in Patients with Refractory Multiple Myeloma Based on Week 8 M-Protein Response
Blood, 2011, 118, 1881-1881
4.211Citations (PDF)
407Phase I Trial of Everolimus and Rituximab or Everolimus, Bortezomib and Rituximab in Relapsed or Relapsed/Refractory Waldenstrom's Macroglobulinemia
Blood, 2011, 118, 2705-2705
4.21Citations (PDF)
408Final Results of the Phase II Trial of Single Agent Panobinostat (LBH589) in Relapsed or Relapsed/Refractory Waldenstrom Macroglobulinemia
Blood, 2011, 118, 2706-2706
4.21Citations (PDF)
409Risk of Second Primary Malignancies (SPMs) Following Bortezomib (Btz)-Based Therapy: Analysis of Four Phase 3 Randomized Controlled Trials in Previously Untreated or Relapsed Multiple Myeloma (MM)
Blood, 2011, 118, 2933-2933
4.25Citations (PDF)
410Investigational Agent MLN9708, An Oral Proteasome Inhibitor, in Patients (Pts) with Relapsed and/or Refractory Multiple Myeloma (MM): Results From the Expansion Cohorts of a Phase 1 Dose-Escalation Study
Blood, 2011, 118, 301-301
4.210Citations (PDF)
411Phase 1 Clinical Evaluation of Twice-Weekly Marizomib (NPI-0052), a Novel Proteasome Inhibitor, in Patients with Relapsed/Refractory Multiple Myeloma (MM)
Blood, 2011, 118, 302-302
4.230Citations (PDF)
412A Phase 2 Study of Elotuzumab in Combination with Lenalidomide and Low-Dose Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma
Blood, 2011, 118, 303-303
4.28Citations (PDF)
413Biomarker Correlation with Outcomes in Patients with Relapsed or Refractory Multiple Myeloma on a Phase I Study of Everolimus in Combination with Lenalidomide,
Blood, 2011, 118, 3966-3966
4.22Citations (PDF)
414Elotuzumab in Combination with Lenalidomide and Low-Dose Dexamethasone in High-Risk and/or Stage 23 Relapsed and/or Refractory Multiple Myeloma: A Retrospective Subset Analysis of the Phase 2 Study,
Blood, 2011, 118, 3968-3968
4.21Citations (PDF)
415Continued Overall Survival Benefit After 5 Years' Follow-up with Bortezomib-Melphalan-Prednisone (VMP) Versus Melphalan-Prednisone (MP) in Patients with Previously Untreated Multiple Myeloma, and No Increased Risk of Second Primary Malignancies: Final Results of the Phase 3 VISTA Trial
Blood, 2011, 118, 476-476
4.218Citations (PDF)
416Phase 1/2 Study of Oral MLN9708, A Novel, Investigational Proteasome Inhibitor, in Combination with Lenalidomide and Dexamethasone in Patients with Previously Untreated Multiple Myeloma (MM)
Blood, 2011, 118, 479-479
4.25Citations (PDF)
417Defibrotide (DF) in the Treatment of Hepatic Veno-Occlusive Disease (VOD) in Stem Cell Transplant (SCT) and Non-SCT Patients (Pts): Early Intervention Improves Outcome - Updated Results of a Treatment IND Expanded Access Protocol
Blood, 2011, 118, 487-487
4.23Citations (PDF)
418Randomized, Open Label Phase 1/2 Study of Pomalidomide (POM) Alone or in Combination with Low-Dose Dexamethasone (LoDex) in Patients (Pts) with Relapsed and Refractory Multiple Myeloma Who Have Received Prior Treatment That Includes Lenalidomide (LEN) and Bortezomib (BORT): Phase 2 Results
Blood, 2011, 118, 634-634
4.211Citations (PDF)
419Inhibition of c-Myc Expression and Function in Hematologic Malignancies
Blood, 2011, 118, 1409-1409
4.20Citations (PDF)
420Perifosine Plus Bortezomib and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients Previously Treated with Bortezomib: Final Results of a Phase I/II Trial
Blood, 2011, 118, 815-815
4.20Citations (PDF)
421RVD Induction Followed by Consolidation with ASCT in Patients with Newly Diagnosed Multiple Myeloma,
Blood, 2011, 118, 4134-4134
4.20Citations (PDF)
422Mitochondrial Apoptotic Priming Measured by BH3 Profiling Regulates Clinical Response to Chemotherapy in Myeloma and Acute Lymphoblastic Leukemia and Explains Therapeutic Index
Blood, 2011, 118, 1442-1442
4.20Citations (PDF)
423Mutational Analysis of Tumor Samples From Patients with Relapsed or Refractory Multiple Myeloma (MM) Highlights the Prevalence of RAS/RAF Pathway Activation and Demonstrates Previously Unreported Mutations in Known Cancer Genes
Blood, 2011, 118, 1377-1377
4.20Citations (PDF)
424A Novel Acanthoic Acid Analog NPI-1342 Blocks IκB Kinase-α and Trigger In Vitro and In Vivo cytotoxicity in Multiple Myeloma Cells
Blood, 2011, 118, 1841-1841
4.20Citations (PDF)
425Differences in Patterns of Treatment and Outcome Among Patients with Relapsed Refractory Myeloma From United States, Europe and Asia,
Blood, 2011, 118, 3989-3989
4.20Citations (PDF)
426Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing
Blood, 2011, 118, 1838-1838
4.25Citations (PDF)
427PI3K/p110δ is a novel therapeutic target in multiple myeloma
Blood, 2010, 116, 1460-1468
4.2185Citations (PDF)
428A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
Blood, 2010, 115, 5202-5213
4.2267Citations (PDF)
429Kidney disease associated with plasma cell dyscrasias
Blood, 2010, 116, 1397-1404
4.253Citations (PDF)
430Superior outcomes associated with complete response in newly diagnosed multiple myeloma patients treated with nonintensive therapy: analysis of the phase 3 VISTA study of bortezomib plus melphalan-prednisone versus melphalan-prednisone
Blood, 2010, 116, 3743-3750
4.2102Citations (PDF)
431A novel orally active proteasome inhibitor ONX 0912 triggers in vitro and in vivo cytotoxicity in multiple myeloma
Blood, 2010, 116, 4906-4915
4.2196Citations (PDF)
432Improving the therapeutic index in myeloma
Blood, 2010, 116, 4733-4734
4.24Citations (PDF)
433Combination of novel proteasome inhibitor NPI-0052 and lenalidomide trigger in vitro and in vivo synergistic cytotoxicity in multiple myeloma
Blood, 2010, 115, 834-845
4.2107Citations (PDF)
434Complications of Multiple Myeloma Therapy, Part 1: Risk Reduction and Management of Peripheral Neuropathy and Asthenia12.939Citations (PDF)
435Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma
Blood, 2010, 116, 3227-3237
4.2215Citations (PDF)
436The evolution and impact of therapy in multiple myeloma
Medical Oncology, 2010, 27, 1-6
2.434Citations (PDF)
437Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti‐myeloma activity <i>in vitro</i> and <i>in vivo</i>
British Journal of Haematology, 2010, 149, 537-549
2.4124Citations (PDF)
438Tanespimycin with bortezomib: activity in relapsed/refractory patients with multiple myeloma
British Journal of Haematology, 2010, 150, 428-437
2.472Citations (PDF)
439Tanespimycin monotherapy in relapsed multiple myeloma: results of a phase 1 dose‐escalation study
British Journal of Haematology, 2010, 150, 438-445
2.474Citations (PDF)
440THE TREATMENT OF MULTIPLE MYELOMA PATIENTS NOT ELIGIBLE FOR ASCT0.82Citations (PDF)
441Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
Blood, 2010, 116, 679-686
4.2838Citations (PDF)
442Phase II Clinical and Pharmacokinetic Study of Plitidepsin 3-Hour Infusion Every Two Weeks Alone or with Dexamethasone in Relapsed and Refractory Multiple Myeloma
Clinical Cancer Research, 2010, 16, 3260-3269
6.972Citations (PDF)
443Melphalan, prednisone, thalidomide and defibrotide in relapsed/refractory multiple myeloma: results of a multicenter phase I/II trial
Haematologica, 2010, 95, 1144-1149
4.139Citations (PDF)
444Conflicts of Interest, Authorship, and Disclosures in Industry-Related Scientific Publications–2
Mayo Clinic Proceedings, 2010, 85, 197-199
3.15Citations (PDF)
445Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group
Journal of Clinical Oncology, 2010, 28, 4976-4984
21.6384Citations (PDF)
446Hepatic Veno-Occlusive Disease following Stem Cell Transplantation: Incidence, Clinical Course, and Outcome1.6573Citations (PDF)
447Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease and Multiorgan Failure after Stem Cell Transplantation: A Multicenter, Randomized, Dose-Finding Trial1.6232Citations (PDF)
448Prediction of Veno-Occlusive Disease Using Biomarkers of Endothelial Injury1.693Citations (PDF)
449Towards a better understanding of treatment-related peripheral neuropathy in multiple myeloma
Lancet Oncology, The, 2010, 11, 1014-1016
26.07Citations (PDF)
450Phase I Trial of Plerixafor and Bortezomib as a Chemosensitization Strategy In Relapsed or Relapsed/Refractory Multiple Myeloma
Blood, 2010, 116, 1943-1943
4.22Citations (PDF)
451A Phase I Study of Vorinostat, Lenalidomide, and Dexamethasone In Patients with Relapsed or Relapsed and Refractory Multiple Myeloma: Excellent Tolerability and Promising Activity In a Heavily Pretreated Population
Blood, 2010, 116, 1951-1951
4.217Citations (PDF)
452A Novel SIRT1 Activator SIRT1720 Triggers In Vitro and In Vivo Cytotoxicity In Multiple Myeloma Via ATM-Dependent Mechanism
Blood, 2010, 116, 3007-3007
4.21Citations (PDF)
453Daratumumab Directly Induces Human Multiple Myeloma Cell Death and Acts Synergistically with Conventional and Novel Anti-Myeloma Drugs
Blood, 2010, 116, 3013-3013
4.213Citations (PDF)
454Updated Results of a Phase I Study of RAD001 In Combination with Lenalidomide In Patients with Relapsed or Refractory Multiple Myeloma with Pharmacodynamic and Pharmacokinetic Analysis
Blood, 2010, 116, 3051-3051
4.24Citations (PDF)
455Meta-Analysis of Defibrotide (DF) In the Treatment of Severe Hepatic Veno-Occlusive Disease (VOD) with Multi-Organ Failure (MOF) with Comparison to a Historical Control (HC).
Blood, 2010, 116, 3481-3481
4.25Citations (PDF)
456Safety of Defibrotide (DF) In Stem Cell Transplant (SCT) Patients (Pts).
Blood, 2010, 116, 3482-3482
4.23Citations (PDF)
457Phase II Trial of Single Agent Panobinostat (LBH589) In Relapsed or Relapsed/Refractory Waldenstrom Macroglobulinemia
Blood, 2010, 116, 3952-3952
4.29Citations (PDF)
458Novel Three- and Four-Drug Combination Regimens of Bortezomib, Dexamethasone, Cyclophosphamide, and Lenalidomide, for Previously Untreated Multiple Myeloma: Results From the Multi-Center, Randomized, Phase 2 EVOLUTION Study
Blood, 2010, 116, 621-621
4.215Citations (PDF)
459Defibrotide (DF) In the Treatment of Severe Hepatic Veno-Occlusive Disease (VOD) with Multi-Organ Failure (MOF): Results of a Treatment IND Expanded Access Protocol
Blood, 2010, 116, 906-906
4.23Citations (PDF)
460Elotuzumab In Combination with Lenalidomide and Dexamethasone In Patients with Relapsed Multiple Myeloma: Interim Results of a Phase 2 Study
Blood, 2010, 116, 986-986
4.26Citations (PDF)
461Final Results of the Phase I/II Trial of Weekly Bortezomib In Combination with Temsirolimus (CCI-779) In Relapsed or Relapsed/Refractory Multiple Myeloma Specifically In Patients Refractory to Bortezomib
Blood, 2010, 116, 990-990
4.25Citations (PDF)
462Proteomic Profiling of Multiple Myeloma (MM) Cells Using iTRAQ and Label-Free Quantitative Proteomics for the Prediction of Complete or near Complete Response (CR/nCR) In Frontline Treatment with Lenalidomide, Bortezomib, and Dexamethasone
Blood, 2010, 116, 618-618
4.20Citations (PDF)
463MLN4924, a Novel Investigational NEDD8 Activating Enzyme Inhibitor, Exhibits Preclinical Activity In Multiple Myeloma and Waldenström's Macroglobulinemia through Mechanism Distinct From Existing Proteasome Inhibitors
Blood, 2010, 116, 2988-2988
4.22Citations (PDF)
464An Investigational Novel Orally Bioavailable Proteasome Inhibitor MLN9708/MLN2238 Triggers Cytotoxicity In Multiple Myeloma Cells Via p21- and Caspase-8-Dependent Signaling Pathway
Blood, 2010, 116, 2992-2992
4.20Citations (PDF)
465Human Monoclonal Antibody Targeting IL-17A (AIN457) Down-Regulates MM Cell-Growth and Survival and Inhibits Osteoclast Development In Vitro and In Vivo: A Potential Novel Therapeutic Application In Myeloma
Blood, 2010, 116, 456-456
4.27Citations (PDF)
466Hematological Testing Is Not Required with Every Dose of Bortezomib In Patients with Adequate Blood Counts at the Start of Each Cycle
Blood, 2010, 116, 1963-1963
4.21Citations (PDF)
467Preclinical Studies of Salinomycin In Multiple Myeloma (MM) Models: Targeting of Side Population (SP) Cells In the Context of Tumor – Microenvironment Interactions.
Blood, 2010, 116, 1574-1574
4.228Citations (PDF)
468Compartment-Specific Bioluminescence Imaging Platform for the Open-Ended Identification of Novel Immunomodulatory Agents and High-Throughput Evaluation of Anti-Tumor Immune Function
Blood, 2010, 116, 451-451
4.20Citations (PDF)
469Lenalidomide Enhances Multiple Myeloma Cytotoxicity Induced by a Novel Fc Domain-Engineered Anti-HM1.24 Monoclonal Antibody with Augmented NK Cell Degranulation
Blood, 2010, 116, 4064-4064
4.20Citations (PDF)
470Elotuzumab In Combination with Bortezomib In Patients with Relapsed/Refractory Multiple Myeloma: Updated Results of a Phase 1 Study
Blood, 2010, 116, 3023-3023
4.29Citations (PDF)
471Synergistic Enhancement of Conventional Anti-MM Drugs Efficacy with Plant Isothiocyanates: Therapeutic Implications
Blood, 2010, 116, 5016-5016
4.20Citations (PDF)
472Bortezomib in the management of multiple myeloma
Cancer Management and Research, 2009, Volume 1, 107-117
2.09Citations (PDF)
473Novel Therapies in the Treatment of Multiple Myeloma12.938Citations (PDF)
474Clinical challenges associated with bortezomib therapy in multiple myeloma and Waldenströms Macroglobulinemia
Leukemia and Lymphoma, 2009, 50, 694-702
1.533Citations (PDF)
475Use of defibrotide in the treatment and prevention of veno-occlusive disease
Expert Review of Hematology, 2009, 2, 365-376
2.015Citations (PDF)
476Interactions of the Hdm2/p53 and Proteasome Pathways May Enhance the Antitumor Activity of Bortezomib
Clinical Cancer Research, 2009, 15, 7153-7160
6.967Citations (PDF)
477Emerging therapies for multiple myeloma2.452Citations (PDF)
478Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
Blood, 2009, 114, 1046-1052
4.2352Citations (PDF)
479Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target
Cancer Cell, 2009, 16, 309-323
38.5266Citations (PDF)
480Reversibility of symptomatic peripheral neuropathy with bortezomib in the phase III APEX trial in relapsed multiple myeloma: impact of a dose‐modification guideline
British Journal of Haematology, 2009, 144, 895-903
2.4297Citations (PDF)
481Expanded safety experience with lenalidomide plus dexamethasone in relapsed or refractory multiple myeloma
British Journal of Haematology, 2009, 146, 164-170
2.480Citations (PDF)
482Impact of prior therapies on the relative efficacy of bortezomib compared with dexamethasone in patients with relapsed/refractory multiple myeloma
British Journal of Haematology, 2009, 147, 531-534
2.428Citations (PDF)
483<i>In vitro</i> anti‐myeloma activity of the Aurora kinase inhibitor VE‐465
British Journal of Haematology, 2009, 147, 672-676
2.427Citations (PDF)
484Emerging Treatments for Multiple Myeloma: Beyond Immunomodulatory Drugs and Bortezomib
Seminars in Hematology, 2009, 46, 166-175
3.254Citations (PDF)
485Multiple myeloma
Lancet, The, 2009, 374, 324-339
52.8728Citations (PDF)
486The fibrinolytic mechanism of defibrotide: effect of defibrotide on plasmin activity1.040Citations (PDF)
487Biologic sequelae of IκB kinase (IKK) inhibition in multiple myeloma: therapeutic implications
Blood, 2009, 113, 5228-5236
4.270Citations (PDF)
488Safety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myeloma
Blood, 2009, 114, 772-778
4.2149Citations (PDF)
489How I treat multiple myeloma in younger patients
Blood, 2009, 114, 5436-5443
4.2124Citations (PDF)
490Novel Three– and Four–Drug Combinations of Bortezomib, Dexamethasone, Cyclophosphamide, and Lenalidomide, for Newly Diagnosed Multiple Myeloma: Encouraging Results From the Multi-Center, Randomized, Phase 2 EVOLUTION Study.
Blood, 2009, 114, 127-127
4.219Citations (PDF)
491Lenalidomide, Bortezomib, Pegylated Liposomal Doxorubicin, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Updated Results of Phase I/II MMRC Trial.
Blood, 2009, 114, 132-132
4.27Citations (PDF)
492Lack of Response to Vaccination in MGUS and Stable Myeloma.
Blood, 2009, 114, 1852-1852
4.211Citations (PDF)
493Tanespimycin + Bortezomib in Relapsed/Refractory Myeloma Patients: Results From the Time-2 Study.
Blood, 2009, 114, 1871-1871
4.24Citations (PDF)
494Natural History of Multiple Myeloma Relapsing After Therapy with IMiDs and Bortezomib: A Multicenter International Myeloma Working Group Study.
Blood, 2009, 114, 2878-2878
4.218Citations (PDF)
495Tanespimycin + Bortezomib Demonstrates Safety, Activity, and Effective Target Inhibition in Relapsed/Refractory Myeloma Patients: Updated Results of a Phase 1/2 Study.
Blood, 2009, 114, 2890-2890
4.27Citations (PDF)
496Defibrotide (DF) in the Treatment of Severe Hepatic Veno-Occlusive Disease (VOD) with Multi-Organ Failure (MOF) Following Stem Cell Transplantation (SCT): Results of a Phase 3 Study Utilizing a Historical Control.
Blood, 2009, 114, 654-654
4.213Citations (PDF)
497Lenalidomide in multiple myeloma: an evidence-based review of its role in therapy
Core Evidence, 2009, , 215
2.019Citations (PDF)
498Immunomodulatory EFFECTS of Lenalidomide and Pomalidomide ON INTERACTION of TUMOR and BONE MARROW Accessory CELLS IN MULTIPLE MYELOMA.
Blood, 2009, 114, 950-950
4.20Citations (PDF)
499Whole Genome Paired End Sequencing Identifies Genomic Evolution in Myeloma.
Blood, 2009, 114, 2846-2846
4.23Citations (PDF)
500A NOVEL Aurora A Kinase INHIBITOR MLN8237 Induces Cytotoxicity and CELL Cycle Arrest IN MULTIPLE MYELOMA.
Blood, 2009, 114, 3830-3830
4.21Citations (PDF)
501PR-924, a Selective Inhibitor of the Immunoproteasome Subunit LMP-7 Blocks Multiple Myeloma Cell Growth Both in Vitro and In Vivo.
Blood, 2009, 114, 612-612
4.20Citations (PDF)
502The relationship between quality of response and clinical benefit for patients treated on the bortezomib arm of the international, randomized, phase 3 APEX trial in relapsed multiple myeloma2.495Citations (PDF)
503Characterisation of haematological profiles and low risk of thromboembolic events with bortezomib in patients with relapsed multiple myeloma
British Journal of Haematology, 2008, 143, 222-229
2.495Citations (PDF)
504Updated survival analyses after prolonged follow‐up of the phase 2, multicenter CREST study of bortezomib in relapsed or refractory multiple myeloma
British Journal of Haematology, 2008, 143, 537-540
2.490Citations (PDF)
505Bortezomib is associated with better health‐related quality of life than high‐dose dexamethasone in patients with relapsed multiple myeloma: results from the APEX study
British Journal of Haematology, 2008, 143, 511-519
2.458Citations (PDF)
506Bortezomib plus Melphalan and Prednisone for Initial Treatment of Multiple Myeloma43.71,839Citations (PDF)
507Bortezomib in the front-line treatment of multiple myeloma2.681Citations (PDF)
508Phase I trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) in patients with advanced multiple myeloma
Leukemia and Lymphoma, 2008, 49, 502-507
1.5187Citations (PDF)
509Re: When You Look Matters: The Effect of Assessment Schedule on Progression-Free Survival4.77Citations (PDF)
510Phase I, Pharmacokinetic and Pharmacodynamic Study of the Anti–Insulinlike Growth Factor Type 1 Receptor Monoclonal Antibody CP-751,871 in Patients With Multiple Myeloma
Journal of Clinical Oncology, 2008, 26, 3196-3203
21.6158Citations (PDF)
511Analysis of Herpes Zoster Events Among Bortezomib-Treated Patients in the Phase III APEX Study
Journal of Clinical Oncology, 2008, 26, 4784-4790
21.6257Citations (PDF)
512Combination of proteasome inhibitors bortezomib and NPI-0052 trigger in vivo synergistic cytotoxicity in multiple myeloma
Blood, 2008, 111, 1654-1664
4.2195Citations (PDF)
513Anti-CS1 humanized monoclonal antibody HuLuc63 inhibits myeloma cell adhesion and induces antibody-dependent cellular cytotoxicity in the bone marrow milieu
Blood, 2008, 112, 1329-1337
4.2463Citations (PDF)
514Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease
Blood, 2008, 112, 4343-4352
4.260Citations (PDF)
515Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation
Blood, 2008, 112, 4425-4431
4.2156Citations (PDF)
516Advances in the treatment of monoclonal gammopaties: The emerging role of targeted therapy in plasma cell dyscrasias2.03Citations (PDF)
517The monoclonal antibody nBT062 conjugated to maytansinoids has potent and selective cytotoxicity against CD138 positive multiple myeloma cells in vitro and in vivo0.12Citations (PDF)
518A review of lenalidomide in combination with dexamethasone for the treatment of multiple myeloma2.135Citations (PDF)
519Phase II Trial of the mTOR Inhibitor RAD001 in Relapsed and/or Refractory Waldenstrom Macroglobulinemia: The Dana Farber Cancer Institute Experience.
Blood, 2008, 112, 1011-1011
4.21Citations (PDF)
520A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.
Blood, 2008, 112, 1719-1719
4.22Citations (PDF)
521Combination of a Novel Proteasome Inhibitor NPI-0052 and Lenalidomide Trigger in Vivo Synergistic Cytotoxicity in Multiple Myeloma
Blood, 2008, 112, 3662-3662
4.23Citations (PDF)
522Phase I Results of Perifosine (KRX-0401) in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed or Refractory Multiple Myeloma (MM)
Blood, 2008, 112, 3691-3691
4.212Citations (PDF)
523Phase I Trial of CCI-779 (Temsirolimus) and Weekly Bortezomib in Relapsed and/or Refractory Multiple Myeloma
Blood, 2008, 112, 3696-3696
4.226Citations (PDF)
524Final Results of a Phase II Trial with Plitidepsin (Aplidin) Alone and in Combination with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma
Blood, 2008, 112, 3700-3700
4.27Citations (PDF)
525Phase II Trial of Combination of Bortezomib and Rituximab in Relapsed and/or Refractory Waldenstrom Macroglobulinemia
Blood, 2008, 112, 832-832
4.27Citations (PDF)
526Lenalidomide, Bortezomib, and Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma: Encouraging Efficacy in High Risk Groups with Updated Results of a Phase I/II Study
Blood, 2008, 112, 92-92
4.234Citations (PDF)
527Safety and Efficacy of Novel Combination Therapy with Bortezomib, Dexamethasone, Cyclophosphamide, and Lenalidomide in Newly Diagnosed Multiple Myeloma: Initial Results from the Phase I/II Multi-Center EVOLUTION Study
Blood, 2008, 112, 93-93
4.217Citations (PDF)
528Sulforaphane and PEITC Augment Activity of Conventional and Novel Anti-Myeloma Drugs
Blood, 2008, 112, 2648-2648
4.211Citations (PDF)
529Immunomodulatory Effects of Lenalidomide and Bortezomib on Bone Marrow Stroma Cell and CD4 T Cell Interaction in Multiple Myeloma.
Blood, 2008, 112, 1690-1690
4.20Citations (PDF)
530The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Potent and Selective Cytotoxicity against CD138 Positive Multiple Myeloma Cells in Vitro and in Vivo.
Blood, 2008, 112, 1716-1716
4.23Citations (PDF)
531Compartment-Specific Bioluminescence Imaging (CS-BLI) High- Throughput Assays Provide Comparative Insights into the Impact of Osteoclasts Vs. Stromal Cells on Activity of Anti-Myeloma Therapeutics
Blood, 2008, 112, 219-219
4.231Citations (PDF)
532TH17 Pathway Promotes Tumor Cell Growth and Suppresses Immune Function in Myeloma: Potential for Therapeutic Application
Blood, 2008, 112, 2737-2737
4.20Citations (PDF)
533Emerging drugs in multiple myeloma2.411Citations (PDF)
534Hepatic Veno-Occlusive Disease after Hematopoietic Stem Cell Transplantation: Review and Update on the Use of Defibrotide2.641Citations (PDF)
535New Drugs for Myeloma
Oncologist, 2007, 12, 664-689
3.5146Citations (PDF)
536Novel Therapy with 2-Methoxyestradiol for the Treatment of Relapsed and Plateau Phase Multiple Myeloma
Clinical Cancer Research, 2007, 13, 6162-6167
6.971Citations (PDF)
537The Treatment of Relapsed and Refractory Multiple Myeloma2.953Citations (PDF)
538Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis
Blood, 2007, 110, 1656-1663
4.2109Citations (PDF)
539Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
Blood, 2007, 109, 3177-3188
4.2404Citations (PDF)
540Novel therapies in myeloma2.818Citations (PDF)
541High-dose Therapy with Single Autologous Transplantation versus Chemotherapy for Newly Diagnosed Multiple Myeloma: A Systematic Review and Meta-analysis of Randomized Controlled Trials1.6226Citations (PDF)
542Targeting the vascular endothelial growth factor pathway in the treatment of multiple myeloma2.612Citations (PDF)
543Management of Relapsed and Relapsed Refractory Myeloma2.38Citations (PDF)
544The Role of the Bone Marrow Microenvironment in the Pathophysiology of Myeloma and Its Significance in the Development of More Effective Therapies2.3111Citations (PDF)
545From the bench to the bedside: emerging new treatments in multiple myeloma1.865Citations (PDF)
546Toward a new therapeutic backbone in myeloma
Blood, 2007, 109, 2672-2673
4.26Citations (PDF)
547Predictive value of alkaline phosphatase for response and time to progression in bortezomib-treated multiple myeloma patients6.136Citations (PDF)
548Multiple myeloma: A prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment3.183Citations (PDF)
549Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
Nature Reviews Cancer, 2007, 7, 585-598
61.8866Citations (PDF)
550Safety and efficacy of bortezomib in high-risk and elderly patients with relapsed multiple myeloma
British Journal of Haematology, 2007, 137, 429-435
2.4119Citations (PDF)
551Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells
British Journal of Haematology, 2007, 138, 783-791
2.4102Citations (PDF)
552From the bench to the bedside: emerging new treatments in multiple myeloma
Targeted Oncology, 2007, 3, 19-29
3.30Citations (PDF)
553Multi-Center Phase II Study of Perifosine (KRX-0401) Alone and in Combination with Dexamethasone (dex) for Patients with Relapsed or Relapsed/Refractory Multiple Myeloma (MM): Promising Activity as Combination Therapy with Manageable Toxicity.
Blood, 2007, 110, 1164-1164
4.218Citations (PDF)
554Tanespimycin (T) + Bortezomib (BZ) in Multiple Myeloma (MM): Confirmation of the Recommended Dose Using a Novel Formulation.
Blood, 2007, 110, 1165-1165
4.218Citations (PDF)
555Phase I/II Report from a Multicenter Trial of Perifosine (KRX-0401) + Bortezomib in Patients with Relapsed or Relapsed/Refractory Multiple Myeloma Previously Treated with Bortezomib.
Blood, 2007, 110, 1170-1170
4.210Citations (PDF)
556Final Results of a Phase I Trial of Oral Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in Patients with Advanced Multiple Myeloma.
Blood, 2007, 110, 1179-1179
4.210Citations (PDF)
557Anti-Myeloma Activity of Selective PI-3K/PDK/mTOR Inhibitor BEZ235.
Blood, 2007, 110, 1185-1185
4.22Citations (PDF)
558Phase I Study of Vaccination with Dendritic Cell Myeloma Fusions.
Blood, 2007, 110, 284-284
4.22Citations (PDF)
559Phase II Trial of Perifosine (KRX-0401) in Relapsed and/or Refractory Waldenström Macroglobulinemia: Preliminary Results.
Blood, 2007, 110, 4493-4493
4.21Citations (PDF)
560Phase II Trial of the Oral mTOR Inhibitor RAD001 (Everolimus) in Relapsed and/or Refractory Waldenstrom Macroglobulinemia: Preliminary Results.
Blood, 2007, 110, 4496-4496
4.22Citations (PDF)
561Activity of CDK1/2 Inhibitor LCQ195 Against Multiple Myeloma Cells.
Blood, 2007, 110, 1519-1519
4.210Citations (PDF)
562Combination of Proteasome Inhibitors Bortezomib and NPI-0052 Trigger In Vivo Synergistic Cytotoxicity in Multiple Myeloma.
Blood, 2007, 110, 2524-2524
4.21Citations (PDF)
563Plasmacytoid Dendritic Cells Induce Growth and Survival of Multiple Myeloma Cells: Therapeutic Application.
Blood, 2007, 110, 3507-3507
4.212Citations (PDF)
564Phase II Trial of Combination of Bortezomib and Rituximab in Relapsed and/or Refractory Waldenstrom Macroglobulinemia: Preliminary Results.
Blood, 2007, 110, 4494-4494
4.21Citations (PDF)
565In Vitro and In Vivo Anti-Myeloma Activity of PRLX, an Orally-Bioavailable Agent Against Cells with Constitutive Activation of Ras or Its Downstream Pathway.
Blood, 2007, 110, 540-540
4.21Citations (PDF)
566Low Levels of Circulating CS1, a Newly Identified Multiple Myeloma (MM) Antigen for a Novel Humanized HuLuc63 Monoclonal Antibody, Is Detected in MM Patient Sera and Correlates with Active Disease.
Blood, 2007, 110, 1509-1509
4.21Citations (PDF)
567Antimyeloma activity of heat shock protein-90 inhibition
Blood, 2006, 107, 1092-1100
4.2284Citations (PDF)
568Novel therapeutic strategies targeting growth factor signalling cascades in multiple myeloma2.489Citations (PDF)
569The emerging role of novel therapeutic agents in the management of patients with multiple myeloma
Community Oncology, 2006, 3, 575-582
0.10Citations (PDF)
570Bortezomib-Induced Tumor Lysis Syndrome in Multiple Myeloma1.949Citations (PDF)
571Bortezomib: Proteasome Inhibition as an Effective Anticancer Therapy
Annual Review of Medicine, 2006, 57, 33-47
19.5337Citations (PDF)
572Defibrotide, a Polydisperse Mixture of Single-stranded Phosphodiester Oligonucleotides with Lifesaving Activity in Severe Hepatic Veno-occlusive Disease: Clinical Outcomes and Potential Mechanisms of Action
Oligonucleotides, 2006, 16, 105-114
3.150Citations (PDF)
573The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: Interplay of growth factors, their receptors and stromal interactions
European Journal of Cancer, 2006, 42, 1564-1573
5.1193Citations (PDF)
574Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells
Blood, 2006, 107, 4053-4062
4.2404Citations (PDF)
575A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
Blood, 2006, 108, 3458-3464
4.2507Citations (PDF)
576Beyond single-agent bortezomib: combination regimens in relapsed multiple myeloma
Current Opinion in Oncology, 2006, 18, 598-608
2.233Citations (PDF)
577Proteasome Inhibition as a New Therapeutic Principle in Hematological Malignancies
Current Drug Targets, 2006, 7, 1341-1347
1.941Citations (PDF)
578FQPD, a novel immunomodulatory drug, has significant in vitro activity in multiple myeloma
British Journal of Haematology, 2006, 132, 698-704
2.44Citations (PDF)
579Extended follow-up of a phase II trial in relapsed, refractory multiple myeloma:
Cancer, 2006, 106, 1316-1319
4.1137Citations (PDF)
580Frequency, Characteristics, and Reversibility of Peripheral Neuropathy During Treatment of Advanced Multiple Myeloma With Bortezomib
Journal of Clinical Oncology, 2006, 24, 3113-3120
21.6612Citations (PDF)
581Recent Advances in the Treatment of Multiple Myeloma2.315Citations (PDF)
582Lenalidomide in multiple myeloma2.655Citations (PDF)
583Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis
Blood, 2005, 106, 1794-1800
4.2175Citations (PDF)
584Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo
Blood, 2005, 105, 4470-4476
4.259Citations (PDF)
585Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application
British Journal of Haematology, 2005, 128, 192-203
2.4318Citations (PDF)
586Response to bortezomib is associated to osteoblastic activation in patients with multiple myeloma2.4183Citations (PDF)
587Molecular characterization of PS-341 (bortezomib) resistance: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-β inhibitors
Oncogene, 2005, 24, 3121-3129
6.745Citations (PDF)
588A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib
Cancer Cell, 2005, 8, 407-419
38.5699Citations (PDF)
589Bortezomib in recurrent and/or refractory multiple myeloma
Cancer, 2005, 103, 1195-1200
4.1221Citations (PDF)
590Safety of prolonged therapy with bortezomib in relapsed or refractory multiple myeloma
Cancer, 2005, 104, 2141-2148
4.199Citations (PDF)
591Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma
Journal of Clinical Oncology, 2005, 23, 6345-6350
21.670Citations (PDF)
592Proteasome inhibitor therapy in multiple myeloma1.8153Citations (PDF)
593Bortezomib: proteasome inhibition as an effective anticancer therapy
Future Oncology, 2005, 1, 161-167
2.434Citations (PDF)
594Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma7.6586Citations (PDF)
595Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma
Blood, 2005, 106, 3777-3784
4.2318Citations (PDF)
596Proteasome inhibition as a therapeutic strategy for hematologic malignancies2.614Citations (PDF)
597Plasma Cell Problems
Journal of Clinical Oncology, 2005, 23, 3138-3140
21.612Citations (PDF)
598Proteasome Inhibition in the Treatment of Cancer
Cell Cycle, 2005, 4, 289-295
3.394Citations (PDF)
599Management of the Relapsed/Refractory Myeloma Patient: Strategies Incorporating Lenalidomide
Seminars in Hematology, 2005, 42, S9-S15
3.264Citations (PDF)
600Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma
New England Journal of Medicine, 2005, 352, 2487-2498
43.72,432Citations (PDF)
601Emerging Trends in the Clinical Use of Bortezomib in Multiple Myeloma1.97Citations (PDF)
602Proteasome Inhibition As a Novel Therapeutic Target in Human Cancer
Journal of Clinical Oncology, 2005, 23, 630-639
21.6537Citations (PDF)
603Novel biological therapies for the treatment of multiple myeloma1.846Citations (PDF)
604Proteasome inhibitors as therapeutics
Essays in Biochemistry, 2005, 41, 205-218
5.29Citations (PDF)
605Multiple Myeloma2.978Citations (PDF)
606Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma
British Journal of Haematology, 2004, 125, 343-352
2.474Citations (PDF)
607p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells
Oncogene, 2004, 23, 8766-8776
6.7134Citations (PDF)
608An update of novel therapeutic approaches for multiple myeloma4.211Citations (PDF)
609Proteasome inhibition in hematologic malignancies
Annals of Medicine, 2004, 36, 304-314
4.160Citations (PDF)
610Case 38-2004
New England Journal of Medicine, 2004, 351, 2637-2645
43.710Citations (PDF)
611Thalidomide for Patients With Relapsed Multiple Myeloma After High-Dose Chemotherapy and Stem Cell Transplantation: Results of an Open-Label Multicenter Phase 2 Study of Efficacy, Toxicity, and Biological Activity
Mayo Clinic Proceedings, 2004, 79, 875-882
3.1122Citations (PDF)
612A multiagent strategy to decrease regimen-related toxicity in children undergoing allogeneic hematopoietic stem cell transplantation1.645Citations (PDF)
613A review of the proteasome inhibitor bortezomib in multiple myeloma2.243Citations (PDF)
614Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
Blood, 2004, 103, 1787-1790
4.2281Citations (PDF)
615The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti–multiple myeloma (MM) activity and overcome bortezomib resistance
Blood, 2004, 103, 3158-3166
4.2125Citations (PDF)
616GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment
Blood, 2004, 103, 3474-3479
4.290Citations (PDF)
617Targeting mitochondria to overcome conventional and bortezomib/proteasome inhibitor PS-341 resistance in multiple myeloma (MM) cells
Blood, 2004, 104, 2458-2466
4.282Citations (PDF)
618Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma
Blood, 2004, 104, 4188-4193
4.2181Citations (PDF)
619Novel biologically based therapies for Waldenstrom's macroglobulinemia
Seminars in Oncology, 2003, 30, 309-312
1.945Citations (PDF)
620Recombinant humanized anti‐CD40 monoclonal antibody triggers autologous antibody‐dependent cell‐mediated cytotoxicity against multiple myeloma cells
British Journal of Haematology, 2003, 121, 592-596
2.447Citations (PDF)
621Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma
Oncogene, 2003, 22, 8386-8393
6.7166Citations (PDF)
622A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma
New England Journal of Medicine, 2003, 348, 2609-2617
43.72,527Citations (PDF)
623Hepatic veno-occlusive disease: pathogenesis, diagnosis and treatment2.8134Citations (PDF)
624The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
Blood, 2003, 101, 2377-2380
4.2686Citations (PDF)
625Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu
Blood, 2003, 101, 703-705
4.2115Citations (PDF)
626Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
Blood, 2003, 101, 1530-1534
4.2547Citations (PDF)
627Molecular sequelae of histone deacetylase inhibition in human malignant B cells
Blood, 2003, 101, 4055-4062
4.2296Citations (PDF)
628NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma
Blood, 2003, 102, 2615-2622
4.2222Citations (PDF)
629Prior gemtuzumab ozogamicin exposure significantly increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation
Blood, 2003, 102, 1578-1582
4.2316Citations (PDF)
630Bortezomib (PS-341): A Novel, First-in-Class Proteasome Inhibitor for the Treatment of Multiple Myeloma and Other Cancers
Cancer Control, 2003, 10, 361-369
2.4287Citations (PDF)
631Molecular sequelae of proteasome inhibition in human multiple myeloma cells7.6704Citations (PDF)
632Biologic sequelae of nuclear factor–κB blockade in multiple myeloma: therapeutic applications
Blood, 2002, 99, 4079-4086
4.2373Citations (PDF)
6332-Methoxyestradiol overcomes drug resistance in multiple myeloma cells
Blood, 2002, 100, 2187-2194
4.2111Citations (PDF)
634Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
Blood, 2002, 100, 3063-3067
4.2772Citations (PDF)
635Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and multisystem organ failure: response without significant toxicity in a high-risk population and factors predictive of outcome
Blood, 2002, 100, 4337-4343
4.2335Citations (PDF)
636Thalidomide: Emerging Role in Cancer Medicine
Annual Review of Medicine, 2002, 53, 629-657
19.5130Citations (PDF)
637NF-κB as a Therapeutic Target in Multiple Myeloma
Journal of Biological Chemistry, 2002, 277, 16639-16647
2.2845Citations (PDF)
638Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
Blood, 2002, 99, 4525-4530
4.2651Citations (PDF)
639Identification of genes regulated by Dexamethasone in multiple myeloma cells using oligonucleotide arrays
Oncogene, 2002, 21, 1346-1358
6.7173Citations (PDF)
640Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications
Oncogene, 2002, 21, 5673-5683
6.7466Citations (PDF)
641Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
Blood, 2001, 98, 210-216
4.2897Citations (PDF)
642Vascular endothelial growth factor triggers signaling cascades mediating multiple myeloma cell growth and migration
Blood, 2001, 98, 428-435
4.2406Citations (PDF)
643TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications
Blood, 2001, 98, 795-804
4.2364Citations (PDF)
644The role of tumor necrosis factor α in the pathophysiology of human multiple myeloma: therapeutic applications
Oncogene, 2001, 20, 4519-4527
6.7388Citations (PDF)
645Novel therapies targeting the myeloma cell and its bone marrow microenvironment
Seminars in Oncology, 2001, 28, 607-612
1.9171Citations (PDF)
646Novel therapies targeting the myeloma cell and its bone marrow microenvironment
Seminars in Oncology, 2001, 28, 607-612
1.9130Citations (PDF)
647Double high-dose chemotherapy with stem cell rescue (HD-SCR) in patients with breast cancer - effect of sequence2.27Citations (PDF)
648Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
Blood, 2000, 96, 2943-2950
4.2857Citations (PDF)
649Dose-Intensive Therapy for Limited-Stage Small-Cell Lung Cancer: Long-Term Outcome
Journal of Clinical Oncology, 1999, 17, 1175-1175
21.651Citations (PDF)
650THE PATHOLOGY, DIAGNOSIS, AND TREATMENT OF HEPATIC VENO-OCCLUSIVE DISEASE: CURRENT STATUS AND NOVEL APPROACHES
British Journal of Haematology, 1999, 107, 485-493
2.486Citations (PDF)
651Neutropenic enterocolitis as a complication of high dose chemotherapy with stem cell rescue in patients with solid tumors
1998, 83, 409-414
37Citations (PDF)
652Prevention and Treatment of Hepatic Venocclusive Disease after High-Dose Cytoreductive Therapy
Leukemia and Lymphoma, 1998, 31, 267-277
1.523Citations (PDF)
653Antibody-drug conjugate therapies in multiple myeloma—what’s next on the horizon?1.38Citations (PDF)