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409 PR articles • 50,983 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Opposing roles for <scp>ADAMTS2</scp> and <scp>ADAMTS14</scp> in myofibroblast differentiation and function
Journal of Pathology, 2024, 262, 90-104
5.07Citations (PDF)
2ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver
Hepatology, 2023, 77, 1211-1227
10.630Citations (PDF)
3<scp>ST3GAL5</scp>‐catalyzed gangliosides inhibit <scp>TGF</scp>‐β‐induced epithelial‐mesenchymal transition via <scp>TβRI</scp> degradation
EMBO Journal, 2023, 42,
7.434Citations (PDF)
4Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells5.614Citations (PDF)
5Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence
Cancer Communications, 2023, 43, 513-518
12.015Citations (PDF)
6Intertumoral Differences Dictate the Outcome of TGF-β Blockade on the Efficacy of Viro-Immunotherapy2.98Citations (PDF)
7Differential optineurin expression controls <scp>TGFβ</scp> signaling and is a key determinant for metastasis of triple negative breast cancer
International Journal of Cancer, 2023, 152, 2594-2606
4.58Citations (PDF)
8LncRNA LITATS1 suppresses TGF‐β‐induced EMT and cancer cell plasticity by potentiating TβRI degradation
EMBO Journal, 2023, 42,
7.461Citations (PDF)
9The lncRNA LETS1 promotes TGF-β–induced EMT and cancer cell migration by transcriptionally activating a TβR1-stabilizing mechanism
Science Signaling, 2023, 16,
5.522Citations (PDF)
10TGF-β Type I Receptor Signaling in Melanoma Liver Metastases Increases Metastatic Outgrowth4.53Citations (PDF)
11Genome-wide CRISPR screens define determinants of epithelial-mesenchymal transition mediated immune evasion by pancreatic cancer cells
Science Advances, 2023, 9,
11.019Citations (PDF)
12CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic7.622Citations (PDF)
13The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma
Journal of Cellular Physiology, 2022, 237, 743-762
4.211Citations (PDF)
14Follistatin‐controlled activin‐HNF4α‐coagulation factor axis in liver progenitor cells determines outcome of acute liver failure
Hepatology, 2022, 75, 322-337
10.625Citations (PDF)
15Combinatorial Therapeutic Approaches with Nanomaterial-Based Photodynamic Cancer Therapy
Pharmaceutics, 2022, 14, 120
5.151Citations (PDF)
16RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis8.718Citations (PDF)
17Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches
Cell, 2022, 185, 379-396.e38
34.1799Citations (PDF)
18CD161 expression and regulation defines rapidly responding effector CD4+ T cells associated with improved survival in HPV16-associated tumors
2022, 10, e003995
30Citations (PDF)
19Transforming growth factor-β challenge alters the N-, O-, and glycosphingolipid glycomes in PaTu-S pancreatic adenocarcinoma cells2.28Citations (PDF)
20TGFβ selects for pro‐stemness over pro‐invasive phenotypes during cancer cell epithelial–mesenchymal transition
Molecular Oncology, 2022, 16, 2330-2354
4.213Citations (PDF)
21A Programmable Multifunctional 3D Cancer Cell Invasion Micro Platform
Small, 2022, 18,
11.69Citations (PDF)
22Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP1013.916Citations (PDF)
23Microfluidics meets 3D cancer cell migration
Trends in Cancer, 2022, 8, 683-697
10.661Citations (PDF)
24OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor43.936Citations (PDF)
25Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
Cancers, 2022, 14, 2508
4.016Citations (PDF)
26Photodynamic Therapy in Combination with the Hepatitis B Core Virus-like Particles (HBc VLPs) to Prime Anticancer Immunity for Colorectal Cancer Treatment
Cancers, 2022, 14, 2724
4.018Citations (PDF)
27Synthesis and preclinical evaluation of [11C]LR111 and [18F]EW-7197 as PET tracers of the activin-receptor like kinase-5
Nuclear Medicine and Biology, 2022, 112-113, 9-19
0.31Citations (PDF)
28Low Transforming Growth Factor-β Pathway Activity in Cervical Adenocarcinomas2.75Citations (PDF)
29TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling
Molecular Cancer Research, 2022, 20, 1516-1531
3.220Citations (PDF)
30<scp>USP8</scp> promotes cancer progression and extracellular vesicle‐mediated <scp>CD8</scp>+ T cell exhaustion by deubiquitinating the <scp>TGF</scp>‐β receptor <scp>TβRII</scp>
EMBO Journal, 2022, 41,
7.477Citations (PDF)
31E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression4.525Citations (PDF)
32A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis
Genome Biology, 2021, 22,
8.222Citations (PDF)
33Targeting TGFβ signal transduction for cancer therapy43.9346Citations (PDF)
34TGF-&amp;#946;-mediated Endothelial to Mesenchymal Transition (EndMT) and the Functional Assessment of EndMT Effectors using CRISPR/Cas9 Gene Editing0.39Citations (PDF)
35TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors3.742Citations (PDF)
36Challenges and Opportunities for Drug Repositioning in Fibrodysplasia Ossificans Progressiva
Biomedicines, 2021, 9, 213
3.513Citations (PDF)
37Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation
Cell Stem Cell, 2021, 28, 653-670.e11
16.851Citations (PDF)
38Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors
Cancers, 2021, 13, 2951
4.06Citations (PDF)
39Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling
Angiogenesis, 2021, 25, 99-112
7.916Citations (PDF)
40Cripto favors chondrocyte hypertrophy via <scp>TGF</scp>‐β <scp>SMAD1</scp>/5 signaling during development of osteoarthritis
Journal of Pathology, 2021, 255, 330-342
5.017Citations (PDF)
41Metabolic Reprogramming of Mammary Epithelial Cells during TGF-β-Induced Epithelial-to-Mesenchymal Transition
Metabolites, 2021, 11, 626
3.515Citations (PDF)
42Therapeutic targeting of TGF-β in cancer: hacking a master switch of immune suppression
Clinical Science, 2021, 135, 35-52
6.466Citations (PDF)
43The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma8.76Citations (PDF)
44Breast cancer dormancy is associated with a 4NG1 state and not senescence6.520Citations (PDF)
45Cancer associated-fibroblast-derived exosomes in cancer progression
Molecular Cancer, 2021, 20,
32.3285Citations (PDF)
46VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation3.615Citations (PDF)
47THG-1 suppresses SALL4 degradation to induce stemness genes and tumorsphere formation through antagonizing NRBP1 in squamous cell carcinoma cells2.114Citations (PDF)
48Deubiquitinase Activity Profiling Identifies UCHL1 as a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis
Clinical Cancer Research, 2020, 26, 1460-1473
6.9124Citations (PDF)
49Current perspectives on inhibitory SMAD7 in health and disease6.868Citations (PDF)
50TGF‐β signaling in liver metastasis5.748Citations (PDF)
51Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis
Cancer Letters, 2020, 493, 41-54
8.824Citations (PDF)
52Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Biomaterials, 2020, 259, 120331
12.341Citations (PDF)
53Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos15.071Citations (PDF)
54Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish2.09Citations (PDF)
55TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering3.7211Citations (PDF)
56Secreted BMP antagonists and their role in cancer and bone metastases
Bone, 2020, 137, 115455
3.628Citations (PDF)
57MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension4.55Citations (PDF)
58Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors
Bone, 2020, 138, 115472
3.6107Citations (PDF)
59Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior2.724Citations (PDF)
60A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival
Cells, 2020, 9, 752
4.813Citations (PDF)
61Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses
Trends in Immunology, 2020, 41, 406-420
10.663Citations (PDF)
62Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas
Cancer Cell, 2020, 37, 308-323.e12
38.579Citations (PDF)
63On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges?3.7183Citations (PDF)
64TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness
Oncogene, 2020, 39, 4436-4449
6.783Citations (PDF)
65Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress–Activated FOXO1 to Trigger β-Cell Failure
Diabetes, 2020, 69, 193-204
4.430Citations (PDF)
66Development of a 96-well plate sample preparation method for integrated<i>N</i>- and<i>O</i>-glycomics using porous graphitized carbon liquid chromatography-mass spectrometry
Molecular Omics, 2020, 16, 355-363
2.464Citations (PDF)
67Role of glycosylation in TGF-β signaling and epithelial-to-mesenchymal transition in cancer
Protein and Cell, 2020, 12, 89-106
3.666Citations (PDF)
68Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells7.634Citations (PDF)
69Studying TGF-&amp;#946; Signaling and TGF-&amp;#946;-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells0.315Citations (PDF)
70Uncovering the deubiquitinase activity landscape of breast cancer
Oncoscience, 2020, 7, 85-87
1.32Citations (PDF)
71Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension
Journal of Pathology, 2019, 249, 356-367
5.045Citations (PDF)
72Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling
European Respiratory Journal, 2019, 54, 1802400
12.133Citations (PDF)
73In vivo imaging of TGFβ signalling components using positron emission tomography
Drug Discovery Today, 2019, 24, 2258-2272
6.88Citations (PDF)
74GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients8.144Citations (PDF)
75Generation of Fibrodysplasia ossificans progressiva and control integration free iPSC lines from periodontal ligament fibroblasts
Stem Cell Research, 2019, 41, 101639
0.68Citations (PDF)
76Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells
JBMR Plus, 2019, 3,
2.137Citations (PDF)
77Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression4.9144Citations (PDF)
78c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression13.957Citations (PDF)
79Role of soluble endoglin in BMP9 signaling7.675Citations (PDF)
80Generation of non-standard macrocyclic peptides specifically binding TSC-22 homologous gene-12.15Citations (PDF)
81Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer
Cancers, 2019, 11, 726
4.065Citations (PDF)
82TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis4.5984Citations (PDF)
83DIPG-13. A NOVEL MOUSE MODEL REVEALS UNEXPECTED MECHANISMS OF ACTION OF ACVR1 MUTATIONS IN DIFFUSE INTRINSIC PONTINE GLIOMA
Neuro-Oncology, 2019, 21, ii71-ii71
1.10Citations (PDF)
84Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models
Cells, 2019, 8, 320
4.8104Citations (PDF)
85JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses
Cells, 2019, 8, 1481
4.818Citations (PDF)
86A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment
Biomolecules, 2019, 9, 743
4.4164Citations (PDF)
87Inflammation induces endothelial‐to‐mesenchymal transition and promotes vascular calcification through downregulation of BMPR2
Journal of Pathology, 2019, 247, 333-346
5.0177Citations (PDF)
88TGF-β Family Signaling Pathways in Cellular Dormancy
Trends in Cancer, 2019, 5, 66-78
10.677Citations (PDF)
89Bone morphogenetic protein receptor signal transduction in human disease
Journal of Pathology, 2019, 247, 9-20
5.0206Citations (PDF)
90TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer5.6220Citations (PDF)
91JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion
Nucleic Acids Research, 2018, 46, 1180-1195
15.7102Citations (PDF)
92TGF-&amp;beta; family co-receptor function and signaling2.1194Citations (PDF)
93TGF-β Signaling in Control of Cardiovascular Function7.3336Citations (PDF)
94Bone Morphogenetic Proteins in Vascular Homeostasis and Disease7.3140Citations (PDF)
95Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis
Clinical Cancer Research, 2018, 24, 6331-6344
6.9158Citations (PDF)
96Epithelial–mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?
Oncogene, 2018, 37, 6195-6211
6.7150Citations (PDF)
97Bone morphogenetic protein 9 as a key regulator of liver progenitor cells in <scp>DDC</scp>‐induced cholestatic liver injury
Liver International, 2018, 38, 1664-1675
4.132Citations (PDF)
98The therapeutic potential of targeting the endothelial-to-mesenchymal transition
Angiogenesis, 2018, 22, 3-13
7.997Citations (PDF)
99Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice
Oncogenesis, 2017, 6, e294-e294
5.722Citations (PDF)
100TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation
Journal of Biological Chemistry, 2017, 292, 4099-4112
2.230Citations (PDF)
101Targeting TGF-β Signaling in Cancer
Trends in Cancer, 2017, 3, 56-71
10.6898Citations (PDF)
102Fluid shear stress-induced TGF-β/ALK5 signaling in renal epithelial cells is modulated by MEK1/25.635Citations (PDF)
103FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis13.943Citations (PDF)
104BMP type II receptor as a therapeutic target in pulmonary arterial hypertension5.6100Citations (PDF)
105SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death
Cell Death and Differentiation, 2017, 24, 1530-1539
13.752Citations (PDF)
106BMP-9 interferes with liver regeneration and promotes liver fibrosis
Gut, 2017, 66, 939-954
21.2141Citations (PDF)
107Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish0.331Citations (PDF)
108Endoglin as an Important Regulator of Colorectal Cancer Invasion and Metastasis
Gastroenterology, 2017, 152, S87
1.00Citations (PDF)
109Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model
Renal Failure, 2017, 39, 629-642
2.710Citations (PDF)
110Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD713.9113Citations (PDF)
111TGFβ1-induced SMAD2/3 and SMAD1/5 phosphorylation are both ALK5-kinase-dependent in primary chondrocytes and mediated by TAK1 kinase activity4.261Citations (PDF)
112New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration
FASEB Journal, 2017, 31, 238-255
0.730Citations (PDF)
113Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation2.938Citations (PDF)
114TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases4.5326Citations (PDF)
115ALK1Fc Suppresses the Human Prostate Cancer Growth in in Vitro and in Vivo Preclinical Models3.74Citations (PDF)
116Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model3.545Citations (PDF)
117Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease0.445Citations (PDF)
118c-Myb Enhances Breast Cancer Invasion and Metastasis through the Wnt/β-Catenin/Axin2 Pathway
Cancer Research, 2016, 76, 3364-3375
0.6121Citations (PDF)
119Regulation of the TGF-β pathway by deubiquitinases in cancer2.730Citations (PDF)
120Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression
American Journal of Pathology, 2016, 186, 1874-1889
3.430Citations (PDF)
121Immunoregulation by members of the TGFβ superfamily
Nature Reviews Immunology, 2016, 16, 723-740
56.7329Citations (PDF)
122Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function4.143Citations (PDF)
123A current perspective on applications of macrocyclic‐peptide‐based high‐affinity ligands
Biopolymers, 2016, 106, 889-900
2.924Citations (PDF)
124Expression of TGFβ-family signalling components in ageing cartilage: age-related loss of TGFβ and BMP receptors
Osteoarthritis and Cartilage, 2016, 24, 1235-1245
5.742Citations (PDF)
125<scp>TGF</scp>‐β signalling and liver disease
FEBS Journal, 2016, 283, 2219-2232
5.5568Citations (PDF)
126The rationale for targeting <scp>TGF</scp>‐β in chronic liver diseases3.373Citations (PDF)
127Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors
Clinical Cancer Research, 2016, 22, 96-106
6.950Citations (PDF)
128Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells
Oncotarget, 2016, 7, 81995-82012
1.721Citations (PDF)
129Towards a cure for Fibrodysplasia ossificans progressiva1.810Citations (PDF)
130Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels3.528Citations (PDF)
131A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins
Journal of Virology, 2015, 89, 8318-8333
3.773Citations (PDF)
132Signal Transduction: Gain of Activin Turns Muscle into Bone
Current Biology, 2015, 25, R1136-R1138
3.63Citations (PDF)
133The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1
Osteoarthritis and Cartilage, 2015, 23, 985-995
5.731Citations (PDF)
134Bone morphogenetic protein signaling in bone homeostasis
Bone, 2015, 80, 43-59
3.6203Citations (PDF)
135SLUG Is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification6.347Citations (PDF)
136Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2
Gastroenterology, 2015, 148, 1427-1437.e8
1.059Citations (PDF)
137Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models4.953Citations (PDF)
138Clinical Utility Gene Card for: Fibrodysplasia ossificans progressiva3.224Citations (PDF)
139Heterozygous disruption of activin receptor-like kinase 1 is associated with increased arterial pressure2.08Citations (PDF)
140Bone morphogenetic protein 6 and oxidized low-density lipoprotein synergistically recruit osteogenic differentiation in endothelial cells
Cardiovascular Research, 2015, 108, 278-287
5.789Citations (PDF)
141Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice
Archives of Toxicology, 2015, 90, 347-357
6.135Citations (PDF)
142Targeting BMP signalling in cardiovascular disease and anaemia
Nature Reviews Cardiology, 2015, 13, 106-120
37.5228Citations (PDF)
143Ter94/VCP Is a Novel Component Involved in BMP Signaling
PLoS ONE, 2014, 9, e114475
2.411Citations (PDF)
144Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling13.9179Citations (PDF)
145Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides5.625Citations (PDF)
146Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene2.424Citations (PDF)
147Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor5.633Citations (PDF)
148Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β5.542Citations (PDF)
149Functionality of Endothelial Cells and Pericytes From Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts6.3192Citations (PDF)
150Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK
Gastroenterology, 2014, 147, 196-208.e13
1.0163Citations (PDF)
151P348Impaired macrophage polarization in endoglin haplo-insufficiency leading to defective tissue repair is recovered by counter balance the TGFbeta pathway
Cardiovascular Research, 2014, 103, S63.4-S63
5.70Citations (PDF)
152The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC
British Journal of Cancer, 2014, 112, 122-130
5.774Citations (PDF)
153ENDOGLIN Is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-Induced Angiogenesis
PLoS ONE, 2014, 9, e86273
2.465Citations (PDF)
154TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis
Molecular Cell, 2013, 51, 559-572
13.4220Citations (PDF)
155Animal models of chronic liver diseases3.4200Citations (PDF)
156Signaling interplay between transforming growth factor-β receptor and PI3K/AKT pathways in cancer6.7243Citations (PDF)
157Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis
Nature Medicine, 2013, 19, 421-428
39.586Citations (PDF)
158Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device
Lab on A Chip, 2013, 13, 3562
5.2147Citations (PDF)
159Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion2.1128Citations (PDF)
160UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination
Cell Research, 2013, 23, 366-377
12.583Citations (PDF)
161Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination9.4120Citations (PDF)
162Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation
Journal of Biological Chemistry, 2013, 288, 30708-30719
2.2175Citations (PDF)
163The prognostic role of TGF-β signaling pathway in breast cancer patients
Annals of Oncology, 2013, 24, 384-390
10.287Citations (PDF)
164Endoglin for tumor imaging and targeted cancer therapy3.940Citations (PDF)
165Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6
EMBO Journal, 2013, 32, 996-1007
7.484Citations (PDF)
166Activin receptor-like kinase 1 as a target for anti-angiogenesis therapy4.036Citations (PDF)
167Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model4.9112Citations (PDF)
168Antisense-Oligonucleotide Mediated Exon Skipping in Activin-Receptor-Like Kinase 2: Inhibiting the Receptor That Is Overactive in Fibrodysplasia Ossificans Progressiva
PLoS ONE, 2013, 8, e69096
2.436Citations (PDF)
169FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension
Journal of Clinical Investigation, 2013, 123, 3600-3613
10.7405Citations (PDF)
170Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling
PLoS ONE, 2013, 8, e62295
2.457Citations (PDF)
171Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition
PLoS ONE, 2013, 8, e81710
2.430Citations (PDF)
172Ubiquitin-specific Protease 4 Mitigates Toll-like/Interleukin-1 Receptor Signaling and Regulates Innate Immune Activation
Journal of Biological Chemistry, 2012, 287, 11002-11010
2.280Citations (PDF)
173Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer
Cancer Research, 2012, 72, 1705-1716
0.659Citations (PDF)
174Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting
Journal of Biological Chemistry, 2012, 287, 18551-18561
2.293Citations (PDF)
175Fas-associated Factor 1 Is a Scaffold Protein That Promotes β-Transducin Repeat-containing Protein (β-TrCP)-mediated β-Catenin Ubiquitination and Degradation
Journal of Biological Chemistry, 2012, 287, 30701-30710
2.234Citations (PDF)
176Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva
Current Pharmaceutical Design, 2012, 18, 4087-4092
2.45Citations (PDF)
177TGFβ Signaling in Liver Regeneration
Current Pharmaceutical Design, 2012, 18, 4103-4113
2.464Citations (PDF)
178Tgf-β Signaling In Duchenne Muscular Dystrophy
Future Neurology, 2012, 7, 209-224
0.55Citations (PDF)
179A Covalently Dimerized Recombinant Human Bone Morphogenetic Protein-15 Variant Identifies Bone Morphogenetic Protein Receptor Type 1B as a Key Cell Surface Receptor on Ovarian Granulosa Cells
Endocrinology, 2012, 153, 1509-1518
2.643Citations (PDF)
180Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity4.936Citations (PDF)
181MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling
Cell, 2012, 151, 937-950
34.1414Citations (PDF)
182USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor
Nature Cell Biology, 2012, 14, 717-726
16.9292Citations (PDF)
183Cell‐type specific regulation of myostatin signaling
FASEB Journal, 2012, 26, 1462-1472
0.763Citations (PDF)
184Key role for ubiquitin protein modification in TGFβ signal transduction0.847Citations (PDF)
185RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation
Molecular Cell, 2012, 46, 650-661
13.493Citations (PDF)
186Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression2.118Citations (PDF)
187LRP8 mediates Wnt/β-catenin signaling and controls osteoblast differentiation5.057Citations (PDF)
188Shear induced collateral artery growth modulated by endoglin but not by <scp>ALK1</scp>4.138Citations (PDF)
189The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma
European Journal of Cancer, 2012, 48, 3429-3438
5.143Citations (PDF)
190Soluble fms-like tyrosine kinase 1 and soluble endoglin are elevated circulating anti-angiogenic factors in pre-eclampsia
Pregnancy Hypertension, 2012, 2, 358-367
1.623Citations (PDF)
191TGFβ Signaling and Cardiovascular Diseases8.889Citations (PDF)
192MicroRNA-155 Functions as a Negative Regulator of RhoA Signaling in TGF-β-induced Endothelial to Mesenchymal Transition1.248Citations (PDF)
193TGF-β signalling and its role in cancer progression and metastasis7.2412Citations (PDF)
194BMP signaling in vascular diseases
FEBS Letters, 2012, 586, 1993-2002
2.7254Citations (PDF)
195Nonsynonymous variants in the<i>SMAD6</i>gene predispose to congenital cardiovascular malformation
Human Mutation, 2012, 33, 720-727
3.9128Citations (PDF)
196Regulation of endothelial barrier function by TGF‐β type I receptor ALK5: Potential role of contractile mechanisms and heat shock protein 90
Journal of Cellular Physiology, 2012, 227, 759-771
4.221Citations (PDF)
197Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy5.639Citations (PDF)
198Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion
Oncogene, 2012, 32, 3606-3615
6.799Citations (PDF)
199Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts
Oncogene, 2012, 33, 97-107
6.7244Citations (PDF)
200TGFβ Signaling and Cardiovascular Diseases8.8161Citations (PDF)
201Exploring anti-TGF-β therapies in cancer and fibrosis
Growth Factors, 2011, 29, 140-152
1.8144Citations (PDF)
202Temporal Smad7 Transgene Induction in Mouse Epidermis Accelerates Skin Wound Healing
American Journal of Pathology, 2011, 179, 1768-1779
3.437Citations (PDF)
203Spheroid Assay to Measure TGF-β-induced Invasion0.328Citations (PDF)
204ALK2 mutation in a patient with Down's syndrome and a congenital heart defect3.240Citations (PDF)
205BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model
Neurobiology of Disease, 2011, 41, 353-360
5.235Citations (PDF)
206Activin A induces a non-fibrotic phenotype in smooth muscle cells in contrast to TGF-β
Experimental Cell Research, 2011, 317, 131-142
3.212Citations (PDF)
207TGF-β Signaling in Breast Cancer Cell Invasion and Bone Metastasis3.2152Citations (PDF)
208Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts2.960Citations (PDF)
209Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy1.842Citations (PDF)
210The dynamic roles of TGF‐β in cancer
Journal of Pathology, 2011, 223, 206-219
5.0353Citations (PDF)
211Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts
Journal of Cellular Physiology, 2011, 226, 3340-3348
4.272Citations (PDF)
212Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells
Developmental Dynamics, 2011, 240, 1670-1680
1.863Citations (PDF)
213Biphasic effects of transforming growth factor β on bone morphogenetic protein–induced osteoblast differentiation5.084Citations (PDF)
214Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation
Molecular Biology of the Cell, 2011, 22, 1617-1624
2.552Citations (PDF)
215TGFβ Activates Mitogen- and Stress-activated Protein Kinase-1 (MSK1) to Attenuate Cell Death
Journal of Biological Chemistry, 2011, 286, 5003-5011
2.228Citations (PDF)
216GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb
Molecular Biology of the Cell, 2011, 22, 3533-3540
2.554Citations (PDF)
217TGF-β1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus
Cardiovascular Research, 2011, 91, 510-518
5.739Citations (PDF)
218Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition
Circulation Research, 2011, 108, 1093-1101
12.5188Citations (PDF)
219BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β3 expression4.257Citations (PDF)
220Age-dependent alteration of TGF-β signalling in osteoarthritis
Cell and Tissue Research, 2011, 347, 257-265
2.7135Citations (PDF)
221Regulation of endothelial cell plasticity by TGF-β
Cell and Tissue Research, 2011, 347, 177-186
2.7323Citations (PDF)
222TGF-β in progression of liver disease
Cell and Tissue Research, 2011, 347, 245-256
2.7692Citations (PDF)
223TGF-&amp;#946; Receptor Signaling Pathways in Angiogenesis; Emerging Targets for Anti-Angiogenesis Therapy2.366Citations (PDF)
224ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation5.0155Citations (PDF)
225Signaling by members of the TGF-β family in vascular morphogenesis and disease
Trends in Cell Biology, 2010, 20, 556-567
12.3378Citations (PDF)
226Elevated TGFβ–Smad signalling in experimental <i>Pkd1</i> models and human patients with polycystic kidney disease
Journal of Pathology, 2010, 222, 21-31
5.093Citations (PDF)
227Annexin A1 regulates TGF-β signaling and promotes metastasis formation of basal-like breast cancer cells7.6203Citations (PDF)
228Identification of a Key Residue Mediating Bone Morphogenetic Protein (BMP)-6 Resistance to Noggin Inhibition Allows for Engineered BMPs with Superior Agonist Activity
Journal of Biological Chemistry, 2010, 285, 12169-12180
2.2113Citations (PDF)
229Matrix Metalloproteinase-14 (MT1-MMP)–Mediated Endoglin Shedding Inhibits Tumor Angiogenesis
Cancer Research, 2010, 70, 4141-4150
0.6247Citations (PDF)
230In Situ Proximity Ligation Detection of c-Jun/AP-1 Dimers Reveals Increased Levels of c-Jun/Fra1 Complexes in Aggressive Breast Cancer Cell Lines in Vitro and in Vivo3.025Citations (PDF)
231Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis9.4164Citations (PDF)
232Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways
Journal of Biological Chemistry, 2010, 285, 41614-41626
2.2164Citations (PDF)
233TMEPAI, a Transmembrane TGF-β-Inducible Protein, Sequesters Smad Proteins from Active Participation in TGF-β Signaling
Molecular Cell, 2010, 37, 123-134
13.4152Citations (PDF)
2345-Aminosalicylic acid inhibits TGF-β1 signalling in colorectal cancer cells
Cancer Letters, 2010, 287, 82-90
8.822Citations (PDF)
235Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma
Oncogene, 2010, 30, 334-345
6.779Citations (PDF)
236The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system2.4197Citations (PDF)
237VEGF and inhibitors of TGFβ type-I receptor kinase synergistically promote blood-vessel formation by inducing α5-integrin expression
Journal of Cell Science, 2009, 122, 3294-3302
2.592Citations (PDF)
238Smad3 Is a Key Nonredundant Mediator of Transforming Growth Factor β Signaling in Nme Mouse Mammary Epithelial Cells
Molecular Cancer Research, 2009, 7, 1342-1353
3.228Citations (PDF)
239Dominant-Negative <i>ALK2</i> Allele Associates With Congenital Heart Defects
Circulation, 2009, 119, 3062-3069
25.2100Citations (PDF)
240Ski co‐repressor complexes maintain the basal repressed state of the TGF‐β target gene, <i>SMAD7</i>, via HDAC3 and PRMT5
Genes To Cells, 2009, 14, 17-28
1.561Citations (PDF)
241Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation
Laboratory Investigation, 2009, 89, 800-810
3.320Citations (PDF)
242Ionizing Radiation Shifts the PAI-1/ID-1 Balance and Activates Notch Signaling in Endothelial Cells1.684Citations (PDF)
243Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidneys
Radiotherapy and Oncology, 2009, 92, 484-491
2.041Citations (PDF)
244Transforming growth factor-beta signaling and tumor angiogenesis6.0109Citations (PDF)
245Autocrine Bone Morphogenetic Protein-9 Signals through Activin Receptor-like Kinase-2/Smad1/Smad4 to Promote Ovarian Cancer Cell Proliferation
Cancer Research, 2009, 69, 9254-9262
0.6115Citations (PDF)
246Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
Oncogene, 2009, 29, 1351-1361
6.7176Citations (PDF)
247Shear stress modulates TGF‐beta signaling and EMT in endothelial cells
FASEB Journal, 2009, 23,
0.70Citations (PDF)
248Endoglin in angiogenesis and vascular diseases
Angiogenesis, 2008, 11, 79-89
7.9310Citations (PDF)
249Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate
Arthritis and Rheumatism, 2008, 58, 2528-2537
6.077Citations (PDF)
250ALK1 Opposes ALK5/Smad3 Signaling and Expression of Extracellular Matrix Components in Human Chondrocytes5.0147Citations (PDF)
251VE-cadherin is a critical endothelial regulator of TGF-β signalling
EMBO Journal, 2008, 27, 993-1004
7.4155Citations (PDF)
252Transforming Growth Factor β and Wound Healing in Human Cholesteatoma
Laryngoscope, 2008, 118, 94-98
1.528Citations (PDF)
253Transforming Growth Factor β–Induced Endothelial-to-Mesenchymal Transition: A Switch to Cardiac Fibrosis?7.5159Citations (PDF)
254The Bone Morphogenetic Protein Pathway Is Inactivated in the Majority of Sporadic Colorectal Cancers
Gastroenterology, 2008, 134, 1332-1341.e3
1.0155Citations (PDF)
255Two novel type II receptors mediate BMP signalling and are required to establish left–right asymmetry in zebrafish
Developmental Biology, 2008, 315, 55-71
1.955Citations (PDF)
256Osteocyte-Derived Sclerostin Inhibits Bone Formation: Its Role in Bone Morphogenetic Protein and Wnt Signaling3.4199Citations (PDF)
257L- and S-endoglin differentially modulate TGFβ1 signaling mediated by ALK1 and ALK5 in L6E9 myoblasts
Journal of Cell Science, 2008, 121, 913-919
2.5112Citations (PDF)
258Oral administration of GW788388, an inhibitor of TGF-β type I and II receptor kinases, decreases renal fibrosis
Kidney International, 2008, 73, 705-715
5.0203Citations (PDF)
259Role of TGF- &amp;#946; in the Tumor Stroma
Current Cancer Drug Targets, 2008, 8, 466-472
2.521Citations (PDF)
260TGF-β signaling in vascular biology and dysfunction
Cell Research, 2008, 19, 116-127
12.5570Citations (PDF)
261Wnt but Not BMP Signaling Is Involved in the Inhibitory Action of Sclerostin on BMP-Stimulated Bone Formation5.0252Citations (PDF)
262Transforming Growth Factor-β Receptor Type I-dependent Fibrogenic Gene Program Is Mediated via Activation of Smad1 and ERK1/2 Pathways
Journal of Biological Chemistry, 2007, 282, 10405-10413
2.2177Citations (PDF)
263KLF2 Suppresses TGF-β Signaling in Endothelium Through Induction of Smad7 and Inhibition of AP-16.3113Citations (PDF)
264Compensatory signalling induced in the yolk sac vasculature by deletion of TGFβ receptors in mice
Journal of Cell Science, 2007, 120, 4269-4277
2.5111Citations (PDF)
265Signaling by ALK5 mediates TGF-β-induced ET-1 expression in endothelial cells: a role for migration and proliferation
Journal of Cell Science, 2007, 120, 1256-1266
2.594Citations (PDF)
266BMP7, a Putative Regulator of Epithelial Homeostasis in the Human Prostate, Is a Potent Inhibitor of Prostate Cancer Bone Metastasis in Vivo
American Journal of Pathology, 2007, 171, 1047-1057
3.4194Citations (PDF)
267TMEPAI, a transmembrane TGF-β-inducible protein, sequesters Smad proteins in TGF-β signaling0.10Citations (PDF)
268SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development
Developmental Dynamics, 2007, 236, 606-612
1.843Citations (PDF)
269Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia
Developmental Dynamics, 2007, 236, 746-754
1.875Citations (PDF)
270A rapid and sensitive bioassay to measure bone morphogenetic protein activity
BMC Cell Biology, 2007, 8,
3.969Citations (PDF)
271Extracellular control of TGFβ signalling in vascular development and disease78.9754Citations (PDF)
272Negative regulation of TGF-β receptor/Smad signal transduction3.9369Citations (PDF)
273TGF-β and BMP7 interactions in tumour progression and bone metastasis2.8112Citations (PDF)
274The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Cancer Research, 2006, 66, 2202-2209
0.6360Citations (PDF)
275Methylation of Smad6 by protein arginineN-methyltransferase 1
FEBS Letters, 2006, 580, 6603-6611
2.728Citations (PDF)
276A Rate Equation Approach to Elucidate the Kinetics and Robustness of the TGF-β Pathway
Biophysical Journal, 2006, 91, 4368-4380
2.251Citations (PDF)
277Bone morphogenetic protein signal transduction in bone2.270Citations (PDF)
278Smad7-Induced β-Catenin Degradation Alters Epidermal Appendage Development
Developmental Cell, 2006, 11, 301-312
7.8155Citations (PDF)
279Title is missing!
BMC Cell Biology, 2006, 7, 16
3.950Citations (PDF)
280An assay for the determination of biologically active bone morphogenetic proteins using cells transfected with an inhibitor of differentiation promoter-luciferase construct
Analytical Biochemistry, 2006, 349, 78-86
2.454Citations (PDF)
281Id1 is a critical mediator in TGF-β-induced transdifferentiation of rat hepatic stellate cells
Hepatology, 2006, 43, 1032-1041
10.6137Citations (PDF)
282Endoglin Has a Crucial Role in Blood Cell–Mediated Vascular Repair
Circulation, 2006, 114, 2288-2297
25.2128Citations (PDF)
283New mechanisms of skin innate immunity: ASK1-mediated keratinocyte differentiation regulates the expression of β-defensins, LL37, and TLR2
European Journal of Immunology, 2005, 35, 1886-1895
3.269Citations (PDF)
284Global Analysis of Smad2/3-Dependent TGF-β Signaling in Living Mice Reveals Prominent Tissue-Specific Responses to Injury
Journal of Immunology, 2005, 175, 547-554
0.6106Citations (PDF)
285TGF-? receptor function in the endothelium
Cardiovascular Research, 2005, 65, 599-608
5.7480Citations (PDF)
286SOST/sclerostin, an osteocyte-derived negative regulator of bone formation10.8335Citations (PDF)
287Transforming Growth Factor-β1 to the Bone
Endocrine Reviews, 2005, 26, 743-774
25.8668Citations (PDF)
288Control of bone formation by osteocytes? lessons from the rare skeletal disorders sclerosteosis and van Buchem disease
BoneKEy Osteovision, 2005, 2, 33-38
0.46Citations (PDF)
289Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins
Journal of Cell Science, 2004, 117, 4653-4663
2.589Citations (PDF)
290Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist9.4832Citations (PDF)
291Defective paracrine signalling by TGFβ in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia
Development (Cambridge), 2004, 131, 6237-6247
3.1142Citations (PDF)
292Nerve growth factor mediates activation of the Smad pathway in PC12 cells
FEBS Journal, 2004, 271, 920-931
0.235Citations (PDF)
293Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells
EMBO Journal, 2004, 23, 541-551
7.4227Citations (PDF)
294Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction
EMBO Journal, 2004, 23, 4018-4028
7.4630Citations (PDF)
295New insights into TGF-β–Smad signalling6.71,126Citations (PDF)
296Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction
Developmental Dynamics, 2004, 231, 542-550
1.8100Citations (PDF)
297RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-β (TGF-β) target gene that negatively regulates transcriptional activity induced by TGF-β
Biochemical Journal, 2004, 383, 187-199
3.917Citations (PDF)
298Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor-Induced Osteoblast Differentiation5.055Citations (PDF)
299Controlling mesenchymal stem cell differentiation by TGFβ family members1.3163Citations (PDF)
300Distribution of phosphorylated Smad2 identifies target tissues of TGFβ ligands in mouse development
Gene Expression Patterns, 2003, 3, 355-360
0.937Citations (PDF)
301Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats
Gastroenterology, 2003, 125, 178-191
1.0360Citations (PDF)
302Controlling cell fate by bone morphogenetic protein receptors3.5183Citations (PDF)
303Bone morphogenetic protein signalling in NGF-stimulated PC12 cells2.110Citations (PDF)
304Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling
Molecular Cell, 2003, 12, 817-828
13.4660Citations (PDF)
305Nuclear Factor YY1 Inhibits Transforming Growth Factor β- and Bone Morphogenetic Protein-Induced Cell Differentiation
Molecular and Cellular Biology, 2003, 23, 4494-4510
2.5164Citations (PDF)
306Elucidation of Smad Requirement in Transforming Growth Factor-β Type I Receptor-induced Responses
Journal of Biological Chemistry, 2003, 278, 3751-3761
2.2192Citations (PDF)
307Transforming Growth Factor-β1 (TGF-β)–induced Apoptosis of Prostate Cancer Cells Involves Smad7-dependent Activation of p38 by TGF-β-activated Kinase 1 and Mitogen-activated Protein Kinase Kinase 32.5222Citations (PDF)
308Transforming Growth Factor-β1 Mutations in Camurati-Engelmann Disease Lead to Increased Signaling by Altering either Activation or Secretion of the Mutant Protein
Journal of Biological Chemistry, 2003, 278, 7718-7724
2.2108Citations (PDF)
309dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development
Journal of Biological Chemistry, 2003, 278, 26307-26310
2.246Citations (PDF)
310Smad protein and TGF-β signaling in vascular smooth muscle cells4.512Citations (PDF)
311Growth Differentiation Factor-9 Induces Smad2 Activation and Inhibin B Production in Cultured Human Granulosa-Luteal Cells4.2115Citations (PDF)
312SIGNAL TRANSDUCTION OF BONE MORPHOGENETIC PROTEINS IN OSTEOBLAST DIFFERENTIATION3.492Citations (PDF)
313Transient Disruption of Autocrine TGF-β Signaling Leads to Enhanced Survival and Proliferation Potential in Single Primitive Human Hemopoietic Progenitor Cells
Journal of Immunology, 2002, 168, 755-762
0.646Citations (PDF)
314Stimulation of Id1 Expression by Bone Morphogenetic Protein Is Sufficient and Necessary for Bone Morphogenetic Protein–Induced Activation of Endothelial Cells
Circulation, 2002, 106, 2263-2270
25.2286Citations (PDF)
315Deficient Smad7 expression: A putative molecular defect in scleroderma7.6232Citations (PDF)
316Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter
Journal of Biological Chemistry, 2002, 277, 4883-4891
2.2811Citations (PDF)
317Immunohistochemical Localization of Osteogenetic Protein (OP-1) and Its Receptors in Rabbit Articular Cartilage1.520Citations (PDF)
318Activation of Bone Morphogenetic Protein/Smad Signaling in Bronchial Epithelial Cells during Airway Inflammation4.3121Citations (PDF)
319BMP Pathways Are Involved in Otic Capsule Formation and Epithelial–Mesenchymal Signaling in the Developing Chicken Inner Ear
Developmental Biology, 2002, 251, 380-394
1.983Citations (PDF)
320Engagement of activin and bone morphogenetic protein signaling pathway Smad proteins in the induction of inhibin B production in ovarian granulosa cells3.523Citations (PDF)
321Physical and Functional Interaction between GATA-3 and Smad3 Allows TGF-β Regulation of GATA Target Genes
Current Biology, 2002, 12, 35-45
3.692Citations (PDF)
322Action Range of BMP Is Defined by Its N-Terminal Basic Amino Acid Core
Current Biology, 2002, 12, 205-209
3.6166Citations (PDF)
323Regulation of cell proliferation by Smad proteins4.2427Citations (PDF)
324The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF‐β/Smad signalling
Genes To Cells, 2002, 7, 321-331
1.5142Citations (PDF)
325Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues
EMBO Journal, 2002, 21, 2580-2590
7.4102Citations (PDF)
326Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
EMBO Journal, 2002, 21, 1743-1753
7.41,023Citations (PDF)
327Diffusion of Nodal Signaling Activity in the Absence of the Feedback Inhibitor Lefty2
Developmental Cell, 2001, 1, 127-138
7.8120Citations (PDF)
328Transforming growth factor β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts
FEBS Letters, 2001, 502, 4-10
2.7187Citations (PDF)
329Ectopic expression of Smad7 inhibits transforming growth factor-β responses in vascular smooth muscle cells
Life Sciences, 2001, 69, 2641-2652
4.713Citations (PDF)
330Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells
Journal of Cellular Physiology, 2001, 187, 117-123
4.2112Citations (PDF)
331Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
EMBO Journal, 2001, 20, 4132-4142
7.4168Citations (PDF)
332Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice
EMBO Journal, 2001, 20, 1663-1673
7.4523Citations (PDF)
333Transforming growth factor-β-mediated mast cell migration depends on mitogen-activated protein kinase activity
Cellular Signalling, 2001, 13, 483-490
3.655Citations (PDF)
334Nodal Signaling Uses Activin and Transforming Growth Factor-β Receptor-regulated Smads2.2107Citations (PDF)
335The Orphan Receptor Serine/Threonine Kinase ALK7 Signals Arrest of Proliferation and Morphological Differentiation in a Neuronal Cell Line
Journal of Biological Chemistry, 2001, 276, 5140-5146
2.252Citations (PDF)
336Interaction between GC Box Binding Factors and Smad Proteins Modulates Cell Lineage-specific α2(I) Collagen Gene Transcription
Journal of Biological Chemistry, 2001, 276, 16573-16579
2.275Citations (PDF)
337Activation of the TGF- β /Activin-Smad2 Pathway during Allergic Airway Inflammation4.3124Citations (PDF)
338Apoptosis in podocytes induced by TGF-β and Smad710.7259Citations (PDF)
339Apoptosis in podocytes induced by TGF-β and Smad710.7556Citations (PDF)
340Human mast cell migration in response to members of the transforming growth factor-β family
Journal of Leukocyte Biology, 2000, 67, 350-356
3.0114Citations (PDF)
341Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis
Developmental Dynamics, 2000, 218, 663-670
1.820Citations (PDF)
342Signaling of transforming growth factor‐β family members through Smad proteins
FEBS Journal, 2000, 267, 6954-6967
0.2481Citations (PDF)
343Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4
Oncogene, 2000, 19, 4396-4404
6.787Citations (PDF)
344Smad7 mediates apoptosis induced by transforming growth factor β in prostatic carcinoma cells
Current Biology, 2000, 10, 535-538
3.6151Citations (PDF)
345Signaling inputs converge on nuclear effectors in TGF-β signaling6.7343Citations (PDF)
346Efficient TGF-β Induction of the Smad7 Gene Requires Cooperation between AP-1, Sp1, and Smad Proteins on the Mouse Smad7 Promoter
Journal of Biological Chemistry, 2000, 275, 29023-29030
2.2147Citations (PDF)
347Role of Smad Proteins and Transcription Factor Sp1 in p21Waf1/Cip1 Regulation by Transforming Growth Factor-β
Journal of Biological Chemistry, 2000, 275, 29244-29256
2.2359Citations (PDF)
348Smad and AML Proteins Synergistically Confer Transforming Growth Factor β1 Responsiveness to Human Germ-line IgA Genes
Journal of Biological Chemistry, 2000, 275, 3552-3560
2.2139Citations (PDF)
349The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling
Nucleic Acids Research, 2000, 28, 4291-4298
15.7103Citations (PDF)
350Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis7.6821Citations (PDF)
351Hedgehog Creates a Gradient of DPP Activity in Drosophila Wing Imaginal Discs
Molecular Cell, 2000, 5, 59-71
13.4403Citations (PDF)
352Correlation between ALK-6 (BMPR-IB) Distribution and Responsiveness to Osteogenic Protein-1 (BMP-7) in Embryonic Mouse Bone Rudiments
Growth Factors, 2000, 17, 177-192
1.821Citations (PDF)
353TGF-β signaling by Smad proteins
Advances in Immunology, 2000, , 115-157
7.1425Citations (PDF)
354Specificity, diversity, and regulation in TGF‐β superfamily signaling
FASEB Journal, 1999, 13, 2105-2124
0.7734Citations (PDF)
355Expression of TGF-beta related Smad proteins in human epithelial skin tumors.4.017Citations (PDF)
356Expression of Transforming Growth Factor-β1, Activin A, and Their Receptors in Thyroid Follicle Cells: Negative Regulation of Thyrocyte Growth and Function1
Endocrinology, 1999, 140, 4300-4310
2.655Citations (PDF)
357Eccrine Sweat Glands: Expression of Transforming Growth Factor-beta and Bone Morphogenetic Protein Type I Receptors and Their Intracellular Signalling Smad Proteins
Acta Dermato-Venereologica, 1999, 79, 183-186
1.95Citations (PDF)
358Differential Inhibition of Smad6 and Smad7 on Bone Morphogenetic Protein- and Activin-mediated Growth Arrest and Apoptosis in B Cells
Journal of Biological Chemistry, 1999, 274, 13637-13642
2.2206Citations (PDF)
359Localization of Smads, the TGF-β Family Intracellular Signaling Components During Endochondral Ossification5.0145Citations (PDF)
360Chromosomal localization of three human genes encoding bone morphogenetic protein receptors
Mammalian Genome, 1999, 10, 299-302
2.314Citations (PDF)
361Functional antagonism between activin and osteogenic protein-1 in human embryonal carcinoma cells
1999, 180, 141-149
43Citations (PDF)
362Molecular analyses of the 15q and 18qSMAD genes in pancreatic cancer
1999, 24, 62-71
54Citations (PDF)
363Expression of transforming-growth-factor (TGF)-? receptors and Smad proteins in glioblastoma cell lines with distinct responses to TGF-?1
1999, 80, 756-763
74Citations (PDF)
364Expression of Smad proteins in human colorectal cancer4.5100Citations (PDF)
365Lack of responsiveness to TGF-β1 in a thyroid carcinoma cell line with functional type I and type II TGF-β receptors and Smad proteins, suggests a novel mechanism for TGF-β insensitivity in carcinoma cells3.526Citations (PDF)
366Xenopus Smad4β Is the Co-Smad Component of Developmentally Regulated Transcription Factor Complexes Responsible for Induction of Early Mesodermal Genes
Developmental Biology, 1999, 214, 354-369
1.989Citations (PDF)
367Expression of Transforming Growth Factor- 1, Activin A, and Their Receptors in Thyroid Follicle Cells: Negative Regulation of Thyrocyte Growth and Function
Endocrinology, 1999, 140, 4300-4310
2.615Citations (PDF)
368Cartilage-Derived Morphogenetic Proteins and Osteogenic Protein-1 Differentially Regulate Osteogenesis5.0146Citations (PDF)
369Direct binding of Smad3 and Smad4 to critical TGFbeta -inducible elements in the promoter of human plasminogen activator inhibitor-type 1gene
EMBO Journal, 1998, 17, 3091-3100
7.41,692Citations (PDF)
370Intracellular signaling of osteogenic protein-1 through Smad5 activation
1998, 177, 355-363
74Citations (PDF)
371Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat2.532Citations (PDF)
372Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line
Genes To Cells, 1998, 3, 125-134
1.570Citations (PDF)
373Distinct and Overlapping Patterns of Localization of Bone Morphogenetic Protein (BMP) Family Members and a BMP Type II Receptor During Fracture Healing in Rats
Bone, 1998, 22, 605-612
3.6266Citations (PDF)
374The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation
FEBS Letters, 1998, 434, 83-87
2.7360Citations (PDF)
375Induction of Inhibitory Smad6 and Smad7 mRNA by TGF-β Family Members2.1336Citations (PDF)
376Cloning and Characterization of p70S6KβDefines a Novel Family of p70 S6 Kinases2.151Citations (PDF)
377Smad7 Is an Activin-inducible Inhibitor of Activin-induced Growth Arrest and Apoptosis in Mouse B Cells
Journal of Biological Chemistry, 1998, 273, 24293-24296
2.2120Citations (PDF)
378Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer
Journal of Biological Chemistry, 1998, 273, 21145-21152
2.2530Citations (PDF)
379Transforming Growth Factor β1 Induces Nuclear Export of Inhibitory Smad7
Journal of Biological Chemistry, 1998, 273, 29195-29201
2.2220Citations (PDF)
380Physical and Functional Interaction of Murine and Xenopus Smad7 with Bone Morphogenetic Protein Receptors and Transforming Growth Factor-β Receptors
Journal of Biological Chemistry, 1998, 273, 25364-25370
2.2146Citations (PDF)
381Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling
Journal of Biological Chemistry, 1997, 272, 28107-28115
2.2359Citations (PDF)
382Transforming Growth Factor (TGF-β)-specific Signaling by Chimeric TGF-β Type II Receptor with Intracellular Domain of Activin Type IIB Receptor
Journal of Biological Chemistry, 1997, 272, 21187-21194
2.232Citations (PDF)
383Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor β Signaling Pathway
Journal of Biological Chemistry, 1997, 272, 2896-2900
2.2155Citations (PDF)
384Latent transforming growth factor-<i>β</i> complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160
Biochemical Journal, 1997, 324, 427-434
3.928Citations (PDF)
385Expression and localization of bone morphogenetic proteins (BMPs) and BMP receptors in ossification of the ligamentum flavum
Bone, 1997, 21, 23-30
3.6102Citations (PDF)
386DPC4 (SMAD4) mediates transforming growth factor-β1 (TGF-β1) induced growth inhibition and transcriptional response in breast tumour cells
Oncogene, 1997, 14, 1891-1899
6.7132Citations (PDF)
387TGF-β signalling from cell membrane to nucleus through SMAD proteins
Nature, 1997, 390, 465-471
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388TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
EMBO Journal, 1997, 16, 5353-5362
7.4996Citations (PDF)
389Orthotopic ossification of the spinal ligaments of zucker fatty rats: A possible animal model for ossification of the human posterior longitudinal ligament2.523Citations (PDF)
390Characterization of a 60-kDa cell surface-associated transforming growth factor-β binding protein that can interfere with transforming growth factor-β receptor binding
Journal of Cellular Physiology, 1997, 173, 447-459
4.224Citations (PDF)
391Bone morphogenetic protein receptors
Bone, 1996, 19, 569-574
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392Follistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors3.5186Citations (PDF)
393Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors3.9254Citations (PDF)
394Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours
British Journal of Cancer, 1996, 73, 624-629
5.733Citations (PDF)
395A Novel Type I Receptor Serine-Threonine Kinase Predominantly Expressed in the Adult Central Nervous System
Journal of Biological Chemistry, 1996, 271, 30603-30609
2.270Citations (PDF)
396Cloning and characterization of a human type II receptor for bone morphogenetic proteins.7.6515Citations (PDF)
397A Rat Pituitary Tumor Cell Line (GH3 ) Expresses Type I and Type II Receptors and Other Cell Surface Binding Protein(s) for Transforming Growth Factor- β2.222Citations (PDF)
398Efficient Association of an Amino-terminally Extended Form of Human Latent Transforming Growth Factor-β Binding Protein with the Extracellular Matrix
Journal of Biological Chemistry, 1995, 270, 31294-31297
2.281Citations (PDF)
399Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis
Mechanisms of Development, 1995, 52, 109-123
2.6111Citations (PDF)
400Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis
Endocrinology, 1995, 136, 2652-2663
2.681Citations (PDF)
401Serine/threonine kinase receptors1.272Citations (PDF)
402Characterization of in Vivo Phosphorylation of Activin Type II Receptor2.119Citations (PDF)
403Regulation of the levels of three transforming growth factor β mRNAs by estrogen and their effects on the proliferation of human breast cancer cells3.551Citations (PDF)
404Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor
Cell, 1993, 75, 681-692
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405Molecular Characterization of Transforming Growth Factor Type ?34.134Citations (PDF)
406Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms
Journal of Biological Chemistry, 1990, 265, 20533-20538
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407Growth Factors For Wound Healing
Nature Biotechnology, 1989, 7, 793-798
32.264Citations (PDF)
408Identification of another member of the transforming growth factor type beta gene family.7.6295Citations (PDF)
409Genomic characterization of the human DNA excision repair geneERCC-1
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15.773Citations (PDF)