| 1 | A subgroup of light-driven sodium pumps with an additional Schiff base counterion | 13.9 | 13 | Citations (PDF) |
| 2 | EMBL’s European Bioinformatics Institute (EMBL-EBI) in 2022 | 15.7 | 42 | Citations (PDF) |
| 3 | Database Commons: A Catalog of Worldwide Biological Databases | 6.2 | 59 | Citations (PDF) |
| 4 | The Gene Ontology knowledgebase in 2023 | 4.2 | 1,940 | Citations (PDF) |
| 5 | Nightingale: web components for protein feature visualization | 2.4 | 8 | Citations (PDF) |
| 6 | Uncovering new families and folds in the natural protein universe | 38.7 | 141 | Citations (PDF) |
| 7 | Expanding the repertoire of human tandem repeat RNA-binding proteins | 2.4 | 1 | Citations (PDF) |
| 8 | When will RNA get its AlphaFold moment? | 15.7 | 99 | Citations (PDF) |
| 9 | MBDBMetrics: an online metrics tool to measure the impact of biological data resources | 2.4 | 1 | Citations (PDF) |
| 10 | The European Bioinformatics Institute (EMBL-EBI) in 2021 | 15.7 | 69 | Citations (PDF) |
| 11 | Folding the unfoldable: using AlphaFold to explore spurious proteins | 2.4 | 50 | Citations (PDF) |
| 12 | Using deep learning to annotate the protein universe | 32.2 | 281 | Citations (PDF) |
| 13 | Large-Scale Discovery of Microbial Fibrillar Adhesins and Identification of Novel Members of Adhesive Domain Families | 2.9 | 16 | Citations (PDF) |
| 14 | Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems | 38.7 | 133 | Citations (PDF) |
| 15 | A roadmap for the functional annotation of protein families: a community perspective | 2.8 | 49 | Citations (PDF) |
| 16 | DPCfam: Unsupervised protein family classification by Density Peak Clustering of large sequence datasets | 3.1 | 7 | Citations (PDF) |
| 17 | InterPro in 2022 | 15.7 | 2,300 | Citations (PDF) |
| 18 | A structural biology community assessment of AlphaFold2 applications | 8.7 | 562 | Citations (PDF) |
| 19 | Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research | 6.7 | 129 | Citations (PDF) |
| 20 | The InterPro protein families and domains database: 20 years on | 15.7 | 2,076 | Citations (PDF) |
| 21 | Rfam 14: expanded coverage of metagenomic, viral and microRNA families | 15.7 | 953 | Citations (PDF) |
| 22 | UniProt: the universal protein knowledgebase in 2021 | 15.7 | 6,135 | Citations (PDF) |
| 23 | Pfam: The protein families database in 2021 | 15.7 | 5,796 | Citations (PDF) |
| 24 | How to use the <scp><i>MEROPS</i></scp> database and website to help understand peptidase specificity | 6.0 | 76 | Citations (PDF) |
| 25 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states | 8.7 | 89 | Citations (PDF) |
| 26 | Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes | 6.7 | 56 | Citations (PDF) |
| 27 | Periscope Proteins are variable-length regulators of bacterial cell surface interactions | 7.6 | 20 | Citations (PDF) |
| 28 | Highly accurate protein structure prediction for the human proteome | 38.7 | 2,845 | Citations (PDF) |
| 29 | Discovery of fibrillar adhesins across bacterial species | 3.3 | 20 | Citations (PDF) |
| 30 | The Gene Ontology resource: enriching a GOld mine | 15.7 | 3,261 | Citations (PDF) |
| 31 | <i>Caenorhabditis elegans</i> AF4/FMR2 Family Homolog <i>affl-2</i> Regulates Heat-Shock-Induced Gene Expression | 4.2 | 6 | Citations (PDF) |
| 32 | Acetylation of Surface Carbohydrates in Bacterial Pathogens Requires Coordinated Action of a Two-Domain Membrane-Bound Acyltransferase | 4.4 | 30 | Citations (PDF) |
| 33 | The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences | 4.8 | 66 | Citations (PDF) |
| 34 | The thrombospondin module 1 domain of the matricellular protein CCN3 shows an atypical disulfide pattern and incomplete CWR layers | 3.2 | 7 | Citations (PDF) |
| 35 | Modelling structural rearrangements in proteins using Euclidean distance matrices | 0.5 | 1 | Citations (PDF) |
| 36 | Origins of peptidases | 2.9 | 42 | Citations (PDF) |
| 37 | Tandem domain swapping: determinants of multidomain protein misfolding | 6.4 | 41 | Citations (PDF) |
| 38 | Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases | 15.7 | 330 | Citations (PDF) |
| 39 | Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection | 7.6 | 23 | Citations (PDF) |
| 40 | RNAcentral: a hub of information for non-coding RNA sequences | 15.7 | 70 | Citations (PDF) |
| 41 | TADOSS: computational estimation of tandem domain swap stability | 4.8 | 8 | Citations (PDF) |
| 42 | RNAcentral: a hub of information for non-coding RNA sequences | 15.7 | 251 | Citations (PDF) |
| 43 | The Pfam protein families database in 2019 | 15.7 | 4,527 | Citations (PDF) |
| 44 | Rfam 13.0: shifting to a genome-centric resource for non-coding RNA families | 15.7 | 956 | Citations (PDF) |
| 45 | The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database | 15.7 | 1,621 | Citations (PDF) |
| 46 | Non‐Coding RNA Analysis Using the Rfam Database | 3.3 | 455 | Citations (PDF) |
| 47 | Gene Unprediction with Spurio: A tool to identify spurious protein sequences | 0.5 | 11 | Citations (PDF) |
| 48 | Rapid identification of novel protein families using similarity searches | 0.5 | 3 | Citations (PDF) |
| 49 | Structure of the <i>Escherichia coli</i> ProQ RNA-binding protein | 3.8 | 60 | Citations (PDF) |
| 50 | InterPro in 2017—beyond protein family and domain annotations | 15.7 | 1,506 | Citations (PDF) |
| 51 | The yeast noncoding RNA interaction network | 3.8 | 26 | Citations (PDF) |
| 52 | The HMMER Web Server for Protein Sequence Similarity Search | 3.3 | 187 | Citations (PDF) |
| 53 | RNAcentral: a comprehensive database of non-coding RNA
sequences | 15.7 | 237 | Citations (PDF) |
| 54 | Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources | 0.5 | 16 | Citations (PDF) |
| 55 | UniProt-DAAC: domain architecture alignment and classification, a new method for automatic functional annotation in UniProtKB | 4.8 | 43 | Citations (PDF) |
| 56 | The Pfam protein families database: towards a more sustainable future | 15.7 | 6,008 | Citations (PDF) |
| 57 | Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat: Figure 1. | 2.8 | 8 | Citations (PDF) |
| 58 | The Importance of Biological Databases in Biological Discovery | 3.3 | 51 | Citations (PDF) |
| 59 | HMMER web server: 2015 update | 15.7 | 977 | Citations (PDF) |
| 60 | The InterPro protein families database: the classification resource after 15 years | 15.7 | 1,313 | Citations (PDF) |
| 61 | Domain atrophy creates rare cases of functional partial protein domains | 12.8 | 26 | Citations (PDF) |
| 62 | RNAcentral: an international database of ncRNA sequences | 15.7 | 119 | Citations (PDF) |
| 63 | Rfam 12.0: updates to the RNA families database | 15.7 | 1,125 | Citations (PDF) |
| 64 | iPfam: a database of protein family and domain interactions found in the Protein Data Bank | 15.7 | 169 | Citations (PDF) |
| 65 | Using the MEROPS Database for Proteolytic Enzymes and Their Inhibitors and Substrates | 3.3 | 47 | Citations (PDF) |
| 66 | TreeFam v9: a new website, more species and orthology-on-the-fly | 15.7 | 134 | Citations (PDF) |
| 67 | Pfam: the protein families database | 15.7 | 6,075 | Citations (PDF) |
| 68 | Structure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix domains reveals a possible role in modified polysaccharide biosynthesis | 3.0 | 1 | Citations (PDF) |
| 69 | <i>MEROPS</i>: the database of proteolytic enzymes, their substrates and inhibitors | 15.7 | 892 | Citations (PDF) |
| 70 | Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila | 3.0 | 3 | Citations (PDF) |
| 71 | Alternative splicing of intrinsically disordered regions and rewiring of protein interactions | 6.4 | 175 | Citations (PDF) |
| 72 | Filling out the structural map of the NTF2-like superfamily | 3.0 | 90 | Citations (PDF) |
| 73 | LUD, a new protein domain associated with lactate utilization | 3.0 | 18 | Citations (PDF) |
| 74 | The COMBREX Project: Design, Methodology, and Initial Results | 5.0 | 55 | Citations (PDF) |
| 75 | ISCB Computational Biology Wikipedia Competition | 3.1 | 10 | Citations (PDF) |
| 76 | Rfam 11.0: 10 years of RNA families | 15.7 | 781 | Citations (PDF) |
| 77 | Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling | 8.2 | 332 | Citations (PDF) |
| 78 | A comparison of dense transposon insertion libraries in the Salmonella serovars Typhi and Typhimurium | 15.7 | 121 | Citations (PDF) |
| 79 | The challenge of increasing Pfam coverage of the human proteome | 2.8 | 24 | Citations (PDF) |
| 80 | DATABASE, The Journal of Biological Databases and Curation, is now the official journal of the International Society for Biocuration | 2.8 | 1 | Citations (PDF) |
| 81 | Challenges in homology search: HMMER3 and convergent evolution of coiled-coil regions | 15.7 | 1,573 | Citations (PDF) |
| 82 | The SHOCT Domain: A Widespread Domain Under-Represented in Model Organisms | 2.4 | 7 | Citations (PDF) |
| 83 | Biocurators and Biocuration: surveying the 21st century challenges | 2.8 | 68 | Citations (PDF) |
| 84 | AntiFam: a tool to help identify spurious ORFs in protein annotation | 2.8 | 59 | Citations (PDF) |
| 85 | Bioimage informatics: a new category in <i>Bioinformatics</i> | 4.8 | 29 | Citations (PDF) |
| 86 | The Pfam protein families database | 15.7 | 3,467 | Citations (PDF) |
| 87 | Recent advances in biocuration: Meeting Report from the fifth International Biocuration Conference | 2.8 | 10 | Citations (PDF) |
| 88 | Making your database available through Wikipedia: the pros and cons | 15.7 | 31 | Citations (PDF) |
| 89 | InterPro in 2011: new developments in the family and domain prediction database | 15.7 | 956 | Citations (PDF) |
| 90 | Tissue-Specific Splicing of Disordered Segments that Embed Binding Motifs Rewires Protein Interaction Networks | 13.4 | 373 | Citations (PDF) |
| 91 | MEROPS: the database of proteolytic enzymes, their substrates and inhibitors | 15.7 | 1,094 | Citations (PDF) |
| 92 | The YARHG Domain: An Extracellular Domain in Search of a Function | 2.4 | 4 | Citations (PDF) |
| 93 | The Characterisation of Three Types of Genes that Overlie Copy Number Variable Regions | 2.4 | 26 | Citations (PDF) |
| 94 | Towards BioDBcore: a community-defined information specification for biological databases | 2.8 | 32 | Citations (PDF) |
| 95 | RNIE: genome-wide prediction of bacterial intrinsic terminators | 15.7 | 88 | Citations (PDF) |
| 96 | Rfam: Wikipedia, clans and the "decimal" release | 15.7 | 361 | Citations (PDF) |
| 97 | Towards BioDBcore: a community-defined information specification for biological databases | 15.7 | 33 | Citations (PDF) |
| 98 | RNAcentral: A vision for an international database of RNA sequences | 3.8 | 74 | Citations (PDF) |
| 99 | Asparagine Peptide Lyases | 2.2 | 95 | Citations (PDF) |
| 100 | The rise and fall of supervised machine learning techniques | 4.8 | 32 | Citations (PDF) |
| 101 | The structure of Jann_2411 (DUF1470) from<i>Jannaschia</i>sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator | 0.7 | 11 | Citations (PDF) |
| 102 | DUFs: families in search of function | 0.7 | 233 | Citations (PDF) |
| 103 | SnoPatrol: how many snoRNA genes are there? | 1.7 | 37 | Citations (PDF) |
| 104 | Dosage Sensitivity Shapes the Evolution of Copy-Number Varied Regions | 2.4 | 91 | Citations (PDF) |
| 105 | Curators of the world unite: the International Society of Biocuration | 4.8 | 42 | Citations (PDF) |
| 106 | MEROPS: the peptidase database | 15.7 | 864 | Citations (PDF) |
| 107 | Bacterial Pleckstrin Homology Domains: A Prokaryotic Origin for the PH Domain | 4.2 | 36 | Citations (PDF) |
| 108 | The Systematic Functional Analysis of Plasmodium Protein Kinases Identifies Essential Regulators of Mosquito Transmission | 15.3 | 301 | Citations (PDF) |
| 109 | Quantifying the mechanisms of domain gain in animal proteins | 8.2 | 99 | Citations (PDF) |
| 110 | The Pfam protein families database | 15.7 | 2,760 | Citations (PDF) |
| 111 | Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane tethered transcription factors | 4.8 | 72 | Citations (PDF) |
| 112 | InterPro: the integrative protein signature database | 15.7 | 1,915 | Citations (PDF) |
| 113 | Rfam: updates to the RNA families database | 15.7 | 882 | Citations (PDF) |
| 114 | Pepsin homologues in bacteria | 3.3 | 36 | Citations (PDF) |
| 115 | The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes | 1.8 | 6 | Citations (PDF) |
| 116 | Cloud computing | 4.8 | 57 | Citations (PDF) |
| 117 | Protein interactions in human genetic diseases | 12.8 | 113 | Citations (PDF) |
| 118 | Large-scale screening for novel low-affinity extracellular protein interactions | 4.6 | 205 | Citations (PDF) |
| 119 | Pfam 10 years on: 10 000 families and still growing | 6.7 | 117 | Citations (PDF) |
| 120 | The RNA WikiProject: Community annotation of RNA families | 3.8 | 68 | Citations (PDF) |
| 121 | Identifying Protein Domains with the Pfam Database | 3.3 | 63 | Citations (PDF) |
| 122 | Databases, data tombs and dust in the wind | 4.8 | 43 | Citations (PDF) |
| 123 | New developments in the InterPro database | 15.7 | 450 | Citations (PDF) |
| 124 | SCOOP: a simple method for identification of novel protein superfamily relationships | 4.8 | 49 | Citations (PDF) |
| 125 | The Pfam protein families database | 15.7 | 6,627 | Citations (PDF) |
| 126 | Reuse of structural domain–domain interactions in protein networks | 3.0 | 44 | Citations (PDF) |
| 127 | Predicting active site residue annotations in the Pfam database | 3.0 | 311 | Citations (PDF) |
| 128 | miRBase: microRNA sequences, targets and gene nomenclature | 15.7 | 4,471 | Citations (PDF) |
| 129 | Bioinformatics--The new home for protein sequence motifs | 4.8 | 4 | Citations (PDF) |
| 130 | Pfam: clans, web tools and services | 15.7 | 2,124 | Citations (PDF) |
| 131 | Software patents in Bioinformatics | 4.8 | 1 | Citations (PDF) |
| 132 | Structural genomics meets computational biology | 4.8 | 6 | Citations (PDF) |
| 133 | Metazoan Scc4 Homologs Link Sister Chromatid Cohesion to Cell and Axon Migration Guidance | 5.0 | 98 | Citations (PDF) |
| 134 | Rfam: annotating non-coding RNAs in complete genomes | 15.7 | 1,477 | Citations (PDF) |
| 135 | Visualizing profile-profile alignment: pairwise HMM logos | 4.8 | 35 | Citations (PDF) |
| 136 | iPfam: visualization of protein-protein interactions in PDB at domain and amino acid resolutions | 4.8 | 296 | Citations (PDF) |
| 137 | The G5 domain: a potential N-acetylglucosamine recognition domain involved in biofilm formation | 4.8 | 87 | Citations (PDF) |
| 138 | INCREASING THE IMPACT OF BIOINFORMATICS | 4.8 | 37 | Citations (PDF) |
| 139 | An update from the Bioinformatics Editors | 4.8 | 0 | Citations (PDF) |
| 140 | InterPro, progress and status in 2005 | 15.7 | 480 | Citations (PDF) |
| 141 | New Leadership for Bioinformatics | 4.8 | 2 | Citations (PDF) |
| 142 | Novel protein domains and motifs in the marine planctomycete Rhodopirellula baltica | 1.9 | 24 | Citations (PDF) |
| 143 | The PepSY domain: a regulator of peptidase activity in the microbial environment? | 6.7 | 85 | Citations (PDF) |
| 144 | Title is missing! | 3.0 | 165 | Citations (PDF) |
| 145 | Title is missing! | 3.0 | 18 | Citations (PDF) |
| 146 | The Pfam protein families database | 15.7 | 3,291 | Citations (PDF) |
| 147 | The CHAP domain: a large family of amidases including GSP amidase and peptidoglycan hydrolases | 6.7 | 232 | Citations (PDF) |
| 148 | The BON domain: a putative membrane-binding domain | 6.7 | 96 | Citations (PDF) |
| 149 | Title is missing! | 3.0 | 8 | Citations (PDF) |
| 150 | Title is missing! | 3.0 | 30 | Citations (PDF) |
| 151 | Title is missing! | 3.9 | 109 | Citations (PDF) |
| 152 | Identifying Protein Domains with the Pfam Database | 3.3 | 27 | Citations (PDF) |
| 153 | Rfam: an RNA family database | 15.7 | 1,441 | Citations (PDF) |
| 154 | The InterPro Database, 2003 brings increased coverage and new features | 15.7 | 639 | Citations (PDF) |
| 155 | Enhanced protein domain discovery by using language modeling techniques from speech recognition | 7.6 | 50 | Citations (PDF) |
| 156 | HMM-based databases in InterPro | 6.7 | 30 | Citations (PDF) |
| 157 | InterPro: An integrated documentation resource for protein families, domains and functional sites | 6.7 | 164 | Citations (PDF) |
| 158 | QuickTree: building huge Neighbour-Joining trees of protein sequences | 4.8 | 283 | Citations (PDF) |
| 159 | The use of structure information to increase alignment accuracy does not aid homologue detection with profile HMMs | 4.8 | 19 | Citations (PDF) |
| 160 | Title is missing! | 12.8 | 126 | Citations (PDF) |
| 161 | The Pfam Protein Families Database | 15.7 | 2,109 | Citations (PDF) |
| 162 | The ENTH domain | 2.7 | 137 | Citations (PDF) |
| 163 | The PASTA domain: a β-lactam-binding domain | 6.7 | 220 | Citations (PDF) |
| 164 | Title is missing! | 3.0 | 31 | Citations (PDF) |
| 165 | Mining the draft human genome | 38.7 | 59 | Citations (PDF) |
| 166 | Initial sequencing and analysis of the human genome | 38.7 | 22,433 | Citations (PDF) |
| 167 | Searching databases to find protein domain organization | 5.2 | 18 | Citations (PDF) |
| 168 | Domains in gene silencing and cell differentiation proteins: the novel PAZ domain and redefinition of the Piwi domain | 6.7 | 390 | Citations (PDF) |
| 169 | The PA domain: A protease‐associated domain | 6.0 | 97 | Citations (PDF) |
| 170 | The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD) 1 1Edited by P. E. Wight | 4.2 | 423 | Citations (PDF) |
| 171 | The Pfam Protein Families Database | 15.7 | 1,201 | Citations (PDF) |
| 172 | Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins | 15.7 | 541 | Citations (PDF) |
| 173 | The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease | 7.4 | 197 | Citations (PDF) |
| 174 | The PLAT domain: a new piece in the PKD1 puzzle | 3.6 | 134 | Citations (PDF) |
| 175 | The SIS domain: a phosphosugar-binding domain | 6.7 | 86 | Citations (PDF) |
| 176 | Structure and distribution of pentapeptide repeats in bacteria | 6.0 | 94 | Citations (PDF) |
| 177 | TheDUTT1Gene, a Novel NCAM Family Member Is Expressed in Developing Murine Neural Tissues and Has an Unusually Broad Pattern of Expression | 2.2 | 69 | Citations (PDF) |
| 178 | Pfam: multiple sequence alignments and HMM-profiles of protein domains | 15.7 | 677 | Citations (PDF) |
| 179 | Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains | 3.0 | 146 | Citations (PDF) |
| 180 | The structure of a domain common to archaebacteria and the homocystinuria disease protein | 6.7 | 476 | Citations (PDF) |
| 181 | Title is missing! | 1.9 | 29 | Citations (PDF) |
| 182 | Distant homology recognition using structural classification of proteins 1997, 29, 105-112 | | 41 | Citations (PDF) |
| 183 | Members of the immunoglobulin superfamily in bacteria | 6.0 | 68 | Citations (PDF) |
| 184 | EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling | 1.6 | 12 | Citations (PDF) |