| 1 | Cancer Prevalence across Vertebrates | 26.3 | 32 | Citations (PDF) |
| 2 | Germline Pathogenic
<i>DROSHA</i>
Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition | 6.4 | 3 | Citations (PDF) |
| 3 | Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | 14.2 | 29 | Citations (PDF) |
| 4 | Heritable defects in telomere and mitotic function selectively predispose to sarcomas | 19.5 | 36 | Citations (PDF) |
| 5 | Li–Fraumeni Syndrome–Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death | 26.3 | 18 | Citations (PDF) |
| 6 | Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome | 3.0 | 11 | Citations (PDF) |
| 7 | Evolutionary determinants of curability in cancer | 10.7 | 10 | Citations (PDF) |
| 8 | Inherited TP53 Variants and Risk of Prostate Cancer | 1.4 | 73 | Citations (PDF) |
| 9 | Automated Clinical Practice Guideline Recommendations for Hereditary Cancer Risk Using Chatbots and Ontologies: System Description | 2.8 | 16 | Citations (PDF) |
| 10 | Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes | 6.5 | 42 | Citations (PDF) |
| 11 | Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition | 1.1 | 5 | Citations (PDF) |
| 12 | Of Elephants and Other Mammals: A Comparative Review of Reproductive Tumors and Potential Impact on Conservation | 2.3 | 2 | Citations (PDF) |
| 13 | COVID-19 and Sepsis Are Associated With Different Abnormalities in Plasma Procoagulant and Fibrinolytic Activity | 5.4 | 122 | Citations (PDF) |
| 14 | A thematic analysis of health information technology use among cancer genetic counselors | 1.9 | 2 | Citations (PDF) |
| 15 | Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma | 3.2 | 36 | Citations (PDF) |
| 16 | Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells | 2.5 | 5 | Citations (PDF) |
| 17 | Lung Cancer in Li-Fraumeni Syndrome | 3.2 | 5 | Citations (PDF) |
| 18 | Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses | 4.7 | 55 | Citations (PDF) |
| 19 | Comparative international incidence of Ewing sarcoma 1988 to 2012 | 4.5 | 34 | Citations (PDF) |
| 20 | Effective variant filtering and expected candidate variant yield in studies of rare human disease | 4.5 | 96 | Citations (PDF) |
| 21 | Evaluation and comparison of hereditary Cancer guidelines in the population | 1.8 | 7 | Citations (PDF) |
| 22 | Association of Combined Focal 22q11.22 Deletion and <i>IKZF1</i> Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia | 8.6 | 14 | Citations (PDF) |
| 23 | Analysis of the Li-Fraumeni Spectrum Based on an International Germline <i>TP53</i> Variant Data Set | 8.6 | 117 | Citations (PDF) |
| 24 | Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor | 3.2 | 18 | Citations (PDF) |
| 25 | Cancer therapeutics inspired by defense mechanisms in the animal kingdom | 3.3 | 9 | Citations (PDF) |
| 26 | Utilization of health information technology among cancer genetic counselors | 1.7 | 18 | Citations (PDF) |
| 27 | Cancer surveillance for individuals with Li-Fraumeni syndrome | 3.6 | 14 | Citations (PDF) |
| 28 | Using a Chatbot to Assess Hereditary Cancer Risk | 1.8 | 39 | Citations (PDF) |
| 29 | Does placental invasiveness lead to higher rates of malignant transformation in mammals? | 1.7 | 1 | Citations (PDF) |
| 30 | Suggested application of HER2+ breast tumor phenotype for germline
<i>TP53</i>
variant classification within ACMG/AMP guidelines | 4.1 | 22 | Citations (PDF) |
| 31 | Li-Fraumeni Exploration Consortium Data Coordinating Center: Building an Interactive Web-Based Resource for Collaborative International Cancer Epidemiology Research for a Rare Condition | 0.9 | 7 | Citations (PDF) |
| 32 | Lifetime cancer prevalence and life history traits in mammals | 1.7 | 86 | Citations (PDF) |
| 33 | Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndromeBlood, 2020, 136, 1169-1179 | 1.0 | 1,321 | Citations (PDF) |
| 34 | Standards-Based Clinical Decision Support Platform to Manage Patients Who Meet Guideline-Based Criteria for Genetic Evaluation of Familial Cancer | 1.8 | 43 | Citations (PDF) |
| 35 | Physicians’ strategies for using family history data: having the data is not the same as using the data | 3.0 | 21 | Citations (PDF) |
| 36 | <b>Germline Cancer Predisposition Variants in</b>
<b>Pediatric Rhabdomyosarcoma: A Report From the Children’s Oncology Group</b> | 5.2 | 93 | Citations (PDF) |
| 37 | Increased risk for other cancers in individuals with Ewing sarcoma and their relatives | 2.8 | 4 | Citations (PDF) |
| 38 | Association Between Birth Defects and Cancer Risk Among Children and Adolescents in a Population-Based Assessment of 10 Million Live Births | 8.6 | 141 | Citations (PDF) |
| 39 | Cost‐effectiveness of early cancer surveillance for patients with Li–Fraumeni syndrome | 1.5 | 28 | Citations (PDF) |
| 40 | Histone Deacetylase Inhibition Has Targeted Clinical Benefit in <i>ARID1A</i>-Mutated Advanced Urothelial Carcinoma | 1.7 | 22 | Citations (PDF) |
| 41 | The Evidence for Expanded Genetic Testing for Pediatric Patients with Cancer | 2.5 | 6 | Citations (PDF) |
| 42 | Accelerated Evolution in Distinctive Species Reveals Candidate Elements for Clinically Relevant Traits, Including Mutation and Cancer Resistance | 6.2 | 39 | Citations (PDF) |
| 43 | Evaluation of racial disparities in pediatric optic pathway glioma incidence: Results from the Surveillance, Epidemiology, and End Results Program, 2000–2014 | 2.1 | 20 | Citations (PDF) |
| 44 | Racial/ethnic disparities and incidence of malignant peripheral nerve sheath tumors: results from the Surveillance, Epidemiology, and End Results Program, 2000–2014 | 2.7 | 7 | Citations (PDF) |
| 45 | Colon Pathology Characteristics in Li–Fraumeni Syndrome | 6.1 | 9 | Citations (PDF) |
| 46 | Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors | 19.5 | 152 | Citations (PDF) |
| 47 | An overview of disparities in childhood cancer: Report on the Inaugural Symposium on Childhood Cancer Health Disparities, Houston, Texas, 2016 | 1.4 | 29 | Citations (PDF) |
| 48 | Evolution of cancer suppression as revealed by mammalian comparative genomics | 3.5 | 55 | Citations (PDF) |
| 49 | Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic | 14.2 | 69 | Citations (PDF) |
| 50 | Genomic analysis of adult B-ALL identifies potential markers of shorter survival | 0.6 | 15 | Citations (PDF) |
| 51 | Von Hippel–Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood | 6.4 | 257 | Citations (PDF) |
| 52 | Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome | 6.4 | 452 | Citations (PDF) |
| 53 | Pediatric Cancer Predisposition and Surveillance: An Overview, and a Tribute to Alfred G. Knudson Jr | 6.4 | 176 | Citations (PDF) |
| 54 | Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions | 6.4 | 100 | Citations (PDF) |
| 55 | Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues | 1.5 | 15 | Citations (PDF) |
| 56 | Classifying the evolutionary and ecological features of neoplasms | 41.2 | 388 | Citations (PDF) |
| 57 | The Future of Surveillance in the Context of Cancer Predisposition: Through the Murky Looking Glass | 6.4 | 41 | Citations (PDF) |
| 58 | Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood | 6.4 | 71 | Citations (PDF) |
| 59 | Advances in the Treatment of Pediatric Bone Sarcomas | 5.1 | 26 | Citations (PDF) |
| 60 | Melanoma risk assessment based on relatives’ age at diagnosis | 1.8 | 10 | Citations (PDF) |
| 61 | Advances in the Treatment of Pediatric Bone Sarcomas | 5.1 | 18 | Citations (PDF) |
| 62 | C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells | 1.7 | 17 | Citations (PDF) |
| 63 | Deficient Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplantation | 5.0 | 8 | Citations (PDF) |
| 64 | TP53Gene and Cancer Resistance in Elephants—Reply | 7.3 | 2 | Citations (PDF) |
| 65 | Monogenic and polygenic determinants of sarcoma risk: an international genetic study | 11.2 | 194 | Citations (PDF) |
| 66 | Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study | 11.2 | 468 | Citations (PDF) |
| 67 | Applying molecular epidemiology in pediatric leukemia | 1.7 | 4 | Citations (PDF) |
| 68 | Braddock–Carey syndrome: A 21q22 contiguous gene syndrome encompassing <i>RUNX1</i> | 1.7 | 23 | Citations (PDF) |
| 69 | 50 Years Ago in The Journal of Pediatrics | 2.0 | 0 | Citations (PDF) |
| 70 | MEK Inhibitors Reverse Growth of Embryonal Brain Tumors Derived from Oligoneural Precursor Cells | 6.2 | 42 | Citations (PDF) |
| 71 | Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database | 2.8 | 27 | Citations (PDF) |
| 72 | 10 years later: Assessing the impact of public health efforts on the collection of family health history | 1.7 | 42 | Citations (PDF) |
| 73 | Children’s Cancer and Environmental Exposures | 0.7 | 35 | Citations (PDF) |
| 74 | Early Detection of Cancer: Past, Present, and Future | 5.1 | 265 | Citations (PDF) |
| 75 | Pegasparaginase treatment alters thrombin generation by modulating the protein C and S system in acute lymphoblastic leukaemia/lymphoma | 1.1 | 9 | Citations (PDF) |
| 76 | Family Health History | 7.3 | 45 | Citations (PDF) |
| 77 | Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation | 2.5 | 26 | Citations (PDF) |
| 78 | Comparative oncology: what dogs and other species can teach us about humans with cancer | 3.9 | 331 | Citations (PDF) |
| 79 | Peto's paradox and the promise of comparative oncology | 3.9 | 72 | Citations (PDF) |
| 80 | The Cyclic AMP Pathway Is a Sex-Specific Modifier of Glioma Risk in Type I Neurofibromatosis Patients | 0.6 | 64 | Citations (PDF) |
| 81 | DNA copy number analysis of Grade II–III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status | 5.1 | 72 | Citations (PDF) |
| 82 | Parent decision‐making around the genetic testing of children for germline <i>TP53</i> mutations | 4.3 | 49 | Citations (PDF) |
| 83 | Translating genomic discoveries to the clinic in pediatric oncology | 2.5 | 30 | Citations (PDF) |
| 84 | Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans | 7.3 | 427 | Citations (PDF) |
| 85 | Genomic Analysis of Adult B-ALL Identifies Changes in Copy Number Profile at Relapse and IKZF1/CDKN2A Co-Deletion at Diagnosis As a Marker of Shorter SurvivalBlood, 2015, 126, 1427-1427 | 1.0 | 1 | Citations (PDF) |
| 86 | <i>TP53</i> intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome | 1.7 | 65 | Citations (PDF) |
| 87 | Predisposition to Pediatric and Hematologic Cancers: A Moving Target | 5.1 | 41 | Citations (PDF) |
| 88 | Clinical and Biochemical Function of Polymorphic NR0B1 GGAA-Microsatellites in Ewing Sarcoma: A Report from the Children's Oncology Group | 2.5 | 39 | Citations (PDF) |
| 89 | Pilot undergraduate course teaches students about chronic illness in children: An educational intervention study | 0.4 | 2 | Citations (PDF) |
| 90 | Molecular Inversion Probe Array for the Genetic Evaluation of Stillbirth Using Formalin-Fixed, Paraffin-Embedded Tissue | 2.8 | 16 | Citations (PDF) |
| 91 | A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia | 26.1 | 303 | Citations (PDF) |
| 92 | Familial risk of childhood cancer and tumors in the li‐fraumeni spectrum in the utah population database: Implications for genetic evaluation in pediatric practice | 4.5 | 24 | Citations (PDF) |
| 93 | Overexpression of insulin‐like growth factor 1 receptor and frequent mutational inactivation of <i>SDHA</i> in wild‐type SDHB‐negative gastrointestinal stromal tumors | 3.4 | 65 | Citations (PDF) |
| 94 | Genome-Wide Analyses of Sarcoma: Implications for Future Treatment Options | 2.5 | 0 | Citations (PDF) |
| 95 | Human Spermatogenic Failure Purges Deleterious Mutation Load from the Autosomes and Both Sex Chromosomes, including the Gene DMRT1 | 3.3 | 130 | Citations (PDF) |
| 96 | Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor | 26.3 | 314 | Citations (PDF) |
| 97 | Role of rapid sequence whole-body MRI screening in SDH-associated hereditary paraganglioma families | 1.8 | 85 | Citations (PDF) |
| 98 | Connecting Molecular Pathways to Hereditary Cancer Risk Syndromes | 5.1 | 19 | Citations (PDF) |
| 99 | Novel molecular aberrations and pathologic findings in a tubulocystic variant of renal cell carcinoma | 0.3 | 10 | Citations (PDF) |
| 100 | Differentiation of Malignant Melanoma From Benign Nevus Using a Novel Genomic Microarray With Low Specimen Requirements | 2.7 | 26 | Citations (PDF) |
| 101 | Melanoma Mimic | 1.7 | 10 | Citations (PDF) |
| 102 | <scp>TP</scp>53 pathway analysis in paediatric <scp>B</scp>urkitt lymphoma reveals increased <i><scp>MDM</scp>4</i> expression as the only <scp>TP</scp>53 pathway abnormality detected in a subset of cases | 2.5 | 24 | Citations (PDF) |
| 103 | EWS/FLI-responsive GGAA microsatellites exhibit polymorphic differences between European and African populations | 0.5 | 39 | Citations (PDF) |
| 104 | Molecular inversion probe analysis detects novel copy number alterations in Ewing sarcoma | 0.5 | 36 | Citations (PDF) |
| 105 | Molecular inversion probes: a novel microarray technology and its application in cancer research | 0.5 | 112 | Citations (PDF) |
| 106 | Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium | 0.5 | 88 | Citations (PDF) |
| 107 | The Epidemiology of Sarcoma | 2.3 | 563 | Citations (PDF) |
| 108 | Microsatellites with Macro-Influence in Ewing Sarcoma | 2.7 | 15 | Citations (PDF) |
| 109 | The Clone Wars – Revenge of the Metastatic Rogue State: The Sarcoma Paradigm | 2.7 | 12 | Citations (PDF) |
| 110 | Identification, Management, and Evaluation of Children with Cancer-Predisposition Syndromes | 5.1 | 25 | Citations (PDF) |
| 111 | PTEN Expression Is Decreased in Pediatric Burkitt Lymphoma Tissues but Does Not Correlate with AKT Activation.Blood, 2012, 120, 2664-2664 | 1.0 | 0 | Citations (PDF) |
| 112 | IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic LeukemiaBlood, 2012, 120, 289-289 | 1.0 | 4 | Citations (PDF) |
| 113 | Glutathione S-Transferases in Pediatric Cancer | 2.7 | 22 | Citations (PDF) |
| 114 | Unknown partner for USP6 and unusual SS18 rearrangement detected by fluorescence in situ hybridization in a solid aneurysmal bone cyst | 0.5 | 10 | Citations (PDF) |
| 115 | Copy number, loss of heterozygosity and amplification detection in formalin-fixed paraffin-embedded melanocytic lesions using molecular inversion probes | 0.5 | 0 | Citations (PDF) |
| 116 | FOXL2 mutation and large-scale genomic imbalances in adult granulosa cell tumors of the ovary | 0.5 | 29 | Citations (PDF) |
| 117 | Copy Number Alterations and Methylation in Ewing's Sarcoma | 1.5 | 19 | Citations (PDF) |
| 118 | Ewing's Sarcoma and Second Malignancies | 1.5 | 14 | Citations (PDF) |
| 119 | Of Mice and Men: Opportunities to Use Genetically Engineered Mouse Models of Synovial Sarcoma for Preclinical Cancer Therapeutic Evaluation | 2.4 | 9 | Citations (PDF) |
| 120 | Genome wide copy number analysis of paediatric Burkitt lymphoma using formalin‐fixed tissues reveals a subset with gain of chromosome 13q and corresponding miRNA over expression | 2.5 | 58 | Citations (PDF) |
| 121 | Childhood cancer survivorship educational resources in North American pediatric hematology/oncology fellowship training programs: A survey study | 1.5 | 13 | Citations (PDF) |
| 122 | No Child Left Behind in SDHB Testing for Paragangliomas and Pheochromocytomas | 14.2 | 14 | Citations (PDF) |
| 123 | Complex Genotype Sarcomas Display Familial Inheritance Independent of Known Cancer Predisposition Syndromes | 0.9 | 6 | Citations (PDF) |
| 124 | Focal 22q11.22 Loss Combined with IKZF1 Alterations Predict Very Poor Outcome in Childhood Acute Lymphoblastic LeukemiaBlood, 2011, 118, 741-741 | 1.0 | 0 | Citations (PDF) |
| 125 | Oncogenic <i>BRAF</i> Mutation with <i>CDKN2A</i> Inactivation Is Characteristic of a Subset of Pediatric Malignant Astrocytomas | 0.6 | 242 | Citations (PDF) |
| 126 | Succinate dehydrogenase – Assembly, regulation and role in human disease | 4.2 | 386 | Citations (PDF) |
| 127 | Toward a more uniform sampling of human genetic diversity: A survey of worldwide populations by high-density genotyping | 2.7 | 78 | Citations (PDF) |
| 128 | VPREB1 Deletions Occur Independent of Lambda-Light Chain Rearrangement and Predict Worse Outcome In Pediatric Acute Lymphoblastic Leukemia (ALL)Blood, 2010, 116, 273-273 | 1.0 | 5 | Citations (PDF) |
| 129 | T-Cell Receptor Gene Deletions Are Associated with High Risk Features and Worse Outcome In Childhood Precursor B-Cell Acute Lymphoblastic Leukemia (ALL)Blood, 2010, 116, 275-275 | 1.0 | 1 | Citations (PDF) |
| 130 | High Resolution Genome-Wide Copy Number Analysis of Pediatric Burkitt Lymphoma Identifies Copy Number Alterations In the Majority of PatientsBlood, 2010, 116, 3123-3123 | 1.0 | 0 | Citations (PDF) |
| 131 | Cross-Species Comparison of Acquired Genetic Changes In T Cell Malignancy.Blood, 2010, 116, 1192-1192 | 1.0 | 0 | Citations (PDF) |
| 132 | Molecular inversion probes reveal patterns of 9p21 deletion and copy number aberrations in childhood leukemia | 1.0 | 34 | Citations (PDF) |
| 133 | Pilot Study of Ethnic Variation in Biological Features of Childhood Acute Lymphoblastic Leukemia (ALL) in Utah.Blood, 2009, 114, 4117-4117 | 1.0 | 9 | Citations (PDF) |
| 134 | Identification of a novel p53 in-frame deletion in a Li–Fraumeni-like family | 1.5 | 9 | Citations (PDF) |
| 135 | Internet use among adolescent and young adults (AYA) with cancer | 1.5 | 45 | Citations (PDF) |
| 136 | Tissue Microarrays from Bone Marrow Aspirates for High-Throughput Assessment of Immunohistologic Markers in Pediatric Acute Leukemia | 1.3 | 4 | Citations (PDF) |
| 137 | Introduction of a Pediatric Palliative Care Curriculum for Pediatric Residents | 1.5 | 62 | Citations (PDF) |
| 138 | Delayed Platelet Engraftment and Early Increased Creatinine after Stem Cell Transplant Predicts Sustained Remission in Pediatric Leukemia.Blood, 2008, 112, 2159-2159 | 1.0 | 0 | Citations (PDF) |
| 139 | Molecular Inversion Probes (MIPs) Identify Novel Areas of Allelic Imbalance in Childhood Leukemia.Blood, 2007, 110, 1438-1438 | 1.0 | 0 | Citations (PDF) |
| 140 | Novel Allele Quantification Method To Classify Childhood Leukemia.Blood, 2006, 108, 2273-2273 | 1.0 | 0 | Citations (PDF) |
| 141 | Evolutionary Biology in the Medical School Curriculum | 5.2 | 33 | Citations (PDF) |
| 142 | Continuous Veno-Venous Hemofiltration May Improve Survival From Acute Respiratory Distress Syndrome After Bone Marrow Transplantation or Chemotherapy | 0.7 | 102 | Citations (PDF) |
| 143 | Jarisch-Herxheimer reaction associated with ciprofloxacin administration for tick-borne relapsing fever | 1.3 | 24 | Citations (PDF) |
