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174 peer-reviewed articles • 61,597 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Effects of Aging on Glucose and Lipid Metabolism in Mice
Aging Cell, 2025, 24,
6.812Citations (PDF)
2The bidirectional relationship between metabolism and cell cycle control
Trends in Cell Biology, 2024, 34, 136-149
12.051Citations (PDF)
3Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis13.755Citations (PDF)
4Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability
ELife, 2024, 13,
0.717Citations (PDF)
5A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
Nature Cell Biology, 2024, 26, 825-838
16.339Citations (PDF)
6Why do patients with cancer die?
Nature Reviews Cancer, 2024, 24, 578-589
60.7123Citations (PDF)
7Cancer tissue of origin constrains the growth and metabolism of metastases
Nature Metabolism, 2024, 6, 1668-1681
17.132Citations (PDF)
8Short-term post-fast refeeding enhances intestinal stemness via polyamines
Nature, 2024, 633, 895-904
37.955Citations (PDF)
9RAD21 promotes oncogenesis and lethal progression of prostate cancer7.58Citations (PDF)
10Slow TCA flux and ATP production in primary solid tumours but not metastases
Nature, 2023, 614, 349-357
37.9275Citations (PDF)
11Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
Science, 2023, 379, 996-1003
36.3152Citations (PDF)
12A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability6.739Citations (PDF)
13Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer13.761Citations (PDF)
14Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer4.51Citations (PDF)
15Manipulating mitochondrial electron flow enhances tumor immunogenicity
Science, 2023, 381, 1316-1323
36.3113Citations (PDF)
16Approaches to Study Tumor Metabolism in Mice6.60Citations (PDF)
17Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening13.723Citations (PDF)
18Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids
Cell Reports, 2023, 42, 113539
6.323Citations (PDF)
19Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors
Science Advances, 2022, 8,
10.931Citations (PDF)
20Ketogenic HMG‐CoA lyase and its product β‐hydroxybutyrate promote pancreatic cancer progression
EMBO Journal, 2022, 41,
7.369Citations (PDF)
21Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity13.731Citations (PDF)
22Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
Cancer Research, 2022, 82, 2403-2416
3.822Citations (PDF)
23Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited
Nature Metabolism, 2022, 4, 711-723
17.180Citations (PDF)
24The Impact of PIK3R1 Mutations and Insulin–PI3K–Glycolytic Pathway Regulation in Prostate Cancer
Clinical Cancer Research, 2022, 28, 3603-3617
6.851Citations (PDF)
25Nucleotide imbalance decouples cell growth from cell proliferation
Nature Cell Biology, 2022, 24, 1252-1264
16.3189Citations (PDF)
26Effect of exercise on tumor markers – Is exercise anti-tumorigenic in humans?: A scoping review of preliminary clinical investigations5.07Citations (PDF)
27Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression
Cancer Discovery, 2021, 11, 446-479
25.1202Citations (PDF)
28Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth
Cancer Immunology Research, 2021, 9, 415-429
4.222Citations (PDF)
29Increased demand for NAD+ relative to ATP drives aerobic glycolysis
Molecular Cell, 2021, 81, 691-707.e6
13.3534Citations (PDF)
30Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes1.19Citations (PDF)
31The metabolic landscape of RAS-driven cancers from biology to therapy
Nature Cancer, 2021, 2, 271-283
22.5245Citations (PDF)
32Fatty acid synthesis is required for breast cancer brain metastasis
Nature Cancer, 2021, 2, 414-428
22.5308Citations (PDF)
33Cell-programmed nutrient partitioning in the tumour microenvironment
Nature, 2021, 593, 282-288
37.9964Citations (PDF)
34Differential substrate use in EGF‐ and oncogenic KRAS‐stimulated human mammary epithelial cells
FEBS Journal, 2021, 288, 5629-5649
5.45Citations (PDF)
35Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells13.792Citations (PDF)
36Metabolomics in cancer research and emerging applications in clinical oncology251.5562Citations (PDF)
37The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
BMC Biology, 2021, 19,
3.91Citations (PDF)
38Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
Nature Metabolism, 2021, 3, 969-982
17.1118Citations (PDF)
39PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart
Circulation, 2021, 144, 712-727
18.066Citations (PDF)
40Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer1.14Citations (PDF)
41Low glycaemic diets alter lipid metabolism to influence tumour growth
Nature, 2021, 599, 302-307
37.9298Citations (PDF)
42Methionine synthase is essential for cancer cell proliferation in physiological folate environments
Nature Metabolism, 2021, 3, 1500-1511
17.182Citations (PDF)
43Cancer‐associated mutations in human pyruvate kinase M2 impair enzyme activity
FEBS Letters, 2020, 594, 646-664
2.726Citations (PDF)
44Metabolism in the Tumor Microenvironment5.478Citations (PDF)
45Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division13.737Citations (PDF)
46MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme13.744Citations (PDF)
47Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance
Cell Metabolism, 2020, 32, 391-403.e6
25.2130Citations (PDF)
48A metastasis map of human cancer cell lines
Nature, 2020, 588, 331-336
37.9415Citations (PDF)
49REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks7.545Citations (PDF)
50Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition
Cancer Discovery, 2020, 10, 1352-1373
25.1256Citations (PDF)
51Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1
Nature Cancer, 2020, 1, 589-602
22.570Citations (PDF)
52A Metabolomics Analysis of Adiposity and Advanced Prostate Cancer Risk in the Health Professionals Follow-Up Study
Metabolites, 2020, 10, 99
3.420Citations (PDF)
53Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer
Cancer Cell, 2020, 37, 147-156
33.0442Citations (PDF)
54Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation
Genes and Development, 2020, 34, 1253-1255
4.63Citations (PDF)
55Increased PHGDH expression promotes aberrant melanin accumulation
BMC Cancer, 2019, 19,
2.913Citations (PDF)
56Identification of DHODH as a therapeutic target in small cell lung cancer12.5137Citations (PDF)
57Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation
Nature Metabolism, 2019, 1, 861-867
17.1154Citations (PDF)
58Postdiagnosis Loss of Skeletal Muscle, but Not Adipose Tissue, Is Associated with Shorter Survival of Patients with Advanced Pancreatic Cancer1.151Citations (PDF)
59Determinants of nutrient limitation in cancer6.769Citations (PDF)
60Phenotypic selection with an intrabody library reveals an anti-apoptotic function of PKM2 requiring Mitofusin-1
PLoS Biology, 2019, 17, e2004413
5.016Citations (PDF)
61Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
Cell Metabolism, 2019, 29, 1410-1421.e4
25.2240Citations (PDF)
62Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance
Cancer Research, 2019, 79, 5723-5733
3.8127Citations (PDF)
63Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer13.770Citations (PDF)
64The redox requirements of proliferating mammalian cells
Journal of Biological Chemistry, 2018, 293, 7490-7498
2.2146Citations (PDF)
65Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 201813.36,013Citations (PDF)
66Height, Obesity, and the Risk of TMPRSS2:ERG-Defined Prostate Cancer1.119Citations (PDF)
67Lack of evidence for substrate channeling or flux between wildtype and mutant isocitrate dehydrogenase to produce the oncometabolite 2-hydroxyglutarate
Journal of Biological Chemistry, 2018, 293, 20051-20061
2.213Citations (PDF)
68Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth
EMBO Journal, 2018, 37,
7.3104Citations (PDF)
69Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
Cell, 2018, 175, 101-116.e25
33.6345Citations (PDF)
70Aspartate is an endogenous metabolic limitation for tumour growth
Nature Cell Biology, 2018, 20, 782-788
16.3341Citations (PDF)
71Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells
Cell Metabolism, 2018, 28, 573-587.e13
25.2186Citations (PDF)
72Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma4.827Citations (PDF)
73Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting
Cell Metabolism, 2018, 28, 706-720.e6
25.2190Citations (PDF)
74Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies2.0121Citations (PDF)
75Altered exocrine function can drive adipose wasting in early pancreatic cancer
Nature, 2018, 558, 600-604
37.9141Citations (PDF)
76JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition10.674Citations (PDF)
77Preparation of Lipid-Stripped Serum for the Study of Lipid Metabolism in Cell Culture
Bio-protocol, 2018, 8,
0.426Citations (PDF)
78Understanding the Intersections between Metabolism and Cancer Biology
Cell, 2017, 168, 657-669
33.62,046Citations (PDF)
79Biochemical Underpinnings of Immune Cell Metabolic Phenotypes
Immunity, 2017, 46, 703-713
22.6143Citations (PDF)
80Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation
Cancer Research, 2017, 77, 3217-3230
3.854Citations (PDF)
81Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
Nature Medicine, 2017, 23, 1362-1368
33.0630Citations (PDF)
82Targeting Metabolism for Cancer Therapy
Cell Chemical Biology, 2017, 24, 1161-1180
6.2865Citations (PDF)
83mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient
Cell, 2017, 171, 642-654.e12
33.6436Citations (PDF)
84Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions13.7400Citations (PDF)
85Nature and Nurture: What Determines Tumor Metabolic Phenotypes?
Cancer Research, 2017, 77, 3131-3134
3.870Citations (PDF)
86Critical Functions of the Lysosome in Cancer Biology11.8203Citations (PDF)
87PKM2 is not required for colon cancer initiated by APC loss4.836Citations (PDF)
88Metabolomic Biomarkers of Prostate Cancer: Prediction, Diagnosis, Progression, Prognosis, and Recurrence1.1121Citations (PDF)
89A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
Nature Chemical Biology, 2016, 12, 452-458
11.8525Citations (PDF)
90Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
Genes and Development, 2016, 30, 1020-1033
4.6154Citations (PDF)
91Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
Nature Reviews Cancer, 2016, 16, 680-693
60.7380Citations (PDF)
92Circadian Rhythm Disruption Promotes Lung Tumorigenesis
Cell Metabolism, 2016, 24, 324-331
25.2508Citations (PDF)
93The importance of serine metabolism in cancer
Journal of Cell Biology, 2016, 214, 249-257
5.4379Citations (PDF)
94Metabolic requirements for cancer cell proliferation4.8127Citations (PDF)
95Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin
Cell Metabolism, 2016, 24, 716-727
25.2334Citations (PDF)
96PKM 2, cancer metabolism, and the road ahead
EMBO Reports, 2016, 17, 1721-1730
5.2507Citations (PDF)
97Targeting MTHFD2 in acute myeloid leukemia
Journal of Experimental Medicine, 2016, 213, 1285-1306
9.3151Citations (PDF)
98Circulating Metabolites and Survival Among Patients With Pancreatic Cancer4.637Citations (PDF)
99Biophysical changes reduce energetic demand in growth factor–deprived lymphocytes
Journal of Cell Biology, 2016, 212, 439-447
5.433Citations (PDF)
100Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
Cell Metabolism, 2016, 23, 517-528
25.2720Citations (PDF)
101EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
Cell, 2016, 164, 884-895
33.6126Citations (PDF)
102Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
Developmental Cell, 2016, 36, 540-549
7.7609Citations (PDF)
103Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
Nature Medicine, 2016, 23, 235-241
33.0322Citations (PDF)
104The Role of Pyruvate Kinase M2 in Cancer Metabolism
Brain Pathology, 2015, 25, 781-783
5.047Citations (PDF)
105Lack of Evidence for PKM2 Protein Kinase Activity
Molecular Cell, 2015, 59, 850-857
13.398Citations (PDF)
106Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
Cancer Research, 2015, 75, 544-553
3.8848Citations (PDF)
107Famine versus feast: understanding the metabolism of tumors in vivo6.7179Citations (PDF)
108A roadmap for interpreting 13C metabolite labeling patterns from cells6.8624Citations (PDF)
109Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells
Cell, 2015, 162, 552-563
33.61,137Citations (PDF)
110An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation4.838Citations (PDF)
111Antibody-Mediated Neutralization of Perfringolysin O for Intracellular Protein Delivery
Molecular Pharmaceutics, 2015, 12, 1992-2000
4.216Citations (PDF)
112SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance
Nature, 2015, 520, 363-367
37.9363Citations (PDF)
113Dysregulated metabolism contributes to oncogenesis
Seminars in Cancer Biology, 2015, 35, S129-S150
13.7262Citations (PDF)
114Pyruvate kinase: Function, regulation and role in cancer5.3539Citations (PDF)
115Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
Molecular Cell, 2015, 57, 95-107
13.3253Citations (PDF)
116Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate
ACS Chemical Biology, 2015, 10, 510-516
3.7189Citations (PDF)
117A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect13.7112Citations (PDF)
118Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy
BMC Biology, 2014, 12,
3.9102Citations (PDF)
119Acetate metabolism in cancer cells4.841Citations (PDF)
120Targetable Signaling Pathway Mutations Are Associated with Malignant Phenotype in IDH -Mutant Gliomas
Clinical Cancer Research, 2014, 20, 2898-2909
6.8185Citations (PDF)
121Cell-State-Specific Metabolic Dependency in Hematopoiesis and Leukemogenesis
Cell, 2014, 158, 1309-1323
33.6343Citations (PDF)
122Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
Nature Medicine, 2014, 20, 1193-1198
33.0631Citations (PDF)
123A Fundamental Trade-off in Covalent Switching and Its Circumvention by Enzyme Bifunctionality in Glucose Homeostasis
Journal of Biological Chemistry, 2014, 289, 13010-13025
2.236Citations (PDF)
124Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
Molecular Cell, 2014, 55, 253-263
13.3548Citations (PDF)
125Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells13.7348Citations (PDF)
126Metabolic targets for cancer therapy79.7656Citations (PDF)
127PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells
Cell, 2013, 155, 397-409
33.6506Citations (PDF)
128Understanding Metabolic Regulation and Its Influence on Cell Physiology
Molecular Cell, 2013, 49, 388-398
13.3345Citations (PDF)
129Heterogeneity of tumor-induced gene expression changes in the human metabolic network
Nature Biotechnology, 2013, 31, 522-529
29.8428Citations (PDF)
130Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
Nature, 2013, 497, 633-637
37.91,632Citations (PDF)
131Exploiting tumor metabolism: challenges for clinical translation
Journal of Clinical Investigation, 2013, 123, 3648-3651
10.671Citations (PDF)
132Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons3.4108Citations (PDF)
133Detection of 2-Hydroxyglutarate in IDH -Mutated Glioma Patients by In Vivo Spectral-Editing and 2D Correlation Magnetic Resonance Spectroscopy12.5411Citations (PDF)
134Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy
Chemistry and Biology, 2012, 19, 1187-1198
4.7168Citations (PDF)
135Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Nature Chemical Biology, 2012, 8, 839-847
11.8755Citations (PDF)
136Targeting cancer metabolism: a therapeutic window opens79.71,329Citations (PDF)
137Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Nature Genetics, 2011, 43, 869-874
25.21,063Citations (PDF)
138Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation9.62,864Citations (PDF)
139Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
Nature, 2011, 481, 380-384
37.91,694Citations (PDF)
140Identification of small molecule inhibitors of pyruvate kinase M2
Biochemical Pharmacology, 2010, 79, 1118-1124
5.1228Citations (PDF)
141The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism7.5388Citations (PDF)
142Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply
Molecular Cell, 2010, 38, 487-499
13.3242Citations (PDF)
143Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Molecular Cell, 2010, 39, 171-183
13.31,888Citations (PDF)
144Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
Science, 2010, 329, 1492-1499
36.3619Citations (PDF)
145Metabolism strikes back: metabolic flux regulates cell signaling: Figure 1.
Genes and Development, 2010, 24, 2717-2722
4.6122Citations (PDF)
146Glucose Catabolism with Resultant Formation of Reactive Oxygen Species and Local Hypoxia Modulates the Induction and Expansion of Hematopoietic Stem Cells
Blood, 2010, 116, 408-408
4.80Citations (PDF)
147Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Nature, 2009, 462, 739-744
37.93,855Citations (PDF)
148Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Science, 2009, 324, 1029-1033
36.314,945Citations (PDF)
149Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth5.4713Citations (PDF)
150Pyruvate kinase M2 is a phosphotyrosine-binding protein
Nature, 2008, 452, 181-186
37.9946Citations (PDF)
151The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Nature, 2008, 452, 230-233
37.92,684Citations (PDF)
152Bcl-x Complements Saccharomyces cerevisiae Genes That Facilitate the Switch from Glycolytic to Oxidative Metabolism
Journal of Biological Chemistry, 2002, 277, 44870-44876
2.263Citations (PDF)
153Growth Factors Can Influence Cell Growth and Survival through Effects on Glucose Metabolism
Molecular and Cellular Biology, 2001, 21, 5899-5912
2.5494Citations (PDF)
154Bcl-x Promotes the Open Configuration of the Voltage-dependent Anion Channel and Metabolite Passage through the Outer Mitochondrial Membrane
Journal of Biological Chemistry, 2001, 276, 19414-19419
2.2347Citations (PDF)
155Redox regulation of p53 during hypoxia
Oncogene, 2000, 19, 3840-3848
6.5151Citations (PDF)
156Role of Oxidative Phosphorylation in Bax Toxicity
Molecular and Cellular Biology, 2000, 20, 3590-3596
2.5119Citations (PDF)
157Bcl-x L Prevents the Initial Decrease in Mitochondrial Membrane Potential and Subsequent Reactive Oxygen Species Production during Tumor Necrosis Factor Alpha-Induced Apoptosis
Molecular and Cellular Biology, 2000, 20, 5680-5689
2.5318Citations (PDF)
158Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival7.5415Citations (PDF)
159The CD28 and CTLA-4 Receptors Associate with the Serine/Threonine Phosphatase PP2A
Immunity, 2000, 13, 313-322
22.6288Citations (PDF)
160Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?
Nature Cell Biology, 1999, 1, E209-E216
16.3599Citations (PDF)
161Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms
EMBO Journal, 1999, 18, 632-643
7.3188Citations (PDF)
162Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria
Cell, 1997, 91, 627-637
33.61,369Citations (PDF)
163Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition
ELife, 0, 6,
0.7305Citations (PDF)
164Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer
ELife, 0, 6,
0.7225Citations (PDF)
165Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
ELife, 0, 8,
0.7575Citations (PDF)
166Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
ELife, 0, 9,
0.781Citations (PDF)
167Understanding the Warburg Effect in Cancer6.633Citations (PDF)
168Nutrient requirements of organ-specific metastasis in breast cancer
Nature, 0, 649, 1292-1301
37.912Citations (PDF)
169Abstract 7330: Hypoxia enhances sensitivity to RAS inhibition in PDAC
Cancer Research, 0, 86, 7330-7330
3.80Citations (PDF)
170Abstract 540: Cancer cells are sensitive to methionine cycle perturbation in low-lipid environments.
Cancer Research, 0, 86, 540-540
3.80Citations (PDF)
171Abstract 3366: Muscle iron overload contributes to cancer cachexia-induced muscle wasting
Cancer Research, 0, 86, 3366-3366
3.80Citations (PDF)
172Abstract 337: Off-target activation of GCN2 by BRAFV600inhibitors attenuates melanoma outgrowth.
Cancer Research, 0, 86, 337-337
3.80Citations (PDF)
173Aconitase 2 the rescue: A safeguard against excess mitochondrial citrate
Molecular Cell, 0, 86, 1595-1597
13.30Citations (PDF)
174The Influence of Diet on Cancer Progression and Treatment10.90Citations (PDF)