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234 peer-reviewed articles • 26,789 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1One Shock, Not One Cure: Electroporation Reveals Disease-Specific Constraints in Hepatocyte Gene Editing Therapy
Biology, 2025, 14, 1091
2.21Citations (PDF)
2Complete correction of murine phenylketonuria by selection-enhanced hepatocyte transplantation
Hepatology, 2024, 79, 1088-1097
9.612Citations (PDF)
3Long‐term combination therapy with metformin and oxymetholone in a Fanconi anemia mouse model
Pediatric Blood and Cancer, 2024, 71,
0.92Citations (PDF)
4In vivo selection of hepatocytes
Hepatology, 2024, ,
9.65Citations (PDF)
5Rapid in vivo multiplexed editing (RIME) of the adult mouse liver
Hepatology, 2023, 78, 486-502
9.610Citations (PDF)
6A DNA methylation atlas of normal human cell types
Nature, 2023, 613, 355-364
30.6631Citations (PDF)
7Replication stress increases mitochondrial metabolism and mitophagy in FANCD2 deficient fetal liver hematopoietic stem cells
Frontiers in Oncology, 2023, 13,
1.76Citations (PDF)
8Strong ubiquitous micro-promoters for recombinant adeno-associated viral vectors
Molecular Therapy - Methods and Clinical Development, 2023, 29, 504-512
3.027Citations (PDF)
9In vivo tracing of the Cytokeratin 14 lineages using self-cleaving guide RNAs and CRISPR/Cas9
Developmental Biology, 2023, 504, 120-127
1.30Citations (PDF)
10Development of a Beta Cell-Specific Expression Control Element for Recombinant Adeno-Associated Virus
Human Gene Therapy, 2022, 33, 789-800
2.33Citations (PDF)
11Self-cleaving guide RNAs enable pharmacological selection of precise gene editing events in vivo
Nature Communications, 2022, 13,
10.813Citations (PDF)
12Induced Liver Regeneration Enhances CRISPR/Cas9-Mediated Gene Repair in Tyrosinemia Type 1
Human Gene Therapy, 2021, 32, 294-301
2.318Citations (PDF)
13MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia
Cell Stem Cell, 2021, 28, 33-47.e8
11.652Citations (PDF)
14Inhibition of TGFβ1 and TGFβ3 promotes hematopoiesis in Fanconi anemia
Experimental Hematology, 2021, 93, 70-84.e4
0.621Citations (PDF)
15Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice
Molecular Therapy, 2021, 29, 680-690
6.099Citations (PDF)
16Proliferative polyploid cells give rise to tumors via ploidy reduction
Nature Communications, 2021, 12,
10.892Citations (PDF)
17Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes
Science Translational Medicine, 2021, 13,
8.732Citations (PDF)
18Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Hepatology, 2021, 74, 444-457
9.644Citations (PDF)
19Liver-humanized mice fed a NASH-diet are an advanced model to study cardiometabolic diseases
Atherosclerosis, 2021, 331, e143
1.90Citations (PDF)
20AAV integration in human hepatocytes
Molecular Therapy, 2021, 29, 2898-2909
6.0125Citations (PDF)
21In vitro expansion of cirrhosis derived liver epithelial cells with defined small molecules
Stem Cell Research, 2021, 56, 102523
0.38Citations (PDF)
22The Significance of Polyploid Hepatocytes During Aging Process
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11, 1347-1349
4.022Citations (PDF)
23Generation of functional ciliated cholangiocytes from human pluripotent stem cells
Nature Communications, 2021, 12,
10.840Citations (PDF)
24AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria
Molecular Therapy - Methods and Clinical Development, 2020, 17, 234-245
3.091Citations (PDF)
25In Vivo Lineage Tracing of Polyploid Hepatocytes Reveals Extensive Proliferation during Liver Regeneration
Cell Stem Cell, 2020, 26, 34-47.e3
11.6178Citations (PDF)
26Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans
Hepatology, 2020, 72, 656-670
9.639Citations (PDF)
27Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes
JHEP Reports, 2020, 2, 100065
3.125Citations (PDF)
28Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure
Gastroenterology, 2019, 157, 552-568
0.9127Citations (PDF)
29Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
Nature, 2019, 567, 43-48
30.6242Citations (PDF)
30Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction
American Journal of Human Genetics, 2019, 105, 1237-1253
4.059Citations (PDF)
31Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model
Pediatric Blood and Cancer, 2019, 66,
0.98Citations (PDF)
32Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors
JCI Insight, 2019, 4,
3.795Citations (PDF)
33Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
Molecular Therapy, 2018, 26, 1327-1342
6.030Citations (PDF)
34Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity
Molecular Therapy, 2018, 26, 289-303
6.0164Citations (PDF)
35Monitoring liver damage using hepatocyte-specific methylation markers in cell-free circulating DNA
JCI Insight, 2018, 3,
3.7132Citations (PDF)
36Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
Cell, 2018, 175, 1607-1619.e15
23.4322Citations (PDF)
37Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease
Nature Communications, 2018, 9,
10.8976Citations (PDF)
38A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia
Cell Stem Cell, 2017, 20, 478-489.e5
11.6106Citations (PDF)
39Diagnosis and treatment of tyrosinemia type I: a US and Canadian consensus group review and recommendations
Genetics in Medicine, 2017, 19, 1380-1395
3.3224Citations (PDF)
40Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
Nature Communications, 2017, 8,
10.8145Citations (PDF)
41Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability
Nature Communications, 2017, 8,
10.870Citations (PDF)
42Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes
Stem Cell Reports, 2017, 9, 478-489
3.079Citations (PDF)
43Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1
American Journal of Pathology, 2017, 187, 33-41
2.820Citations (PDF)
44Reprogramming human gallbladder cells into insulin-producing β-like cells
PLoS ONE, 2017, 12, e0181812
1.539Citations (PDF)
45Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice
Blood, 2016, 128, 2774-2784
3.673Citations (PDF)
46Efficient generation of pancreatic β-like cells from the mouse gallbladder
Stem Cell Research, 2016, 17, 587-596
0.314Citations (PDF)
47Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function
Cell Metabolism, 2016, 23, 909-920
20.8244Citations (PDF)
48Single-Cell Mass Cytometry Analysis of the Human Endocrine Pancreas
Cell Metabolism, 2016, 24, 616-626
20.8165Citations (PDF)
49Stem Cells and Regeneration in the Digestive System: Keystone Meeting
Gastroenterology, 2016, 151, e6-e9
0.90Citations (PDF)
50Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma
Human Mutation, 2016, 37, 1097-1105
1.032Citations (PDF)
51Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1
Science Translational Medicine, 2016, 8,
8.769Citations (PDF)
52A universal system to select gene-modified hepatocytes in vivo
Science Translational Medicine, 2016, 8,
8.743Citations (PDF)
53Human islets contain four distinct subtypes of β cells
Nature Communications, 2016, 7,
10.8377Citations (PDF)
54TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia
Cell Stem Cell, 2016, 18, 668-681
11.6152Citations (PDF)
55Stem cells versus plasticity in liver and pancreas regeneration
Nature Cell Biology, 2016, 18, 238-245
12.6168Citations (PDF)
56Identification of tissue-specific cell death using methylation patterns of circulating DNA
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113,
5.2590Citations (PDF)
57The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice
Stem Cell Research, 2015, 15, 130-140
0.327Citations (PDF)
58Fibroblast Growth Factor Signaling Controls Liver Size in Mice With Humanized Livers
Gastroenterology, 2015, 149, 728-740.e15
0.9109Citations (PDF)
59Oxymetholone Therapy of Fanconi Anemia Suppresses Osteopontin Transcription and Induces Hematopoietic Stem Cell Cycling
Stem Cell Reports, 2015, 4, 90-102
3.032Citations (PDF)
60Directed differentiation of cholangiocytes from human pluripotent stem cells
Nature Biotechnology, 2015, 33, 853-861
19.7311Citations (PDF)
61Novel surface markers directed against adult human gallbladder
Stem Cell Research, 2015, 15, 172-181
0.37Citations (PDF)
62Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Nature Biotechnology, 2014, 32, 551-553
19.7891Citations (PDF)
63Pharmacologic inhibition of L‐tyrosine degradation ameliorates cerebral dopamine deficiency in murine phenylketonuria (PKU)
Journal of Inherited Metabolic Disease, 2014, 37, 735-743
2.647Citations (PDF)
64Extensive double humanization of both liver and hematopoiesis in FRGN mice
Stem Cell Research, 2014, 13, 404-412
0.3136Citations (PDF)
65Bipotential Adult Liver Progenitors Are Derived from Chronically Injured Mature Hepatocytes
Cell Stem Cell, 2014, 15, 605-618
11.6510Citations (PDF)
66The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar
Stem Cell Research, 2014, 13, 275-283
0.376Citations (PDF)
67Clonal Tracing of Sox9+ Liver Progenitors in Mouse Oval Cell Injury
Hepatology, 2014, 60, 278-289
9.6214Citations (PDF)
68Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease
Stem Cell Research, 2014, 13, 144-153
0.364Citations (PDF)
69Human pancreatic cancer fusion 2 (HPC2) 1‐B3: A novel monoclonal antibody to screen for pancreatic ductal dysplasia
Cancer Cytopathology, 2013, 121, 37-46
1.33Citations (PDF)
70Response to “Can ‘humanized’ mice improve drug development in the 21st century?”
Trends in Pharmacological Sciences, 2013, 34, 425
8.25Citations (PDF)
71Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming
Stem Cell Research, 2013, 11, 503-515
0.346Citations (PDF)
72Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis
Immunity, 2013, 39, 874-884
16.6145Citations (PDF)
73New potential cell source for hepatocyte transplantation: Discarded livers from metabolic disease liver transplants
Stem Cell Research, 2013, 11, 563-573
0.358Citations (PDF)
74Mice With Human Livers
Gastroenterology, 2013, 145, 1209-1214
0.9136Citations (PDF)
75Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice
Stem Cell Research, 2013, 11, 687-692
0.312Citations (PDF)
76p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver
Hepatology, 2013, 57, 2004-2013
9.693Citations (PDF)
77In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
Nature, 2013, 494, 247-250
30.61,529Citations (PDF)
78Epigenomic plasticity enables human pancreatic α to β cell reprogramming
Journal of Clinical Investigation, 2013, 123, 1275-1284
6.6399Citations (PDF)
79Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
PLoS ONE, 2013, 8, e78550
1.550Citations (PDF)
80Selection and evaluation of clinically relevant AAV variants in a xenograft liver model
Nature, 2013, 506, 382-386
30.6443Citations (PDF)
81AAV Vectors Containing rDNA Homology Display Increased Chromosomal Integration and Transgene Persistence
Molecular Therapy, 2012, 20, 1902-1911
6.045Citations (PDF)
82In Vivo Selection of Transplanted Hepatocytes by Pharmacological Inhibition of Fumarylacetoacetate Hydrolase in Wild-type Mice
Molecular Therapy, 2012, 20, 1981-1987
6.017Citations (PDF)
83Ribosomal DNA Integrating rAAV-rDNA Vectors Allow for Stable Transgene Expression
Molecular Therapy, 2012, 20, 1912-1923
6.034Citations (PDF)
84Frequent Aneuploidy Among Normal Human Hepatocytes
Gastroenterology, 2012, 142, 25-28
0.9197Citations (PDF)
85AAV-Mediated Gene Targeting Is Significantly Enhanced by Transient Inhibition of Nonhomologous End Joining or the Proteasome In Vivo
Human Gene Therapy, 2012, 23, 658-665
2.335Citations (PDF)
86Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells
Cell Stem Cell, 2012, 11, 36-49
11.6310Citations (PDF)
87The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma
Human Pathology, 2012, 43, 1583-1589
1.722Citations (PDF)
88Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
Journal of Clinical Investigation, 2012, 122, 3618-3628
6.6241Citations (PDF)
89Aneuploidy as a mechanism for stress-induced liver adaptation
Journal of Clinical Investigation, 2012, 122, 3307-3315
6.6161Citations (PDF)
90Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers
Molecular and Cellular Endocrinology, 2011, 339, 144-150
2.050Citations (PDF)
91Transcriptomes of the major human pancreatic cell types
Diabetologia, 2011, 54,
4.9208Citations (PDF)
92Efficient production of Fah -null heterozygote pigs by chimeric adeno-associated virus-mediated gene knockout and somatic cell nuclear transfer
Hepatology, 2011, 54, 1351-1359
9.679Citations (PDF)
93Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
Journal of Experimental Medicine, 2011, 208, 1963-1976
5.9210Citations (PDF)
94Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential
Genes and Development, 2011, 25, 1185-1192
2.8145Citations (PDF)
95Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
Genes and Development, 2011, 25, 1193-1203
2.8223Citations (PDF)
96Fancd2 −/− mice have hematopoietic defects that can be partially corrected by resveratrol
Blood, 2010, 116, 5140-5148
3.696Citations (PDF)
97106 IDENTIFICATION OF JOINT OCHRONOSIS IN A MOUSE MODEL OF ALKAPTONURIA
Osteoarthritis and Cartilage, 2010, 18, S54
3.00Citations (PDF)
98Adeno‐associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo†‡
Hepatology, 2010, 51, 1200-1208
9.6130Citations (PDF)
99The ploidy conveyor of mature hepatocytes as a source of genetic variation
Nature, 2010, 467, 707-710
30.6497Citations (PDF)
100Non-Invasive Stem Cell Therapy in a Rat Model for Retinal Degeneration and Vascular Pathology
PLoS ONE, 2010, 5, e9200
1.5134Citations (PDF)
101Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer
Cancer Research, 2010, 70, 9959-9968
2.689Citations (PDF)
102Therapeutic Liver Reconstitution With Murine Cells Isolated Long After Death
Gastroenterology, 2010, 139, 1019-1029
0.931Citations (PDF)
103Chromosomal Integration of Adenoviral Vector DNA In Vivo
Journal of Virology, 2010, 84, 9987-9994
2.489Citations (PDF)
104Validation of Fanconi anemia complementation Group A assignment using molecular analysis
Genetics in Medicine, 2009, 11, 183-192
3.318Citations (PDF)
105Ploidy Reductions in Murine Fusion-Derived Hepatocytes
PLoS Genetics, 2009, 5, e1000385
2.2100Citations (PDF)
106Embryonic Lethality after Combined Inactivation of Fancd2 and Mlh1 in Mice
Cancer Research, 2009, 69, 9431-9438
2.69Citations (PDF)
107Generation of Monoclonal Antibodies Specific for Cell Surface Molecules Expressed on Early Mouse Endoderm
Stem Cells, 2009, 27, 2103-2113
2.739Citations (PDF)
108CDX2 in the formation of the trophectoderm lineage in primate embryos
Developmental Biology, 2009, 335, 179-187
1.338Citations (PDF)
109Stem Cells and Liver Regeneration
Gastroenterology, 2009, 137, 466-481
0.9529Citations (PDF)
110Activation of nuclear factor E2‐related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development†
Hepatology, 2008, 48, 487-496
9.638Citations (PDF)
111Surface markers for the murine oval cell response†
Hepatology, 2008, 48, 1282-1291
9.688Citations (PDF)
112CXCR4 induction in hematopoietic progenitor cells from Fanca−/−, -c−/−, and -d2−/− mice
Experimental Hematology, 2008, 36, 273-282
0.613Citations (PDF)
113Loss of p21 Permits Carcinogenesis from Chronically Damaged Liver and Kidney Epithelial Cells despite Unchecked Apoptosis
Cancer Cell, 2008, 14, 59-67
28.462Citations (PDF)
114Signaling networks in hepatic oval cell activation
Stem Cell Research, 2008, 1, 90-102
0.353Citations (PDF)
115Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers
Stem Cell Research, 2008, 1, 183-194
0.3116Citations (PDF)
116ERCC1 is required for FANCD2 focus formation
Molecular Genetics and Metabolism, 2008, 95, 66-73
0.518Citations (PDF)
117W1838 Development of Monoclonal Antibodies to Aid in the Diagnosis of Pancreatic Cancer
Gastroenterology, 2008, 134, A-912
0.90Citations (PDF)
118Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics
Biochemical Journal, 2007, 402, 251-260
2.317Citations (PDF)
119Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein, FANCD2, Sustain a Significant Group of FA-D2 Patients with Severe Phenotype
American Journal of Human Genetics, 2007, 80, 895-910
4.0132Citations (PDF)
120Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice
Nature Biotechnology, 2007, 25, 903-910
19.7819Citations (PDF)
121Bone marrow-derived cells fuse with normal and transformed intestinal stem cells
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103, 6321-6325
5.2266Citations (PDF)
122Sustained Phosphorylation of Bid Is a Marker for Resistance to Fas-Induced Apoptosis During Chronic Liver Diseases
Gastroenterology, 2006, 130, 104-119
0.933Citations (PDF)
123Natural gene therapy in monozygotic twins with Fanconi anemia
Blood, 2006, 107, 3084-3090
3.681Citations (PDF)
124Principles of therapeutic liver repopulation
Journal of Inherited Metabolic Disease, 2006, 29, 421-425
2.653Citations (PDF)
125Seeking Consensus: A Clarification and Defense of Altered Nuclear Transfer
Hastings Center Report, 2006, 36, 42-50
0.613Citations (PDF)
126Myeloid lineage progenitors give rise to vascular endothelium
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103, 13156-13161
5.2189Citations (PDF)
127In Vivo Genetic Selection of Renal Proximal Tubules
Molecular Therapy, 2006, 13, 49-58
6.060Citations (PDF)
128Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice
Journal of Clinical Investigation, 2006, 116, 3070-3082
6.6219Citations (PDF)
129Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin
Blood, 2005, 105, 1003-1009
3.6122Citations (PDF)
130Liver Repair by Intra- and Extrahepatic Progenitors
Stem Cell Reviews and Reports, 2005, 1, 061-064
5.633Citations (PDF)
131Large-Scale Molecular Characterization of Adeno-Associated Virus Vector Integration in Mouse Liver
Journal of Virology, 2005, 79, 3606-3614
2.4172Citations (PDF)
132In Vivo Correction of Murine Hereditary Tyrosinemia Type I by ϕC31 Integrase-Mediated Gene Delivery
Molecular Therapy, 2005, 11, 399-408
6.0131Citations (PDF)
133Low Therapeutic Threshold for Hepatocyte Replacement in Murine Phenylketonuria
Molecular Therapy, 2005, 12, 337-344
6.063Citations (PDF)
134Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining
Human Molecular Genetics, 2005, 14, 3027-3033
2.157Citations (PDF)
135The Origin of Hepatocytes
Gastroenterology, 2005, 128, 2158-2160
0.922Citations (PDF)
136Repair Kinetics of Genomic Interstrand DNA Cross-Links: Evidence for DNA Double-Strand Break-Dependent Activation of the Fanconi Anemia/BRCA Pathway
Molecular and Cellular Biology, 2004, 24, 123-134
1.5221Citations (PDF)
137Liver-Directed Adenoviral Gene Transfer in Murine Succinate Semialdehyde Dehydrogenase Deficiency
Molecular Therapy, 2004, 9, 527-539
6.028Citations (PDF)
138Renal proximal tubular cells acquire resistance to cell death stimuli in mice with hereditary tyrosinemia type 1
Kidney International, 2004, 66, 990-1000
4.27Citations (PDF)
139Myelomonocytic cells are sufficient for therapeutic cell fusion in liver
Nature Medicine, 2004, 10, 744-748
22.6421Citations (PDF)
140Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death
Hepatology, 2004, 39, 433-443
9.663Citations (PDF)
141Interstrand crosslink-induced radials form between non-homologous chromosomes, but are absent in sex chromosomes
DNA Repair, 2004, 3, 535-542
1.832Citations (PDF)
142Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents
Biochemical Pharmacology, 2003, 66, 2029-2038
3.731Citations (PDF)
143Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency
Human Mutation, 2003, 22, 442-450
1.0137Citations (PDF)
144Murine succinate semialdehyde dehydrogenase deficiency
Annals of Neurology, 2003, 54, S81-S90
4.649Citations (PDF)
145Cell fusion is the principal source of bone-marrow-derived hepatocytes
Nature, 2003, 422, 897-901
30.61,567Citations (PDF)
146AAV serotype 2 vectors preferentially integrate into active genes in mice
Nature Genetics, 2003, 34, 297-302
14.1385Citations (PDF)
147The Fanconi anaemia/BRCA pathway
Nature Reviews Cancer, 2003, 3, 23-34
34.5796Citations (PDF)
148Pancreatic–hepatic switches in vivo
Mechanisms of Development, 2003, 120, 99-106
2.651Citations (PDF)
149The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases
Cell, 2003, 113, 445-456
23.4341Citations (PDF)
150Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice
Genes and Development, 2003, 17, 2021-2035
2.8254Citations (PDF)
151The origin and liver repopulating capacity of murine oval cells
Proceedings of the National Academy of Sciences of the United States of America, 2003, 100, 11881-11888
5.2405Citations (PDF)
152Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice
Molecular Therapy, 2003, 7, 101-111
6.048Citations (PDF)
153The Role of Bone Marrow Stem Cells in Liver Regeneration
Seminars in Liver Disease, 2003, 23, 363-372
2.094Citations (PDF)
154Reply to “Involvement of oxidative stress in Fanconi's anaemia: from phenotype to FA protein functions”
Nature Reviews Cancer, 2003, 3, 78-78
34.50Citations (PDF)
155In Vivo Correction of Murine Tyrosinemia Type I by DNA-Mediated Transposition
Molecular Therapy, 2002, 6, 759-769
6.0141Citations (PDF)
156Attenuation of the formation of DNA-repair foci containing RAD51 in Fanconi anaemia
Carcinogenesis, 2002, 23, 1121-1126
2.284Citations (PDF)
157BRCA1 interacts directly with the Fanconi anemia protein FANCA
Human Molecular Genetics, 2002, 11, 2591-2597
2.1104Citations (PDF)
158Therapeutic Intervention in Mice Deficient for Succinate Semialdehyde Dehydrogenase (γ-Hydroxybutyric Aciduria)
Journal of Pharmacology and Experimental Therapeutics, 2002, 302, 180-187
2.384Citations (PDF)
159Maleylacetoacetate Isomerase ( MAAI/GSTZ )-Deficient Mice Reveal a Glutathione-Dependent Nonenzymatic Bypass in Tyrosine Catabolism
Molecular and Cellular Biology, 2002, 22, 4943-4951
1.593Citations (PDF)
160S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51
Blood, 2002, 100, 2414-2420
3.6440Citations (PDF)
161Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors
Blood, 2002, 100, 2732-2736
3.682Citations (PDF)
162Kinetics of Liver Repopulation after Bone Marrow Transplantation
American Journal of Pathology, 2002, 161, 565-574
2.8235Citations (PDF)
163Long-Term Therapy with NTBC and Tyrosine-Restricted Diet in a Murine Model of Hereditary Tyrosinemia Type I
Molecular Genetics and Metabolism, 2002, 75, 38-45
0.584Citations (PDF)
164Mutations in PHF6 are associated with Börjeson–Forssman –Lehmann syndrome
Nature Genetics, 2002, 32, 661-665
14.1210Citations (PDF)
165Sandgren EP, Palmiter RD, Heckel JL, Daugherty CC, Brinster RL, Degen JL. Complete hepatic regeneration after somatic deletion of an albumin–plasminogen activator transgene [Cell 1991;66:245–256]
Journal of Hepatology, 2002, 37, 422-424
6.79Citations (PDF)
166Fanconi anemia group A and C double-mutant mice
Experimental Hematology, 2002, 30, 679-688
0.663Citations (PDF)
167In vivo administration of interferon γ does not cause marrow aplasia in mice with a targeted disruption of FANCC
Experimental Hematology, 2002, 30, 1257-1262
0.67Citations (PDF)
168SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11
Oncogene, 2002, 21, 4873-4878
5.257Citations (PDF)
169Transition of Stem Cells to Therapeutically Functional Tissue‐Specific Cells
Annals of the New York Academy of Sciences, 2002, 961, 305-306
2.66Citations (PDF)
170The 4N Cell Cycle Delay in Fanconi Anemia Reflects Growth Arrest in Late S Phase
Molecular Genetics and Metabolism, 2001, 74, 403-412
0.570Citations (PDF)
171Liver Repopulation and Correction of Metabolic Liver Disease by Transplanted Adult Mouse Pancreatic Cells
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194The Repopulation Potential of Hepatocyte Populations Differing in Size and Prior Mitotic Expansion
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195Gene Structure, Chromosomal Location, and Expression Pattern of Maleylacetoacetate Isomerase
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198Subtyping Analysis of Fanconi Anemia by Immunoblotting and Retroviral Gene Transfer
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199DNA Cross-Linker–Induced G2/M Arrest in Group C Fanconi Anemia Lymphoblasts Reflects Normal Checkpoint Function
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200Adenovirus-Mediated Gene Therapy in a Mouse Model of Hereditary Tyrosinemia Type I
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201Molecular Biology of Fanconi Anemia: Implications for Diagnosis and Therapy
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202Inactivation of the Fanconi Anemia Group C Gene Augments Interferon-γ–Induced Apoptotic Responses in Hematopoietic Cells
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207Rapid nonradioactive assay for the detection of the common French Canadian tyrosinemia type I mutation
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209Microcell mediated chromosome transfer maps the Fanconi anaemia group D gene to chromosome 3p
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