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398 PR articles • 68,974 PR citations • Sorted by year • Download PDF (PDF by citations)
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1α-Synuclein pathology as a target in neurodegenerative diseases
Nature Reviews Neurology, 2025, 21, 32-47
28.648Citations (PDF)
2Elucidating metabolite and pH variations in stroke through guanidino, amine and amide CEST MRI: A comparative multi-field study at 9.4T and 3T
NeuroImage, 2025, 305, 120993
4.42Citations (PDF)
3Proteome-wide microarray-based screening of PAR-binding proteins15.58Citations (PDF)
4Cerebellum mitochondrial DNA copy number is increased in Parkinson’s disease3.60Citations (PDF)
5Interspecies chimerism with human embryonic stem cells generates functional human dopamine neurons at low efficiency
Stem Cell Reports, 2024, 19, 54-67
4.45Citations (PDF)
6Protein Translation in the Pathogenesis of Parkinson’s Disease4.47Citations (PDF)
7Blocking the <scp>Self‐Destruct</scp> Program of Dopamine Neurons through <scp>Macrophage Migration Inhibitory Factor</scp> Nuclease Inhibition
Movement Disorders, 2024, 39, 644-650
4.62Citations (PDF)
8Poly(<scp>ADP</scp>‐ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation
FASEB Journal, 2024, 38,
0.610Citations (PDF)
9Parthanatos: Mechanisms, modulation, and therapeutic prospects in neurodegenerative disease and stroke
Biochemical Pharmacology, 2024, 228, 116174
5.139Citations (PDF)
10Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein13.732Citations (PDF)
11Mature microRNA-binding protein QKI suppresses extracellular microRNA let-7b release2.45Citations (PDF)
12Poly ADP-ribose signaling is dysregulated in Huntington disease7.511Citations (PDF)
13CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration
Science Advances, 2024, 10,
10.91Citations (PDF)
14The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson’s disease12.526Citations (PDF)
15Apoptotic cell death in disease—Current understanding of the NCCD 2023
Cell Death and Differentiation, 2023, 30, 1097-1154
13.3300Citations (PDF)
16Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate12.517Citations (PDF)
17<scp>PARIS</scp> undergoes liquid–liquid phase separation and poly(<scp>ADP</scp>‐ribose)‐mediated solidification
EMBO Reports, 2023, 24,
5.28Citations (PDF)
18Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease12.549Citations (PDF)
19CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders
Biological Psychiatry, 2022, 92, 815-826
5.417Citations (PDF)
20Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups
Brain, 2022, 145, 1757-1762
8.451Citations (PDF)
21Waiting for PARIS—A Biological Target in Search of a Drug3.33Citations (PDF)
22Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver
IScience, 2022, 25, 103996
3.637Citations (PDF)
23Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson’s disease
Science Advances, 2022, 8,
10.923Citations (PDF)
24STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy7.5174Citations (PDF)
25A high-affinity cocaine binding site associated with the brain acid soluble protein 17.57Citations (PDF)
26Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease
Movement Disorders, 2022, 37, 1454-1464
4.627Citations (PDF)
27PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease
Cell, 2022, 185, 1943-1959.e21
33.797Citations (PDF)
28Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease
Neuron, 2022, 110, 2422-2437.e9
11.0171Citations (PDF)
29AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 113.77Citations (PDF)
30Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin7.5105Citations (PDF)
31Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteins12.521Citations (PDF)
32The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA<sup>D257A/D257A</sup>Mitochondrial Mutator Mice
Journal of Neuroscience, 2022, 42, 9263-9277
3.719Citations (PDF)
33APDM gait and balance measures fail to predict symptom progression rate in Parkinson's disease2.43Citations (PDF)
34Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson’s Disease
CNS Drugs, 2022, 36, 1249-1267
6.37Citations (PDF)
35Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways5.524Citations (PDF)
36Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease
Nano Today, 2021, 36, 101027
9.9128Citations (PDF)
37Brainstem Pathologies Correlate With Depression and Psychosis in Parkinson's Disease1.724Citations (PDF)
38Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Nature Genetics, 2021, 53, 294-303
25.2368Citations (PDF)
39Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice3.446Citations (PDF)
40Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease
JAMA Neurology, 2021, 78, 312
17.6123Citations (PDF)
41The cell biology of Parkinson’s disease5.4135Citations (PDF)
42AIF3 splicing switch triggers neurodegeneration14.18Citations (PDF)
43Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease5.0160Citations (PDF)
44Semantic fluency and processing speed are reduced in non-cognitively impaired participants with Parkinson’s disease1.015Citations (PDF)
45Targeting Parthanatos in Ischemic Stroke2.451Citations (PDF)
46Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons
STAR Protocols, 2021, 2, 100405
1.111Citations (PDF)
47Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease7.5101Citations (PDF)
48Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson’s Disease
Journal of Proteome Research, 2021, 20, 3428-3443
3.452Citations (PDF)
49Neurodegenerative disorders and gut-brain interactions10.695Citations (PDF)
50Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis
Neurotherapeutics, 2021, 18, 1834-1848
6.133Citations (PDF)
51PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease12.558Citations (PDF)
52Seeking progress in disease modification in Parkinson disease2.613Citations (PDF)
53Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration
Brain, 2021, 144, 3674-3691
8.424Citations (PDF)
54LRRK2 Modulates the Exocyst Complex Assembly by Interacting with Sec8
Cells, 2021, 10, 203
4.71Citations (PDF)
55USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
Nucleic Acids Research, 2021, 49, 11083-11102
15.525Citations (PDF)
56Parkinson Disease: Translating Insights from Molecular Mechanisms to Neuroprotection
Pharmacological Reviews, 2021, 73, 1204-1268
15.729Citations (PDF)
57TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
Neuron, 2021, 109, 3758-3774.e11
11.046Citations (PDF)
58Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation
Scientific Reports, 2021, 11,
3.414Citations (PDF)
59Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains
ENeuro, 2021, 8, ENEURO.0310-21.2021
2.112Citations (PDF)
60Recent advances in preventing neurodegenerative diseases
Faculty Reviews, 2021, 10,
4.115Citations (PDF)
61Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia
Brain, 2020, 143, 234-248
8.4225Citations (PDF)
62Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis
Cell Stem Cell, 2020, 27, 633-645.e7
16.454Citations (PDF)
63Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
Cell Reports, 2020, 32, 107908
6.3266Citations (PDF)
64Determinants of seeding and spreading of α-synuclein pathology in the brain
Science Advances, 2020, 6,
10.9101Citations (PDF)
65Microglia and astrocyte dysfunction in parkinson's disease
Neurobiology of Disease, 2020, 144, 105028
5.1331Citations (PDF)
66Molecular Mediation of Prion-like α-Synuclein Fibrillation from Toxic PFFs to Nontoxic Species
ACS Applied Bio Materials, 2020, 3, 6096-6102
4.714Citations (PDF)
67Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons
Stem Cell Reports, 2020, 15, 629-645
4.471Citations (PDF)
68AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF
Cell Reports, 2020, 33, 108329
6.318Citations (PDF)
69Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid2.812Citations (PDF)
70PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency14.181Citations (PDF)
71PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease14.1432Citations (PDF)
72Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke
PLoS ONE, 2020, 15, e0231978
2.313Citations (PDF)
73NLRP3 inflammasome activation in dopamine neurons contributes to neurodegeneration in Parkinson’s Disease
FASEB Journal, 2020, 34, 1-1
0.67Citations (PDF)
74Integration of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons into Rat Brain
Bio-protocol, 2020, 10,
0.42Citations (PDF)
75Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis5.058Citations (PDF)
76Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease
Neuron, 2019, 103, 627-641.e7
11.01,215Citations (PDF)
77Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease
Brain, 2019, 142, 2380-2401
8.466Citations (PDF)
78The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration
Movement Disorders, 2019, 34, 959-969
4.688Citations (PDF)
79Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
Journal of Experimental Medicine, 2019, 216, 1411-1430
9.2236Citations (PDF)
80Heritability and genetic variance of dementia with Lewy bodies
Neurobiology of Disease, 2019, 127, 492-501
5.138Citations (PDF)
81Assessment of APOE in atypical parkinsonism syndromes
Neurobiology of Disease, 2019, 127, 142-146
5.126Citations (PDF)
82Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic Activities
ENeuro, 2019, 6, ENEURO.0148-19.2019
2.119Citations (PDF)
83Promising disease-modifying therapies for Parkinson’s disease12.559Citations (PDF)
84Genetic analysis of neurodegenerative diseases in a pathology cohort
Neurobiology of Aging, 2019, 76, 214.e1-214.e9
3.444Citations (PDF)
85Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons4.148Citations (PDF)
86A comprehensive screening of copy number variability in dementia with Lewy bodies
Neurobiology of Aging, 2019, 75, 223.e1-223.e10
3.414Citations (PDF)
87The AAA + ATPase Thorase is neuroprotective against ischemic injury4.715Citations (PDF)
88Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease2.6137Citations (PDF)
89DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders5.241Citations (PDF)
90A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy
Brain, 2018, 141, 651-661
8.459Citations (PDF)
91Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice7.596Citations (PDF)
92Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 201813.35,678Citations (PDF)
93GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers7.5166Citations (PDF)
94Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases6.3192Citations (PDF)
95Domain‐specific cognitive impairment in non‐demented Parkinson's disease psychosis2.211Citations (PDF)
96Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias2.618Citations (PDF)
97Onset and Remission of Psychosis in Parkinson's Disease: Pharmacologic and Motoric Markers1.510Citations (PDF)
98Animal models of neurodegenerative diseases
Nature Neuroscience, 2018, 21, 1370-1379
17.0513Citations (PDF)
99Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease
Science, 2018, 362,
36.2441Citations (PDF)
100The PINK1 p.I368N Mutation Affects Protein Stability and Kinase Activity with Its Structural Change
Juntendo Medical Journal, 2018, 64, 17-30
0.20Citations (PDF)
101Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease
Cell Metabolism, 2018, 28, 588-604.e5
25.2254Citations (PDF)
102α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism14.1181Citations (PDF)
103Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration14.198Citations (PDF)
104Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease2.643Citations (PDF)
105Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
Nature Medicine, 2018, 24, 931-938
33.0993Citations (PDF)
106Neurotoxic reactive astrocytes are induced by activated microglia
Nature, 2017, 541, 481-487
37.96,890Citations (PDF)
107Mitochondrial Mechanisms of Neuronal Cell Death: Potential Therapeutics11.8151Citations (PDF)
108PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival
Cell Reports, 2017, 18, 918-932
6.3173Citations (PDF)
109Precision therapy for a new disorder of AMPA receptor recycling due to mutations in <i>ATAD1</i>2.848Citations (PDF)
110The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity14.170Citations (PDF)
111Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes
Experimental Neurology, 2017, 298, 191-201
4.064Citations (PDF)
112T cells from patients with Parkinson’s disease recognize α-synuclein peptides
Nature, 2017, 546, 656-661
37.9803Citations (PDF)
113Activation mechanisms of the E3 ubiquitin ligase parkin
Biochemical Journal, 2017, 474, 3075-3086
3.852Citations (PDF)
114Toward the human cellular microRNAome
Genome Research, 2017, 27, 1769-1781
4.6165Citations (PDF)
115Two approaches reveal a new paradigm of ‘switchable or genetics-influenced allele-specific DNA methylation’ with potential in human disease
Cell Discovery, 2017, 3,
7.926Citations (PDF)
116Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism
Brain, 2017, 140, 98-117
8.4129Citations (PDF)
117Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis4.728Citations (PDF)
118c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential3.384Citations (PDF)
119Overexpression of Parkinson’s Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology
ENeuro, 2017, 4, ENEURO.0004-17.2017
2.137Citations (PDF)
120The NINDS Parkinson's disease biomarkers program
Movement Disorders, 2016, 31, 915-923
4.6107Citations (PDF)
121LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity2.042Citations (PDF)
122Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3
Science, 2016, 353,
36.2649Citations (PDF)
123Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomes2.623Citations (PDF)
124Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients2.68Citations (PDF)
125A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1
Science, 2016, 354,
36.2359Citations (PDF)
126LRRK2 pathobiology in Parkinson's disease – virtual inclusion
Journal of Neurochemistry, 2016, 139, 75-76
3.86Citations (PDF)
127Association of<i>GBA</i>Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease
JAMA Neurology, 2016, 73, 1217
17.6220Citations (PDF)
128Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB113.770Citations (PDF)
129Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity12.587Citations (PDF)
130Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies
Neurobiology of Disease, 2016, 94, 55-62
5.162Citations (PDF)
131Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 2016, 12, 1-222
13.74,989Citations (PDF)
132<i>GBA</i> Variants are associated with a distinct pattern of cognitive deficits in <scp>P</scp>arkinson's disease
Movement Disorders, 2016, 31, 95-102
4.6195Citations (PDF)
133Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration
Journal of Clinical Investigation, 2016, 126, 2970-2988
10.6166Citations (PDF)
134Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons
ENeuro, 2016, 3, ENEURO.0183-16.2016
2.195Citations (PDF)
135High-Content Genome-Wide RNAi Screen Reveals<i>CCR3</i>as a Key Mediator of Neuronal Cell Death
ENeuro, 2016, 3, ENEURO.0185-16.2016
2.119Citations (PDF)
136(Patho‐)physiological relevance of <scp>PINK</scp> 1‐dependent ubiquitin phosphorylation
EMBO Reports, 2015, 16, 1114-1130
5.2176Citations (PDF)
137Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity
PLoS ONE, 2015, 10, e0143854
2.317Citations (PDF)
138<i>PARK10</i> is a major locus for sporadic neuropathologically confirmed Parkinson disease
Neurology, 2015, 84, 972-980
1.050Citations (PDF)
139TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson’s disease via CNTF
Brain, 2015, 138, 3610-3622
8.4126Citations (PDF)
140Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration7.5240Citations (PDF)
141Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily
Human Molecular Genetics, 2014, 23, 2055-2077
2.9121Citations (PDF)
142Abberant protein synthesis in G2019S LRRK2<i>Drosophila</i>Parkinson disease-related phenotypes
Fly, 2014, 8, 165-169
2.120Citations (PDF)
143<scp>M</scp>sp1/<scp>ATAD</scp>1 maintains mitochondrial function by facilitating the degradation of mislocalized tail‐anchored proteins
EMBO Journal, 2014, 33, 1548-1564
7.3219Citations (PDF)
144Protein Microarray Characterization of the S-Nitrosoproteome3.058Citations (PDF)
145LRRK2 pathobiology in Parkinson's disease
Journal of Neurochemistry, 2014, 131, 554-565
3.8150Citations (PDF)
146Proneural Transcription Factor Atoh1 Drives Highly Efficient Differentiation of Human Pluripotent Stem Cells Into Dopaminergic Neurons4.143Citations (PDF)
147A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease
JAMA Neurology, 2014, 71, 543
17.6372Citations (PDF)
148Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson’s Disease
Cell, 2014, 157, 472-485
33.7265Citations (PDF)
149Parkin and PINK1: much more than mitophagy
Trends in Neurosciences, 2014, 37, 315-324
9.7341Citations (PDF)
150Early-onset Parkinson's disease due to PINK1 p.Q456X mutation – Clinical and functional study2.648Citations (PDF)
151Parkin‐independent mitophagy requires <scp>D</scp>rp1 and maintains the integrity of mammalian heart and brain
EMBO Journal, 2014, 33, 2798-2813
7.3414Citations (PDF)
152Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis7.5297Citations (PDF)
153Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder13.7144Citations (PDF)
154Ganglioside Regulation of AMPA Receptor Trafficking
Journal of Neuroscience, 2014, 34, 13246-13258
3.759Citations (PDF)
155MiR-223 regulates the differentiation of immature neurons0.029Citations (PDF)
156Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration
Neurobiology of Disease, 2014, 71, 345-358
5.171Citations (PDF)
157Parthanatos: mitochondrial‐linked mechanisms and therapeutic opportunities
British Journal of Pharmacology, 2014, 171, 2000-2016
6.3525Citations (PDF)
158The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease3.4223Citations (PDF)
159Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss
Nature Neuroscience, 2013, 16, 1392-1400
17.0207Citations (PDF)
160Reprogramming cellular events by poly(ADP-ribose)-binding proteins
Molecular Aspects of Medicine, 2013, 34, 1066-1087
9.4158Citations (PDF)
161Usp16: key controller of stem cells in Down syndrome
EMBO Journal, 2013, 32, 2788-2789
7.39Citations (PDF)
162New synaptic and molecular targets for neuroprotection in Parkinson's disease
Movement Disorders, 2013, 28, 51-60
4.638Citations (PDF)
163Sulfhydration mediates neuroprotective actions of parkin13.7320Citations (PDF)
164The interplay of microRNA and neuronal activity in health and disease3.452Citations (PDF)
165LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization
PLoS ONE, 2013, 8, e77198
2.373Citations (PDF)
166Linked Clinical Trials – The Development of New Clinical Learning Studies in Parkinson's Disease Using Screening of Multiple Prospective New Treatments3.339Citations (PDF)
167Nitric Oxide Synthase Inhibitors
CNS Drugs, 2012, 6, 351-357
6.30Citations (PDF)
168ArfGAP1 Is a GTPase Activating Protein for LRRK2: Reciprocal Regulation of ArfGAP1 by LRRK2
Journal of Neuroscience, 2012, 32, 3877-3886
3.798Citations (PDF)
169Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity
Human Molecular Genetics, 2012, 21, 163-174
2.938Citations (PDF)
170Animal Models of Parkinson's Disease: Vertebrate Genetics6.6106Citations (PDF)
171Neurodegenerative phenotypes in an A53T  -synuclein transgenic mouse model are independent of LRRK2
Human Molecular Genetics, 2012, 21, 2420-2431
2.996Citations (PDF)
172MicroRNA-223 is neuroprotective by targeting glutamate receptors7.5269Citations (PDF)
173Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease11.471Citations (PDF)
174Botch Promotes Neurogenesis by Antagonizing Notch
Developmental Cell, 2012, 22, 707-720
7.769Citations (PDF)
175Meta‐analysis of Parkinson's Disease: Identification of a novel locus, <i>RIT2</i>
Annals of Neurology, 2012, 71, 370-384
6.6288Citations (PDF)
176Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease12.5478Citations (PDF)
177Chemoproteomics-Based Design of Potent LRRK2-Selective Lead Compounds That Attenuate Parkinson’s Disease-Related Toxicity in Human Neurons
ACS Chemical Biology, 2011, 6, 1021-1028
3.7142Citations (PDF)
178PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
Cell, 2011, 144, 689-702
33.7901Citations (PDF)
179The AAA+ ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior
Cell, 2011, 145, 284-299
33.7104Citations (PDF)
180Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1–Dependent Cell Death (Parthanatos)5.4428Citations (PDF)
181MicroRNAs in Parkinson's disease2.0164Citations (PDF)
182Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
PLoS ONE, 2011, 6, e18568
2.3363Citations (PDF)
183Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death
Nature Medicine, 2011, 17, 692-699
33.0206Citations (PDF)
184Recent Advances in the Genetics of Parkinson's Disease6.7400Citations (PDF)
185A perfect “Match” for in vitro human disease modeling and autologous cell-based transplantation therapy: Generating genetically identical Parkinson's disease and control pluripotent stem cells by precise gene targeting
Movement Disorders, 2011, 26, 1804-1804
4.60Citations (PDF)
186Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage7.5251Citations (PDF)
187Enhanced Autophagy from Chronic Toxicity of Iron and Mutant A53T α-Synuclein
Journal of Biological Chemistry, 2011, 286, 33380-33389
2.285Citations (PDF)
188Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models
Human Molecular Genetics, 2011, 20, 3933-3942
2.9131Citations (PDF)
189Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
PLoS ONE, 2011, 6, e16706
2.361Citations (PDF)
190Neuronal Activity Regulates Hippocampal miRNA Expression
PLoS ONE, 2011, 6, e25068
2.350Citations (PDF)
191The role of parkin in familial and sporadic Parkinson's disease
Movement Disorders, 2010, 25,
4.6341Citations (PDF)
192Contributions of poly(ADP‐ribose) polymerase‐1 and ‐2 to nuclear translocation of apoptosis‐inducing factor and injury from focal cerebral ischemia
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202Functional Identification of Neuroprotective Molecules
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206Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease3.757Citations (PDF)
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210Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos
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211SnapShot: Pathogenesis of Parkinson's Disease
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214Role of Tuberin in Neuronal Degeneration
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218Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
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219Parkin mediates the degradation‐independent ubiquitination of Hsp70
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223The Chaperone Activity of Heat Shock Protein 90 Is Critical for Maintaining the Stability of Leucine-Rich Repeat Kinase 2
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226Ataxia Telangiectasia Mutated (ATM) Signaling Network Is Modulated by a Novel Poly(ADP-ribose)-dependent Pathway in the Early Response to DNA-damaging Agents
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229Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
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237A Nitric Oxide Signaling Pathway Controls CREB-Mediated Gene Expression in Neurons
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382Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants
Brain Research, 1991, 540, 145-152
2.522Citations (PDF)
383Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase
Neuron, 1991, 7, 615-624
11.01,402Citations (PDF)
384Thrombotic microangiopathy isolated to the central nervous system
Annals of Neurology, 1991, 30, 843-846
6.62Citations (PDF)
385Muscarinic and dopaminergic receptor subtypes on striatal cholinergic interneurons
Brain Research Bulletin, 1990, 25, 903-912
3.437Citations (PDF)
386Decreased beta-adrenergic receptors in rat brain after chronic administration of the selective serotonin uptake inhibitor fluoxetine
Psychopharmacology, 1988, 94, 141-143
2.862Citations (PDF)
387Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen
Life Sciences, 1988, 42, 1933-1939
4.580Citations (PDF)
388Localization of nigrostriatal dopamine receptor subtypes and adenylate cyclase
Brain Research Bulletin, 1988, 20, 447-459
3.469Citations (PDF)
389Dopamine D-2 auto- and postsynaptic receptors in the nigrostriatal system of the rat brain: localization by quantitative autoradiography with [3H]sulpiride4.370Citations (PDF)
390Presynaptic and postsynaptic D1 dopamine receptors in the nigrostriatal system of the rat brain: a quantitative autoradiographic study using the selective D1 antagonist [3H]SCH 23390
Brain Research, 1987, 408, 205-209
2.584Citations (PDF)
391Chronic administration of sertraline, a selective serotonin uptake inhibitor, decreased the density of β-adrenergic receptors in rat frontoparietal cortex
Brain Research, 1987, 421, 377-381
2.530Citations (PDF)
392Evidence that [3H]forskolin binding in the substantia nigra is intrinsic to a striatal-nigral projection: An autoradiographic study of rat brain
Neuroscience Letters, 1987, 73, 114-118
1.927Citations (PDF)
393Autoradiographic Evidence of [3H]SCH 23390 Binding Site; in Human Prefrontal Cortex (Brodmann's Area 9)
Journal of Neurochemistry, 1987, 49, 789-796
3.834Citations (PDF)
394Quantitative autoradiographic localization of D-1 dopamine receptors in the rat brain: Use of the iodinated ligand [125I]SCH 23982
Neuroscience Letters, 1986, 68, 261-266
1.954Citations (PDF)
395Quantitative autoradiographic evidence for axonal transport of imipramine receptors in the central nervous system of the rat
Neuroscience Letters, 1985, 55, 261-266
1.932Citations (PDF)
396Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa
ELife, 0, 10,
1.624Citations (PDF)
397Title is missing!
0
3Citations (PDF)
398Lewy body dementia promotion by air pollutants
Science, 0, 389,
36.217Citations (PDF)