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315 peer-reviewed articles • 15,436 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B13.26Citations (PDF)
2Physiologically based pharmacokinetics modeling and transporter proteomics to predict systemic and local liver and muscle disposition of statins2.77Citations (PDF)
3Barcode lipids for absolute quantitation of liposomes in ocular tissues11.07Citations (PDF)
4Transporter Protein Expression of Corneal Epithelium in Rabbit and Porcine: Evaluation of Models for Ocular Drug Transport Study
Molecular Pharmaceutics, 2024, 21, 3204-3217
4.25Citations (PDF)
5Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs
Molecular Pharmaceutics, 2023, 20, 1331-1346
4.28Citations (PDF)
6Characterization of proteome profile data of chemicals based on data-independent acquisition MS with SWATH method2.21Citations (PDF)
7Selective drug delivery to the retinal cells: Biological barriers and avenues11.059Citations (PDF)
8Activation of Annexin A2 signaling at the blood–brain barrier in a mouse model of multiple sclerosis
Journal of Neurochemistry, 2022, 160, 662-674
3.825Citations (PDF)
9A human blood–arachnoid barrier atlas of transporters, receptors, enzymes, and tight junction and marker proteins: Comparison with dog and pig in absolute abundance
Journal of Neurochemistry, 2022, 161, 187-208
3.816Citations (PDF)
10Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery
Pharmaceutical Research, 2022, 39, 1363-1392
3.740Citations (PDF)
11Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs
Pharmaceutical Research, 2022, 39, 1393-1413
3.710Citations (PDF)
12Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier
Pharmaceutics, 2022, 14, 1683
4.916Citations (PDF)
13Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells
Cells, 2022, 11, 3963
4.619Citations (PDF)
14Development of Novel Methodology and Its Application for Clarifying the Transport Function of the Blood-brain Barrier
Yakugaku Zasshi, 2021, 141, 447-462
0.20Citations (PDF)
15Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia1.519Citations (PDF)
16An Atlas of the Quantitative Protein Expression of Anti-Epileptic-Drug Transporters, Metabolizing Enzymes and Tight Junctions at the Blood–Brain Barrier in Epileptic Patients
Pharmaceutics, 2021, 13, 2122
4.917Citations (PDF)
17Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood–brain barrier4.742Citations (PDF)
18Developmental changes in transporter and receptor protein expression levels at the rat blood-brain barrier based on quantitative targeted absolute proteomics2.128Citations (PDF)
19Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood–brain barrier transporters4.722Citations (PDF)
20Targeted Proteomics-Based Quantitative Protein Atlas of Pannexin and Connexin Subtypes in Mouse and Human Tissues and Cancer Cell Lines3.27Citations (PDF)
21Distinct Transport Properties of Human Pannexin 1 and Connexin 32 Hemichannels3.21Citations (PDF)
22Polarized hemichannel opening of pannexin 1/connexin 43 contributes to dysregulation of transport function in blood-brain barrier endothelial cells
Neurochemistry International, 2020, 132, 104600
3.517Citations (PDF)
23Abundant Expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1, and xCT Transporters in Blood-Arachnoid Barrier of Pig and Polarized Localizations at CSF- and Blood-Facing Plasma Membranes3.645Citations (PDF)
24The Multipotential of Leucine-Rich α-2 Glycoprotein 1 as a Clinicopathological Biomarker of Glioblastoma1.814Citations (PDF)
25Establishment and validation of highly accurate formalin-fixed paraffin-embedded quantitative proteomics by heat-compatible pressure cycling technology using phase-transfer surfactant and SWATH-MS
Scientific Reports, 2020, 10,
3.425Citations (PDF)
26Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR‐654‐5p and miR‐450b‐5p
Cancer Science, 2020, 111, 2413-2422
3.929Citations (PDF)
27Comparison of Absolute Protein Abundances of Transporters and Receptors among Blood–Brain Barriers at Different Cerebral Regions and the Blood–Spinal Cord Barrier in Humans and Rats
Molecular Pharmaceutics, 2020, 17, 2006-2020
4.270Citations (PDF)
28Determination of Intrinsic Creatine Transporter (Slc6a8) Activity and Creatine Transport Function of Leukocytes in Rats1.54Citations (PDF)
29Quantification of ENT1 and ENT2 Proteins at the Placental Barrier and Contribution of These Transporters to Ribavirin Uptake3.212Citations (PDF)
30Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood–Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein1.511Citations (PDF)
31Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells
Journal of Neurochemistry, 2019, 150, 385-401
3.818Citations (PDF)
32Increased Expression of Renal Drug Transporters in a Mouse Model of Familial Alzheimer's Disease3.214Citations (PDF)
33Organic Anion-Transporting Polypeptide 1a4 (Oatp1a4/Slco1a4) at the Blood–Arachnoid Barrier is the Major Pathway of Sulforhodamine-101 Clearance from Cerebrospinal Fluid of Rats
Molecular Pharmaceutics, 2019, 16, 2021-2027
4.224Citations (PDF)
34Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters
2019, 60, 5022
26Citations (PDF)
35Identification of Blood–Brain Barrier-Permeable Proteins Derived from a Peripheral Organ: In Vivo and in Vitro Evidence of Blood-to-Brain Transport of Creatine Kinase
Molecular Pharmaceutics, 2019, 16, 247-257
4.25Citations (PDF)
36Cluster of Differentiation 46 Is the Major Receptor in Human Blood–Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28)
Molecular Pharmaceutics, 2019, 16, 292-304
4.282Citations (PDF)
37[OPINION]Towards A New Sunrise in the Brain Drug Delivery Research
Drug Delivery System, 2019, 34, 334-334
0.10Citations (PDF)
38Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus3.629Citations (PDF)
39Drug Clearance from Cerebrospinal Fluid Mediated by Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) at Arachnoid Membrane of Rats
Molecular Pharmaceutics, 2018, 15, 911-922
4.240Citations (PDF)
40Gene therapy for Glut1‐deficient mouse using an adeno‐associated virus vector with the human intrinsic GLUT1 promoter2.428Citations (PDF)
41ATP-Binding Cassette Transporter A Subfamily 8 Is a Sinusoidal Efflux Transporter for Cholesterol and Taurocholate in Mouse and Human Liver
Molecular Pharmaceutics, 2018, 15, 343-355
4.226Citations (PDF)
42Gene expression of A6-like subgroup of ATP-binding cassette transporters in mouse brain parenchyma and microvessels1.56Citations (PDF)
43High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human
Molecular Pharmaceutics, 2018, 15, 127-140
4.234Citations (PDF)
44Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier
Drug Metabolism and Disposition, 2018, 46, 1767-1775
3.616Citations (PDF)
45Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease
Molecular Pharmaceutics, 2018, 15, 4073-4083
4.228Citations (PDF)
46Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis
Molecular Neurobiology, 2018, 56, 2039-2056
3.792Citations (PDF)
47Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics
PLoS ONE, 2018, 13, e0193799
2.3106Citations (PDF)
48Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome1.216Citations (PDF)
49Actin filament‐associated protein 1 (AFAP‐1) is a key mediator in inflammatory signaling‐induced rapid attenuation of intrinsic P‐gp function in human brain capillary endothelial cells
Journal of Neurochemistry, 2017, 141, 247-262
3.823Citations (PDF)
50LC–MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line
Molecular Pharmaceutics, 2017, 14, 605-613
4.248Citations (PDF)
51Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics
Journal of Proteomics, 2017, 158, 31-42
2.447Citations (PDF)
52All-trans retinoic acid enhances gemcitabine cytotoxicity in human pancreatic cancer cell line AsPC-1 by up-regulating protein expression of deoxycytidine kinase4.317Citations (PDF)
53Application of Quantitative Targeted Absolute Proteomics to Profile Protein Expression Changes of Hepatic Transporters and Metabolizing Enzymes During Cholic Acid-Promoted Liver Regeneration3.28Citations (PDF)
54Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs3.230Citations (PDF)
55MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells
Pancreas, 2017, 46, 557-566
0.99Citations (PDF)
56Scrambled Internal Standard Method for High-Throughput Protein Quantification by Matrix-Assisted Laser Desorption Ionization Tandem Mass Spectrometry
Journal of Proteome Research, 2017, 16, 1556-1565
3.47Citations (PDF)
57The blood‐brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transport
Journal of Neurochemistry, 2017, 141, 400-412
3.863Citations (PDF)
58Inner Blood–Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig
Molecular Pharmaceutics, 2017, 14, 3729-3738
4.229Citations (PDF)
59Quantification of Transporter and Receptor Proteins in Dog Brain Capillaries and Choroid Plexus: Relevance for the Distribution in Brain and CSF of Selected BCRP and P-gp Substrates
Molecular Pharmaceutics, 2017, 14, 3436-3447
4.256Citations (PDF)
60Quantitative Targeted Absolute Proteomics (QTAP)-based Pharmacoproteomics: The Importance of International Collaboration
Yakugaku Zasshi, 2017, 137, 685-689
0.20Citations (PDF)
61Abnormal <i>N</i>-Glycosylation of a Novel Missense Creatine Transporter Mutant, G561R, Associated with Cerebral Creatine Deficiency Syndromes Alters Transporter Activity and Localization1.514Citations (PDF)
62Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain
Neurochemical Research, 2017, 43, 500-510
3.411Citations (PDF)
63Large‐scale multiplex absolute protein quantification of drug‐metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH‐MS: Comparison with MRM/SRM and HR‐MRM/PRM
Proteomics, 2016, 16, 2106-2117
3.1126Citations (PDF)
64Correlation of Organic Cation/Carnitine Transporter 1 and Multidrug Resistance-Associated Protein 1 Transport Activities With Protein Expression Levels in Primary Cultured Human Tracheal, Bronchial, and Alveolar Epithelial Cells3.218Citations (PDF)
65Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects
Molecular Pharmaceutics, 2016, 13, 2631-2640
4.276Citations (PDF)
66Global and Targeted Proteomics of Prostate Cancer Cell Secretome: Combination of 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry and In Silico Selection Selected Reaction Monitoring Analysis3.212Citations (PDF)
67Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine
Molecular Pharmaceutics, 2016, 13, 2443-2456
4.218Citations (PDF)
68Oral Morphine Pharmacokinetic in Obesity: The Role of P-Glycoprotein, MRP2, MRP3, UGT2B7, and CYP3A4 Jejunal Contents and Obesity-Associated Biomarkers
Molecular Pharmaceutics, 2016, 13, 766-773
4.226Citations (PDF)
69Identification of IGFBP2 and IGFBP3 As Compensatory Biomarkers for CA19-9 in Early-Stage Pancreatic Cancer Using a Combination of Antibody-Based and LC-MS/MS-Based Proteomics
PLoS ONE, 2016, 11, e0161009
2.395Citations (PDF)
70Quantitative Determination of Luminal and Abluminal Membrane Distributions of Transporters in Porcine Brain Capillaries by Plasma Membrane Fractionation and Quantitative Targeted Proteomics3.277Citations (PDF)
71Quantitative targeted absolute proteomics of rat blood–cerebrospinal fluid barrier transporters: comparison with a human specimen
Journal of Neurochemistry, 2015, 134, 1104-1115
3.8102Citations (PDF)
72Major involvement of Na+‐dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells
Journal of Neurochemistry, 2015, 134, 97-112
3.8111Citations (PDF)
73Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport
PLoS ONE, 2015, 10, e0118638
2.333Citations (PDF)
74Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells3.340Citations (PDF)
75Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (Calu-3 and BEAS2-B), Bronchiolar–Alveolar Cells (NCI-H292 and NCI-H441), and Alveolar Type II-like Cells (A549) by Liquid Chromatography–Tandem Mass Spectrometry3.248Citations (PDF)
76Quantitative Targeted Proteomics of Pancreatic Cancer: Deoxycytidine Kinase Protein Level Correlates to Progression-Free Survival of Patients Receiving Gemcitabine Treatment
Molecular Pharmaceutics, 2015, 12, 3282-3291
4.240Citations (PDF)
77Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks2.143Citations (PDF)
78Involvement of Insulin-Degrading Enzyme in Insulin- and Atrial Natriuretic Peptide-Sensitive Internalization of Amyloid-β Peptide in Mouse Brain Capillary Endothelial Cells2.633Citations (PDF)
79Blood-Brain Barrier Pharmacoproteomics-Based Reconstruction of the In Vivo Brain Distribution of P-Glycoprotein Substrates in Cynomolgus Monkeys3.356Citations (PDF)
80Pharmacoproteomics-Based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-Kindled Epilepsy, Spontaneous Epilepsy, and Phenytoin Treatment Models
Drug Metabolism and Disposition, 2014, 42, 1719-1726
3.629Citations (PDF)
81Quantitative targeted proteomics for understanding the blood–brain barrier: towards pharmacoproteomics
Expert Review of Proteomics, 2014, 11, 303-313
2.044Citations (PDF)
82Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
Drug Metabolism and Disposition, 2014, 42, 1039-1043
3.642Citations (PDF)
83Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases
Pharmaceutical Research, 2014, 32, 2060-2071
3.730Citations (PDF)
84Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model5.372Citations (PDF)
85Contributions of Degradation and Brain-to-blood Elimination Across the Blood—Brain Barrier to Cerebral Clearance of Human Amyloid-β Peptide(1-40) in Mouse Brain4.718Citations (PDF)
86Identification of Transporters Associated with Etoposide Sensitivity of Stomach Cancer Cell Lines and Methotrexate Sensitivity of Breast Cancer Cell Lines by Quantitative Targeted Absolute Proteomics
Molecular Pharmacology, 2013, 83, 490-500
2.623Citations (PDF)
87Quantitative expression of human drug transporter proteins in lung tissues: Analysis of regional, gender, and interindividual differences by liquid chromatography–tandem mass spectrometry3.282Citations (PDF)
88Quantitative Targeted Absolute Proteomic Analysis of Transporters, Receptors and Junction Proteins for Validation of Human Cerebral Microvascular Endothelial Cell Line hCMEC/D3 as a Human Blood–Brain Barrier Model
Molecular Pharmaceutics, 2013, 10, 289-296
4.2221Citations (PDF)
89Blood-to-brain influx transport of nicotine at the rat blood?brain barrier: Involvement of a pyrilamine-sensitive organic cation transport process
Neurochemistry International, 2013, 62, 173-181
3.555Citations (PDF)
90Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: Implications for diabetic retinopathy
Experimental Cell Research, 2013, 319, 1001-1012
3.1108Citations (PDF)
91Quantitative Targeted Absolute Proteomics-Based Large-Scale Quantification of Proline-Hydroxylated α-Fibrinogen in Plasma for Pancreatic Cancer Diagnosis
Journal of Proteome Research, 2013, 12, 753-762
3.439Citations (PDF)
92Quantitative Atlas of Blood–Brain Barrier Transporters, Receptors, and Tight Junction Proteins in Rats and Common Marmoset3.2235Citations (PDF)
93Establishment and characterization of spinal cord microvascular endothelial cell lines1.023Citations (PDF)
94Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans
Human Molecular Genetics, 2013, 22, 578-592
2.981Citations (PDF)
95Quantitative targeted absolute proteomics (QTAP)-based rational research on the human blood-brain barrier transport
Drug Delivery System, 2013, 28, 270-278
0.10Citations (PDF)
96Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities3.6402Citations (PDF)
97Absolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human Hepatocytes3.6128Citations (PDF)
98Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice
Drug Metabolism and Disposition, 2012, 40, 1164-1169
3.6120Citations (PDF)
99Attenuation of Phosphorylation by Deoxycytidine Kinase is Key to Acquired Gemcitabine Resistance in a Pancreatic Cancer Cell Line: Targeted Proteomic and Metabolomic Analyses in PK9 Cells
Pharmaceutical Research, 2012, 29, 2006-2016
3.723Citations (PDF)
100Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics3.111Citations (PDF)
101Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels
Molecular Pharmaceutics, 2011, 8, 1332-1341
4.2355Citations (PDF)
102GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy4.126Citations (PDF)
103Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice3.3125Citations (PDF)
104In-vivo Blood-brain Barrier Transport of a Novel Adrenocorticotropic Hormone Analogue, Ebiratide, Demonstrated by Brain Microdialysis and Capillary Depletion Methods2.94Citations (PDF)
105Experimental evidence of characteristic tissue distribution of adriamycin. Tissue DNA concentration as a determinant2.914Citations (PDF)
106Specific binding and clearance of [3H]dynorphin (1–13) in the perfused rat lung: an application of the multiple-indicator dilution method2.93Citations (PDF)
107Physiological pharmacokinetics of Mactam antibiotics: penicillin V distribution and elimination after intravenous administration in rats2.96Citations (PDF)
108In-vitro Evidence for Carrier-mediated Uptake of Acidic Drugs by Isolated Bovine Brain Capillaries2.93Citations (PDF)
109A carrier-mediated transport system for benzylpenicillin in isolated hepatocytes2.91Citations (PDF)
110Intestinal brush-border transport of the oral cephalosporin antibiotic, cefdinir, mediated by dipeptide and monocarboxylic acid transport systems in rabbits2.914Citations (PDF)
111Molecular-weight-dependent, Anionic-substrate-preferential Transport of β-Lactam Antibiotics via Multidrug Resistance-associated Protein 42.130Citations (PDF)
112Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors
Journal of Neurochemistry, 2011, 117, 333-345
3.8801Citations (PDF)
113Amyloid‐β peptide(1‐40) elimination from cerebrospinal fluid involves low‐density lipoprotein receptor‐related protein 1 at the blood‐cerebrospinal fluid barrier
Journal of Neurochemistry, 2011, 118, 407-415
3.857Citations (PDF)
114Atrial Natriuretic Peptide is Eliminated from the Brain by Natriuretic Peptide Receptor-C-Mediated Brain-to-Blood Efflux Transport at the Blood—Brain Barrier4.718Citations (PDF)
115Attenuation of prostaglandin E2 elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole5.338Citations (PDF)
116Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals
Analytical Biochemistry, 2011, 418, 276-285
2.456Citations (PDF)
117Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system
BMC Neuroscience, 2011, 12,
2.128Citations (PDF)
1181α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier5.394Citations (PDF)
119Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection3.2160Citations (PDF)
120Quantitative Membrane Protein Expression at the Blood–Brain Barrier of Adult and Younger Cynomolgus Monkeys3.2215Citations (PDF)
121Diphenhydramine Active Uptake at the Blood–Brain Barrier and Its Interaction with Oxycodone in vitro and in Vivo3.289Citations (PDF)
122Reliability and Robustness of Simultaneous Absolute Quantification of Drug Transporters, Cytochrome P450 Enzymes, and Udp-Glucuronosyltransferases in Human Liver Tissue by Multiplexed MRM/Selected Reaction Monitoring Mode Tandem Mass Spectrometry with Nano-Liquid Chromatography3.256Citations (PDF)
123Functional characterization of Rat Plasma Membrane Monoamine Transporter in the Blood–Brain and Blood–Cerebrospinal Fluid Barriers3.243Citations (PDF)
124Quantitative Targeted Absolute Proteomics-Based Adme Research as A New Path to Drug Discovery and Development: Methodology, Advantages, Strategy, and Prospects3.2129Citations (PDF)
125Inner Blood–Retinal Barrier Mediates L-Isomer-Predominant Transport of Serine3.211Citations (PDF)
126Peripheral nerve pericytes modify the blood–nerve barrier function and tight junctional molecules through the secretion of various soluble factors
Journal of Cellular Physiology, 2011, 226, 255-266
4.1134Citations (PDF)
127Saturable uptake of cefixime, a new oral cephalosporin without an α-amino group, by the rat intestine2.910Citations (PDF)
128Expression of ABC-type transport proteins in human platelets1.233Citations (PDF)
129Regulation of extracellular-superoxide dismutase in rat retina pericytes
Redox Report, 2010, 15, 250-258
6.210Citations (PDF)
130Epidermal growth factor targeting of bacteriophage to the choroid plexus for gene delivery to the central nervous system via cerebrospinal fluid
Brain Research, 2010, 1359, 1-13
2.511Citations (PDF)
131Drug–drug interaction between oxycodone and adjuvant analgesics in blood–brain barrier transport and antinociceptive effect3.222Citations (PDF)
132Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood–brain barrier function
Journal of Cellular Physiology, 2010, 225, 519-528
4.1115Citations (PDF)
133Lack of brain‐to‐blood efflux transport activity of low‐density lipoprotein receptor‐related protein‐1 (LRP‐1) for amyloid‐β peptide(1–40) in mouse: involvement of an LRP‐1‐independent pathway
Journal of Neurochemistry, 2010, 113, 1356-1363
3.847Citations (PDF)
134Is P-glycoprotein Involved in Amyloid-β Elimination Across the Blood–Brain Barrier in Alzheimer’s Disease?4.720Citations (PDF)
135Involvement of Multidrug Resistance-Associated Protein 4 in Efflux Transport of Prostaglandin E2 across Mouse Blood-Brain Barrier and Its Inhibition by Intravenous Administration of Cephalosporins3.335Citations (PDF)
136The HMG-CoA Reductase Inhibitor Pravastatin Stimulates Insulin Secretion through Organic Anion Transporter Polypeptides2.121Citations (PDF)
137Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy
Cell Death and Disease, 2010, 1, e65-e65
8.5130Citations (PDF)
138In-vivo and In-vitro Evidence of a Carrier-mediated Efflux Transport System for Oestrone-3-sulphate across the Blood-Cerebrospinal Fluid Barrier2.915Citations (PDF)
139Characterization of immortalized choroid plexus epithelial cell lines for studies of transport processes across the blood-cerebrospinal fluid barrier2.328Citations (PDF)
140Polyol Formation in Cell Lines of Rat Retinal Capillary Pericytes and Endothelial Cells (TR-rPCT and TR-iBRB)1.916Citations (PDF)
141Depletion of Vitamin E Increases Amyloid β Accumulation by Decreasing Its Clearances from Brain and Blood in a Mouse Model of Alzheimer Disease
Journal of Biological Chemistry, 2009, 284, 33400-33408
2.299Citations (PDF)
142Human Platelets Express Organic Anion-Transporting Peptide 2B1, an Uptake Transporter for Atorvastatin
Drug Metabolism and Disposition, 2009, 37, 1129-1137
3.661Citations (PDF)
143Roles of Inner Blood-Retinal Barrier Organic Anion Transporter 3 in the Vitreous/Retina-to-Blood Efflux Transport of p-Aminohippuric Acid, Benzylpenicillin, and 6-Mercaptopurine3.367Citations (PDF)
144SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation0.4137Citations (PDF)
145Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
Journal of Cellular Physiology, 2009, 221, 262-272
4.1232Citations (PDF)
146The blood–brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters
Journal of Neurochemistry, 2009, 111, 499-509
3.850Citations (PDF)
147Beneficial Effects of Estrogen in a Mouse Model of Cerebrovascular Insufficiency
PLoS ONE, 2009, 4, e5159
2.336Citations (PDF)
148mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting
Journal of Neurochemistry, 2008, 104, 147-154
3.8144Citations (PDF)
149Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria
Pharmaceutical Research, 2008, 25, 1469-1483
3.7467Citations (PDF)
150Characterization of the Mechanism of Zidovudine Uptake by Rat Conditionally Immortalized Syncytiotrophoblast Cell Line TR-TBT
Pharmaceutical Research, 2008, 25, 1647-1653
3.722Citations (PDF)
151Efflux of a suppressive neurotransmitter, GABA, across the blood-brain barrier
Journal of Neurochemistry, 2008, 79, 110-118
3.882Citations (PDF)
152Peripheral Nerve pericytes originating from the blood–nerve barrier expresses tight junctional molecules and transporters as barrier‐forming cells
Journal of Cellular Physiology, 2008, 217, 388-399
4.1104Citations (PDF)
153The blood‐cerebrospinal fluid barrier is a major pathway of cerebral creatinine clearance: involvement of transporter‐mediated process
Journal of Neurochemistry, 2008, 107, 432-442
3.836Citations (PDF)
154Expression and possible role of creatine transporter in the brain and at the blood‐cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant
Journal of Neurochemistry, 2008, 107, 768-778
3.857Citations (PDF)
155Fgf2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus epithelial cell behaviour2.319Citations (PDF)
156BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood–brain-barrier2.254Citations (PDF)
157Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood–brain barrier
Neurochemistry International, 2008, 52, 669-674
3.548Citations (PDF)
158ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier
Neurochemistry International, 2008, 52, 956-961
3.551Citations (PDF)
159Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) on Pharmacokinetics and Central Nervous System Penetration of Abacavir and Zidovudine in the Mouse
Drug Metabolism and Disposition, 2008, 36, 1476-1484
3.667Citations (PDF)
160The Low Density Lipoprotein Receptor-related Protein 1 Mediates Uptake of Amyloid β Peptides in an in Vitro Model of the Blood-Brain Barrier Cells
Journal of Biological Chemistry, 2008, 283, 34554-34562
2.2111Citations (PDF)
161Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone
Drug Metabolism and Disposition, 2008, 36, 2005-2013
3.6176Citations (PDF)
162Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1
Drug Metabolism and Disposition, 2008, 36, 2080-2085
3.617Citations (PDF)
163Altered Expression of Basement Membrane-related Molecules in Rat Brain Pericyte, Endothelial, and Astrocyte Cell Lines after Transforming Growth Factor-β1 Treatment2.133Citations (PDF)
164Insulin Facilitates the Hepatic Clearance of Plasma Amyloid β-Peptide (1–40) by Intracellular Translocation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP-1) to the Plasma Membrane in Hepatocytes
Molecular Pharmacology, 2007, 72, 850-855
2.6115Citations (PDF)
165Function and regulation of taurine transport at the inner blood–retinal barrier
Microvascular Research, 2007, 73, 100-106
2.569Citations (PDF)
166Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro3.557Citations (PDF)
167Inducible Nitric Oxide Synthase Isoform Is a Key Mediator of Leukostasis and Blood-Retinal Barrier Breakdown in Diabetic Retinopathy
2007, 48, 5257
235Citations (PDF)
168Exogenous expression of claudin-5 induces barrier properties in cultured rat brain capillary endothelial cells4.1164Citations (PDF)
16924S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression
Journal of Neurochemistry, 2007, 100, 968-978
3.864Citations (PDF)
170Brain‐to‐blood elimination of 24S‐hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood–brain barrier
Journal of Neurochemistry, 2007, 103, 1430-1438
3.838Citations (PDF)
171Cerebral clearance of human amyloid‐β peptide (1–40) across the blood–brain barrier is reduced by self‐aggregation and formation of low‐density lipoprotein receptor‐related protein‐1 ligand complexes
Journal of Neurochemistry, 2007, 103, 2482-2490
3.881Citations (PDF)
172A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters
Brain Research, 2007, 1150, 1-13
2.5153Citations (PDF)
173Establishing a Method to Isolate Rat Brain Capillary Endothelial Cells by Magnetic Cell Sorting and Dominant mRNA Expression of Multidrug Resistance-associated Protein 1 and 4 in Highly Purified Rat Brain Capillary Endothelial Cells
Pharmaceutical Research, 2007, 24, 688-694
3.732Citations (PDF)
174Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development
Pharmaceutical Research, 2007, 24, 1745-1758
3.7461Citations (PDF)
175Multichannel Liquid Chromatography–Tandem Mass Spectrometry Cocktail Method for Comprehensive Substrate Characterization of Multidrug Resistance-Associated Protein 4 Transporter
Pharmaceutical Research, 2007, 24, 2281-2296
3.766Citations (PDF)
176Induction of Endoplasmic Reticulum Stress in Retinal Pericytes by Glucose Deprivation
Current Eye Research, 2006, 31, 947-953
2.180Citations (PDF)
177In vivo delivery of small interfering RNA targeting brain capillary endothelial cells2.133Citations (PDF)
178Functional characterization of the brain-to-blood efflux clearance of human amyloid-β peptide (1–40) across the rat blood–brain barrier
Neuroscience Research, 2006, 56, 246-252
2.1116Citations (PDF)
179Modulation and Compensation of the mRNA Expression of Energy Related Transporters in the Brain of Glucose Transporter 1-Deficient Mice1.533Citations (PDF)
180Involvement of organic anion transporters in the efflux of uremic toxins across the blood–brain barrier
Journal of Neurochemistry, 2006, 96, 1051-1059
3.859Citations (PDF)
181ATP-Binding Cassette Transporter G2 Mediates the Efflux of Phototoxins on the Luminal Membrane of Retinal Capillary Endothelial Cells
Pharmaceutical Research, 2006, 23, 1235-1242
3.774Citations (PDF)
182Establishment and characterization of conditionally immortalized endothelial cell lines from the thoracic duct and inferior vena cava of tsA58/EGFP double-transgenic rats
Cell and Tissue Research, 2006, 326, 749-758
2.722Citations (PDF)
183Retinal-specific ATP-binding cassette transporter (ABCR/ABCA4) is expressed at the choroid plexus in rat brain
Journal of Neurochemistry, 2005, 92, 1277-1280
3.828Citations (PDF)
184Selective gene silencing of rat ATP-binding cassette G2 transporter in an in vitro blood-brain barrier model by short interfering RNA
Journal of Neurochemistry, 2005, 93, 63-71
3.815Citations (PDF)
185Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain
Journal of Neurochemistry, 2005, 95, 294-304
3.8130Citations (PDF)
186PKC/MAPK signaling suppression by retinal pericyte conditioned medium prevents retinal endothelial cell proliferation
Journal of Cellular Physiology, 2005, 203, 378-386
4.116Citations (PDF)
187Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; Comparison of gene expression between the blood-brain and -retinal barriers
Journal of Cellular Physiology, 2005, 204, 896-900
4.139Citations (PDF)
188Platelet‐derived growth factor‐BB (PDGF‐BB) induces differentiation of bone marrow endothelial progenitor cell‐derived cell line TR‐BME2 into mural cells, and changes the phenotype
Journal of Cellular Physiology, 2005, 204, 948-955
4.145Citations (PDF)
189Evidence for creatine biosynthesis in Müller glia
Glia, 2005, 52, 47-52
5.043Citations (PDF)
190Donepezil, tacrine and α-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB)6.931Citations (PDF)
191Differential Contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in Vivo Renal Uptake of Uremic Toxins in Rats
Pharmaceutical Research, 2005, 22, 619-627
3.755Citations (PDF)
192Vascular EndotheliumSelective Gene Induction by Tie2 Promoter/Enhancer in the Brain and Retina of a Transgenic Rat
Pharmaceutical Research, 2005, 22, 852-857
3.718Citations (PDF)
193L-Type Amino Acid Transporter 1–Mediatedl-Leucine Transport at the Inner Blood–Retinal Barrier
2005, 46, 2522
93Citations (PDF)
194Increased JNK Phosphorylation and Oxidative Stress in Response to Increased Glucose Flux through Increased GLUT1 Expression in Rat Retinal Endothelial Cells
2005, 46, 3403
23Citations (PDF)
195Pharmacokinetic simulator with three-dimensional graphical models: Sociotechnological interface of pharmacokinetics for medical personnel, patients, and medicinal chemists
International Congress Series, 2005, 1284, 296-301
0.20Citations (PDF)
196Physiological pharmacokinetics and membrane transport for drug delivery research
International Congress Series, 2005, 1284, 266-273
0.20Citations (PDF)
197Characterization of the organic cation transporter SLC22A16: A doxorubicin importer2.1147Citations (PDF)
198In vitro models for the blood–brain barrier
Toxicology in Vitro, 2005, 19, 299-334
2.6386Citations (PDF)
199Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: An overview of biology and methodology
NeuroRx, 2005, 2, 63-72
3.475Citations (PDF)
200Blood-Brain Barrier Permeability of Novel [d-Arg2]Dermorphin (1-4) Analogs: Transport Property Is Related to the Slow Onset of Antinociceptive Activity in the Central Nervous System3.318Citations (PDF)
201Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier
Journal of Cell Science, 2004, 117, 5071-5078
2.4150Citations (PDF)
202Brain Insulin Impairs Amyloid- (1-40) Clearance from the Brain
Journal of Neuroscience, 2004, 24, 9632-9637
3.797Citations (PDF)
203Mouse Reduced in Osteosclerosis Transporter Functions as an Organic Anion Transporter 3 and Is Localized at Abluminal Membrane of Blood-Brain Barrier3.377Citations (PDF)
204Vitamin C Transport in Oxidized Form across the Rat Blood–Retinal Barrier
2004, 45, 1232
93Citations (PDF)
205Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK‐Mi and CK‐B suggest a novel neuron–glial relationship for brain energy homeostasis3.5159Citations (PDF)
206A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro
Journal of Neurochemistry, 2004, 89, 503-513
3.8327Citations (PDF)
207Blood‐to‐retina transport of creatine via creatine transporter (CRT) at the rat inner blood–retinal barrier
Journal of Neurochemistry, 2004, 89, 1454-1461
3.862Citations (PDF)
208Localization of organic anion transporting polypeptide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells
Journal of Neurochemistry, 2004, 90, 743-749
3.854Citations (PDF)
209Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs
Journal of Neurochemistry, 2004, 90, 931-941
3.881Citations (PDF)
210Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
Journal of Neurochemistry, 2004, 90, 526-536
3.8136Citations (PDF)
211A new in vitro model for blood?cerebrospinal fluid barrier transport studies: an immortalized choroid plexus epithelial cell line derived from the tsA58 SV40 large T-antigen gene transgenic rat
Advanced Drug Delivery Reviews, 2004, 56, 1875-1885
15.431Citations (PDF)
212The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood-brain barrier
Journal of Neurochemistry, 2004, 87, 891-901
3.861Citations (PDF)
213Transporter mRNA Expression in a Conditionally Immortalized Rat Small Intestine Epithelial Cell Line (TR-SIE)2.19Citations (PDF)
214New approaches to in vitro models of blood–brain barrier drug transport
Drug Discovery Today, 2003, 8, 944-954
6.6160Citations (PDF)
215Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells
Biochemical Pharmacology, 2003, 66, 1945-1952
5.133Citations (PDF)
216Expression and regulation of L-cystine transporter, system xc?, in the newly developed rat retinal M�ller cell line (TR-MUL)
Glia, 2003, 43, 208-217
5.090Citations (PDF)
217Rat brain pericyte cell lines expressing ?2-adrenergic receptor, angiotensin II receptor type 1A, klotho, and CXCR4 mRNAs despite having endothelial cell markers4.123Citations (PDF)
218Blood-brain barrier transport of a novel µ1-specific opioid peptide, H-Tyr-d-Arg-Phe-β-Ala-OH (TAPA)
Journal of Neurochemistry, 2003, 84, 1154-1161
3.835Citations (PDF)
219Rat Organic Anion Transporter 3 (rOAT3) is Responsible for Brain-to-Blood Efflux of Homovanillic Acid at the Abluminal Membrane of Brain Capillary Endothelial Cells4.7161Citations (PDF)
220In Vitro Study of the Functional Expression of Organic Anion Transporting Polypeptide 3 at Rat Choroid Plexus Epithelial Cells and Its Involvement in the Cerebrospinal Fluid-to-Blood Transport of Estrone-3-Sulfate
Molecular Pharmacology, 2003, 63, 532-537
2.663Citations (PDF)
221Molecular mechanisms of drug influx and efflux transport at the blood-brain barrier0.112Citations (PDF)
222Brain and Heart Specific Alteration of Methamphetamine (MAP) Distribution in MAP-Sensitized Rat.1.57Citations (PDF)
223Establishment of Conditionally Immortalized Rat Retinal Pericyte Cell Lines (TR-rPCT) and Their Application in a Co-culture System Using Retinal Capillary Endothelial Cell Line (TR-iBRB2)
Cell Structure and Function, 2003, 28, 145-153
3.841Citations (PDF)
224Rat Organic Anion Transporter 3 (rOAT3) Is Responsible for Brain-to-Blood Efflux of Homovanillic Acid at the Abluminal Membrane of Brain Capillary Endothelial Cells4.765Citations (PDF)
225ATA2 Is Predominantly Expressed as System A at the Blood-Brain Barrier and Acts as Brain-to-Blood Efflux Transport forl-Proline
Molecular Pharmacology, 2002, 61, 1289-1296
2.673Citations (PDF)
226Enhancement of l-Cystine Transport Activity and Its Relation to xCT Gene Induction at the Blood-Brain Barrier by Diethyl Maleate Treatment3.356Citations (PDF)
227mRNA Expression and Amino Acid Transport Characteristics of Cultured Human Brain Microvascular Endothelial Cells (hBME)2.123Citations (PDF)
228In Vivo Evidence for Brain-to-Blood Efflux Transport of Valproic Acid across the Blood–Brain Barrier
Microvascular Research, 2002, 63, 233-238
2.527Citations (PDF)
229Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells
Neuroscience Research, 2002, 44, 173-180
2.180Citations (PDF)
230Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-β1 and β-glycerophosphate3.936Citations (PDF)
231Polarized glucose transporters and mRNA expression properties in newly developed rat syncytiotrophoblast cell lines, TR-TBTs
Journal of Cellular Physiology, 2002, 193, 208-218
4.141Citations (PDF)
232Blood-Brain Barrier Is Involved in the Efflux Transport of a Neuroactive Steroid, Dehydroepiandrosterone Sulfate, via Organic Anion Transporting Polypeptide 2
Journal of Neurochemistry, 2002, 75, 1907-1916
3.8132Citations (PDF)
233Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain
Journal of Neurochemistry, 2002, 83, 57-66
3.8212Citations (PDF)
234Internalization of basic fibroblast growth factor at the mouse blood-brain barrier involves perlecan, a heparan sulfate proteoglycan
Journal of Neurochemistry, 2002, 83, 381-389
3.867Citations (PDF)
235Regulation of taurine transport at the blood-brain barrier by tumor necrosis factor-α, taurine and hypertonicity
Journal of Neurochemistry, 2002, 83, 1188-1195
3.8117Citations (PDF)
236Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney
Kidney International, 2002, 61, 1760-1768
5.3143Citations (PDF)
237Recent advances in the brain-to-blood efflux transport across the blood–brain barrier4.848Citations (PDF)
238Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation
Oncogene, 2002, 21, 8817-8829
6.559Citations (PDF)
239The Blood–Brain Barrier Creatine Transporter is a Major Pathway for Supplying Creatine to the Brain4.7186Citations (PDF)
240The Blood???Brain Barrier Creatine Transporter Is a Major Pathway for Supplying Creatine to the Brain4.760Citations (PDF)
241ATA2 Is Predominantly Expressed as System A at the Blood-Brain Barrier and Acts as Brain-to-Blood Efflux Transport forl-Proline
Molecular Pharmacology, 2002, 61, 1289-1296
2.63Citations (PDF)
242Conditionally Immortalized Retinal Capillary Endothelial Cell Lines (TR-iBRB) Expressing Differentiated Endothelial Cell Functions Derived from a Transgenic Rat
Experimental Eye Research, 2001, 72, 163-172
2.5149Citations (PDF)
243Activation of Carrier-Mediated Transport of l-Cystine at the Blood–Brain and Blood–Retinal Barriers in Vivo
Microvascular Research, 2001, 62, 136-142
2.533Citations (PDF)
244Acidic Amino Acid Transport Characteristics of a Newly Developed Conditionally Immortalized Rat Type 2 Astrocyte Cell Line (TR-AST).
Cell Structure and Function, 2001, 26, 197-203
3.830Citations (PDF)
245Conditionally Immortalized Cell Lines as a New In Vitro Model for the Study of Barrier Functions1.587Citations (PDF)
246Blood-Brain Barrier Produces Significant Efflux of L-Aspartic Acid but Not D-Aspartic Acid
Journal of Neurochemistry, 2001, 73, 1206-1211
3.889Citations (PDF)
247Title is missing!
Pharmaceutical Research, 2001, 18, 16-22
3.764Citations (PDF)
248Title is missing!
Pharmaceutical Research, 2001, 18, 9-15
3.719Citations (PDF)
249Title is missing!
Pharmaceutical Research, 2001, 18, 1669-1676
3.7104Citations (PDF)
250GAT2/BGT-1 as a System Responsible for the Transport of γ-Aminobutyric Acid at the Mouse Blood–Brain Barrier4.7178Citations (PDF)
251Brain-to-blood efflux transport of estrone-3-sulfate at the blood-brain barrier in rats
Life Sciences, 2000, 67, 2699-2711
4.537Citations (PDF)
252Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene
AAPS PharmSci, 2000, 2, 69-79
1.764Citations (PDF)
253mRNA Expression and Transport Characterization of Conditionally Immortalized Rat Brain Capillary Endothelial Cell Lines; a Newin vitroBBB Model for Drug Targeting
Journal of Drug Targeting, 2000, 8, 357-370
3.9107Citations (PDF)
254The blood–brain barrier efflux transporters as a detoxifying system for the brain15.495Citations (PDF)
255Effects of Arginine-Vasopressin Fragment 4–9 on Rodent Cholinergic Systems2.322Citations (PDF)
256Differences in the hepatobiliary transport of two quinolone antibiotics, grepafloxacin and lomefloxacin, in the rat
1999, 20, 151-158
16Citations (PDF)
257A Novel Stromal Cell-Dependent B Lymphoid Stem-Like Cell Line That Induces Immunoglobulin Gene Rearrangement
Journal of Biochemistry, 1999, 125, 602-612
1.56Citations (PDF)
258Modulation of the Tumor Disposition of Vinca Alkaloids by PSC 833 In Vitro and In Vivo3.31Citations (PDF)
259Efflux of Taurocholic Acid Across the Blood-Brain Barrier: Interaction with Cyclic Peptides3.320Citations (PDF)
260Brain-to-blood active transport of β-alanine across the blood-brain barrier
FEBS Letters, 1997, 400, 131-135
2.717Citations (PDF)
261Cell density-dependent mitogenic effect and -independent cellular handling of epidermal growth factor in primary cultured rat hepatocytes
Journal of Hepatology, 1997, 26, 353-360
4.28Citations (PDF)
262Role of efflux transport across the blood-brain barrier and blood-cerebrospinal fluid barrier on the disposition of xenobiotics in the central nervous system15.493Citations (PDF)
263Efficient Delivery of Circulating Poliovirus to the Central Nervous System Independently of Poliovirus Receptor
Virology, 1997, 229, 421-428
2.3112Citations (PDF)
264Distributed Model Analysis of 3′-Azido-3′-Deoxythymidine and 2′,3′-Dideoxyinosine Distribution in Brain Tissue and Cerebrospinal Fluid3.319Citations (PDF)
265P-Glycoprotein Mediates the Efflux of Quinidine across the Blood-Brain Barrier3.350Citations (PDF)
266Kinetic Evidence for Active Efflux Transport across the Blood-Brain Barrier of Quinolone Antibiotics3.323Citations (PDF)
267In Vivo and In Vitro Evidence for Nonrestricted Transport of 2′,7′-Bis(2-Carboxyethyl)-5(6)-Carboxyfluorescein Tetraacetoxymethyl Ester at the Blood-Brain Barrier3.310Citations (PDF)
268Kinetic Analysis of the Disposition of MRK16, an Anti-P-glycoprotein Monoclonal Antibody, in Tumors: Comparison Between in Vitro and in Vivo Disposition3.34Citations (PDF)
269Selective Brain to Blood Efflux Transport of para-Aminohippuric Acid across the Blood-Brain Barrier:In Vivo Evidence by Use of the Brain Efflux Index Method3.319Citations (PDF)
270In Vivo Evidence for Carrier-Mediated Efflux Transport of 3′-Azido-3′-Deoxythymidine and 2′,3′-Dideoxyinosine Across the Blood-Brain Barrier via a Probenecid-Sensitive Transport System3.333Citations (PDF)
271Carrier-Mediated Hepatic Uptake of Quinolone Antibiotics in the Rat3.319Citations (PDF)
272Title is missing!
Pharmaceutical Research, 1996, 13, 1065-1068
3.715Citations (PDF)
273Title is missing!
Pharmaceutical Research, 1996, 13, 523-527
3.721Citations (PDF)
274Sodium and Chloride Ion‐Dependent Transport of β‐Alanine Across the Blood‐Brain Barrier
Journal of Neurochemistry, 1996, 67, 330-335
3.836Citations (PDF)
275Title is missing!
Pharmaceutical Research, 1995, 12, 12-17
3.720Citations (PDF)
276Title is missing!
Pharmaceutical Research, 1995, 12, 1737-1740
3.79Citations (PDF)
277Na+- and Cl−-Dependent transport of taurine at the blood-brain barrier
Biochemical Pharmacology, 1995, 50, 1783-1793
5.189Citations (PDF)
278Drug delivery to the brain utilizing blood-brain barrier transport systems11.020Citations (PDF)
279Title is missing!
Pharmaceutical Research, 1994, 11, 975-978
3.743Citations (PDF)
280Title is missing!
Pharmaceutical Research, 1994, 11, 30-37
3.7145Citations (PDF)
281Title is missing!
Pharmaceutical Research, 1994, 11, 305-311
3.7200Citations (PDF)
282Title is missing!
Pharmaceutical Research, 1994, 11, 1516-1518
3.744Citations (PDF)
283Functional expression of intestinal dipeptide/β-lactam antibiotic transporter in Xenopus laevis oocytes
Biochemical Pharmacology, 1994, 48, 881-888
5.128Citations (PDF)
284Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma1.317Citations (PDF)
285Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein
Biochemical Pharmacology, 1993, 46, 1096-1099
5.1165Citations (PDF)
286Blood-Brain Barrier Transport of Ebiratide and Its Uptake by Cerebral Neuronal Cells4.00Citations (PDF)
287P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells
Life Sciences, 1992, 51, 1427-1437
4.5271Citations (PDF)
288Title is missing!
Pharmaceutical Research, 1992, 09, 529-534
3.744Citations (PDF)
289Receptor-mediated endocytosis of A14-125I-insulin by the nonfiltering perfused rat kidney2.017Citations (PDF)
290Title is missing!
Pharmaceutical Research, 1991, 08, 815-820
3.774Citations (PDF)
291Title is missing!
Pharmaceutical Research, 1991, 08, 563-569
3.733Citations (PDF)
292Receptor-recycling model of clearance and distribution of insulin in the perfused mouse liver
Diabetologia, 1991, 34, 613-621
7.544Citations (PDF)
293pH-Dependent Intestinal Transport of Monocarboxylic Acids: Carrier-Mediated and H+-Cotransport Mechanism Versus pH-Partition Hypothesis3.245Citations (PDF)
294Degradation Kinetics of (±)-4′-Ethyl-2-methyl-3-(1-pyrrolidinyl)propiophenone Hydrochloride (HY-770) and Structure–Stability Relationship among its Analogues in Aqueous Solution3.22Citations (PDF)
295Serum Protein Binding of Lomefloxacin, a New Antimicrobial Agent, and Its Related Quinolones3.216Citations (PDF)
296Age-Related Change in Tissue-to-Plasma Partition Coefficient of Cefazolin for Noneliminating Organs in the Rat3.217Citations (PDF)
297Effects of Atropine on Adrenergic Responsiveness and Reflex Vasoconstriction in Humans0.30Citations (PDF)
298Differential Binding of Testosterone and Estradiol to Isoforms of Sex Hormone-Binding Globulin: Selective Alteration of Estradiol Binding in Cirrhosis*4.037Citations (PDF)
299Differential binding of thyroxine and triiodothyronine to acidic isoforms of thyroid hormone binding globulin in human serum
Biochemistry, 1988, 27, 3624-3628
2.414Citations (PDF)
300Restricted Transport of 3'-Azido-3'-Deoxythymidine and Dideoxynucleosides Through the Blood-Brain Barrier
Journal of Infectious Diseases, 1988, 158, 630-632
3.7110Citations (PDF)
301Stereospecificity of Triiodothyronine Transport into Brain, Liver, and Salivary Gland: Role of Carrier- and Plasma Protein-Mediated Transport*
Endocrinology, 1987, 121, 1185-1191
2.527Citations (PDF)
302β-Lactam antibiotics and transport via the dipeptide carrier system across the intestinal brush-border membrane
Biochemical Pharmacology, 1987, 36, 565-567
5.149Citations (PDF)
303H+ gradient-dependent and carrier-mediated transport of cefixime, a new cephalosporin antibiotic, across brush-border membrane vesicles from rat small intestine.3.324Citations (PDF)
304Uptake of benzylpenicillin, cefpiramide and cefazolin by freshly prepared rat hepatocytes
Biochemical Pharmacology, 1986, 35, 151-158
5.158Citations (PDF)
305Theoretical consideration of drug distribution kinetics in a noneliminating organ: Comparison between a “homogeneous (well-stirred)” model and “nonhomogeneous (tube)” model0.78Citations (PDF)
306Interaction of Doxorubicin with Nuclei Isolated from Rat Liver and Kidney3.216Citations (PDF)
307Pharmacokinetic Study on the Mechanism of Tissue Distribution of Doxorubicin: Interorgan and Interspecies Variation of Tissue-To-Plasma Partition Coefficients in Rats, Rabbits, and Guinea Pigs3.279Citations (PDF)
308Physiologically Based Pharmacokinetic Model for β-Lactam Antibiotics I: Tissue Distribution and Elimanation Rates3.2150Citations (PDF)
309Carbenicillin Prodrugs: Kinetics of Intestinal Absorption Competing Degradation of the α-Esters of Carbenicillin and Prediction of Prodrug Absorbability from Quantitative Structure-Absorption Rate Relationship3.28Citations (PDF)
310Carbenicillin Prodrugs: Stability Kinetics of α-phenyl and α-indanyl Esters in Aqueous Solution3.212Citations (PDF)
311Enhanced Polarity of Sulfonamide Metformin Derivatives Increases Cellular Uptake and Apoptosis-Inducing Effects in Human Breast Cancer Cells
Molecular Pharmaceutics, 0, 23, 680-693
4.21Citations (PDF)
312PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR CEFAZOLIN IN RABBITS AND ITS PRELIMINARY EXTRAPOLATION TO MAN3.61Citations (PDF)
313A disintegrin and metalloproteinase with thrombospondin motifs 18 (ADAMTS18) cleaves fibronectin and negatively regulates its fibrillogenesis2.21Citations (PDF)
314Elucidating the roles of TM7SF3 and LHFPL6 in the putative H+/OC antiporter function in the human brain capillary endothelial cell line, hCMEC/D34.30Citations (PDF)
315Role of the arachnoid mater organic anion and cation transporters in the clearance of prostaglandin D2 and metformin from the cerebrospinal fluid in rats2.10Citations (PDF)