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175 peer-reviewed articles • 28,936 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Association between NF-E2-related factor 2 polymorphism and age-related hearing loss in the general Japanese population from the Iwaki health promotion project
Acta Oto-Laryngologica, 2025, 145, 36-42
0.91Citations (PDF)
2Dairy consumption has a partial inverse association with systolic blood pressure and hypertension in populations with high salt and low dairy diets: cross-sectional data analysis from the Iwaki Health Promotion Project
Hypertension Research, 2025, 48, 1409-1421
3.05Citations (PDF)
3Role of calpain-5 in cerebral ischemia and reperfusion injury2.04Citations (PDF)
4Emerging Role of GCN1 in Disease and Homeostasis4.410Citations (PDF)
5Dairy consumption, bone turnover biomarkers, and osteo sono assessment index in Japanese adults: A cross-sectional analysis of data from the Iwaki Health Promotion Project
Bone Reports, 2024, 21, 101770
0.71Citations (PDF)
6Association between sex hormones and erectile dysfunction in men without hypoandrogenism
Scientific Reports, 2024, 14,
3.46Citations (PDF)
7Nrf2 induction potency of plant-derived compounds determined using an antioxidant response element luciferase reporter and conventional NAD(P)H-quinone acceptor oxidoreductase 1 activity assay
BMC Research Notes, 2024, 17,
1.52Citations (PDF)
8Role of Nrf2-Mediated Oxidative Stress Response Pathway in the Regulation of Mibyou
Kagaku To Seibutsu, 2024, 62, 145-153
0.00Citations (PDF)
9Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment1.79Citations (PDF)
10Association of Plasma Lipopolysaccharide-Binding Protein Concentration with Dietary Factors, Gut Microbiota, and Health Status in the Japanese General Adult Population: A Cross-Sectional Study
Metabolites, 2023, 13, 250
3.414Citations (PDF)
11Annual stability of the plasma Aß40/42 ratio and associated factors3.83Citations (PDF)
12Role of Nrf2 in 1,2-dichloropropane-induced cell proliferation and DNA damage in the mouse liver
Toxicological Sciences, 2023, 195, 28-41
3.85Citations (PDF)
13Definition of a Dietary Pattern Expressing the Intake of Vegetables and Fruits and Its Association with Intestinal Microbiota
Nutrients, 2023, 15, 2104
4.52Citations (PDF)
14Individual health-disease phase diagrams for disease prevention based on machine learning3.78Citations (PDF)
15Does the Protective Effect of Zinc on Telomere Length Depend on the Presence of Hypertension or Type 2 Diabetes? Results from the Iwaki Health Promotion Project, Japan
Nutrients, 2023, 15, 4373
4.52Citations (PDF)
16Mitochondrial Reactive Oxygen Species, Insulin Resistance, and Nrf2-Mediated Oxidative Stress Response—Toward an Actionable Strategy for Anti-Aging
Biomolecules, 2023, 13, 1544
4.351Citations (PDF)
17Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project
Journal of Human Genetics, 2022, 67, 369-375
2.05Citations (PDF)
18Inducible Systemic Gcn1 Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage4.45Citations (PDF)
19Impact of salivary and pancreatic amylase gene copy numbers on diabetes, obesity, and functional profiles of microbiome in Northern Japanese population
Scientific Reports, 2022, 12,
3.412Citations (PDF)
20Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice4.415Citations (PDF)
21Association between Serum Concentration of Carotenoid and Visceral Fat
Nutrients, 2021, 13, 912
4.510Citations (PDF)
22Characterization of mitochondrial calpain-53.619Citations (PDF)
23Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice
Toxicology, 2021, 456, 152785
4.726Citations (PDF)
24Health improvement framework for actionable treatment planning using a surrogate Bayesian model13.713Citations (PDF)
25Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study
Metabolites, 2021, 11, 314
3.45Citations (PDF)
26Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction2.529Citations (PDF)
27Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis1.36Citations (PDF)
28Age-Related Cognitive Decline and Prevalence of Mild Cognitive Impairment in the Iwaki Health Promotion Project
Journal of Alzheimer's Disease, 2021, 84, 1233-1245
2.613Citations (PDF)
29Telomere Length and Arterial Stiffness Reflected by Brachial–Ankle Pulse Wave Velocity: A Population-Based Cross-Sectional Study2.45Citations (PDF)
30Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan2.220Citations (PDF)
31Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging
PLoS ONE, 2020, 15, e0236834
2.313Citations (PDF)
32JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4–DR5 axis
FEBS Open Bio, 2020, 10, 2771-2779
2.29Citations (PDF)
33Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness
Nutrients, 2020, 12, 2310
4.527Citations (PDF)
34Blockade of PAR‐1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin‐Overexpressing Hypertensive Mice4.020Citations (PDF)
35Regulation of Nrf2 by Mitochondrial Reactive Oxygen Species in Physiology and Pathology
Biomolecules, 2020, 10, 320
4.3484Citations (PDF)
36Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice
PLoS Genetics, 2020, 16, e1008693
3.235Citations (PDF)
37Concomitant Nrf2- and ATF4-Activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes4.435Citations (PDF)
38Increase of Tumor Infiltrating γδ T-cells in Pancreatic Ductal Adenocarcinoma Through Remodeling of the Extracellular Matrix by a Hyaluronan Synthesis Suppressor, 4-Methylumbelliferone
Pancreas, 2019, 48, 292-298
0.911Citations (PDF)
39Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles7.932Citations (PDF)
40Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control1.493Citations (PDF)
41Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease6.944Citations (PDF)
42Characterization of CuCl quantum dots grown in NaCl single crystals via optical measurements, X-ray diffraction, and transmission electron microscopy
Journal of Crystal Growth, 2018, 490, 84-88
1.97Citations (PDF)
43Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease2.463Citations (PDF)
44Aging and APOE‐ε4 are determinative factors of plasma Aβ42 levels3.825Citations (PDF)
45C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape3.493Citations (PDF)
46Effects of deficiency of Kelch‐like ECH‐associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis
FASEB Journal, 2017, 31, 4011-4022
0.625Citations (PDF)
47Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2
FEBS Journal, 2017, 284, 4115-4127
5.47Citations (PDF)
48Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K
Glycobiology, 2017, 27, 1089-1098
2.225Citations (PDF)
49The role of NUB1 in α-synuclein degradation in Lewy body disease model mice2.13Citations (PDF)
50p62 Deficiency Enhances α‐Synuclein Pathology in Mice
Brain Pathology, 2015, 25, 552-564
5.042Citations (PDF)
51Carnosic acid attenuates apoptosis induced by amyloid-β 1–42 or 1–43 in SH-SY5Y human neuroblastoma cells
Neuroscience Research, 2015, 94, 1-9
2.151Citations (PDF)
52Role of the Keap1/Nrf2 pathway in neurodegenerative diseases
Pathology International, 2015, 65, 210-219
1.8118Citations (PDF)
53Role of Nrf2 in the pathogenesis of atherosclerosis3.7145Citations (PDF)
54Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease2.187Citations (PDF)
55Non-coding RNA derived from the region adjacent to the human HO-1 E2 enhancer selectively regulates HO-1 gene induction by modulating Pol II binding
Nucleic Acids Research, 2014, 42, 13599-13614
15.557Citations (PDF)
56Nrf2- and ATF4-Dependent Upregulation of xCT Modulates the Sensitivity of T24 Bladder Carcinoma Cells to Proteasome Inhibition
Molecular and Cellular Biology, 2014, 34, 3421-3434
2.5194Citations (PDF)
57Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain5.054Citations (PDF)
58Carbocisteine Reduces Virus-Induced Pulmonary Inflammation in Mice Exposed to Cigarette Smoke3.822Citations (PDF)
59Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells
Neuroscience Research, 2014, 79, 83-93
2.151Citations (PDF)
60Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene
Journal of Biological Chemistry, 2013, 288, 20658-20667
2.256Citations (PDF)
61Carnosic acid suppresses the production of amyloid-β 1–42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells
Neuroscience Research, 2013, 75, 94-102
2.150Citations (PDF)
62Keap1 Is Localized in Neuronal and Glial Cytoplasmic Inclusions in Various Neurodegenerative Diseases1.872Citations (PDF)
63Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter
Nucleic Acids Research, 2013, 41, 5223-5234
15.569Citations (PDF)
64Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis
Journal of Gastroenterology, 2012, 47, 924-935
4.174Citations (PDF)
65Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation3.773Citations (PDF)
66Methylation of the KEAP1 gene promoter region in human colorectal cancer
BMC Cancer, 2012, 12,
2.9170Citations (PDF)
67Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes
Journal of Biochemistry, 2011, 150, 209-217
1.659Citations (PDF)
68Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages2.8205Citations (PDF)
69Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation
Neuroscience Research, 2011, 69, 291-298
2.122Citations (PDF)
70Synphilin-1-Binding Protein NUB1 is Colocalized With Nonfibrillar, Proteinase K-Resistant α-Synuclein in Presynapses in Lewy Body Disease1.815Citations (PDF)
71Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers
Genes To Cells, 2011, 16, 406-415
1.421Citations (PDF)
72Role of Nrf2 in Host Defense against Influenza Virus in Cigarette Smoke-Exposed Mice
Journal of Virology, 2011, 85, 4679-4690
3.692Citations (PDF)
73The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response
Biochemical Journal, 2011, 436, 387-397
3.828Citations (PDF)
74Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice
Acta Neuropathologica, 2010, 120, 145-154
9.2104Citations (PDF)
75Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance4.2158Citations (PDF)
76Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene
BMC Cancer, 2010, 10,
2.962Citations (PDF)
77Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response6.043Citations (PDF)
78p122 Protein Enhances Intracellular Calcium Increase to Acetylcholine6.011Citations (PDF)
79Increased Susceptibility of Nrf2-Null Mice to 1-Bromopropane–Induced Hepatotoxicity
Toxicological Sciences, 2010, 115, 596-606
3.852Citations (PDF)
80Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice
Journal of Biochemistry, 2010, 147, 353-360
1.622Citations (PDF)
81Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells
Journal of Biochemistry, 2010, 147, 73-81
1.691Citations (PDF)
82Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview6.3487Citations (PDF)
83Suppression of SLC11A2 Expression Is Essential to Maintain Duodenal Integrity During Dietary Iron Overload
American Journal of Pathology, 2010, 177, 677-685
3.421Citations (PDF)
84Relationship between Radiosensitivity and Nrf2 Target Gene Expression in Human Hematopoietic Stem Cells
Radiation Research, 2010, 174, 177-184
2.137Citations (PDF)
85Role of Nrf2/antioxidant response element in mammary carcinogenesis
FASEB Journal, 2010, 24,
0.60Citations (PDF)
86Heavy Ion Beam Irradiation Regulates the mRNA Expression in Megakaryocytopoiesis from Human Hematopoietic Stem/Progenitor Cells1.812Citations (PDF)
87Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents3.2170Citations (PDF)
88Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice2.157Citations (PDF)
89Essential role of Nrf2 in keratinocyte protection from UVA by quercetin2.178Citations (PDF)
90Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice
Toxicology Letters, 2009, 185, 180-186
0.666Citations (PDF)
91Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2‐deficient mice
Genes To Cells, 2008, 13, 1159-1170
1.4191Citations (PDF)
92Attenuation of UVB-Induced Sunburn Reaction and Oxidative DNA Damage with no Alterations in UVB-Induced Skin Carcinogenesis in Nrf2 Gene-Deficient Mice2.380Citations (PDF)
93Carnosic acid, a catechol‐type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S‐alkylation of targeted cysteines on Keap1
Journal of Neurochemistry, 2008, 104, 1116-1131
3.8367Citations (PDF)
94Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein3.2123Citations (PDF)
95Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners
Neuroscience Letters, 2008, 434, 260-265
1.9119Citations (PDF)
96Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements2.896Citations (PDF)
97Keap1 Regulates the Constitutive Expression of GST A1 during Differentiation of Caco-2 Cells
Biochemistry, 2008, 47, 6169-6177
2.418Citations (PDF)
98A Possible Role of Nrf2 in Prevention of Renal Oxidative Damage by Ferric Nitrilotriacetate
Toxicologic Pathology, 2008, 36, 353-361
1.326Citations (PDF)
99Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts
Free Radical Research, 2008, 42, 297-304
2.638Citations (PDF)
100Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis
Carcinogenesis, 2007, 28, 2398-2403
2.874Citations (PDF)
101Double-stranded RNA induces galectin-9 in vascular endothelial cells: involvement of TLR3, PI3K, and IRF3 pathway
Glycobiology, 2007, 17, 12C-15C
2.241Citations (PDF)
102Molecular Basis Distinguishing the DNA Binding Profile of Nrf2-Maf Heterodimer from That of Maf Homodimer
Journal of Biological Chemistry, 2007, 282, 33681-33690
2.299Citations (PDF)
103Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers3.381Citations (PDF)
104Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes
Biochemical Journal, 2007, 404, 459-466
3.8103Citations (PDF)
105Subcellular localization and cytoplasmic complex status of endogenous Keap1
Genes To Cells, 2007, 12, 1163-1178
1.4130Citations (PDF)
106Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f]quinoline
Cancer Science, 2007, 98, 19-24
3.973Citations (PDF)
107Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species3.7163Citations (PDF)
108Dimerisation of adaptor protein Keap1 is required to correctly position Nrf2 for ubiquitylation upon the Cul3‐Rbx1 holoenzyme: the ‘fixed‐ends’ model
FASEB Journal, 2007, 21,
0.60Citations (PDF)
109Ebselen, a Seleno-organic Antioxidant, as an Electrophile
Chemical Research in Toxicology, 2006, 19, 1196-1204
3.7146Citations (PDF)
110Tissue Prx I in the protection against Fe-NTA and the reduction of nitroxyl radicals2.124Citations (PDF)
111Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress3.758Citations (PDF)
112A Crucial Role of Nrf2 in In Vivo Defense against Oxidative Damage by an Environmental Pollutant, Pentachlorophenol
Toxicological Sciences, 2006, 90, 111-119
3.873Citations (PDF)
113Keap1 Recruits Neh2 through Binding to ETGE and DLG Motifs: Characterization of the Two-Site Molecular Recognition Model
Molecular and Cellular Biology, 2006, 26, 2887-2900
2.5701Citations (PDF)
114BRG1 Interacts with Nrf2 To Selectively Mediate HO-1 Induction in Response to Oxidative Stress
Molecular and Cellular Biology, 2006, 26, 7942-7952
2.5205Citations (PDF)
115Dimerization of Substrate Adaptors Can Facilitate Cullin-mediated Ubiquitylation of Proteins by a “Tethering” Mechanism
Journal of Biological Chemistry, 2006, 281, 24756-24768
2.2456Citations (PDF)
116Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema
Genes To Cells, 2005, 10, 1113-1125
1.4316Citations (PDF)
117Ultraviolet A Irradiation Induces NF-E2-Related Factor 2 Activation in Dermal Fibroblasts: Protective Role in UVA-Induced Apoptosis2.3154Citations (PDF)
118Regulatory Role of the COX-2 Pathway in the Nrf2-Mediated Anti-Inflammatory Response1.410Citations (PDF)
119Selective Induction of the Tumor Marker Glutathione S-Transferase P1 by Proteasome Inhibitors*
Journal of Biological Chemistry, 2005, 280, 25267-25276
2.229Citations (PDF)
120Differential Responses of the Nrf2-Keap1 System to Laminar and Oscillatory Shear Stresses in Endothelial Cells
Journal of Biological Chemistry, 2005, 280, 27244-27250
2.2212Citations (PDF)
121Role of 15-DeoxyΔ12,14 Prostaglandin J 2 and Nrf2 Pathways in Protection against Acute Lung Injury9.0115Citations (PDF)
122Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species-induced cell injury
FEBS Letters, 2005, 579, 3029-3036
2.7364Citations (PDF)
123Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome2.8202Citations (PDF)
124Protective Roles of Nrf2 in Disease including Oral Disease
Journal of Oral Biosciences, 2005, 47, 126-134
2.00Citations (PDF)
125Protective Roles of Nrf2 in Disease including Oral Disease
Journal of Oral Biosciences, 2005, 47, 126-134
2.00Citations (PDF)
126Transcription Factor Nrf2 Is Essential for Induction of NAD(P)H:Quinone Oxidoreductase 1, Glutathione S-Transferases, and Glutamate Cysteine Ligase by Broccoli Seeds and Isothiocyanates
Journal of Nutrition, 2004, 134, 3499S-3506S
2.9193Citations (PDF)
127Transcription Factor Nrf2 Regulates Inflammation by Mediating the Effect of 15-Deoxy-Δ 12,14 -Prostaglandin J 22.5403Citations (PDF)
128Redox-regulated Turnover of Nrf2 Is Determined by at Least Two Separate Protein Domains, the Redox-sensitive Neh2 Degron and the Redox-insensitive Neh6 Degron
Journal of Biological Chemistry, 2004, 279, 31556-31567
2.2368Citations (PDF)
129Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages
Circulation Research, 2004, 94, 609-616
13.2405Citations (PDF)
130Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ
Genes To Cells, 2004, 9, 641-651
1.459Citations (PDF)
131Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr
Kidney International, 2004, 65, 1703-1713
5.332Citations (PDF)
132Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles3.7826Citations (PDF)
133Activation of hepatic Nrf2in vivo by acetaminophen in CD-1 mice
Hepatology, 2004, 39, 1267-1276
10.1199Citations (PDF)
134EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice3.782Citations (PDF)
135Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles
Genes To Cells, 2003, 8, 379-391
1.4753Citations (PDF)
136Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
Nature Genetics, 2003, 35, 238-245
25.2855Citations (PDF)
137Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts2.1255Citations (PDF)
138Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts2.194Citations (PDF)
139Expression of the Aflatoxin B1-8,9-Epoxide-Metabolizing Murine Glutathione S-Transferase A3 Subunit Is Regulated by the Nrf2 Transcription Factor through an Antioxidant Response Element
Molecular Pharmacology, 2003, 64, 1018-1028
2.676Citations (PDF)
140Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice
Carcinogenesis, 2003, 24, 461-467
2.8182Citations (PDF)
141Modulation of Gene Expression by Cancer Chemopreventive Dithiolethiones through the Keap1-Nrf2 Pathway
Journal of Biological Chemistry, 2003, 278, 8135-8145
2.2633Citations (PDF)
142Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression
Journal of Biological Chemistry, 2003, 278, 21592-21600
2.21,074Citations (PDF)
143Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence
Biochemical Journal, 2003, 374, 337-348
3.8467Citations (PDF)
144A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway
Journal of Biological Chemistry, 2002, 277, 3456-3463
2.2257Citations (PDF)
145Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants7.51,854Citations (PDF)
146Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
Biochemical Journal, 2002, 365, 405-416
3.8430Citations (PDF)
147Electrophile Response Element-mediated Induction of the Cystine/Glutamate Exchange Transporter Gene Expression
Journal of Biological Chemistry, 2002, 277, 44765-44771
2.2510Citations (PDF)
148Nrf2 transactivator-independent GSTP1-1 expression in `GSTP1-1 positive' single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells
Carcinogenesis, 2002, 23, 457-462
2.822Citations (PDF)
149Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter
Molecular and Cellular Biology, 2002, 22, 2883-2892
2.5581Citations (PDF)
150Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
Genes To Cells, 2002, 7, 807-820
1.4325Citations (PDF)
151High Sensitivity of Nrf2 Knockout Mice to Acetaminophen Hepatotoxicity Associated with Decreased Expression of ARE-Regulated Drug Metabolizing Enzymes and Antioxidant Genes
Toxicological Sciences, 2001, 59, 169-177
3.8688Citations (PDF)
152Role of Transcription Factor Nrf2 in the Induction of Hepatic Phase 2 and Antioxidative Enzymes in vivo by the Cancer Chemoprotective Agent, 3H-1, 2-Dithiole-3-thione
Molecular Medicine, 2001, 7, 135-145
5.6331Citations (PDF)
153Nrf2-deficient female mice develop lupus-like autoimmune nephritis11See Editorial by Byrd and Thomas, p. 1606.
Kidney International, 2001, 60, 1343-1353
5.3340Citations (PDF)
154Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
Genes To Cells, 2001, 6, 857-868
1.4477Citations (PDF)
155Accelerated DNA Adduct Formation in the Lung of the Nrf2 Knockout Mouse Exposed to Diesel Exhaust3.2289Citations (PDF)
156Role of phase 2 enzyme induction in chemoprotection by dithiolethiones1.8224Citations (PDF)
157Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice7.51,084Citations (PDF)
158Hemin-induced Activation of the Thioredoxin Gene by Nrf2
Journal of Biological Chemistry, 2001, 276, 18399-18406
2.2292Citations (PDF)
159Induction of murine intestinal and hepatic peroxiredoxin MSP23 by dietary butylated hydroxyanisole
Carcinogenesis, 2000, 21, 1013-1016
2.826Citations (PDF)
160Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages
Journal of Biological Chemistry, 2000, 275, 16023-16029
2.21,390Citations (PDF)
161Regulatory mechanisms of cellular response to oxidative stress
Free Radical Research, 1999, 31, 319-324
2.6339Citations (PDF)
162Oxidative stress-inducible proteins in macrophages
Free Radical Research, 1999, 31, 351-355
2.6112Citations (PDF)
163Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
Genes and Development, 1999, 13, 76-86
4.63,366Citations (PDF)
164An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements2.13,821Citations (PDF)
165Activity and Expression of Murine Small Maf Family Protein MafK
Journal of Biological Chemistry, 1995, 270, 7615-7624
2.297Citations (PDF)
166Cloning and Characterization of a Novel Erythroid Cell-Derived CNC Family Transcription Factor Heterodimerizing with the Small Maf Family Proteins
Molecular and Cellular Biology, 1995, 15, 4184-4193
2.5426Citations (PDF)
167Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
Nature, 1994, 367, 568-572
38.0446Citations (PDF)
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