| 1 | Functional validation of a novel STAT3 ‘variant of unknown significance’ identifies a new case of STAT3 GOF syndrome and reveals broad immune cell defects. | 2.3 | 4 | Citations (PDF) |
| 2 | The 2024 update of IUIS phenotypic classification of human inborn errors of immunity 2025, 1, | | 149 | Citations (PDF) |
| 3 | Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee 2025, 1, | | 294 | Citations (PDF) |
| 4 | Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease | 8.7 | 14 | Citations (PDF) |
| 5 | SPI-ing on human B-cell developmentBlood, 2025, 145, 2535-2536 | 3.6 | 1 | Citations (PDF) |
| 6 | Human LY9 governs CD4
+
T cell IFN-γ immunity to
Mycobacterium tuberculosis | 8.9 | 14 | Citations (PDF) |
| 7 | The trajectory of human B‐cell function, immune deficiency, and allergy revealed by inborn errors of immunity | 5.8 | 2 | Citations (PDF) |
| 8 | A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome | 1.7 | 6 | Citations (PDF) |
| 9 | Role of IL-27 in Epstein–Barr virus infection revealed by IL-27RA deficiency | 30.6 | 48 | Citations (PDF) |
| 10 | Helper T cell immunity in humans with inherited CD4 deficiency | 5.9 | 14 | Citations (PDF) |
| 11 | Development of EBV Related Diffuse Large B-cell Lymphoma in Deficiency of Adenosine Deaminase 2 with Uncontrolled EBV Infection | 1.7 | 10 | Citations (PDF) |
| 12 | A Novel Case of IFNAR1 Deficiency Identified a Common Canonical Splice Site Variant in DOCK8 in Western Polynesia: The Importance of Validating Variants of Unknown Significance in Under-Represented Ancestries | 1.7 | 4 | Citations (PDF) |
| 13 | Tuberculosis in otherwise healthy adults with inherited TNF deficiency | 30.6 | 53 | Citations (PDF) |
| 14 | Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination | 5.9 | 46 | Citations (PDF) |
| 15 | The ups and downs of STAT3 function: too much, too little and human immune dysregulation | 2.3 | 43 | Citations (PDF) |
| 16 | Cytokine-mediated STAT-dependent pathways underpinning human B-cell differentiation and function | 3.7 | 17 | Citations (PDF) |
| 17 | Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria | 8.9 | 74 | Citations (PDF) |
| 18 | Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2 | 5.9 | 33 | Citations (PDF) |
| 19 | Inborn errors of immunity: the Goldilocks effect—susceptibility to disease due to a little too much or a little too little | 2.3 | 2 | Citations (PDF) |
| 20 | Inborn errors of human B cell development, differentiation, and function | 5.9 | 54 | Citations (PDF) |
| 21 | Do multiple subsets of CD11c+ B cells exist? You (T)-Bet! | 4.4 | 11 | Citations (PDF) |
| 22 | Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency | 30.6 | 112 | Citations (PDF) |
| 23 | Human genetic and immunological determinants of critical COVID-19 pneumonia | 30.6 | 350 | Citations (PDF) |
| 24 | Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation | 3.7 | 54 | Citations (PDF) |
| 25 | Severe COVID‐19 represents an undiagnosed primary immunodeficiency in a high proportion of infected individuals | 2.0 | 13 | Citations (PDF) |
| 26 | A loss-of-function
IFNAR1
allele in Polynesia underlies severe viral diseases in homozygotes | 5.9 | 64 | Citations (PDF) |
| 27 | STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis | 4.4 | 32 | Citations (PDF) |
| 28 | A Novel Targeted Amplicon Next-Generation Sequencing Gene Panel for the Diagnosis of Common Variable Immunodeficiency Has a High Diagnostic Yield | 1.9 | 12 | Citations (PDF) |
| 29 | The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies | 5.2 | 187 | Citations (PDF) |
| 30 | Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee | 1.7 | 1,063 | Citations (PDF) |
| 31 | Human T-bet governs the generation of a distinct subset of CD11c
high
CD21
low
B cells | 8.9 | 82 | Citations (PDF) |
| 32 | Coronavirus disease 2019 in patients with inborn errors of immunity: An international study | 4.4 | 324 | Citations (PDF) |
| 33 | Molecular requirements for human lymphopoiesis as defined by inborn errors of immunity | 2.7 | 4 | Citations (PDF) |
| 34 | Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency | 6.6 | 36 | Citations (PDF) |
| 35 | The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee | 1.7 | 189 | Citations (PDF) |
| 36 | Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency | 1.7 | 39 | Citations (PDF) |
| 37 | CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph | 10.8 | 45 | Citations (PDF) |
| 38 | Hematopoietic Stem Cell Transplantation Cures Chronic Aichi Virus Infection in a Patient with X-linked Agammaglobulinemia | 1.7 | 10 | Citations (PDF) |
| 39 | Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance | 5.9 | 60 | Citations (PDF) |
| 40 | High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency | 5.9 | 38 | Citations (PDF) |
| 41 | Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications | 2.3 | 12 | Citations (PDF) |
| 42 | Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child | 22.6 | 111 | Citations (PDF) |
| 43 | Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthyCell, 2021, 184, 3812-3828.e30 | 23.4 | 95 | Citations (PDF) |
| 44 | Tissue‐resident regulatory T cells accumulate at human barrier lymphoid organs | 2.0 | 13 | Citations (PDF) |
| 45 | Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths | 8.9 | 565 | Citations (PDF) |
| 46 | X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 | 8.9 | 391 | Citations (PDF) |
| 47 | Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents | 6.6 | 37 | Citations (PDF) |
| 48 | Mechanisms underlying host defense and disease pathology in response to severe acute respiratory syndrome (SARS)-CoV2 infection: insights from inborn errors of immunity | 1.5 | 22 | Citations (PDF) |
| 49 | Coronavirus disease 2019 in patients with inborn errors of immunity: lessons learned | 1.4 | 51 | Citations (PDF) |
| 50 | Molecular regulation and dysregulation of T follicular helper cells – learning from inborn errors of immunity | 3.7 | 13 | Citations (PDF) |
| 51 | The expansion of human T-bet
high
CD21
low
B cells is T cell dependent | 8.9 | 151 | Citations (PDF) |
| 52 | Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency | 1.7 | 46 | Citations (PDF) |
| 53 | Hyper-IgE Syndrome due to an Elusive Novel Intronic Homozygous Variant in DOCK8 | 1.7 | 10 | Citations (PDF) |
| 54 | Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes | 8.9 | 27 | Citations (PDF) |
| 55 | Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production | 5.9 | 48 | Citations (PDF) |
| 56 | Regulation of the germinal center and humoral immunity by interleukin-21 | 5.9 | 104 | Citations (PDF) |
| 57 | Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome | 5.9 | 99 | Citations (PDF) |
| 58 | Autoantibodies against type I IFNs in patients with life-threatening COVID-19 | 26.1 | 2,466 | Citations (PDF) |
| 59 | Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against MycobacteriaCell, 2020, 183, 1826-1847.e31 | 23.4 | 135 | Citations (PDF) |
| 60 | Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome | 1.7 | 77 | Citations (PDF) |
| 61 | The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery | 1.7 | 7 | Citations (PDF) |
| 62 | Everolimus-Induced Remission of Classic Kaposi’s Sarcoma Secondary to Cryptic Splicing Mediated CTLA4 Haploinsufficiency | 1.7 | 7 | Citations (PDF) |
| 63 | Genetic susceptibility to EBV infection: insights from inborn errors of immunity | 1.8 | 57 | Citations (PDF) |
| 64 | Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiencyBlood, 2020, 136, 2638-2655 | 3.6 | 99 | Citations (PDF) |
| 65 | Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee | 1.7 | 1,015 | Citations (PDF) |
| 66 | Systemic Inflammation and Myelofibrosis in a Patient with
Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys
Mutation | 1.7 | 44 | Citations (PDF) |
| 67 | Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infectionBlood, 2020, 135, 644-655 | 3.6 | 117 | Citations (PDF) |
| 68 | Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification | 1.7 | 628 | Citations (PDF) |
| 69 | Human inborn errors of immunity to herpes viruses | 3.7 | 85 | Citations (PDF) |
| 70 | Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity | 4.4 | 89 | Citations (PDF) |
| 71 | A deep intronic splice mutation of
STAT3
underlies hyper IgE syndrome by negative dominance | 5.2 | 27 | Citations (PDF) |
| 72 | Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity | 3.3 | 38 | Citations (PDF) |
| 73 | An essential role for the Zn2+ transporter ZIP7 in B cell development | 14.1 | 129 | Citations (PDF) |
| 74 | The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome | 4.4 | 26 | Citations (PDF) |
| 75 | B cell–intrinsic requirement for STK4 in humoral immunity in mice and human subjects | 4.4 | 23 | Citations (PDF) |
| 76 | Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction | 1.7 | 44 | Citations (PDF) |
| 77 | Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells | 4.4 | 64 | Citations (PDF) |
| 78 | Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD—the Goldilocks’ Effect | 1.7 | 40 | Citations (PDF) |
| 79 | Human CD8+ T cell cross-reactivity across influenza A, B and C viruses | 14.1 | 240 | Citations (PDF) |
| 80 | Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP | 2.0 | 50 | Citations (PDF) |
| 81 | Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β | 8.9 | 54 | Citations (PDF) |
| 82 | Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity | 14.1 | 73 | Citations (PDF) |
| 83 | What can primary immunodeficiencies teach us about Th9 cell differentiation and function? | 2.0 | 6 | Citations (PDF) |
| 84 | Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype | 1.7 | 35 | Citations (PDF) |
| 85 | Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients | 3.7 | 31 | Citations (PDF) |
| 86 | STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles | 2.7 | 37 | Citations (PDF) |
| 87 | Combined Immunodeficiency with Ring Chromosome 21 | 1.7 | 2 | Citations (PDF) |
| 88 | Circulating T
FH
cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity | 8.7 | 240 | Citations (PDF) |
| 89 | Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency | 1.7 | 3 | Citations (PDF) |
| 90 | Human plasma C3 is essential for the development of memory B, but not T, lymphocytes | 4.4 | 30 | Citations (PDF) |
| 91 | Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23 | 8.9 | 193 | Citations (PDF) |
| 92 | Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common
TYK2
missense variant | 8.9 | 206 | Citations (PDF) |
| 93 | Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia | 1.7 | 27 | Citations (PDF) |
| 94 | Germline-activating mutations in
PIK3CD
compromise B cell development and function | 5.9 | 105 | Citations (PDF) |
| 95 | Mutations affecting the actin regulator WD repeat–containing protein 1 lead to aberrant lymphoid immunity | 4.4 | 71 | Citations (PDF) |
| 96 | Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency | 14.1 | 117 | Citations (PDF) |
| 97 | Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes | 10.8 | 120 | Citations (PDF) |
| 98 | A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity | 8.9 | 167 | Citations (PDF) |
| 99 | Human immunity against EBV—lessons from the clinic | 5.9 | 165 | Citations (PDF) |
| 100 | Memory B cells: total recall | 3.7 | 61 | Citations (PDF) |
| 101 | Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency | 5.9 | 158 | Citations (PDF) |
| 102 | Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation | 10.8 | 49 | Citations (PDF) |
| 103 | Cytokine-Mediated Regulation of Human Lymphocyte Development and Function: Insights from Primary Immunodeficiencies | 0.8 | 29 | Citations (PDF) |
| 104 | Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency | 4.4 | 34 | Citations (PDF) |
| 105 | Low IgE Is Insufficiently Sensitive to Guide Genetic Testing of STAT3 Gain-of-Function Mutations | 0.6 | 4 | Citations (PDF) |
| 106 | Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells | 4.4 | 94 | Citations (PDF) |
| 107 | CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity | 16.6 | 259 | Citations (PDF) |
| 108 | International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity | 1.7 | 812 | Citations (PDF) |
| 109 | The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies | 1.7 | 529 | Citations (PDF) |
| 110 | Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency | 6.6 | 145 | Citations (PDF) |
| 111 | Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets | 5.9 | 94 | Citations (PDF) |
| 112 | Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome | 4.4 | 23 | Citations (PDF) |
| 113 | Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement | 2.0 | 30 | Citations (PDF) |
| 114 | Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases | 2.0 | 48 | Citations (PDF) |
| 115 | Dual T cell– and B cell–intrinsic deficiency in humans with biallelic
RLTPR
mutations | 5.9 | 140 | Citations (PDF) |
| 116 | B-cell–specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome | 4.4 | 31 | Citations (PDF) |
| 117 | The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance | 16.6 | 72 | Citations (PDF) |
| 118 | AD Hyper-IgE Syndrome Due to a Novel Loss-of-Function Mutation in STAT3: a Diagnostic Pursuit Won by Clinical Acuity | 1.7 | 5 | Citations (PDF) |
| 119 | Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs | 2.9 | 91 | Citations (PDF) |
| 120 | Thucydides and longer-lived plasma cellsBlood, 2015, 125, 1684-1685 | 3.6 | 1 | Citations (PDF) |
| 121 | Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies | 4.4 | 211 | Citations (PDF) |
| 122 | Impairment of immunity to
Candida
and
Mycobacterium
in humans with bi-allelic
RORC
mutations | 26.1 | 417 | Citations (PDF) |
| 123 | FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production | 16.6 | 93 | Citations (PDF) |
| 124 | Advances in IL-21 biology — enhancing our understanding of human disease | 3.7 | 65 | Citations (PDF) |
| 125 | T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses | 16.6 | 188 | Citations (PDF) |
| 126 | SnapShot: Interactions between B Cells and T CellsCell, 2015, 162, 926-926.e1 | 23.4 | 31 | Citations (PDF) |
| 127 | Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome | 5.9 | 355 | Citations (PDF) |
| 128 | STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation | 5.2 | 83 | Citations (PDF) |
| 129 | Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage | 3.3 | 219 | Citations (PDF) |
| 130 | Human T follicular helper cells in primary immunodeficiencies | 1.4 | 16 | Citations (PDF) |
| 131 | Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts | 0.5 | 9 | Citations (PDF) |
| 132 | STAT3 is a central regulator of lymphocyte differentiation and function | 3.7 | 90 | Citations (PDF) |
| 133 | XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP | 1.7 | 121 | Citations (PDF) |
| 134 | Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance | 4.4 | 35 | Citations (PDF) |
| 135 | The right “Job” for STAT3 mutant mice!Blood, 2014, 123, 2907-2909 | 3.6 | 1 | Citations (PDF) |
| 136 | Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function | 4.4 | 69 | Citations (PDF) |
| 137 | IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablastsBlood, 2013, 122, 3940-3950 | 3.6 | 152 | Citations (PDF) |
| 138 | Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure | 16.6 | 657 | Citations (PDF) |
| 139 | The good, the bad and the ugly — TFH cells in human health and disease | 32.2 | 518 | Citations (PDF) |
| 140 | Transitional B cell subsets in human bone marrow | 2.3 | 34 | Citations (PDF) |
| 141 | Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood | 5.9 | 144 | Citations (PDF) |
| 142 | Signal Transducer and Activator of Transcription 3 Limits Epstein-Barr Virus Lytic Activation in B Lymphocytes | 2.4 | 54 | Citations (PDF) |
| 143 | Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells | 5.9 | 184 | Citations (PDF) |
| 144 | To B1 or not to B1: that really is still the question!Blood, 2013, 121, 5109-5110 | 3.6 | 60 | Citations (PDF) |
| 145 | DOCK8 is critical for the survival and function of NKT cellsBlood, 2013, 122, 2052-2061 | 3.6 | 76 | Citations (PDF) |
| 146 | Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency | 14.1 | 685 | Citations (PDF) |
| 147 | Functional STAT3 deficiency compromises the generation of human T follicular helper cellsBlood, 2012, 119, 3997-4008 | 3.6 | 294 | Citations (PDF) |
| 148 | Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndrome | 4.4 | 53 | Citations (PDF) |
| 149 | The origins, function, and regulation of T follicular helper cells | 5.9 | 521 | Citations (PDF) |
| 150 | T cell–B cell interactions in primary immunodeficiencies | 2.6 | 26 | Citations (PDF) |
| 151 | Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections | 6.6 | 156 | Citations (PDF) |
| 152 | Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP | 3.1 | 111 | Citations (PDF) |
| 153 | SLAM Family Receptors and SAP Adaptors in Immunity | 22.3 | 474 | Citations (PDF) |
| 154 | Staying alive: regulation of plasma cell survival | 5.6 | 123 | Citations (PDF) |
| 155 | Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cellsBlood, 2011, 118, 116-128 | 3.6 | 26 | Citations (PDF) |
| 156 | A Subset of Interleukin-21+ Chemokine Receptor CCR9+ T Helper Cells Target Accessory Organs of the Digestive System in Autoimmunity | 16.6 | 115 | Citations (PDF) |
| 157 | Regulation of T follicular helper cell formation and function by antigen presenting cells | 3.7 | 76 | Citations (PDF) |
| 158 | IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivoBlood, 2011, 118, 6824-6835 | 3.6 | 152 | Citations (PDF) |
| 159 | DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice | 5.9 | 202 | Citations (PDF) |
| 160 | Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses | 14.1 | 282 | Citations (PDF) |
| 161 | Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cellsBlood, 2010, 115, 519-529 | 3.6 | 135 | Citations (PDF) |
| 162 | Impaired Epstein-Barr virus–specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family–positive B-cell targetsBlood, 2010, 116, 3249-3257 | 3.6 | 105 | Citations (PDF) |
| 163 | Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus | 6.1 | 652 | Citations (PDF) |
| 164 | Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling | 16.6 | 330 | Citations (PDF) |
| 165 | Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk | 2.2 | 41 | Citations (PDF) |
| 166 | B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans | 5.9 | 394 | Citations (PDF) |
| 167 | IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells | 5.9 | 204 | Citations (PDF) |
| 168 | Primary immune deficiencies affecting lymphocyte differentiation: lessons from the spectrum of resulting infections | 2.0 | 22 | Citations (PDF) |
| 169 | Invariant natural killer (iNK) T cell deficiency in patients with common variable immunodeficiency | 2.3 | 31 | Citations (PDF) |
| 170 | Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH) cell lineage is induced by IL‐12 | 2.0 | 335 | Citations (PDF) |
| 171 | Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production | 14.1 | 250 | Citations (PDF) |
| 172 | T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses | 22.3 | 594 | Citations (PDF) |
| 173 | STAT3 is required for IL-21–induced secretion of IgE from human naive B cellsBlood, 2008, 112, 1784-1793 | 3.6 | 130 | Citations (PDF) |
| 174 | Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM+IgD+CD27+ B cells harbor the virus in X-linked lymphoproliferative disease patientsBlood, 2008, 112, 672-679 | 3.6 | 39 | Citations (PDF) |
| 175 | Decreased expression of Krüppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses | 5.2 | 125 | Citations (PDF) |
| 176 | An important role for B-cell activation factor and B cells in the pathogenesis of Sjögren's syndrome | 2.4 | 54 | Citations (PDF) |
| 177 | Regulation of Cellular and Humoral Immune Responses by the SLAM and SAP Families of Molecules | 22.3 | 241 | Citations (PDF) |
| 178 | Immune cell transcriptome datasets reveal novel leukocyte subset–specific genes and genes associated with allergic processes | 4.4 | 47 | Citations (PDF) |
| 179 | BAFF, APRIL and human B cell disorders | 5.7 | 189 | Citations (PDF) |
| 180 | Persistence of naive CD45RA+ regulatory T cells in adult lifeBlood, 2006, 107, 2830-2838 | 3.6 | 262 | Citations (PDF) |
| 181 | Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP | 2.0 | 15 | Citations (PDF) |
| 182 | The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation | 5.2 | 47 | Citations (PDF) |
| 183 | Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease | 6.6 | 125 | Citations (PDF) |
| 184 | SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cellsBlood, 2005, 105, 4383-4389 | 3.6 | 179 | Citations (PDF) |
| 185 | Regulation of NKT cell development by SAP, the protein defective in XLP | 22.6 | 371 | Citations (PDF) |
| 186 | Follicular B helper T cells in antibody responses and autoimmunity | 32.2 | 573 | Citations (PDF) |
| 187 | Molecular and cellular pathogenesis of X-linked lymphoproliferative disease | 5.8 | 207 | Citations (PDF) |
| 188 | Contribution of stromal cells to the migration, function and retention of plasma cells in human spleen: potential roles of CXCL12, IL-6 and CD54 | 2.2 | 67 | Citations (PDF) |
| 189 | Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells | 6.6 | 146 | Citations (PDF) |
| 190 | Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells | 6.6 | 84 | Citations (PDF) |
| 191 | Divide and conquer: the importance of cell division in regulating B-cell responses | 3.0 | 117 | Citations (PDF) |
| 192 | Automatic generation of lymphocyte heterogeneity: Division‐dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4
+
T cells are independently regulated | 2.0 | 24 | Citations (PDF) |
| 193 | The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers | 2.8 | 123 | Citations (PDF) |
| 194 | Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrowBlood, 2004, 103, 3805-3812 | 3.6 | 129 | Citations (PDF) |
| 195 | Evidence from the generation of immunoglobulin G–secreting cells that stochastic mechanisms regulate lymphocyte differentiation | 14.1 | 210 | Citations (PDF) |
| 196 | BAFF selectively enhances the survival of plasmablasts generated from human memory B cells | 6.6 | 475 | Citations (PDF) |
| 197 | BAFF selectively enhances the survival of plasmablasts generated from human memory B cells | 6.6 | 71 | Citations (PDF) |
| 198 | CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2 | 2.2 | 85 | Citations (PDF) |
| 199 | Reduced memory B-cell populations in boys with B-cell dysfunction after bone marrow transplantation for X-linked severe combined immunodeficiency | 1.7 | 10 | Citations (PDF) |
| 200 | IgM expressed by leukemic CD5+ B cells binds mouse immunoglobulin light chain | 1.9 | 2 | Citations (PDF) |
| 201 | Protein Tyrosine Phosphatase CD148-Mediated Inhibition of T-Cell Receptor Signal Transduction Is Associated with Reduced LAT and Phospholipase Cγ1 Phosphorylation | 1.5 | 79 | Citations (PDF) |
| 202 | The CD2-subset of the Ig superfamily of cell surface molecules: receptor–ligand pairs expressed by NK cells and other immune cells | 5.7 | 131 | Citations (PDF) |
| 203 | 2B4-mediated activation of human natural killer cells | 1.9 | 101 | Citations (PDF) |
| 204 | Identification of Functional Human Splenic Memory B Cells by Expression of CD148 and CD27 | 5.9 | 425 | Citations (PDF) |
| 205 | Interleukin-10 Inhibits theIn vitroProliferation of Human Activated Leukemic CD5+B-Cells | 1.0 | 19 | Citations (PDF) |
| 206 | Human cytokines suppress apoptosis of leukaemic CD5 + B cells and preserve expression of bcl‐2 | 2.0 | 55 | Citations (PDF) |
| 207 | Cytokines and cross-linking of sIgM augment PMA-induced activation of human leukaemic CD5+B cells | 2.0 | 6 | Citations (PDF) |
| 208 | Leukaemic CD5
+
B‐cell apoptosis: co‐incidence of cell death and DNA fragmentation with reduced bcl‐2 expression | 1.7 | 14 | Citations (PDF) |
| 209 | Phorbol ester activates CD5 + leukaemic B cells via a T cell‐independent mechanism | 2.0 | 9 | Citations (PDF) |
| 210 | IRF4 haploinsufficiency in a family with Whipple’s disease | 1.0 | 65 | Citations (PDF) |
| 211 | The Next Generation of Diagnostic Tests for Primary Immunodeficiency Disorders | 2.2 | 3 | Citations (PDF) |
| 212 | Title is missing! 0 | | 1 | Citations (PDF) |
| 213 | A novel heterozygous pathogenic
AIRE
variant causing autoimmunity but not infectious susceptibility 0, 1, | | 0 | Citations (PDF) |
| 214 | Systematic functional validation of IKAROS variants from patients and laboratory-generated mutations | 3.7 | 0 | Citations (PDF) |
| 215 | Human CD21loT-bet+ B cells: Not as easy as “ABC”! 0, 2, | | 2 | Citations (PDF) |
| 216 | Human Inherited RORγT Deficiency: Genetic Heterogeneity, Immunological Impact, and Clinical Homogeneity 0, 2, | | 0 | Citations (PDF) |
| 217 | Deleterious germline
CARD11
gain-of-function variants alter human B-cell and CD4+ T-cell differentiation and function | 2.3 | 0 | Citations (PDF) |
| 218 | Interfering with innate immunity: type I IFNs and avian influenza susceptibility | 6.6 | 0 | Citations (PDF) |
