| 1 | A break in mitochondrial endosymbiosis as a basis for inflammatory diseases | 38.7 | 99 | Citations (PDF) |
| 2 | Metabolic regulation of type I interferon production | 6.6 | 28 | Citations (PDF) |
| 3 | Metabolic Messengers: itaconate | 17.7 | 46 | Citations (PDF) |
| 4 | Macrophage fumarate hydratase restrains mtRNA-mediated interferon production | 38.7 | 185 | Citations (PDF) |
| 5 | Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon | 13.9 | 57 | Citations (PDF) |
| 6 | The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils | 13.9 | 51 | Citations (PDF) |
| 7 | Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma | 6.2 | 45 | Citations (PDF) |
| 8 | Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response | 3.6 | 92 | Citations (PDF) |
| 9 | Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages | 26.2 | 266 | Citations (PDF) |
| 10 | Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants | 3.9 | 25 | Citations (PDF) |
| 11 | Innate immune signaling and immunothrombosis: New insights and therapeutic opportunities | 3.2 | 32 | Citations (PDF) |
| 12 | Glutathione transferase Omega 1 confers protection against azoxymethane-induced colorectal tumour formation | 2.9 | 8 | Citations (PDF) |
| 13 | Targeting immunometabolism to treat COVID-19 | 4.1 | 41 | Citations (PDF) |
| 14 | 4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages | 0.6 | 25 | Citations (PDF) |
| 15 | Metabolic regulation of RA macrophages is distinct from RA fibroblasts and blockade of glycolysis alleviates inflammatory phenotype in both cell types | 5.6 | 53 | Citations (PDF) |
| 16 | ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation | 4.8 | 53 | Citations (PDF) |
| 17 | The role of the electron transport chain in immunity | 0.7 | 79 | Citations (PDF) |
| 18 | Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice | 7.6 | 64 | Citations (PDF) |
| 19 | Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity | 5.1 | 17 | Citations (PDF) |
| 20 | The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation | 26.2 | 502 | Citations (PDF) |
| 21 | The Role of HIF in Immunity and Inflammation | 26.2 | 613 | Citations (PDF) |
| 22 | Targeting immunometabolism as an anti-inflammatory strategy | 12.5 | 470 | Citations (PDF) |
| 23 | Caspase-11 promotes allergic airway inflammation | 13.9 | 71 | Citations (PDF) |
| 24 | Krebs Cycle Reborn in Macrophage Immunometabolism | 30.0 | 389 | Citations (PDF) |
| 25 | Cytokine-like Roles for Metabolites in Immunity | 13.4 | 172 | Citations (PDF) |
| 26 | A Vision for Cytokine Biology with 20/20 Clarity | 1.5 | 2 | Citations (PDF) |
| 27 | Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation | 6.4 | 82 | Citations (PDF) |
| 28 | Itaconate: the poster child of metabolic reprogramming in macrophage function | 56.7 | 555 | Citations (PDF) |
| 29 | Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β | 9.5 | 68 | Citations (PDF) |
| 30 | Metabolic regulation of <scp>NLRP</scp>3 | 6.6 | 292 | Citations (PDF) |
| 31 | Loss of MicroRNA-21 Influences the Gut Microbiota, Causing Reduced Susceptibility in a Murine Model of Colitis | 1.3 | 74 | Citations (PDF) |
| 32 | Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers | 34.1 | 337 | Citations (PDF) |
| 33 | Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2 | 7.6 | 333 | Citations (PDF) |
| 34 | Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages | 3.7 | 24 | Citations (PDF) |
| 35 | Inflammasomes in the lung | 2.3 | 152 | Citations (PDF) |
| 36 | Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma | 12.2 | 400 | Citations (PDF) |
| 37 | Mitochondria are the powerhouses of immunity | 24.2 | 992 | Citations (PDF) |
| 38 | The intracellular chloride channel proteins CLIC1 and CLIC4 induce IL-1β transcription and activate the NLRP3 inflammasome | 2.2 | 157 | Citations (PDF) |
| 39 | The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma | 3.2 | 59 | Citations (PDF) |
| 40 | The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production | 0.6 | 97 | Citations (PDF) |
| 41 | The RNA-binding protein Tristetraprolin (TTP) is a critical negative regulator of the NLRP3 inflammasome | 2.2 | 66 | Citations (PDF) |
| 42 | MyD88 is an essential component of retinoic acid-induced differentiation in human pluripotent embryonal carcinoma cells | 13.7 | 5 | Citations (PDF) |
| 43 | Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling | 7.6 | 33 | Citations (PDF) |
| 44 | Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease | 13.9 | 115 | Citations (PDF) |
| 45 | Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy | 13.9 | 136 | Citations (PDF) |
| 46 | A Potent Anti-Inflammatory Response in Bat Macrophages May Be Linked to Extended Longevity and Viral Tolerance | 0.5 | 62 | Citations (PDF) |
| 47 | GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity | 3.5 | 60 | Citations (PDF) |
| 48 | A guide to immunometabolism for immunologists | 56.7 | 2,766 | Citations (PDF) |
| 49 | Toll-like receptors and chronic inflammation in rheumatic diseases: new developments | 27.8 | 179 | Citations (PDF) |
| 50 | <i>Trypanosoma brucei</i>metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion | 7.6 | 58 | Citations (PDF) |
| 51 | A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling | 23.3 | 36 | Citations (PDF) |
| 52 | Immunometabolism governs dendritic cell and macrophage function | 9.4 | 1,514 | Citations (PDF) |
| 53 | Circadian control of innate immunity in macrophages by miR-155 targeting
<i>Bmal1</i> | 7.6 | 295 | Citations (PDF) |
| 54 | Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages | 26.2 | 1,202 | Citations (PDF) |
| 55 | A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases | 39.5 | 2,518 | Citations (PDF) |
| 56 | Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages | 2.2 | 304 | Citations (PDF) |
| 57 | GSTO1-1 modulates metabolism in macrophages activated through the LPS and TLR4 pathway | 2.5 | 63 | Citations (PDF) |
| 58 | The Cellular and Molecular Basis of Translational Immunometabolism | 23.3 | 182 | Citations (PDF) |
| 59 | The MyD88+ Phenotype Is an Adverse Prognostic Factor in Epithelial Ovarian Cancer | 2.4 | 44 | Citations (PDF) |
| 60 | Circadian Clock Proteins and Immunity | 23.3 | 571 | Citations (PDF) |
| 61 | Succinate: a metabolic signal in inflammation | 12.3 | 636 | Citations (PDF) |
| 62 | The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10 | 2.2 | 116 | Citations (PDF) |
| 63 | Glutathione transferase Omega 1 is required for the lipopolysaccharide-stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages | 3.8 | 70 | Citations (PDF) |
| 64 | Metabolism of inflammation limited by AMPK and pseudo-starvation | 38.7 | 1,063 | Citations (PDF) |
| 65 | Bruton’s Tyrosine Kinase Mediates the Synergistic Signalling between TLR9 and the B Cell Receptor by Regulating Calcium and Calmodulin | 2.4 | 56 | Citations (PDF) |
| 66 | Treatment With OPN-305, a Humanized Anti–Toll-Like Receptor-2 Antibody, Reduces Myocardial Ischemia/Reperfusion Injury in Pigs | 5.7 | 98 | Citations (PDF) |
| 67 | The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation | 13.9 | 59 | Citations (PDF) |
| 68 | Biochemical regulation of the inflammasome | 6.8 | 123 | Citations (PDF) |
| 69 | The emerging role of metabolic regulation in the functioning of Toll‐like receptors and the NOD‐like receptor Nlrp3 | 2.7 | 70 | Citations (PDF) |
| 70 | Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody | 25.2 | 339 | Citations (PDF) |
| 71 | Therapeutic Targeting of Toll-Like Receptors for Infectious and Inflammatory Diseases and Cancer | 16.0 | 401 | Citations (PDF) |
| 72 | The interleukin‐1 receptor/Toll‐like receptor superfamily: 10 years of progress | 6.6 | 581 | Citations (PDF) |
| 73 | The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling | 56.7 | 2,461 | Citations (PDF) |
| 74 | Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs | 8.3 | 160 | Citations (PDF) |
| 75 | How Toll-like receptors signal: what we know and what we don’t know | 5.3 | 579 | Citations (PDF) |
| 76 | New insights into the regulation of TLR signaling | 3.0 | 235 | Citations (PDF) |
| 77 | Immunity's Early-Warning System | 0.1 | 47 | Citations (PDF) |
| 78 | Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases | 4.0 | 155 | Citations (PDF) |
| 79 | Staurosporine, but not Ro 31-8220, induces interleukin 2 production and synergizes with interleukin 1α in EL4 thymoma cells: Activation of nuclear factor κB as a common signal for staurosporine and interleukin 1α | 3.9 | 11 | Citations (PDF) |
