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86 peer-reviewed articles • 5,084 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Incidence of liver complications with hemochromatosis associated HFE p.C282Y homozygosity: The role of central adiposity
Hepatology, 2025, 81, 10.1097/HEP.0000000000001056
11.810Citations (PDF)
2A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data
EBioMedicine, 2025, 113, 105584
6.615Citations (PDF)
3Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data
BMC Medicine, 2025, 23, 1-15
4.45Citations (PDF)
4Is Mitochondrial DNA Copy Number from Human Blood Associated with Iron Deposits in the Brain?
Antioxidants and Redox Signaling, 2024, 40, 990-997
4.22Citations (PDF)
5HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank
BMJ Open, 2024, 14, e081926
1.241Citations (PDF)
6SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients
International Journal of Molecular Sciences, 2024, 25, 4426
3.26Citations (PDF)
7Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone
Pharmacogenomics Journal, 2024, 24, 1-7
1.46Citations (PDF)
8Proteomic aging clock (PAC) predicts age-related outcomes in middle-aged and older adults
Aging Cell, 2024, 23, e14195
4.873Citations (PDF)
9MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort
Neurobiology of Disease, 2024, 197, 106539
3.628Citations (PDF)
10Mitochondrial DNA copy number associated dementia risk by somatic mutations and frailty
GeroScience, 2024, 47, 1-11
3.35Citations (PDF)
11Calcium-channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients
British Journal of Clinical Pharmacology, 2023, 89, 853-864
1.511Citations (PDF)
12Letter to the editor regarding: “A haemochromatosis-causing HFE mutation is associated with SARS-CoV-2 susceptibility in the Czech population” clinica chimica acta 538 (2023) 211–215
Clinica Chimica Acta, 2023, 542, 117271
0.72Citations (PDF)
13Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study
Toxics, 2023, 11, 489
3.12Citations (PDF)
14Hemochromatosis Genetic Variants and Musculoskeletal Outcomes: 11.5-Year Follow-Up in the UK Biobank Cohort Study
JBMR Plus, 2023, 7, e10794
1.515Citations (PDF)
15Does physical activity moderate the association between shorter leukocyte telomere length and incident coronary heart disease? Data from 54,180 UK Biobank participants
GeroScience, 2023, 46, 1-12
3.31Citations (PDF)
16APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2022, 77, 879-880
2.517Citations (PDF)
17Statin treatment effectiveness and the SLCO1B1*5 reduced function genotype: Long-term outcomes in women and men
British Journal of Clinical Pharmacology, 2022, 88, 3230-3240
1.517Citations (PDF)
18Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: Associations in a large community cohort
Hepatology, 2022, 76, 1735
11.824Citations (PDF)
19Hereditary Hemochromatosis Variant Associations with Incident Nonliver Malignancies: 11-Year Follow-up in UK Biobank
Cancer Epidemiology Biomarkers and Prevention, 2022, 31, 1780-1787
0.611Citations (PDF)
20Genomics and multimorbidity.
Age and Ageing, 2022
1.210Citations (PDF)
21Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older UK Biobank Participants
Journal of the American Geriatrics Society, 2021, 69, 365-372
2.234Citations (PDF)
22Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women
Nature Communications, 2021, 12, 1-11
11.0207Citations (PDF)
23Log in to my account
Journal of Alzheimer's Disease, 2021, 79, 1203-1211
1.744Citations (PDF)
24Biological Aging Predicts Vulnerability to COVID-19 Severity in UK Biobank Participants
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2021, 76, e133-e141
2.556Citations (PDF)
25Genetic associations for two biological age measures point to distinct aging phenotypes
Aging Cell, 2021, 20, e13376
4.8171Citations (PDF)
26A genome-wide association study of the frailty index highlights brain pathways in ageing
Aging Cell, 2021, 20, e13459
4.8305Citations (PDF)
27The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research
PLoS Genetics, 2021, 17, e1009783
2.221Citations (PDF)
28Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study
BMJ Open, 2021, 11, e053905
1.214Citations (PDF)
29Sarcopenia and Variation in the Human Leukocyte Antigen Complex
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2020, 75, 301-308
2.533Citations (PDF)
30The Longevity-Associated SH2B3 (LNK) Genetic Variant: Selected Aging Phenotypes in 379,758 Subjects.
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2020, 75, 1656-1662
2.521Citations (PDF)
31Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort.
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2020, 75, 2224-2230
2.5433Citations (PDF)
32The relationship of parental longevity with the aging brain—results from UK Biobank
GeroScience, 2020, 42, 1377-1385
3.314Citations (PDF)
33Association of Hemochromatosis HFE p.C282Y Homozygosity With Hepatic Malignancy
JAMA - Journal of the American Medical Association, 2020, 324, 2048-2057
19.583Citations (PDF)
34ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2020, 75, 1801-1803
2.5102Citations (PDF)
35APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2020, 75, 2231-2232
2.5339Citations (PDF)
36Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2019, 74, 350-357
2.536Citations (PDF)
37Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease
Circulation, 2019, 140, 645-657
13.2218Citations (PDF)
38The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood
Biogerontology, 2019, 20, 649-663
3.123Citations (PDF)
39Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants
Aging Cell, 2019, 18, e13017
4.8101Citations (PDF)
40Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2019, 74, 337-342
2.539Citations (PDF)
41Vitamin D levels and risk of deliriumA mendelian randomization study in the UK Biobank
Neurology, 2019, 92, e1387-e1394
0.750Citations (PDF)
42ABO GENE AND AGING-RELATED OUTCOMES IN OVER 379,000 EUROPEAN-DESCENT PARTICIPANTS OF UK BIOBANK
Innovation in Aging, 2019, 3, S925-S925
0.10Citations (PDF)
43CAUSES OF FRAILTY: GENETIC ANALYSIS IN 164,000 UK BIOBANK PARTICIPANTS
Innovation in Aging, 2019, 3, S222-S222
0.10Citations (PDF)
44The genetics of human ageing
Nature Reviews Genetics, 2019, 21, 88-101
29.7368Citations (PDF)
45circRNAs expressed in human peripheral blood are associated with human aging phenotypes, cellular senescence and mouse lifespan
GeroScience, 2019, 42, 183-199
3.353Citations (PDF)
46The VEGFA156b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease
Clinical Science, 2018, 132, 313-325
4.123Citations (PDF)
47Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years
PLoS ONE, 2018, 13, e0203504
1.581Citations (PDF)
48Clinical Outcomes of CADASIL-Associated NOTCH3 Mutations in 451,424 European Ancestry Community Volunteers
Translational Stroke Research, 2018, 10, 339-341
2.19Citations (PDF)
49Genome-wide Association Study of Parental Life Span.
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2017, 72, 1407-1410
2.58Citations (PDF)
50Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers
PLoS ONE, 2017, 12, e0185083
1.570Citations (PDF)
51DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
Genome Biology, 2016, 17, 1-15
4.8341Citations (PDF)
52Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons
Physiological Genomics, 2016, 48, 1-11
1.412Citations (PDF)
53Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans
Aging Cell, 2016, 15, 903-913
4.8113Citations (PDF)
54Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations
Diabetes, 2016, 65, 3794-3804
3.426Citations (PDF)
55Epigenetic Signatures of Cigarette Smoking
Circulation: Cardiovascular Genetics, 2016, 9, 436-447
3.7905Citations (PDF)
56Change in Epigenome-Wide DNA Methylation Over 9 Years and Subsequent Mortality: Results From the InCHIANTI Study.
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2016, 71, 1029-35
2.538Citations (PDF)
57DNA Methylation of Lipid-Related Genes Affects Blood Lipid Levels
Circulation: Cardiovascular Genetics, 2015, 8, 334-42
3.7174Citations (PDF)
58Comparison of senescence-associated miRNAs in primary skin and lung fibroblasts
Biogerontology, 2015, 16, 423-434
3.115Citations (PDF)
59Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise
Journal of Physiological Sciences, 2015, 65, 145-150
1.714Citations (PDF)
60Gene expression markers of age-related inflammation in two human cohorts
Experimental Gerontology, 2015, 70, 37-45
2.926Citations (PDF)
61A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension
PLoS Genetics, 2015, 11, e1005035
2.2131Citations (PDF)
62The transcriptional landscape of age in human peripheral blood
Nature Communications, 2015, 6, 1-14
11.0748Citations (PDF)
63PFOA and PFOS are associated with reduced expression of the parathyroid hormone 2 receptor () gene in women
Chemosphere, 2015, 120, 555-562
5.121Citations (PDF)
64Whole blood gene expression and interleukin-6 levels
Genomics, 2014, 104, 490-495
2.026Citations (PDF)
65Clinical Relevance of Increased Endothelial and Mesothelial Expression of Proangiogenic Proteases and VEGFA in the Omentum of Patients with Metastatic Ovarian High-Grade Serous Carcinoma
Translational Oncology, 2014, 7, 267-276.e4
2.822Citations (PDF)
66Splicing factor 3B1 hypomethylation is associated with altered transcript expression in older humans
Mechanisms of Ageing and Development, 2014, 135, 50-56
3.97Citations (PDF)
67Associations between PFOA, PFOS and changes in the expression of genes involved in cholesterol metabolism in humans
Environment International, 2013, 57, 2-10
6.7176Citations (PDF)
68Changes in splicing factor expression are associated with advancing age in man
Mechanisms of Ageing and Development, 2013, 134, 356-366
3.9114Citations (PDF)
69Towards a gene expression biomarker set for human biological age
Aging Cell, 2013, 12, 324-326
4.877Citations (PDF)
70Uric Acid Measurement Improves Prediction of Cardiovascular Mortality in Later Life
Journal of the American Geriatrics Society, 2013, 61, 319-326
2.253Citations (PDF)
71Annual Review of Gerontology and Geriatrics
Annual Review of Gerontology and Geriatrics, 2013, 33, 233-258
0.11Citations (PDF)
72Leukocyte CCR2 Expression Is Associated with Mini-Mental State Examination Score in Older Adults
Rejuvenation Research, 2012, 15, 395-404
1.038Citations (PDF)
73CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength
Aging Cell, 2012, 11, 262-268
4.825Citations (PDF)
74Advancing age is associated with gene expression changes resembling mTOR inhibition: Evidence from two human populations
Mechanisms of Ageing and Development, 2012, 133, 556-562
3.957Citations (PDF)
75Genomics and successful aging: grounds for renewed optimism?
Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 2012, 67, 511-9
2.516Citations (PDF)
76A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking.
Human Molecular Genetics, 0, 25, 4611-4623
2.182Citations (PDF)
77Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank
BMJ: British Medical Journal, 0, 364, k5222
0.1183Citations (PDF)
78Age related changes in mTOR-related gene expression in two primary human cell lines
Healthy Aging Research, 0
0.21Citations (PDF)
79Predictors of MRI-estimated brain iron deposition in dementia and Parkinson's disease-associated subcortical regions: Genetic and observational analysis in UK Biobank
Journal of Alzheimer's Disease, 0, 108, 107-118
1.71Citations (PDF)
80Chondrocalcinosis and the haemochromatosis-linked HFE C282Y homozygous variant in the UK Biobank.
EULAR Rheumatology Open, 0, 2, 1-8
0.00Citations (PDF)
81Getting to GRIPS with MR-Egger: Modelling directional pleiotropy independently of allele coding
PLoS Genetics, 0, 21, e1011967
2.22Citations (PDF)
82Liver iron levels are associated with HFE-hemochromatosis genotype, diet, adiposity, and disease in the UK Biobank
Hepatology Communications, 0, 10, e0883
3.32Citations (PDF)
83Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions
Communications Medicine, 0, 6, 67
3.60Citations (PDF)
84Genetic and lifestyle modifiers of haemochromatosis-related clinical outcomes in HFE C282Y homozygotes.
JHEP Reports, 0, 8, 101781
3.51Citations (PDF)
85Plasma GDF15 affects long-term dementia risk and alters neuroimmune signaling.
Science Advances, 0, 12, eaec7614
8.22Citations (PDF)
86Hormone replacement therapy and dementia risk among postmenopausal women: Identifying responsive subgroups in the UK Biobank
Alzheimer's and Dementia, 0, 22, e71679
0.90Citations (PDF)