| 1 | Factors to consider when designing post-hospital interventions to support critical illness recovery: Systematic review and qualitative evidence synthesis | 1.0 | 6 | Citations (PDF) |
| 2 | Preoperative inflammatory subphenotypes predict postoperative pulmonary complications in patients undergoing elective major surgery: a secondary analysis of the Prevention-HARP2 trial | 3.6 | 1 | Citations (PDF) |
| 3 | Effect of statins on neurological functional outcomes in critically ill adult patients with traumatic brain injury: a systematic review and meta-analysis | 1.2 | 5 | Citations (PDF) |
| 4 | Sepsis subphenotypes, theragnostics and personalized sepsis care | 3.5 | 67 | Citations (PDF) |
| 5 | Cell-based Therapies for Acute Respiratory Distress Syndrome: Where Are We Now? | 5.0 | 23 | Citations (PDF) |
| 6 | Vascular leak in sepsis: physiological basis and potential therapeutic advances | 4.1 | 119 | Citations (PDF) |
| 7 | Recovery following discharge from intensive care: What do patients think is helpful and what services are missing? | 1.5 | 19 | Citations (PDF) |
| 8 | Communication in critical care tracheostomy patients dependent upon cuff inflation: A scoping review | 2.1 | 6 | Citations (PDF) |
| 9 | TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells | 2.8 | 11 | Citations (PDF) |
| 10 | Neutrophil-Derived Proteases in Lung Inflammation: Old Players and New Prospects | 3.2 | 35 | Citations (PDF) |
| 11 | Statistical Power and Performance of Strategies to Analyze Composites of Survival and Duration of Ventilation in Clinical Trials 2024, 6, e1152 | | 1 | Citations (PDF) |
| 12 | SIGNET: protocol for a multicentre, single-blind prospective, group sequential, randomised controlled trial to evaluate the benefits of a single dose of simvastatin given to potential organ donors declared dead by neurological criteria on outcomes in organ recipients | 1.2 | 6 | Citations (PDF) |
| 13 | Small volume fluid resuscitation and supplementation with 20% albumin versus buffered crystalloids in adults with septic shock: A protocol for a randomised feasibility trial | 1.0 | 1 | Citations (PDF) |
| 14 | A randomized control trial evaluating the advice of a physiological-model/digital twin-based decision support system on mechanical ventilation in patients with acute respiratory distress syndrome | 1.6 | 9 | Citations (PDF) |
| 15 | Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial | 2.2 | 16 | Citations (PDF) |
| 16 | Quantitative oral health assessments in mechanically ventilated patients: A scoping review | 2.2 | 8 | Citations (PDF) |
| 17 | Diabetic Macular Edema and Diode Subthreshold Micropulse Laser | 5.8 | 52 | Citations (PDF) |
| 18 | Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis | 3.4 | 46 | Citations (PDF) |
| 19 | Acute hypoxaemic respiratory failure after treatment with lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal: long-term outcomes from the REST randomised trial | 3.4 | 7 | Citations (PDF) |
| 20 | Re-analysis of ventilator-free days (VFD) in acute respiratory distress syndrome (ARDS) studies | 1.1 | 11 | Citations (PDF) |
| 21 | Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials | 4.1 | 32 | Citations (PDF) |
| 22 | Determinants of Effect of Extracorporeal CO
2
Removal in Hypoxemic Respiratory Failure | 5.3 | 31 | Citations (PDF) |
| 23 | Oral health care in adult intensive care units: A national point prevalence study | 2.2 | 24 | Citations (PDF) |
| 24 | Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study | 1.4 | 14 | Citations (PDF) |
| 25 | A reply to analysis of static parameters in retrospective studies: limitations and interpretation | 4.1 | 0 | Citations (PDF) |
| 26 | Delivery of a novel intervention to facilitate liberation from mechanical ventilation in paediatric intensive care: A process evaluation | 1.5 | 2 | Citations (PDF) |
| 27 | Do critical illness survivors with multimorbidity need a different model of care? | 4.1 | 43 | Citations (PDF) |
| 28 | Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK | 1.2 | 9 | Citations (PDF) |
| 29 | Inhibition of bradykinin in SARS-CoV-2 infection: a randomised, double-blind trial of icatibant compared with placebo (ICASARS) | 1.2 | 0 | Citations (PDF) |
| 30 | Advancing precision medicine for acute respiratory distress syndrome | 15.9 | 196 | Citations (PDF) |
| 31 | “Sugar or Salt” (SOS) trial protocol summary | 1.0 | 1 | Citations (PDF) |
| 32 | Aspirin as a Treatment for ARDSChest, 2022, 161, 1275-1284 | 0.8 | 19 | Citations (PDF) |
| 33 | Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome | 5.0 | 36 | Citations (PDF) |
| 34 | Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis | 15.9 | 179 | Citations (PDF) |
| 35 | Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19 | 14.4 | 354 | Citations (PDF) |
| 36 | Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report | 2.1 | 247 | Citations (PDF) |
| 37 | Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies | 9.7 | 45 | Citations (PDF) |
| 38 | A randomised trial of the effects on recruitment and retention of including a wet-ink signature and photograph in the patient invitation letter for a clinical trial: results from a Study Within a Trial (SWAT 3 and SWAT 53) | 0.3 | 2 | Citations (PDF) |
| 39 | Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, phase 2, proof-of-concept trial | 15.9 | 56 | Citations (PDF) |
| 40 | Towards a biological definition of ARDS: are treatable traits the solution? | 1.3 | 51 | Citations (PDF) |
| 41 | Whole-genome sequencing reveals host factors underlying critical COVID-19 | 30.6 | 315 | Citations (PDF) |
| 42 | Management of new onset atrial fibrillation in critically unwell adult patients: a systematic review and narrative synthesis | 3.6 | 29 | Citations (PDF) |
| 43 | Patients views on a new surveillance pathway involving allied non-medical staff for people with treated diabetic macular oedema and proliferative diabetic retinopathy | 1.9 | 1 | Citations (PDF) |
| 44 | Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients | 6.6 | 30 | Citations (PDF) |
| 45 | Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial | 4.1 | 33 | Citations (PDF) |
| 46 | Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery | 0.4 | 5 | Citations (PDF) |
| 47 | The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium | 2.6 | 5 | Citations (PDF) |
| 48 | Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management | 46.9 | 388 | Citations (PDF) |
| 49 | Extracorporeal carbon dioxide removal in acute hypoxaemic respiratory failure: a systematic review, Bayesian meta-analysis and trial sequential analysis | 4.7 | 8 | Citations (PDF) |
| 50 | Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis) | 1.2 | 8 | Citations (PDF) |
| 51 | Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential | 1.7 | 58 | Citations (PDF) |
| 52 | Evaluation of a New Model of Care for People with Complications of Diabetic Retinopathy | 5.8 | 25 | Citations (PDF) |
| 53 | Swallowing therapy compared to standard care may not have had a beneficial effect on the incidence of pneumonia for patients in acute care. Author’s reply | 3.5 | 0 | Citations (PDF) |
| 54 | Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 | 26.4 | 1,792 | Citations (PDF) |
| 55 | Death in hospital following ICU discharge: insights from the LUNG SAFE study | 4.1 | 18 | Citations (PDF) |
| 56 | Moral distress in end-of-life decisions: A qualitative study of intensive care physicians | 1.0 | 71 | Citations (PDF) |
| 57 | Targeting Candida albicans in dual-species biofilms with antifungal treatment reduces Staphylococcus aureus and MRSA in vitro | 1.5 | 30 | Citations (PDF) |
| 58 | The future of acute and emergency care | 0.4 | 3 | Citations (PDF) |
| 59 | Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 | 26.4 | 977 | Citations (PDF) |
| 60 | Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units | 14.4 | 93 | Citations (PDF) |
| 61 | Secreted Extracellular Cyclophilin A Is a Novel Mediator of Ventilator-induced Lung Injury | 5.0 | 16 | Citations (PDF) |
| 62 | Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 | 26.4 | 896 | Citations (PDF) |
| 63 | Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure | 14.4 | 213 | Citations (PDF) |
| 64 | Hyperoxaemia and hypoxaemia are associated with harm in patients with ARDS | 1.5 | 24 | Citations (PDF) |
| 65 | Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine | 26.4 | 1,039 | Citations (PDF) |
| 66 | Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression | 4.1 | 65 | Citations (PDF) |
| 67 | Oral health care for the critically ill: a narrative review | 4.1 | 61 | Citations (PDF) |
| 68 | Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS | 6.5 | 238 | Citations (PDF) |
| 69 | Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study | 6.5 | 73 | Citations (PDF) |
| 70 | Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19 | 14.4 | 211 | Citations (PDF) |
| 71 | Characterizing preclinical sub‐phenotypic models of acute respiratory distress syndrome: An experimental ovine study | 1.1 | 19 | Citations (PDF) |
| 72 | Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial | 6.6 | 38 | Citations (PDF) |
| 73 | Promises and challenges of personalized medicine to guide ARDS therapy | 4.1 | 63 | Citations (PDF) |
| 74 | Comparison of machine learning clustering algorithms for detecting heterogeneity of treatment effect in acute respiratory distress syndrome: A secondary analysis of three randomised controlled trials | 6.6 | 54 | Citations (PDF) |
| 75 | Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity | 1.8 | 34 | Citations (PDF) |
| 76 | Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial | 3.5 | 62 | Citations (PDF) |
| 77 | Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential | 5.0 | 62 | Citations (PDF) |
| 78 | Fluid management and deresuscitation practices: A survey of critical care physicians | 1.0 | 48 | Citations (PDF) |
| 79 | Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation | 15.9 | 106 | Citations (PDF) |
| 80 | The National Institute for Health Research Critical Care Research Priority Setting Survey 2018 | 1.0 | 6 | Citations (PDF) |
| 81 | A nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study | 3.4 | 10 | Citations (PDF) |
| 82 | Emerging pharmacological therapies for ARDS: COVID-19 and beyond | 3.5 | 82 | Citations (PDF) |
| 83 | The Impact of Aging in Acute Respiratory Distress Syndrome: A Clinical and Mechanistic Overview | 1.6 | 38 | Citations (PDF) |
| 84 | A minimal common outcome measure set for COVID-19 clinical research | 9.2 | 1,506 | Citations (PDF) |
| 85 | RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a randomised controlled trial | 1.1 | 37 | Citations (PDF) |
| 86 | Subphenotypes in critical care: translation into clinical practice | 15.9 | 229 | Citations (PDF) |
| 87 | Comparing regression and neural network techniques for personalized predictive analytics to promote lung protective ventilation in Intensive Care Units | 4.5 | 23 | Citations (PDF) |
| 88 | Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19 | 14.4 | 799 | Citations (PDF) |
| 89 | Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study | 15.9 | 233 | Citations (PDF) |
| 90 | Airway Inflammation and Host Responses in the Era of CFTR Modulators | 3.2 | 54 | Citations (PDF) |
| 91 | Reply to Zhang and Hei: Mesenchymal Stem Cell–derived Exosomes: Are They Another Therapeutic Method for Extracorporeal Membrane Oxygenation–supported Acute Respiratory Distress Syndrome? | 5.0 | 0 | Citations (PDF) |
| 92 | Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis | 3.5 | 74 | Citations (PDF) |
| 93 | Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial | 1.1 | 28 | Citations (PDF) |
| 94 | Mucoactive agents for acute respiratory failure in the critically ill: a systematic review and meta-analysis | 3.4 | 20 | Citations (PDF) |
| 95 | Relationship between norepinephrine dose, tachycardia and outcome in septic shock: A multicentre evaluation | 1.0 | 67 | Citations (PDF) |
| 96 | Airway clearance techniques and use of mucoactive agents for adult critically ill patients with acute respiratory failure: a qualitative study exploring UK physiotherapy practice | 1.2 | 18 | Citations (PDF) |
| 97 | Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials | 15.9 | 297 | Citations (PDF) |
| 98 | Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep | 5.0 | 30 | Citations (PDF) |
| 99 | Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation | 6.5 | 101 | Citations (PDF) |
| 100 | Genetic mechanisms of critical illness in COVID-19 | 30.6 | 1,293 | Citations (PDF) |
| 101 | Prospective Investigation of Markers of Elevated Delirium Risk (PRIMED Risk) study protocol: a prospective, observational cohort study investigating blood and cerebrospinal fluid biomarkers for delirium and cognitive dysfunction in older patients | 0.9 | 2 | Citations (PDF) |
| 102 | Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study* | 0.5 | 94 | Citations (PDF) |
| 103 | Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial | 3.5 | 54 | Citations (PDF) |
| 104 | Effectiveness of Multimodal imaging for the Evaluation of Retinal oedema And new vesseLs in Diabetic retinopathy (EMERALD) | 1.2 | 7 | Citations (PDF) |
| 105 | Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models | 1.3 | 24 | Citations (PDF) |
| 106 | Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials | 4.1 | 36 | Citations (PDF) |
| 107 | Emerging drugs for treating the acute respiratory distress syndrome | 2.0 | 62 | Citations (PDF) |
| 108 | IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses
In Vivo | 5.0 | 52 | Citations (PDF) |
| 109 | Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery | 2.7 | 27 | Citations (PDF) |
| 110 | A Porcine
Ex Vivo
Lung Perfusion Model To Investigate Bacterial Pathogenesis | 3.1 | 29 | Citations (PDF) |
| 111 | Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial | 1.2 | 17 | Citations (PDF) |
| 112 | A Core Outcome Set for Critical Care Ventilation Trials | 0.5 | 94 | Citations (PDF) |
| 113 | Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair | 2.3 | 46 | Citations (PDF) |
| 114 | Patients’ Perceptions of an Exercise Program Delivered Following Discharge From Hospital After Critical Illness (the Revive Trial) | 1.4 | 26 | Citations (PDF) |
| 115 | CSF Beta-amyloid 1–42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study | 3.4 | 89 | Citations (PDF) |
| 116 | Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children | 1.7 | 27 | Citations (PDF) |
| 117 | High-volume haemofiltration for sepsis in adults | 1.7 | 60 | Citations (PDF) |
| 118 | Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? | 2.1 | 24 | Citations (PDF) |
| 119 | Late mortality after acute hypoxic respiratory failure | 3.4 | 32 | Citations (PDF) |
| 120 | Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study | 3.5 | 316 | Citations (PDF) |
| 121 | Deresuscitation of Patients With Iatrogenic Fluid Overload Is Associated With Reduced Mortality in Critical Illness* | 0.5 | 168 | Citations (PDF) |
| 122 | Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future | 15.9 | 70 | Citations (PDF) |
| 123 | Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database | 4.1 | 35 | Citations (PDF) |
| 124 | Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure | 14.4 | 99 | Citations (PDF) |
| 125 | A United Kingdom Register study of in-hospital outcomes of patients receiving extracorporeal carbon dioxide removal | 1.0 | 6 | Citations (PDF) |
| 126 | Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial | 15.9 | 706 | Citations (PDF) |
| 127 | Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis | 3.4 | 70 | Citations (PDF) |
| 128 | The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis | 3.5 | 99 | Citations (PDF) |
| 129 | Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis | 4.1 | 19 | Citations (PDF) |
| 130 | Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial) | 3.4 | 75 | Citations (PDF) |
| 131 | 16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia | 3.4 | 37 | Citations (PDF) |
| 132 | An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome | 5.0 | 1,425 | Citations (PDF) |
| 133 | Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study | 15.9 | 116 | Citations (PDF) |
| 134 | Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial | 15.9 | 80 | Citations (PDF) |
| 135 | Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer | 5.0 | 732 | Citations (PDF) |
| 136 | Clinical trials in acute respiratory distress syndrome: challenges and opportunities | 15.9 | 265 | Citations (PDF) |
| 137 | Observational cohort study examining apolipoprotein E status and preoperative neuropsychological performance as predictors of post-operative delirium in an older elective arthroplasty population | 1.2 | 29 | Citations (PDF) |
| 138 | Evidence for chemokine synergy during neutrophil migration in ARDS | 3.4 | 111 | Citations (PDF) |
| 139 | Mechanical Ventilation in Adults with Acute Respiratory Distress Syndrome. Summary of the Experimental Evidence for the Clinical Practice Guideline | 2.1 | 60 | Citations (PDF) |
| 140 | Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial | 15.9 | 70 | Citations (PDF) |
| 141 | Characterisation of eppin function: expression and activity in the lung | 6.5 | 6 | Citations (PDF) |
| 142 | Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching* | 0.5 | 49 | Citations (PDF) |
| 143 | Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study | 5.0 | 577 | Citations (PDF) |
| 144 | The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology | 4.1 | 756 | Citations (PDF) |
| 145 | Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation | 3.4 | 70 | Citations (PDF) |
| 146 | Acute respiratory distress syndrome | 46.9 | 371 | Citations (PDF) |
| 147 | Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis | 26.4 | 353 | Citations (PDF) |
| 148 | Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS | 2.7 | 539 | Citations (PDF) |
| 149 | Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study | 3.5 | 313 | Citations (PDF) |
| 150 | Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries | 14.4 | 5,119 | Citations (PDF) |
| 151 | Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness | 4.4 | 30 | Citations (PDF) |
| 152 | Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome | 5.0 | 107 | Citations (PDF) |
| 153 | Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials | 3.5 | 39 | Citations (PDF) |
| 154 | Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis | 3.5 | 392 | Citations (PDF) |
| 155 | A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair | 1.3 | 7 | Citations (PDF) |
| 156 | Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis | 4.1 | 78 | Citations (PDF) |
| 157 | Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis | 4.1 | 95 | Citations (PDF) |
| 158 | Sedation/drugs used in intensive care sedation | 1.4 | 12 | Citations (PDF) |
| 159 | Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation | 8.7 | 177 | Citations (PDF) |
| 160 | Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia | 3.4 | 79 | Citations (PDF) |
| 161 | Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD | 1.5 | 32 | Citations (PDF) |
| 162 | The Beta Agonist Lung Injury Trial Prevention. A Randomized Controlled Trial | 5.0 | 73 | Citations (PDF) |
| 163 | Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy | 3.4 | 43 | Citations (PDF) |
| 164 | Biological therapies in the acute respiratory distress syndrome | 1.9 | 31 | Citations (PDF) |
| 165 | Statin Use and Risk of Delirium in the Critically Ill | 5.0 | 92 | Citations (PDF) |
| 166 | Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation | 2.2 | 144 | Citations (PDF) |
| 167 | Clinical Trial Design in Prevention and Treatment of Acute Respiratory Distress Syndrome | 1.6 | 1 | Citations (PDF) |
| 168 | Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress syndrome: a systematic review | 4.1 | 84 | Citations (PDF) |
| 169 | Simvastatin in the Acute Respiratory Distress Syndrome | 26.4 | 447 | Citations (PDF) |
| 170 | Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia | 3.4 | 145 | Citations (PDF) |
| 171 | Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury | 5.0 | 112 | Citations (PDF) |
| 172 | SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro | 1.8 | 21 | Citations (PDF) |
| 173 | The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index | 2.5 | 730 | Citations (PDF) |
| 174 | How Outcomes Are Defined in Clinical Trials of Mechanically Ventilated Adults and Children | 5.0 | 58 | Citations (PDF) |
| 175 | Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis | 3.5 | 108 | Citations (PDF) |
| 176 | Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial | 15.9 | 379 | Citations (PDF) |
| 177 | Pharmacological treatments in ARDS; a state-of-the-art update | 4.4 | 152 | Citations (PDF) |
| 178 | Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury | 3.3 | 29 | Citations (PDF) |
| 179 | Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre‐clinical models | 2.4 | 56 | Citations (PDF) |
| 180 | Clinical review: Statins and trauma - a systematic review | 4.1 | 23 | Citations (PDF) |
| 181 | Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury | 1.5 | 20 | Citations (PDF) |
| 182 | A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation | 5.0 | 21 | Citations (PDF) |
| 183 | Treatment of Acute Lung Injury: Current and Emerging Pharmacological Therapies | 1.8 | 64 | Citations (PDF) |
| 184 | Moral distress in end‐of‐life care in the intensive care unit | 2.6 | 58 | Citations (PDF) |
| 185 | Role Responsibilities in Mechanical Ventilation and Weaning in Pediatric Intensive Care Units: A National Survey | 0.8 | 32 | Citations (PDF) |
| 186 | Ventilator-Associated Pneumonia Is Characterized by Excessive Release of Neutrophil Proteases in the LungChest, 2012, 142, 1425-1432 | 0.8 | 601 | Citations (PDF) |
| 187 | Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial | 46.9 | 328 | Citations (PDF) |
| 188 | Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study | 4.1 | 7 | Citations (PDF) |
| 189 | Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice | 2.6 | 3 | Citations (PDF) |
| 190 | Decisional responsibility for mechanical ventilation and weaning: an international survey | 4.1 | 77 | Citations (PDF) |
| 191 | Translational research | 1.8 | 18 | Citations (PDF) |
| 192 | Referral to an Extracorporeal Membrane Oxygenation Center and Mortality Among Patients With Severe 2009 Influenza A(H1N1) | 14.4 | 787 | Citations (PDF) |
| 193 | Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury | 2.8 | 16 | Citations (PDF) |
| 194 | A Randomized Clinical Trial of Hydroxymethylglutaryl– Coenzyme A Reductase Inhibition for Acute Lung Injury (The HARP Study) | 5.0 | 189 | Citations (PDF) |
| 195 | Sequelae and rehabilitation after critical illness | 0.7 | 7 | Citations (PDF) |
| 196 | Acute Lung Failure | 1.8 | 23 | Citations (PDF) |
| 197 | Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat | 1.5 | 40 | Citations (PDF) |
| 198 | Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo | 1.5 | 104 | Citations (PDF) |
| 199 | A stepwise approach to justify phase III randomized clinical trials and enhance the likelihood of a positive result | 0.5 | 18 | Citations (PDF) |
| 200 | Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury* | 0.5 | 133 | Citations (PDF) |
| 201 | Helium-oxygen reduces the production of carbon dioxide during weaning from mechanical ventilation | 2.8 | 0 | Citations (PDF) |
| 202 | Assessing the quantity of pulmonary edema in critically ill children | 4.1 | 4 | Citations (PDF) |
| 203 | Beta 2 antagonism in acute respiratory failure | 4.1 | 0 | Citations (PDF) |
| 204 | Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers | 5.0 | 235 | Citations (PDF) |
| 205 | Comment on “Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury” | 3.5 | 5 | Citations (PDF) |
| 206 | Type XVIII collagen degradation products in acute lung injury | 4.1 | 13 | Citations (PDF) |
| 207 | Preliminary Results of a Prospective Randomized Trial of Restrictive Versus Standard Fluid Regime in Elective Open Abdominal Aortic Aneurysm Repair | 3.4 | 114 | Citations (PDF) |
| 208 | Simvastatin as a Potential Therapeutic for Acute Respiratory Distress Syndrome | 5.0 | 1 | Citations (PDF) |
| 209 | KL-6 in acute lung injury: will it leave its mark? | 4.1 | 1 | Citations (PDF) |
| 210 | Does MMP-12 Play a Role in Human Lung Fibrosis? | 2.1 | 2 | Citations (PDF) |
| 211 | Acute polyneuropathy | 0.4 | 0 | Citations (PDF) |
| 212 | Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury | 2.2 | 185 | Citations (PDF) |
| 213 | Selenium in critical illness | 1.8 | 52 | Citations (PDF) |
| 214 | New flow cytometric technique for the evaluation of circulating endothelial progenitor cell levels in various disease groups | 1.0 | 9 | Citations (PDF) |
| 215 | The β-Agonist Lung Injury Trial (BALTI) | 5.0 | 485 | Citations (PDF) |
| 216 | Title is missing! | 4.1 | 68 | Citations (PDF) |
| 217 | Title is missing! | 4.1 | 123 | Citations (PDF) |
| 218 | Training in the management of the acutely ill medical patient | 0.7 | 7 | Citations (PDF) |
| 219 | What is the optimal duration of ventilation in the prone position in acute lung injury and acute respiratory distress syndrome? | 3.5 | 98 | Citations (PDF) |
| 220 | Hyperhomocysteinaemia in young adults is not associated with impaired endothelial function | 4.1 | 9 | Citations (PDF) |
| 221 | The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia | 1.6 | 7 | Citations (PDF) |
| 222 | Vasoconstriction to endogenous endothelin-1 is impaired in patients with Type II diabetes mellitus | 4.1 | 20 | Citations (PDF) |
| 223 | Vasoconstriction to endogenous endothelin-1 is impaired in patients with Type II diabetes mellitus | 4.1 | 17 | Citations (PDF) |
| 224 | Vasoconstriction to Endothelin-1 is Blunted in Non-Insulin-Dependent Diabetes: A Dose-Response Study | 1.4 | 21 | Citations (PDF) |
| 225 | Effect of Methionine Supplementation on Endothelial Function, Plasma Homocysteine, and Lipid Peroxidation | 1.4 | 13 | Citations (PDF) |
| 226 | Epidemiology and treatment of left ventricular hypertrophy in the elderly | 1.2 | 4 | Citations (PDF) |
| 227 | Sources of inaccuracy in the use of the Hawksley random-zero sphygmomanometer | 1.8 | 12 | Citations (PDF) |
| 228 | Current practice in the management of new-onset atrial fibrillation in critically ill patients: a UK-wide survey | 0.0 | 40 | Citations (PDF) |
| 229 | Fool’s gold? Why blinded trials are not always best | 0.2 | 43 | Citations (PDF) |
| 230 | Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome | 3.4 | 3 | Citations (PDF) |
| 231 | Mucoactive agent use in adult UK Critical Care Units: a survey of health care professionals’ perception, pharmacists’ description of practice, and point prevalence of mucoactive use in invasively mechanically ventilated patients | 0.0 | 12 | Citations (PDF) |
| 232 | Heterogeneous Treatment Effects of Extracorporeal CO2 Removal in Acute Hypoxemic Respiratory Failure | 5.0 | 5 | Citations (PDF) |
| 233 | Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial | 0.5 | 3 | Citations (PDF) |
| 234 | Effect of simvastatin on postoperative complications in patients undergoing one-lung ventilation during surgery: the Prevention HARP-2 randomised controlled trial | 3.4 | 0 | Citations (PDF) |
| 235 | Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction. | 0.5 | 2 | Citations (PDF) |
| 236 | Extracorporeal carbon dioxide removal for the treatment of acute hypoxaemic respiratory failure: the REST RCT | 1.1 | 1 | Citations (PDF) |
| 237 | Hypertonic Saline or Carbocisteine in Bronchiectasis | 26.4 | 34 | Citations (PDF) |
| 238 | Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction. | 0.5 | 0 | Citations (PDF) |
| 239 | Safety and efficacy of inhaled PEG-ADM in ARDS patients: a randomised controlled trial | 4.1 | 2 | Citations (PDF) |
| 240 | Vasoactive support in cardiogenic shock: a systematic review of randomised controlled trials | 3.6 | 0 | Citations (PDF) |
| 241 | Measuring physical activity, sedentary behaviour and physical function in survivors of critical illness in the year after hospital discharge: a prospective, observational study | 0.2 | 0 | Citations (PDF) |
| 242 | Who is responsible for follow-up after critical illness? GP, ICU and patient perspectives | 4.1 | 1 | Citations (PDF) |
| 243 | Transplantation of mesenchymal stromal cell-derived mitochondria alleviates endothelial dysfunction in pre-clinical models of acute respiratory distress syndrome | 3.2 | 4 | Citations (PDF) |
| 244 | Co-enrolment in critical care trials: a secondary analysis of the RECOVERY-RS trial | 4.1 | 0 | Citations (PDF) |
| 245 | Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial | 0.5 | 3 | Citations (PDF) |
| 246 | The POETIC (PrOcess Evaluation of Trials In Critical care) Framework: A Structured Approach for Designing and Conducting Process Evaluations in Critical Care Trials 0, 7, e1355 | | 0 | Citations (PDF) |
| 247 | Time of day of cardiac surgery and postoperative outcomes in the
UK
: a secondary analysis of linked national datasets | 3.2 | 2 | Citations (PDF) |
| 248 | Interleukin-6 is a mediator of therapeutic efficacy in acute lung injury | 5.0 | 2 | Citations (PDF) |
| 249 | Optimizing endpoints in early phase clinical trials of acute respiratory distress syndrome | 5.0 | 0 | Citations (PDF) |
| 250 | Study into the Reversal of Septic Shock with Beta Blockade (Landiolol): the STRESS-L randomised trial | 0.0 | 0 | Citations (PDF) |
| 251 | Carbocisteine Reduces Airway Mucus Obstruction and Alters Inflammatory Cell Populations in a Model of Muco‐Obstructive Lung Disease | 2.0 | 0 | Citations (PDF) |
