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122 PR articles • 24,023 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Commentary in light of current findings on Roode et al., Developmental Biology (2012) Human hypoblast formation is not dependent on FGF signalling
Developmental Biology, 2024, 512, 11-12
1.91Citations (PDF)
2Branching topology of the human embryo transcriptome revealed by Entropy Sort Feature Weighting
Development (Cambridge), 2024, 151,
3.18Citations (PDF)
3Propagating pluripotency – The conundrum of self‐renewal
BioEssays, 2024, 46,
2.210Citations (PDF)
4Cell state transitions: catch them if you can
Development (Cambridge), 2023, 150,
3.15Citations (PDF)
5Epigenetic dynamics during capacitation of naïve human pluripotent stem cells
Science Advances, 2023, 9,
11.015Citations (PDF)
6NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation
Genes and Development, 2022, 36, 348-367
4.740Citations (PDF)
7Suppression of YAP safeguards human naïve pluripotency
Development (Cambridge), 2022, 149,
3.120Citations (PDF)
8Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
Cell Stem Cell, 2021, 28, 453-471.e8
16.8238Citations (PDF)
9Cooperative genetic networks drive embryonic stem cell transition from naïve to formative pluripotency
EMBO Journal, 2021, 40,
7.448Citations (PDF)
10Human naive epiblast cells possess unrestricted lineage potential
Cell Stem Cell, 2021, 28, 1040-1056.e6
16.8315Citations (PDF)
11Disabling de novo DNA methylation in embryonic stem cells allows an illegitimate fate trajectory
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118,
7.619Citations (PDF)
12Pluripotent stem cells related to embryonic disc exhibit common self-renewal requirements in diverse livestock species
Development (Cambridge), 2021, 148,
3.182Citations (PDF)
13GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells
Stem Cell Research and Therapy, 2020, 11,
6.99Citations (PDF)
14Microfluidic platform for 3D cell culture with live imaging and clone retrieval
Lab on A Chip, 2020, 20, 2580-2591
5.222Citations (PDF)
15Zfp281 orchestrates interconversion of pluripotent states by engaging Ehmt1 and Zic2
EMBO Journal, 2020, 39,
7.430Citations (PDF)
16In Vitro Recapitulation of Developmental Transitions in Human Neural Stem Cells
Stem Cells, 2019, 37, 1429-1440
3.310Citations (PDF)
17Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency
Stem Cell Reports, 2019, 13, 1083-1098
4.5107Citations (PDF)
18Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Cell Stem Cell, 2019, 25, 433-446.e7
16.872Citations (PDF)
19Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency
Cell Stem Cell, 2019, 24, 785-801.e7
16.8112Citations (PDF)
20Defined conditions for propagation and manipulation of mouse embryonic stem cells
Development (Cambridge), 2019, 146,
3.1123Citations (PDF)
21Capacitation of human naïve pluripotent stem cells for multi-lineage differentiation
Development (Cambridge), 2019, 146,
3.1122Citations (PDF)
22Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation
Small, 2019, 15,
11.643Citations (PDF)
23A common molecular logic determines embryonic stem cell self‐renewal and reprogramming
EMBO Journal, 2019, 38,
7.443Citations (PDF)
24Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast
Development (Cambridge), 2018, ,
3.1184Citations (PDF)
25Pluripotency Deconstructed
Development Growth and Differentiation, 2018, 60, 44-52
0.988Citations (PDF)
26Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development
Development (Cambridge), 2018, 145,
3.1222Citations (PDF)
27LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein
Journal of Cell Science, 2018, 131,
2.54Citations (PDF)
28Interplay of cell–cell contacts and RhoA/ <scp>MRTF</scp> ‐A signaling regulates cardiomyocyte identity
EMBO Journal, 2018, 37,
7.474Citations (PDF)
29Negative feedback via <scp>RSK</scp> modulates Erk‐dependent progression from naïve pluripotency
EMBO Reports, 2018, 19,
5.236Citations (PDF)
30Formative pluripotency: the executive phase in a developmental continuum
Development (Cambridge), 2017, 144, 365-373
3.1459Citations (PDF)
31Tracking the embryonic stem cell transition from ground state pluripotency
Development (Cambridge), 2017, 144, 1221-1234
3.1293Citations (PDF)
32Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters
Stem Cell Reports, 2017, 9, 1262-1274
4.513Citations (PDF)
33NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State
Stem Cell Reports, 2017, 9, 77-91
4.584Citations (PDF)
34Epigenetic resetting of human pluripotency
Development (Cambridge), 2017, 144, 2748-2763
3.1301Citations (PDF)
35A conceptual and computational framework for modelling and understanding the non-equilibrium gene regulatory networks of mouse embryonic stem cells
PLoS Computational Biology, 2017, 13, e1005713
3.17Citations (PDF)
36Stat3 promotes mitochondrial transcription and oxidative respiration during maintenance and induction of naive pluripotency
EMBO Journal, 2016, 35, 618-634
7.4177Citations (PDF)
37Convergence of cMyc and β‐catenin on Tcf7l1 enables endoderm specification
EMBO Journal, 2016, 35, 356-368
7.439Citations (PDF)
38Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
Cell, 2016, 164, 668-680
34.1261Citations (PDF)
39Dynamics of gene silencing during X inactivation using allele-specific RNA-seq
Genome Biology, 2015, 16,
8.2123Citations (PDF)
40Towards consistent generation of pancreatic lineage progenitors from human pluripotent stem cells
Philosophical Transactions of the Royal Society B: Biological Sciences, 2015, 370, 20140365
3.838Citations (PDF)
41Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis
Developmental Cell, 2015, 35, 366-382
7.8454Citations (PDF)
42A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs
PLoS ONE, 2014, 9, e92496
2.433Citations (PDF)
43Mapping the route from naive pluripotency to lineage specification
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014, 369, 20130540
3.8199Citations (PDF)
44Differentiation of Human Induced Pluripotent Stem Cells into Brown and White Adipocytes: Role of Pax3
Stem Cells, 2014, 32, 1459-1467
3.388Citations (PDF)
45The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification
Nature Cell Biology, 2014, 16, 513-525
16.9434Citations (PDF)
46Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human
Cell, 2014, 158, 1254-1269
34.1901Citations (PDF)
47Otx2 and Oct4 Drive Early Enhancer Activation during Embryonic Stem Cell Transition from Naive Pluripotency
Cell Reports, 2014, 7, 1968-1981
6.4135Citations (PDF)
48The Nature of Embryonic Stem Cells
Annual Review of Cell and Developmental Biology, 2014, 30, 647-675
9.6415Citations (PDF)
49Genetic Exploration of the Exit from Self-Renewal Using Haploid Embryonic Stem Cells
Cell Stem Cell, 2014, 14, 385-393
16.8193Citations (PDF)
50Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor
EMBO Journal, 2013, 32, 2561-2574
7.4214Citations (PDF)
51Neural Stem Cells Engrafted in the Adult Brain Fuse with Endogenous Neurons
Stem Cells and Development, 2013, 22, 538-547
2.024Citations (PDF)
52Naive pluripotency is associated with global DNA hypomethylation
Nature Structural and Molecular Biology, 2013, 20, 311-316
8.7515Citations (PDF)
53Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3
Cell, 2013, 153, 335-347
34.1325Citations (PDF)
54The mammalian germline as a pluripotency cycle
Development (Cambridge), 2013, 140, 2495-2501
3.163Citations (PDF)
55Rebuilding Pluripotency from Primordial Germ Cells
Stem Cell Reports, 2013, 1, 66-78
4.566Citations (PDF)
56Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
Genes and Development, 2013, 27, 654-669
4.7130Citations (PDF)
57Stem Cells Expanded from the Human Embryonic Hindbrain Stably Retain Regional Specification and High Neurogenic Potency
Journal of Neuroscience, 2013, 33, 12407-12422
3.782Citations (PDF)
58Automated Large-Scale Culture and Medium-Throughput Chemical Screen for Modulators of Proliferation and Viability of Human Induced Pluripotent Stem Cell–Derived Neuroepithelial-like Stem Cells
SLAS Discovery, 2013, 18, 258-268
2.542Citations (PDF)
59A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1
PLoS ONE, 2013, 8, e77053
2.460Citations (PDF)
60A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation
PLoS Genetics, 2012, 8, e1003112
3.378Citations (PDF)
61Germline potential of parthenogenetic haploid mouse embryonic stem cells
Development (Cambridge), 2012, 139, 3301-3305
3.176Citations (PDF)
62Pluripotency in the Embryo and in Culture
Cold Spring Harbor Perspectives in Biology, 2012, 4, a008128-a008128
7.3280Citations (PDF)
63JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency
Nature Communications, 2012, 3,
13.9108Citations (PDF)
64Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid
Neuroscience Research, 2012, 72, 23-31
2.139Citations (PDF)
65The Transcriptional and Epigenomic Foundations of Ground State Pluripotency
Cell, 2012, 149, 590-604
34.1830Citations (PDF)
66Capture of Neuroepithelial-Like Stem Cells from Pluripotent Stem Cells Provides a Versatile System for In Vitro Production of Human Neurons
PLoS ONE, 2012, 7, e29597
2.4289Citations (PDF)
67Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal
Cell Stem Cell, 2012, 11, 491-504
16.8370Citations (PDF)
68Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human Induced Pluripotent Stem Cell-Derived Long-Term Self-Renewing Neuroepithelial-Like Stem Cells
Stem Cells, 2012, 30, 1163-1173
3.3223Citations (PDF)
69Self-organizing circuitry and emergent computation in mouse embryonic stem cells
Stem Cell Research, 2012, 8, 324-333
0.621Citations (PDF)
70The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
Neurobiology of Disease, 2012, 46, 41-51
5.2166Citations (PDF)
71Human hypoblast formation is not dependent on FGF signalling
Developmental Biology, 2012, 361, 358-363
1.9232Citations (PDF)
72Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells
Journal of Cell Science, 2011, 124, 1867-1877
2.562Citations (PDF)
73The origin and identity of embryonic stem cells
Development (Cambridge), 2011, 138, 3-8
3.1194Citations (PDF)
74Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells <i>In vitro</i>
Glia, 2011, 59, 1588-1599
5.169Citations (PDF)
75The Liberation of Embryonic Stem Cells
PLoS Genetics, 2011, 7, e1002019
3.388Citations (PDF)
76A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
PLoS ONE, 2011, 6, e18189
2.462Citations (PDF)
77A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency
Development (Cambridge), 2010, 137, 3185-3192
3.1154Citations (PDF)
78Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
Development (Cambridge), 2010, 137, 2279-2287
3.1142Citations (PDF)
79Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos
Development (Cambridge), 2010, 137, 693-704
3.172Citations (PDF)
80Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
Cell Stem Cell, 2010, 7, 319-328
16.8228Citations (PDF)
81CD133 (Prominin) Negative Human Neural Stem Cells Are Clonogenic and Tripotent
PLoS ONE, 2009, 4, e5498
2.4120Citations (PDF)
82Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
Development (Cambridge), 2009, 136, 3215-3222
3.1571Citations (PDF)
83Nanog Is the Gateway to the Pluripotent Ground State
Cell, 2009, 138, 722-737
34.1955Citations (PDF)
84Glioma Stem Cell Lines Expanded in Adherent Culture Have Tumor-Specific Phenotypes and Are Suitable for Chemical and Genetic Screens
Cell Stem Cell, 2009, 4, 568-580
16.8953Citations (PDF)
85Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal
Cell Stem Cell, 2009, 5, 597-609
16.8355Citations (PDF)
86Parameters influencing derivation of embryonic stem cells from murine embryos
Genesis, 2008, 46, 758-767
2.792Citations (PDF)
87Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition
PLoS Biology, 2008, 6, e253
5.0765Citations (PDF)
88Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture
Molecular and Cellular Neurosciences, 2008, 38, 245-258
2.2213Citations (PDF)
89Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation
Molecular and Cellular Neurosciences, 2008, 38, 393-403
2.262Citations (PDF)
90Capture of Authentic Embryonic Stem Cells from Rat Blastocysts
Cell, 2008, 135, 1287-1298
34.1748Citations (PDF)
91Neuroepithelial Cells Supply an Initial Transient Wave of MSC Differentiation
Cell, 2007, 129, 1377-1388
34.1513Citations (PDF)
92Essential Alterations of Heparan Sulfate During the Differentiation of Embryonic Stem Cells to Sox1-Enhanced Green Fluorescent Protein-Expressing Neural Progenitor Cells
Stem Cells, 2007, 25, 1913-1923
3.3134Citations (PDF)
93Tripotential Differentiation of Adherently Expandable Neural Stem (NS) Cells
PLoS ONE, 2007, 2, e298
2.499Citations (PDF)
94Reprogramming Efficiency Following Somatic Cell Nuclear Transfer Is Influenced by the Differentiation and Methylation State of the Donor Nucleus
Stem Cells, 2006, 24, 2007-2013
3.3254Citations (PDF)
95Exploitation of adherent neural stem cells in basic and applied neurobiology
Regenerative Medicine, 2006, 1, 111-118
2.028Citations (PDF)
96Notch Promotes Neural Lineage Entry by Pluripotent Embryonic Stem Cells
PLoS Biology, 2006, 4, e121
5.0239Citations (PDF)
97Adherent Neural Stem (NS) Cells from Fetal and Adult Forebrain
Cerebral Cortex, 2006, 16, i112-i120
2.8238Citations (PDF)
98Unequal segregation of parental chromosomes in embryonic stem cell hybrids
Molecular Reproduction and Development, 2005, 71, 305-314
2.937Citations (PDF)
99Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell
PLoS Biology, 2005, 3, e283
5.0794Citations (PDF)
100Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors
Bone, 2005, 36, 758-769
3.6248Citations (PDF)
101Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice
Developmental Biology, 2005, 281, 1-21
1.989Citations (PDF)
102Self-renewal of teratocarcinoma and embryonic stem cells
Oncogene, 2004, 23, 7150-7160
6.7499Citations (PDF)
103SoxB transcription factors specify neuroectodermal lineage choice in ES cells
Molecular and Cellular Neurosciences, 2004, 27, 332-342
2.2123Citations (PDF)
104An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis
Chromosoma, 2003, 112, 183-189
2.011Citations (PDF)
105Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells
Cell, 2003, 113, 643-655
34.13,018Citations (PDF)
106BMP Induction of Id Proteins Suppresses Differentiation and Sustains Embryonic Stem Cell Self-Renewal in Collaboration with STAT3
Cell, 2003, 115, 281-292
34.11,990Citations (PDF)
107Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from <i>Sox1</i> - <i>gfp</i> knock-in mice
Proceedings of the National Academy of Sciences of the United States of America, 2003, 100, 11836-11841
7.6238Citations (PDF)
108Genesis of embryonic stem cells
Philosophical Transactions of the Royal Society B: Biological Sciences, 2003, 358, 1397-1402
3.8109Citations (PDF)
109Rapid Loss of Oct-4 and Pluripotency in Cultured Rodent Blastocysts and Derivative Cell Lines1
Biology of Reproduction, 2003, 68, 222-229
2.6143Citations (PDF)
110Normal timing of oligodendrocyte development from genetically engineered,lineage-selectable mouse ES cells
Journal of Cell Science, 2002, 115, 3657-3665
2.5123Citations (PDF)
111Signalling, cell cycle and pluripotency in embryonic stem cells
Trends in Cell Biology, 2002, 12, 432-438
12.3672Citations (PDF)
112Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation
Nature Biotechnology, 2002, 20, 1240-1245
32.2309Citations (PDF)
113Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines
Development (Cambridge), 2001, 128, 2333-2339
3.1245Citations (PDF)
114Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells
Developmental Biology, 1999, 210, 30-43
1.9531Citations (PDF)
115Cell therapy: In search of pluripotency
Current Biology, 1998, 8, R802-R804
3.648Citations (PDF)
116Generation of purified neural precursors from embryonic stem cells by lineage selection
Current Biology, 1998, 8, 971-S2
3.6450Citations (PDF)
117Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4
Cell, 1998, 95, 379-391
34.13,135Citations (PDF)
118Paracrine Induction of Stem Cell Renewal by LIF-Deficient Cells: A New ES Cell Regulatory Pathway
Developmental Biology, 1998, 203, 149-162
1.9111Citations (PDF)
119Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis
Mechanisms of Development, 1996, 57, 123-131
2.6133Citations (PDF)
120Derivation of Germline Competent Embryonic Stem Cells with a Combination of Interleukin-6 and Soluble Interleukin-6 Receptor
Experimental Cell Research, 1994, 215, 237-239
3.281Citations (PDF)
121Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways
Mechanisms of Development, 1994, 45, 163-171
2.6201Citations (PDF)
122A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation
ELife, 0, 6,
1.643Citations (PDF)