| 1 | Mammalian DNA ligases; roles in maintaining genome integrity | 4.2 | 18 | Citations (PDF) |
| 2 | FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease | 13.9 | 29 | Citations (PDF) |
| 3 | Redundant but essential functions of PARP1 and PARP2 in DNA ligase I-independent DNA replication | 15.8 | 4 | Citations (PDF) |
| 4 | The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions | 15.8 | 20 | Citations (PDF) |
| 5 | Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase | 3.9 | 12 | Citations (PDF) |
| 6 | Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers | 11.5 | 22 | Citations (PDF) |
| 7 | Structural basis of long-range to short-range synaptic transition in NHEJ | 39.5 | 143 | Citations (PDF) |
| 8 | Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus | 2.3 | 12 | Citations (PDF) |
| 9 | An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex | 15.8 | 31 | Citations (PDF) |
| 10 | Altered DNA ligase activity in human disease | 5.3 | 32 | Citations (PDF) |
| 11 | Human DNA ligases in replication and repair | 2.6 | 48 | Citations (PDF) |
| 12 | XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells | 2.9 | 48 | Citations (PDF) |
| 13 | Dynamic DNA-bound PCNA complexes co-ordinate Okazaki fragment synthesis, processing and ligation | 4.2 | 20 | Citations (PDF) |
| 14 | NAD+ is not utilized as a co-factor for DNA ligation by human DNA ligase IV | 15.8 | 4 | Citations (PDF) |
| 15 | 1HN, 13C, and 15N backbone resonance assignments of the human DNA ligase 3 DNA-binding domain (residues 257-477) | 0.7 | 2 | Citations (PDF) |
| 16 | Repair of DNA double-strand breaks by mammalian alternative end-joining pathways | 2.3 | 205 | Citations (PDF) |
| 17 | Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis | 13.9 | 191 | Citations (PDF) |
| 18 | The SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast | 15.8 | 34 | Citations (PDF) |
| 19 | The Human Ligase IIIα-XRCC1 Protein Complex Performs DNA Nick Repair after Transient Unwrapping of Nucleosomal DNA | 2.3 | 38 | Citations (PDF) |
| 20 | Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor | 2.6 | 23 | Citations (PDF) |
| 21 | SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV | 2.6 | 64 | Citations (PDF) |
| 22 | Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex | 2.3 | 29 | Citations (PDF) |
| 23 | Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1–Dependent Apoptosis in Cancer Cells | 0.6 | 24 | Citations (PDF) |
| 24 | An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex | 2.3 | 70 | Citations (PDF) |
| 25 | Synthesis and structure determination of SCR7, a DNA ligase inhibitor | 1.3 | 6 | Citations (PDF) |
| 26 | Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks | 2.6 | 26 | Citations (PDF) |
| 27 | Aromatase Inhibitor–Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer | 1.8 | 17 | Citations (PDF) |
| 28 | Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining | 15.8 | 28 | Citations (PDF) |
| 29 | The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome | 2.3 | 47 | Citations (PDF) |
| 30 | Role of the yeast DNA repair protein Nej1 in end processing during the repair of DNA double strand breaks by non-homologous end joining | 2.6 | 16 | Citations (PDF) |
| 31 | Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells | 1.3 | 2 | Citations (PDF) |
| 32 | Ubiquitin-specific Peptidase 20 Regulates Rad17 Stability, Checkpoint Kinase 1 Phosphorylation and DNA Repair by Homologous Recombination | 2.3 | 31 | Citations (PDF) |
| 33 | Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining | 13.7 | 312 | Citations (PDF) |
| 34 | Structure and function of the DNA ligases encoded by the mammalian LIG3 gene | 2.4 | 58 | Citations (PDF) |
| 35 | Phosphorylation of Serine 51 Regulates the Interaction of Human DNA Ligase I with Replication Factor C and Its Participation in DNA Replication and Repair | 2.3 | 15 | Citations (PDF) |
| 36 | The Interaction between Polynucleotide Kinase Phosphatase and the DNA Repair Protein XRCC1 Is Critical for Repair of DNA Alkylation Damage and Stable Association at DNA Damage Sites | 2.3 | 31 | Citations (PDF) |
| 37 | Targeting Abnormal DNA Repair in Therapy-Resistant Breast Cancers | 3.5 | 87 | Citations (PDF) |
| 38 | A High-Throughput Scintillation Proximity-Based Assay for Human DNA Ligase IV | 1.5 | 15 | Citations (PDF) |
| 39 | The Nucleotide Sequence, DNA Damage Location, and Protein Stoichiometry Influence the Base Excision Repair Outcome at CAG/CTG Repeats | 2.8 | 39 | Citations (PDF) |
| 40 | Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway | 2.3 | 130 | Citations (PDF) |
| 41 | Yeast Nej1 Is a Key Participant in the Initial End Binding and Final Ligation Steps of Nonhomologous End Joining | 2.3 | 44 | Citations (PDF) |
| 42 | Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States | 2.8 | 100 | Citations (PDF) |
| 43 | Phosphorylation of Human DNA Ligase I Regulates Its Interaction with Replication Factor C and Its Participation in DNA Replication and DNA Repair | 2.5 | 29 | Citations (PDF) |
| 44 | CTG/CAG Repeat Instability Is Modulated by the Levels of Human DNA Ligase I and Its Interaction with Proliferating Cell Nuclear Antigen | 2.3 | 37 | Citations (PDF) |
| 45 | The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1 | 2.6 | 26 | Citations (PDF) |
| 46 | Distinct kinetics of human DNA ligases I, IIIα, IIIβ, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair | 2.6 | 28 | Citations (PDF) |
| 47 | Eukaryotic DNA Ligases: Structural and Functional Insights | 17.8 | 314 | Citations (PDF) |
| 48 | Identification and Validation of Human DNA Ligase Inhibitors Using Computer-Aided Drug Design | 6.7 | 78 | Citations (PDF) |
| 49 | Two DNA-binding and Nick Recognition Modules in Human DNA Ligase III | 2.3 | 55 | Citations (PDF) |
| 50 | Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair | 0.6 | 165 | Citations (PDF) |
| 51 | Up-regulation of WRN and DNA ligase IIIα in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksBlood, 2008, 112, 1413-1423 | 4.2 | 142 | Citations (PDF) |
| 52 | A Conserved Physical and Functional Interaction between the Cell Cycle Checkpoint Clamp Loader and DNA Ligase I of Eukaryotes | 2.3 | 20 | Citations (PDF) |
| 53 | Role of Dnl4–Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination | 8.7 | 121 | Citations (PDF) |
| 54 | NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells | 2.6 | 135 | Citations (PDF) |
| 55 | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA | 13.7 | 149 | Citations (PDF) |
| 56 | Genetic Instability Induced by Overexpression of DNA Ligase I in Budding Yeast | 4.2 | 37 | Citations (PDF) |
| 57 | Translocation of XRCC1 and DNA ligase III from centrosomes to chromosomes in response to DNA damage in mitotic human cells | 15.8 | 51 | Citations (PDF) |
| 58 | Mechanism of DNA double-strand break repair by non-homologous end joining | 2.6 | 272 | Citations (PDF) |
| 59 | Reduced repair of DNA double-strand breaks by homologous recombination in a DNA ligase I-deficient human cell line | 2.6 | 30 | Citations (PDF) |
| 60 | Processing and Joining of DNA Ends Coordinated by Interactions among Dnl4/Lif1, Pol4, and FEN-1 | 2.3 | 49 | Citations (PDF) |
| 61 | XRCC1 co-localizes and physically interacts with PCNA | 15.8 | 179 | Citations (PDF) |
| 62 | A Conserved Interaction between the Replicative Clamp Loader and DNA Ligase in Eukaryotes | 2.3 | 53 | Citations (PDF) |
| 63 | Physical and Functional Interaction between the XPF/ERCC1 Endonuclease and hRad52 | 2.3 | 92 | Citations (PDF) |
| 64 | Human DNA ligase I completely encircles and partially unwinds nicked DNA | 39.5 | 323 | Citations (PDF) |
| 65 | AP Endonuclease-Independent DNA Base Excision Repair in Human Cells | 13.7 | 457 | Citations (PDF) |
| 66 | Physical and Functional Interaction between DNA Ligase IIIα and Poly(ADP-Ribose) Polymerase 1 in DNA Single-Strand Break Repair | 2.5 | 220 | Citations (PDF) |
| 67 | A Physical and Functional Interaction between Yeast Pol4 and Dnl4-Lif1 Links DNA Synthesis and Ligation in Nonhomologous End Joining | 2.3 | 101 | Citations (PDF) |
| 68 | Promotion of Dnl4-Catalyzed DNA End-Joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 Complexes | 13.7 | 281 | Citations (PDF) |
| 69 | Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair | 3.7 | 230 | Citations (PDF) |
| 70 | Interactions of the DNA Ligase IV-XRCC4 Complex with DNA Ends and the DNA-dependent Protein Kinase | 2.3 | 195 | Citations (PDF) |
| 71 | DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase | 2.3 | 95 | Citations (PDF) |
| 72 | Thermodynamics of Human DNA Ligase I Trimerization and Association with DNA Polymerase β | 2.3 | 72 | Citations (PDF) |
| 73 | Specific Interaction of DNA Polymerase β and DNA Ligase I in a Multiprotein Base Excision Repair Complex from Bovine Testis | 2.3 | 245 | Citations (PDF) |
| 74 | Purification and Characterization of DNA Ligase III from Bovine Testes | 2.3 | 69 | Citations (PDF) |
| 75 | Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents | 34.4 | 279 | Citations (PDF) |