| 1 | How the JCI’s most-cited paper sparked the field of lipoprotein research | 10.6 | 1 | Citations (PDF) |
| 2 | Phosphorylation of Insig-2 mediates inhibition of fatty acid synthesis by polyunsaturated fatty acids | 7.5 | 11 | Citations (PDF) |
| 3 | Akira Endo, who discovered a “penicillin” for heart attacks (1933 to 2024) | 7.5 | 0 | Citations (PDF) |
| 4 | Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol | 7.5 | 40 | Citations (PDF) |
| 5 | Unexpected role for IGF-1 in starvation: Maintenance of blood glucose | 7.5 | 28 | Citations (PDF) |
| 6 | Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensingCell, 2021, 184, 3689-3701.e22 | 33.6 | 38 | Citations (PDF) |
| 7 | Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine | 7.5 | 132 | Citations (PDF) |
| 8 | Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice | 7.5 | 40 | Citations (PDF) |
| 9 | Retrospective on Cholesterol Homeostasis: The Central Role of Scap | 17.4 | 476 | Citations (PDF) |
| 10 | Cholesterol-induced conformational changes in the sterol-sensing domain of the Scap protein suggest feedback mechanism to control cholesterol synthesis | 2.2 | 38 | Citations (PDF) |
| 11 | Triazoles inhibit cholesterol export from lysosomes by binding to NPC1 | 7.5 | 70 | Citations (PDF) |
| 12 | Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex | 7.5 | 77 | Citations (PDF) |
| 13 | Direct Demonstration That Loop1 of Scap Binds to Loop7 | 2.2 | 19 | Citations (PDF) |
| 14 | Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone | 7.5 | 73 | Citations (PDF) |
| 15 | A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins | 33.6 | 1,127 | Citations (PDF) |
| 16 | Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet | 25.2 | 146 | Citations (PDF) |
| 17 | Use of mutant
125
I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells | 7.5 | 121 | Citations (PDF) |
| 18 | Point Mutation in Luminal Loop 7 of Scap Protein Blocks Interaction with Loop 1 and Abolishes Movement to Golgi | 2.2 | 29 | Citations (PDF) |
| 19 | Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase | 7.5 | 265 | Citations (PDF) |
| 20 | Profound Hypoglycemia in Starved, Ghrelin-deficient Mice Is Caused by Decreased Gluconeogenesis and Reversed by Lactate or Fatty Acids | 2.2 | 119 | Citations (PDF) |
| 21 | Scientific Side Trips: Six Excursions from the Beaten Path | 2.2 | 7 | Citations (PDF) |
| 22 | The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals | 25.2 | 304 | Citations (PDF) |
| 23 | Surviving Starvation: Essential Role of the Ghrelin-Growth Hormone Axis | 1.6 | 108 | Citations (PDF) |
| 24 | Identification of Luminal Loop 1 of Scap Protein as the Sterol Sensor That Maintains Cholesterol Homeostasis | 2.2 | 87 | Citations (PDF) |
| 25 | Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice | 7.5 | 44 | Citations (PDF) |
| 26 | Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin | 2.3 | 53 | Citations (PDF) |
| 27 | Ghrelin secretion stimulated by β
1
-adrenergic receptors in cultured ghrelinoma cells and in fasted mice | 7.5 | 186 | Citations (PDF) |
| 28 | Ghrelin
O
-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice | 7.5 | 412 | Citations (PDF) |
| 29 | LXR-SREBP-1c-Phospholipid Transfer Protein Axis Controls Very Low Density Lipoprotein (VLDL) Particle Size | 2.2 | 90 | Citations (PDF) |
| 30 | Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis | 7.5 | 682 | Citations (PDF) |
| 31 | Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes | 25.2 | 218 | Citations (PDF) |
| 32 | Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells | 7.5 | 172 | Citations (PDF) |
| 33 | Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice | 2.2 | 62 | Citations (PDF) |
| 34 | Regulated Endoplasmic Reticulum-associated Degradation of a Polytopic Protein | 2.2 | 35 | Citations (PDF) |
| 35 | Familial Hypercholesterolemia: Defective Binding of Lipoproteins to Cultured Fibroblasts Associated with Impaired Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity | 5.6 | 0 | Citations (PDF) |
| 36 | The LDL Receptor | 6.0 | 1,250 | Citations (PDF) |
| 37 | Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of CholesterolCell, 2009, 137, 1213-1224 | 33.6 | 649 | Citations (PDF) |
| 38 | Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone | 33.6 | 1,122 | Citations (PDF) |
| 39 | Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance | 25.2 | 536 | Citations (PDF) |
| 40 | Purified NPC1 Protein | 2.2 | 206 | Citations (PDF) |
| 41 | Purified NPC1 Protein | 2.2 | 215 | Citations (PDF) |
| 42 | NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes | 7.5 | 462 | Citations (PDF) |
| 43 | Inhibition of ghrelin
O
-acyltransferase (GOAT) by octanoylated pentapeptides | 7.5 | 186 | Citations (PDF) |
| 44 | From fatty streak to fatty liver: 33 years of joint publications in the JCI | 10.6 | 33 | Citations (PDF) |
| 45 | Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig | 7.5 | 552 | Citations (PDF) |
| 46 | Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins | 7.5 | 276 | Citations (PDF) |
| 47 | The Central Role of Insig Proteins in Regulating Cholesterol Homeostasis | 0.6 | 0 | Citations (PDF) |
| 48 | Protein Sensors for Membrane Sterols | 33.6 | 1,581 | Citations (PDF) |
| 49 | Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake | 25.2 | 243 | Citations (PDF) |
| 50 | Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis | 7.5 | 51 | Citations (PDF) |
| 51 | Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin | 10.6 | 77 | Citations (PDF) |
| 52 | Insig Required for Sterol-mediated Inhibition of Scap/SREBP Binding to COPII Proteins in Vitro*♦ | 2.2 | 225 | Citations (PDF) |
| 53 | Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change | 7.5 | 44 | Citations (PDF) |
| 54 | Identification of FBL2 As a Geranylgeranylated Cellular Protein Required for Hepatitis C Virus RNA Replication | 13.3 | 276 | Citations (PDF) |
| 55 | Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver | 25.2 | 64 | Citations (PDF) |
| 56 | Schoenheimer effect explained - feedback regulation of cholesterol synthesis in mice mediated by Insig proteins | 10.6 | 200 | Citations (PDF) |
| 57 | Membrane Topology of Human Insig-1, a Protein Regulator of Lipid Synthesis | 2.2 | 91 | Citations (PDF) |
| 58 | Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver | 7.5 | 505 | Citations (PDF) |
| 59 | Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs | 2.2 | 419 | Citations (PDF) |
| 60 | The effect of natal experience on habitat preferences | 6.3 | 474 | Citations (PDF) |
| 61 | Direct Binding of Cholesterol to the Purified Membrane Region of SCAP | 13.3 | 315 | Citations (PDF) |
| 62 | A tribute to Akira Endo, discoverer of a “Penicillin” for cholesterol | 3.1 | 45 | Citations (PDF) |
| 63 | LOWERING PLASMA CHOLESTEROL BY RAISING LDL RECEPTORS | 3.1 | 18 | Citations (PDF) |
| 64 | Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholeserolemia heterozygotes | 3.1 | 7 | Citations (PDF) |
| 65 | Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis | 10.6 | 49 | Citations (PDF) |
| 66 | Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis | 10.6 | 242 | Citations (PDF) |
| 67 | Accelerated Degradation of HMG CoA Reductase Mediated by Binding of Insig-1 to Its Sterol-Sensing Domain | 13.3 | 344 | Citations (PDF) |
| 68 | Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes | 7.5 | 1,345 | Citations (PDF) |
| 69 | Reconstitution of Sterol-regulated Endoplasmic Reticulum-to-Golgi Transport of SREBP-2 in Insect Cells by Co-expression of Mammalian SCAP and Insigs | 2.2 | 36 | Citations (PDF) |
| 70 | Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles | 7.5 | 101 | Citations (PDF) |
| 71 | Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation | 7.5 | 352 | Citations (PDF) |
| 72 | Liver-specific mRNA for Insig-2 down-regulated by insulin: Implications for fatty acid synthesis | 7.5 | 274 | Citations (PDF) |
| 73 | Insig-dependent Ubiquitination and Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-CoA Reductase Stimulated by Sterols and Geranylgeraniol | 2.2 | 278 | Citations (PDF) |
| 74 | Characterization of Mouse Short-chain Aldehyde Reductase (SCALD), an Enzyme Regulated by Sterol Regulatory Element-binding Proteins | 2.2 | 51 | Citations (PDF) |
| 75 | Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins | 7.5 | 502 | Citations (PDF) |
| 76 | Regulation of SREBP Processing and Membrane Lipid Production by Phospholipids in Drosophila | 36.2 | 311 | Citations (PDF) |
| 77 | Mutant Mammalian Cells as Tools to Delineate the Sterol Regulatory Element-Binding Protein Pathway for Feedback Regulation of Lipid Synthesis | 2.8 | 223 | Citations (PDF) |
| 78 | Diminished Hepatic Response to Fasting/Refeeding and Liver X Receptor Agonists in Mice with Selective Deficiency of Sterol Regulatory Element-binding Protein-1c | 2.2 | 601 | Citations (PDF) |
| 79 | Crucial Step in Cholesterol Homeostasis | 33.6 | 937 | Citations (PDF) |
| 80 | Cholesterol Addition to ER Membranes Alters Conformation of SCAP, the SREBP Escort Protein that Regulates Cholesterol Metabolism | 13.3 | 382 | Citations (PDF) |
| 81 | The SREBP Pathway in Drosophila | 7.7 | 188 | Citations (PDF) |
| 82 | Structure of the LDL Receptor Extracellular Domain at Endosomal pH | 36.2 | 459 | Citations (PDF) |
| 83 | Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR | 7.5 | 437 | Citations (PDF) |
| 84 | Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands | 7.5 | 228 | Citations (PDF) |
| 85 | SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation | 4.6 | 305 | Citations (PDF) |
| 86 | Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene | 7.5 | 230 | Citations (PDF) |
| 87 | Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes | 7.5 | 103 | Citations (PDF) |
| 88 | Unsaturated Fatty Acids Down-regulate SREBP Isoforms 1a and 1c by Two Mechanisms in HEK-293 Cells | 2.2 | 408 | Citations (PDF) |
| 89 | Overexpression of Membrane Domain of SCAP Prevents Sterols from Inhibiting SCAP·SREBP Exit from Endoplasmic Reticulum | 2.2 | 77 | Citations (PDF) |
| 90 | Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by Site-2 protease | 7.5 | 139 | Citations (PDF) |
| 91 | Molecular Characterization of Human Acetyl-CoA Synthetase, an Enzyme Regulated by Sterol Regulatory Element-binding Proteins | 2.2 | 254 | Citations (PDF) |
| 92 | Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ | 4.6 | 1,576 | Citations (PDF) |
| 93 | Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice | 13.3 | 777 | Citations (PDF) |
| 94 | ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs | 13.3 | 1,767 | Citations (PDF) |
| 95 | Regulated Step in Cholesterol Feedback Localized to Budding of SCAP from ER Membranes | 33.6 | 326 | Citations (PDF) |
| 96 | Regulated Intramembrane Proteolysis | 33.6 | 1,322 | Citations (PDF) |
| 97 | Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice | 13.3 | 229 | Citations (PDF) |
| 98 | Presentation of the Kober Medal for 1999 to Jean D. Wilson Physician‐Scientist Exemplar | 3.0 | 1 | Citations (PDF) |
| 99 | Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes | 7.5 | 716 | Citations (PDF) |
| 100 | Membrane Topology of S2P, a Protein Required for Intramembranous Cleavage of Sterol Regulatory Element-binding Proteins | 2.2 | 108 | Citations (PDF) |
| 101 | Autocatalytic Processing of Site-1 Protease Removes Propeptide and Permits Cleavage of Sterol Regulatory Element-binding Proteins | 2.2 | 168 | Citations (PDF) |
| 102 | Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi | 7.5 | 228 | Citations (PDF) |
| 103 | A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood | 7.5 | 1,243 | Citations (PDF) |
| 104 | Secreted Site-1 Protease Cleaves Peptides Corresponding to Luminal Loop of Sterol Regulatory Element-binding Proteins | 2.2 | 69 | Citations (PDF) |
| 105 | Failure to Cleave Sterol Regulatory Element-binding Proteins (SREBPs) Causes Cholesterol Auxotrophy in Chinese Hamster Ovary Cells with Genetic Absence of SREBP Cleavage-activating Protein | 2.2 | 162 | Citations (PDF) |
| 106 | Burgers, Chips, and Genes | 4.0 | 1 | Citations (PDF) |
| 107 | Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy | 37.9 | 986 | Citations (PDF) |
| 108 | Transport-Dependent Proteolysis of SREBP | 33.6 | 311 | Citations (PDF) |
| 109 | Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL | 10.6 | 178 | Citations (PDF) |
| 110 | Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells | 13.3 | 391 | Citations (PDF) |
| 111 | Cleavage of Sterol Regulatory Element-binding Proteins (SREBPs) at Site-1 Requires Interaction with SREBP Cleavage-activating Protein | 2.2 | 206 | Citations (PDF) |
| 112 | Differential Stimulation of Cholesterol and Unsaturated Fatty Acid Biosynthesis in Cells Expressing Individual Nuclear Sterol Regulatory Element-binding Proteins | 2.2 | 208 | Citations (PDF) |
| 113 | Isolation of Cholesterol-requiring Mutant Chinese Hamster Ovary Cells with Defects in Cleavage of Sterol Regulatory Element-binding Proteins at Site 1 | 2.2 | 87 | Citations (PDF) |
| 114 | Second-site Cleavage in Sterol Regulatory Element-binding Protein Occurs at Transmembrane Junction as Determined by Cysteine Panning | 2.2 | 139 | Citations (PDF) |
| 115 | Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N | 7.5 | 128 | Citations (PDF) |
| 116 | Topology of SREBP Cleavage-activating Protein, a Polytopic Membrane Protein with a Sterol-sensing Domain | 2.2 | 179 | Citations (PDF) |
| 117 | Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy | 4.6 | 733 | Citations (PDF) |
| 118 | Sterol Regulatory Element Binding Proteins (SREBPs): Controllers of Lipid Synthesis and Cellular Uptake | 5.6 | 94 | Citations (PDF) |
| 119 | Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2. | 10.6 | 639 | Citations (PDF) |
| 120 | Cleavage Site for Sterol-regulated Protease Localized to a Leu-Ser Bond in the Lumenal Loop of Sterol Regulatory Element-binding Protein-2 | 2.2 | 162 | Citations (PDF) |
| 121 | Identification of Complexes between the COOH-terminal Domains of Sterol Regulatory Element-binding Proteins (SREBPs) and SREBP Cleavage-Activating Protein | 2.2 | 211 | Citations (PDF) |
| 122 | Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1 | 7.5 | 117 | Citations (PDF) |
| 123 | Complementation Cloning of S2P, a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs | 13.3 | 458 | Citations (PDF) |
| 124 | The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor | 33.6 | 3,606 | Citations (PDF) |
| 125 | Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver | 7.5 | 141 | Citations (PDF) |
| 126 | Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. | 10.6 | 700 | Citations (PDF) |
| 127 | Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. | 10.6 | 768 | Citations (PDF) |
| 128 | Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene. | 10.6 | 415 | Citations (PDF) |
| 129 | Sterol-Regulated Release of SREBP-2 from Cell Membranes Requires Two Sequential Cleavages, One Within a Transmembrane SegmentCell, 1996, 85, 1037-1046 | 33.6 | 520 | Citations (PDF) |
| 130 | Sterol Resistance in CHO Cells Traced to Point Mutation in SREBP Cleavage–Activating Protein | 33.6 | 466 | Citations (PDF) |
| 131 | Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. | 10.6 | 776 | Citations (PDF) |
| 132 | Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines | 7.5 | 55 | Citations (PDF) |
| 133 | Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis. | 7.3 | 293 | Citations (PDF) |
| 134 | Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells. | 7.5 | 161 | Citations (PDF) |
| 135 | Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins. | 7.5 | 70 | Citations (PDF) |
| 136 | Complementation of Mutation in Acyl-CoA:Cholesterol Acyltransferase (ACAT) Fails to Restore Sterol Regulation in ACAT-defective Sterol-resistant Hamster Cells | 2.2 | 50 | Citations (PDF) |
| 137 | Regulated Cleavage of Sterol Regulatory Element Binding Proteins Requires Sequences on Both Sides of the Endoplasmic Reticulum Membrane | 2.2 | 195 | Citations (PDF) |
| 138 | Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. | 7.5 | 299 | Citations (PDF) |
| 139 | Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. | 7.5 | 248 | Citations (PDF) |
| 140 | Polylysine and CVIM Sequences of K-RasB Dictate Specificity of Prenylation and Confer Resistance to Benzodiazepine Peptidomimetic in Vitro | 2.2 | 255 | Citations (PDF) |
| 141 | Hairpin Orientation of Sterol Regulatory Element-binding Protein-2 in Cell Membranes as Determined by Protease Protection | 2.2 | 141 | Citations (PDF) |
| 142 | CAAX Geranylgeranyl Transferase Transfers Farnesyl as Efficiently as Geranylgeranyl to RhoB | 2.2 | 138 | Citations (PDF) |
| 143 | cDNA Cloning of MCT2, a Second Monocarboxylate Transporter Expressed in Different Cells than MCT1 | 2.2 | 325 | Citations (PDF) |
| 144 | Three Different Rearrangements in a Single Intron Truncate Sterol Regulatory Element Binding Protein-2 and Produce Sterol-resistant Phenotype in Three Cell Lines | 2.2 | 92 | Citations (PDF) |
| 145 | Purification of an Interleukin-1β Converting Enzyme-related Cysteine Protease That Cleaves Sterol Regulatory Element-binding Proteins between the Leucine Zipper and Transmembrane Domains | 2.2 | 134 | Citations (PDF) |
| 146 | Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13 | 2.8 | 271 | Citations (PDF) |
| 147 | Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2. | 4.6 | 99 | Citations (PDF) |
| 148 | Gene therapy for cholesterol | 25.2 | 41 | Citations (PDF) |
| 149 | SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis | 33.6 | 991 | Citations (PDF) |
| 150 | Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: Implications for the Cori cycle | 33.6 | 571 | Citations (PDF) |
| 151 | The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. | 7.5 | 406 | Citations (PDF) |
| 152 | Benzodiazepine peptidomimetic BZA-5B interrupts the MAP kinase activation pathway in H-Ras-transformed Rat-1 cells, but not in untransformed cells. | 2.2 | 97 | Citations (PDF) |
| 153 | Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. | 10.6 | 657 | Citations (PDF) |
| 154 | cDNA Cloning of the Two Subunits of Human CAAX Farnesyltransferase and Chromosomal Mapping of FNTA and FNTB Loci and Related Sequences | 2.8 | 24 | Citations (PDF) |
| 155 | cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort proteinCell, 1993, 73, 1091-1099 | 33.6 | 332 | Citations (PDF) |
| 156 | SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene | 33.6 | 886 | Citations (PDF) |
| 157 | SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. | 7.5 | 603 | Citations (PDF) |
| 158 | Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion. | 7.5 | 165 | Citations (PDF) |
| 159 | SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene | 33.6 | 261 | Citations (PDF) |
| 160 | Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. | 10.6 | 1,480 | Citations (PDF) |
| 161 | Cytoplasmic sequence required for basolateral targeting of LDL receptor in livers of transgenic mice | 5.4 | 89 | Citations (PDF) |
| 162 | Purification of component A of Rab geranylgeranyl transferase: Possible identity with the choroideremia gene productCell, 1992, 70, 1049-1057 | 33.6 | 302 | Citations (PDF) |
| 163 | Koch's postulates for cholesterol | 33.6 | 77 | Citations (PDF) |
| 164 | Molecular genetics of the LDL receptor gene in familial hypercholesterolemia | 4.5 | 1,101 | Citations (PDF) |
| 165 | Protein farnesyltransferase and geranylgeranyltransferase share a common α subunit | 33.6 | 396 | Citations (PDF) |
| 166 | cDNA cloning and expression of the peptide-binding β subunit of rat p21rasfarnesyltransferase, the counterpart of yeast DPR1/RAM1 | 33.6 | 199 | Citations (PDF) |
| 167 | The low-density lipoprotein receptor-related protein: double agent or decoy? | 3.9 | 159 | Citations (PDF) |
| 168 | Regulation of the mevalonate pathway | 37.9 | 5,275 | Citations (PDF) |
| 169 | Purification of ras farnesyl:Protein transferase | 3.5 | 34 | Citations (PDF) |
| 170 | Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides | 33.6 | 847 | Citations (PDF) |
| 171 | cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19 | 2.8 | 84 | Citations (PDF) |
| 172 | THE LDL RECEPTOR LOCUS IN FAMILIAL HYPERCHOLESTEROLEMIA: Mutational Analysis of a Membrane Protein | 7.2 | 680 | Citations (PDF) |
| 173 | Low density lipoprotein receptor-related protein mediates endocytosis of monoclonal antibodies in cultured cells and rabbit liver. | 2.2 | 117 | Citations (PDF) |
| 174 | Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein. | 2.2 | 211 | Citations (PDF) |
| 175 | Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein. | 2.2 | 429 | Citations (PDF) |
| 176 | NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. | 2.2 | 858 | Citations (PDF) |
| 177 | Identification of nucleotides responsible for enhancer activity of sterol regulatory element in low density lipoprotein receptor gene. | 2.2 | 216 | Citations (PDF) |
| 178 | Overexpression of human low density lipoprotein receptors leads to accelerated catabolism of Lp(a) lipoprotein in transgenic mice. | 10.6 | 186 | Citations (PDF) |
| 179 | Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. | 7.5 | 567 | Citations (PDF) |
| 180 | Stoichiometric Binding of Low Density Lipoprotein (LDL) and Monoclonal Antibodies to Ldl Receptors in a Solid Phase Assay | 2.2 | 34 | Citations (PDF) |
| 181 | Purification of Oxysterol Binding Protein from Hamster Liver Cytosol | 2.2 | 112 | Citations (PDF) |
| 182 | Purification of a sarcoplasmic reticulum protein that binds Ca2+ and plasma lipoproteins | 2.2 | 58 | Citations (PDF) |
| 183 | Molecular cloning of a histidine-rich Ca2+-binding protein of sarcoplasmic reticulum that contains highly conserved repeated elements | 2.2 | 84 | Citations (PDF) |
| 184 | cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper | 2.2 | 144 | Citations (PDF) |
| 185 | Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells | 2.2 | 148 | Citations (PDF) |
| 186 | Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins | 2.2 | 290 | Citations (PDF) |
| 187 | Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors. | 10.6 | 134 | Citations (PDF) |
| 188 | Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 7.5 | 178 | Citations (PDF) |
| 189 | Localization of mRNA for low density lipoprotein receptor and a cholesterol synthetic enzyme in rabbit nervous system by in situ hybridization. | 7.5 | 74 | Citations (PDF) |
| 190 | Purification of a protein doublet that binds to six TGG-containing sequences in the promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 2.2 | 47 | Citations (PDF) |
| 191 | Mutational analysis of the ligand binding domain of the low density lipoprotein receptor. | 2.2 | 269 | Citations (PDF) |
| 192 | Multivalent control of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mevalonate-derived product inhibits translation of mRNA and accelerates degradation of enzyme. | 2.2 | 307 | Citations (PDF) |
| 193 | Human low density lipoprotein receptor expressed in Xenopus oocytes. Conserved signals for O-linked glycosylation and receptor-mediated endocytosis. | 2.2 | 38 | Citations (PDF) |
| 194 | Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. | 2.2 | 259 | Citations (PDF) |
| 195 | Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element. | 2.2 | 186 | Citations (PDF) |
| 196 | Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutaryl-coenzyme A synthase. | 2.2 | 152 | Citations (PDF) |
| 197 | Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletions. | 10.6 | 69 | Citations (PDF) |
| 198 | Optional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamsters. | 7.5 | 39 | Citations (PDF) |
| 199 | mRNA for low density lipoprotein receptor in brain and spinal cord of immature and mature rabbits. | 7.5 | 62 | Citations (PDF) |
| 200 | Identification of promoter elements required for in vitro transcription of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. | 7.5 | 82 | Citations (PDF) |
| 201 | Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia | 33.6 | 312 | Citations (PDF) |
| 202 | Deletion in the Gene for the Low-Density-Lipoprotein Receptor in a Majority of French Canadians with Familial Hypercholesterolemia | 34.5 | 293 | Citations (PDF) |
| 203 | 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoterCell, 1987, 48, 1061-1069 | 33.6 | 229 | Citations (PDF) |
| 204 | Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region | 37.9 | 420 | Citations (PDF) |
| 205 | First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins. | 2.2 | 117 | Citations (PDF) |
| 206 | Self-association of the low density lipoprotein receptor mediated by the cytoplasmic domain. | 2.2 | 94 | Citations (PDF) |
| 207 | Purification of catalytic subunit of low density lipoprotein receptor kinase and identification of heat-stable activator protein. | 2.2 | 19 | Citations (PDF) |
| 208 | Three direct repeats and a TATA-like sequence are required for regulated expression of the human low density lipoprotein receptor gene. | 2.2 | 171 | Citations (PDF) |
| 209 | Phosphorylation of serine 833 in cytoplasmic domain of low density lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II. | 2.2 | 57 | Citations (PDF) |
| 210 | The Lebanese allele at the low density lipoprotein receptor locus. Nonsense mutation produces truncated receptor that is retained in endoplasmic reticulum. | 2.2 | 253 | Citations (PDF) |
| 211 | The J. D. mutation in familial hypercholesterolemia: Amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors | 33.6 | 384 | Citations (PDF) |
| 212 | Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17 alpha-ethinyl estradiol. | 7.5 | 201 | Citations (PDF) |
| 213 | Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia. | 7.5 | 155 | Citations (PDF) |
| 214 | Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. | 7.5 | 316 | Citations (PDF) |
| 215 | A Receptor-Mediated Pathway for Cholesterol Homeostasis(Nobel Lecture) | 4.7 | 59 | Citations (PDF) |
| 216 | Ein Rezeptor-vermittelter Stoffwechselweg für die Cholesterin-Homöostase (Nobel-Vortrag) | 1.4 | 14 | Citations (PDF) |
| 217 | Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. I. Isolation and sequencing of a full-length cDNA. | 2.2 | 106 | Citations (PDF) |
| 218 | Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. II. Isolation of the gene and characterization of the 5' flanking region. | 2.2 | 51 | Citations (PDF) |
| 219 | Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts. | 2.2 | 166 | Citations (PDF) |
| 220 | Deletion of exon encoding cysteine-rich repeat of low density lipoprotein receptor alters its binding specificity in a subject with familial hypercholesterolemia. | 2.2 | 127 | Citations (PDF) |
| 221 | The LDL Receptor in Familial Hypercholesterolemia: Use of Human Mutations to Dissect a Membrane Protein | 1.6 | 43 | Citations (PDF) |
| 222 | On the origin and prevention of PAIDS (Paralyzed Academic Investigator's Disease Syndrome). | 10.6 | 58 | Citations (PDF) |
| 223 | Familial Hypercholesterolemia: A Genetic Receptor Disease | 1.0 | 12 | Citations (PDF) |
| 224 | Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System | 39.8 | 1,601 | Citations (PDF) |
| 225 | Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme | 33.6 | 375 | Citations (PDF) |
| 226 | The Receptor Model for Transport of Cholesterol in Plasmaa | 4.0 | 29 | Citations (PDF) |
| 227 | Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain | 33.6 | 317 | Citations (PDF) |
| 228 | 5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription | 33.6 | 193 | Citations (PDF) |
| 229 | Multiple mRNAs for 3-hydroxy-3-methylglutaryl coenzyme A reductase determined by multiple transcription initiation sites and intron splicing sites in the 5'-untranslated region. | 2.2 | 120 | Citations (PDF) |
| 230 | Domain structure of 3-hydroxy-3-methylglutaryl coenzyme A reductase, a glycoprotein of the endoplasmic reticulum. | 2.2 | 290 | Citations (PDF) |
| 231 | Sterols Accelerate Degradation of Hamster 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Encoded by a Constitutively Expressed cDNA | 2.5 | 39 | Citations (PDF) |
| 232 | Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia | 34.5 | 463 | Citations (PDF) |
| 233 | Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum | 37.9 | 278 | Citations (PDF) |
| 234 | How LDL Receptors Influence Cholesterol and Atherosclerosis | 0.1 | 365 | Citations (PDF) |
| 235 | HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions | 33.6 | 564 | Citations (PDF) |
| 236 | Increase in membrane cholesterol: A possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells | 33.6 | 117 | Citations (PDF) |
| 237 | Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor | 33.6 | 391 | Citations (PDF) |
| 238 | The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA | 33.6 | 1,480 | Citations (PDF) |
| 239 | Assignment of the human gene for the low density lipoprotein receptor to chromosome 19: synteny of a receptor, a ligand, and a genetic disease. | 7.5 | 119 | Citations (PDF) |
| 240 | Visualization of acidic organelles in intact cells by electron microscopy. | 7.5 | 255 | Citations (PDF) |
| 241 | Imaging of hepatic low density lipoprotein receptors by radionuclide scintiscanning in vivo. | 7.5 | 28 | Citations (PDF) |
| 242 | Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol | 3.6 | 353 | Citations (PDF) |
| 243 | Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe heritable hyperlipidemic rabbits. | 10.6 | 56 | Citations (PDF) |
| 244 | LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis | 17.4 | 2,254 | Citations (PDF) |
| 245 | Recycling receptors: The round-trip itinerary of migrant membrane proteins | 33.6 | 808 | Citations (PDF) |
| 246 | The LDL receptor locus in familial hypercholesterolemia: Multiple mutations disrupt transport and processing of a membrane receptor | 33.6 | 278 | Citations (PDF) |
| 247 | Defective Lipoprotein Receptors and Atherosclerosis | 34.5 | 480 | Citations (PDF) |
| 248 | 3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides. | 7.5 | 143 | Citations (PDF) |
| 249 | cDNA cloning of the bovine low density lipoprotein receptor: feedback regulation of a receptor mRNA. | 7.5 | 159 | Citations (PDF) |
| 250 | Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes. | 7.5 | 505 | Citations (PDF) |
| 251 | Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor. | 2.2 | 346 | Citations (PDF) |
| 252 | Mutant clone of Chinese hamster ovary cells lacking 3-hydroxy-3 -methylglutaryl coenzyme A reductase. | 2.2 | 60 | Citations (PDF) |
| 253 | Visualization of lipoprotein receptors by ligand blotting. | 2.2 | 256 | Citations (PDF) |
| 254 | Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe. | 2.2 | 192 | Citations (PDF) |
| 255 | Amplification of the gene for 3-hydroxy-3-methylglutaryl coenzyme A reductase, but not for the 53-kDa protein, in UT-1 cells. | 2.2 | 185 | Citations (PDF) |
| 256 | Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptors | 3.6 | 88 | Citations (PDF) |
| 257 | Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic. | 10.6 | 503 | Citations (PDF) |
| 258 | Ultrastructural analysis of crystalloid endoplasmic reticulum in ut-1 cells and its disappearance in response to cholesterol | 2.4 | 93 | Citations (PDF) |
| 259 | Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits. | 7.5 | 197 | Citations (PDF) |
| 260 | The LDL Receptor Defect in Familial Hypercholesterolemia: Implications for Pathogenesis and Therapy | 3.1 | 186 | Citations (PDF) |
| 261 | Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA. | 7.5 | 144 | Citations (PDF) |
| 262 | Recycling of Cell-surface Receptors: Observations from the LDL Receptor System | 1.6 | 70 | Citations (PDF) |
| 263 | Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells. | 7.5 | 205 | Citations (PDF) |
| 264 | Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | 7.5 | 247 | Citations (PDF) |
| 265 | Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor. | 7.5 | 252 | Citations (PDF) |
| 266 | Identification of a cholesterol-regulated 53,000-dalton cytosolic protein in UT-1 cells and cloning of its cDNA. | 7.5 | 30 | Citations (PDF) |
| 267 | Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia | 33.6 | 250 | Citations (PDF) |
| 268 | Immunoblot analysis of low density lipoprotein receptors in fibroblasts from subjects with familial hypercholesterolemia. | 2.2 | 163 | Citations (PDF) |
| 269 | Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes. | 2.2 | 278 | Citations (PDF) |
| 270 | Purification of the low density lipoprotein receptor, an acidic glycoprotein of 164,000 molecular weight. | 2.2 | 348 | Citations (PDF) |
| 271 | Isolation of Chinese hamster cell mutants defective in the receptor-mediated endocytosis of low density lipoprotein | 4.1 | 127 | Citations (PDF) |
| 272 | Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. | 7.5 | 297 | Citations (PDF) |
| 273 | Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia. | 7.5 | 236 | Citations (PDF) |
| 274 | Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog. | 7.5 | 394 | Citations (PDF) |
| 275 | Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits. | 7.5 | 289 | Citations (PDF) |
| 276 | Feedback Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase in Livers of Mice Treated with Mevinolin, a Competitive Inhibitor of the Reductase | 10.6 | 294 | Citations (PDF) |
| 277 | .beta.-Carotene as a probe of lipid domains of reconstituted human plasma low-density lipoprotein: induced circular dichroism | 2.4 | 16 | Citations (PDF) |
| 278 | The LDL Receptor Locus and the Genetics of Familial Hypercholesterolemia | 7.2 | 224 | Citations (PDF) |
| 279 | Low Density Lipoprotein Receptors in Bovine Adrenal Cortex. I. Receptor-Mediated Uptake of Low Density Lipoprotein and Utilization of Its Cholesterol for Steroid Synthesis in Cultured Adrenocortical Cells* | 2.5 | 170 | Citations (PDF) |
| 280 | Low Density Lipoprotein Receptors in Bovine Adrenal Cortex. II. Low Density Lipoprotein Binding to Membranes Prepared from Fresh Tissue* | 2.5 | 174 | Citations (PDF) |
| 281 | Synthesis of ubiquinone and cholesterol in human fibroblasts: Regulation of a branched pathway | 2.8 | 155 | Citations (PDF) |
| 282 | Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition | 7.5 | 2,284 | Citations (PDF) |
| 283 | Demonstration of low density lipoprotein receptors in mouse teratocarcinoma stem cells and description of a method for producing receptor-deficient mutant mice | 7.5 | 27 | Citations (PDF) |
| 284 | Squalene synthetase activity in human fibroblasts: Regulation via the low density lipoprotein receptor | 7.5 | 93 | Citations (PDF) |
| 285 | Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states. | 2.2 | 304 | Citations (PDF) |
| 286 | Separate mechanisms for the uptake of high and low density lipoproteins by mouse adrenal gland in vivo. | 2.2 | 144 | Citations (PDF) |
| 287 | Occurrence of low density lipoprotein receptors within large pits on the surface of human fibroblasts as demonstrated by freeze-etching | 3.1 | 109 | Citations (PDF) |
| 288 | Howard Hughes Medical Institute | 34.5 | 0 | Citations (PDF) |
| 289 | Inhibition of cholesteryl ester formation in human fibroblasts by an analogue of 7-ketocholesterol and by progesterone | 7.5 | 81 | Citations (PDF) |
| 290 | Receptor-mediated uptake of low density lipoprotein reconstituted with 25-hydroxycholesteryl oleate suppresses 3-hydroxy-3-methylglutaryl-coenzyme A reductase and inhibits growth of human fibroblasts | 7.5 | 47 | Citations (PDF) |
| 291 | Regulation of cholesterol synthesis in rat adrenal gland through coordinate control of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase activities. | 7.5 | 97 | Citations (PDF) |
| 292 | Specific, saturable, and high affinity binding of 125I-low density lipoprotein to glass beads | 2.1 | 42 | Citations (PDF) |
| 293 | Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts | 33.6 | 667 | Citations (PDF) |
| 294 | Genetics of the LDL receptor: Evidence that the mutations affecting binding and internalization are allelic | 33.6 | 167 | Citations (PDF) |
| 295 | Atherosclerosis: The low-density lipoprotein receptor hypothesis | 9.1 | 353 | Citations (PDF) |
| 296 | Lipoprotein-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesteryl ester metabolism in the adrenal gland of the rat. | 2.2 | 197 | Citations (PDF) |
| 297 | The low density lipoprotein pathway in human fibroblasts | 6.7 | 3 | Citations (PDF) |
| 298 | The low density lipoprotein pathway in human fibroblasts | 6.7 | 13 | Citations (PDF) |
| 299 | Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein | 33.6 | 228 | Citations (PDF) |
| 300 | Heterozygous familial hypercholesterolemia: Failure of normal allele to compensate for mutant allele at a regulated genetic locus | 33.6 | 77 | Citations (PDF) |
| 301 | Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans | 33.6 | 635 | Citations (PDF) |
| 302 | Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat. | 7.5 | 75 | Citations (PDF) |
| 303 | Familial Hypercholesterolemia: A Genetic Defect in the Low-Density Lipoprotein Receptor | 34.5 | 194 | Citations (PDF) |
| 304 | Familial pseudomembranous colitis and its relation to lincomycin therapy | 0.8 | 10 | Citations (PDF) |
| 305 | Genetic and hormonal control of male sexual differentiation | 4.1 | 34 | Citations (PDF) |
| 306 | Prolonged hypouricemia associated with acute chlorprothixene ingestion | 6.1 | 9 | Citations (PDF) |
| 307 | Regulation of the activity of the low density lipoprotein receptor in human fibroblasts | 33.6 | 478 | Citations (PDF) |
| 308 | Familial hypercholesterolemia | 2.0 | 113 | Citations (PDF) |
| 309 | Linkage investigation of a large family with Reifenstein's syndrome | 2.1 | 4 | Citations (PDF) |
| 310 | Familial Incomplete Male Pseudohermaphroditism, Type 1 | 34.5 | 202 | Citations (PDF) |
| 311 | Familial Incomplete Male Pseudohermaphroditism, Type 2 | 34.5 | 634 | Citations (PDF) |
| 312 | Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity | 7.5 | 565 | Citations (PDF) |
| 313 | Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial Hypercholesterolemia | 7.5 | 283 | Citations (PDF) |
| 314 | Suppression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity and Inhibition of Growth of Human Fibroblasts by 7-Ketocholesterol | 2.2 | 478 | Citations (PDF) |
| 315 | Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts | 2.2 | 1,393 | Citations (PDF) |
| 316 | Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human Fibroblasts | 2.2 | 526 | Citations (PDF) |
| 317 | Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts by Lipoproteins | 7.5 | 333 | Citations (PDF) |
| 318 | Familial Hypercholesterolemia: Identification of a Defect in the Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity Associated with Overproduction of Cholesterol | 7.5 | 427 | Citations (PDF) |
| 319 | Genetic Aspects of Hyperlipidemia in Coronary Heart Disease | 1.0 | 11 | Citations (PDF) |
| 320 | Studies on the pathogenesis of the pseudohermaphroditism in the mouse with testicular feminization | 10.6 | 150 | Citations (PDF) |
| 321 | Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis | 0.7 | 361 | Citations (PDF) |
| 322 | BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver | 0.7 | 31 | Citations (PDF) |
| 323 | Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection | 0.7 | 329 | Citations (PDF) |
| 324 | Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | 0.7 | 43 | Citations (PDF) |
