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161 papers • 95,227 citations • Sorted by year • Download PDF (PDF by citations)
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1Enhanced autophagy in <i>Becn1<sup>F121A/F121A</sup></i> knockin mice counteracts aging-related neural stem cell exhaustion and dysfunction
Autophagy, 2022, 18, 409-422
13.823Citations (PDF)
2Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification14.110Citations (PDF)
3STING controls energy stress-induced autophagy and energy metabolism via STX174.837Citations (PDF)
4FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner4.14Citations (PDF)
5Novel Bcl-2 Inhibitors Selectively Disrupt the Autophagy-Specific Bcl-2–Beclin 1 Protein–Protein Interaction
ACS Medicinal Chemistry Letters, 2022, 13, 1510-1516
3.69Citations (PDF)
6GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex
Autophagy, 2021, 17, 2891-2904
13.826Citations (PDF)
7Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin7.756Citations (PDF)
8An autophagy-related protein Becn2 regulates cocaine reward behaviors in the dopaminergic system
Science Advances, 2021, 7,
11.310Citations (PDF)
9Autophagy stimulation reduces ocular hypertension in a murine glaucoma model via autophagic degradation of mutant myocilin
JCI Insight, 2021, 6,
5.535Citations (PDF)
10The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance
FASEB Journal, 2020, 34, 3129-3150
0.717Citations (PDF)
11Autophagy in Human Diseases
New England Journal of Medicine, 2020, 383, 1564-1576
25.5698Citations (PDF)
12Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia
JCI Insight, 2020, 5,
5.541Citations (PDF)
13Sorting nexin 5 mediates virus-induced autophagy and immunity
Nature, 2020, 589, 456-461
40.161Citations (PDF)
14TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise
Nature, 2020, 578, 605-609
40.150Citations (PDF)
15Beclin 2 negatively regulates innate immune signaling and tumor development
Journal of Clinical Investigation, 2020, 130, 5349-5369
9.118Citations (PDF)
16Protective Effect of SMAD‐Specific E3 Ubiquitin Protein Ligase 1 in Alcoholic Steatohepatitis in Mice
Hepatology Communications, 2019, 3, 1450-1458
4.97Citations (PDF)
17Biological Functions of Autophagy Genes: A Disease Perspective
Cell, 2019, 176, 11-42
35.11,918Citations (PDF)
18Increased autophagy blocks HER2-mediated breast tumorigenesis7.795Citations (PDF)
19Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
Cell Host and Microbe, 2018, 23, 177-190.e4
15.291Citations (PDF)
20Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 201813.74,465Citations (PDF)
21Autophagy balances inflammation in innate immunity
Autophagy, 2018, 14, 243-251
13.8412Citations (PDF)
22Autophagy and the cell biology of age-related disease
Nature Cell Biology, 2018, 20, 1338-1348
10.5317Citations (PDF)
23Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice
Nature, 2018, 558, 136-140
40.1473Citations (PDF)
24Beclin-1-Dependent Autophagy Protects the Heart During Sepsis
Circulation, 2018, 138, 2247-2262
19.4277Citations (PDF)
25Cell Penetration Profiling Using the Chloroalkane Penetration Assay15.7120Citations (PDF)
26Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing39.3378Citations (PDF)
27High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding
ACS Chemical Biology, 2018, 13, 2247-2260
3.953Citations (PDF)
28An increase in LRRK2 suppresses autophagy and enhances Dectin-1–induced immunity in a mouse model of colitis13.1105Citations (PDF)
29BECN2 interacts with ATG14 through a metastable coiled‐coil to mediate autophagy
Protein Science, 2017, 26, 972-984
5.910Citations (PDF)
30Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy15.7125Citations (PDF)
31Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles39.3660Citations (PDF)
32Molecular definitions of autophagy and related processes
EMBO Journal, 2017, 36, 1811-1836
7.41,249Citations (PDF)
33Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor
Cell, 2017, 168, 224-238.e10
35.1606Citations (PDF)
34The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense
Cell Host and Microbe, 2017, 21, 59-72
15.2168Citations (PDF)
35Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research7.7130Citations (PDF)
36Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein3.413Citations (PDF)
37Emerging functions of the Fanconi anemia pathway at a glance
Journal of Cell Science, 2017, 130, 2657-2662
3.234Citations (PDF)
38The Autophagy-Related Beclin-1 Protein Requires the Coiled-Coil and BARA Domains To Form a Homodimer with Submicromolar Affinity
Biochemistry, 2017, 56, 6639-6651
2.915Citations (PDF)
39A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease
PLoS Genetics, 2017, 13, e1006962
3.3123Citations (PDF)
40mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy
Journal of Clinical Investigation, 2017, 127, 3717-3729
9.173Citations (PDF)
41Downregulation of autophagy is associated with severe ischemia-reperfusion-induced acute kidney injury in overexpressing C-reactive protein mice
PLoS ONE, 2017, 12, e0181848
2.533Citations (PDF)
42BECN Homologs And ATG14 Form A Metastable Coiled‐Coil To Mediate Autophagy
FASEB Journal, 2017, 31,
0.70Citations (PDF)
43Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
Cancer Cell, 2016, 30, 147-160
33.4420Citations (PDF)
44Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis7.717Citations (PDF)
45Fanconi Anemia Proteins Function in Mitophagy and Immunity
Cell, 2016, 165, 867-881
35.1202Citations (PDF)
46Does Autophagy Mediate Cardiac Myocyte Death During Stress?
Circulation Research, 2016, 119, 893-895
12.831Citations (PDF)
47Response by Shirakabe et al to Letter Regarding Article, “Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure”
Circulation, 2016, 134,
19.45Citations (PDF)
48Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 2016, 12, 1-222
13.84,327Citations (PDF)
49Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation
Cell Host and Microbe, 2016, 19, 91-101
15.252Citations (PDF)
50Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart Failure
Circulation, 2016, 133, 1249-1263
19.4351Citations (PDF)
51αKlotho Mitigates Progression of AKI to CKD through Activation of Autophagy0.4150Citations (PDF)
52Novel functions of Fanconi anemia proteins in selective autophagy and inflammation
Oncotarget, 2016, 7, 50820-50821
1.76Citations (PDF)
53Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis
Oncotarget, 2016, 7, 67919-67933
1.717Citations (PDF)
54Development of autophagy inducers in clinical medicine9.1281Citations (PDF)
55Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiology
Trends in Cell Biology, 2015, 25, 533-544
15.3144Citations (PDF)
56Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis
Cell Host and Microbe, 2015, 17, 820-828
15.2297Citations (PDF)
57Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis
EBioMedicine, 2015, 2, 255-263
10.095Citations (PDF)
58Autophagy in malignant transformation and cancer progression
EMBO Journal, 2015, 34, 856-880
7.4992Citations (PDF)
59BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy
Autophagy, 2015, 11, 452-459
13.879Citations (PDF)
60GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion7.7158Citations (PDF)
61iScreen: Image-Based High-Content RNAi Screening Analysis Tools
SLAS Discovery, 2015, 20, 998-1002
2.43Citations (PDF)
62GABARAP-mediated targeting of PI4K2A/PI4KIIα to autophagosomes regulates PtdIns4P-dependent autophagosome-lysosome fusion
Autophagy, 2015, 11, 2127-2129
13.831Citations (PDF)
63A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells
MBio, 2015, 6,
4.5116Citations (PDF)
64Identification of secreted proteins that reflect autophagy dynamics within tumor cells
Autophagy, 2015, 11, 60-74
13.894Citations (PDF)
65Author response: The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
2015, ,
2Citations (PDF)
66Role of Autophagy in DNA Virus Infections<i>in VIVO</i>
2014, , 33-48
0Citations (PDF)
67Targeting γ-Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy
Journal of Biological Chemistry, 2014, 289, 8029-8040
2.340Citations (PDF)
68Autophagy is essential for cardiac morphogenesis during vertebrate development
Autophagy, 2014, 10, 572-587
13.8115Citations (PDF)
69Computational detection and suppression of sequence-specific off-target phenotypes from whole genome RNAi screens
Nucleic Acids Research, 2014, 42, 8214-8222
16.221Citations (PDF)
70Metabolic Control of Autophagy
Cell, 2014, 159, 1263-1276
35.1694Citations (PDF)
71Autophagy is required for G<sub>1</sub>/G<sub>0</sub>quiescence in response to nitrogen starvation in<i>Saccharomyces cerevisiae</i>
Autophagy, 2014, 10, 1702-1711
13.850Citations (PDF)
72To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate
Cell, 2014, 157, 65-75
35.1573Citations (PDF)
73Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis
Autophagy, 2014, 10, 1256-1271
13.890Citations (PDF)
74TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition
Developmental Cell, 2014, 30, 394-409
7.8261Citations (PDF)
75Autophagy and Cancer Metabolism
Methods in Enzymology, 2014, , 25-57
1.0107Citations (PDF)
76Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism
Cell, 2013, 154, 1085-1099
35.1126Citations (PDF)
77EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
Cell, 2013, 154, 1269-1284
35.1432Citations (PDF)
78Identification of a candidate therapeutic autophagy-inducing peptide
Nature, 2013, 494, 201-206
40.1647Citations (PDF)
79Autophagy in Human Health and Disease25.52,117Citations (PDF)
80Intestinal Epithelial Autophagy Is Essential for Host Defense against Invasive Bacteria
Cell Host and Microbe, 2013, 13, 723-734
15.2250Citations (PDF)
81Autophagy in Human Health and Disease
New England Journal of Medicine, 2013, 368, 1845-1846
25.5581Citations (PDF)
82Autosis is a Na <sup>+</sup> ,K <sup>+</sup> -ATPase–regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia–ischemia7.7489Citations (PDF)
83Autophagy genes function in apoptotic cell corpse clearance during<i><i>C. elegans</i></i>embryonic development
Autophagy, 2013, 9, 138-149
13.845Citations (PDF)
84Exercise induces autophagy in peripheral tissues and in the brain
Autophagy, 2012, 8, 1548-1551
13.8201Citations (PDF)
85Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
Nature, 2012, 481, 511-515
40.1949Citations (PDF)
86Autophagy modulation as a potential therapeutic target for diverse diseases39.31,239Citations (PDF)
87Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 2012, 8, 445-544
13.82,928Citations (PDF)
88Image-based genome-wide siRNA screen identifies selective autophagy factors
Nature, 2011, 480, 113-117
40.1406Citations (PDF)
89Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
EMBO Journal, 2011, 30, 1195-1208
7.4194Citations (PDF)
90Autophagy in immunity and inflammation
Nature, 2011, 469, 323-335
40.12,689Citations (PDF)
91Selective autophagy and viruses
Autophagy, 2011, 7, 260-265
13.856Citations (PDF)
92A comprehensive glossary of autophagy-related molecules and processes (2<sup>nd</sup>edition)
Autophagy, 2011, 7, 1273-1294
13.8243Citations (PDF)
93Calcipotriol Induces Autophagy in HeLa Cells and Keratinocytes0.736Citations (PDF)
94Autophagy and Longevity: Lessons from C. elegans0.021Citations (PDF)
95The Beclin 1 interactome4.2557Citations (PDF)
96Autophagy in cellular growth control
FEBS Letters, 2010, 584, 1417-1426
2.8135Citations (PDF)
97Snapshot of the network
Nature, 2010, 466, 38-39
40.122Citations (PDF)
98Autophagy in mammalian development and differentiation
Nature Cell Biology, 2010, 12, 823-830
10.51,240Citations (PDF)
99The CD40-Autophagy Pathway Is Needed for Host Protection Despite IFN-Γ-Dependent Immunity and CD40 Induces Autophagy via Control of P21 Levels
PLoS ONE, 2010, 5, e14472
2.566Citations (PDF)
100A comprehensive glossary of autophagy-related molecules and processes
Autophagy, 2010, 6, 438-448
13.8139Citations (PDF)
101Autophagy and the Integrated Stress Response
Molecular Cell, 2010, 40, 280-293
14.22,816Citations (PDF)
102Methods in Mammalian Autophagy Research
Cell, 2010, 140, 313-326
35.13,784Citations (PDF)
103Autophagy Protects against Sindbis Virus Infection of the Central Nervous System
Cell Host and Microbe, 2010, 7, 115-127
15.2451Citations (PDF)
104Autophagy and innate immunity: Triggering, targeting and tuning5.4105Citations (PDF)
105Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy
Journal of Biological Chemistry, 2009, 284, 2719-2728
2.3230Citations (PDF)
106Autophagy genes protect against <i>Salmonella typhimurium</i> infection and mediate insulin signaling-regulated pathogen resistance7.7190Citations (PDF)
107Ceramide-induced autophagy: To junk or to protect cells?
Autophagy, 2009, 5, 558-560
13.879Citations (PDF)
108Autophagy, antiviral immunity, and viral countermeasures3.6103Citations (PDF)
109Viruses and autophagy
Reviews in Medical Virology, 2009, 19, 359-378
7.1228Citations (PDF)
110Autophagy genes in immunity
Nature Immunology, 2009, 10, 461-470
13.1379Citations (PDF)
111Autophagy, Immunity, and Microbial Adaptations
Cell Host and Microbe, 2009, 5, 527-549
15.2718Citations (PDF)
112Autophagy in Mammalian Antiviral Immunity0.029Citations (PDF)
113Autophagy in C. elegans
WormBook, 2009, , 1-26
5.275Citations (PDF)
114Autophagy fights disease through cellular self-digestion
Nature, 2008, 451, 1069-1075
40.15,481Citations (PDF)
115p53: The Janus of autophagy?
Nature Cell Biology, 2008, 10, 637-639
10.5190Citations (PDF)
116Autophagic cell death: the story of a misnomer31.41,245Citations (PDF)
117Autophagy and viral neurovirulence
Cellular Microbiology, 2008, 10, 1747-1756
1.475Citations (PDF)
118JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy
Molecular Cell, 2008, 30, 678-688
14.21,132Citations (PDF)
119Autophagy in the Pathogenesis of Disease
Cell, 2008, 132, 27-42
35.15,904Citations (PDF)
120SnapShot: Macroautophagy
Cell, 2008, 132, 162.e1-162.e3
35.134Citations (PDF)
121The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
Developmental Cell, 2008, 15, 344-357
7.8452Citations (PDF)
122Autophagy is an adaptive response in desmin-related cardiomyopathy7.7201Citations (PDF)
123The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice9.1883Citations (PDF)
124Molecular basis of the regulation of Beclin 1-dependent autophagy by the γ-herpesvirus 68 Bcl-2 homolog M11
Autophagy, 2008, 4, 989-997
13.8145Citations (PDF)
125Viral evasion of autophagy
Autophagy, 2008, 4, 280-285
13.872Citations (PDF)
126Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 2008, 4, 151-175
13.81,948Citations (PDF)
127Bcl-2 family members: Dual regulators of apoptosis and autophagy
Autophagy, 2008, 4, 600-606
13.8709Citations (PDF)
128Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
Circulation Research, 2007, 100, 914-922
12.81,306Citations (PDF)
129How Shall I Eat Thee?
Autophagy, 2007, 3, 413-416
13.8129Citations (PDF)
130Autophagy Genes Protect Against Disease Caused by Polyglutamine Expansion Proteins in<i>Caenorhabditis elegans</i>
Autophagy, 2007, 3, 21-25
13.8118Citations (PDF)
131Autophagy is Required for Dietary Restriction-Mediated Life Span Extension in<i>C. elegans</i>
Autophagy, 2007, 3, 597-599
13.8282Citations (PDF)
132Analysis of the Role of Autophagy in Replication of Herpes Simplex Virus in Cell Culture
Journal of Virology, 2007, 81, 12128-12134
3.6131Citations (PDF)
133Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
Cell, 2007, 128, 931-946
35.1552Citations (PDF)
134HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein
Cell Host and Microbe, 2007, 1, 23-35
15.2703Citations (PDF)
135Cardiac autophagy is a maladaptive response to hemodynamic stress
Journal of Clinical Investigation, 2007, 117, 1782-1793
9.1638Citations (PDF)
136Autophagy and cancer
Nature, 2007, 446, 745-747
40.1646Citations (PDF)
137Unveiling the roles of autophagy in innate and adaptive immunity
Nature Reviews Immunology, 2007, 7, 767-777
17.9743Citations (PDF)
138Autophagy in Antiviral Host Defense
2006, , 227-241
2Citations (PDF)
139PKR-Dependent Xenophagic Degradation of Herpes Simplex Virus Type 1
Autophagy, 2006, 2, 24-29
13.8312Citations (PDF)
140Unraveling the Role of Autophagy in Cancer
Autophagy, 2006, 2, 65-66
13.870Citations (PDF)
141HIV and CXCR4 in a kiss of autophagic death
Journal of Clinical Investigation, 2006, 116, 2078-2080
9.117Citations (PDF)
142Autophagy in cell death: an innocent convict?
Journal of Clinical Investigation, 2005, 115, 2679-2688
9.11,426Citations (PDF)
143The Evolutionarily Conserved Domain of Beclin 1 is Required for Vps34 Binding, Autophagy, and Tumor Suppressor Function
Autophagy, 2005, 1, 46-52
13.8363Citations (PDF)
144Eating Oneself and Uninvited Guests
Cell, 2005, 120, 159-162
35.1651Citations (PDF)
145Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
Cell, 2005, 121, 567-577
35.1702Citations (PDF)
146Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
Cell, 2005, 122, 927-939
35.13,029Citations (PDF)
147Digesting Oneself and Digesting Microbes
2005, , 245-279
4Citations (PDF)
148Development by Self-Digestion
Developmental Cell, 2004, 6, 463-477
7.83,259Citations (PDF)
149Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans
Science, 2003, 301, 1387-1391
38.21,060Citations (PDF)
150Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
Journal of Clinical Investigation, 2003, 112, 1809-1820
9.11,897Citations (PDF)
151Regulation of starvation- and virus-induced autophagy by the eIF2  kinase signaling pathway7.7656Citations (PDF)
152Identification of Genes Involved in the Host Response to Neurovirulent Alphavirus Infection
Journal of Virology, 2001, 75, 10431-10445
3.688Citations (PDF)
153Sindbis Virus Vector System for Functional Analysis of Apoptosis Regulators
Methods in Enzymology, 2000, , 492-508
1.043Citations (PDF)
154FRET: A Spectral Ruler for Interacting Molecules Involved in Apoptosis0.51Citations (PDF)
155Induction of autophagy and inhibition of tumorigenesis by beclin 1
Nature, 1999, 402, 672-676
40.12,851Citations (PDF)
156Cloning and Genomic Organization of Beclin 1, a Candidate Tumor Suppressor Gene on Chromosome 17q21
Genomics, 1999, 59, 59-65
2.7658Citations (PDF)
157Sindbis Virus Induces Apoptosis through a Caspase-Dependent, CrmA-Sensitive Pathway
Journal of Virology, 1998, 72, 452-459
3.6109Citations (PDF)
158Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein
Journal of Virology, 1998, 72, 8586-8596
3.6949Citations (PDF)
159The role of antibody in recovery from alphavirus encephalitis
Immunological Reviews, 1997, 159, 155-161
6.8107Citations (PDF)
160Bax-independent inhibition of apoptosis by Bcl-XL
Nature, 1996, 379, 554-556
40.1434Citations (PDF)
161The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
ELife, 0, 4,
1.6154Citations (PDF)