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157 PR articles • 39,297 PR citations • Sorted by year • Download PDF (PDF by citations)
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1TOP2B is required for compartment strength changes upon retinoic acid treatment in SH-SY5Y cells2.20Citations (PDF)
2Rules of engagement for condensins and cohesins guide mitotic chromosome formation
Science, 2025, 388,
36.237Citations (PDF)
3Mitotic chromosomes harbor cell type– and species-specific structural features within a universal loop array conformation
Genome Research, 2025, 35, 1733-1744
4.63Citations (PDF)
4Enhancer-driven 3D chromatin domain folding modulates transcription in human mammary tumor cells
Life Science Alliance, 2024, 7, e202302154
2.65Citations (PDF)
5Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
Nature Genetics, 2024, 56, 900-912
25.246Citations (PDF)
6Mitotic chromosomes are self-entangled and disentangle through a topoisomerase-II-dependent two-stage exit from mitosis
Molecular Cell, 2024, 84, 1422-1441.e14
13.338Citations (PDF)
7Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations4.43Citations (PDF)
8The chromosome folding problem and how cells solve it
Cell, 2024, 187, 6424-6450
33.776Citations (PDF)
9The little skate genome and the evolutionary emergence of wing-like fins
Nature, 2023, 616, 495-503
37.963Citations (PDF)
10Mechanisms of insertions at a DNA double-strand break
Molecular Cell, 2023, 83, 2434-2448.e7
13.320Citations (PDF)
11Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
Cell Reports, 2023, 42, 113132
6.318Citations (PDF)
12RNA-mediated symmetry breaking enables singular olfactory receptor choice
Nature, 2023, 625, 181-188
37.940Citations (PDF)
13Revisiting chromatin packaging in mouse sperm
Genome Research, 2023, 33, 2079-2093
4.630Citations (PDF)
14Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions7.2108Citations (PDF)
15Spatial organization of transcribed eukaryotic genes
Nature Cell Biology, 2022, 24, 327-339
16.3111Citations (PDF)
16Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling
Scientific Reports, 2022, 12,
3.423Citations (PDF)
17Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae : An Improved Platform for Comparative Genomics2.436Citations (PDF)
18Nutritional control regulates symbiont proliferation and life history in coral-dinoflagellate symbiosis
BMC Biology, 2022, 20,
3.932Citations (PDF)
19Cohesin-mediated loop anchors confine the locations of human replication origins
Nature, 2022, 606, 812-819
37.9114Citations (PDF)
20CTCF–CTCF loops and intra-TAD interactions show differential dependence on cohesin ring integrity
Nature Cell Biology, 2022, 24, 1516-1527
16.359Citations (PDF)
21Regulation of the mitotic chromosome folding machines
Biochemical Journal, 2022, 479, 2153-2173
3.88Citations (PDF)
22Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization8.864Citations (PDF)
23A cohesin traffic pattern genetically linked to gene regulation8.874Citations (PDF)
24Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers8.8116Citations (PDF)
25Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics
Nature Genetics, 2021, 53, 367-378
25.2126Citations (PDF)
26Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML
JCI Insight, 2021, 6,
5.479Citations (PDF)
27Genetic and spatial organization of the unusual chromosomes of the dinoflagellate Symbiodinium microadriaticum
Nature Genetics, 2021, 53, 618-629
25.280Citations (PDF)
28Chromosome-Level Assembly of the Atlantic Silverside Genome Reveals Extreme Levels of Sequence Diversity and Structural Genetic Variation2.436Citations (PDF)
29Symbiodinium microadriaticum (coral microalgal endosymbiont)
Trends in Genetics, 2021, 37, 1044-1045
9.86Citations (PDF)
30Systematic evaluation of chromosome conformation capture assays
Nature Methods, 2021, 18, 1046-1055
24.6227Citations (PDF)
31Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture13.741Citations (PDF)
32Transcriptional Silencers in Drosophila Serve a Dual Role as Transcriptional Enhancers in Alternate Cellular Contexts
Molecular Cell, 2020, 77, 324-337.e8
13.3120Citations (PDF)
33Detecting chromatin interactions between and along sister chromatids with SisterC
Nature Methods, 2020, 17, 1002-1009
24.648Citations (PDF)
34Expanded encyclopaedias of DNA elements in the human and mouse genomes
Nature, 2020, 583, 699-710
37.92,189Citations (PDF)
35Multi-contact 3C reveals that the human genome during interphase is largely not entangled8.886Citations (PDF)
36rad21 Is Involved in Corneal Stroma Development by Regulating Neural Crest Migration4.45Citations (PDF)
37Ultrastructural Details of Mammalian Chromosome Architecture
Molecular Cell, 2020, 78, 554-565.e7
13.3571Citations (PDF)
38Mechanisms and Functions of Chromosome Compartmentalization6.7269Citations (PDF)
39SPEN integrates transcriptional and epigenetic control of X-inactivation
Nature, 2020, 578, 455-460
37.9193Citations (PDF)
40Clustering of strong replicators associated with active promoters is sufficient to establish an early‐replicating domain
EMBO Journal, 2020, 39,
7.313Citations (PDF)
41The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos13.756Citations (PDF)
42A chromosome folding intermediate at the condensin-to-cohesin transition during telophase
Nature Cell Biology, 2019, 21, 1393-1402
16.3203Citations (PDF)
43Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation
Cell Stem Cell, 2019, 25, 682-696.e8
16.4151Citations (PDF)
44Highly structured homolog pairing reflects functional organization of the Drosophila genome13.769Citations (PDF)
45Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment
Stem Cell Reports, 2019, 13, 193-206
4.433Citations (PDF)
46Heterochromatin drives compartmentalization of inverted and conventional nuclei
Nature, 2019, 570, 395-399
37.9640Citations (PDF)
47Measuring the reproducibility and quality of Hi-C data
Genome Biology, 2019, 20,
8.1169Citations (PDF)
48Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization
Cell, 2019, 176, 1502-1515.e10
33.7453Citations (PDF)
49The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome13.7110Citations (PDF)
50CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning
Genome Research, 2019, 29, 236-249
4.6137Citations (PDF)
51A pathway for mitotic chromosome formation
Science, 2018, 359,
36.2757Citations (PDF)
52Higher-Order Organization Principles of Pre-translational mRNPs
Molecular Cell, 2018, 72, 715-726.e3
13.378Citations (PDF)
53Integrative detection and analysis of structural variation in cancer genomes
Nature Genetics, 2018, 50, 1388-1398
25.2347Citations (PDF)
543C-Based Chromatin Interaction Analyses
Cold Spring Harbor Protocols, 2018, 2018, pdb.top097832
0.313Citations (PDF)
55CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia
Cell, 2018, 174, 172-186.e21
33.783Citations (PDF)
56C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2
Nature Methods, 2018, 15, 433-436
24.6144Citations (PDF)
57Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation
Molecular Cell, 2017, 65, 432-446.e5
13.3331Citations (PDF)
58Epigenetic characteristics of the mitotic chromosome in 1D and 3D6.731Citations (PDF)
59Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation
Methods, 2017, 123, 56-65
3.5301Citations (PDF)
60Shelterin components mediate genome reorganization in response to replication stress7.517Citations (PDF)
61Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization
Cell, 2017, 169, 930-944.e22
33.71,732Citations (PDF)
62SMC complexes differentially compact mitotic chromosomes according to genomic context
Nature Cell Biology, 2017, 19, 1071-1080
16.3154Citations (PDF)
63The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes
Genes and Development, 2017, 31, 2264-2281
4.6179Citations (PDF)
64Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma8.923Citations (PDF)
65Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites7.526Citations (PDF)
66CTCF-mediated topological boundaries during development foster appropriate gene regulation
Genes and Development, 2016, 30, 2657-2662
4.6181Citations (PDF)
67A Guide to Packing Your DNA
Cell, 2016, 165, 259-261
33.72Citations (PDF)
68Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire
Cell Reports, 2016, 14, 896-906
6.386Citations (PDF)
69Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming
Cell Stem Cell, 2016, 18, 611-624
16.4131Citations (PDF)
70TAD disruption as oncogenic driver3.2252Citations (PDF)
71Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma
New England Journal of Medicine, 2016, 374, 1842-1852
34.6554Citations (PDF)
72RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells2.473Citations (PDF)
73Structural organization of the inactive X chromosome in the mouse
Nature, 2016, 535, 575-579
37.9423Citations (PDF)
74SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells
Genome Research, 2016, 26, 1188-1201
4.6106Citations (PDF)
75Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus6.5147Citations (PDF)
76The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer
Cell Reports, 2015, 13, 1855-1867
6.342Citations (PDF)
77Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells
Genome Biology, 2015, 16,
8.1239Citations (PDF)
78Condensin-driven remodelling of X chromosome topology during dosage compensation
Nature, 2015, 523, 240-244
37.9972Citations (PDF)
79Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin
Genome Research, 2015, 25, 504-513
4.6161Citations (PDF)
80Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis
Genes and Development, 2015, 29, 1661-1675
4.6260Citations (PDF)
81Hi-C in Budding Yeast
Cold Spring Harbor Protocols, 2015, 2015, pdb.prot085209
0.322Citations (PDF)
82Measuring Chromatin Structure in Budding Yeast: Figure 1.
Cold Spring Harbor Protocols, 2015, 2015, pdb.top077552
0.34Citations (PDF)
83Chromosome Conformation Capture Carbon Copy (5C) in Budding Yeast
Cold Spring Harbor Protocols, 2015, 2015, pdb.prot085191
0.35Citations (PDF)
84Randomized Ligation Control for Chromosome Conformation Capture
Cold Spring Harbor Protocols, 2015, 2015, pdb.prot085183
0.34Citations (PDF)
85Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C
Cell, 2015, 162, 108-119
33.7738Citations (PDF)
86High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila
Molecular Cell, 2015, 60, 146-162
13.384Citations (PDF)
87Long-Range Chromatin Interactions7.2258Citations (PDF)
88The yeast genome undergoes significant topological reorganization in quiescence
Nucleic Acids Research, 2015, 43, 8299-8313
15.581Citations (PDF)
89Chromosome Conformation Capture (3C) in Budding Yeast
Cold Spring Harbor Protocols, 2015, 2015, pdb.prot085175
0.312Citations (PDF)
90Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells
Cell, 2015, 163, 134-147
33.7476Citations (PDF)
91Structural and functional diversity of Topologically Associating Domains
FEBS Letters, 2015, 589, 2877-2884
2.7313Citations (PDF)
92The Hitchhiker’s guide to Hi-C analysis: Practical guidelines
Methods, 2015, 72, 65-75
3.5406Citations (PDF)
93Two ways to fold the genome during the cell cycle: insights obtained with chromosome conformation capture3.273Citations (PDF)
94Predictive Polymer Modeling Reveals Coupled Fluctuations in Chromosome Conformation and Transcription
Cell, 2014, 157, 950-963
33.7451Citations (PDF)
95Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
Nature, 2014, 516, 432-435
37.9289Citations (PDF)
96Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease7.525Citations (PDF)
97Segmental folding of chromosomes: A basis for structural and regulatory chromosomal neighborhoods?
BioEssays, 2013, 35, 818-828
2.1172Citations (PDF)
98Organization of the Mitotic Chromosome
Science, 2013, 342, 948-953
36.21,027Citations (PDF)
99Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments
Genome Research, 2013, 23, 2066-2077
4.6299Citations (PDF)
100Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny
Genes and Development, 2013, 27, 2439-2444
4.647Citations (PDF)
101High-throughput genome scaffolding from in vivo DNA interaction frequency
Nature Biotechnology, 2013, 31, 1143-1147
29.8197Citations (PDF)
102Correlated alterations in genome organization, histone methylation, and DNA–lamin A/C interactions in Hutchinson-Gilford progeria syndrome
Genome Research, 2013, 23, 260-269
4.6307Citations (PDF)
103The Hierarchy of the 3D Genome
Molecular Cell, 2013, 49, 773-782
13.3693Citations (PDF)
104Nuclear Biology: What’s Been Most Surprising?
Cell, 2013, 152, 1207-1208
33.73Citations (PDF)
105Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data
Nature Reviews Genetics, 2013, 14, 390-403
47.01,052Citations (PDF)
106Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
Cell, 2013, 153, 1281-1295
33.71,160Citations (PDF)
107HiTC: exploration of high-throughput ‘C’ experiments
Bioinformatics, 2012, 28, 2843-2844
4.7198Citations (PDF)
108An encyclopedia of mouse DNA elements (Mouse ENCODE)
Genome Biology, 2012, 13,
8.1437Citations (PDF)
109Hi–C: A comprehensive technique to capture the conformation of genomes
Methods, 2012, 58, 268-276
3.51,142Citations (PDF)
110From cells to chromatin: Capturing snapshots of genome organization with 5C technology
Methods, 2012, 58, 255-267
3.544Citations (PDF)
111Analysis of long-range chromatin interactions using Chromosome Conformation Capture
Methods, 2012, 58, 192-203
3.5154Citations (PDF)
112The long-range interaction landscape of gene promoters
Nature, 2012, 489, 109-113
37.91,420Citations (PDF)
113Spatial Organization of the Mouse Genome and Its Role in Recurrent Chromosomal Translocations
Cell, 2012, 148, 908-921
33.7523Citations (PDF)
114Iterative correction of Hi-C data reveals hallmarks of chromosome organization
Nature Methods, 2012, 9, 999-1003
24.61,420Citations (PDF)
115The accessible chromatin landscape of the human genome
Nature, 2012, 489, 75-82
37.92,636Citations (PDF)
116Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells
PLoS ONE, 2012, 7, e28213
2.362Citations (PDF)
117The context of gene expression regulation2.224Citations (PDF)
118Spatial partitioning of the regulatory landscape of the X-inactivation centre
Nature, 2012, 485, 381-385
37.92,977Citations (PDF)
119Enhanced yeast one-hybrid assays for high-throughput gene-centered regulatory network mapping
Nature Methods, 2011, 8, 1059-1064
24.6134Citations (PDF)
120The Three-Dimensional Architecture of a Bacterial Genome and Its Alteration by Genetic Perturbation
Molecular Cell, 2011, 44, 252-264
13.3267Citations (PDF)
121A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
Nature, 2011, 472, 120-124
37.91,883Citations (PDF)
122Chromatin globules: a common motif of higher order chromosome structure?3.965Citations (PDF)
123Yeast one-hybrid assays for gene-centered human gene regulatory network mapping
Nature Methods, 2011, 8, 1050-1052
24.651Citations (PDF)
124Integrating Structural and Functional Studies Leads to a New Model of β-Globin Activation That Suggests Distinct Initiation and Maintenance States
Blood, 2011, 118, 349-349
4.20Citations (PDF)
125Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.0.3359Citations (PDF)
126Mediator and cohesin connect gene expression and chromatin architecture
Nature, 2010, 467, 430-435
37.91,846Citations (PDF)
127Genomics tools for unraveling chromosome architecture
Nature Biotechnology, 2010, 28, 1089-1095
29.8210Citations (PDF)
128Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene
Nucleic Acids Research, 2010, 38, 4325-4336
15.5101Citations (PDF)
129Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease7.5195Citations (PDF)
130Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination
Cell, 2010, 143, 924-937
33.7274Citations (PDF)
131Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening
PLoS Genetics, 2009, 5, e1000522
3.285Citations (PDF)
132Gene dates, parties and galas
EMBO Reports, 2009, 10, 689-693
5.23Citations (PDF)
133My5C: web tools for chromosome conformation capture studies
Nature Methods, 2009, 6, 690-691
24.687Citations (PDF)
134Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
Science, 2009, 326, 289-293
36.28,581Citations (PDF)
135Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery
Genes and Development, 2009, 23, 912-927
4.6304Citations (PDF)
136Yeast Silent Mating Type Loci Form Heterochromatic Clusters through Silencer Protein-Dependent Long-Range Interactions
PLoS Genetics, 2009, 5, e1000478
3.294Citations (PDF)
137A mechanism for Ikaros regulation of human globin gene switching
British Journal of Haematology, 2008, 141, 398-406
2.736Citations (PDF)
138Mapping in Vivo Chromatin Interactions in Yeast Suggests an Extended Chromatin Fiber with Regional Variation in Compaction
Journal of Biological Chemistry, 2008, 283, 34532-34540
2.2147Citations (PDF)
139Chromosome Conformation Capture Carbon Copy Technology0.040Citations (PDF)
140GC- and AT-rich chromatin domains differ in conformation and histone modification status and are differentially modulated by Rpd3p
Genome Biology, 2007, 8, R116
12.267Citations (PDF)
141Polycomb response elements mediate the formation of chromosome higher-order structures in the bithorax complex
Nature Cell Biology, 2007, 9, 1167-1174
16.3277Citations (PDF)
142Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
Nature, 2007, 447, 799-816
37.94,877Citations (PDF)
143Ikaros Drives Human Haemoglobin Switching by Facilitating Active Chromatin Hub Formation.
Blood, 2007, 110, 1772-1772
4.20Citations (PDF)
144Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
Genome Research, 2006, 16, 1299-1309
4.61,110Citations (PDF)
145The active FMR1 promoter is associated with a large domain of altered chromatin conformation with embedded local histone modifications7.552Citations (PDF)
146Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1
Molecular Cell, 2005, 17, 453-462
13.3467Citations (PDF)
147A mechanical basis for chromosome function7.5306Citations (PDF)
148A closer look at long-range chromosomal interactions6.757Citations (PDF)
149Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p
Genes and Development, 2000, 14, 493-503
4.6215Citations (PDF)
150ATP-independent DNA unwinding by the adenovirus single-stranded DNA binding protein requires a flexible DNA binding loop 1 1Edited by M. Yaniv
Journal of Molecular Biology, 1998, 277, 825-838
4.123Citations (PDF)
151Multimerization of the adenovirus DNA-binding protein is the driving force for ATP-independent DNA unwinding during strand displacement synthesis
EMBO Journal, 1997, 16, 1455-1463
7.347Citations (PDF)
152Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization
ELife, 0, 10,
1.644Citations (PDF)
153Large domains of heterochromatin direct the formation of short mitotic chromosome loops
ELife, 0, 9,
1.612Citations (PDF)
154Mitotic chromosomes scale to nuclear-cytoplasmic ratio and cell size in Xenopus
ELife, 0, 12,
1.617Citations (PDF)
155mRNA initiation and termination are spatially coordinated
Science, 0, 390,
36.24Citations (PDF)
156An integrated view of the structure and function of the human 4D nucleome
Nature, 0, 649, 759-776
37.92Citations (PDF)
157Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm
Nature Cell Biology, 0, 28, 82-97
16.33Citations (PDF)