184(top 100%)
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35.5K(top 1%)
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187 PR articles • 38,567 PR citations • Sorted by year • Download PDF (PDF by citations)
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1Mitochondrial ATP generation is more proteome efficient than glycolysis
Nature Chemical Biology, 2024, 20, 1123-1132
12.089Citations (PDF)
2A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting
Nature Microbiology, 2024, 9, 1207-1219
16.517Citations (PDF)
3Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer13.928Citations (PDF)
4Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Science, 2024, 385,
36.4136Citations (PDF)
5Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics
Nature Cardiovascular Research, 2024, 3, 1236-1248
8.88Citations (PDF)
6Slow TCA flux and ATP production in primary solid tumours but not metastases
Nature, 2023, 614, 349-357
38.7253Citations (PDF)
7Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance
Nature Metabolism, 2023, 5, 589-606
17.740Citations (PDF)
8A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression
Nature Cancer, 2023, 4, 682-698
22.828Citations (PDF)
9The pentose phosphate pathway in health and disease
Nature Metabolism, 2023, 5, 1275-1289
17.7401Citations (PDF)
10An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis13.959Citations (PDF)
11Acidic Methanol Treatment Facilitates Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry Imaging of Energy Metabolism
Analytical Chemistry, 2023, 95, 14879-14888
6.524Citations (PDF)
12Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade
Cancer Discovery, 2023, 13, 2566-2583
25.639Citations (PDF)
13Metabolic pathway analysis using stable isotopes in patients with cancer
Nature Reviews Cancer, 2023, 23, 863-878
61.853Citations (PDF)
14Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
Molecular Cancer Research, 2022, 18, 599-611
3.272Citations (PDF)
15GCN2 adapts protein synthesis to scavenging-dependent growth
Cell Systems, 2022, 13, 158-172.e9
5.830Citations (PDF)
16Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
Cell Chemical Biology, 2022, 29, 423-435.e10
6.259Citations (PDF)
17SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma
Blood, 2022, 139, 538-553
4.240Citations (PDF)
18MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
Immunity, 2022, 55, 65-81.e9
23.3175Citations (PDF)
19Circulating metabolite homeostasis achieved through mass action
Nature Metabolism, 2022, 4, 141-152
17.749Citations (PDF)
20Sex and genetic background define the metabolic, physiologic, and molecular response to protein restriction
Cell Metabolism, 2022, 34, 209-226.e5
26.2101Citations (PDF)
21Spatially resolved isotope tracing reveals tissue metabolic activity
Nature Methods, 2022, 19, 223-230
25.9161Citations (PDF)
22Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
Med, 2022, 3, 119-136.e8
7.387Citations (PDF)
23G6PD-mediated increase in de novo NADP <sup>+</sup> biosynthesis promotes antioxidant defense and tumor metastasis
Science Advances, 2022, 8,
11.048Citations (PDF)
24Glucose feeds the tricarboxylic acid cycle via excreted ethanol in fermenting yeast
Nature Chemical Biology, 2022, 18, 1380-1387
12.035Citations (PDF)
25Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate
Cancer Research, 2022, 82, 3486-3498
0.631Citations (PDF)
26Gut bacterial nutrient preferences quantified in vivo
Cell, 2022, 185, 3441-3456.e19
34.1160Citations (PDF)
27Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport15.041Citations (PDF)
28Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation
Cell Metabolism, 2021, 33, 94-109.e8
26.280Citations (PDF)
29Inhibition of <i>de novo</i> pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer8.810Citations (PDF)
30Restoring metabolism of myeloid cells reverses cognitive decline in ageing
Nature, 2021, 590, 122-128
38.7416Citations (PDF)
31The Source of Glycolytic Intermediates in Mammalian Tissues
Cell Metabolism, 2021, 33, 367-378.e5
26.2115Citations (PDF)
32The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
Cell Metabolism, 2021, 33, 905-922.e6
26.2339Citations (PDF)
33Monitoring mammalian mitochondrial translation with MitoRiboSeq
Nature Protocols, 2021, 16, 2802-2825
14.532Citations (PDF)
34mTORC1 promotes cell growth via m6A-dependent mRNA degradation
Molecular Cell, 2021, 81, 2064-2075.e8
13.493Citations (PDF)
35Live-Cell Imaging of NADPH Production from Specific Pathways
CCS Chemistry, 2021, 3, 1642-1648
8.711Citations (PDF)
36Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer
Med, 2021, 2, 736-754.e6
7.352Citations (PDF)
37NAD+ flux is maintained in aged mice despite lower tissue concentrations
Cell Systems, 2021, 12, 1160-1172.e4
5.896Citations (PDF)
38A genetic model of methionine restriction extends <i>Drosophila</i> health- and lifespan7.640Citations (PDF)
39CAR T-Cells Depend on the Coupling of NADH Oxidation with ATP Production
Cells, 2021, 10, 2334
4.811Citations (PDF)
40Metabolite discovery through global annotation of untargeted metabolomics data
Nature Methods, 2021, 18, 1377-1385
25.9212Citations (PDF)
41Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition
Science Advances, 2021, 7,
11.077Citations (PDF)
42Serine catabolism generates liver NADPH and supports hepatic lipogenesis
Nature Metabolism, 2021, 3, 1608-1620
17.7101Citations (PDF)
43Methionine synthase supports tumour tetrahydrofolate pools
Nature Metabolism, 2021, 3, 1512-1520
17.753Citations (PDF)
44Elevated Choline Kinase α–Mediated Choline Metabolism Supports the Prolonged Survival of TRAF3-Deficient B Lymphocytes
Journal of Immunology, 2020, 204, 459-471
0.617Citations (PDF)
45Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia
Cell Reports, 2020, 32, 108170
6.411Citations (PDF)
46Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis
Cancer Research, 2020, 80, 3820-3829
0.642Citations (PDF)
47CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels
Nature Metabolism, 2020, 2, 1284-1304
17.7286Citations (PDF)
48SLC25A51 is a mammalian mitochondrial NAD+ transporter
Nature, 2020, 588, 174-179
38.7267Citations (PDF)
49Enhancing Chimeric Antigen Receptor T Cell Anti-tumor Function through Advanced Media Design4.158Citations (PDF)
50Quantitative Fluxomics of Circulating Metabolites
Cell Metabolism, 2020, 32, 676-688.e4
26.2257Citations (PDF)
51Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells
Science, 2020, 369, 397-403
36.491Citations (PDF)
52The hepatocyte clock and feeding control chronophysiology of multiple liver cell types
Science, 2020, 369, 1388-1394
36.4157Citations (PDF)
53Metabolic excretion associated with nutrient–growth dysregulation promotes the rapid evolution of an overt metabolic defect
PLoS Biology, 2020, 18, e3000757
5.020Citations (PDF)
54Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response
Nature Cancer, 2020, 1, 923-934
22.8110Citations (PDF)
55Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
Cell, 2020, 183, 1848-1866.e26
34.1611Citations (PDF)
56Genome-scale metabolic reconstruction of the non-model yeast Issatchenkia orientalis SD108 and its application to organic acids production3.933Citations (PDF)
57A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
Nature Chemical Biology, 2020, 16, 731-739
12.0170Citations (PDF)
58A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
Cell, 2020, 181, 1518-1532.e14
34.1320Citations (PDF)
59Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
Nature, 2020, 579, 586-591
38.7473Citations (PDF)
60Serine Catabolism Feeds NADH when Respiration Is Impaired
Cell Metabolism, 2020, 31, 809-821.e6
26.2182Citations (PDF)
61Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 <sup>+</sup> T cell stemness and antitumor immunity7.6202Citations (PDF)
62Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity
Analytical Chemistry, 2020, 92, 11573-11581
6.524Citations (PDF)
63SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia
Leukemia, 2020, 35, 377-388
10.4114Citations (PDF)
64Novel Pyrrolo[3,2-<i>d</i>]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy
Molecular Cancer Therapeutics, 2019, 18, 1787-1799
1.850Citations (PDF)
65Metabolite Exchange between Mammalian Organs Quantified in Pigs
Cell Metabolism, 2019, 30, 594-606.e3
26.2242Citations (PDF)
66Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity
Nature Immunology, 2019, 20, 1023-1034
24.2145Citations (PDF)
67Natural human genetic variation determines basal and inducible expression of <i>PM20D1</i> , an obesity-associated gene7.641Citations (PDF)
68A comprehensive genome-scale model for Rhodosporidium toruloides IFO0880 accounting for functional genomics and phenotypic data3.974Citations (PDF)
69PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism
Cell Stem Cell, 2019, 25, 830-845.e8
16.899Citations (PDF)
70Near-equilibrium glycolysis supports metabolic homeostasis and energy yield
Nature Chemical Biology, 2019, 15, 1001-1008
12.086Citations (PDF)
71The Tumor Metabolic Microenvironment: Lessons from Lactate
Cancer Research, 2019, 79, 3155-3162
0.6214Citations (PDF)
72A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate
Cell Metabolism, 2019, 30, 174-189.e5
26.2200Citations (PDF)
73The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled)13.963Citations (PDF)
74A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism
Cell Reports, 2019, 27, 3359-3370.e7
6.442Citations (PDF)
75NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism
Nature Metabolism, 2019, 1, 404-415
17.7346Citations (PDF)
76Minor Isozymes Tailor Yeast Metabolism to Carbon Availability
MSystems, 2019, 4,
4.517Citations (PDF)
77Serine Metabolism Supports Macrophage IL-1β Production
Cell Metabolism, 2019, 29, 1003-1011.e4
26.2317Citations (PDF)
78Peak Annotation and Verification Engine for Untargeted LC–MS Metabolomics
Analytical Chemistry, 2019, 91, 1838-1846
6.5110Citations (PDF)
79Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids
Cell Metabolism, 2019, 29, 417-429.e4
26.2461Citations (PDF)
80Quantitative Survey of NAD + Flux in Aged Mice
FASEB Journal, 2019, 33,
0.70Citations (PDF)
81The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids
Cell Metabolism, 2018, 27, 351-361.e3
26.2569Citations (PDF)
82Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and <scp>DNA</scp> methylation in the brain
Journal of Neurochemistry, 2018, 145, 362-373
3.931Citations (PDF)
83As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
Cell Metabolism, 2018, 27, 428-438.e5
26.2309Citations (PDF)
84Metabolomics and Isotope Tracing
Cell, 2018, 173, 822-837
34.1747Citations (PDF)
85Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
Cell Metabolism, 2018, 27, 1067-1080.e5
26.2503Citations (PDF)
86Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors6.5183Citations (PDF)
87Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase
ACS Chemical Biology, 2018, 13, 3011-3020
3.715Citations (PDF)
88Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR2.44Citations (PDF)
895,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination1.424Citations (PDF)
90Four Key Steps Control Glycolytic Flux in Mammalian Cells
Cell Systems, 2018, 7, 49-62.e8
5.8347Citations (PDF)
91Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes
Cell, 2018, 174, 831-842.e12
34.1200Citations (PDF)
92Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation
Nature Immunology, 2018, 20, 50-63
24.2441Citations (PDF)
93Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice
Journal of Clinical Investigation, 2018, 128, 2226-2238
10.7113Citations (PDF)
94Metabolite Spectral Accuracy on Orbitraps
Analytical Chemistry, 2017, 89, 5940-5948
6.5280Citations (PDF)
95Treatment of Pancreatic Cancer Patient–Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin
Clinical Cancer Research, 2017, 23, 5639-5647
6.987Citations (PDF)
96Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma7.6237Citations (PDF)
97An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate3.550Citations (PDF)
98Chemical Basis for Deuterium Labeling of Fat and NADPH15.094Citations (PDF)
99Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
Cancer Cell, 2017, 32, 377-391.e9
38.5580Citations (PDF)
100mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
Molecular Cell, 2017, 67, 936-946.e5
13.497Citations (PDF)
101A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles
Cancer Discovery, 2017, 7, 1266-1283
25.6197Citations (PDF)
102PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy
Circulation Research, 2017, 121, 1370-1378
12.546Citations (PDF)
103Dynamic Control of dNTP Synthesis in Early Embryos
Developmental Cell, 2017, 42, 301-308.e3
7.840Citations (PDF)
104Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate
Nature Chemical Biology, 2017, 13, 1081-1087
12.071Citations (PDF)
105Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling
Cell, 2017, 171, 1545-1558.e18
34.1194Citations (PDF)
106Metabolite Measurement: Pitfalls to Avoid and Practices to Follow17.7421Citations (PDF)
107One-Carbon Metabolism in Health and Disease
Cell Metabolism, 2017, 25, 27-42
26.21,850Citations (PDF)
108A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae
PLoS ONE, 2017, 12, e0176085
2.434Citations (PDF)
109Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation
Cell Metabolism, 2016, 24, 104-117
26.2391Citations (PDF)
110Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway
Cell Metabolism, 2016, 23, 1140-1153
26.2373Citations (PDF)
111Metabolite concentrations, fluxes and free energies imply efficient enzyme usage
Nature Chemical Biology, 2016, 12, 482-489
12.0442Citations (PDF)
112Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle
Cell Metabolism, 2016, 24, 269-282
26.2346Citations (PDF)
113Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
Genes and Development, 2016, 30, 1704-1717
4.7346Citations (PDF)
114Glucose becomes one of the worst carbon sources for E.coli on poor nitrogen sources due to suboptimal levels of cAMP3.5134Citations (PDF)
115Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP
Cell Metabolism, 2016, 24, 863-874
26.273Citations (PDF)
116Systems-level analysis of mechanisms regulating yeast metabolic flux
Science, 2016, 354,
36.4291Citations (PDF)
117Metabolic control of methylation and acetylation5.9280Citations (PDF)
118Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
Nature Chemical Biology, 2016, 12, 345-352
12.0130Citations (PDF)
119Mitochondria and Cancer
Molecular Cell, 2016, 61, 667-676
13.41,101Citations (PDF)
120Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
Cancer Research, 2015, 75, 544-553
0.6818Citations (PDF)
121Avoiding Misannotation of In-Source Fragmentation Products as Cellular Metabolites in Liquid Chromatography–Mass Spectrometry-Based Metabolomics
Analytical Chemistry, 2015, 87, 2273-2281
6.5196Citations (PDF)
122Hierarchy in Pentose Sugar Metabolism in Clostridium acetobutylicum3.542Citations (PDF)
123A roadmap for interpreting 13 C metabolite labeling patterns from cells6.9607Citations (PDF)
124Characterizing the in vivo role of trehalose in<i>Saccharomyces cerevisiae</i>using the<i>AGT1</i>transporter7.692Citations (PDF)
125Fatty Acid Elongase 7 Catalyzes Lipidome Remodeling Essential for Human Cytomegalovirus Replication
Cell Reports, 2015, 10, 1375-1385
6.495Citations (PDF)
126Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation
Cell Metabolism, 2015, 22, 1068-1077
26.2237Citations (PDF)
127RNA Futile Cycling in Model Persisters Derived from MazF Accumulation
MBio, 2015, 6,
4.458Citations (PDF)
128The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Biological Reviews, 2015, 90, 927-963
11.51,324Citations (PDF)
129Genetic Basis of Metabolome Variation in Yeast
PLoS Genetics, 2014, 10, e1004142
3.355Citations (PDF)
130Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
Cancer Discovery, 2014, 4, 1406-1417
25.6401Citations (PDF)
131Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance
Cancer Discovery, 2014, 4, 914-927
25.6523Citations (PDF)
132Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion
Molecular Cell, 2014, 56, 205-218
13.4427Citations (PDF)
133Functional Role of Autophagy-Mediated Proteome Remodeling in Cell Survival Signaling and Innate Immunity
Molecular Cell, 2014, 55, 916-930
13.4115Citations (PDF)
134Enzyme clustering accelerates processing of intermediates through metabolic channeling
Nature Biotechnology, 2014, 32, 1011-1018
32.2418Citations (PDF)
135Quantitation of Cellular Metabolic Fluxes of Methionine
Analytical Chemistry, 2014, 86, 1583-1591
6.546Citations (PDF)
136Chemical Genetics of Rapamycin-Insensitive TORC2 in S. cerevisiae
Cell Reports, 2013, 5, 1725-1736
6.435Citations (PDF)
137Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides
Chemistry and Biology, 2013, 20, 1386-1398
4.825Citations (PDF)
138Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis
Genes and Development, 2013, 27, 1447-1461
4.7573Citations (PDF)
139Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia6.7398Citations (PDF)
140Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids7.6690Citations (PDF)
141Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase
Nature Chemical Biology, 2012, 8, 562-568
12.079Citations (PDF)
142Regulation of Yeast Pyruvate Kinase by Ultrasensitive Allostery Independent of Phosphorylation
Molecular Cell, 2012, 48, 52-62
13.469Citations (PDF)
143LC‐MS Data Processing with MAVEN: A Metabolomic Analysis and Visualization Engine3.3471Citations (PDF)
144α-ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition
Nature Chemical Biology, 2011, 7, 894-901
12.0240Citations (PDF)
145Riboneogenesis in Yeast
Cell, 2011, 145, 969-980
34.1120Citations (PDF)
146Liquid Chromatography–High Resolution Mass Spectrometry Analysis of Fatty Acid Metabolism
Analytical Chemistry, 2011, 83, 9114-9122
6.589Citations (PDF)
147Robust Control of Nitrogen Assimilation by a Bifunctional Enzyme in E. coli
Molecular Cell, 2011, 41, 117-127
13.456Citations (PDF)
148Metabolome Remodeling during the Acidogenic-Solventogenic Transition in Clostridium acetobutylicum3.5119Citations (PDF)
149Metabolomics in systems microbiology6.9113Citations (PDF)
150Yeast cells can access distinct quiescent states
Genes and Development, 2011, 25, 336-349
4.7163Citations (PDF)
151Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function7.6101Citations (PDF)
152Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Genes and Development, 2011, 25, 460-470
4.71,205Citations (PDF)
153Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism
PLoS Pathogens, 2011, 7, e1002124
4.4327Citations (PDF)
154Remodeling of the Metabolome during Early Frog Development
PLoS ONE, 2011, 6, e16881
2.461Citations (PDF)
155Enhancing molecular discovery using descriptor‐free rearrangement clustering techniques for sparse data sets
AICHE Journal, 2010, 56, 405-418
3.74Citations (PDF)
156Metabolomic Analysis via Reversed-Phase Ion-Pairing Liquid Chromatography Coupled to a Stand Alone Orbitrap Mass Spectrometer
Analytical Chemistry, 2010, 82, 3212-3221
6.5485Citations (PDF)
157The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Cancer Cell, 2010, 17, 225-234
38.51,922Citations (PDF)
158Growth-limiting Intracellular Metabolites in Yeast Growing under Diverse Nutrient Limitations2.5242Citations (PDF)
159Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in <i>Clostridium acetobutylicum</i>
Journal of Bacteriology, 2010, 192, 4452-4461
2.9126Citations (PDF)
160Quiescent Fibroblasts Exhibit High Metabolic Activity
PLoS Biology, 2010, 8, e1000514
5.0362Citations (PDF)
161Achieving Optimal Growth through Product Feedback Inhibition in Metabolism
PLoS Computational Biology, 2010, 6, e1000802
3.144Citations (PDF)
162Autophagy and Metabolism
Science, 2010, 330, 1344-1348
36.41,829Citations (PDF)
163Metabolomic Analysis and Visualization Engine for LC−MS Data
Analytical Chemistry, 2010, 82, 9818-9826
6.5667Citations (PDF)
164Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Nature, 2009, 462, 739-744
38.73,759Citations (PDF)
165Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
Nature Chemical Biology, 2009, 5, 593-599
12.01,794Citations (PDF)
166Metabolomics‐driven quantitative analysis of ammonia assimilation in <i>E. coli</i>6.7182Citations (PDF)
167Analytical strategies for LC–MS-based targeted metabolomics2.6443Citations (PDF)
168Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
Nature Biotechnology, 2008, 26, 1179-1186
32.2607Citations (PDF)
169A domino effect in antifolate drug action in Escherichia coli
Nature Chemical Biology, 2008, 4, 602-608
12.0114Citations (PDF)
170Dissecting Enzyme Regulation by Multiple Allosteric Effectors: Nucleotide Regulation of Aspartate Transcarbamoylase
Biochemistry, 2008, 47, 5881-5888
2.417Citations (PDF)
171OPTIMAL METHODS FOR RE-ORDERING DATA MATRICES IN SYSTEMS BIOLOGY AND DRUG DISCOVERY APPLICATIONS0.91Citations (PDF)
172Quorum Sensing Controls Biofilm Formation in <i>Vibrio cholerae</i> through Modulation of Cyclic Di-GMP Levels and Repression of <i>vpsT</i>
Journal of Bacteriology, 2008, 190, 2527-2536
2.9427Citations (PDF)
173A network flow model for biclustering via optimal re-ordering of data matrices1.212Citations (PDF)
174Acidic Acetonitrile for Cellular Metabolome Extraction from<i>Escherichia coli</i>
Analytical Chemistry, 2007, 79, 6167-6173
6.5332Citations (PDF)
175Cellular metabolomics ofEscherchia coli
Expert Review of Proteomics, 2007, 4, 187-198
2.166Citations (PDF)
176Isotope ratio-based profiling of microbial folates2.653Citations (PDF)
177Kinetic flux profiling of nitrogen assimilation in Escherichia coli
2006, 2, 529-530
121Citations (PDF)
178Identifying decomposition products in extracts of cellular metabolites
Analytical Biochemistry, 2006, 358, 273-280
2.476Citations (PDF)
179Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry
Journal of Chromatography A, 2006, 1125, 76-88
3.7554Citations (PDF)
180A high-performance liquid chromatography-tandem mass spectrometry method for quantitation of nitrogen-containing intracellular metabolites2.6122Citations (PDF)
181Ultra-Fast Absorption of Amorphous Pure Drug Aerosols via Deep Lung Inhalation3.257Citations (PDF)
182Ammonium Toxicity and Potassium Limitation in Yeast
PLoS Biology, 2006, 4, e351
5.0140Citations (PDF)
183Conservation of the metabolomic response to starvation across two divergent microbes7.6256Citations (PDF)
184Fast Onset Medications through Thermally Generated Aerosols3.372Citations (PDF)
185Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
ELife, 0, 7,
1.6131Citations (PDF)
186Partners in the Warburg effect
ELife, 0, 5,
1.610Citations (PDF)
187Downregulation of the tyrosine degradation pathway extends Drosophila lifespan
ELife, 0, 9,
1.646Citations (PDF)