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544 peer-reviewed articles • 34,015 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations22.469Citations (PDF)
2Insights into the Activation and Self-Association of Arrestin-1
Biochemistry, 2025, 64, 364-376
2.41Citations (PDF)
3CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3
Open Biology, 2025, 15,
3.21Citations (PDF)
4Structure and self-association of Arrestin-12.30Citations (PDF)
5Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction7.517Citations (PDF)
6MFRP is a molecular hub that organizes the apical membrane of RPE cells by engaging in interactions with specific proteins and lipids7.54Citations (PDF)
7Rationally Designed, Short-Acting RPE65 Inhibitors for Visual Cycle-Associated Retinopathies
Journal of Medicinal Chemistry, 2025, 68, 17638-17652
5.63Citations (PDF)
8TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches7.55Citations (PDF)
9Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice2.67Citations (PDF)
10Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins2.210Citations (PDF)
11Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Nature Biotechnology, 2024, 42, 1526-1537
29.8227Citations (PDF)
12Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice2.29Citations (PDF)
13Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors
Cell Reports, 2024, 43, 114143
6.312Citations (PDF)
14Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration2.24Citations (PDF)
15A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models13.720Citations (PDF)
16Ultrafast transient absorption spectra and kinetics of human blue cone visual pigment at room temperature7.54Citations (PDF)
17Retinal Proteome Profiling of Inherited Retinal Degeneration Across Three Different Mouse Models Suggests Common Drug Targets in Retinitis Pigmentosa3.015Citations (PDF)
18In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice7.517Citations (PDF)
19Structural view of G protein-coupled receptor signaling in the retinal rod outer segment6.726Citations (PDF)
20Ultrafast spectra and kinetics of human green-cone visual pigment at room temperature7.58Citations (PDF)
21Genome editing, a superior therapy for inherited retinal diseases
Vision Research, 2023, 206, 108192
1.237Citations (PDF)
22In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope
STAR Protocols, 2023, 4, 102225
1.16Citations (PDF)
23From mouse to human: Accessing the biochemistry of vision in vivo by two-photon excitation12.916Citations (PDF)
24Investigating the Role of RhodopsinF45LMutation in Mouse Rod Photoreceptor Signaling and Survival
ENeuro, 2023, 10, ENEURO.0330-22.2023
2.12Citations (PDF)
25Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition7.516Citations (PDF)
26A short story on how chromophore is hydrolyzed from rhodopsin for recycling
BioEssays, 2023, 45,
2.110Citations (PDF)
27Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
Cell Reports, 2023, 42, 112982
6.339Citations (PDF)
28Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain13.721Citations (PDF)
29Genome editing in the treatment of ocular diseases11.343Citations (PDF)
30Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses7.511Citations (PDF)
31Structural evidence for visual arrestin priming via complexation of phosphoinositols
Structure, 2022, 30, 263-277.e5
3.824Citations (PDF)
32A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype
Human Molecular Genetics, 2022, 31, 1263-1277
2.919Citations (PDF)
33MicroRNA regulation of critical retinal pigment epithelial functions
Trends in Neurosciences, 2022, 45, 78-90
9.828Citations (PDF)
34In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope10.644Citations (PDF)
35Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision
JCI Insight, 2022, 7,
5.442Citations (PDF)
36Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
Cell, 2022, 185, 250-265.e16
33.6616Citations (PDF)
37VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy6.421Citations (PDF)
38Capturing a rhodopsin receptor signalling cascade across a native membrane
Nature, 2022, 604, 384-390
37.981Citations (PDF)
39In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration13.792Citations (PDF)
40Regenerating Skeletal Muscle Compensates for the Impaired Macrophage Functions Leading to Normal Muscle Repair in Retinol Saturase Null Mice
Cells, 2022, 11, 1333
4.66Citations (PDF)
41Stabilization of Meta‐I Rhodopsin Conformation by a Nanobody
FASEB Journal, 2022, 36,
0.60Citations (PDF)
42Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice
ENeuro, 2022, 9, ENEURO.0107-22.2022
2.115Citations (PDF)
43Deletion of Protein Phosphatase 2A Accelerates Retinal Degeneration in GRK1- and Arr1-Deficient Mice
2022, 63, 18
2Citations (PDF)
44Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes7.524Citations (PDF)
45Retinoids in the visual cycle: role of the retinal G protein-coupled receptor
Journal of Lipid Research, 2021, 62, 100040
3.661Citations (PDF)
46Pathways and disease-causing alterations in visual chromophore production for vertebrate vision2.249Citations (PDF)
47Formulation and efficacy of ECO/pRHO-ABCA4-SV40 nanoparticles for nonviral gene therapy of Stargardt disease in a mouse model
Journal of Controlled Release, 2021, 330, 329-340
11.024Citations (PDF)
48An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease
JCI Insight, 2021, 6,
5.422Citations (PDF)
49Peptide Derivatives of Retinylamine Prevent Retinal Degeneration with Minimal Side Effects on Vision in Mice
Bioconjugate Chemistry, 2021, 32, 572-583
3.87Citations (PDF)
50A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-63.346Citations (PDF)
51Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy
Journal of Medicinal Chemistry, 2021, 64, 8287-8302
5.618Citations (PDF)
52Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition5.437Citations (PDF)
53Regulation of Adrenergic, Serotonin, and Dopamine Receptors to Inhibit Diabetic Retinopathy: Monotherapies versus Combination Therapies
Molecular Pharmacology, 2021, 100, 470-479
2.615Citations (PDF)
54New focus on regulation of the rod photoreceptor phosphodiesterase6.48Citations (PDF)
55Theoretical Study of the Photoisomerization Mechanism of All-Trans-Retinyl Acetate
Journal of Physical Chemistry A, 2021, 125, 8358-8372
2.54Citations (PDF)
56Function of mammalian M-cones depends on the level of CRALBP in Müller cells2.419Citations (PDF)
57Two-photon microperimetry with picosecond pulses2.816Citations (PDF)
58THE LOSS OF INFRARED LIGHT SENSITIVITY OF PHOTORECEPTOR CELLS MEASURED WITH TWO-PHOTON EXCITATION AS AN INDICATOR OF DIABETIC RETINOPATHY
Retina, 2021, 41, 1302-1308
1.816Citations (PDF)
59Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization2.27Citations (PDF)
60Straightforward Access to Terminally Disubstituted Electron‐Deficient Alkylidene Cyclopent‐2‐en‐4‐ones through Olefination with α‐Carbonyl and α‐Cyano Secondary Alkyl Sulfones2.31Citations (PDF)
61Non-viral Gene Therapy for Stargardt Disease with ECO/pRHO-ABCA4 Self-Assembled Nanoparticles
Molecular Therapy, 2020, 28, 293-303
10.248Citations (PDF)
62Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases2.02Citations (PDF)
63Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model
Human Molecular Genetics, 2020, 29, 2611-2624
2.915Citations (PDF)
64Clinical Application of Infrared-Light Microperimetry in the Assessment of Scotopic-Eye Sensitivity2.216Citations (PDF)
65Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody
FASEB Journal, 2020, 34, 13918-13934
0.612Citations (PDF)
66Noninvasive two-photon optical biopsy of retinal fluorophores7.546Citations (PDF)
67PAR4 activation involves extracellular loop 3 and transmembrane residue Thr153
Blood, 2020, 136, 2217-2228
4.832Citations (PDF)
68PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation7.581Citations (PDF)
69Stable Retinoid Analogue Targeted Dual pH-Sensitive Smart Lipid ECO/pDNA Nanoparticles for Specific Gene Delivery in the Retinal Pigment Epithelium
ACS Applied Bio Materials, 2020, 3, 3078-3086
4.716Citations (PDF)
70Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation
PLoS ONE, 2020, 15, e0228121
2.310Citations (PDF)
71Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing22.4153Citations (PDF)
72Cryo-EM structure of the native rhodopsin dimer in nanodiscs
Journal of Biological Chemistry, 2019, 294, 14215-14230
2.285Citations (PDF)
73Tissue- and Species-Specific Patterns of RNA metabolism in Post-Mortem Mammalian Retina and Retinal Pigment Epithelium3.412Citations (PDF)
74Photic generation of 11-cis-retinal in bovine retinal pigment epithelium
Journal of Biological Chemistry, 2019, 294, 19137-19154
2.264Citations (PDF)
75Z-isomerization of retinoids through combination of monochromatic photoisomerization and metal catalysis2.613Citations (PDF)
76Sensitivity of Mammalian Cone Photoreceptors to Infrared Light
Neuroscience, 2019, 416, 100-108
2.314Citations (PDF)
77Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention
Pharmaceuticals, 2019, 12, 74
4.211Citations (PDF)
78Stereospecific modulation of dimeric rhodopsin
FASEB Journal, 2019, 33, 9526-9539
0.69Citations (PDF)
79Catalytic synthesis of 9-cis-retinoids: mechanistic insights
Dalton Transactions, 2019, 48, 10581-10595
3.06Citations (PDF)
80The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration
Journal of Biological Chemistry, 2019, 294, 9461-9475
2.217Citations (PDF)
81Transducin1, Phototransduction and the Development of Early Diabetic Retinopathy
2019, 60, 1538
61Citations (PDF)
82Cryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases
Science Advances, 2019, 5,
10.943Citations (PDF)
83A Mixture of U.S. Food and Drug Administration–Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness
2019, 60, 1442
16Citations (PDF)
84Human red and green cone opsins are O-glycosylated at an N-terminal Ser/Thr–rich domain conserved in vertebrates
Journal of Biological Chemistry, 2019, 294, 8123-8133
2.211Citations (PDF)
85Specificity of the chromophore-binding site in human cone opsins
Journal of Biological Chemistry, 2019, 294, 6082-6093
2.212Citations (PDF)
86Retinol Saturase Knock-Out Mice are Characterized by Impaired Clearance of Apoptotic Cells and Develop Mild Autoimmunity
Biomolecules, 2019, 9, 737
4.213Citations (PDF)
87Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State
Journal of Neuroscience, 2019, 39, 212-223
3.714Citations (PDF)
88Müller glia phagocytose dead photoreceptor cells in a mouse model of retinal degenerative disease
FASEB Journal, 2019, 33, 3680-3692
0.670Citations (PDF)
89Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones
FASEB Journal, 2019, 33, 5782-5792
0.626Citations (PDF)
90Two-photon microperimetry: sensitivity of human photoreceptors to infrared light2.829Citations (PDF)
91Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65
Human Molecular Genetics, 2018, 27, 2225-2243
2.939Citations (PDF)
92Retinal-chitosan Conjugates Effectively Deliver Active Chromophores to Retinal Photoreceptor Cells in Blind Mice and Dogs
Molecular Pharmacology, 2018, 93, 438-452
2.620Citations (PDF)
93Increasing the Stability of Recombinant Human Green Cone Pigment
Biochemistry, 2018, 57, 1022-1030
2.411Citations (PDF)
94Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function
Journal of General Physiology, 2018, 150, 571-590
2.432Citations (PDF)
95Structural biology of 11-cis-retinaldehyde production in the classical visual cycle
Biochemical Journal, 2018, 475, 3171-3188
3.825Citations (PDF)
96New GABA modulators protect photoreceptor cells from light‐induced degeneration in mouse models
FASEB Journal, 2018, 32, 3289-3300
0.616Citations (PDF)
97A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration13.765Citations (PDF)
98Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor13.775Citations (PDF)
99A Small Chaperone Improves Folding and Routing of Rhodopsin Mutants Linked to Inherited Blindness
IScience, 2018, 4, 1-19
3.562Citations (PDF)
100Exploring a new ligand binding site of G protein-coupled receptors
Chemical Science, 2018, 9, 6480-6489
7.143Citations (PDF)
101Protective Effect of a Locked Retinal Chromophore Analog against Light-Induced Retinal Degeneration
Molecular Pharmacology, 2018, 94, 1132-1144
2.622Citations (PDF)
102A Combination of G Protein–Coupled Receptor Modulators Protects Photoreceptors from Degeneration3.323Citations (PDF)
103Two-photon imaging of the mammalian retina with ultrafast pulsing laser
JCI Insight, 2018, 3,
5.429Citations (PDF)
104Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration
Human Molecular Genetics, 2017, , ddw387
2.941Citations (PDF)
105MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice
Journal of Biological Chemistry, 2017, 292, 3366-3378
2.233Citations (PDF)
106Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors
Biochemistry, 2017, 56, 2338-2348
2.49Citations (PDF)
107Structure and Spectroscopy of Alkene-Cleaving Dioxygenases Containing an Atypically Coordinated Non-Heme Iron Center
Biochemistry, 2017, 56, 2836-2852
2.437Citations (PDF)
108Rational Tuning of Visual Cycle Modulator Pharmacodynamics3.324Citations (PDF)
109Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber’s Congenital Amaurosis5.545Citations (PDF)
110Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism7.537Citations (PDF)
111Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium
Journal of Biological Chemistry, 2017, 292, 19826-19839
2.217Citations (PDF)
112Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors7.515Citations (PDF)
113Designing Safer Analgesics via μ-Opioid Receptor Pathways11.471Citations (PDF)
114Photoreceptor cells produce inflammatory products that contribute to retinal vascular permeability in a mouse model of diabetes
Diabetologia, 2017, 60, 2111-2120
7.575Citations (PDF)
115Crowd sourcing difficult problems in protein science<sup>*</sup>
Protein Science, 2017, 26, 2118-2125
5.91Citations (PDF)
116Complex binding pathways determine the regeneration of mammalian green cone opsin with a locked retinal analogue
Journal of Biological Chemistry, 2017, 292, 10983-10997
2.214Citations (PDF)
117The role of retinol dehydrogenase 10 in the cone visual cycle3.423Citations (PDF)
118A G Protein-Coupled Receptor Dimerization Interface in Human Cone Opsins
Biochemistry, 2017, 56, 61-72
2.425Citations (PDF)
119Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa
Pharmacological Research, 2017, 115, 1-13
9.18Citations (PDF)
120Context-dependent compensation among phosphatidylserine-recognition receptors3.431Citations (PDF)
121Multimodal nonlinear optical imaging of unstained retinas in the epi-direction with a sub-40 fs Yb-fiber laser2.813Citations (PDF)
122Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness2.254Citations (PDF)
123Formation and Clearance of All- Trans -Retinol in Rods Investigated in the Living Primate Eye With Two-Photon Ophthalmoscopy
2017, 58, 604
31Citations (PDF)
124Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes
2016, 57, 4272
63Citations (PDF)
125Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye
2016, 57, 632
69Citations (PDF)
126In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones
2016, 57, 647
42Citations (PDF)
127Image registration and averaging of low laser power two-photon fluorescence images of mouse retina2.820Citations (PDF)
128Safety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humans2.828Citations (PDF)
129Mechanistic Studies on the Stereoselectivity of the Serotonin 5‐HT1A Receptor14.430Citations (PDF)
130Mechanistic Studies on the Stereoselectivity of the Serotonin 5‐HT<sub>1A</sub> Receptor
Angewandte Chemie, 2016, 128, 8803-8807
1.42Citations (PDF)
131Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium
Journal of Biological Chemistry, 2016, 291, 26937-26949
2.221Citations (PDF)
132Retinoids and Retinal Diseases4.5102Citations (PDF)
133Conformational Change of Human Checkpoint Kinase 1 (Chk1) Induced by DNA Damage
Journal of Biological Chemistry, 2016, 291, 12951-12959
2.226Citations (PDF)
134A small molecule mitigates hearing loss in a mouse model of Usher syndrome III
Nature Chemical Biology, 2016, 12, 444-451
11.848Citations (PDF)
135Key Residues for Catalytic Function and Metal Coordination in a Carotenoid Cleavage Dioxygenase
Journal of Biological Chemistry, 2016, 291, 19401-19412
2.230Citations (PDF)
136The Molecular Mechanism of P2Y1Receptor Activation
Angewandte Chemie, 2016, 128, 10487-10491
1.43Citations (PDF)
137The Molecular Mechanism of P2Y1Receptor Activation14.454Citations (PDF)
138Transcriptome analysis reveals rod/cone photoreceptor specific signatures across mammalian retinas
Human Molecular Genetics, 2016, , ddw268
2.937Citations (PDF)
139Synergistically acting agonists and antagonists of G protein–coupled receptors prevent photoreceptor cell degeneration5.437Citations (PDF)
140Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family
Biochemistry, 2016, 55, 6545-6557
2.432Citations (PDF)
141Lecithin:Retinol Acyltransferase: A Key Enzyme Involved in the Retinoid (visual) Cycle
Biochemistry, 2016, 55, 3082-3091
2.443Citations (PDF)
142An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device
Analytical Biochemistry, 2016, 499, 63-65
2.436Citations (PDF)
143The Biochemical Basis of Vitamin A3 Production in Arthropod Vision
ACS Chemical Biology, 2016, 11, 1049-1057
3.730Citations (PDF)
144The impact of microRNA gene regulation on the survival and function of mature cell types in the eye
FASEB Journal, 2016, 30, 23-33
0.642Citations (PDF)
145Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders11.829Citations (PDF)
146The Mechanism of Ligand‐Induced Activation or Inhibition of μ‐ and κ‐Opioid Receptors14.448Citations (PDF)
147Retinol dehydrogenase 8 and ATP‐binding cassette transporter 4 modulate dark adaptation of M‐cones in mammalian retina
Journal of Physiology, 2015, 593, 4923-4941
3.416Citations (PDF)
148The Mechanism of Ligand‐Induced Activation or Inhibition of μ‐ and κ‐Opioid Receptors
Angewandte Chemie, 2015, 127, 7670-7673
1.45Citations (PDF)
149Manganese-Enhanced MRI for Preclinical Evaluation of Retinal Degeneration Treatments
2015, 56, 4936
14Citations (PDF)
150A High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation
2015, 56, 2553
17Citations (PDF)
151Utilization of Dioxygen by Carotenoid Cleavage Oxygenases
Journal of Biological Chemistry, 2015, 290, 30212-30223
2.261Citations (PDF)
152Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice
Journal of Biological Chemistry, 2015, 290, 27239-27247
2.225Citations (PDF)
153Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability
FASEB Journal, 2015, 29, 2194-2204
0.650Citations (PDF)
154Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degeneration
Human Molecular Genetics, 2015, 24, 2627-2640
2.923Citations (PDF)
155Isotopic labeling of mammalian G protein-coupled receptors heterologously expressed in Caenorhabditis elegans
Analytical Biochemistry, 2015, 472, 30-36
2.47Citations (PDF)
156Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations
Human Molecular Genetics, 2015, 24, 3220-3237
2.997Citations (PDF)
157Expansion of First-in-Class Drug Candidates That Sequester Toxic All-Trans-Retinal and Prevent Light-Induced Retinal Degeneration
Molecular Pharmacology, 2015, 87, 477-491
2.625Citations (PDF)
158Improvement in vision: a new goal for treatment of hereditary retinal degenerations1.024Citations (PDF)
159Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles
Biomaterials, 2015, 44, 103-110
12.124Citations (PDF)
160Catalytic mechanism of a retinoid isomerase essential for vertebrate vision
Nature Chemical Biology, 2015, 11, 409-415
11.884Citations (PDF)
161Periscope for noninvasive two-photon imaging of murine retina in vivo2.823Citations (PDF)
162Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinas2.82Citations (PDF)
163Self‐Assembly of a Multifunctional Lipid With Core–Shell Dendrimer DNA Nanoparticles Enhanced Efficient Gene Delivery at Low Charge Ratios into RPE Cells
Macromolecular Bioscience, 2015, 15, 1663-1672
4.035Citations (PDF)
164Serum levels of lipid metabolites in age‐related macular degeneration
FASEB Journal, 2015, 29, 4579-4588
0.628Citations (PDF)
165Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium
Journal of Biological Chemistry, 2015, 290, 29035-29044
2.236Citations (PDF)
166Retinylamine Benefits Early Diabetic Retinopathy in Mice
Journal of Biological Chemistry, 2015, 290, 21568-21579
2.253Citations (PDF)
167Disruption of Rhodopsin Dimerization with Synthetic Peptides Targeting an Interaction Interface
Journal of Biological Chemistry, 2015, 290, 25728-25744
2.282Citations (PDF)
168Advances in understanding the molecular basis of the first steps in color vision12.943Citations (PDF)
169Molecular pharmacodynamics of emixustat in protection against retinal degeneration
Journal of Clinical Investigation, 2015, 125, 2781-2794
10.673Citations (PDF)
170R9AP Overexpression Alters Phototransduction Kinetics in iCre75 Mice
2014, 55, 1339
16Citations (PDF)
171Endogenous Fluorophores Enable Two-Photon Imaging of the Primate Eye
2014, 55, 4438
34Citations (PDF)
172Chemistry and Biology of the Initial Steps in Vision: The Friedenwald Lecture
2014, 55, 6651
66Citations (PDF)
173Analysis of Carotenoid Isomerase Activity in a Prototypical Carotenoid Cleavage Enzyme, Apocarotenoid Oxygenase (ACO)
Journal of Biological Chemistry, 2014, 289, 12286-12299
2.229Citations (PDF)
174Human infrared vision is triggered by two-photon chromophore isomerization7.5108Citations (PDF)
175Multifunctional PEG Retinylamine Conjugate Provides Prolonged Protection against Retinal Degeneration in Mice
Biomacromolecules, 2014, 15, 4570-4578
5.111Citations (PDF)
176Structural Insights into Activation of the Retinal L-type Ca2+ Channel (Cav1.4) by Ca2+-binding Protein 4 (CaBP4)
Journal of Biological Chemistry, 2014, 289, 31262-31273
2.215Citations (PDF)
177STRA6 is critical for cellular vitamin A uptake and homeostasis
Human Molecular Genetics, 2014, 23, 5402-5417
2.9124Citations (PDF)
178Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice7.568Citations (PDF)
179Identification and Characterization of Novel Inhibitors of Mammalian Aspartyl Aminopeptidase
Molecular Pharmacology, 2014, 86, 231-242
2.615Citations (PDF)
180The macular degeneration-linked C1QTNF5 (S163) mutation causes higher-order structural rearrangements2.321Citations (PDF)
181Chemistry of the Retinoid (Visual) Cycle
Chemical Reviews, 2014, 114, 194-232
52.5346Citations (PDF)
182Human Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9-cis-Retinal Isomerase Activity15.017Citations (PDF)
183Reliable Determination of Site-Specific In Vivo Protein N-Glycosylation Based on Collision-Induced MS/MS and Chromatographic Retention Time2.642Citations (PDF)
184Inherent Instability of the Retinitis Pigmentosa P23H Mutant Opsin
Journal of Biological Chemistry, 2014, 289, 9288-9303
2.255Citations (PDF)
185DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice
FASEB Journal, 2014, 28, 3780-3791
0.663Citations (PDF)
186Argonaute High-Throughput Sequencing of RNAs Isolated by Cross-Linking Immunoprecipitation Reveals a Snapshot of miRNA Gene Regulation in the Mammalian Retina
Biochemistry, 2014, 53, 5831-5833
2.44Citations (PDF)
187Synthesis and Evaluation of a Nanoglobular Dendrimer 5-Aminosalicylic Acid Conjugate with a Hydrolyzable Schiff Base Spacer for Treating Retinal Degeneration
ACS Nano, 2014, 8, 153-161
15.331Citations (PDF)
188High‐resolution crystal structures of the photoreceptor glyceraldehyde 3‐phosphate dehydrogenase (GAPDH) with three and four‐bound NAD molecules
Protein Science, 2014, 23, 1629-1639
5.921Citations (PDF)
189Activation of G-protein-coupled receptors correlates with the formation of a continuous internal water pathway13.7233Citations (PDF)
190Structural approaches to understanding retinal proteins needed for vision3.915Citations (PDF)
191Time-Resolved Fluorescence Spectroscopy Measures Clustering and Mobility of a G Protein-Coupled Receptor Opsin in Live Cell Membranes15.062Citations (PDF)
192Expression, purification and structural properties of ABC transporter ABCA4 and its individual domains1.218Citations (PDF)
193P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis
Human Molecular Genetics, 2014, 23, 1723-1741
2.9116Citations (PDF)
194LRAT-specific domain facilitates vitamin A metabolism by domain swapping in HRASLS3
Nature Chemical Biology, 2014, 11, 26-32
11.858Citations (PDF)
195Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration
Molecular Neurobiology, 2014, 52, 679-695
3.7149Citations (PDF)
196Serial Block Face‐Scanning Electron Microscopy: A Method to Study Retinal Degenerative Phenotypes3.114Citations (PDF)
197Retinal degeneration in animal models with a defective visual cycle1.618Citations (PDF)
198Structural basis of carotenoid cleavage: From bacteria to mammals2.8142Citations (PDF)
199Retinal Pigmented Epithelial Cells Obtained from Human Induced Pluripotent Stem Cells Possess Functional Visual Cycle Enzymes in Vitro and in Vivo
Journal of Biological Chemistry, 2013, 288, 34484-34493
2.277Citations (PDF)
200Asymmetry of the rhodopsin dimer in complex with transducin
FASEB Journal, 2013, 27, 1572-1584
0.661Citations (PDF)
201Characterization of human β,β-carotene-15,15′-monooxygenase (BCMO1) as a soluble monomeric enzyme2.836Citations (PDF)
202From Atomic Structures to Neuronal Functions of G Protein–Coupled Receptors11.441Citations (PDF)
203The rhodopsin-transducin complex houses two distinct rhodopsin molecules
Journal of Structural Biology, 2013, 182, 164-172
2.342Citations (PDF)
204Molecular Organization and ATP-Induced Conformational Changes of ABCA4, the Photoreceptor-Specific ABC Transporter
Structure, 2013, 21, 854-860
3.854Citations (PDF)
205Cellular Retinaldehyde Binding Protein—Different Binding Modes and Micro-Solvation Patterns for High-Affinity 9-cis- and 11-cis-Retinal Substrates
Journal of Physical Chemistry B, 2013, 117, 10719-10729
2.78Citations (PDF)
2063D imaging and quantitative analysis of small solubilized membrane proteins and their complexes by transmission electron microscopy1.621Citations (PDF)
207In vivo two-photon imaging of the mouse retina2.885Citations (PDF)
208Evolutionarily conserved long intergenic non-coding RNAs in the eye
Human Molecular Genetics, 2013, 22, 2992-3002
2.942Citations (PDF)
209QLT091001, a 9-cis-Retinal Analog, Is Well-Tolerated by Retinas of Mice with Impaired Visual Cycles
2013, 54, 455
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210Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina7.5323Citations (PDF)
211A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4)3.030Citations (PDF)
212Structural and Functional Analysis of the Native Peripherin-ROM1 Complex Isolated from Photoreceptor Cells
Journal of Biological Chemistry, 2013, 288, 36272-36284
2.250Citations (PDF)
213Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal
Journal of Biological Chemistry, 2013, 288, 15326-15341
2.2166Citations (PDF)
214Photoreceptor phagocytosis is mediated by phosphoinositide signaling
FASEB Journal, 2013, 27, 4585-4595
0.642Citations (PDF)
215Two Carotenoid Oxygenases Contribute to Mammalian Provitamin A Metabolism
Journal of Biological Chemistry, 2013, 288, 34081-34096
2.2172Citations (PDF)
216Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization10.632Citations (PDF)
217Systems pharmacology identifies drug targets for Stargardt disease–associated retinal degeneration
Journal of Clinical Investigation, 2013, 123, 5119-5134
10.676Citations (PDF)
218Light-Induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors
PLoS ONE, 2013, 8, e58832
2.312Citations (PDF)
219Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis7.563Citations (PDF)
220Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins
Journal of Biological Chemistry, 2012, 287, 23790-23807
2.277Citations (PDF)
221Lecithin:Retinol Acyltransferase Is Critical for Cellular Uptake of Vitamin A from Serum Retinol-binding Protein
Journal of Biological Chemistry, 2012, 287, 24216-24227
2.290Citations (PDF)
222Thematic Minireview Series on Focus on Vision
Journal of Biological Chemistry, 2012, 287, 1610-1611
2.23Citations (PDF)
223Mechanism of All-trans-retinal Toxicity with Implications for Stargardt Disease and Age-related Macular Degeneration
Journal of Biological Chemistry, 2012, 287, 5059-5069
2.2221Citations (PDF)
224Melanopsin Is Highly Resistant to Light and Chemical Bleaching in Vivo
Journal of Biological Chemistry, 2012, 287, 20888-20897
2.252Citations (PDF)
225Insights into Substrate Specificity and Metal Activation of Mammalian Tetrahedral Aspartyl Aminopeptidase
Journal of Biological Chemistry, 2012, 287, 13356-13370
2.236Citations (PDF)
226Substrate-Induced Changes in the Dynamics of Rhodopsin Kinase (G Protein-Coupled Receptor Kinase 1)
Biochemistry, 2012, 51, 3404-3411
2.414Citations (PDF)
227Light‐sensitive coupling of rhodopsin and melanopsin to G i/o and G q signal transduction in Caenorhabditis elegans
FASEB Journal, 2012, 26, 480-491
0.633Citations (PDF)
228Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration
Journal of Structural Biology, 2012, 180, 439-446
2.336Citations (PDF)
229Post-Translational Modifications of the Serotonin Type 4 Receptor Heterologously Expressed in Mouse Rod Cells
Biochemistry, 2012, 51, 214-224
2.412Citations (PDF)
230Imaging of Protein Crystals with Two-Photon Microscopy
Biochemistry, 2012, 51, 1625-1637
2.428Citations (PDF)
231Heterologous expression of functional G‐protein‐coupled receptors in Caenorhabditis elegans
FASEB Journal, 2012, 26, 492-502
0.617Citations (PDF)
232Key enzymes of the retinoid (visual) cycle in vertebrate retina2.4164Citations (PDF)
233A Microparticle/Hydrogel Combination Drug-Delivery System for Sustained Release of Retinoids
2012, 53, 6314
29Citations (PDF)
234Chemistry and Biology of Vision
Journal of Biological Chemistry, 2012, 287, 1612-1619
2.2271Citations (PDF)
235The physiological impact of microRNA gene regulation in the retina5.560Citations (PDF)
236Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light‐induced damage
Journal of Neurochemistry, 2012, 121, 146-156
3.843Citations (PDF)
237Conformational Dynamics of Activation for the Pentameric Complex of Dimeric G Protein-Coupled Receptor and Heterotrimeric G Protein
Structure, 2012, 20, 826-840
3.867Citations (PDF)
238Inflammatory priming predisposes mice to age-related retinal degeneration
Journal of Clinical Investigation, 2012, 122, 2989-3001
10.659Citations (PDF)
239Posttranslational Modifications of the Photoreceptor-Specific ABC Transporter ABCA4
Biochemistry, 2011, 50, 6855-6866
2.438Citations (PDF)
240Detergents Stabilize the Conformation of Phosphodiesterase 6
Biochemistry, 2011, 50, 9520-9531
2.44Citations (PDF)
241Enzymatic Properties and Regulation of the Native Isozymes of Retinal Membrane Guanylyl Cyclase (RetGC) from Mouse Photoreceptors
Biochemistry, 2011, 50, 5590-5600
2.492Citations (PDF)
242Heterogeneous N-Terminal Acylation of Retinal Proteins Results from the Retina’s Unusual Lipid Metabolism
Biochemistry, 2011, 50, 3764-3776
2.49Citations (PDF)
243Activation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase Domain
Biochemistry, 2011, 50, 1940-1949
2.453Citations (PDF)
244Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy2.894Citations (PDF)
245Rhodopsin–transducin heteropentamer: Three-dimensional structure and biochemical characterization
Journal of Structural Biology, 2011, 176, 387-394
2.357Citations (PDF)
246Role of membrane integrity on G protein-coupled receptors: Rhodopsin stability and function
Progress in Lipid Research, 2011, 50, 267-277
14.369Citations (PDF)
247The Significance of G Protein-Coupled Receptor Crystallography for Drug Discovery
Pharmacological Reviews, 2011, 63, 901-937
15.7214Citations (PDF)
248Serial sectioning for examination of photoreceptor cell architecture by focused ion beam technology2.214Citations (PDF)
249Focus on vision: 3 decades of remarkable contributions to biology and medicine
FASEB Journal, 2011, 25, 439-443
0.63Citations (PDF)
250Vitamin A Deficiency Results in Meiotic Failure and Accumulation of Undifferentiated Spermatogonia in Prepubertal Mouse Testis
Biology of Reproduction, 2011, 84, 336-341
2.568Citations (PDF)
251Toll-like Receptor 3 Is Required for Development of Retinopathy Caused by Impaired All-trans-retinal Clearance in Mice
Journal of Biological Chemistry, 2011, 286, 15543-15555
2.263Citations (PDF)
252Retinyl Ester Storage Particles (Retinosomes) from the Retinal Pigmented Epithelium Resemble Lipid Droplets in Other Tissues
Journal of Biological Chemistry, 2011, 286, 17248-17258
2.283Citations (PDF)
253Probing Mechanisms of Photoreceptor Degeneration in a New Mouse Model of the Common Form of Autosomal Dominant Retinitis Pigmentosa due to P23H Opsin Mutations
Journal of Biological Chemistry, 2011, 286, 10551-10567
2.2293Citations (PDF)
254Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1
Journal of Biological Chemistry, 2011, 286, 5607-5613
2.2137Citations (PDF)
255Dietary 9-cis-β,β-Carotene Fails to Rescue Vision in Mouse Models of Leber Congenital Amaurosis
Molecular Pharmacology, 2011, 80, 943-952
2.637Citations (PDF)
256Role of Bulk Water in Hydrolysis of the Rhodopsin Chromophore
Journal of Biological Chemistry, 2011, 286, 18930-18937
2.260Citations (PDF)
257Sponge Transgenic Mouse Model Reveals Important Roles for the MicroRNA-183 (miR-183)/96/182 Cluster in Postmitotic Photoreceptors of the Retina
Journal of Biological Chemistry, 2011, 286, 31749-31760
2.2116Citations (PDF)
258Defective photoreceptor phagocytosis in a mouse model of enhanced S‐cone syndrome causes progressive retinal degeneration
FASEB Journal, 2011, 25, 3157-3176
0.681Citations (PDF)
259A mitochondrial enzyme degrades carotenoids and protects against oxidative stress
FASEB Journal, 2011, 25, 948-959
0.6292Citations (PDF)
260Primary amines protect against retinal degeneration in mouse models of retinopathies
Nature Chemical Biology, 2011, 8, 170-178
11.8134Citations (PDF)
261Complexes between photoactivated rhodopsin and transducin: progress and questions
Biochemical Journal, 2010, 428, 1-10
3.849Citations (PDF)
262Membrane-binding and enzymatic properties of RPE6512.960Citations (PDF)
263Conformational Changes in Guanylate Cyclase-Activating Protein 1 Induced by Ca2+ and N-Terminal Fatty Acid Acylation
Structure, 2010, 18, 116-126
3.820Citations (PDF)
264The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision6.7115Citations (PDF)
265Alpha-Synuclein Disrupted Dopamine Homeostasis Leads to Dopaminergic Neuron Degeneration in Caenorhabditis elegans
PLoS ONE, 2010, 5, e9312
2.337Citations (PDF)
266Electrostatic Compensation Restores Trafficking of the Autosomal Recessive Retinitis Pigmentosa E150K Opsin Mutant to the Plasma Membrane
Journal of Biological Chemistry, 2010, 285, 29446-29456
2.28Citations (PDF)
267Increased adiposity in the retinol saturase‐knockout mouse
FASEB Journal, 2010, 24, 1261-1270
0.651Citations (PDF)
268β,β-Carotene Decreases Peroxisome Proliferator Receptor γ Activity and Reduces Lipid Storage Capacity of Adipocytes in a β,β-Carotene Oxygenase 1-dependent Manner
Journal of Biological Chemistry, 2010, 285, 27891-27899
2.2137Citations (PDF)
269Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity
Journal of Biological Chemistry, 2010, 285, 9667-9682
2.263Citations (PDF)
270A Functional Kinase Homology Domain Is Essential for the Activity of Photoreceptor Guanylate Cyclase 1
Journal of Biological Chemistry, 2010, 285, 1899-1908
2.224Citations (PDF)
271Palmitoylation stabilizes unliganded rod opsin7.550Citations (PDF)
272GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base
Bioinformatics, 2010, 26, 1804-1805
4.776Citations (PDF)
273An Acyl-covalent Enzyme Intermediate of Lecithin:Retinol Acyltransferase*
Journal of Biological Chemistry, 2010, 285, 29217-29222
2.226Citations (PDF)
274Phagocytosis of Retinal Rod and Cone Photoreceptors
Physiology, 2010, 25, 8-15
5.0374Citations (PDF)
275Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses
Glycobiology, 2010, 20, 1643-1653
2.213Citations (PDF)
276Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice3.027Citations (PDF)
277Conformational Changes in the G Protein-Coupled Receptor Rhodopsin Revealed by Histidine Hydrogen−Deuterium Exchange
Biochemistry, 2010, 49, 9425-9427
2.425Citations (PDF)
278Visualizing Water Molecules in Transmembrane Proteins Using Radiolytic Labeling Methods
Biochemistry, 2010, 49, 827-834
2.445Citations (PDF)
279Structural Characterization of the Rod cGMP Phosphodiesterase 6
Journal of Molecular Biology, 2010, 401, 363-373
4.125Citations (PDF)
280Retinoids for treatment of retinal diseases11.4115Citations (PDF)
281Towards functional measurements of vision in the living macaque retina using two-photon fluorescence imaging
Journal of Vision, 2010, 10, 15-15
0.212Citations (PDF)
282Effects of Long-Term Administration of 9-cis-Retinyl Acetate on Visual Function in Mice
2009, 50, 322
28Citations (PDF)
283Evaluation of 9-cis-Retinyl Acetate Therapy inRpe65−/−Mice
2009, 50, 4368
45Citations (PDF)
284Isolation and functional characterization of a stable complex between photoactivated rhodopsin and the G protein, transducin
FASEB Journal, 2009, 23, 371-381
0.629Citations (PDF)
285Structural waters define a functional channel mediating activation of the GPCR, rhodopsin7.5195Citations (PDF)
286Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate
Human Molecular Genetics, 2009, 18, 2277-2287
2.982Citations (PDF)
287Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors7.5227Citations (PDF)
288Structural Insights into Ca2+-dependent Regulation of Inositol 1,4,5-Trisphosphate Receptors by CaBP1
Journal of Biological Chemistry, 2009, 284, 2472-2481
2.253Citations (PDF)
289ABCA4 disease progression and a proposed strategy for gene therapy
Human Molecular Genetics, 2009, 18, 931-941
2.9181Citations (PDF)
290Evaluation of Potential Therapies for a Mouse Model of Human Age-Related Macular Degeneration Caused by Delayed all-trans-Retinal Clearance
2009, 50, 4917
47Citations (PDF)
291Limited Roles of Rdh8, Rdh12, and Abca4 in all-trans-Retinal Clearance in Mouse Retina
2009, 50, 5435
94Citations (PDF)
292Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice
Journal of Biological Chemistry, 2009, 284, 15173-15183
2.2233Citations (PDF)
293Crystal structure of native RPE65, the retinoid isomerase of the visual cycle7.5154Citations (PDF)
294Activation of Retinoic Acid Receptors by Dihydroretinoids
Molecular Pharmacology, 2009, 76, 1228-1237
2.644Citations (PDF)
295Structure of cone photoreceptors12.9242Citations (PDF)
296Use of thallium to identify monovalent cation binding sites in GroEL0.721Citations (PDF)
297Comparative Analysis of GPCR Crystal Structures†2.740Citations (PDF)
298Modulation of Molecular Interactions and Function by Rhodopsin Palmitylation
Biochemistry, 2009, 48, 4294-4304
2.432Citations (PDF)
299Focus on Molecules: Guanylate cyclase-activating proteins (GCAPs)2.518Citations (PDF)
300Phospholipids Are Needed for the Proper Formation, Stability, and Function of the Photoactivated Rhodopsin−Transducin Complex
Biochemistry, 2009, 48, 5159-5170
2.439Citations (PDF)
301Chemokine receptors and other G protein-coupled receptors3.348Citations (PDF)
302Ca2+‐dependent Regulation of Phototransduction†2.750Citations (PDF)
303A novel GCAP1(N104K) mutation in EF-hand 3 (EF3) linked to autosomal dominant cone dystrophy
Vision Research, 2008, 48, 2425-2432
1.242Citations (PDF)
304Mechanical Properties of Bovine Rhodopsin and Bacteriorhodopsin:  Possible Roles in Folding and Function
Langmuir, 2008, 24, 1330-1337
3.648Citations (PDF)
305RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome
Cell Metabolism, 2008, 7, 258-268
25.2190Citations (PDF)
306Structures of Rhodopsin Kinase in Different Ligand States Reveal Key Elements Involved in G Protein-coupled Receptor Kinase Activation
Journal of Biological Chemistry, 2008, 283, 14053-14062
2.291Citations (PDF)
307Different Properties of the Native and Reconstituted Heterotrimeric G Protein Transducin
Biochemistry, 2008, 47, 12409-12419
2.424Citations (PDF)
308Stereospecificity of Retinol Saturase:  Absolute Configuration, Synthesis, and Biological Evaluation of Dihydroretinoids15.040Citations (PDF)
309Impact of Retinal Disease-Associated RPE65 Mutations on Retinoid Isomerization
Biochemistry, 2008, 47, 9856-9865
2.443Citations (PDF)
310Heterologous Expression and Purification of the Serotonin Type 4 Receptor from Transgenic Mouse Retina
Biochemistry, 2008, 47, 13296-13307
2.412Citations (PDF)
311The Molecular Basis of Retinoid Absorption
Journal of Biological Chemistry, 2008, 283, 13510-13519
2.2116Citations (PDF)
312Trafficking of Membrane-Associated Proteins to Cone Photoreceptor Outer Segments Requires the Chromophore 11- cis -Retinal
Journal of Neuroscience, 2008, 28, 4008-4014
3.7102Citations (PDF)
313Activation of G Protein–Coupled Receptors: Beyond Two-State Models and Tertiary Conformational Changes11.8127Citations (PDF)
314Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance
Journal of Biological Chemistry, 2008, 283, 26684-26693
2.2288Citations (PDF)
315Retinyl Ester Homeostasis in the Adipose Differentiation-related Protein-deficient Retina
Journal of Biological Chemistry, 2008, 283, 25091-25102
2.225Citations (PDF)
316Efficient Coupling of Transducin to Monomeric Rhodopsin in a Phospholipid Bilayer
Journal of Biological Chemistry, 2008, 283, 4387-4394
2.2240Citations (PDF)
317Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina
Journal of Biological Chemistry, 2008, 283, 9543-9554
2.290Citations (PDF)
318Retinyl Ester Formation by Lecithin:Retinol Acyltransferase Is a Key Regulator of Retinoid Homeostasis in Mouse Embryogenesis
Journal of Biological Chemistry, 2008, 283, 5611-5621
2.275Citations (PDF)
319Vertebrate Membrane Proteins: Structure, Function, and Insights from Biophysical Approaches
Pharmacological Reviews, 2008, 60, 43-78
15.796Citations (PDF)
320Diseases Caused by Defects in the Visual Cycle: Retinoids as Potential Therapeutic Agents11.8405Citations (PDF)
321Human cone photoreceptor dependence on RPE65 isomerase7.5153Citations (PDF)
322Redundant and unique roles of retinol dehydrogenases in the mouse retina7.5125Citations (PDF)
323The Function of Guanylate Cyclase 1 and Guanylate Cyclase 2 in Rod and Cone Photoreceptors
Journal of Biological Chemistry, 2007, 282, 8837-8847
2.2160Citations (PDF)
324Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography
Journal of Cell Biology, 2007, 177, 917-925
5.4207Citations (PDF)
325International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the Recognition and Nomenclature of G Protein-Coupled Receptor Heteromultimers
Pharmacological Reviews, 2007, 59, 5-13
15.7285Citations (PDF)
326Stabilizing Effect of Zn2+ in Native Bovine Rhodopsin
Journal of Biological Chemistry, 2007, 282, 11377-11385
2.265Citations (PDF)
327Topology and Membrane Association of Lecithin: Retinol Acyltransferase
Journal of Biological Chemistry, 2007, 282, 2081-2090
2.257Citations (PDF)
328Sequestration of Retinyl Esters Is Essential for Retinoid Signaling in the Zebrafish Embryo
Journal of Biological Chemistry, 2007, 282, 1144-1151
2.238Citations (PDF)
329Visual Rhodopsin Sees the Light: Structure and Mechanism of G Protein Signaling
Journal of Biological Chemistry, 2007, 282, 9297-9301
2.2105Citations (PDF)
330Crystal packing analysis of Rhodopsin crystals
Journal of Structural Biology, 2007, 158, 455-462
2.342Citations (PDF)
331Reprint of “Crystal packing analysis of Rhodopsin crystals” [J. Struct. Biol. 158 (2007) 455–462]☆
Journal of Structural Biology, 2007, 159, 253-260
2.32Citations (PDF)
332Delivery of Retinoid-Based Therapies To Target Tissues
Biochemistry, 2007, 46, 4449-4458
2.484Citations (PDF)
333Heterologous Expression of the Adenosine A1 Receptor in Transgenic Mouse Retina
Biochemistry, 2007, 46, 8350-8359
2.417Citations (PDF)
334Specificity of Zebrafish Retinol Saturase:  Formation of All-trans-13,14-dihydroretinol and All-trans-7,8- dihydroretinol
Biochemistry, 2007, 46, 1811-1820
2.444Citations (PDF)
335Purification, crystallization and structure determination of native GroEL fromEscherichia colilacking bound potassium ions0.725Citations (PDF)
336Evidence for RPE65‐independent vision in the cone‐dominated zebrafish retina3.552Citations (PDF)
337Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
BMC Bioinformatics, 2007, 8, 177
3.042Citations (PDF)
338Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: Biochemical and clinical evaluations
Vision Research, 2007, 47, 2055-2066
1.246Citations (PDF)
339Stabilizing Function for Myristoyl Group Revealed by the Crystal Structure of a Neuronal Calcium Sensor, Guanylate Cyclase-Activating Protein 1
Structure, 2007, 15, 1392-1402
3.8117Citations (PDF)
340G Protein–Coupled Receptor Rhodopsin17.4724Citations (PDF)
341Aberrant Metabolites in Mouse Models of Congenital Blinding Diseases:  Formation and Storage of Retinyl Esters†
Biochemistry, 2006, 45, 4210-4219
2.437Citations (PDF)
342Detecting Molecular Interactions that Stabilize Native Bovine Rhodopsin
Journal of Molecular Biology, 2006, 358, 255-269
4.172Citations (PDF)
343The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP-linked Cone Dystrophies
Journal of Molecular Biology, 2006, 359, 266-275
4.145Citations (PDF)
344Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals
Journal of Structural Biology, 2006, 156, 497-504
2.353Citations (PDF)
345Light-Driven Cone Arrestin Translocation in Cones of Postnatal Guanylate Cyclase-1 Knockout Mouse Retina Treated with AAV-GC1
2006, 47, 3745
69Citations (PDF)
346Lentiviral Expression of Retinal Guanylate Cyclase-1 (RetGC1) Restores Vision in an Avian Model of Childhood Blindness
PLoS Medicine, 2006, 3, e201
8.082Citations (PDF)
347Arrestin Interaction With Rhodopsin: Conceptual Models2.039Citations (PDF)
348Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors6.4265Citations (PDF)
349The Role of the 11-cis-Retinal Ring Methyl Substituents in Visual Pigment Formation
ChemBioChem, 2006, 7, 1815-1825
2.613Citations (PDF)
350Improvement in Rod and Cone Function in Mouse Model ofFundus albipunctatusafter Pharmacologic Treatment with 9-cis-Retinal
2006, 47, 4540
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351Effects of Potent Inhibitors of the Retinoid Cycle on Visual Function and Photoreceptor Protection from Light Damage in Mice
Molecular Pharmacology, 2006, 70, 1220-1229
2.684Citations (PDF)
352Functional and Structural Characterization of Rhodopsin Oligomers
Journal of Biological Chemistry, 2006, 281, 11917-11922
2.2130Citations (PDF)
353Rhodopsin self-associates in asolectin liposomes7.592Citations (PDF)
354Inner retinal photoreception independent of the visual retinoid cycle7.564Citations (PDF)
355Retinol Dehydrogenase (RDH12) Protects Photoreceptors from Light-induced Degeneration in Mice
Journal of Biological Chemistry, 2006, 281, 37697-37704
2.2117Citations (PDF)
356Crystal structure of a photoactivated deprotonated intermediate of rhodopsin7.5441Citations (PDF)
357Autosomal Recessive Retinitis Pigmentosa and E150K Mutation in the Opsin Gene
Journal of Biological Chemistry, 2006, 281, 22289-22298
2.223Citations (PDF)
358Characterizing the Metabolism and Physiological Functions of Dihydroretinoids, Charting a Novel Pathway in the Metabolism of Vitamin A
FASEB Journal, 2006, 20,
0.61Citations (PDF)
359Expression of functional G protein‐coupled receptors in photoreceptors of transgenic Xenopus laevis
FASEB Journal, 2006, 20,
0.60Citations (PDF)
360Crystal structure of human guanylate cyclase activating protein‐3
FASEB Journal, 2006, 20,
0.60Citations (PDF)
361A Critical Role of CaBP4 in the Cone Synapse
2005, 46, 4320
52Citations (PDF)
362Pharmacological and rAAV Gene Therapy Rescue of Visual Functions in a Blind Mouse Model of Leber Congenital Amaurosis
PLoS Medicine, 2005, 2, e333
8.0122Citations (PDF)
363Role of Photoreceptor-specific Retinol Dehydrogenase in the Retinoid Cycle in Vivo
Journal of Biological Chemistry, 2005, 280, 18822-18832
2.2157Citations (PDF)
364Delayed Dark Adaptation in 11-cis-Retinol Dehydrogenase-deficient Mice
Journal of Biological Chemistry, 2005, 280, 8694-8704
2.2104Citations (PDF)
365Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle7.5128Citations (PDF)
366Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness
Molecular Therapy, 2005, 12, 1072-1082
10.2452Citations (PDF)
367Lecithin:Retinol Acyltransferase Is Responsible for Amidation of Retinylamine, a Potent Inhibitor of the Retinoid Cycle
Journal of Biological Chemistry, 2005, 280, 42263-42273
2.260Citations (PDF)
368Structural Analysis of Mg2+ and Ca2+ Binding to CaBP1, a Neuron-specific Regulator of Calcium Channels
Journal of Biological Chemistry, 2005, 280, 37461-37470
2.278Citations (PDF)
369Retinoid Absorption and Storage Is Impaired in Mice Lacking Lecithin:Retinol Acyltransferase (LRAT)
Journal of Biological Chemistry, 2005, 280, 35647-35657
2.2282Citations (PDF)
370Metabolism and Transactivation Activity of 13,14-Dihydroretinoic Acid
Journal of Biological Chemistry, 2005, 280, 27815-27825
2.257Citations (PDF)
371A Novel GCAP1 Missense Mutation (L151F) in a Large Family with Autosomal Dominant Cone-Rod Dystrophy (adCORD)
2005, 46, 1124
64Citations (PDF)
372Partial Agonism in a G Protein-coupled Receptor
Journal of Biological Chemistry, 2005, 280, 34259-34267
2.244Citations (PDF)
373Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success7.5267Citations (PDF)
374Microsomal Glutathione S-Transferase 1 in the Retinal Pigment Epithelium:  Protection against Oxidative Stress and a Potential Role in Aging,
Biochemistry, 2005, 44, 480-489
2.487Citations (PDF)
375Expression of Functional G Protein-Coupled Receptors in Photoreceptors of TransgenicXenopus laevis†
Biochemistry, 2005, 44, 14509-14518
2.431Citations (PDF)
376Corrigendum to “Hippocalcin in the olfactory epithelium: a mediator of second messenger signaling” [Biochem. Biophys. Res. Commun. 322 (2004) 1131–1139]2.10Citations (PDF)
377Related enzymes solve evolutionarily recurrent problems in the metabolism of carotenoids
Trends in Plant Science, 2005, 10, 178-186
11.6148Citations (PDF)
378A Novel Mutation (I143NT) in Guanylate Cyclase-Activating Protein 1 (GCAP1) Associated with Autosomal Dominant Cone Degeneration
2004, 45, 3863
139Citations (PDF)
379A Naturally Occurring Mutation of the Opsin Gene (T4R) in Dogs Affects Glycosylation and Stability of the G Protein-coupled Receptor
Journal of Biological Chemistry, 2004, 279, 53828-53839
2.268Citations (PDF)
380Impairment of the Transient Pupillary Light Reflex in Rpe65−/− Mice and Humans with Leber Congenital Amaurosis
2004, 45, 1259
97Citations (PDF)
381Retinosomes
Journal of Cell Biology, 2004, 166, 447-453
5.4101Citations (PDF)
382Lecithin-retinol Acyltransferase Is Essential for Accumulation of All-trans-Retinyl Esters in the Eye and in the Liver
Journal of Biological Chemistry, 2004, 279, 10422-10432
2.2353Citations (PDF)
383Identification of All-trans-Retinol:All-trans-13,14-dihydroretinol Saturase
Journal of Biological Chemistry, 2004, 279, 50230-50242
2.298Citations (PDF)
384Ca2+Binding to EF Hands 1 and 3 Is Essential for the Interaction of Apoptosis-Linked Gene-2 with Alix/AIP1 in Ocular Melanoma†
Biochemistry, 2004, 43, 11175-11186
2.434Citations (PDF)
385Functional Characterization of Rhodopsin Monomers and Dimers in Detergents
Journal of Biological Chemistry, 2004, 279, 54663-54675
2.2120Citations (PDF)
386Rhodopsin Signaling and Organization in Heterozygote Rhodopsin Knockout Mice
Journal of Biological Chemistry, 2004, 279, 48189-48196
2.2149Citations (PDF)
387Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye
Journal of Cell Biology, 2004, 164, 373-383
5.4205Citations (PDF)
388Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function
Nature Neuroscience, 2004, 7, 1079-1087
17.1294Citations (PDF)
389Diversity of Guanylate Cyclase-Activating Proteins (GCAPs) in Teleost Fish: Characterization of Three Novel GCAPs (GCAP4, GCAP5, GCAP7) from Zebrafish (Danio rerio) and Prediction of Eight GCAPs (GCAP1-8) in Pufferfish (Fugu rubripes)1.7101Citations (PDF)
390Oligomerization of G Protein-Coupled Receptors:  Past, Present, and Future†
Biochemistry, 2004, 43, 15643-15656
2.4216Citations (PDF)
391A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface2.3163Citations (PDF)
392Guanylate cyclase-activating proteins: structure, function, and diversity2.1107Citations (PDF)
393Hippocalcin in the olfactory epithelium: a mediator of second messenger signaling2.116Citations (PDF)
394The supramolecular structure of the GPCR rhodopsin in solution and native disc membranes
Molecular Membrane Biology, 2004, 21, 435-446
2.977Citations (PDF)
395The G protein-coupled receptor rhodopsin in the native membrane
FEBS Letters, 2004, 564, 281-288
2.7200Citations (PDF)
396Phototransduction: crystal clear6.7167Citations (PDF)
397Rhodopsin phosphorylation: 30 years later12.9146Citations (PDF)
398Evaluation of the role of the retinal G protein‐coupled receptor (RGR) in the vertebrate retina in vivo
Journal of Neurochemistry, 2003, 85, 944-956
3.884Citations (PDF)
399Rhodopsin dimers in native disc membranes
Nature, 2003, 421, 127-128
37.9753Citations (PDF)
400Is rhodopsin dimeric in native retinal rods?
Nature, 2003, 426, 31-31
37.914Citations (PDF)
401G Protein-Coupled Receptor Rhodopsin: A Prospectus
Annual Review of Physiology, 2003, 65, 851-879
17.0255Citations (PDF)
402Sequence Analyses of G-Protein-Coupled Receptors:  Similarities to Rhodopsin†
Biochemistry, 2003, 42, 2759-2767
2.4348Citations (PDF)
403Evolutionary analysis of rhodopsin and cone pigments: connecting the three-dimensional structure with spectral tuning and signal transfer
FEBS Letters, 2003, 555, 151-159
2.717Citations (PDF)
404Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization
Vision Research, 2003, 43, 2959-2981
1.262Citations (PDF)
405Novel targeting strategy for generating mouse models with defects in the retinoid cycle
Vision Research, 2003, 43, 3075-3079
1.26Citations (PDF)
406Signaling States of Rhodopsin
Journal of Biological Chemistry, 2003, 278, 3162-3169
2.2105Citations (PDF)
407Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation7.5363Citations (PDF)
408Identification of Protein Kinase C Isozymes Responsible for the Phosphorylation of Photoreceptor-specific RGS9-1 at Ser475
Journal of Biological Chemistry, 2003, 278, 8316-8325
2.227Citations (PDF)
409Ligand Channeling within a G-protein-coupled Receptor
Journal of Biological Chemistry, 2003, 278, 24896-24903
2.2107Citations (PDF)
410Pharmacological Chaperone-mediated in Vivo Folding and Stabilization of the P23H-opsin Mutant Associated with Autosomal Dominant Retinitis Pigmentosa
Journal of Biological Chemistry, 2003, 278, 14442-14450
2.2195Citations (PDF)
411Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes
Journal of Biological Chemistry, 2003, 278, 21655-21662
2.2543Citations (PDF)
412The Crystallographic Model of Rhodopsin and Its Use in Studies of Other G Protein–Coupled Receptors17.4117Citations (PDF)
413Recovery of Visual Functions in a Mouse Model of Leber Congenital Amaurosis
Journal of Biological Chemistry, 2002, 277, 19173-19182
2.2144Citations (PDF)
414Biochemical and Physiological Properties of Rhodopsin Regenerated with 11-cis-6-Ring- and 7-Ring-retinals
Journal of Biological Chemistry, 2002, 277, 42315-42324
2.241Citations (PDF)
415Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca2+ release channels7.5184Citations (PDF)
416Dual-substrate Specificity Short Chain Retinol Dehydrogenases from the Vertebrate Retina
Journal of Biological Chemistry, 2002, 277, 45537-45546
2.2207Citations (PDF)
417Soluble Fusion Proteins between Single Transmembrane Photoreceptor Guanylyl Cyclases and Their Activators†
Biochemistry, 2002, 41, 251-257
2.412Citations (PDF)
418Crystal structure of rhodopsin: a template for cone visual pigments and other G protein-coupled receptors2.2104Citations (PDF)
419Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man3.597Citations (PDF)
420Differential modulation of Cav2.1 channels by calmodulin and Ca2+-binding protein 1
Nature Neuroscience, 2002, 5, 210-217
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421Cloning and Characterization of a Human β,β-Carotene-15, 15′-Dioxygenase That Is Highly Expressed in the Retinal Pigment Epithelium
Genomics, 2001, 72, 193-202
2.8157Citations (PDF)
422Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)†,‡
Biochemistry, 2001, 40, 7761-7772
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423Isomerization of 11-cis- Retinoids to All-trans-retinoids in Vitro and in Vivo
Journal of Biological Chemistry, 2001, 276, 48483-48493
2.255Citations (PDF)
424Activation of rhodopsin: new insights from structural and biochemical studies6.7420Citations (PDF)
425Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina12.9350Citations (PDF)
426Crystal structure of rhodopsin: implications for vision and beyond6.4124Citations (PDF)
427Characterization of a Dehydrogenase Activity Responsible for Oxidation of 11-cis-Retinol in the Retinal Pigment Epithelium of Mice with a Disrupted RDH5 Gene
Journal of Biological Chemistry, 2001, 276, 32456-32465
2.266Citations (PDF)
428Identification of Functional Regions of Guanylate Cyclase-Activating Protein 1 (GCAP1) Using GCAP1/GCIP Chimeras2.125Citations (PDF)
429Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors7.5246Citations (PDF)
430Calcium-sensitive Regions of GCAP1 as Observed by Chemical Modifications, Fluorescence, and EPR Spectroscopies
Journal of Biological Chemistry, 2001, 276, 43361-43373
2.239Citations (PDF)
431Mechanism of Rhodopsin Activation as Examined with Ring-constrained Retinal Analogs and the Crystal Structure of the Ground State Protein
Journal of Biological Chemistry, 2001, 276, 26148-26153
2.239Citations (PDF)
432Phosphorylation of RGS9-1 by an Endogenous Protein Kinase in Rod Outer Segments
Journal of Biological Chemistry, 2001, 276, 22287-22295
2.242Citations (PDF)
433Ca2+-binding proteins in the retina: Structure, function, and the etiology of human visual diseases
BioEssays, 2000, 22, 337-350
2.1151Citations (PDF)
434Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness7.5300Citations (PDF)
435Disruption of the 11- cis -Retinol Dehydrogenase Gene Leads to Accumulation of cis -Retinols and cis -Retinyl Esters
Molecular and Cellular Biology, 2000, 20, 4275-4287
2.5129Citations (PDF)
436Stereoisomeric Specificity of the Retinoid Cycle in the Vertebrate Retina
Journal of Biological Chemistry, 2000, 275, 28128-28138
2.251Citations (PDF)
437Five Members of a Novel Ca2+-binding Protein (CABP) Subfamily with Similarity to Calmodulin
Journal of Biological Chemistry, 2000, 275, 1247-1260
2.2246Citations (PDF)
438Ca2+-binding proteins in the retina: from discovery to etiology of human disease11The nucleotide sequences reported in this manuscript have been submitted to the GenBank™/EMBL databank with the following accession numbers: short form of human CaBP1, AF169148; long form of human CaBP1, AF169149; short form of bovine CaBP1, AF169150; long form of bovine CaBP1, AF169151; short form of mouse CaBP1, AF169153; long form of mouse CaBP1, AF1691152; human CaBP2, AF169154; bovine CaBP2, AF169155; short form of mouse 3.639Citations (PDF)
439Isomerization of all-trans-Retinol to cis-Retinols in Bovine Retinal Pigment Epithelial Cells:  Dependence on the Specificity of Retinoid-Binding Proteins
Biochemistry, 2000, 39, 11370-11380
2.496Citations (PDF)
440Light-Induced Conformational Changes of Rhodopsin Probed by Fluorescent Alexa594 Immobilized on the Cytoplasmic Surface
Biochemistry, 2000, 39, 15225-15233
2.442Citations (PDF)
441Three-dimensional Structure of Guanylyl Cyclase Activating Protein-2, a Calcium-sensitive Modulator of Photoreceptor Guanylyl Cyclases
Journal of Biological Chemistry, 1999, 274, 19329-19337
2.2145Citations (PDF)
442Preferential Release of 11-cis-retinol from Retinal Pigment Epithelial Cells in the Presence of Cellular Retinaldehyde-binding Protein
Journal of Biological Chemistry, 1999, 274, 8577-8585
2.2129Citations (PDF)
443β-Arrestin-dependent Desensitization of Luteinizing Hormone/Choriogonadotropin Receptor Is Prevented by a Synthetic Peptide Corresponding to the Third Intracellular Loop of the Receptor
Journal of Biological Chemistry, 1999, 274, 12984-12989
2.247Citations (PDF)
444Molecular Characterization of a Third Member of the Guanylyl Cyclase-activating Protein Subfamily
Journal of Biological Chemistry, 1999, 274, 6526-6535
2.2136Citations (PDF)
445Conformational Changes in Guanylyl Cyclase-activating Protein 1 (GCAP1) and Its Tryptophan Mutants as a Function of Calcium Concentration
Journal of Biological Chemistry, 1999, 274, 19829-19837
2.248Citations (PDF)
446A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes7.545Citations (PDF)
447Structure, alternative splicing, and expression of the human RGS9 gene
Gene, 1999, 240, 23-34
2.368Citations (PDF)
448A novel form of rhodopsin kinase from chicken retina and pineal gland 1
FEBS Letters, 1999, 454, 115-121
2.730Citations (PDF)
449Isomerization ofall-trans-9- and 13-Desmethylretinol by Retinal Pigment Epithelial Cells†
Biochemistry, 1999, 38, 13542-13550
2.417Citations (PDF)
450Kinetics of Visual Pigment Regeneration in Excised Mouse Eyes and in Mice with a Targeted Disruption of the Gene Encoding Interphotoreceptor Retinoid-Binding Protein or Arrestin†
Biochemistry, 1999, 38, 12012-12019
2.4151Citations (PDF)
451Light Inhibition of Bovine Retinal Rod Guanylyl Cyclase Mediated by βγ-Transducin
Biochemistry, 1999, 38, 2611-2616
2.48Citations (PDF)
452Identification of a Guanylyl Cyclase-Activating Protein-Binding Site within the Catalytic Domain of Retinal Guanylyl Cyclase1
Biochemistry, 1999, 38, 1387-1393
2.464Citations (PDF)
453Identification of a Single Phosphorylation Site Within Octopus Rhodopsin2.710Citations (PDF)
454Guanylate-cyclase-inhibitory protein is a frog retinal Ca2+-binding protein related to mammalian guanylate-cyclase-activating proteins
FEBS Journal, 1998, 252, 591-599
0.248Citations (PDF)
455GCAP1(Y99C) Mutant Is Constitutively Active in Autosomal Dominant Cone Dystrophy
Molecular Cell, 1998, 2, 129-133
13.3153Citations (PDF)
456Reduction of all-trans-retinal limits regeneration of visual pigment in mice
Vision Research, 1998, 38, 1325-1333
1.2134Citations (PDF)
457Changes in Biological Activity and Folding of Guanylate Cyclase-Activating Protein 1 as a Function of Calcium†
Biochemistry, 1998, 37, 248-257
2.488Citations (PDF)
458Molecular Forms of Human Rhodopsin Kinase (GRK1)
Journal of Biological Chemistry, 1998, 273, 5124-5131
2.278Citations (PDF)
459Molecular Characterization of a Novel Short-chain Dehydrogenase/Reductase That Reduces All-trans-retinal
Journal of Biological Chemistry, 1998, 273, 21790-21799
2.2170Citations (PDF)
460Phosphorylation of photolyzed rhodopsin is calcium-insensitive in retina permeabilized by  -toxin7.544Citations (PDF)
461Calcium-Sensitive Particulate Guanylyl Cyclase as a Modulator of cAMP in Olfactory Receptor Neurons
Journal of Neuroscience, 1998, 18, 3195-3205
3.763Citations (PDF)
462High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods7.5165Citations (PDF)
463Null mutation in the rhodopsin kinase gene slows recovery kinetics of rod and cone phototransduction in man7.5179Citations (PDF)
464A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype7.5127Citations (PDF)
465Functional Differences in the Interaction of Arrestin and Its Splice Variant, p44, with Rhodopsin
Biochemistry, 1997, 36, 9253-9260
2.4101Citations (PDF)
466Functional Reconstitution of Photoreceptor Guanylate Cyclase with Native and Mutant Forms of Guanylate Cyclase-Activating Protein 1
Biochemistry, 1997, 36, 4295-4302
2.483Citations (PDF)
467The Human GCAP1 and GCAP2 Genes Are Arranged in a Tail-to-Tail Array on the Short Arm of Chromosome 6 (p21.1)
Genomics, 1997, 39, 312-322
2.836Citations (PDF)
468Activation and inactivation steps in the visual transduction pathway4.775Citations (PDF)
469Localization of guanylate cyclase-activating protein 2 in mammalian retinas7.577Citations (PDF)
470GTP-Binding-Protein-Coupled Receptor Kinases Two Mechanistic Models
FEBS Journal, 1997, 248, 261-269
0.2107Citations (PDF)
471Calcium binding to recoverin: implications for secondary structure and membrane association
BBA - Proteins and Proteomics, 1997, 1342, 164-174
2.524Citations (PDF)
472Opsin/all-trans-Retinal Complex Activates Transducin by Different Mechanisms Than Photolyzed Rhodopsin†
Biochemistry, 1996, 35, 2901-2908
2.4144Citations (PDF)
473Calcium Modulation of Bovine Photoreceptor Guanylate Cyclase
Biochemistry, 1996, 35, 8478-8482
2.4125Citations (PDF)
474Expression of GCAP 1 and GCAP2 in the retinal degeneration (rd) mutant chicken retina
FEBS Letters, 1996, 385, 47-52
2.727Citations (PDF)
475Splice Variants of Arrestins
Experimental Eye Research, 1996, 63, 599-602
2.516Citations (PDF)
476Turned on by Ca2+! The physiology and pathology of Ca2+-binding proteins in the retina
Trends in Neurosciences, 1996, 19, 547-554
9.8291Citations (PDF)
477Responses of the phototransduction cascade to dim light.7.538Citations (PDF)
478Structural and Enzymatic Aspects of Rhodopsin Phosphorylation
Journal of Biological Chemistry, 1996, 271, 5215-5224
2.2118Citations (PDF)
479Mechanisms of Opsin Activation
Journal of Biological Chemistry, 1996, 271, 20621-20630
2.2107Citations (PDF)
480Mechanism of rhodopsin phosphorylation
Biophysical Chemistry, 1995, 56, 183-188
2.132Citations (PDF)
481Localization of three genes expressed in retina on mouse Chromosome 11
Mammalian Genome, 1995, 6, 142-144
2.310Citations (PDF)
482Rhodopsin Phosphorylation and Dephosphorylation in Vivo
Journal of Biological Chemistry, 1995, 270, 14259-14262
2.2165Citations (PDF)
483Guanylyl Cyclase Activating Protein
Journal of Biological Chemistry, 1995, 270, 22029-22036
2.2202Citations (PDF)
484Rhodopsin Kinase Autophosphorylation
Journal of Biological Chemistry, 1995, 270, 15294-15298
2.255Citations (PDF)
485Separation of phospho- and non-phosphopeptides using reverse phase column chromatography
FEBS Letters, 1995, 368, 452-454
2.729Citations (PDF)
486Alligator rhodopsin : Sequence and biochemical properties
Experimental Eye Research, 1995, 61, 569-578
2.511Citations (PDF)
487Characterization of a truncated form of arrestin isolated from bovine rod outer segments
Protein Science, 1994, 3, 314-324
5.973Citations (PDF)
488Structure and functions of arrestins
Protein Science, 1994, 3, 1355-1361
5.984Citations (PDF)
489Topographic study of arrestin using differential chemical modifications and hydrogen/deuterium exchange
Protein Science, 1994, 3, 2428-2434
5.989Citations (PDF)
490Inositolhexakisphosphate (InsP6): An antagonist of fibroblast growth factor receptor binding and activity1.531Citations (PDF)
491Control of Rhodopsin Multiple Phosphorylation
Biochemistry, 1994, 33, 1023-1028
2.491Citations (PDF)
492Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-activating protein
Neuron, 1994, 13, 395-404
11.0456Citations (PDF)
493Nucleotide Inhibitors and Activators of Retinal Guanylyl Cyclase
Biochemistry, 1994, 33, 3217-3222
2.462Citations (PDF)
494Rod Outer Segment Retinol Dehydrogenase: Substrate Specificity and Role in Phototransduction
Biochemistry, 1994, 33, 13741-13750
2.4183Citations (PDF)
495Opsins with mutations at the site of chromophore attachment constitutively activate transducin but are not phosphorylated by rhodopsin kinase.7.544Citations (PDF)
496Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods.7.5313Citations (PDF)
497Heterogeneous N-acylation is a tissue- and species-specific posttranslational modification.
Journal of Biological Chemistry, 1994, 269, 21067-21071
2.2105Citations (PDF)
498Purification and primary structure of Capl, an S-100-related calcium-binding protein isolated from bovine retina.
Journal of Biological Chemistry, 1994, 269, 6233-6240
2.221Citations (PDF)
499A splice variant of arrestin. Molecular cloning and localization in bovine retina.
Journal of Biological Chemistry, 1994, 269, 15407-15410
2.294Citations (PDF)
500Molecular characterization of human and mouse photoreceptor guanylate cyclase-activating protein (GCAP) and chromosomal localization of the human gene.
Journal of Biological Chemistry, 1994, 269, 31080-31089
2.265Citations (PDF)
501Assays of Retinoid Dehydrogenases by Phase Partition
Analytical Biochemistry, 1993, 213, 128-132
2.420Citations (PDF)
502The Kinetics of Multiphosphorylation of Rhodopsin2.826Citations (PDF)
503Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation
Biochemistry, 1993, 32, 14082-14088
2.4192Citations (PDF)
504Sequential phosphorylation of rhodopsin at multiple sites
Biochemistry, 1993, 32, 5718-5724
2.4263Citations (PDF)
505The effect of recoverin-like calcium-Binding proteins on the photoresponse of retinal rods
Neuron, 1993, 10, 523-531
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506Beta-arrestin and arrestin are recognized by autoantibodies in sera from multiple sclerosis patients.7.549Citations (PDF)
507Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin.
Journal of Biological Chemistry, 1993, 268, 6004-6013
2.2132Citations (PDF)
508The influence of arrestin (48K protein) and rhodopsin kinase on visual transduction
Neuron, 1992, 8, 117-126
11.0211Citations (PDF)
509Structural properties of arrestin studied by chemical modification and circular dichroism
Biochemistry, 1992, 31, 3902-3906
2.428Citations (PDF)
510Identification of the autophosphorylation sites in rhodopsin kinase.
Journal of Biological Chemistry, 1992, 267, 18991-18998
2.268Citations (PDF)
511The role of arrestin and retinoids in the regeneration pathway of rhodopsin.
Journal of Biological Chemistry, 1992, 267, 15701-15706
2.2194Citations (PDF)
512G-protein-coupled receptor kinases6.7230Citations (PDF)
513Properties of solubilized and reconstituted A1 adenosine receptors from bovine brain
Pharmacological Research, 1991, 24, 15-23
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514Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase
Biochemistry, 1991, 30, 5118-5125
2.4244Citations (PDF)
515Binding of inositol phosphates to arrestin
FEBS Letters, 1991, 295, 195-199
2.764Citations (PDF)
516Elevated level of protein phosphatase 2A activity in retinas of rd mice
Experimental Eye Research, 1991, 53, 101-105
2.519Citations (PDF)
517Anti-rhodopsin monoclonal antibodies of defined specificity: Characterization and application
Vision Research, 1991, 31, 17-31
1.2228Citations (PDF)
518The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.7.5194Citations (PDF)
519Regulation of rhodopsin kinase by autophosphorylation.7.5180Citations (PDF)
520Phosphorylated rhodopsin and heparin induce similar conformational changes in arrestin.
Journal of Biological Chemistry, 1991, 266, 18649-18654
2.2120Citations (PDF)
521Role of the carboxyl-terminal region of arrestin in binding to phosphorylated rhodopsin
Journal of Biological Chemistry, 1991, 266, 15334-15339
2.291Citations (PDF)
522Mechanism of rhodopsin kinase activation
Journal of Biological Chemistry, 1991, 266, 12949-12955
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523Studies of ligand binding to arrestin
Journal of Biological Chemistry, 1991, 266, 4201-4206
2.229Citations (PDF)
524Phosphorylation of iodopsin, chicken red-sensitive cone visual pigment
Biochemistry, 1990, 29, 10102-10106
2.435Citations (PDF)
525Nucleoside inhibitors of rhodopsin kinase
Biochemistry, 1990, 29, 6276-6282
2.448Citations (PDF)
526Molecular, enzymatic and functional properties of rhodopsin kinase from rat pineal gland
Vision Research, 1990, 30, 1129-1137
1.227Citations (PDF)
527Synthetic phosphopeptides are substrates for casein kinase II
FEBS Letters, 1990, 261, 117-120
2.771Citations (PDF)
528X-ray crystal structure of sangivamycin, a potent inhibitor of protein kinases
FEBS Letters, 1990, 266, 102-104
2.78Citations (PDF)
529Substrate recognition determinants for rhodopsin kinase: studies with synthetic peptides, polyanions, and polycations
Biochemistry, 1989, 28, 8764-8770
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530The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin
Biochemistry, 1989, 28, 415-419
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531Synthesis of phosphopeptides containing O‐phosphoserine or O‐phosphothreonine0.137Citations (PDF)
532Regulation of Rhodopsin Dephosphorylation by Arrestin
Journal of Biological Chemistry, 1989, 264, 15770-15773
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533Rhodopsin kinase: substrate specificity and factors that influence activity
Biochemistry, 1988, 27, 2306-2313
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534Purification and characterization of rhodopsin kinase.
Journal of Biological Chemistry, 1988, 263, 14067-14073
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535Photoaffinity labeling of rabbit muscle fructose-1,6-bisphosphate aldolase with 8-azido-1,N6-ethenoadenosine 5'-triphosphate
Biochemistry, 1987, 26, 3466-3471
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536Purification and properties of porcine brain aldolase C0.95Citations (PDF)
537Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance15.510Citations (PDF)
538Dominant and recessive mutations in rhodopsin activate different cell death pathways2.944Citations (PDF)
539Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease
ELife, 0, 9,
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540Determinants shaping the nanoscale architecture of the mouse rod outer segment
ELife, 0, 10,
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541Scalable purification enables high-quality virus-like particles for therapeutic translation2.21Citations (PDF)
542Structural analysis of rhodopsin states in megabody complexes7.50Citations (PDF)
543Lipid-nanoparticle-mediated base editing of the trabecular meshwork rescues glaucoma in vivo
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544Multiphoton Excitation in Retinal Imaging and Functional Measurements4.50Citations (PDF)