| 1 | Cancer Prevalence across Vertebrates | 26.4 | 5 | Citations (PDF) |
| 2 | Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States | 26.4 | 0 | Citations (PDF) |
| 3 | Phenotypic noise and plasticity in cancer evolution | 15.3 | 6 | Citations (PDF) |
| 4 | FUME-TCRseq Enables Sensitive and Accurate Sequencing of the T-cell Receptor from Limited Input of Degraded RNA | 0.6 | 2 | Citations (PDF) |
| 5 | Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer | 16.3 | 1 | Citations (PDF) |
| 6 | The genomic landscape of 2,023 colorectal cancers | 40.1 | 14 | Citations (PDF) |
| 7 | Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors | 16.3 | 25 | Citations (PDF) |
| 8 | First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer | 3.3 | 1 | Citations (PDF) |
| 9 | Bridging clinic and wildlife care with AI-powered pan-species computational pathology | 14.1 | 2 | Citations (PDF) |
| 10 | Virtual alignment of pathology image series for multi-gigapixel whole slide images | 14.1 | 25 | Citations (PDF) |
| 11 | Contribution of pks+ E. coli mutations to colorectal carcinogenesis | 14.1 | 23 | Citations (PDF) |
| 12 | Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool | 14.8 | 14 | Citations (PDF) |
| 13 | Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues | 18.1 | 26 | Citations (PDF) |
| 14 | Immunosuppressive niche engineering at the onset of human colorectal cancer | 14.1 | 21 | Citations (PDF) |
| 15 | Lineage tracing in human tissues | 5.2 | 8 | Citations (PDF) |
| 16 | The mutational signatures of formalin fixation on the human genome | 14.1 | 34 | Citations (PDF) |
| 17 | Phenotypic plasticity and genetic control in colorectal cancer evolution | 40.1 | 74 | Citations (PDF) |
| 18 | The co-evolution of the genome and epigenome in colorectal cancer | 40.1 | 54 | Citations (PDF) |
| 19 | The role of single-cell sequencing in studying tumour evolution | 4.5 | 1 | Citations (PDF) |
| 20 | Predicting Colorectal Cancer Occurrence in IBD | 4.0 | 28 | Citations (PDF) |
| 21 | Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns | 16.3 | 38 | Citations (PDF) |
| 22 | LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations | 3.8 | 6 | Citations (PDF) |
| 23 | Evolutionary dynamics in Barrett oesophagus: implications for surveillance, risk stratification and therapy | 14.7 | 7 | Citations (PDF) |
| 24 | Concurrent in situ analysis of point mutations and immune infiltrate in FFPE cancers | 1.0 | 0 | Citations (PDF) |
| 25 | Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology | 14.1 | 38 | Citations (PDF) |
| 26 | Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype | 13.1 | 40 | Citations (PDF) |
| 27 | Subclonal reconstruction of tumors by using machine learning and population genetics | 16.3 | 63 | Citations (PDF) |
| 28 | Evolutionary dynamics of neoantigens in growing tumors | 16.3 | 61 | Citations (PDF) |
| 29 | Cancer associated fibroblast FAK regulates malignant cell metabolism | 14.1 | 110 | Citations (PDF) |
| 30 | Navigating the path to distant metastasis | 16.3 | 7 | Citations (PDF) |
| 31 | Measuring single cell divisions in human tissues from multi-region sequencing data | 14.1 | 39 | Citations (PDF) |
| 32 | Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma | 4.3 | 5 | Citations (PDF) |
| 33 | In Situ Point Mutation Detection in FFPE Colorectal Cancers Using the BaseScope Assay | 0.0 | 1 | Citations (PDF) |
| 34 | Evolutionary history of human colitis-associated colorectal cancer | 14.8 | 111 | Citations (PDF) |
| 35 | Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data | 3.3 | 45 | Citations (PDF) |
| 36 | Measuring Clonal Evolution in Cancer with Genomics | 7.4 | 49 | Citations (PDF) |
| 37 | Resolving genetic heterogeneity in cancer | 19.1 | 423 | Citations (PDF) |
| 38 | Crypt fusion as a homeostatic mechanism in the human colon | 14.8 | 27 | Citations (PDF) |
| 39 | Multiregion human bladder cancer sequencing reveals tumour evolution, bladder cancer phenotypes and implications for targeted therapy | 5.2 | 31 | Citations (PDF) |
| 40 | Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study | 14.8 | 136 | Citations (PDF) |
| 41 | Author response: Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios 2019, , | | 0 | Citations (PDF) |
| 42 | Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels | 14.1 | 40 | Citations (PDF) |
| 43 | Somatic <i>POLE</i> exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response | 5.2 | 70 | Citations (PDF) |
| 44 | Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma | 8.1 | 94 | Citations (PDF) |
| 45 | Insights Into the Pathophysiology of Esophageal Adenocarcinoma | 1.0 | 67 | Citations (PDF) |
| 46 | Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’ | 16.3 | 4 | Citations (PDF) |
| 47 | From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology | 5.0 | 27 | Citations (PDF) |
| 48 | Reply to ‘Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution’ | 16.3 | 9 | Citations (PDF) |
| 49 | Reply to ‘Neutral tumor evolution?’ | 16.3 | 17 | Citations (PDF) |
| 50 | The evolutionary landscape of colorectal tumorigenesis | 7.6 | 86 | Citations (PDF) |
| 51 | Detecting repeated cancer evolution from multi-region tumor sequencing data | 14.5 | 108 | Citations (PDF) |
| 52 | Quantification of subclonal selection in cancer from bulk sequencing data | 16.3 | 158 | Citations (PDF) |
| 53 | The effects of mutational processes and selection on driver mutations across cancer types | 14.1 | 76 | Citations (PDF) |
| 54 | Reply: Is the evolution of tumors Darwinian or non-Darwinian? | 10.0 | 1 | Citations (PDF) |
| 55 | Catch my drift? Making sense of genomic intra-tumour heterogeneity | 7.1 | 24 | Citations (PDF) |
| 56 | Clonal evolution of colorectal cancer in IBD | 14.7 | 125 | Citations (PDF) |
| 57 | Evolution of Premalignant Disease | 6.7 | 23 | Citations (PDF) |
| 58 | Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures | 16.3 | 5 | Citations (PDF) |
| 59 | Classifying the evolutionary and ecological features of neoplasms | 24.2 | 306 | Citations (PDF) |
| 60 | Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution | 14.1 | 47 | Citations (PDF) |
| 61 | Quantification of within-sample genetic heterogeneity from SNP-array data | 3.7 | 6 | Citations (PDF) |
| 62 | Between-region genetic divergence reflects the mode and tempo of tumor evolution | 16.3 | 102 | Citations (PDF) |
| 63 | PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression | 5.0 | 14 | Citations (PDF) |
| 64 | Measuring cancer evolution from the genome | 5.2 | 104 | Citations (PDF) |
| 65 | An evolutionary perspective on field cancerization | 24.2 | 322 | Citations (PDF) |
| 66 | New paradigms in clonal evolution: punctuated equilibrium in cancer | 5.2 | 70 | Citations (PDF) |
| 67 | A Computational Modeling Approach for Deriving Biomarkers to Predict Cancer Risk in Premalignant Disease | 1.1 | 17 | Citations (PDF) |
| 68 | Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus | 14.1 | 71 | Citations (PDF) |
| 69 | Functional versus non-functional intratumor heterogeneity in cancer | 2.0 | 4 | Citations (PDF) |
| 70 | Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy | 14.1 | 74 | Citations (PDF) |
| 71 | Identification of neutral tumor evolution across cancer types | 16.3 | 433 | Citations (PDF) |
| 72 | Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus | 14.8 | 37 | Citations (PDF) |
| 73 | Quantifying human intestinal stem cell and crypt dynamics: the implications for cancer screening and prevention | 2.4 | 3 | Citations (PDF) |
| 74 | Derivation of genetic biomarkers for cancer risk stratification in Barrett’s oesophagus: a prospective cohort study | 14.8 | 39 | Citations (PDF) |
| 75 | Tumour Cell Heterogeneity | 0.6 | 88 | Citations (PDF) |
| 76 | Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine | 17.2 | 160 | Citations (PDF) |
| 77 | The Barrett’s Gland in Phenotype Space | 6.1 | 26 | Citations (PDF) |
| 78 | A Big Bang model of human colorectal tumor growth | 16.3 | 761 | Citations (PDF) |
| 79 | Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential | 35.1 | 522 | Citations (PDF) |
| 80 | Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview | 0.4 | 236 | Citations (PDF) |
| 81 | Characterization of LGR5 stem cells in colorectal adenomas and carcinomas | 3.7 | 79 | Citations (PDF) |
| 82 | Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis | 4.1 | 59 | Citations (PDF) |
| 83 | Low-Grade Dysplasia in Ulcerative Colitis: Risk Factors for Developing High-Grade Dysplasia or Colorectal Cancer | 0.4 | 117 | Citations (PDF) |
| 84 | Pan-cancer analysis of the extent and consequences of intratumor heterogeneity | 25.6 | 572 | Citations (PDF) |
| 85 | Revealing human intestinal stem cell and crypt dynamics | 2.0 | 8 | Citations (PDF) |
| 86 | Re: Mitochondria and Tumor Progression in Ulcerative Colitis | 5.1 | 0 | Citations (PDF) |
| 87 | Location, location, location! The reality of life for an intestinal stem cell in the crypt | 5.2 | 8 | Citations (PDF) |
| 88 | Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution | 7.7 | 81 | Citations (PDF) |
| 89 | Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells | 5.2 | 10 | Citations (PDF) |
| 90 | Modelling the evolution of genetic instability during tumour progression | 3.3 | 36 | Citations (PDF) |
| 91 | <scp>LRIG1</scp> regulates cadherin‐dependent contact inhibition directing epithelial homeostasis and pre‐invasive squamous cell carcinoma development | 5.2 | 31 | Citations (PDF) |
| 92 | A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts | 14.8 | 73 | Citations (PDF) |
| 93 | Pre‐tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development | 5.2 | 16 | Citations (PDF) |
| 94 | Clonal Selection and Persistence in Dysplastic Barrettʼs Esophagus and Intramucosal Cancers After Failed Radiofrequency Ablation | 0.4 | 22 | Citations (PDF) |
| 95 | What Can Be Learnt about Disease Progression in Breast Cancer Dormancy from Relapse Data? | 2.5 | 8 | Citations (PDF) |
| 96 | Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor | 14.8 | 69 | Citations (PDF) |
| 97 | Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis | 1.0 | 105 | Citations (PDF) |
| 98 | Utilizing DNA Mutations to Trace Epithelial Cell Lineages in Human Tissues | 0.0 | 2 | Citations (PDF) |
| 99 | Resolving the stem-cell debate | 40.1 | 66 | Citations (PDF) |
| 100 | Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue | 1.0 | 46 | Citations (PDF) |
| 101 | The Clonal Origins of Dysplasia From Intestinal Metaplasia in the Human Stomach | 1.0 | 79 | Citations (PDF) |
| 102 | Stem cells and their implications for colorectal cancer | 14.7 | 121 | Citations (PDF) |
| 103 | Field Cancerization in the GI Tract | 2.4 | 29 | Citations (PDF) |
| 104 | The human urothelium consists of multiple clonal units, each maintained by a stem cell | 5.2 | 58 | Citations (PDF) |
| 105 | Clonal architecture of human prostatic epithelium in benign and malignant conditions | 5.2 | 50 | Citations (PDF) |
| 106 | Stem Cells and Inflammation in the Intestine | 0.0 | 7 | Citations (PDF) |
| 107 | A breast cancer meta-analysis of two expression measures of chromosomal instability reveals a relationship with younger age at diagnosis and high risk histopathological variables | 1.7 | 8 | Citations (PDF) |
| 108 | Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why? | 4.2 | 10 | Citations (PDF) |
| 109 | The histogenesis of regenerative nodules in human liver cirrhosis | 11.6 | 86 | Citations (PDF) |
| 110 | Spindles losing their bearings: Does disruption of orientation in stem cells predict the onset of cancer? | 2.3 | 7 | Citations (PDF) |
| 111 | Field defects in DNA repair: is loss of MGMT an initial event in colorectal carcinogenesis? | 14.8 | 1 | Citations (PDF) |
| 112 | Authors' response | 14.8 | 1 | Citations (PDF) |
| 113 | Long-term proton pump induced hypergastrinaemia does induce lineage-specific restitution but not clonal expansion in benign Barrett's oesophagus in vivo | 14.8 | 23 | Citations (PDF) |
| 114 | Breast Cancer Dormancy Can Be Maintained by Small Numbers of Micrometastases | 0.6 | 37 | Citations (PDF) |
| 115 | Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas | 1.0 | 111 | Citations (PDF) |
| 116 | Stem cells and solid cancers | 2.7 | 23 | Citations (PDF) |
| 117 | Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia | 1.0 | 157 | Citations (PDF) |
| 118 | Investigating The Fixation and Spread of Mutations in The Gastrointestinal Epithelium | 2.4 | 4 | Citations (PDF) |
| 119 | Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors | 1.6 | 97 | Citations (PDF) |
| 120 | Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios | 1.6 | 25 | Citations (PDF) |
