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234 peer-reviewed articles • 27,596 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Explainable artificial intelligence in skin cancer recognition: A systematic review
European Journal of Cancer, 2022, 167, 54-69
4.9161Citations (PDF)
2The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics5.350Citations (PDF)
3Uncertainty Estimation in Medical Image Classification: Systematic Review
JMIR Medical Informatics, 2022, 10, e36427
9.470Citations (PDF)
4Den Patienten wirklich verstehen lernen: Real-world-Evidenz aus der „patient journey“0.56Citations (PDF)
5Integrating proteomics into precision oncology
International Journal of Cancer, 2021, 148, 1438-1451
4.325Citations (PDF)
6Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients13.744Citations (PDF)
7Renewed Absence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infections in the Day Care Context in Berlin, January 2021
Clinical Infectious Diseases, 2021, 73, 1944-1945
5.24Citations (PDF)
8Robustness of convolutional neural networks in recognition of pigmented skin lesions
European Journal of Cancer, 2021, 145, 81-91
4.954Citations (PDF)
9Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study
Infection, 2021, 49, 703-714
2.930Citations (PDF)
10Deep learning approach to predict lymph node metastasis directly from primary tumour histology in prostate cancer
BJU International, 2021, 128, 352-360
3.266Citations (PDF)
11The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision
Leukemia, 2021, 35, 2948-2963
7.714Citations (PDF)
12Combining CNN-based histologic whole slide image analysis and patient data to improve skin cancer classification
European Journal of Cancer, 2021, 149, 94-101
4.998Citations (PDF)
13MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer4.923Citations (PDF)
14Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers
Cancer Discovery, 2021, 11, 2780-2795
25.1268Citations (PDF)
15Impact of dexamethasone on SARS-CoV-2 concentration kinetics and antibody response in hospitalized COVID-19 patients: results from a prospective observational study
Clinical Microbiology and Infection, 2021, 27, 1520.e7-1520.e10
5.315Citations (PDF)
16Deutschland krempelt die Ärmel hoch0.01Citations (PDF)
17A time-resolved proteomic and prognostic map of COVID-19
Cell Systems, 2021, 12, 780-794.e7
5.8184Citations (PDF)
18Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study23.3326Citations (PDF)
19Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany
Emerging Infectious Diseases, 2021, 27, 2174-2178
3.877Citations (PDF)
20A benchmark for neural network robustness in skin cancer classification
European Journal of Cancer, 2021, 155, 191-199
4.961Citations (PDF)
21Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts
European Journal of Cancer, 2021, 156, 202-216
4.9239Citations (PDF)
22Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP)
Infection, 2021, 49, 1277-1287
2.937Citations (PDF)
23Deep learning can predict lymph node status directly from histology in colorectal cancer
European Journal of Cancer, 2021, 157, 464-473
4.972Citations (PDF)
24Überdiagnose von Melanomen – Ursachen, Konsequenzen und Lösungsansätze0.60Citations (PDF)
25Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment
Cell, 2020, 182, 1419-1440.e23
33.61,517Citations (PDF)
26Overdiagnosis of melanoma – causes, consequences and solutions0.631Citations (PDF)
27Externe wissenschaftliche Evaluation der ersten Teledermatologie-App ohne direkten Patientenkontakt in Deutschland („Online Hautarzt – AppDoc“)
Hautarzt, 2020, 71, 887-897
1.023Citations (PDF)
28Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)
Infection, 2020, 48, 619-626
2.9105Citations (PDF)
29Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia
Leukemia, 2020, 34, 2785-2789
7.78Citations (PDF)
30COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
Nature Biotechnology, 2020, 38, 970-979
29.81,070Citations (PDF)
31Sequencing of serially passaged measles virus affirms its genomic stability and reveals a nonrandom distribution of consensus mutations
Journal of General Virology, 2020, 101, 399-409
3.38Citations (PDF)
32The German Corona Consensus Dataset (GECCO): a standardized dataset for COVID-19 research in university medicine and beyond3.169Citations (PDF)
33Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data
European Journal of Cancer, 2019, 119, 30-34
4.940Citations (PDF)
34Deep neural networks are superior to dermatologists in melanoma image classification
European Journal of Cancer, 2019, 119, 11-17
4.9362Citations (PDF)
35Systematic outperformance of 112 dermatologists in multiclass skin cancer image classification by convolutional neural networks
European Journal of Cancer, 2019, 119, 57-65
4.9193Citations (PDF)
36Deep learning outperformed 11 pathologists in the classification of histopathological melanoma images
European Journal of Cancer, 2019, 118, 91-96
4.9268Citations (PDF)
37Superior skin cancer classification by the combination of human and artificial intelligence
European Journal of Cancer, 2019, 120, 114-121
4.9309Citations (PDF)
38Enhanced classifier training to improve precision of a convolutional neural network to identify images of skin lesions
PLoS ONE, 2019, 14, e0218713
2.333Citations (PDF)
39Pathologist-level classification of histopathological melanoma images with deep neural networks
European Journal of Cancer, 2019, 115, 79-83
4.9204Citations (PDF)
40A convolutional neural network trained with dermoscopic images performed on par with 145 dermatologists in a clinical melanoma image classification task
European Journal of Cancer, 2019, 111, 148-154
4.9271Citations (PDF)
41Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task
European Journal of Cancer, 2019, 113, 47-54
4.9514Citations (PDF)
42Defective homologous recombination DNA repair as therapeutic target in advanced chordoma13.786Citations (PDF)
43Comparing artificial intelligence algorithms to 157 German dermatologists: the melanoma classification benchmark
European Journal of Cancer, 2019, 111, 30-37
4.9144Citations (PDF)
44Systematic comparative study of computational methods for T-cell receptor sequencing data analysis
Briefings in Bioinformatics, 2019, 20, 222-234
6.620Citations (PDF)
45Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains
Oncogene, 2019, 39, 814-832
6.532Citations (PDF)
46Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia
New England Journal of Medicine, 2018, 378, 1479-1493
34.5661Citations (PDF)
47Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors
Clinical Cancer Research, 2018, 24, 2128-2137
6.8103Citations (PDF)
48Integrative genomic and transcriptomic analysis of leiomyosarcoma13.7284Citations (PDF)
49Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories
Cancer Cell, 2018, 34, 996-1011.e8
33.0299Citations (PDF)
50A Face-Aging Smoking Prevention/Cessation Intervention for Nursery School Students in Germany: An Appearance-Focused Interventional Study2.97Citations (PDF)
51NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer
Cancer Discovery, 2018, 8, 1087-1095
25.1236Citations (PDF)
52Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs
Cell Stem Cell, 2018, 23, 132-146.e9
16.414Citations (PDF)
53Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites4.937Citations (PDF)
54Drug-perturbation-based stratification of blood cancer10.6153Citations (PDF)
55GENE-IS: Time-Efficient and Accurate Analysis of Viral Integration Events in Large-Scale Gene Therapy Data5.534Citations (PDF)
56Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation
OncoImmunology, 2017, 6, e1285992
5.475Citations (PDF)
57Precision oncology based on omics data: The NCT Heidelberg experience4.3164Citations (PDF)
58Succession of transiently active tumor‐initiating cell clones in human pancreatic cancer xenografts
EMBO Molecular Medicine, 2017, 9, 918-932
7.144Citations (PDF)
59Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer
Journal of Experimental Medicine, 2017, 214, 2073-2088
9.332Citations (PDF)
60Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification4.139Citations (PDF)
61Patient-derived xenografts of gastrointestinal cancers are susceptible to rapid and delayed B-lymphoproliferation
International Journal of Cancer, 2017, 140, 1356-1363
4.331Citations (PDF)
62Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation
Human Gene Therapy, 2017, 28, 875-885
3.210Citations (PDF)
63Targeting Fibroblast Growth Factor Receptor 1 for Treatment of Soft-Tissue Sarcoma
Clinical Cancer Research, 2017, 23, 962-973
6.832Citations (PDF)
64Mutant KIT as imatinib-sensitive target in metastatic sinonasal carcinoma
Annals of Oncology, 2017, 28, 142-148
9.933Citations (PDF)
65Shifting cancer care towards Multidisciplinarity: the cancer center certification program of the German cancer society
BMC Cancer, 2017, 17,
2.996Citations (PDF)
66Between Minimal and Greater Than Minimal Risk: How Research Participants and Oncologists Assess Data-Sharing and the Risk of Re-identification in Genomic Research
Philosophy and Technology, 2017, 32, 39-55
3.31Citations (PDF)
67Synergizing genome editing and cancer immunotherapy
Translational Cancer Research, 2017, 6, S969-S972
1.20Citations (PDF)
68Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain3.425Citations (PDF)
69BRAF inhibition in hairy cell leukemia with low-dose vemurafenib
Blood, 2016, 127, 2847-2855
5.0121Citations (PDF)
70Integration of genomics and histology revises diagnosis and enables effective therapy of refractory cancer of unknown primary with PDL1 amplification1.460Citations (PDF)
71In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases
Cell Stem Cell, 2016, 19, 107-119
16.4225Citations (PDF)
72Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
Molecular Therapy, 2016, 24, 570-581
10.2197Citations (PDF)
73Lentiglobin Gene Therapy for Transfusion-Dependent β-Thalassemia: Update from the Northstar Hgb-204 Phase 1/2 Clinical Study
Blood, 2016, 128, 1175-1175
5.018Citations (PDF)
74Interim Results from a Phase 1/2 Clinical Study of Lentiglobin Gene Therapy for Severe Sickle Cell Disease
Blood, 2016, 128, 1176-1176
5.048Citations (PDF)
75Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV4.123Citations (PDF)
76Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation6.416Citations (PDF)
77So rare we need to hunt for them: reframing the ethical debate on incidental findings
Genome Medicine, 2015, 7,
9.619Citations (PDF)
78High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies4.112Citations (PDF)
79The influence of low molecular weight heparin medication on plasma DNA in pregnant women
Prenatal Diagnosis, 2015, 35, 1155-1157
2.357Citations (PDF)
80Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory12.5121Citations (PDF)
81Fanconi Anemia Gene Editing by the CRISPR/Cas9 System
Human Gene Therapy, 2015, 26, 114-126
3.2109Citations (PDF)
82Identification of NY‐BR‐1‐specific CD4+ T cell epitopes using HLA‐transgenic mice
International Journal of Cancer, 2015, 136, 2588-2597
4.36Citations (PDF)
83Cell Cycle Status of CD34+ Hemopoietic Stem Cells Determines Lentiviral Integration in Actively Transcribed and Development-related Genes
Molecular Therapy, 2015, 23, 683-696
10.213Citations (PDF)
84TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice
European Journal of Immunology, 2015, 45, 1524-1534
3.128Citations (PDF)
85Lentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma
Gene Therapy, 2015, 22, 707-720
3.542Citations (PDF)
86Impact of neo-adjuvant Sorafenib treatment on liver transplantation in HCC patients - a prospective, randomized, double-blind, phase III trial
BMC Cancer, 2015, 15,
2.973Citations (PDF)
87High-resolution analysis of the human T-cell receptor repertoire13.7134Citations (PDF)
88Cooperation of BRAFF595L and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling
Leukemia, 2015, 30, 937-946
7.761Citations (PDF)
89Update of Results from the Northstar Study (HGB-204): A Phase 1/2 Study of Gene Therapy for Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex-Vivo with a Lentiviral Beta AT87Q-Globin Vector (LentiGlobin BB305 Drug Product)
Blood, 2015, 126, 201-201
5.017Citations (PDF)
90Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector
Blood, 2015, 126, 202-202
5.031Citations (PDF)
91Cooperative Activity of BRAF F595L and Mutant HRAS in Histiocytic Sarcoma Provides New Insights into Oncogenic BRAF Signaling
Blood, 2015, 126, 1631-1631
5.02Citations (PDF)
92Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant5.512Citations (PDF)
93Integration-deficient Lentiviral Vectors Expressing Codon-optimized R338L Human FIX Restore Normal Hemostasis in Hemophilia B Mice
Molecular Therapy, 2014, 22, 567-574
10.249Citations (PDF)
94Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity12.5533Citations (PDF)
95Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Cancer Cell, 2014, 25, 393-405
33.0730Citations (PDF)
96Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
Nature, 2014, 510, 537-541
37.9438Citations (PDF)
97Artificial riboswitches for gene expression and replication control of DNA and RNA viruses7.5118Citations (PDF)
98CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy
Molecular Therapy, 2014, 22, 1949-1959
10.2275Citations (PDF)
99Transgenic Expression of Human Glial Cell Line-Derived Neurotrophic Factor from Integration-Deficient Lentiviral Vectors is Neuroprotective in a Rodent Model of Parkinson's Disease
Human Gene Therapy, 2014, 25, 631-641
3.222Citations (PDF)
100Vector Integration and Tumorigenesis
Human Gene Therapy, 2014, 25, 475-481
3.226Citations (PDF)
101Uncovering and Dissecting the Genotoxicity of Self-inactivating Lentiviral Vectors In Vivo
Molecular Therapy, 2014, 22, 774-785
10.2183Citations (PDF)
102Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Nature, 2014, 511, 428-434
37.9634Citations (PDF)
103Linear Amplification Mediated PCR – Localization of Genetic Elements and Characterization of Unknown Flanking DNA0.313Citations (PDF)
104Initial Results from the Northstar Study (HGB-204): A Phase 1/2 Study of Gene Therapy for β-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral βΑ-T87Q -Globin Vector (LentiGlobin BB305 Drug Product)
Blood, 2014, 124, 549-549
5.010Citations (PDF)
105Linear Amplification Mediated PCR – Localization of Genetic Elements and Characterization of Unknown Flanking DNA0.30Citations (PDF)
106Next-generation sequencing of cancer consensus genes in lymphoma
Leukemia and Lymphoma, 2013, 54, 1831-1835
1.410Citations (PDF)
107Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Nature Genetics, 2013, 45, 927-932
25.2795Citations (PDF)
108Personalisierte Medizin und Informed Consent: Klinische und ethische Erwägungen im Rahmen der Entwicklung einer Best Practice Leitlinie für die biobankbasierte Ganzgenomforschung in der Onkologie
Ethik in Der Medizin, 2013, 25, 195-203
0.83Citations (PDF)
109Granulocyte-Macrophage Colony-Stimulating Factor-Armed Oncolytic Measles Virus Is an Effective Therapeutic Cancer Vaccine
Human Gene Therapy, 2013, 24, 644-654
3.291Citations (PDF)
110Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
Science, 2013, 341,
36.21,118Citations (PDF)
111Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
Science, 2013, 341,
36.2977Citations (PDF)
112Chemovirotherapy of Malignant Melanoma with a Targeted and Armed Oncolytic Measles Virus2.336Citations (PDF)
113Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient
Stem Cells, 2013, 31, 1785-1794
3.228Citations (PDF)
114Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer
Cancer Cell, 2013, 23, 159-170
33.0314Citations (PDF)
115Lentiviral vector–based insertional mutagenesis identifies genes associated with liver cancer
Nature Methods, 2013, 10, 155-161
24.6102Citations (PDF)
116TALEN-based Gene Correction for Epidermolysis Bullosa
Molecular Therapy, 2013, 21, 1151-1159
10.2249Citations (PDF)
117A largely random AAV integration profile after LPLD gene therapy
Nature Medicine, 2013, 19, 889-891
33.0187Citations (PDF)
118From Bench to Bedside: Preclinical Evaluation of a Self-Inactivating Gammaretroviral Vector for the Gene Therapy of X-linked Chronic Granulomatous Disease3.622Citations (PDF)
119The Fetal Mouse Is a Sensitive Genotoxicity Model That Exposes Lentiviral-associated Mutagenesis Resulting in Liver Oncogenesis
Molecular Therapy, 2013, 21, 324-337
10.222Citations (PDF)
120Safety and Liver Transduction Efficacy of rAAV5- cohPBGD in Nonhuman Primates: A Potential Therapy for Acute Intermittent Porphyria
Human Gene Therapy, 2013, 24, 1007-1017
3.260Citations (PDF)
121Preclinical Safety and Efficacy of Human CD34+ Cells Transduced With Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome
Molecular Therapy, 2013, 21, 175-184
10.276Citations (PDF)
122Continued Response Off Treatment After BRAF Inhibition in Refractory Hairy Cell Leukemia
Journal of Clinical Oncology, 2013, 31, e300-e303
16.968Citations (PDF)
123Hematopoietic Stem Cell Gene Therapy For Wiskott- Aldrich Syndrome
Blood, 2013, 122, 718-718
5.02Citations (PDF)
124Long-Term Immunological Profile and T Cell Dynamics In Patients Treated With Allogeneic Transplantation and TK-Cells For Hematological Malignancies
Blood, 2013, 122, 165-165
5.00Citations (PDF)
125Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver
Molecular Therapy, 2012, 20, 1177-1186
10.2106Citations (PDF)
126BRAF Inhibition in Refractory Hairy-Cell Leukemia
New England Journal of Medicine, 2012, 366, 2038-2040
34.5246Citations (PDF)
127Stable Long-Term Blood Formation by Stem Cells in Murine Steady-State Hematopoiesis
Stem Cells, 2012, 30, 1961-1970
3.211Citations (PDF)
128Integration of retroviral vectors5.225Citations (PDF)
129Bioinformatic Clonality Analysis of Next-Generation Sequencing-Derived Viral Vector Integration Sites
Human Gene Therapy Methods, 2012, 23, 111-118
4.043Citations (PDF)
130Extensive Methylation of Promoter Sequences Silences Lentiviral Transgene Expression During Stem Cell Differentiation In Vivo
Molecular Therapy, 2012, 20, 1014-1021
10.2106Citations (PDF)
131Dissecting the genomic complexity underlying medulloblastoma
Nature, 2012, 488, 100-105
37.9834Citations (PDF)
132Translationale Onkologie – Effiziente Umsetzung onkologischer Grundlagenforschung0.23Citations (PDF)
133Continued Response off Treatment After BRAF Inhibition in Refractory Hairy Cell Leukemia
Blood, 2012, 120, 4600-4600
5.00Citations (PDF)
134Overexpression of EVI1 Causes Genomic Instability and Cell Cycle Arrest in Hematopoietic Cells.
Blood, 2012, 120, 2398-2398
5.00Citations (PDF)
135Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases
Cell Stem Cell, 2011, 9, 357-365
16.4290Citations (PDF)
136An unbiased genome-wide analysis of zinc-finger nuclease specificity
Nature Biotechnology, 2011, 29, 816-823
29.8511Citations (PDF)
137Analyzing the Number of Common Integration Sites of Viral Vectors – New Methods and Computer Programs
PLoS ONE, 2011, 6, e24247
2.324Citations (PDF)
138Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection
Blood, 2011, 117, 5332-5339
5.0232Citations (PDF)
139Correction of Murine SCID-X1 by Lentiviral Gene Therapy Using a Codon-optimized IL2RG Gene and Minimal Pretransplant Conditioning
Molecular Therapy, 2011, 19, 1867-1877
10.242Citations (PDF)
140Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk
Hepatology, 2011, 53, 1696-1707
10.1131Citations (PDF)
141Integration profile of retroviral vector in gene therapy treated patients is cell‐specific according to gene expression and chromatin conformation of target cell
EMBO Molecular Medicine, 2011, 3, 89-101
7.1101Citations (PDF)
142Stem Cell Gene Therapy for Fanconi Anemia: Report from the 1st International Fanconi Anemia Gene Therapy Working Group Meeting
Molecular Therapy, 2011, 19, 1193-1198
10.247Citations (PDF)
143Stable Human FIX Expression After 0.9G Intrauterine Gene Transfer of Self-complementary Adeno-associated Viral Vector 5 and 8 in Macaques
Molecular Therapy, 2011, 19, 1950-1960
10.278Citations (PDF)
144Lentiviral Vector Integration Profiles Differ in Rodent Postmitotic Tissues
Molecular Therapy, 2011, 19, 703-710
10.252Citations (PDF)
145Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy
Molecular Therapy, 2011, 19, 2031-2039
10.248Citations (PDF)
146MicroRNA-sensitive Oncolytic Measles Viruses for Cancer-specific Vector Tropism
Molecular Therapy, 2011, 19, 1097-1106
10.297Citations (PDF)
147Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs
Molecular Therapy, 2011, 19, 1287-1294
10.215Citations (PDF)
148Clonal Inventory Screens Uncover Monoclonality Following Serial Transplantation of MGMT P140K -Transduced Stem Cells and Dose-Intense Chemotherapy
Human Gene Therapy, 2011, 22, 697-710
3.217Citations (PDF)
149Retroviral Gene Therapy for X-linked Chronic Granulomatous Disease: Results From Phase I/II Trial
Molecular Therapy, 2011, 19, 2092-2101
10.299Citations (PDF)
150Retroviral Vectors: Post Entry Events and Genomic Alterations
Viruses, 2011, 3, 429-455
3.246Citations (PDF)
151Efficacy of Gene Therapy for Wiskott-Aldrich-Syndrome
Blood, 2011, 118, 165-165
5.02Citations (PDF)
152Deregulated EVI1 Expression Leads to Genomic Instability and G1 Cell Cycle Arrest
Blood, 2011, 118, 2431-2431
5.00Citations (PDF)
153Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
Nature Medicine, 2010, 16, 198-204
33.0775Citations (PDF)
154The Inherent Differentiation Program of Short-Term Hematopoietic Repopulating Cells Changes During Human Ontogeny
Stem Cells and Development, 2010, 19, 621-628
2.03Citations (PDF)
155Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factors
Molecular Therapy, 2010, 18, 2139-2145
10.238Citations (PDF)
156Stem-Cell Gene Therapy for the Wiskott–Aldrich Syndrome
New England Journal of Medicine, 2010, 363, 1918-1927
34.5534Citations (PDF)
157Retroviral Vectors for Gene Therapy
Future Microbiology, 2010, 5, 1507-1523
2.046Citations (PDF)
15810-Year stability of clinical-grade serum-free γ-retroviral vector-containing medium
Gene Therapy, 2010, 18, 210-212
3.54Citations (PDF)
159Thérapie génique de l’adrénoleucodystrophie liée à l’X par transfert du gène dans les cellules souches hématopoïétiques à l’aide d’un vecteur lentiviral0.110Citations (PDF)
160High-Definition Mapping of Retroviral Integration Sites Defines the Fate of Allogeneic T Cells After Donor Lymphocyte Infusion
PLoS ONE, 2010, 5, e15688
2.342Citations (PDF)
161Uncovering Haematopoietic System Dynamics and Single Multipotent Progenitors Activity In Vivo In Humans by Retroviral Tagging.
Blood, 2010, 116, 2611-2611
5.00Citations (PDF)
162Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells
Nature Medicine, 2009, 15, 285-292
33.0268Citations (PDF)
163Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
Science, 2009, 326, 818-823
36.21,472Citations (PDF)
164The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy10.6531Citations (PDF)
165Inhibition of HIF1A Signaling by a Novel Class of Sulfonanilides for Targeted Treatment of Multiple Myeloma.
Blood, 2009, 114, 2856-2856
5.02Citations (PDF)
166In Vivo Lentiviral Marking Demonstrates Long-Term Myeloid and Lymphoid Lineage Contribution of Individual Hematopoietic Stem Cell Clones to Murine Steady-State Hematopoiesis.
Blood, 2009, 114, 813-813
5.00Citations (PDF)
167Adeno-Associated Virus Vector Genomes Persist as Episomal Chromatin in Primate Muscle
Journal of Virology, 2008, 82, 7875-7885
3.6279Citations (PDF)
168Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
Journal of Clinical Investigation, 2008, 118, 3143-3150
10.61,211Citations (PDF)
169Hematopoietic Stem Cell Gene Therapy Trial with Lentiviral Vector in X-Linked Adrenoleukodystrophy
Blood, 2008, 112, 821-821
5.03Citations (PDF)
170Comprehensive and Unbiased Integration Site Analysis in Clinical Gene Therapy.
Blood, 2008, 112, 2351-2351
5.00Citations (PDF)
171Hematopoietic Activity of Human Short Term Repopulating Cells in Mobilized Peripheral Blood Cell Transplants Is Restricted to the First 5Months after Transplantation.
Blood, 2008, 112, 1386-1386
5.00Citations (PDF)
172Non-Random Lentiviral Vector Insertions in Bone Marrow Progenitors from Fanconi Anemia Patients
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173Stem Cell Collection and Gene Transfer in Fanconi Anemia
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174Importance of Murine Study Design for Testing Toxicity of Retroviral Vectors in Support of Phase I Trials
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175Hot spots of retroviral integration in human CD34+ hematopoietic cells
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176Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
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177Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo
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178Hematopoietic Stem Cell Gene Therapy for Wiskott-Aldrich Syndrome.
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179Real-Time Definition of Non-Randomness in the Distribution of Genomic Events
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180The Clonal Inventory of Gene Corrected Hematopoiesis in Three Successful Clinical Gene Therapy Trials
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181Phase I/II Gene Therapy Study for Chronic Granulomatous Disease: Results, Lessons and Perspectives.
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182A Hybrid Vector for Ligand-Directed Tumor Targeting and Molecular Imaging
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183Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity
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184Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque
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185Therapeutic gene causing lymphoma
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186Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
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187Effective gene therapy with nonintegrating lentiviral vectors
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188Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
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189Fragile sites are preferential targets for integrations of MLV vectors in gene therapy
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190Lentiviral vectors pseudotyped with murine ecotropic envelope: Increased biosafety and convenience in preclinical research
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191Bone marrow-derived cells contribute to infarct remodelling
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19297. Translational Studies toward Optimizing In Vivo Bone Marrow Stem Cell Gene Transfer Using Lentiviral Vector
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193In Vivo Gene Transfer into Adult Stem Cells in Unconditioned Mice by in Situ Delivery of a Lentiviral Vector
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194Low-dose total body irradiation causes clonal fluctuation of primate hematopoietic stem and progenitor cells
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195Clonal evidence for the transduction of CD34+ cells with lymphomyeloid differentiation potential and self-renewal capacity in the SCID-X1 gene therapy trial
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196Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients
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197Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis
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198Failure of SCID-X1 gene therapy in older patients
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199Evidence of similar effects of short-term culture on the initial repopulating activity of mobilized peripheral blood transplants assessed in NOD/SCID-β2microglobulinnull mice and in autografted patients
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200Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34+ cells
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201Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice
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202Long-Term Clinical and Molecular Follow-up of Large Animals Receiving Retrovirally Transduced Stem and Progenitor Cells: No Progression to Clonal Hematopoiesis or Leukemia
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203LMO2and Gene Therapy for Severe Combined Immunodeficiency
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204Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells
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205Chance or necessity? Insertional Mutagenesis in Gene Therapy and Its Consequences
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206Stem cell clonality and genotoxicity in hematopoietic cells: Gene activation side effects should be avoidable
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207Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
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208Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates
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209Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates
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210Efficient Characterization of Retro‐, Lenti‐, and Foamyvector‐Transduced Cell Populations by High‐Accuracy Insertion Site Sequencing4.022Citations (PDF)
211A Serious Adverse Event after Successful Gene Therapy for X-Linked Severe Combined Immunodeficiency34.51,820Citations (PDF)
212Comparison of Three Retroviral Vector Systems for Transduction of Nonobese Diabetic/Severe Combined Immunodeficiency Mice Repopulating Human CD34+Cord Blood Cells
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213Retrovirally transduced muscle-derived cells contribute to hematopoiesis at very low levels in the nonhuman primate model
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214Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis
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215Side effects of retroviral gene transfer into hematopoietic stem cells
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217Methylguanine methyltransferase–mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model
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219Polyclonal long-term repopulating stem cell clones in a primate model
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221Molecular Evidence of Lentiviral Vector-Mediated Gene Transfer into Human Self-Renewing, Multi-potent, Long-Term NOD/SCID Repopulating Hematopoietic Cells
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231Long-Term Persistence of Canine Hematopoietic Cells Genetically Marked by Retrovirus Vectors
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