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139 papers • 60,263 citations • Sorted by year • Download PDF (PDF by citations)
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1STING induces HOIP-mediated synthesis of M1 ubiquitin chains to stimulate NF-κB signaling
EMBO Journal, 2025, 44, 141-165
7.40Citations (PDF)
2Mitochondrial YME1L1 governs unoccupied protein translocase channels
Nature Cell Biology, 2025, 27, 309-321
10.51Citations (PDF)
3Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
PLoS Genetics, 2023, 19, e1010828
3.311Citations (PDF)
4Nix interacts with <scp>WIPI2</scp> to induce mitophagy
EMBO Journal, 2023, 42,
7.414Citations (PDF)
5Acute Manipulation of Outer Membrane Phospholipid Composition Directly Alters Mitochondrial Dynamics and Ultrastructure
FASEB Journal, 2022, 36,
0.70Citations (PDF)
6VPS13D promotes peroxisome biogenesis4.847Citations (PDF)
7Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes4.843Citations (PDF)
8Mitochondrial Quality Control and Restraining Innate Immunity10.180Citations (PDF)
9Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
Brain, 2020, 143, 3041-3051
8.9127Citations (PDF)
10Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain
Molecular Cell, 2020, 80, 779-795.e10
14.291Citations (PDF)
11Two different axes CALCOCO2-RB1CC1 and OPTN-ATG9A initiate PRKN-mediated mitophagy
Autophagy, 2020, 16, 2105-2107
13.828Citations (PDF)
12Ubiquitin signaling in neurodegenerative diseases: an autophagy and proteasome perspective13.754Citations (PDF)
13ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer4.858Citations (PDF)
14STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain4.8107Citations (PDF)
15Mitochondria—Striking a balance between host and endosymbiont
Science, 2019, 365,
38.2137Citations (PDF)
16PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis
Cell Reports, 2019, 29, 225-235.e5
6.462Citations (PDF)
17Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1
Molecular Cell, 2019, 73, 1028-1043.e5
14.2113Citations (PDF)
18Neurolastin, a dynamin family GTPase, translocates to mitochondria upon neuronal stress and alters mitochondrial morphology in vivo
Journal of Biological Chemistry, 2019, 294, 11498-11512
2.31Citations (PDF)
19Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
Molecular Cell, 2019, 74, 347-362.e6
14.2313Citations (PDF)
20Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
Current Biology, 2018, 28, R170-R185
3.91,383Citations (PDF)
21Parkin mediates mitophagy during beige-to-white fat conversion
Science Signaling, 2018, 11,
5.514Citations (PDF)
22Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ
PLoS Genetics, 2018, 14, e1007805
3.329Citations (PDF)
23Active state of Parkin6.43Citations (PDF)
24PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol
BMC Biology, 2018, 16,
4.0233Citations (PDF)
25Parkin and PINK1 mitigate STING-induced inflammation
Nature, 2018, 561, 258-262
40.1954Citations (PDF)
26Author response: Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis
2018, ,
0Citations (PDF)
27Fluorescence‐based <scp>ATG</scp>8 sensors monitor localization and function of <scp>LC</scp>3/<scp>GABARAP</scp> proteins
EMBO Journal, 2017, 36, 549-564
7.438Citations (PDF)
28Mitochondrial fission facilitates the selective mitophagy of protein aggregates
Journal of Cell Biology, 2017, 216, 3231-3247
4.8356Citations (PDF)
29Author response: Endosomal Rab cycles regulate Parkin-mediated mitophagy
2017, ,
0Citations (PDF)
30Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria7.7556Citations (PDF)
31The Mitochondrial Basis of Aging
Molecular Cell, 2016, 61, 654-666
14.21,006Citations (PDF)
32Mitochondrial Function, Biology, and Role in Disease
Circulation Research, 2016, 118, 1960-1991
12.8348Citations (PDF)
33Form follows function for mitochondria
Nature, 2016, 530, 288-289
40.138Citations (PDF)
34Characterization of the membrane-inserted C-terminus of cytoprotective BCL-XL1.317Citations (PDF)
35Chemogenomic Profiling of Endogenous <i>PARK2</i> Expression Using a Genome-Edited Coincidence Reporter
ACS Chemical Biology, 2015, 10, 1188-1197
3.944Citations (PDF)
36The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
Neuron, 2015, 85, 257-273
12.81,629Citations (PDF)
37MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5
Journal of Cell Biology, 2015, 210, 435-450
4.8225Citations (PDF)
38Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
Neuron, 2015, 87, 371-381
12.8276Citations (PDF)
39Conformation of BCL-XL upon Membrane Integration
Journal of Molecular Biology, 2015, 427, 2262-2270
4.249Citations (PDF)
40The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
Nature, 2015, 524, 309-314
40.12,000Citations (PDF)
41Mutations in Fis1 disrupt orderly disposal of defective mitochondria2.5168Citations (PDF)
42PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
Journal of Cell Biology, 2014, 205, 143-153
4.8999Citations (PDF)
43Self and Nonself: How Autophagy Targets Mitochondria and Bacteria
Cell Host and Microbe, 2014, 15, 403-411
15.2233Citations (PDF)
44Author response: Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
2014, ,
2Citations (PDF)
45Sequestration and autophagy of mitochondria do not cut proteins across the board7.75Citations (PDF)
46Involvement of mitochondrial dynamics in the segregation of mitochondrial matrix proteins during stationary phase mitophagy14.187Citations (PDF)
47High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
Nature, 2013, 504, 291-295
40.1286Citations (PDF)
48PINK1 rendered temperature sensitive by disease-associated and engineered mutations
Human Molecular Genetics, 2013, 22, 2572-2589
3.122Citations (PDF)
49Mitochondrial Disease: mtDNA and Protein Segregation Mysteries in iPSCs
Current Biology, 2013, 23, R1052-R1054
3.99Citations (PDF)
50PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
Journal of Cell Biology, 2013, 200, 163-172
4.8203Citations (PDF)
51Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy
Molecular and Cellular Biology, 2013, 33, 3675-3688
2.583Citations (PDF)
52The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
Autophagy, 2013, 9, 1750-1757
13.8327Citations (PDF)
53PINK1 is degraded through the N-end rule pathway
Autophagy, 2013, 9, 1758-1769
13.8507Citations (PDF)
54Mitophagy as a quality control mechanism in Saccharomyces cerevisiae
FASEB Journal, 2013, 27,
0.70Citations (PDF)
55PINK1- and Parkin-mediated mitophagy at a glance
Journal of Cell Science, 2012, 125, 795-799
3.2468Citations (PDF)
56Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism7.4267Citations (PDF)
57Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling
Nature Methods, 2012, 9, 303-309
14.596Citations (PDF)
58Structural mechanism of Bax inhibition by cytomegalovirus protein vMIA7.752Citations (PDF)
59Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
Nature Cell Biology, 2012, 14, 575-583
10.5327Citations (PDF)
60Mitochondrial Fission, Fusion, and Stress
Science, 2012, 337, 1062-1065
38.22,667Citations (PDF)
61Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Developmental Cell, 2012, 22, 320-333
7.8522Citations (PDF)
62Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 2012, 8, 445-544
13.82,928Citations (PDF)
63Damage control — How the PINK1/Parkin pathway can regulate removal of impaired mitochondria by autophagy0.60Citations (PDF)
64Balancing cell growth and death4.210Citations (PDF)
65Mitochondrial Dynamics and Apoptosis
2011, , 109-138
3Citations (PDF)
66Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
Cell, 2011, 145, 104-116
35.1496Citations (PDF)
67Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics
Developmental Cell, 2011, 21, 92-101
7.81,141Citations (PDF)
68The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
Molecular Cell, 2011, 41, 150-160
14.2192Citations (PDF)
69Hsp90-Cdc37 Chaperone Complex Regulates Ulk1- and Atg13-Mediated Mitophagy
Molecular Cell, 2011, 43, 572-585
14.2202Citations (PDF)
70Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation4.2205Citations (PDF)
71Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control6.4311Citations (PDF)
72A Systematic Search for Endoplasmic Reticulum (ER) Membrane-associated RING Finger Proteins Identifies Nixin/ZNRF4 as a Regulator of Calnexin Stability and ER Homeostasis
Journal of Biological Chemistry, 2011, 286, 8633-8643
2.352Citations (PDF)
73Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
Journal of Clinical Investigation, 2011, 121, 3701-3712
9.1172Citations (PDF)
74Role of the mitochondrial kinase Pink1 in Parkin recruitment and mitophagy0.60Citations (PDF)
75IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation
EMBO Journal, 2010, 29, 1458-1471
7.467Citations (PDF)
76Mitochondrial fission and fusion
Essays in Biochemistry, 2010, 47, 85-98
5.3207Citations (PDF)
77Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells
Journal of Cell Biology, 2010, 191, 1141-1158
4.8878Citations (PDF)
78Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells7.7277Citations (PDF)
79Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1
Journal of Cell Science, 2010, 123, 619-626
3.2194Citations (PDF)
80p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
Autophagy, 2010, 6, 1090-1106
13.8658Citations (PDF)
81Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Journal of Cell Biology, 2010, 191, 933-942
4.81,057Citations (PDF)
82Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Journal of Cell Biology, 2010, 191, 1367-1380
4.81,134Citations (PDF)
83PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
PLoS Biology, 2010, 8, e1000298
5.22,294Citations (PDF)
84Mechanisms of mitophagy31.42,577Citations (PDF)
85Parkin-induced mitophagy in the pathogenesis of Parkinson disease
Autophagy, 2009, 5, 706-708
13.8194Citations (PDF)
86Bax Activates Endophilin B1 Oligomerization and Lipid Membrane Vesiculation
Journal of Biological Chemistry, 2009, 284, 34390-34399
2.342Citations (PDF)
87SLP-2 is required for stress-induced mitochondrial hyperfusion
EMBO Journal, 2009, 28, 1589-1600
7.4612Citations (PDF)
88The Role of Mitochondria in Apoptosis
Annual Review of Genetics, 2009, 43, 95-118
7.71,520Citations (PDF)
89Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Journal of Cell Biology, 2008, 183, 795-803
4.83,197Citations (PDF)
90Role of the Ubiquitin Conjugation System in the Maintenance of Mitochondrial Homeostasis4.565Citations (PDF)
91The BCL-2 protein family: opposing activities that mediate cell death31.43,744Citations (PDF)
92Endosome fusion induced by diphtheria toxin translocation domain7.712Citations (PDF)
93Mitochondrial dynamics and apoptosis
Genes and Development, 2008, 22, 1577-1590
4.81,039Citations (PDF)
94Cytomegalovirus Proteins vMIA and m38.5 Link Mitochondrial Morphogenesis to Bcl-2 Family Proteins
Journal of Virology, 2008, 82, 6232-6243
3.670Citations (PDF)
95OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion
Brain, 2008, 131, 352-367
8.9281Citations (PDF)
96Mitochondrial Fission and Fusion Mediators, hFis1 and OPA1, Modulate Cellular Senescence
Journal of Biological Chemistry, 2007, 282, 22977-22983
2.3235Citations (PDF)
97The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
Journal of Cell Biology, 2007, 178, 71-84
4.8403Citations (PDF)
98Role of Mitochondrial Remodeling in Programmed Cell Death in Drosophila melanogaster
Developmental Cell, 2007, 12, 807-816
7.8109Citations (PDF)
99Outer Mitochondrial Membrane Protein Degradation by the Proteasome1.063Citations (PDF)
100State of GTPase cycle dictates mobility and localization of large mitochondrial GTPases, Mfn1 and 2
FASEB Journal, 2007, 21,
0.70Citations (PDF)
101Role of Bax and Bak in mitochondrial morphogenesis
Nature, 2006, 443, 658-662
40.1549Citations (PDF)
102Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
EMBO Journal, 2006, 25, 3900-3911
7.4580Citations (PDF)
103How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?4.2234Citations (PDF)
104Mitochondrial fission in apoptosis31.4660Citations (PDF)
105Loss of Bif-1 Suppresses Bax/Bak Conformational Change and Mitochondrial Apoptosis
Molecular and Cellular Biology, 2005, 25, 9369-9382
2.5161Citations (PDF)
106Bid, but Not Bax, Regulates VDAC Channels
Journal of Biological Chemistry, 2004, 279, 13575-13583
2.3166Citations (PDF)
107Endophilin B1 is required for the maintenance of mitochondrial morphology
Journal of Cell Biology, 2004, 166, 1027-1039
4.8221Citations (PDF)
108Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria7.7176Citations (PDF)
109Bcl-xL sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
EMBO Journal, 2004, 23, 2146-2155
7.4139Citations (PDF)
110Roles of the Mammalian Mitochondrial Fission and Fusion Mediators Fis1, Drp1, and Opa1 in Apoptosis
Molecular Biology of the Cell, 2004, 15, 5001-5011
2.5892Citations (PDF)
111Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis
Journal of Cell Biology, 2004, 164, 493-499
4.8376Citations (PDF)
112Drp-1-Dependent Division of the Mitochondrial Network Blocks Intraorganellar Ca2+ Waves and Protects against Ca2+-Mediated Apoptosis
Molecular Cell, 2004, 16, 59-68
14.2413Citations (PDF)
113The Solution Structure of Human Mitochondria Fission Protein Fis1 Reveals a Novel TPR-like Helix Bundle
Journal of Molecular Biology, 2003, 334, 445-458
4.2132Citations (PDF)
114Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization
EMBO Journal, 2003, 22, 4385-4399
7.4373Citations (PDF)
115JNK-Mediated BIM Phosphorylation Potentiates BAX-Dependent Apoptosis
Neuron, 2003, 38, 899-914
12.8454Citations (PDF)
116Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells
Journal of Cell Science, 2003, 116, 2763-2774
3.2357Citations (PDF)
117The permeability transition pore signals apoptosis by directing Bax translocation and multimerization
FASEB Journal, 2002, 16, 607-609
0.7222Citations (PDF)
118Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
Journal of Cell Biology, 2002, 159, 931-938
4.8706Citations (PDF)
119The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
Developmental Cell, 2001, 1, 515-525
7.81,503Citations (PDF)
120Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis
Journal of Cell Biology, 2001, 153, 1265-1276
4.8402Citations (PDF)
121Title is missing!2.7137Citations (PDF)
122p38 Map Kinase Mediates Bax Translocation in Nitric Oxide–Induced Apoptosis in Neurons
Journal of Cell Biology, 2000, 150, 335-348
4.8353Citations (PDF)
123Structure of Bax
Cell, 2000, 103, 645-654
35.1957Citations (PDF)
124Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction
Nature Biotechnology, 1999, 17, 265-270
18.165Citations (PDF)
125Title is missing!
Journal of Biomolecular NMR, 1999, 15, 343-344
2.02Citations (PDF)
126Conformation of the Bax C-terminus regulates subcellular location and cell death
EMBO Journal, 1999, 18, 2330-2341
7.4635Citations (PDF)
127The role of 2′-5′ oligoadenylate-activated ribonuclease L in apoptosis13.7160Citations (PDF)
128Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations
Journal of Biological Chemistry, 1998, 273, 10777-10783
2.3445Citations (PDF)
129Movement of Bax from the Cytosol to Mitochondria during Apoptosis
Journal of Cell Biology, 1997, 139, 1281-1292
4.81,585Citations (PDF)
130A Study of the Interferon Antiviral Mechanism: Apoptosis Activation by the 2–5A System8.1234Citations (PDF)
131Nonionic Detergents Induce Dimerization among Members of the Bcl-2 Family
Journal of Biological Chemistry, 1997, 272, 13829-13834
2.3517Citations (PDF)
132Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumors
Nature Medicine, 1997, 3, 1362-1368
25.6434Citations (PDF)
133Role of the N Terminus in RNase A Homologues: Differences in Catalytic Activity, Ribonuclease Inhibitor Interaction and Cytotoxicity
Journal of Molecular Biology, 1996, 257, 992-1007
4.2178Citations (PDF)
134In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum
Neuron, 1993, 11, 621-632
12.8311Citations (PDF)
135Cytotoxic onconase and ribonuclease a chimeras: comparison andin vitrocharacterization
Drug Delivery, 1993, 1, 3-10
7.923Citations (PDF)
136Apoptosis and DNA degradation induced by 1-methyl-4-phenylpyridinium in neurons2.1210Citations (PDF)
137Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
ELife, 0, 3,
1.6239Citations (PDF)
138Endosomal Rab cycles regulate Parkin-mediated mitophagy
ELife, 0, 7,
1.6115Citations (PDF)
139Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis
ELife, 0, 8,
1.675Citations (PDF)