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276 peer-reviewed articles • 33,572 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Sex differences in murine MASH induced by a fructose-palmitate-cholesterol-enriched diet
JHEP Reports, 2025, 7, 101222
4.511Citations (PDF)
2Mechanistic underpinnings of AGEs-RAGE via DIAPH1 in ischemic, diabetic, and failing hearts3.57Citations (PDF)
3Negative cooperativity regulates ligand activation of DIAPH1 and other diaphanous related formins4.45Citations (PDF)
4Variations in weight loss and glycemic outcomes after sleeve gastrectomy by race and ethnicity
Obesity, 2025, 33, 1567-1579
4.01Citations (PDF)
5The RAGE/DIAPH1 axis: mediator of obesity and proposed biomarker of human cardiometabolic disease
Cardiovascular Research, 2024, 119, 2813-2824
5.514Citations (PDF)
6RAGE/DIAPH1 and atherosclerosis through an evolving lens: Viewing the cell from the “Inside – Out”
Atherosclerosis, 2024, 394, 117304
1.59Citations (PDF)
7Continuous glucose monitoring captures glycemic variability in obesity after sleeve gastrectomy: A prospective cohort study1.94Citations (PDF)
8Cardiometabolic disease: linking pathogenic mechanisms to therapeutic opportunities
Cardiovascular Research, 2024, 119, 2771-2773
5.57Citations (PDF)
9Introducing Socrates’ Corner to ATVB Journal: Critical Appraisals of Animal Models of Disease6.01Citations (PDF)
10DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice4.418Citations (PDF)
11Pharmacological antagonism of receptor for advanced glycation end products signaling promotes thermogenesis, healthful body mass and composition, and metabolism in mice
Obesity, 2023, 31, 1825-1843
4.014Citations (PDF)
12Involvement of the Receptor for Advanced Glycation End Products (RAGE) in high fat-high sugar diet-induced anhedonia in rats
Physiology and Behavior, 2023, 271, 114337
2.27Citations (PDF)
13Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity2.24Citations (PDF)
14DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress13.749Citations (PDF)
15Neuronal–glial communication perturbations in murine SOD1G93A spinal cord4.424Citations (PDF)
16Soluble Receptor for Advanced Glycation End Products (sRAGE) Isoforms Predict Changes in Resting Energy Expenditure in Adults with Obesity during Weight Loss0.212Citations (PDF)
17The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications4.426Citations (PDF)
18Glycation and a Spark of ALEs (Advanced Lipoxidation End Products) – Igniting RAGE/Diaphanous-1 and Cardiometabolic Disease2.418Citations (PDF)
19Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection6.026Citations (PDF)
20Inflammation Meets Metabolism Roles: for the Receptor for Advanced Glycation End Products Axis in Cardiovascular Disease
Immunometabolism, 2021, 3,
2.820Citations (PDF)
21Aldose Reductase: An Emerging Target for Development of Interventions for Diabetic Cardiovascular Complications3.893Citations (PDF)
22MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging6.021Citations (PDF)
23Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner9.032Citations (PDF)
24Diabetes and Cardiovascular Complications: The Epidemics Continue2.919Citations (PDF)
25AGE/RAGE/DIAPH1 axis is associated with immunometabolic markers and risk of insulin resistance in subcutaneous but not omental adipose tissue in human obesity3.025Citations (PDF)
26Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome
Nature Microbiology, 2021, 6, 1245-1258
16.0174Citations (PDF)
27Silencing Myeloid Netrin-1 Induces Inflammation Resolution and Plaque Regression
Circulation Research, 2021, 129, 530-546
13.143Citations (PDF)
28A pilot open-label study of aldose reductase inhibition with AT-001 (caficrestat) in patients hospitalized for COVID-19 infection: Results from a registry-based matched-control analysis3.013Citations (PDF)
29Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice12.574Citations (PDF)
30Advanced Glycation End Products: Building on the Concept of the “Common Soil” in Metabolic Disease
Endocrinology, 2020, 161,
2.5164Citations (PDF)
31Annual Report on Sex in Preclinical Studies6.010Citations (PDF)
32RAGE Mediates Cholesterol Efflux Impairment in Macrophages Caused by Human Advanced Glycated Albumin4.415Citations (PDF)
33Chronic low-dose rapamycin treatment fine tunes cardioprotective signalling in ischaemia-reperfused diabetic hearts
Cardiovascular Research, 2020, 116, 2038-2039
5.50Citations (PDF)
34Receptor for Advanced Glycation End Products is Involved in Platelet Hyperactivation and Arterial Thrombosis during Chronic Kidney Disease
Thrombosis and Haemostasis, 2020, 120, 1300-1312
4.111Citations (PDF)
35Multiomics of World Trade Center Particulate Matter–induced Persistent Airway Hyperreactivity. Role of Receptor for Advanced Glycation End Products3.815Citations (PDF)
36An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation
Circulation Research, 2020, 126, 1565-1589
13.124Citations (PDF)
37Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity
Circulation Research, 2020, 126, 1590-1612
13.166Citations (PDF)
38S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus6.092Citations (PDF)
39Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models2.4192Citations (PDF)
40RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism
JCI Insight, 2020, 5,
5.460Citations (PDF)
41Incense Burning is Associated with Human Oral Microbiota Composition3.416Citations (PDF)
42A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis
Cell Reports, 2019, 28, 773-791.e7
6.350Citations (PDF)
43Metabolism, Obesity, and Diabetes Mellitus6.018Citations (PDF)
44Metabolic dysfunction in Emirati subjects in Abu Dhabi: Relationship to levels of soluble RAGEs1.04Citations (PDF)
45The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system
Neurochemistry International, 2019, 126, 154-164
3.564Citations (PDF)
46The rationale and design of the personal diet study, a randomized clinical trial evaluating a personalized approach to weight loss in individuals with pre-diabetes and early-stage type 2 diabetes1.625Citations (PDF)
47Diabetes Mellitus and Cardiovascular Disease6.0159Citations (PDF)
48Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity
Immunometabolism, 2019, 1,
2.848Citations (PDF)
49Imaging VEGF Receptors and αvβ3 Integrins in a Mouse Hindlimb Ischemia Model of Peripheral Arterial Disease2.23Citations (PDF)
50The receptor for advanced glycation endproducts is a mediator of toxicity by IAPP and other proteotoxic aggregates: Establishing and exploiting common ground for novel amyloidosis therapies
Protein Science, 2018, 27, 1166-1180
5.925Citations (PDF)
51Highlighting Diabetes Mellitus6.0260Citations (PDF)
52Analysis of the Role of the Conserved Disulfide in Amyloid Formation by Human Islet Amyloid Polypeptide in Homogeneous and Heterogeneous Environments
Biochemistry, 2018, 57, 3065-3074
2.424Citations (PDF)
53Myeloid ATG16L1 does not affect adipose tissue inflammation or body mass in mice fed high fat diet1.67Citations (PDF)
54The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory Neurodegeneration
2018, 08,
71Citations (PDF)
55Reporting Sex and Sex Differences in Preclinical Studies6.018Citations (PDF)
56Response by Daugherty et al to Letter Regarding Article, “Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the <i>Arteriosclerosis, Thrombosis, and Vascular Biology</i> Council”6.03Citations (PDF)
57Types of tobacco consumption and the oral microbiome in the United Arab Emirates Healthy Future (UAEHFS) Pilot Study3.457Citations (PDF)
58Diaphanous 1 (DIAPH1) is Highly Expressed in the Aged Human Medial Temporal Cortex and Upregulated in Myeloid Cells During Alzheimer’s Disease
Journal of Alzheimer's Disease, 2018, 64, 995-1007
2.620Citations (PDF)
59The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals
BMC Public Health, 2018, 18,
3.146Citations (PDF)
60Amyloidogenicity, Cytotoxicity, and Receptor Activity of Bovine Amylin: Implications for Xenobiotic Transplantation and the Design of Nontoxic Amylin Variants
ACS Chemical Biology, 2018, 13, 2747-2757
3.724Citations (PDF)
61Deletion of the forminDiaph1protects from structural and functional abnormalities in the murine diabetic kidney3.326Citations (PDF)
62Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus
Medicine (United States), 2018, 97, e10955
1.23Citations (PDF)
63Patterns of tobacco use in the United Arab Emirates Healthy Future (UAEHFS) pilot study
PLoS ONE, 2018, 13, e0198119
2.343Citations (PDF)
64RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity10.680Citations (PDF)
65Small Molecule Antagonists of RAGE‐DIAPH1: Novel Therapeutic Opportunities in Metabolic and Chronic Disease
FASEB Journal, 2018, 32,
0.60Citations (PDF)
66RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis2.731Citations (PDF)
672016 ATVB Plenary Lecture6.047Citations (PDF)
68Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?
Israel Journal of Chemistry, 2017, 57, 750-761
2.015Citations (PDF)
69Ager Deletion Enhances Ischemic Muscle Inflammation, Angiogenesis, and Blood Flow Recovery in Diabetic Mice6.039Citations (PDF)
70Glycation &amp; the RAGE axis: targeting signal transduction through DIAPH1
Expert Review of Proteomics, 2017, 14, 147-156
2.031Citations (PDF)
71The AGE-RAGE axis in an Arab population: The United Arab Emirates Healthy Futures (UAEHFS) pilot study1.07Citations (PDF)
72Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE
MBio, 2017, 8,
4.468Citations (PDF)
73Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway3.766Citations (PDF)
74The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury
EBioMedicine, 2017, 26, 165-174
9.740Citations (PDF)
75[O1–14–04]: RAGE AND DIAPH‐1 REGULATE CRITICAL PHENOTYPES OF MICROGLIA IN HEALTHY AGING AND ALZHEIMER'S DISEASE0.50Citations (PDF)
76The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases2.3147Citations (PDF)
77Aldose reductase modulates acute activation of mesenchymal markers via the β-catenin pathway during cardiac ischemia-reperfusion
PLoS ONE, 2017, 12, e0188981
2.34Citations (PDF)
78Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure
PLoS ONE, 2017, 12, e0184331
2.335Citations (PDF)
79Translational Approach to Understanding RAGE pathway in Acute respiratory distress syndrome
Impact, 2016, 2016, 63-65
0.10Citations (PDF)
80Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology5.5242Citations (PDF)
81Soluble RAGE Treatment Delays Progression of Amyotrophic Lateral Sclerosis in SOD1 Mice3.438Citations (PDF)
82Soluble Receptor for Advanced Glycation End Products Improves Stromal Cell–Derived Factor-1 Activity in Model Diabetic Environments
Advances in Wound Care, 2016, 5, 527-538
5.317Citations (PDF)
83Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction3.4107Citations (PDF)
84Soluble Levels of Receptor for Advanced Glycation Endproducts (RAGE) and Progression of Atherosclerosis in Individuals Infected with Human Immunodeficiency Virus: ACTG NWCS 332
Inflammation, 2016, 39, 1354-1362
4.06Citations (PDF)
85Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor
Cell Reports, 2016, 15, 181-196
6.329Citations (PDF)
86Three-year follow-up comparing metabolic surgery versus medical weight management in patients with type 2 diabetes and BMI 30–35. The role of sRAGE biomarker as predictor of satisfactory outcomes2.529Citations (PDF)
87Cellular mechanisms and consequences of glycation in atherosclerosis and obesity4.163Citations (PDF)
88Change in the Molecular Dimension of a RAGE-Ligand Complex Triggers RAGE Signaling
Structure, 2016, 24, 1509-1522
3.860Citations (PDF)
89Mechanisms of transcription factor acetylation and consequences in hearts4.129Citations (PDF)
90Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility6.013Citations (PDF)
91The multiple faces of RAGE – opportunities for therapeutic intervention in aging and chronic disease3.796Citations (PDF)
92Emerging Targets for Therapeutic Development in Diabetes and Its Complications: The RAGE Signaling Pathway4.798Citations (PDF)
93Population-Level Prediction of Type 2 Diabetes From Claims Data and Analysis of Risk Factors
Big Data, 2015, 3, 277-287
1.6199Citations (PDF)
94Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral Sclerosis3.464Citations (PDF)
95The Growing Problem of Obesity6.016Citations (PDF)
96Soluble RAGEs — Prospects for treating &amp; tracking metabolic and inflammatory disease
Vascular Pharmacology, 2015, 72, 1-8
2.595Citations (PDF)
97Treatment effect with anti-RAGE F(ab′)2 antibody improves hind limb angiogenesis and blood flow in Type 1 diabetic mice with left femoral artery ligation
Vascular Medicine, 2015, 20, 212-218
2.416Citations (PDF)
98RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes
Diabetes, 2015, 64, 4046-4060
4.265Citations (PDF)
99Deletion of mDia1 is Protective Against Renal Damage in a Murine Model of Diabetes
FASEB Journal, 2015, 29,
0.60Citations (PDF)
100Randomized Pilot Trial of Bariatric Surgery Versus Intensive Medical Weight Management on Diabetes Remission in Type 2 Diabetic Patients Who Do NOT Meet NIH Criteria for Surgery and the Role of Soluble RAGE as a Novel Biomarker of Success
Annals of Surgery, 2014, 260, 617-624
4.6111Citations (PDF)
101Unlocking the biology of RAGE in diabetic microvascular complications8.5192Citations (PDF)
102Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation6.1149Citations (PDF)
103RAGE Regulates the Metabolic and Inflammatory Response to High-Fat Feeding in Mice
Diabetes, 2014, 63, 1948-1965
4.2198Citations (PDF)
104Imaging RAGE expression in atherosclerotic plaques in hyperlipidemic pigs
EJNMMI Research, 2014, 4,
2.612Citations (PDF)
105Recent Highlights of ATVB6.011Citations (PDF)
106Reduced expression of Munc13-1 in human and porcine diabetic peripheral nerve
Acta Histochemica, 2014, 116, 106-111
2.32Citations (PDF)
107The Receptor for Advanced Glycation End Products (RAGE) Affects T Cell Differentiation in OVA Induced Asthma
PLoS ONE, 2014, 9, e95678
2.345Citations (PDF)
108Receptor for AGE (RAGE) Expressed in Macrophages and Neurons Regulates Peripheral Nerve Repair after Injury (P1.279)
Neurology, 2014, 82,
1.00Citations (PDF)
109Imaging receptor for advanced glycation end product expression in mouse model of hind limb ischemia
EJNMMI Research, 2013, 3,
2.617Citations (PDF)
110Macrophages6.01Citations (PDF)
111Islet amyloid polypeptide toxicity and membrane interactions7.5142Citations (PDF)
112Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond4.4211Citations (PDF)
113The receptor for advanced glycation end products mediates lung endothelial activation by RBCs3.225Citations (PDF)
114Mechanisms of islet amyloidosis toxicity in type 2 diabetes
FEBS Letters, 2013, 587, 1119-1127
2.7188Citations (PDF)
115Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice3.838Citations (PDF)
116Combinatorial Library of Improved Peptide Aptamers, CLIPs to Inhibit RAGE Signal Transduction in Mammalian Cells
PLoS ONE, 2013, 8, e65180
2.325Citations (PDF)
117Microglial RAGE Accelerates Mortality and Neuronal Dysfunction in a Murine Model of Familial Amyotrophic Lateral Sclerosis (P02.173)
Neurology, 2013, 80,
1.00Citations (PDF)
118Rational design of potent domain antibody inhibitors of amyloid fibril assembly7.5104Citations (PDF)
119Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative and Signal Transduction Pathways
Circulation Research, 2012, 110, 1279-1293
13.190Citations (PDF)
120Insulin Resistance and Metabolic Syndrome6.08Citations (PDF)
121The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes
Vascular Pharmacology, 2012, 57, 160-167
2.5145Citations (PDF)
122Sensitivity of Amyloid Formation by Human Islet Amyloid Polypeptide to Mutations at Residue 20
Journal of Molecular Biology, 2012, 421, 282-295
4.184Citations (PDF)
123Glycation and Insulin Resistance6.070Citations (PDF)
124Imaging of Receptors for Advanced Glycation End Products in Experimental Myocardial Ischemia and Reperfusion Injury6.116Citations (PDF)
125Signal Transduction in Receptor for Advanced Glycation End Products (RAGE)
Journal of Biological Chemistry, 2012, 287, 5133-5144
2.2117Citations (PDF)
126Receptor for Advanced Glycation End Products (RAGE) and Implications for the Pathophysiology of Heart Failure2.977Citations (PDF)
127RAGE binds C1q and enhances C1q-mediated phagocytosis
Cellular Immunology, 2012, 274, 72-82
2.568Citations (PDF)
128RAGE Expression in Human T Cells: A Link between Environmental Factors and Adaptive Immune Responses
PLoS ONE, 2012, 7, e34698
2.396Citations (PDF)
129Alternative splicing of RAGE: roles in biology and disease5.884Citations (PDF)
130Advanced Glycation End Product Recognition by the Receptor for AGEs
Structure, 2011, 19, 722-732
3.8203Citations (PDF)
131Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes
EJNMMI Research, 2011, 1,
2.68Citations (PDF)
132Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury
Experimental Gerontology, 2011, 46, 762-767
3.720Citations (PDF)
133Human Vascular Endothelial Cells: A Model System for Studying Vascular Inflammation in Diabetes and Atherosclerosis
Current Diabetes Reports, 2011, 11, 193-202
5.1174Citations (PDF)
134Improvement in Angiogenesis and Restoration of Blood Flow in Diabetic Mice by Sanguinate TM
FASEB Journal, 2011, 25,
0.61Citations (PDF)
135Polyol pathway and RAGE: a central metabolic and signaling axis in diabetic complications2.95Citations (PDF)
136RAGE Modulates Hypoxia/Reoxygenation Injury in Adult Murine Cardiomyocytes via JNK and GSK-3β Signaling Pathways
PLoS ONE, 2010, 5, e10092
2.386Citations (PDF)
137The RAGE Axis
Circulation Research, 2010, 106, 842-853
13.1369Citations (PDF)
138Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse
Diabetes, 2010, 59, 2043-2054
4.2163Citations (PDF)
139Advanced Glycation End Product (AGE)-Receptor for AGE (RAGE) Signaling and Up-regulation of Egr-1 in Hypoxic Macrophages
Journal of Biological Chemistry, 2010, 285, 23233-23240
2.2113Citations (PDF)
140RAGE and the pathogenesis of chronic kidney disease
Nature Reviews Nephrology, 2010, 6, 352-360
32.8128Citations (PDF)
141Advanced glycation end-products: Implications for diabetic and non-diabetic nephropathies
Diabetes and Metabolism, 2010, 36, 1-10
3.5120Citations (PDF)
142RAGE, glomerulosclerosis and proteinuria: Roles in podocytes and endothelial cells8.550Citations (PDF)
143Receptor for advanced glycation endproducts mediates pro-atherogenic responses to periodontal infection in vascular endothelial cells
Atherosclerosis, 2010, 212, 451-456
1.541Citations (PDF)
144Ultrastructural Features of Retinal Capillary Basement Membrane Thickening in Diabetic Swine
Ultrastructural Pathology, 2010, 34, 35-41
1.345Citations (PDF)
145Advanced glycation endproducts: from precursors to RAGE: round and round we go
Amino Acids, 2010, 42, 1151-1161
2.3150Citations (PDF)
146Deciphering the complications of diabetes and obesity: the keystone to identification of therapeutic targets2.90Citations (PDF)
147Intra-coronary administration of soluble receptor for advanced glycation end-products attenuates cardiac remodeling with decreased myocardial transforming growth factor-β1 expression and fibrosis in minipigs with ischemia-reperfusion injury
Chinese Medical Journal, 2010, 123, 594-598
4.419Citations (PDF)
148Tempering the wrath of RAGE: An emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation
Annals of Medicine, 2009, 41, 408-422
3.8125Citations (PDF)
149Mice deficient in PKC β and apolipoprotein E display decreased atherosclerosis
FASEB Journal, 2009, 23, 1081-1091
0.674Citations (PDF)
150Alternative splicing of the murine receptor for advanced glycation end‐products (RAGE) gene
FASEB Journal, 2009, 23, 1766-1774
0.6101Citations (PDF)
151Controllable Expansion of Primary Cardiomyocytes by Reversible Immortalization
Human Gene Therapy, 2009, 20, 1687-1696
3.225Citations (PDF)
152Receptor for AGE (RAGE) and its ligands—cast into leading roles in diabetes and the inflammatory response3.7218Citations (PDF)
153Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials79.7318Citations (PDF)
154Porphyromonas gingivalis infection and prothrombotic effects in human aortic smooth muscle cells
Thrombosis Research, 2009, 123, 780-784
2.330Citations (PDF)
155Neuronal RAGE expression modulates severity of injury following transient focal cerebral ischemia1.647Citations (PDF)
156Receptor for advanced glycation end product (RAGE)-dependent modulation of early growth response-1 in hepatic ischemia/reperfusion injury
Journal of Hepatology, 2009, 50, 929-936
4.274Citations (PDF)
157RAGE: therapeutic target and biomarker of the inflammatory response—the evidence mounts
Journal of Leukocyte Biology, 2009, 86, 505-512
2.9252Citations (PDF)
158Anti-Receptor for Advanced Glycation End Products Therapies as Novel Treatment for Abdominal Aortic Aneurysm
Annals of Surgery, 2009, 250, 416-423
4.662Citations (PDF)
159The expression of the receptor for glycation endproducts (RAGE) in oral squamous cell carcinomas1.218Citations (PDF)
160Mechanisms of Disease: advanced glycation end-products and their receptor in inflammation and diabetes complications6.0391Citations (PDF)
161Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products
Circulation Research, 2008, 102, 905-913
13.1105Citations (PDF)
162Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42
Journal of Biological Chemistry, 2008, 283, 34457-34468
2.2331Citations (PDF)
163Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation1.255Citations (PDF)
164AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice3.5162Citations (PDF)
165RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model3.5130Citations (PDF)
166Identification, classification, and expression of RAGE gene splice variants
FASEB Journal, 2008, 22, 1572-1580
0.6346Citations (PDF)
167Development of Receptor for Advanced Glycation End Products–Directed Imaging of Atherosclerotic Plaque in a Murine Model of Spontaneous Atherosclerosis2.926Citations (PDF)
168Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE–/– mice10.6344Citations (PDF)
169Hypoxia-inducible Factor-1 Mediates Neuronal Expression of the Receptor for Advanced Glycation End Products following Hypoxia/Ischemia
Journal of Biological Chemistry, 2007, 282, 36330-36340
2.294Citations (PDF)
170RAGE Ligand Upregulation of VEGF Secretion in ARPE-19 Cells
2007, 48, 1355
110Citations (PDF)
171The RAGE connection to diabetes and atherosclerosis: an intertwined web of advanced glycation and inflammation
Future Lipidology, 2007, 2, 239-250
0.84Citations (PDF)
172Infection with a periodontal pathogen increases mononuclear cell adhesion to human aortic endothelial cells
Atherosclerosis, 2007, 190, 271-281
1.5102Citations (PDF)
173RAGE: Exacting a toll on the host in response to polymicrobial sepsis and Listeria monocytogenes
Critical Care, 2007, 11, 183
6.08Citations (PDF)
174Vascular endothelial sampling and analysis of gene transcripts: a new quantitative approach to monitor vascular inflammation
Journal of Applied Physiology, 2007, 103, 1873-1878
2.827Citations (PDF)
175Porphyromonas gingivalisinfection and cell death in human aortic endothelial cells
FEMS Microbiology Letters, 2007, 272, 106-113
1.955Citations (PDF)
176RAGE Activation by S100P in Colon Cancer Stimulates Growth, Migration, and Cell Signaling Pathways1.7141Citations (PDF)
177The biology of RAGE and its ligands: Uncovering mechanisms at the heart of diabetes and its complications
Current Diabetes Reports, 2007, 7, 146-153
5.153Citations (PDF)
178RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
Atherosclerosis, 2006, 185, 70-77
1.5227Citations (PDF)
179Receptor for Advanced Glycation End Products and the Cardiovascular Complications of Diabetes and Beyond: Lessons from AGEing3.521Citations (PDF)
180Glycation and RAGE: Common Links in the Pathogenesis of Microvascular and Macrovascular Complications of Diabetes
Canadian Journal of Diabetes, 2006, 30, 422-429
1.84Citations (PDF)
181Protein Kinase C β/Early Growth Response-1 Pathway2.365Citations (PDF)
182Advanced Glycation End Products
Circulation, 2006, 114, 597-605
18.02,097Citations (PDF)
183The ligand/RAGE axis: Lighting the fuse and igniting vascular stress4.718Citations (PDF)
184Induction of inflammatory bowel disease accelerates adenoma formation in Min +/− mice
Surgery, 2006, 139, 782-788
1.820Citations (PDF)
185The role of RAGE in the pathogenesis of intestinal barrier dysfunction after hemorrhagic shock3.265Citations (PDF)
186Receptor for Advanced-Glycation End Products
Circulation, 2006, 113, 1226-1234
18.0216Citations (PDF)
187The RAGE Axis and Endothelial Dysfunction: Maladaptive Roles in the Diabetic Vasculature and Beyond7.282Citations (PDF)
188Influence of ischemic injury on vein graft remodeling: Role of cyclic adenosine monophosphate second messenger pathway in enhanced vein graft preservation2.618Citations (PDF)
189At Least 2 Distinct Pathways Generating Reactive Oxygen Species Mediate Vascular Cell Adhesion Molecule-1 Induction by Advanced Glycation End Products6.0205Citations (PDF)
190Central Role of PKCβ in Neointimal Expansion Triggered by Acute Arterial Injury
Circulation Research, 2005, 96, 476-483
13.126Citations (PDF)
191RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-α and NF-κB9.3136Citations (PDF)
192Diabetic Vascular Disease: It's All the RAGE6.345Citations (PDF)
193Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells
Experimental Eye Research, 2005, 80, 567-580
2.5118Citations (PDF)
194The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study
Atherosclerosis, 2005, 182, 301-305
1.545Citations (PDF)
195Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
Glycobiology, 2005, 15, 16R-28R
2.2763Citations (PDF)
196Title is missing!3.927Citations (PDF)
197RAGE: A journey from the complications of diabetes to disorders of the nervous system – striking a fine balance between injury and repair0.76Citations (PDF)
198S100P Stimulates Cell Proliferation and Survival via Receptor for Activated Glycation End Products (RAGE)
Journal of Biological Chemistry, 2004, 279, 5059-5065
2.2241Citations (PDF)
199Protein Glycation
Circulation Research, 2004, 95, 233-238
13.1409Citations (PDF)
200Early Growth Response-1 Promotes Atherogenesis
Circulation Research, 2004, 94, 333-339
13.1148Citations (PDF)
201Antagonism of RAGE suppresses peripheral nerve regeneration
FASEB Journal, 2004, 18, 1812-1817
0.6105Citations (PDF)
202RAGE Axis6.0134Citations (PDF)
203RAGE: A Novel Target for Drug Intervention in Diabetic Vascular Disease
Pharmaceutical Research, 2004, 21, 1079-1086
3.774Citations (PDF)
204Porphyromonas gingivalisinduces its uptake by human macrophages and promotes foam cell formation in vitro
FEMS Microbiology Letters, 2004, 241, 95-101
1.981Citations (PDF)
205Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
Cardiovascular Research, 2004, 63, 582-592
5.5881Citations (PDF)
206PKCβ regulates ischemia/reperfusion injury in the lung
Journal of Clinical Investigation, 2004, 113, 1615-1623
10.652Citations (PDF)
207Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
Journal of Clinical Investigation, 2004, 113, 1641-1650
10.6446Citations (PDF)
208PKCβ regulates ischemia/reperfusion injury in the lung
Journal of Clinical Investigation, 2004, 113, 1615-1623
10.66Citations (PDF)
209RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
Nature Medicine, 2003, 9, 907-913
33.01,410Citations (PDF)
210RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy
American Journal of Pathology, 2003, 162, 1123-1137
3.4574Citations (PDF)
211Central role of RAGE-dependent neointimal expansion in arterial restenosis10.6291Citations (PDF)
212Glycation, Inflammation, and RAGE
Circulation Research, 2003, 93, 1159-1169
13.1501Citations (PDF)
213Oral Infection With a Periodontal Pathogen Accelerates Early Atherosclerosis in Apolipoprotein E–Null Mice6.0352Citations (PDF)
214Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: A new insight into selective nitrergic neuropathy in diabetes
Diabetologia, 2003, 47, 331-339
7.5103Citations (PDF)
215Central role of RAGE-dependent neointimal expansion in arterial restenosis10.6196Citations (PDF)
216Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes11.6263Citations (PDF)
217Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings
Advanced Drug Delivery Reviews, 2002, 54, 1615-1625
15.4261Citations (PDF)
218Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: Insights into the pathogenesis of macrovascular complications in diabetes4.7172Citations (PDF)
219RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease5.5286Citations (PDF)
220RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response
Genes and Immunity, 2002, 3, 123-135
3.8356Citations (PDF)
221Receptor for Advanced Glycation End Products on Human Synovial Fibroblasts0.444Citations (PDF)
222Receptor for Advanced Glycation End Products, Inflammation, and Accelerated Periodontal Disease in Diabetes: Mechanisms and Insights Into Therapeutic Modalities
2001, 6, 113-118
147Citations (PDF)
223Involvement of Microglial Receptor for Advanced Glycation Endproducts (RAGE) in Alzheimer's Disease: Identification of a Cellular Activation Mechanism
Experimental Neurology, 2001, 171, 29-45
4.0413Citations (PDF)
224Blockade of Receptor for Advanced Glycation End-Products Restores Effective Wound Healing in Diabetic Mice
American Journal of Pathology, 2001, 159, 513-525
3.4414Citations (PDF)
225Key signaling pathways regulate the biological activities and accumulation of amyloid-β
Neurobiology of Aging, 2001, 22, 967-973
3.415Citations (PDF)
226Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease5.866Citations (PDF)
227Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE3.0968Citations (PDF)
228β2-Microglobulin modified with advanced glycation end products delays monocyte apoptosis
Kidney International, 2001, 59, 990-1002
5.372Citations (PDF)
229Colonoscopy in Mice2.340Citations (PDF)
230Hyperglycemia, glycoxidation and receptor for advanced glycation endproducts: potential mechanisms underlying diabetic complications, including diabetes-associated periodontitis
Periodontology 2000, 2000, 23, 50-62
14.8139Citations (PDF)
231Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases
Nature, 2000, 405, 354-360
37.91,174Citations (PDF)
232Atherosclerosis and diabetes: The rage connection4.7177Citations (PDF)
233β-Amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-14.2211Citations (PDF)
234Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice
Journal of Clinical Investigation, 2000, 105, 1117-1124
10.6327Citations (PDF)
235RAGE: A Multiligand Receptor Contributing to the Cellular Response in Diabetic Vasculopathy and Inflammation2.5125Citations (PDF)
236The biology of the receptor for advanced glycation end products and its ligands3.6617Citations (PDF)
237Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid β-peptide4.156Citations (PDF)
238RAGE: A New Target for the Prevention and Treatment of the Vascular and Inflammatory Complications of Diabetes8.5161Citations (PDF)
239Expression of Advanced Glycation End Products and Their Cellular Receptor RAGE in Diabetic Nephropathy and Nondiabetic Renal Disease0.4434Citations (PDF)
240N ε-(Carboxymethyl)Lysine Adducts of Proteins Are Ligands for Receptor for Advanced Glycation End Products That Activate Cell Signaling Pathways and Modulate Gene Expression
Journal of Biological Chemistry, 1999, 274, 31740-31749
2.2833Citations (PDF)
241Soluble cellular adhesion molecules in proliferative vitreoretinopathy and proliferative diabetic retinopathy
Current Eye Research, 1999, 19, 219-227
2.144Citations (PDF)
242Emerging therapeutic targets in diabetic vascular disease0.80Citations (PDF)
243Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats2.035Citations (PDF)
244RAGE Mediates a Novel Proinflammatory Axis
Cell, 1999, 97, 889-901
33.61,827Citations (PDF)
245Cellular Cofactors for Amyloid β-Peptide-Induced Cell Stress
American Journal of Pathology, 1999, 155, 1403-1411
3.437Citations (PDF)
246Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
Nature Medicine, 1998, 4, 1025-1031
33.01,104Citations (PDF)
247β2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts
Kidney International, 1998, 53, 1365-1373
5.387Citations (PDF)
248Vasculopathy and insulin resistance in the JCR:LA-cp rat
Atherosclerosis, 1998, 138, 135-146
1.556Citations (PDF)
249Enhanced Interaction of Advanced Glycation End Products With Their Cellular Receptor RAGE: Implications for the Pathogenesis of Accelerated Periodontal Disease in Diabetes
Annals of Periodontology, 1998, 3, 13-19
6.8100Citations (PDF)
250Sp1-binding Elements in the Promoter of RAGE Are Essential for Amphoterin-mediated Gene Expression in Cultured Neuroblastoma Cells
Journal of Biological Chemistry, 1998, 273, 30870-30878
2.274Citations (PDF)
251Vitamin E ameliorates enhanced renal lipid peroxidation and accumulation of F2-isoprostanes in aging kidneys2.441Citations (PDF)
252A murine model of accelerated periodontal disease in diabetes3.481Citations (PDF)
253Characterization and Functional Analysis of the Promoter of RAGE, the Receptor for Advanced Glycation End Products
Journal of Biological Chemistry, 1997, 272, 16498-16506
2.2462Citations (PDF)
254Pathogenesis of diabetic nephropathy: a radical approach0.868Citations (PDF)
255Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress
Journal of Biological Chemistry, 1997, 272, 17810-17814
2.2737Citations (PDF)
256Recombinant Advanced Glycation End Product Receptor Pharmacokinetics in Normal and Diabetic Rats
Molecular Pharmacology, 1997, 52, 54-62
2.682Citations (PDF)
257Endothelial-monocyte activating polypeptide ii, a novel anti-tumor cytokine that suppresses primary and metastatic tumor growth, and induces apoptosis in growing endothelial cells.6.60Citations (PDF)
258The receptor for advanced glycation products (rage): Implications for the pathogenesis of diabetic complications.6.60Citations (PDF)
259Receptors for advanced glycation end-products (AGE)—expression by endothelial cells in non-diabetic uraemic patients0.80Citations (PDF)
260Elevated plasma levels of vascular cell adhesion molecule‐1 (VCAM‐1) in diabetic patients with microalbuminuria: a marker of vascular dysfunction and progressive vascular disease2.7104Citations (PDF)
261Advanced glycation endproducts (AGEs) induce oxidant stress in the gingiva: a potential mechanism underlying accelerated periodontal disease associated with diabetes3.4261Citations (PDF)
262RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
Nature, 1996, 382, 685-691
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263Receptors for advanced glycation end-products (AGE)--expression by endothelial cells in non-diabetic uraemic patients0.842Citations (PDF)
264The receptor for advanced glycation end-products has a central role in mediating the effects of advanced glycation end-products on the development of vascular disease in diabetes mellitus0.875Citations (PDF)
265Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats.10.6495Citations (PDF)
266The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis.10.6275Citations (PDF)
267The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin
Journal of Biological Chemistry, 1995, 270, 25752-25761
2.21,090Citations (PDF)
268Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.10.6829Citations (PDF)
269Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating AGE proteins.7.5315Citations (PDF)
270Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications.7.5337Citations (PDF)
271Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress.7.5585Citations (PDF)
272Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end products.10.6265Citations (PDF)
273Resolution of fluorescence intensity decays of the two tryptophan residues in glutamine-binding protein from Escherichia coli using single tryptophan mutants
Biophysical Journal, 1991, 60, 650-659
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274Viral persistence during the developmental phase of Coxsackievirus B1-induced murine polymyositis
Journal of Virology, 1991, 65, 6654-6660
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275Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
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276ATVB Journal Awards at Vascular Discovery6.00Citations (PDF)