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130 peer-reviewed articles • 14,878 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist
Cell Reports, 2025, 44, 115111
4.46Citations (PDF)
2Rabies vaccination induces a CD4+ TEM and CD4+CD8+ TEMRA TH1 phenotype in dogs
PLoS ONE, 2025, 20, e0323823
1.55Citations (PDF)
3Antigen-specific CD4+ T cells promote monocyte recruitment and differentiation into glycolytic lung macrophages to control Mycobacterium tuberculosis
PLoS Pathogens, 2025, 21, e1013208
2.911Citations (PDF)
4Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells1.66Citations (PDF)
5Toward a general model of CD4+ T cell subset specification and memory cell formation
Immunity, 2023, 56, 475-484
16.661Citations (PDF)
6Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA–vaccinated patients with inflammatory bowel disease
JCI Insight, 2022, 7,
3.76Citations (PDF)
7Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction
Nature, 2022, 607, 762-768
31.3102Citations (PDF)
8Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA
Clinical Biochemistry, 2021, 90, 15-22
1.321Citations (PDF)
9Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
Immunity, 2021, 54, 687-701.e4
16.667Citations (PDF)
10CD4+ Memory T-Cell Formation during Type 1 Immune Responses4.624Citations (PDF)
11MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells
Nature Biotechnology, 2021, 39, 943-948
20.237Citations (PDF)
12Intranasal Nanoparticle Vaccination Elicits a Persistent, Polyfunctional CD4 T Cell Response in the Murine Lung Specific for a Highly Conserved Influenza Virus Antigen That Is Sufficient To Mediate Protection from Influenza Virus Challenge2.419Citations (PDF)
13High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines
Cell Reports, 2021, 37, 109823
4.4112Citations (PDF)
14Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection
PLoS Pathogens, 2021, 17, e1009897
2.975Citations (PDF)
15Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers5.962Citations (PDF)
16Antigen-Specific CD4+ T Cells Exhibit Distinct Kinetic and Phenotypic Patterns During Primary and Secondary Responses to Infection3.311Citations (PDF)
17A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation
Immunity, 2019, 51, 465-478.e6
16.641Citations (PDF)
18BCL6 corepressor contributes to Th17 cell formation by inhibiting Th17 fate suppressors
Journal of Experimental Medicine, 2019, 216, 1450-1464
5.928Citations (PDF)
19Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors5.328Citations (PDF)
20Regulatory CD4 + T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B
Circulation, 2018, 138, 1130-1143
13.1192Citations (PDF)
21Do Memory B Cells Form Secondary Germinal Centers?4.636Citations (PDF)
22Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells
Immunity, 2018, 49, 1090-1102.e7
16.690Citations (PDF)
23Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires2.712Citations (PDF)
24Naive B Cells with High-Avidity Germline-Encoded Antigen Receptors Produce Persistent IgM+ and Transient IgG+ Memory B Cells
Immunity, 2018, 48, 1135-1143.e4
16.676Citations (PDF)
25Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen
Immunity, 2017, 47, 107-117.e8
16.671Citations (PDF)
26Identification of MHC-Bound Peptides from Dendritic Cells Infected with Salmonella enterica Strain SL1344: Implications for a Nontyphoidal Salmonella Vaccine
Journal of Proteome Research, 2017, 16, 298-306
2.331Citations (PDF)
27Increased Effector Memory Insulin-Specific CD4+ T Cells Correlate With Insulin Autoantibodies in Patients With Recent-Onset Type 1 Diabetes
Diabetes, 2017, 66, 3051-3060
3.543Citations (PDF)
28Normalizing the environment recapitulates adult human immune traits in laboratory mice
Nature, 2016, 532, 512-516
31.31,090Citations (PDF)
29Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment11.032Citations (PDF)
30CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
Nature Immunology, 2016, 17, 304-314
14.4245Citations (PDF)
31Tolerance is established in polyclonal CD4+ T cells by distinct mechanisms, according to self-peptide expression patterns
Nature Immunology, 2016, 17, 187-195
14.4214Citations (PDF)
32The Transcription Factor KLF2 Restrains CD4 + T Follicular Helper Cell Differentiation
Immunity, 2015, 42, 252-264
16.6194Citations (PDF)
33T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity
Immunity, 2015, 42, 95-107
16.6163Citations (PDF)
34Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection
PLoS Pathogens, 2015, 11, e1004701
2.9205Citations (PDF)
35Calnexin Induces Expansion of Antigen-Specific CD4+ T Cells that Confer Immunity to Fungal Ascomycetes via Conserved Epitopes
Cell Host and Microbe, 2015, 17, 452-465
12.272Citations (PDF)
36Generation of Th17 cells in response to intranasal infection requires TGF-β1 from dendritic cells and IL-6 from CD301b + dendritic cells5.372Citations (PDF)
37TCR ITAM multiplicity is required for the generation of follicular helper T-cells11.033Citations (PDF)
38The Neonatal CD4+ T Cell Response to a Single Epitope Varies in Genetically Identical Mice
Journal of Immunology, 2015, 195, 2115-2121
0.88Citations (PDF)
39CD4+T Cells: Guardians of the Phagosome10.7102Citations (PDF)
40Focused specificity of intestinal TH17 cells towards commensal bacterial antigens
Nature, 2014, 510, 152-156
31.3525Citations (PDF)
41TCR signal quantity and quality in CD4+ T cell differentiation
Trends in Immunology, 2014, 35, 591-596
8.4151Citations (PDF)
42Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse1.031Citations (PDF)
43Tracking antigen‐specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice2.433Citations (PDF)
44Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
Cell, 2013, 153, 785-796
23.8477Citations (PDF)
45PD-1, but Not PD-L1, Expressed by Islet-Reactive CD4+ T Cells Suppresses Infiltration of the Pancreas During Type 1 Diabetes
Diabetes, 2013, 62, 2859-2869
3.576Citations (PDF)
46Pillars Article: Visualization of Peptide-Specific T Cell Immunity and Peripheral Tolerance Induction In Vivo. <i>Immunity</i>. 1994. 1: 327-339
Journal of Immunology, 2013, 191, 5327-5339
0.81Citations (PDF)
47Temporal Expression of Bacterial Proteins Instructs Host CD4 T Cell Expansion and Th17 Development
PLoS Pathogens, 2012, 8, e1002499
2.979Citations (PDF)
48The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude
Journal of Immunology, 2012, 188, 4135-4140
0.8319Citations (PDF)
49Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection5.399Citations (PDF)
50A germinal center–independent pathway generates unswitched memory B cells early in the primary response5.9377Citations (PDF)
51Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen
Journal of Experimental Medicine, 2012, 209, 2065-2077
5.9174Citations (PDF)
52Heterogeneity in the differentiation and function of memory B cells
Trends in Immunology, 2012, 33, 590-597
8.467Citations (PDF)
53The Transcription Factors Thpok and LRF Are Necessary and Partly Redundant for T Helper Cell Differentiation
Immunity, 2012, 37, 622-633
16.645Citations (PDF)
54Quantitative impact of thymic selection on Foxp3 + and Foxp3 − subsets of self-peptide/MHC class II-specific CD4 + T cells5.3114Citations (PDF)
55Opposing Signals from the Bcl6 Transcription Factor and the Interleukin-2 Receptor Generate T Helper 1 Central and Effector Memory Cells
Immunity, 2011, 35, 583-595
16.6418Citations (PDF)
56Origins of CD4+ effector and central memory T cells
Nature Immunology, 2011, 12, 467-471
14.4372Citations (PDF)
57CD4+ memory T cell survival3.741Citations (PDF)
58Robust Antigen Specific Th17 T Cell Response to Group A Streptococcus Is Dependent on IL-6 and Intranasal Route of Infection
PLoS Pathogens, 2011, 7, e1002252
2.9103Citations (PDF)
59Distinct functions of antigen-specific CD4 T cells during murineMycobacterium tuberculosisinfection5.3182Citations (PDF)
60A Protease-Dependent Mechanism for Initiating T-Dependent B Cell Responses to Large Particulate Antigens
Journal of Immunology, 2010, 184, 3609-3617
0.847Citations (PDF)
61On the Composition of the Preimmune Repertoire of T Cells Specific for Peptide–Major Histocompatibility Complex Ligands
Annual Review of Immunology, 2010, 28, 275-294
22.4235Citations (PDF)
62Positive selection optimizes the number and function of MHCII-restricted CD4+T cell clones in the naive polyclonal repertoire5.349Citations (PDF)
63Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin
Immunity, 2009, 30, 277-288
16.6154Citations (PDF)
64Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells
Nature Immunology, 2009, 11, 83-89
14.4265Citations (PDF)
65Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319
Journal of Immunology, 2009, 183, 4150-4167
0.81Citations (PDF)
66Imaging the immune system
Immunological Reviews, 2008, 221, 5-6
6.15Citations (PDF)
67Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire
Immunity, 2008, 28, 112-121
16.6376Citations (PDF)
68Phenotypic similarities of anergic and regulatory T cells
FASEB Journal, 2008, 22,
2.30Citations (PDF)
69CD28 enhances in vivo clonal expansion by CD4+ T cells without increasing sensitivity to antigen
FASEB Journal, 2008, 22,
2.30Citations (PDF)
70Surface antigens are rapidly separated from bacterium‐sized microspheres in the subcapsular sinus and acquired by antigen‐specific follicular B cells
FASEB Journal, 2008, 22,
2.30Citations (PDF)
71The naïve CD8+ T cell pool contains a variable frequency of memory phenotype T cells bearing the signature of homeostatic expansion
FASEB Journal, 2008, 22, 355-355
2.33Citations (PDF)
72CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection5.345Citations (PDF)
73The Humoral Immune Response Is Initiated in Lymph Nodes by B Cells that Acquire Soluble Antigen Directly in the Follicles
Immunity, 2007, 26, 491-502
16.6365Citations (PDF)
74Naive CD4+ T Cell Frequency Varies for Different Epitopes and Predicts Repertoire Diversity and Response Magnitude
Immunity, 2007, 27, 203-213
16.6941Citations (PDF)
75Delayed gratification: A program of intimal hyperplasia progresses even as graft antigen-specific CD4+ T cells subside0.90Citations (PDF)
76CD154+ Graft Antigen-Specific CD4+ T Cells are Sufficient for Chronic Rejection of Minor Antigen Incompatible Heart Grafts3.610Citations (PDF)
77CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central–memory cells
Journal of Experimental Medicine, 2006, 203, 1045-1054
5.9148Citations (PDF)
78In vivo antigen presentation3.781Citations (PDF)
79Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection
European Journal of Immunology, 2004, 34, 2843-2853
2.445Citations (PDF)
80Visualizing the First 50 Hr of the Primary Immune Response to a Soluble Antigen
Immunity, 2004, 21, 341-347
16.6183Citations (PDF)
81Development of a Novel Transgenic Mouse for the Study of Interactions Between CD4 and CD8 T Cells During Graft Rejection3.6192Citations (PDF)
82Whole-body analysis of T cell responses3.721Citations (PDF)
83Antigen presentation to naive CD4 T cells in the lymph node
Nature Immunology, 2003, 4, 733-739
14.4424Citations (PDF)
84Distinct Dendritic Cell Populations Sequentially Present Antigen to CD4 T Cells and Stimulate Different Aspects of Cell-Mediated Immunity
Immunity, 2003, 19, 47-57
16.6692Citations (PDF)
85Preferential Accumulation of Antigen-specific Effector CD4 T Cells at an Antigen Injection Site Involves CD62E-dependent Migration but Not Local Proliferation5.9139Citations (PDF)
86Visualization of the Genesis and Fate of Isotype-switched B Cells during a Primary Immune Response
Journal of Experimental Medicine, 2003, 197, 1677-1687
5.9136Citations (PDF)
87Tracking Salmonella-Specific CD4 T Cells In Vivo Reveals a Local Mucosal Response to a Disseminated Infection
Immunity, 2002, 16, 365-377
16.6220Citations (PDF)
88INVIVOACTIVATION OFANTIGEN-SPECIFICCD4 T CELLS22.4486Citations (PDF)
89Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions2.4129Citations (PDF)
90Visualizing the generation of memory CD4 T cells in the whole body
Nature, 2001, 410, 101-105
31.3993Citations (PDF)
91Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivo5.375Citations (PDF)
92Antibody Is Required for Protection against Virulent but Not Attenuated Salmonella enterica Serovar Typhimurium
Infection and Immunity, 2000, 68, 3344-3348
2.0188Citations (PDF)
93Clonal Expansion of Antigen-Specific CD4 T Cells following Infection with Salmonella typhimurium Is Similar in Susceptible ( Ity s ) and Resistant ( Ity r ) BALB/c Mice
Infection and Immunity, 1999, 67, 2025-2029
2.025Citations (PDF)
94Self-Reactive B Lymphocytes Overexpressing Bcl-xL Escape Negative Selection and Are Tolerized by Clonal Anergy and Receptor Editing
Immunity, 1998, 9, 35-45
16.6120Citations (PDF)
95A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism5.9208Citations (PDF)
96Prevention of Peripheral Tolerance by a Dendritic Cell Growth Factor: Flt3 Ligand as an Adjuvant
Journal of Experimental Medicine, 1998, 188, 2075-2082
5.9104Citations (PDF)
97Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection5.3213Citations (PDF)
98In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells
Journal of Experimental Medicine, 1997, 185, 2133-2141
5.9525Citations (PDF)
99MURINE LYMPHOTACTIN: GENE STRUCTURE, POST-TRANSLATIONAL MODIFICATION AND INHIBITION OF EXPRESSION BY CD28 COSTIMULATION
Cytokine, 1997, 9, 375-382
2.018Citations (PDF)
100Use of adoptive transfer of T-cell antigen-receptor-transgenic T cells for the study of T-cell activation in vivo
Immunological Reviews, 1997, 156, 67-78
6.1195Citations (PDF)
101Autoimmunity: When self-tolerance breaks down
Current Biology, 1997, 7, R255-R257
2.513Citations (PDF)
102Studying Immunological Tolerance by Physically Monitoring Antigen-specific T Cells in Vivoa2.67Citations (PDF)
103The anatomy of T-cell activation and tolerance.5.3215Citations (PDF)
104Molecular mechanisms underlying functional T-cell unresponsiveness3.7378Citations (PDF)
105Accumulation of Sequence-specific RNA-binding Proteins in the Cytosol of Activated T Cells Undergoing RNA Degradation and Apoptosis
Journal of Biological Chemistry, 1995, 270, 26593-26601
1.327Citations (PDF)
106Surface proteins involved in T cell costimulation
Journal of Leukocyte Biology, 1994, 55, 805-815
1.795Citations (PDF)
107Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
Immunity, 1994, 1, 327-339
16.6908Citations (PDF)
108Minireview The role of anergy in peripheral T cell unresponsiveness
Life Sciences, 1994, 55, 1767-1780
3.829Citations (PDF)
109The ups and downs of T cell costimulation
Immunity, 1994, 1, 443-446
16.6240Citations (PDF)
110The murine immune response to the male-specific antigen mouse testicular cytochromec
European Journal of Immunology, 1993, 23, 1992-1998
2.40Citations (PDF)
111Molecules involved in T-cell costimulation3.7224Citations (PDF)
112Accessory cell-derived signals required for T cell activation
Immunologic Research, 1993, 12, 48-64
1.639Citations (PDF)
113A single amino acid substitution in a cytochrome c T cell stimulatory peptide changes the MHC restriction element from one isotype (I-Ak) to another (I-Ek)
Molecular Immunology, 1993, 30, 569-575
2.02Citations (PDF)
114Self-reactive T cells are present in the peripheral lymphoid tissues of cyclosporin A-treated mice
International Immunology, 1992, 4, 1341-1349
2.024Citations (PDF)
115Co-Stimulatory Functions of Antigen-Presenting Cells1.814Citations (PDF)
116The role of cell division in the induction of clonal anergy
Trends in Immunology, 1992, 13, 69-73
7.1199Citations (PDF)
117nef-naf nexus?
Current Biology, 1992, 2, 130-132
2.56Citations (PDF)
118Accessory Cell-Derived Costimulatory Signals Regulate T Cell Proliferation2.69Citations (PDF)
119A monoclonal antibody specific for a cytochromec T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells2.433Citations (PDF)
120Cell and receptor requirements for streptococcal pyrogenic exotoxin T-cell mitogenicity
Infection and Immunity, 1991, 59, 1210-1214
2.044Citations (PDF)
121Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy
Annual Review of Immunology, 1989, 7, 445-480
22.41,490Citations (PDF)
122Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.5.91,118Citations (PDF)
123In Vitro and In Vivo Correlates of Hybrid Tumor Resistance23.40Citations (PDF)
124Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones.5.3293Citations (PDF)
125T-Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State
Immunological Reviews, 1987, 95, 113-135
6.1188Citations (PDF)
126Mechanisms of genetic control of immune responses
Immunogenetics, 1986, 23, 292-301
1.14Citations (PDF)
127In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity
Cellular Immunology, 1985, 92, 414-426
1.564Citations (PDF)
128Immunoregulatory Pathways in Adult Responder Mice.1.29Citations (PDF)
129Foreign epitope–specific regulatory T cells respond robustly to vaccination and limit Th1 differentiation by conventional T cells specific for the same epitope
Journal of Immunology, 0, 214, 3345-3356
0.80Citations (PDF)
130Gut microbial composition modulates endogenous food-specific CD4+ T cells in food allergy0.80Citations (PDF)