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745 papers • 123,259 citations • Sorted by year • Download PDF (PDF by citations)
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1Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation4.41Citations (PDF)
2Endothelial dysfunction in the aging kidney3.41Citations (PDF)
3Fatty acid oxidation fuels natural killer cell responses against infection and cancer7.710Citations (PDF)
4FOXF1 promotes tumor vessel normalization and prevents lung cancer progression through FZD4
EMBO Molecular Medicine, 2024, 16, 1063-1090
7.22Citations (PDF)
5Functional synergy of a human-specific and an ape-specific metabolic regulator in human neocortex development14.17Citations (PDF)
6Weak neuronal glycolysis sustains cognition and organismal fitness
Nature Metabolism, 2024, 6, 1253-1267
11.99Citations (PDF)
7The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells4.51Citations (PDF)
8Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance
Nature Cancer, 2024, 5, 1206-1226
13.914Citations (PDF)
9Single-cell atlas of the human brain vasculature across development, adulthood and disease
Nature, 2024, 632, 603-613
40.121Citations (PDF)
10GAS6 and AXL Promote Insulin Resistance by Rewiring Insulin Signaling and Increasing Insulin Receptor Trafficking to Endosomes
Diabetes, 2024, 73, 1648-1661
0.50Citations (PDF)
11Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation14.11Citations (PDF)
12Immunomodulation by endothelial cells: prospects for cancer therapy
Trends in Cancer, 2024, 10, 1072-1091
14.00Citations (PDF)
13Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice14.10Citations (PDF)
14Deciphering endothelial heterogeneity in health and disease at single-cell resolution: progress and perspectives
Cardiovascular Research, 2023, 119, 6-27
5.629Citations (PDF)
15The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution
Cardiovascular Research, 2023, 119, 520-535
5.621Citations (PDF)
16Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation14.117Citations (PDF)
17Shaping the brain vasculature in development and disease in the single-cell era
Nature Reviews Neuroscience, 2023, 24, 271-298
10.052Citations (PDF)
18Prioritization and functional validation of target genes from single-cell transcriptomics studies4.52Citations (PDF)
19Understanding tumour endothelial cell heterogeneity and function from single-cell omics
Nature Reviews Cancer, 2023, 23, 544-564
24.258Citations (PDF)
20Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition
Nature Metabolism, 2023, 5, 1290-1302
11.952Citations (PDF)
21VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway26.319Citations (PDF)
22Targeting hypoxia-inducible factors: therapeutic opportunities and challenges39.346Citations (PDF)
23Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
Cardiovascular Research, 2022, 118, 1232-1246
5.616Citations (PDF)
24Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension
Cardiovascular Research, 2022, 118, 2519-2534
5.661Citations (PDF)
25Identification of vascular cues contributing to cancer cell stemness and function
Angiogenesis, 2022, 25, 355-371
7.412Citations (PDF)
26De novo serine synthesis regulates chondrocyte proliferation during bone development and repair
Bone Research, 2022, 10,
14.125Citations (PDF)
27Immunomodulation by endothelial cells — partnering up with the immune system?
Nature Reviews Immunology, 2022, 22, 576-588
17.9210Citations (PDF)
28Mitochondrial respiration supports autophagy to provide stress resistance during quiescence
Autophagy, 2022, 18, 2409-2426
13.820Citations (PDF)
29Author response: Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
2022, ,
0Citations (PDF)
30A Role for the Vascular Endothelium in Post–Acute COVID-19?
Circulation, 2022, 145, 1503-1505
19.416Citations (PDF)
31Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis14.126Citations (PDF)
32PHGDH heterogeneity potentiates cancer cell dissemination and metastasis
Nature, 2022, 605, 747-753
40.1115Citations (PDF)
33A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth
Nature Metabolism, 2022, 4, 672-682
11.940Citations (PDF)
34Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level14.131Citations (PDF)
35Endothelial cell heterogeneity and plasticity in health and disease—new insights from single-cell studies
2022, , 17-28
1Citations (PDF)
36A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma
Clinical Cancer Research, 2022, 28, 3950-3957
6.48Citations (PDF)
37Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers14.123Citations (PDF)
38Analyzing cell-type-specific dynamics of metabolism in kidney repair
Nature Metabolism, 2022, 4, 1109-1118
11.979Citations (PDF)
39Metabolic Reprogramming in Tumor Endothelial Cells4.528Citations (PDF)
40Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast14.165Citations (PDF)
41HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury
JCI Insight, 2022, 7,
5.512Citations (PDF)
42Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice5.144Citations (PDF)
43Transcriptomic analysis of CFTR-impaired endothelial cells reveals a pro-inflammatory phenotype
European Respiratory Journal, 2021, 57, 2000261
7.718Citations (PDF)
44Successful double-lung transplantation from a donor previously infected with SARS-CoV-222.141Citations (PDF)
45Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
Cell Metabolism, 2021, 33, 411-423.e4
26.3109Citations (PDF)
46Phenotypic diversity and metabolic specialization of renal endothelial cells
Nature Reviews Nephrology, 2021, 17, 441-464
13.673Citations (PDF)
47Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance9.138Citations (PDF)
48Whole-Body Prolyl Hydroxylase Domain (PHD) 3 Deficiency Increased Plasma Lipids and Hematocrit Without Impacting Plaque Size in Low-Density Lipoprotein Receptor Knockout Mice3.73Citations (PDF)
49Endothelial metabolism going single
Nature Metabolism, 2021, 3, 593-594
11.92Citations (PDF)
50Endothelial cell plasticity at the single-cell level
Angiogenesis, 2021, 24, 311-326
7.454Citations (PDF)
51Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis
Endocrinology, 2021, 162,
2.722Citations (PDF)
52High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity
Cell Reports, 2021, 35, 109212
6.4106Citations (PDF)
53Protocols for endothelial cell isolation from mouse tissues: small intestine, colon, heart, and liver
STAR Protocols, 2021, 2, 100489
1.113Citations (PDF)
54Tumor vessel co-option probed by single-cell analysis
Cell Reports, 2021, 35, 109253
6.456Citations (PDF)
55Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis3.78Citations (PDF)
56Endothelial CFTR dysfunction and its involvement in the pathogenesis of pulmonary arterial hypertension
European Respiratory Journal, 2021, 58, 2101645
7.72Citations (PDF)
57Persistence of SARS-CoV-2 RNA in lung tissue after mild COVID-1922.139Citations (PDF)
58Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in the entire postnatal and adult mouse brain
Nature Protocols, 2021, 16, 4564-4610
14.633Citations (PDF)
59Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis
STAR Protocols, 2021, 2, 100523
1.112Citations (PDF)
60Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
Cell Metabolism, 2021, 33, 1763-1776.e5
26.336Citations (PDF)
61Comparative meta-analysis of cystic fibrosis cell models suggests partial endothelial-to-mesenchymal transition
Journal of Cystic Fibrosis, 2021, 20, 876-880
0.85Citations (PDF)
62Cardiac Microvascular Endothelial Cells in Pressure Overload–Induced Heart Disease4.822Citations (PDF)
63Tissue factor cytoplasmic domain exacerbates post-infarct left ventricular remodeling via orchestrating cardiac inflammation and angiogenesis
Theranostics, 2021, 11, 9243-9261
11.415Citations (PDF)
64The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors
Cancers, 2021, 13, 5090
4.016Citations (PDF)
65Shear Stress Regulation of Endothelial Glycocalyx Structure Is Determined by Glucobiosynthesis6.281Citations (PDF)
66Homeostasis and transitional activation of regulatory T cells require c-Myc
Science Advances, 2020, 6,
11.360Citations (PDF)
67Metabolic Signatures of Distinct Endothelial Phenotypes11.853Citations (PDF)
68Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility
Cell Reports, 2020, 32, 107880
6.46Citations (PDF)
69c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis
Nature Metabolism, 2020, 2, 1350-1367
11.916Citations (PDF)
70DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance
Genome Biology, 2020, 21,
8.442Citations (PDF)
71Macrophage-derived glutamine boosts satellite cells and muscle regeneration
Nature, 2020, 587, 626-631
40.1143Citations (PDF)
72BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization
Nucleic Acids Research, 2020, 48, W385-W394
16.245Citations (PDF)
73Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
Cell Metabolism, 2020, 31, 1136-1153.e7
26.3281Citations (PDF)
74Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity
Circulation Research, 2020, 127, 466-482
12.8124Citations (PDF)
75Glutamine Metabolism Controls Chondrocyte Identity and Function
Developmental Cell, 2020, 53, 530-544.e8
7.873Citations (PDF)
76COVID-19: the vasculature unleashed
Nature Reviews Immunology, 2020, 20, 389-391
17.9794Citations (PDF)
77Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies3.610Citations (PDF)
78Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines14.182Citations (PDF)
79Basic and Therapeutic Aspects of Angiogenesis Updated
Circulation Research, 2020, 127, 310-329
12.8321Citations (PDF)
80Lipid availability determines fate of skeletal progenitor cells via SOX9
Nature, 2020, 579, 111-117
40.1159Citations (PDF)
81Single-Cell Transcriptome Atlas of Murine Endothelial Cells
Cell, 2020, 180, 764-779.e20
35.1776Citations (PDF)
82An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
Cancer Cell, 2020, 37, 21-36.e13
33.4271Citations (PDF)
83PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase14.1171Citations (PDF)
84Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis7.242Citations (PDF)
85Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis
Cell Metabolism, 2020, 31, 862-877.e14
26.3194Citations (PDF)
86Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation0.4131Citations (PDF)
87Matrix deformations around angiogenic sprouts correlate to sprout dynamics and suggest pulling activity
Angiogenesis, 2020, 23, 315-324
7.438Citations (PDF)
88Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation
Cell Metabolism, 2019, 30, 824-832.e3
26.386Citations (PDF)
89Functional reprogramming of regulatory T cells in the absence of Foxp3
Nature Immunology, 2019, 20, 1208-1219
13.1108Citations (PDF)
90Myeloid Phd2 Knockdown Drives Macrophage Apoptosis And Paracrine Fibroblast/Smooth Muscle Cell Collagen Secretion Leading To Atherosclerotic Plaque Fibrosis
Atherosclerosis, 2019, 287, e10
1.20Citations (PDF)
91Adult Pgf−/− mice behaviour and neuroanatomy are altered by neonatal treatment with recombinant placental growth factor3.710Citations (PDF)
92Role and therapeutic potential of dietary ketone bodies in lymph vessel growth
Nature Metabolism, 2019, 1, 666-675
11.951Citations (PDF)
93PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production3.741Citations (PDF)
94P021 CFTR loss of function leads to increased ROS and endothelial dysfunction
Journal of Cystic Fibrosis, 2019, 18, S62-S63
0.80Citations (PDF)
95Partial Inhibition Of The Key Glycolytic Enzyme Pfkfb3 In Myeloid Cells Impacts Whole-Body Immune Cell And Liver Metabolism, But Not Atherogenesis.
Atherosclerosis, 2019, 287, e19-e20
1.21Citations (PDF)
96Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation
Stem Cell Reports, 2019, 13, 803-816
4.717Citations (PDF)
97Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium0.453Citations (PDF)
98Hallmarks of Endothelial Cell Metabolism in Health and Disease
Cell Metabolism, 2019, 30, 414-433
26.3296Citations (PDF)
99Differentiation but not ALS mutations in FUS rewires motor neuron metabolism14.138Citations (PDF)
100Analysis of Endothelial Fatty Acid Metabolism Using Tracer Metabolomics0.02Citations (PDF)
101Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR
Cell, 2019, 177, 1201-1216.e19
35.1105Citations (PDF)
102IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses <i>In Vivo</i>9.739Citations (PDF)
103Metabolic Pathways Fueling the Endothelial Cell Drive
Annual Review of Physiology, 2019, 81, 483-503
17.9110Citations (PDF)
104Un nouveau rôle non métabolique de la glutamine synthétase au cours de l’angiogenèse
Medecine/Sciences, 2019, 35, 407-409
0.20Citations (PDF)
105The metabolic engine of endothelial cells
Nature Metabolism, 2019, 1, 937-946
11.989Citations (PDF)
106Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism2.468Citations (PDF)
107HIF-1α metabolically controls collagen synthesis and modification in chondrocytes
Nature, 2019, 565, 511-515
40.1195Citations (PDF)
108EndoDB: a database of endothelial cell transcriptomics data
Nucleic Acids Research, 2019, 47, D736-D744
16.268Citations (PDF)
109How glucose, glutamine and fatty acid metabolism shape blood and lymph vessel development
Developmental Biology, 2019, 447, 90-102
1.949Citations (PDF)
110Metabolic Reprogramming during Microglia Activation
Immunometabolism, 2019, 1,
2.823Citations (PDF)
111Blockade of Myeloid-Derived Suppressor Cell Expansion with All-<i>Trans</i> Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy
Cancer Research, 2018, 78, 3220-3232
0.692Citations (PDF)
112Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation14.1106Citations (PDF)
113The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
Cell Reports, 2018, 23, 1476-1490
6.4117Citations (PDF)
114Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging
Cell Stem Cell, 2018, 22, 769-778.e4
17.2276Citations (PDF)
115Endothelial Cell Metabolism
Physiological Reviews, 2018, 98, 3-58
26.6384Citations (PDF)
116Endothelial Cell Metabolism in Health and Disease
Trends in Cell Biology, 2018, 28, 224-236
15.3223Citations (PDF)
117Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice
Journal of Clinical Investigation, 2018, 128, 5008-5017
9.141Citations (PDF)
118Gas6 is dispensable for pubertal mammary gland development
PLoS ONE, 2018, 13, e0208550
2.510Citations (PDF)
119Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
Nature, 2018, 561, 63-69
40.1147Citations (PDF)
120Consensus guidelines for the use and interpretation of angiogenesis assays
Angiogenesis, 2018, 21, 425-532
7.4445Citations (PDF)
121Defective endothelial cell migration in the absence of Cdc42 leads to capillary-venous malformations3.045Citations (PDF)
122Live imaging reveals a conserved role of fatty acid β-oxidation in early lymphatic development in zebrafish2.13Citations (PDF)
123Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin14.198Citations (PDF)
124Phenotype molding of stromal cells in the lung tumor microenvironment
Nature Medicine, 2018, 24, 1277-1289
25.61,082Citations (PDF)
125Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells
Cell Metabolism, 2018, 28, 573-587.e13
26.3135Citations (PDF)
126Emerging Concepts in Organ-Specific Lymphatic Vessels and Metabolic Regulation of Lymphatic Development
Developmental Cell, 2018, 45, 289-301
7.854Citations (PDF)
127Effects of placental growth factor deficiency on behavior, neuroanatomy, and cerebrovasculature of mice
Physiological Genomics, 2018, 50, 862-875
2.521Citations (PDF)
128Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
Cell Metabolism, 2018, 28, 881-894.e13
26.3188Citations (PDF)
129Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
Cell Metabolism, 2018, 28, 866-880.e15
26.3174Citations (PDF)
130CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets
Cell Reports, 2018, 23, 3300-3311
6.470Citations (PDF)
131Stromal Gas6 promotes the progression of premalignant mammary cells
Oncogene, 2018, 38, 2437-2450
6.627Citations (PDF)
132Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia
Blood, 2018, 132, 759-759
1.00Citations (PDF)
133826: PlGF deficiency results in sFlt-1 elevation without the onset of preeclampsia in pregnant mice2.50Citations (PDF)
134Targeting endothelial metabolism for anti-angiogenesis therapy: A pharmacological perspective
Vascular Pharmacology, 2017, 90, 8-18
2.142Citations (PDF)
135Vessel pruning or healing: endothelial metabolism as a novel target?3.944Citations (PDF)
136The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling
Molecular Cell, 2017, 65, 885-899.e6
14.2168Citations (PDF)
137Interaction of endothelial cells with macrophages—linking molecular and metabolic signaling2.441Citations (PDF)
138Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity14.176Citations (PDF)
139Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism14.065Citations (PDF)
140Endothelial cell metabolism: an update anno 20173.035Citations (PDF)
141FGF-dependent metabolic control of vascular development
Nature, 2017, 545, 224-228
40.1271Citations (PDF)
142How to Cross the Lymphatic Fence
Circulation Research, 2017, 120, 1376-1378
12.83Citations (PDF)
143Vascular Endothelial Growth Factor Up-regulation in Human Amniotic Fluid Stem Cell Enhances Nephroprotection After Ischemia-Reperfusion Injury in the Rat
Critical Care Medicine, 2017, 45, e86-e96
0.623Citations (PDF)
144DOT1L safeguards cartilage homeostasis and protects against osteoarthritis14.1104Citations (PDF)
145Endothelial cell metabolism in health and disease: impact of hypoxia
EMBO Journal, 2017, 36, 2187-2203
7.4189Citations (PDF)
146Therapeutic Potential of Allosteric Modulation of FGF Receptors
2017, , 169-185
0Citations (PDF)
147Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction
Circulation, 2017, 136, 747-761
19.458Citations (PDF)
148CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions3.766Citations (PDF)
149Central Role of Metabolism in Endothelial Cell Function and Vascular Disease
Physiology, 2017, 32, 126-140
5.569Citations (PDF)
150Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells
Cell Reports, 2017, 18, 3005-3017
6.499Citations (PDF)
151Haematopoietic prolyl hydroxylase‐1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis
Journal of Pathology, 2017, 241, 547-558
5.232Citations (PDF)
152The Link Between Angiogenesis and Endothelial Metabolism17.9259Citations (PDF)
153Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2
Circulation, 2017, 136, 2451-2467
19.4194Citations (PDF)
154PP2A Inactivation Mediated by <i>PPP2R4</i> Haploinsufficiency Promotes Cancer Development
Cancer Research, 2017, 77, 6825-6837
0.633Citations (PDF)
155A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity
Cell Reports, 2017, 20, 2144-2155
6.4233Citations (PDF)
156Tumor vessel disintegration by maximum tolerable PFKFB3 blockade
Angiogenesis, 2017, 20, 599-613
7.470Citations (PDF)
157Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages
Journal of Leukocyte Biology, 2017, 102, 1115-1126
3.07Citations (PDF)
158Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes
Neurobiology of Disease, 2017, 108, 13-28
5.213Citations (PDF)
159Influences of placental growth factor on mouse retinal vascular development
Developmental Dynamics, 2017, 246, 700-712
1.710Citations (PDF)
160Role of glutamine and interlinked asparagine metabolism in vessel formation
EMBO Journal, 2017, 36, 2334-2352
7.4222Citations (PDF)
161Nogo-A regulates vascular network architecture in the postnatal brain4.917Citations (PDF)
162Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex
Cell Stem Cell, 2017, 20, 360-373.e7
17.261Citations (PDF)
163Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor–Sensitive and -Resistant Chronic Myeloid Leukemia
Clinical Cancer Research, 2017, 23, 2289-2300
6.433Citations (PDF)
164Angiogenesis revisited from a metabolic perspective: role and therapeutic implications of endothelial cell metabolism
Open Biology, 2017, 7, 170219
3.495Citations (PDF)
165How Endothelial Cells Adapt Their Metabolism to Form Vessels in Tumors5.086Citations (PDF)
166A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice
PLoS ONE, 2017, 12, e0180586
2.522Citations (PDF)
167Glycolytic adaptation and progression of kidney disease
Nature Reviews Nephrology, 2017, 14, 75-76
13.615Citations (PDF)
168Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
Journal of Clinical Investigation, 2017, 127, 3407-3420
9.173Citations (PDF)
169Author Response: Possibility of Cytoplasmic Transportation Between Donor–Host Cell Following Photoreceptor Transplantation
2016, 57, 5336
0Citations (PDF)
170Stem Cell–Derived Photoreceptor Transplants Differentially Integrate Into Mouse Models of Cone-Rod Dystrophy
2016, 57, 3509
71Citations (PDF)
171Manipulating Angiogenesis by Targeting Endothelial Metabolism: Hitting the Engine Rather than the Drivers—A New Perspective?
Pharmacological Reviews, 2016, 68, 872-887
16.442Citations (PDF)
172Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis
EMBO Journal, 2016, 35, 924-941
7.4151Citations (PDF)
173Meta‐analysis of clinical metabolic profiling studies in cancer: challenges and opportunities
EMBO Molecular Medicine, 2016, 8, 1134-1142
7.287Citations (PDF)
174Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner2.128Citations (PDF)
175Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia
European Heart Journal, 2016, 37, 2993-2997
2.242Citations (PDF)
176Improved metabolite identification with MIDAS and MAGMa through MS/MS spectral dataset-driven parameter optimization
Metabolomics, 2016, 12,
2.836Citations (PDF)
177Adequate hypoxia inducible factor 1α signaling is indispensable for bone regeneration
Bone, 2016, 87, 176-186
3.540Citations (PDF)
178Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression
Blood, 2016, 127, 2641-2644
1.024Citations (PDF)
179Endothelial cell metabolism: A novel player in atherosclerosis? Basic principles and therapeutic opportunities
Atherosclerosis, 2016, 253, 247-257
1.264Citations (PDF)
180Tumour hypoxia causes DNA hypermethylation by reducing TET activity
Nature, 2016, 537, 63-68
40.1483Citations (PDF)
181Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
Cancer Cell, 2016, 30, 968-985
33.4485Citations (PDF)
182De novo design of a biologically active amyloid
Science, 2016, 354,
38.260Citations (PDF)
183Glycolytic regulation of cell rearrangement in angiogenesis14.1130Citations (PDF)
184Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
Cell Metabolism, 2016, 24, 701-715
26.3379Citations (PDF)
185S84 Identification of MIR-124a as a major regulator of enhanced endothelial cell glycolysis in pulmonary arterial hypertension
Thorax, 2016, 71, A48.2-A49
4.82Citations (PDF)
186Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma
BMC Cancer, 2016, 16,
3.026Citations (PDF)
187Gas6 protein: its role in cardiovascular calcification
BMC Nephrology, 2016, 17,
2.218Citations (PDF)
188Placental growth factor deficiency is associated with impaired cerebral vascular development in mice
Molecular Human Reproduction, 2016, 22, 130-142
2.956Citations (PDF)
189Systemic sclerosis-like histopathological features in the myocardium of uPAR-deficient mice1.519Citations (PDF)
190The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A
Cell Reports, 2016, 14, 2653-2667
6.447Citations (PDF)
191PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity
Clinical Cancer Research, 2016, 22, 2993-3004
6.4110Citations (PDF)
192HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival
Cell Metabolism, 2016, 23, 265-279
26.3149Citations (PDF)
193Chloroquine anticancer activity is mediated by autophagy-independent effects on the tumor vasculature2.020Citations (PDF)
194Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism
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195Histamine Receptor H1–Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome
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196FOXO1 couples metabolic activity and growth state in the vascular endothelium
Nature, 2016, 529, 216-220
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197Targeting fatty acid metabolism in cancer and endothelial cells5.368Citations (PDF)
198The role of fatty acid β-oxidation in lymphangiogenesis
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199Vascular endothelial growth factor: a neurovascular target in neurological diseases
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200Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-139.132Citations (PDF)
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202Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow
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205P0290 : Placental growth factor inhibition modulates the interplay between hypoxia and the unfolded protein response in hepatocellular carcinoma
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206Metabolic Adaptations in Diabetic Endothelial Cells
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208Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways
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213Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways
Cell Reports, 2015, 10, 711-725
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214Meox2/Tcf15 Heterodimers Program the Heart Capillary Endothelium for Cardiac Fatty Acid Uptake
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215Placental Growth Factor Influences Maternal Cardiovascular Adaptation to Pregnancy in Mice12.726Citations (PDF)
216The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts
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217State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization12.8103Citations (PDF)
218Targeting endothelial cell metabolism: new therapeutic prospects?
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219Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Nature, 2015, 520, 192-197
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220Endothelial Cell Metabolism in Normal and Diseased Vasculature
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222Metabolic control of the cell cycle
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223Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds3.7119Citations (PDF)
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225Mitochondria in peroxisome-deficient hepatocytes exhibit impaired respiration, depleted DNA, and PGC-1α independent proliferation3.661Citations (PDF)
226Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and Is Associated With Akt Activation and HIF1α-VEGF Pathway Inhibition
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228The PHD2 oxygen sensor paves the way to metastasis
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230Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness
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231BGB324 Inhibits BCR-ABL TKI-Resistant Chronic Myeloid Leukemia
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236Age-Dependent Neonatal Intracerebral Hemorrhage in Plasminogen Activator Inhibitor 1 Knockout Mice1.912Citations (PDF)
237S138 Nanodiamond Delivery Of Vascular Endothelial Growth Factor Promotes Fetal Lung Development In A Rat Model Of Congenital Diaphragmatic Hernia
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238Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?1.574Citations (PDF)
239Endothelial Cell Differentiation by SOX17
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240Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy
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241Targeting VEGFR1 on endothelial progenitors modulates their differentiation potential
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242Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis
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244Hypoxia Induces VEGF-C Expression in Metastatic Tumor Cells via a HIF-1α-Independent Translation-Mediated Mechanism
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245Vascular endothelial growth factor‐loaded injectable hydrogel enhances plasticity in the injured spinal cord4.351Citations (PDF)
246Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
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247Allosteric targeting of receptor tyrosine kinases
Nature Biotechnology, 2014, 32, 1113-1120
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248HIF1 Activity in Granulosa Cells Is Required for FSH-Regulated Vegfa Expression and Follicle Survival in Mice12.739Citations (PDF)
249Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease
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250Fibroblast Growth Factor Signaling Affects Vascular Outgrowth and Is Required for the Maintenance of Blood Vessel Integrity
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251The multifaceted activity of VEGF in angiogenesis – Implications for therapy responses10.5118Citations (PDF)
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253Tumor Vessel Normalization by Chloroquine Independent of Autophagy
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254Tissue plasminogen activator arrests Alzheimer's disease pathogenesis
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255PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin
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256Metabolism of stromal and immune cells in health and disease
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257Bevacizumab and micrometastases: Revisiting the preclinical and clinical rollercoaster
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258P477Myeloid PHD-2 deficiency leads to enlarged and fibrotic atherosclerotic plaques in mice
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25913PHD1 deficiency promotes an atheroprotective metabolic phenotype
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260Essentials of Angiogenesis
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261Abstract IA17: Targeting placental growth factor/ neuropilin-1 pathway inhibits growth and spread of medulloblastoma
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262BGB324 Represents an Axl and BCR-ABL1 Inhibitor with Activity in the T315I Mutant
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263Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
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264The placental growth factor as a target against hepatocellular carcinoma in a diethylnitrosamine-induced mouse model
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265Matricellular proteins and matrix metalloproteinases mark the inflammatory and fibrotic response in human cardiac allograft rejection
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266PP2A regulatory subunit Bα controls endothelial contractility and vessel lumen integrity via regulation of HDAC7
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267Role of Endothelial Cell Metabolism in Vessel Sprouting
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268Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning2.053Citations (PDF)
269Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation
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270Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism4.389Citations (PDF)
271Markers of Response for the Antiangiogenic Agent Bevacizumab
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272Prominin-1 Allows Prospective Isolation of Neural Stem Cells from the Adult Murine Hippocampus
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273High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate
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274Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma
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278VEGF ligands and receptors: implications in neurodevelopment and neurodegeneration5.6140Citations (PDF)
279Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting
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280Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma
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281Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties
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282Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling
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283Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium
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284Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes8.1124Citations (PDF)
285A transgenic <i>Xenopus laevis</i> reporter model to study lymphangiogenesis
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286Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis
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288Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis
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289The NADPH oxidase Nox2 regulates VEGFR1/CSF‐1R‐mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex
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290The Fragile X Protein binds m <scp>RNA</scp> s involved in cancer progression and modulates metastasis formation
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291Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models
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292Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer
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293Hypoxia-Ischemia or Excitotoxin-Induced Tissue Plasminogen Activator- Dependent Gelatinase Activation in Mice Neonate Brain Microvessels
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294PAR1 contributes to influenza A virus pathogenicity in mice9.174Citations (PDF)
295Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance
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296Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia
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297Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis
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298MicroRNA Profiling Identifies MicroRNA-155 as an Adverse Mediator of Cardiac Injury and Dysfunction During Acute Viral Myocarditis
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299Phase II trial of erlotinib and bevacizumab in patients with advanced upper gastrointestinal cancers
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300PIGF Knockout Delays Brain Vessel Growth and Maturation upon Systemic Hypoxic Challenge4.932Citations (PDF)
301MOSAIC: A Multiscale Model of Osteogenesis and Sprouting Angiogenesis with Lateral Inhibition of Endothelial Cells
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302Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin7.739Citations (PDF)
303Placental Growth Factor Contributes to Bronchial Neutrophilic Inflammation and Edema in Allergic Asthma3.920Citations (PDF)
304Engineering Vascularized Bone: Osteogenic and Proangiogenic Potential of Murine Periosteal Cells
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305Inhibition of the placental growth factor decreases burden of cholangiocarcinoma and hepatocellular carcinoma in a transgenic mouse model1.412Citations (PDF)
306Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase
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307A breach in the blood–brain barrier
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308VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials
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310Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells
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311Peroxisome deficient aP2–Pex5 knockout mice display impaired white adipocyte and muscle function concomitant with reduced adrenergic tone0.918Citations (PDF)
312Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis
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313Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy
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314Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice
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315SnapShot: Tumor Angiogenesis
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316Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity
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317Prevalence of Prostate Cancer Metastases after Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment
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318PlGF: A Multitasking Cytokine with Disease-Restricted Activity6.7176Citations (PDF)
319VEGF Receptor-2 (Flk-1) Overexpression in Mice Counteracts Focal Epileptic Seizures
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320Neuroprotection by urokinase plasminogen activator in the hippocampus
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321Angiogenesis and the neurovascular link
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322Absence of microRNA‐155 protects against pressure overload‐induced cardiac inflammation and failure
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324TRPA1 underlies a sensing mechanism for O2
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325A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours
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326Basic and Therapeutic Aspects of Angiogenesis
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327Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications3.4175Citations (PDF)
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330VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1
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3331412 POSTER Genetic Markers in Relation to Bevacizumab-induced Hypertension
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3341414 POSTER Single Nucleotide Polymorphism Analysis and Outcome in Advanced-stage Cancer Patients Treated With Bevacizumab3.39Citations (PDF)
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340Molecular mechanisms and clinical applications of angiogenesis
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341Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties4.146Citations (PDF)
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344Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia
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345Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
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346Cerebrovascular disorders: molecular insights and therapeutic opportunities
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350Stem cell marker prominin‐1 regulates branching morphogenesis, but not regenerative capacity, in the mammary gland
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351Neuronal FLT1 receptor and its selective ligand VEGF‐B protect against retrograde degeneration of sensory neurons
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352Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models6.290Citations (PDF)
353Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?17.1141Citations (PDF)
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355Notch3 Arg170Cys Knock-In Mice Display Pathologic and Clinical Features of the Neurovascular Disorder Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy6.239Citations (PDF)
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358Carbohydrate Metabolism Is Perturbed in Peroxisome-deficient Hepatocytes Due to Mitochondrial Dysfunction, AMP-activated Protein Kinase (AMPK) Activation, and Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Suppression
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360Transient reduction of placental angiogenesis in PAI-1-deficient mice
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361Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
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362PlGF Repairs Myocardial Ischemia through Mechanisms of Angiogenesis, Cardioprotection and Recruitment of Myo-Angiogenic Competent Marrow Progenitors
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363Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease
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364Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6
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369Bridges that guide and unite
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370Role of Delta-like-4/Notch in the Formation and Wiring of the Lymphatic Network in Zebrafish6.2101Citations (PDF)
371Fumarase tumor suppressor gene and<i>MET</i>oncogene cooperate in upholding transformation and tumorigenesis
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372Matrix-Binding Vascular Endothelial Growth Factor (VEGF) Isoforms Guide Granule Cell Migration in the Cerebellum via VEGF Receptor Flk1
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378Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation
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382Anti–Placental Growth Factor Reduces Bone Metastasis by Blocking Tumor Cell Engraftment and Osteoclast Differentiation
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383Oxygen Sensing: A Common Crossroad in Cancer and Neurodegeneration0.021Citations (PDF)
384Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability
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385165 JNJ-26483327, a second-generation spectrum-targeted protein tyrosine kinase inhibitor with superior characteristics in advanced cancer models0.50Citations (PDF)
386Loss or Silencing of the PHD1 Prolyl Hydroxylase Protects Livers of Mice Against Ischemia/Reperfusion Injury
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387Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function
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388Mechanisms of Resistance to Anti-Angiogenic Therapy and Development of Third-Generation Anti-Angiogenic Drug Candidates
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389VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis
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390Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease
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391Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas
Developmental Biology, 2010, 347, 216-227
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392Placental growth factor mediates aldosterone-dependent vascular injury in mice
Journal of Clinical Investigation, 2010, 120, 3891-3900
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393NuSAP is essential for chromatin-induced spindle formation during early embryogenesis
Development (Cambridge), 2010, 137, e2006-e2006
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394Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration
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395Vascular Endothelial Growth Factor-B Induces Myocardium-Specific Angiogenesis and Arteriogenesis via Vascular Endothelial Growth Factor Receptor-1– and Neuropilin Receptor-1–Dependent Mechanisms
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396“Antimyeloangiogenic” Therapy for Cancer by Inhibiting PlGF
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397Growth Arrest Specific Protein 6 Participates in DOCA-Induced Target-Organ Damage
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398Loss of the Cholesterol-Binding Protein Prominin-1/CD133 Causes Disk Dysmorphogenesis and Photoreceptor Degeneration
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399G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway
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400Plasminogen Activator Inhibitor-1 Regulates Integrin αvβ3 Expression and Autocrine Transforming Growth Factor β Signaling
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401Mechanisms of Vessel Branching6.2311Citations (PDF)
402Oxygen-Induced Retinopathy in Mice: Amplification by Neonatal IGF-I Deficit and Attenuation by IGF-I Administration
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403Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells9.151Citations (PDF)
404Food‐restriction in obese dyslipidaemic diabetic mice partially restores basal contractility but not contractile reserve8.210Citations (PDF)
405Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction8.1178Citations (PDF)
406Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy
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407Fibrinolysis‐independent role of plasmin and its activators in the haematopoietic recovery after myeloablation4.120Citations (PDF)
408Silencing or Fueling Metastasis with VEGF Inhibitors: Antiangiogenesis Revisited
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409Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells3.632Citations (PDF)
410VEGF‐D deficiency in mice does not affect embryonic or postnatal lymphangiogenesis but reduces lymphatic metastasis
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411Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way25.3172Citations (PDF)
412Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease39.3291Citations (PDF)
413Role and Therapeutic Potential of VEGF in the Nervous System
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414Regulation of Angiogenesis by Oxygen and Metabolism
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415Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization
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416Oxygen Sensors at the Crossroad of Metabolism
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417The neurovascular link in health and disease: an update
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41816LBA VEGFR-1 polymorphisms as potential predictors of clinical outcome in bevacizumab-treated patients with metastatic pancreatic cancer0.59Citations (PDF)
419PP63 Predictive markers in patients with upper gastrointestinal (GI) cancers treated with erlotinib and bevacizumab in a multicenter phase II trial0.50Citations (PDF)
420Role of Placental Growth Factor in Mesenteric Neoangiogenesis in a Mouse Model of Portal Hypertension
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421Prevention of elastase-induced emphysema in placenta growth factor knock-out mice4.425Citations (PDF)
4226506 Predictive markers in patients with upper gastrointestinal cancers treated with erlotinib and bevacizumab in a multicenter phase II trial0.50Citations (PDF)
423Antibiotics may impair hematopoietic recovery after cytotoxic myeloablation
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424The FGF system has a key role in regulating vascular integrity
Journal of Clinical Investigation, 2009, 119, 2113-2113
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425Hypoxia Induces Dilated Cardiomyopathy in the Chick Embryo: Mechanism, Intervention, and Long-Term Consequences
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426Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury0.4235Citations (PDF)
427439: Intra-amniotic VEGF administration in fetal rats with nitrofen induced lung hypoplasia – A placebo controlled study2.50Citations (PDF)
428A lifeline for suffocating tissues
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429Neurovascular signalling defects in neurodegeneration
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430Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
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431Modeling lymphangiogenesis in a three-dimensional culture system
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432FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
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433Protective Role of Reactive Astrocytes in Brain Ischemia4.9427Citations (PDF)
434VEGFR‐2‐mediated increased proliferation and survival in response to oxygen and glucose deprivation in PlGF knockout astrocytes
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435Genetics, epigenetics and pharmaco‐(epi)genomics in angiogenesis4.150Citations (PDF)
436Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration
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437Heterozygous deficiency of the oxygen sensor PHD2 prevents metastasis by inducing vessel normalization0.50Citations (PDF)
438OC12. Specific inhibition of the VEGF homolog placental growth factor is protective against osteolytic bone metastasis in mice10.10Citations (PDF)
439264 DEFICIENCY IN PLACENTAL GROWTH FACTOR CAUSES A DECREASED PORTO-SYSTEMIC COLLATERAL VESSEL FORMATION IN PORTAL HYPERTENSIVE MICE
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440Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
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441Elevated levels of placental growth factor represent an adaptive host response in sepsis
Journal of Experimental Medicine, 2008, 205, 2623-2631
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442The von Hippel-Lindau Tumor Suppressor Protein and Egl-9-Type Proline Hydroxylases Regulate the Large Subunit of RNA Polymerase II in Response to Oxidative Stress
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443Abnormal Sympathoadrenal Development and Systemic Hypotension in <i>PHD3</i><sup><i>−</i>/<i>−</i></sup> Mice
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444Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling
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445Fibrinogen drives dystrophic muscle fibrosis via a TGFβ/alternative macrophage activation pathway
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446Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium6.293Citations (PDF)
447Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination
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448The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment
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449Metabolism and Therapeutic Angiogenesis
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450Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes
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451Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles
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452Plasmin therapy enhances mobilization of HPCs after G-CSF
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453Angiogenesis in the Central Nervous System
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454Role of Gas6 in erythropoiesis and anemia in mice9.176Citations (PDF)
455The FGF system has a key role in regulating vascular integrity
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456Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice
Journal of Clinical Investigation, 2008, 118, 3725-3737
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457Guidance of Vascular and Neuronal Network Formation
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458Disruption of GAS6-MER Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages
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459Increased Expression of Syndecan-1 Protects Against Cardiac Dilatation and Dysfunction After Myocardial Infarction
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460Hepatocyte Growth Factor Acts as a Motogen and Guidance Signal for Gonadotropin Hormone-Releasing Hormone-1 Neuronal Migration
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461Genetic Deletion of Placenta Growth Factor in Mice Alters Uterine NK Cells
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462Ttrap is an essential modulator of Smad3-dependent Nodal signaling during zebrafish gastrulation and left-right axis determination
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463uPA deficiency exacerbates muscular dystrophy in MDX mice
Journal of Cell Biology, 2007, 179, 165-165
4.81Citations (PDF)
464Tetralogy of Fallot and Alterations in Vascular Endothelial Growth Factor-A Signaling and Notch Signaling in Mouse Embryos Solely Expressing the VEGF120 Isoform
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465Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish
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466uPA deficiency exacerbates muscular dystrophy in <i>MDX</i> mice
Journal of Cell Biology, 2007, 178, 1039-1051
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467Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity7.7179Citations (PDF)
468NKT Cell-Derived Urokinase-Type Plasminogen Activator Promotes Peripheral Tolerance Associated with Eye
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469Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis
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470Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia
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471Heterogeneity in motoneuron disease
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472Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels
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473Tumoral and Choroidal Vascularization
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474Building in resistance to endothelial cell death
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475Similarities Between Angiogenesis and Neural Development: What Small Animal Models Can Tell Us0.054Citations (PDF)
476Antiangiogenic treatment with Sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats
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477Neonatal hypoxic preconditioning involves vascular endothelial growth factor
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478Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms
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479Modification of kidney barrier function by the urokinase receptor
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480Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice
Journal of Clinical Investigation, 2007, 117, 3188-3197
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481Vascular and Neuronal Development: Intersecting Parallelisms and rossroads
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482Retinal Angiogenesis and Growth Factors
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483Gas6 and Its Receptors Are Implicated in Sepsis as Modulators of Innate Immunity.
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484Zebrafish and Xenopus tadpoles: Small animal models to study angiogenesis and lymphangiogenesis
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485VEGF at the neurovascular interface: Therapeutic implications for motor neuron disease4.186Citations (PDF)
486Selective Regulation of Arterial Branching Morphogenesis by Synectin
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487Another angiogenic gene linked to amyotrophic lateral sclerosis
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488A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span2.048Citations (PDF)
489Gene prioritization through genomic data fusion
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490Fishing and frogging for anti-angiogenic drugs
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491VEGF inhibitors make blood
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492VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain
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493Pulmonary effects of antenatal intratracheal VEGF administration in preterm fetal rabbits2.50Citations (PDF)
494Evolution of Oxygen and Glucose Concentration Profiles in a Tissue-Mimetic Culture System of Embryonic Stem Cells4.237Citations (PDF)
495Altered VEGF-A isoform expression during embryogenesis affects arterial, venous and lymphatic differentiation
Vascular Pharmacology, 2006, 45, 193-194
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496VE-Cadherin-Cre-recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells
Developmental Dynamics, 2006, 235, 759-767
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497Implication of the hypoxia response element of the vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development
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498Overlap Syndrome of Cardiac Sodium Channel Disease in Mice Carrying the Equivalent Mutation of Human SCN5A -1795insD
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499Novel Transgenic Rabbit Model Sheds Light on the Puzzling Role of Matrix Metalloproteinase-12 in Atherosclerosis
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500Impaired Adipose Tissue Development in Mice With Inactivation of Placental Growth Factor Function
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501Altered Na+Channels Promote Pause-Induced Spontaneous Diastolic Activity in Long QT Syndrome Type 3 Myocytes
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502Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality
Journal of Experimental Medicine, 2006, 203, 1447-1458
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503Endogenous Tissue-Type Plasminogen Activator Is Protective during<i>Escherichia coli</i>-Induced Abdominal Sepsis in Mice
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504VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization
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505Inhibition of Urokinase-Type Plasminogen Activator or Matrix Metalloproteinases Prevents Cardiac Injury and Dysfunction During Viral Myocarditis
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506Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair
Journal of Clinical Investigation, 2006, 116, 1230-1242
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507Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis9.172Citations (PDF)
508Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts
Journal of Clinical Investigation, 2006, 116, 3150-3159
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509A New Mouse Model to Study Acquired Lymphedema
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510VEGF, an Angiogenic Factor with Neurotrophic Activity, Useful for Treatment of ALS?
2006, , 239-252
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511Vascular and Neuronal Effects of VEGF in the Nervous System
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512Plasminogen activator inhibitor-1 gene deficiency attenuates TGF-β1-induced kidney disease
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513Lymph makes you fat
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514A genetic Xenopus laevis tadpole model to study lymphangiogenesis
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515Common mechanisms of nerve and blood vessel wiring
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516Angiogenesis in life, disease and medicine
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517Genetic evidence for a tumor suppressor role of HIF-2α
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518Guidance of vascular and neural network formation5.0151Citations (PDF)
519Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications
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520Role of neural guidance signals in blood vessel navigation
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521Testosterone Suppresses Protective Responses of the Liver to Blood-Stage Malaria
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522The Zebrafish pob Gene Encodes a Novel Protein Required for Survival of Red Cone Photoreceptor CellsSequence data from this article have been deposited with the EMBL/GenBank Data Libraries under accession no. AY745978.
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523Placental Growth Factor Promotes Atherosclerotic Intimal Thickening and Macrophage Accumulation
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524Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A
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525A Novel Role for Vascular Endothelial Growth Factor as an Autocrine Survival Factor for Embryonic Stem Cells during Hypoxia
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526Gene targeting of VEGF-A in thymus epithelium disrupts thymus blood vessel architecture7.766Citations (PDF)
527Hypoxia-Inducible Factors 1α and 2α Regulate Trophoblast Differentiation
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528Novel Mutation in the Per-Arnt-Sim Domain of KCNH2 Causes a Malignant Form of Long-QT Syndrome
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529Role of Gas-6 in Adipogenesis and Nutritionally Induced Adipose Tissue Development in Mice6.237Citations (PDF)
530Increased Cardiac Expression of Tissue Inhibitor of Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-2 Is Related to Cardiac Fibrosis and Dysfunction in the Chronic Pressure-Overloaded Human Heart
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531Vascular Remodeling in Mice Lacking the Cytoplasmic Domain of Tissue Factor
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532Host Plasminogen Activator Inhibitor-1 Promotes Human Skin Carcinoma Progression in a Stage-Dependent Manner
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533Thrombophilia in mice expressing a tissue factor variant lacking its transmembrane and cytosolic domain2.12Citations (PDF)
534Fibrin-Induced Skin Fibrosis in Mice Deficient in Tissue Plasminogen Activator
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535Loss or Inhibition of uPA or MMP-9 Attenuates LV Remodeling and Dysfunction after Acute Pressure Overload in Mice3.6136Citations (PDF)
536Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors9.1142Citations (PDF)
537Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy9.1215Citations (PDF)
538Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A3.40Citations (PDF)
539The Nuclear Scaffold Protein NIPP1 Is Essential for Early Embryonic Development and Cell Proliferation
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540Dendritic Cell Subsets Differentially Regulate Angiogenesis in Human Ovarian Cancer
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541The Interferon Inducer Ampligen [Poly(I)-Poly(C 12 U)] Markedly Protects Mice against Coxsackie B3 Virus-Induced Myocarditis4.348Citations (PDF)
542Under stress, the absence of intermediate filaments from Müller cells in the retina has structural and functional consequences
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3.2115Citations (PDF)
543Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E–Deficient Mice Against Atherosclerotic Media Destruction but Differentially Affects Plaque Growth
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544Genetics in Zebrafish, Mice, and Humans to Dissect Congenital Heart Disease: Insights in the Role of VEGF0.031Citations (PDF)
545Role of Tissue-Derived Plasminogen Activator (t-PA) in an Excitotoxic Mouse Model of Neonatal White Matter Lesions1.916Citations (PDF)
546Manipulating angiogenesis in medicine
Journal of Internal Medicine, 2004, 255, 538-561
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547Plasmin is not protective in experimental renal interstitial fibrosis1
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548The European dimension for the mouse genome mutagenesis program
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549Regulation of angiogenesis by tissue factor cytoplasmic domain signaling
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550Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth
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551VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
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552The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
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553Genetic spotlight on a blood defect
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554Genetic dissection of tumor angiogenesis: are PlGF and VEGFR-1 novel anti-cancer targets?7.143Citations (PDF)
555VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection
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556A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis7.7621Citations (PDF)
557Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death
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558Title is missing!
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559Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity2.154Citations (PDF)
560Reduction in Arthritis Severity and Modulation of Immune Function in Tissue Factor Cytoplasmic Domain Mutant Mice
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561The Cytoplasmic Domain of Tissue Factor Contributes to Leukocyte Recruitment and Death in Endotoxemia
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562VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS?
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563Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration
Neurobiology of Disease, 2004, 17, 21-28
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564Role of vascular endothelial growth factor receptor 1 in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in mice
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565Angiogenesis and lymphangiogenesis: highlights of the past year3.019Citations (PDF)
566A CLEVER molecule that regulates lymphoctye trafficking
Blood, 2004, 104, 3840-3841
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567Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS
Nature Neuroscience, 2004, 8, 85-92
12.4425Citations (PDF)
568Soluble VEGF isoforms are essential for establishingepiphyseal vascularization and regulating chondrocyte development and survival9.1107Citations (PDF)
569Soluble VEGF isoforms are essential for establishingepiphyseal vascularization and regulating chondrocyte development and survival9.1216Citations (PDF)
570VEGF: a critical player in neurodegeneration9.182Citations (PDF)
571VEGF: a critical player in neurodegeneration9.1198Citations (PDF)
572Mouse Models to Study Pro-and Antiangiogenic Potential: Novel Roles for PLGF and FLT10.00Citations (PDF)
573Formation of Blood and Lymphatic Vessels: Role of Progenitors
2004, , 455-474
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574VASCULAR SMOOTH MUSCLE CELL APOPTOSIS IN ATHEROSCLEROTIC PLAQUES IS MEDIATED BY PLASMINOGEN ACTIVATION1.20Citations (PDF)
575VEGF and PlGF: two pleiotropic growth factors with distinct roles in development and homeostasis
Cell and Tissue Research, 2003, 314, 5-14
2.8137Citations (PDF)
576Stroma Formation and Angiogenesis by Overexpression of Growth Factors, Cytokines, and Proteolytic Enzymes in Human Skin Grafted to SCID Mice0.737Citations (PDF)
577Signalling silenced
Nature, 2003, 425, 139-140
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578VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
Nature Genetics, 2003, 34, 383-394
16.3739Citations (PDF)
579Angiogenesis in health and disease
Nature Medicine, 2003, 9, 653-660
25.63,504Citations (PDF)
580VEGF: A modifier of the del22q11 (DiGeorge) syndrome?
Nature Medicine, 2003, 9, 173-182
25.6280Citations (PDF)
581Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
Nature Medicine, 2003, 9, 936-943
25.6643Citations (PDF)
582Blood vessels and nerves: common signals, pathways and diseases
Nature Reviews Genetics, 2003, 4, 710-720
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583Role of the plasminogen system in basal adhesion formation and carbon dioxide pneumoperitoneum–enhanced adhesion formation after laparoscopic surgery in transgenic mice
Fertility and Sterility, 2003, 80, 184-192
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584Role of vascular endothelial growth factor and placental growth factor in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice
Fertility and Sterility, 2003, 80, 803-811
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585Role of hypoxia inducible factors 1α and 2α in basal adhesion formation and in carbon dioxide pneumoperitoneum-enhanced adhesion formation after laparoscopic surgery in transgenic mice
Fertility and Sterility, 2003, 80, 795-802
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5861P-0210 Effects of endogenous placental growth factor on vascular permeability in pathological conditions2.10Citations (PDF)
587Bone marrow transplantation abolishes inhibition of arteriogenesis in placenta growth factor (PlGF) –/– mice2.048Citations (PDF)
588Title is missing!
Arthritis Research, 2003, 5, R9
4.638Citations (PDF)
589Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1α
Cardiovascular Research, 2003, 60, 569-579
5.6157Citations (PDF)
590Urokinase Receptor Modulates Cellular and Angiogenic Responses in Obstructive Nephropathy0.450Citations (PDF)
591VEGFR-1–Selective VEGF Homologue PlGF Is Arteriogenic
Circulation Research, 2003, 92, 378-385
12.8260Citations (PDF)
592Urokinase Receptor Deficiency Accelerates Renal Fibrosis in Obstructive Nephropathy0.4103Citations (PDF)
593Type 1 plasminogen activator inhibitor deficiency aggravates the course of experimental glomerulonephritis through overactivation of transforming growth factor β
FASEB Journal, 2003, 17, 1-24
0.748Citations (PDF)
594Plasminogen Activator Inhibitor-1 Is a Significant Determinant of Renal Injury in Experimental Crescentic Glomerulonephritis0.471Citations (PDF)
595Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin
Circulation Research, 2003, 93, 1120-1126
12.826Citations (PDF)
596Urokinase-Type Plasminogen Activator Plays a Critical Role in Angiotensin II–Induced Abdominal Aortic Aneurysm
Circulation Research, 2003, 92, 510-517
12.8154Citations (PDF)
597Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata
Human Molecular Genetics, 2003, 12, 2255-2267
3.193Citations (PDF)
598Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in ΔKPQ SCN5A (long QT3) mice
Cardiovascular Research, 2003, 57, 1085-1093
5.673Citations (PDF)
599De novo vasculogenesis in the heart
Cardiovascular Research, 2003, 58, 378-389
5.681Citations (PDF)
600A critical role of placental growth factor in the induction of inflammation and edema formation
Blood, 2003, 101, 560-567
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601Plasminogen activator inhibitor type–1 deficiency does not influence the outcome of murine pneumococcal pneumonia
Blood, 2003, 102, 934-939
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602Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C–deficient mice
Blood, 2003, 101, 4823-4827
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603Mice without uPA, tPA, or Plasminogen Genes Are Resistant to Experimental Choroidal Neovascularization
2003, 44, 1732
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604Placental Growth Factor, a Member of the VEGF Family, Contributes to the Development of Choroidal Neovascularization
2003, 44, 3186
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605Dose-Dependent Modulation of Choroidal Neovascularization by Plasminogen Activator Inhibitor Type I: Implications for Clinical Trials
2003, 44, 2791
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606Neuronal Migration Depends on Intact Peroxisomal Function in Brain and in Extraneuronal Tissues
Journal of Neuroscience, 2003, 23, 9732-9741
3.753Citations (PDF)
607Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
Journal of Clinical Investigation, 2003, 111, 1519-1527
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608Soluble VEGF receptor Flt1: the elusive preeclampsia factor discovered?9.1117Citations (PDF)
609Urokinase Receptor Is Necessary for Adequate Host Defense Against Pneumococcal Pneumonia
Journal of Immunology, 2002, 168, 3507-3511
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610Plasminogen Activator Inhibitor 1 and Vitronectin Protect Against Stenosis in a Murine Carotid Artery Ligation Model6.261Citations (PDF)
611Cell Type-Specific Expression of Neuropilins in an MCA-Occlusion Model in Mice Suggests a Potential Role in Post-Ischemic Brain Remodeling1.994Citations (PDF)
612Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice7.7189Citations (PDF)
613The pro‐ or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent
FASEB Journal, 2002, 16, 147-154
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614Loss of the VEGF164 and VEGF188 Isoforms Impairs Postnatal Glomerular Angiogenesis and Renal Arteriogenesis in Mice0.490Citations (PDF)
615Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo
Blood, 2002, 99, 2835-2844
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616Smad3-Dependent Induction of Plasminogen Activator Inhibitor-1 in Astrocytes Mediates Neuroprotective Activity of Transforming Growth Factor-β1 against NMDA-Induced Necrosis2.273Citations (PDF)
617Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders5.4215Citations (PDF)
618Introduction5.40Citations (PDF)
619Loss of placental growth factor protects mice against vascular permeability in pathological conditions2.176Citations (PDF)
620Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
Mechanisms of Development, 2002, 111, 61-73
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621Vascular Progenitors From Biology to Treatment7.2157Citations (PDF)
622Integrin indecision
Nature Medicine, 2002, 8, 14-16
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623Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
Nature Medicine, 2002, 8, 702-710
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624Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
Nature Medicine, 2002, 8, 831-840
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625uPAR: a versatile signalling orchestrator31.41,074Citations (PDF)
626Placental Growth Factor (PlGF) and Its Receptor Flt‐1 (VEGFR‐1)4.5180Citations (PDF)
627Molecular mechanisms of lymphangiogenesis in health and disease
Cancer Cell, 2002, 1, 219-227
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628Mouse aortic ring assay: A new approach of the molecular genetics of angiogenesis4.2112Citations (PDF)
629Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy
EMBO Journal, 2002, 21, 1939-1947
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630The Development of Blood Vessels: Cellular and Molecular Mechanisms
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631Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms9.1341Citations (PDF)
632Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms9.1206Citations (PDF)
633Molecular and Cellular Angiogenesis
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634Molecular mechanisms of blood vessel growth
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635Targeted Deletion of the Cytosolic Domain of Tissue Factor in Mice Does Not Affect Development2.143Citations (PDF)
636Heterogeneous Vascular Dependence of Tumor Cell Populations
American Journal of Pathology, 2001, 158, 1325-1334
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637Urokinase but not tissue-type plasminogen activator is involved in collateral artery growth2.00Citations (PDF)
638Impaired liver regeneration after partial hepatectomy in plasminogen deficient mice0.29Citations (PDF)
639Urokinase-dependent plasminogen activation is required for efficient skeletal muscle regeneration in vivo
Blood, 2001, 97, 1703-1711
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640The Emerging Role of the Bone Marrow-Derived Stem Cells in (Therapeutic) Angiogenesis
Thrombosis and Haemostasis, 2001, 86, 289-297
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641The pathophysiology of pelvic floor disorders: evidence from a histomorphologic study of the perineum and a mouse model of rectal prolapse
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642Increased stromal expression of murine urokinase plasminogen activator in a human breast cancer xenograft model following treatment with the matrix metalloprotease inhibitor, batimastat2.511Citations (PDF)
643The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling
Nature Medicine, 2001, 7, 59-64
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644Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis
Nature Medicine, 2001, 7, 215-221
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645Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
Nature Medicine, 2001, 7, 575-583
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646Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
Nature Genetics, 2001, 28, 131-138
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647In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy
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648Growing better blood vessels
Nature Biotechnology, 2001, 19, 1019-1020
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649Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome
Nature Medicine, 2001, 7, 1021-1027
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650Jeffrey Michael Isner 1947-2001
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651Creating unique blood vessels
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652Duodenal calcium absorption in vitamin D receptor-knockout mice: Functional and molecular aspects7.7509Citations (PDF)
653Bmx Tyrosine Kinase Has a Redundant Function Downstream of Angiopoietin and Vascular Endothelial Growth Factor Receptors in Arterial Endothelium
Molecular and Cellular Biology, 2001, 21, 4647-4655
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654Tissue-Type Plasminogen Activator Deficiency Exacerbates Arthritis
Journal of Immunology, 2001, 167, 1047-1052
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655Hypoxia-inducible Factor-2α (HIF-2α) Is Involved in the Apoptotic Response to Hypoglycemia but Not to Hypoxia
Journal of Biological Chemistry, 2001, 276, 39192-39196
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656The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin
Journal of Cell Biology, 2001, 152, 777-784
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657Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization
FASEB Journal, 2001, 15, 1021-1027
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658Blood Coagulation Factor X Deficiency Causes Partial Embryonic Lethality and Fatal Neonatal Bleeding in Mice
Thrombosis and Haemostasis, 2000, 83, 185-190
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659Transgenic mouse models in angiogenesis and cardiovascular disease
2000, 190, 387-405
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660PR39, a peptide regulator of angiogenesis
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661Mechanisms of angiogenesis and arteriogenesis
Nature Medicine, 2000, 6, 389-395
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662VEGF gene therapy: stimulating angiogenesis or angioma-genesis?
Nature Medicine, 2000, 6, 1102-1103
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663Angiogenesis in cancer and other diseases
Nature, 2000, 407, 249-257
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664One cell, two fates
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665Roles of urokinase type plasminogen activator in a brain stab wound
Brain Research, 2000, 887, 187-190
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666The role of proteinases in angiogenesis, heart development, restenosis, atherosclerosis, myocardial ischemia, and stroke: Insights from genetic studies4.958Citations (PDF)
667Characterization of the vasculogenic block in the absence of vascular endothelial growth factor-A
Blood, 2000, 95, 1979-1987
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668Inactivation of the Peroxisomal Multifunctional Protein-2 in Mice Impedes the Degradation of Not Only 2-Methyl-branched Fatty Acids and Bile Acid Intermediates but Also of Very Long Chain Fatty Acids
Journal of Biological Chemistry, 2000, 275, 16329-16336
2.3168Citations (PDF)
669Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene <i>ngn3</i>
Molecular and Cellular Biology, 2000, 20, 4445-4454
2.5284Citations (PDF)
670Disruption of the Plasminogen Gene in Mice Abolishes Wound Healing after Myocardial Infarction
American Journal of Pathology, 2000, 156, 1865-1873
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671Molecular Basis of Angiogenesis: Role of VEGF and VE‐Cadherin4.5229Citations (PDF)
672Proteinases in cardiovascular aneurysms and rupture: targets for therapy?
Journal of Clinical Investigation, 2000, 105, 1519-1520
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673Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility
Journal of Clinical Investigation, 2000, 106, 1531-1539
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675A Role of Plasminogen in Atherosclerosis and Restenosis Models in Mice4.443Citations (PDF)
676Structure-Function Analyses of Thrombomodulin by Gene-Targeting in Mice: The Cytoplasmic Domain Is Not Required for Normal Fetal Development
Blood, 1999, 93, 3442-3450
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677Ovulation in Plasminogen-Deficient Mice<sup>1</sup>
Endocrinology, 1999, 140, 5030-5035
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678Plasminogen Is Not Required for Neointima Formation in a Mouse Model of Vein Graft Stenosis
Circulation Research, 1999, 84, 883-890
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679Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
Nature Medicine, 1999, 5, 1135-1142
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680Controlling the cellular brakes
Nature, 1999, 401, 657-658
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681Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188
Nature Medicine, 1999, 5, 495-502
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682Regulation of cancer invasion and vascularization by plasminogen activator inhibitor-1
Fibrinolysis and Proteolysis, 1999, 13, 220-225
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683Nigral degeneration following striato-pallidal lesion in tissue type plasminogen activator deficient mice
Neuroscience Letters, 1999, 266, 220-222
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684Plasminogen and cell migration in vivo0.230Citations (PDF)
685Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis
Cell, 1999, 98, 147-157
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686Animal models of cardiovascular disease
Atherosclerosis, 1999, 144, 163
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687Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit9.144Citations (PDF)
688Ovulation in Plasminogen-Deficient Mice
Endocrinology, 1999, 140, 5030-5035
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689Molecular Analysis of Vascular Development and Disorders0.00Citations (PDF)
690Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
Nature, 1998, 394, 485-490
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691Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization
Nature Medicine, 1998, 4, 923-928
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692Vascular development and disorders: Molecular analysis and pathogenic insights
Kidney International, 1998, 53, 1519-1549
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693Urokinase mediates bFGF-induced vascular smooth muscle cell migration under the control of TGFβ0.21Citations (PDF)
694Molecules in focus Tissue factor2.654Citations (PDF)
695Development and Disease in Proteinase-Deficient Mice
Thrombosis Research, 1998, 91, 255-285
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696Function of the Plasminogen/Plasmin and Matrix Metalloproteinase Systems After Vascular Injury in Mice With Targeted Inactivation of Fibrinolytic System Genes6.2205Citations (PDF)
697Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice
Journal of Cell Biology, 1998, 140, 233-245
4.8117Citations (PDF)
698Plasminogen Deficiency Differentially Affects Recruitment of Inflammatory Cell Populations in Mice
Blood, 1998, 91, 2005-2009
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699Cloning and Characterization of a cDNA Encoding Murine Coagulation Factor X4.410Citations (PDF)
700Nucleotide Structure and Characterization of the Murine Gene Encoding Anticoagulant Protein C
Thrombosis and Haemostasis, 1998, 79, 310-316
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701Role of Endothelial versus Smooth Muscle Cells in Blood Vessel Formation
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702Role of the Fibrinolytic and the Coagulation System in the Formation and Disorders of Blood Vessels0.00Citations (PDF)
703Plasminogen and Plasminogen Activators Protect against Renal Injury in Crescentic Glomerulonephritis8.1175Citations (PDF)
704Urokinase and Tissue-type Plasminogen Activator Are Required for the Mitogenic and Chemotactic Effects of Bovine Fibroblast Growth Factor and Platelet-derived Growth Factor-BB for Vascular Smooth Muscle Cells
Journal of Biological Chemistry, 1997, 272, 23585-23591
2.355Citations (PDF)
705Molecular genetics of the fibrinolytic and coagulation systems in haemostasis, thrombogenesis, restenosis and atherosclerosis4.127Citations (PDF)
706Insights from gene-inactivation studies of the coagulation and plasminogen
Fibrinolysis and Proteolysis, 1997, 11, 181-191
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707Molecular analysis of blood vessel formation and disease3.978Citations (PDF)
708Adenovirus-Mediated Transfer of Tissue-Type Plasminogen Activator Augments Thrombolysis in Tissue-Type Plasminogen Activator–Deficient and Plasminogen Activator Inhibitor-1–Overexpressing Mice
Blood, 1997, 90, 1527-1534
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709Insights in Vessel Development and Vascular Disorders Using Targeted Inactivation and Transfer of Vascular Endothelial Growth Factor, the Tissue Factor Receptor, and the Plasminogen System4.5113Citations (PDF)
710A mouse model for Zellweger syndrome
Nature Genetics, 1997, 17, 49-57
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711Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation
Nature Genetics, 1997, 17, 439-444
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712Mice lacking factor VII develop normally but suffer fatal perinatal bleeding
Nature, 1997, 390, 290-294
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713Genetic Analysis of Blood Vessel Formation7.239Citations (PDF)
714Studies of Mice Lacking Plasminogen Activator Gene Function Suggest that Plasmin Production Prior to Ovulation Exceeds the Amount Needed for Optimal Ovulation Efficiency
FEBS Journal, 1997, 244, 487-493
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715Polyoma Middle T-induced Vascular Tumor Formation: The Role of the Plasminogen Activator/Plasmin System
Journal of Cell Biology, 1997, 137, 953-963
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716Inhibitory Role of Plasminogen Activator Inhibitor-1 in Arterial Wound Healing and Neointima Formation
Circulation, 1997, 96, 3180-3191
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717Urokinase but Not Tissue Plasminogen Activator Mediates Arterial Neointima Formation in Mice
Circulation Research, 1997, 81, 829-839
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718Biological Effects of Targeted Gene Inactivation and Gene Transfer of the Coagulation and Fibrinolytic Systems in Mice
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719Nucleotide Structure and Characterization of the Murine Blood Coagulation Factor VII Gene
Thrombosis and Haemostasis, 1996, 76, 0957-0964
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720Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.7.7310Citations (PDF)
721Targeted gene manipulation and transfer of the plasminogen and coagulation systems in mice
Fibrinolysis, 1996, 10, 195-213
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722Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
Nature, 1996, 380, 435-439
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723Role of tissue factor in embryonic blood vessel development
Nature, 1996, 383, 73-75
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724Gene Manipulation and Transfer of the Plasminogen and Coagulation System in Mice3.149Citations (PDF)
725Bone resorption and response to calcium-regulating hormones in the absence of tissue or urokinase plasminogen activator or of their type 1 inhibitor5.110Citations (PDF)
726Characterization of a cDNA Encoding Murine Coagulation Factor VII
Thrombosis and Haemostasis, 1996, 75, 481-487
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727Role of the plasminogen/plasmin system in thrombosis, hemostasis, restenosis and atherosclerosis evaluation in transgenic animals7.229Citations (PDF)
728Gene targeting and gene transfer studies of the plaeminogen/plasmin system: implications in thrombosis, hemostasis, neointima formation, and atherosclerosis
FASEB Journal, 1995, 9, 934-938
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729Generation of Monoclonal Antibodies against Autologous Proteins in Gene-inactivated Mice
Journal of Biological Chemistry, 1995, 270, 8397-8400
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730Gene Targeting and Gene Transfer Studies of the Biological Role of the Plasminogen/Plasmin System
Thrombosis and Haemostasis, 1995, 74, 429-436
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731Biological Effects of Combined Inactivation of Plasminogen Activator and Plasminogen Activator Inhibitor-1 Gene Function in Mice
Thrombosis and Haemostasis, 1995, 74, 1126-1131
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732Effects of Disruption of The Plasminogen Gene on Thrombosis, Growth, and Health in Mice
Circulation, 1995, 92, 2585-2593
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733Physiological consequences of loss of plasminogen activator gene function in mice
Nature, 1994, 368, 419-424
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734Evaluation of the plasminogen/plasmin system in transgenic mice
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735Biological effects of inactivation of the genes for tissue-type plasminogen activator, urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in mice
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736Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.9.1295Citations (PDF)
737Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.9.1326Citations (PDF)
738Interferon-7 Inhibits Stimulated Adrenocorticotropin, Prolactin, and Growth Hormone Secretion in Normal Rat Anterior Pituitary Cell Cultures*
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739Regulation and Cellular Localization of the Membrane Bound Thyrotropin-Releasing Hormone-Degrading Enzyme in Primary Cultures of Neuronal, Glial and Adenohypophyseal Cells*
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740Interleukin-1β inhibits acetylcholine synthesis in the pituitary corticotropic cell line AtT20
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741Synthesis and Release of Acetylcholine by Normal and Tumoral Pituitary Corticotrophs*
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742Cell-to-cell communication in peptide target cells of anterior pituitary
Methods in Enzymology, 1989, , 47-72
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743Immunocytochemical and Pharmacological Evidence for an Intrinsic Cholinomimetic System Modulating Prolactin and Growth Hormone Release in Rat Pituitary*
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744Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
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745Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function1.00Citations (PDF)