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136 peer-reviewed articles • 15,343 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Exploring the potential role of palladin in modulating human CAF / ECM functional units
Cytoskeleton, 2025, 82, 175-185
1.51Citations (PDF)
2PAK2 is necessary for myelination in the peripheral nervous system
Brain, 2024, 147, 1809-1821
8.49Citations (PDF)
3Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity2.811Citations (PDF)
4PAK2 Is Necessary for Myelination in the Peripheral Nerve System (S21.009)
Neurology, 2024, 102,
1.00Citations (PDF)
5E proteins control the development of NKγδT cells through their invariant T cell receptor13.75Citations (PDF)
6FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs13.710Citations (PDF)
7Impact of primary sequence changes on the self‐association properties of mammalian cystathionine beta‐synthase enzymes
Protein Science, 2024, 33,
5.91Citations (PDF)
8Queer voices in computational biology: the first ISCB LGBTQI+ Symposium2.41Citations (PDF)
9The protein common assembly database (ProtCAD)—a comprehensive structural resource of protein complexes
Nucleic Acids Research, 2023, 51, D466-D478
15.56Citations (PDF)
10Palmitoylation-dependent control of JAK1 kinase signaling governs responses to neuropoietic cytokines and survival in DRG neurons2.214Citations (PDF)
11Kincore: a web resource for structural classification of protein kinases and their inhibitors
Nucleic Acids Research, 2022, 50, D654-D664
15.5106Citations (PDF)
12PDBe-KB: collaboratively defining the biological context of structural data
Nucleic Acids Research, 2022, 50, D534-D542
15.587Citations (PDF)
13The ERK2 DBP domain opposes pathogenesis of a JAK2V617F-driven myeloproliferative neoplasm
Blood, 2022, ,
4.81Citations (PDF)
14Delineating the RAS Conformational Landscape
Cancer Research, 2022, 82, 2485-2498
3.828Citations (PDF)
15Development and Utility of a PAK1-Selective Degrader
Journal of Medicinal Chemistry, 2022, 65, 15627-15641
5.624Citations (PDF)
16Structure of TFIIK for phosphorylation of CTD of RNA polymerase II
Science Advances, 2021, 7,
10.918Citations (PDF)
17PyRosetta Jupyter Notebooks Teach Biomolecular Structure Prediction and Design
The Biophysicist, 2021, 2, 108-122
0.315Citations (PDF)
18PDBrenum: A webserver and program providing Protein Data Bank files renumbered according to their UniProt sequences
PLoS ONE, 2021, 16, e0253411
2.334Citations (PDF)
19Better together: Elements of successful scientific software development in a distributed collaborative community
PLoS Computational Biology, 2020, 16, e1007507
3.141Citations (PDF)
20Multifaceted analysis of training and testing convolutional neural networks for protein secondary structure prediction
PLoS ONE, 2020, 15, e0232528
2.317Citations (PDF)
21ProtCID: a data resource for structural information on protein interactions13.755Citations (PDF)
22Protein modeling to assess the pathogenicity of rare variants of SERPINA1 in patients suspected of having Alpha 1 Antitrypsin Deficiency1.818Citations (PDF)
23Interaction of germline variants in a family with a history of early‐onset clear cell renal cell carcinoma1.611Citations (PDF)
24Defining a new nomenclature for the structures of active and inactive kinases7.5348Citations (PDF)
25A new clustering and nomenclature for beta turns derived from high-resolution protein structures
PLoS Computational Biology, 2019, 15, e1006844
3.184Citations (PDF)
26Principles and characteristics of biological assemblies in experimentally determined protein structures6.418Citations (PDF)
27A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains3.4124Citations (PDF)
28Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling
Neoplasia, 2018, 20, 244-255
7.023Citations (PDF)
29Role of a selecting ligand in shaping the murine γδ-TCR repertoire7.560Citations (PDF)
30Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity2.68Citations (PDF)
31RosettaAntibodyDesign (RAbD): A general framework for computational antibody design
PLoS Computational Biology, 2018, 14, e1006112
3.1215Citations (PDF)
32Mouse modeling and structural analysis of the p.G307S mutation in human cystathionine β-synthase (CBS) reveal effects on CBS activity but not stability
Journal of Biological Chemistry, 2018, 293, 13921-13931
2.216Citations (PDF)
33The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design5.11,550Citations (PDF)
34Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods
Cancer Biology and Therapy, 2017, 18, 519-533
4.125Citations (PDF)
35Biological function derived from predicted structures in CASP112.69Citations (PDF)
36CASP 11 target classification2.633Citations (PDF)
37Assessment of refinement of template‐based models in CASP112.640Citations (PDF)
38Assessment of template‐based modeling of protein structure in CASP112.630Citations (PDF)
39Cancer Signature Investigation:<i>ERBB2</i>(<i>HER2</i>)-Activating Mutation and Amplification-Positive Breast Carcinoma Mimicking Lung Primary12.614Citations (PDF)
40The Origin of CDR H3 Structural Diversity
Structure, 2015, 23, 302-311
3.8104Citations (PDF)
41Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer
European Urology, 2015, 68, 959-967
2.1481Citations (PDF)
42Characteristics of clinical trials that require participants to be fluent in English
Clinical Trials, 2015, 12, 618-626
1.840Citations (PDF)
43PyIgClassify: a database of antibody CDR structural classifications
Nucleic Acids Research, 2015, 43, D432-D438
15.5127Citations (PDF)
44Identifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinases5.446Citations (PDF)
45Conformational Analysis of the DFG-Out Kinase Motif and Biochemical Profiling of Structurally Validated Type II Inhibitors5.6236Citations (PDF)
46Issues in interpreting thein vivoactivity of Aurora-A3.722Citations (PDF)
47Acetylation of the Transcriptional Repressor Ume6p Allows Efficient Promoter Release and Timely Induction of the Meiotic Transient Transcription Program in Yeast2.523Citations (PDF)
48BioAssemblyModeler (BAM): User-Friendly Homology Modeling of Protein Homo- and Heterooligomers
PLoS ONE, 2014, 9, e98309
2.316Citations (PDF)
49Charge asymmetry in the proteins of the outer membrane
Bioinformatics, 2013, 29, 2122-2128
4.756Citations (PDF)
50A new model for allosteric regulation of phenylalanine hydroxylase: Implications for disease and therapeutics2.858Citations (PDF)
51A Modified HSP70 Inhibitor Shows Broad Activity as an Anticancer Agent
Molecular Cancer Research, 2013, 11, 219-229
3.1101Citations (PDF)
52Prediction of phenotypes of missense mutations in human proteins from biological assemblies2.623Citations (PDF)
53A Highly Selective Dual Insulin Receptor (IR)/Insulin-like Growth Factor 1 Receptor (IGF-1R) Inhibitor Derived from an Extracellular Signal-regulated Kinase (ERK) Inhibitor
Journal of Biological Chemistry, 2013, 288, 28068-28077
2.216Citations (PDF)
54Architecture and Assembly of HIV Integrase Multimers in the Absence of DNA Substrates
Journal of Biological Chemistry, 2013, 288, 7373-7386
2.229Citations (PDF)
55The PyRosetta Toolkit: A Graphical User Interface for the Rosetta Software Suite
PLoS ONE, 2013, 8, e66856
2.335Citations (PDF)
56The Role of Balanced Training and Testing Data Sets for Binary Classifiers in Bioinformatics
PLoS ONE, 2013, 8, e67863
2.3261Citations (PDF)
57Abstract A291: A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an ERK inhibitor.
Molecular Cancer Therapeutics, 2013, 12, A291-A291
1.91Citations (PDF)
58Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB
Bioinformatics, 2012, 28, 2763-2772
4.761Citations (PDF)
59Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites7.568Citations (PDF)
60CD45-deficient severe combined immunodeficiency caused by uniparental disomy7.582Citations (PDF)
61Minimal ensembles of side chain conformers for modeling protein–protein interactions2.627Citations (PDF)
62Aurora A kinase (AURKA) in normal and pathological cell division5.5416Citations (PDF)
63The protein common interface database (ProtCID)--a comprehensive database of interactions of homologous proteins in multiple crystal forms
Nucleic Acids Research, 2011, 39, D761-D770
15.582Citations (PDF)
64A New Clustering of Antibody CDR Loop Conformations
Journal of Molecular Biology, 2011, 406, 228-256
4.1407Citations (PDF)
65Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer
Drug Resistance Updates, 2011, 14, 260-279
19.232Citations (PDF)
66A Smoothed Backbone-Dependent Rotamer Library for Proteins Derived from Adaptive Kernel Density Estimates and Regressions
Structure, 2011, 19, 844-858
3.81,006Citations (PDF)
67PONDR-FIT: A meta-predictor of intrinsically disordered amino acids2.01,179Citations (PDF)
68Testing computational prediction of missense mutation phenotypes: Functional characterization of 204 mutations of human cystathionine beta synthase2.667Citations (PDF)
69Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation7.5247Citations (PDF)
70A Bifunctional Regulatory Element in Human Somatic Wee1 Mediates Cyclin A/Cdk2 Binding and Crm1-Dependent Nuclear Export2.543Citations (PDF)
71Numb Independently Antagonizes Sanpodo Membrane Targeting and Notch Signaling in Drosophila Sensory Organ Precursor Cells2.541Citations (PDF)
72Neighbor-Dependent Ramachandran Probability Distributions of Amino Acids Developed from a Hierarchical Dirichlet Process Model
PLoS Computational Biology, 2010, 6, e1000763
3.1163Citations (PDF)
73Clinical Trials That Explicitly Exclude Gay and Lesbian Patients
New England Journal of Medicine, 2010, 362, 1054-1055
34.535Citations (PDF)
74Rapid calcium-dependent activation of Aurora-A kinase13.778Citations (PDF)
75Development of a Rotamer Library for Use in β-Peptide Foldamer Computational Design15.038Citations (PDF)
76Mixed Quantum Mechanics/Molecular Mechanics Scoring Function To Predict Protein−Ligand Binding Affinity5.186Citations (PDF)
77Outcome of a Workshop on Applications of Protein Models in Biomedical Research
Structure, 2009, 17, 151-159
3.8147Citations (PDF)
78Conformation Dependence of Backbone Geometry in Proteins
Structure, 2009, 17, 1316-1325
3.8104Citations (PDF)
79An unusually small dimer interface is observed in all available crystal structures of cytosolic sulfotransferases2.621Citations (PDF)
80Improved prediction of protein side‐chain conformations with SCWRL42.61,302Citations (PDF)
81A forward-looking suggestion for resolving the stereochemical restraints debate: ideal geometry functions3.114Citations (PDF)
82Statistical Analysis of Interface Similarity in Crystals of Homologous Proteins
Journal of Molecular Biology, 2008, 381, 487-507
4.1105Citations (PDF)
83Oligomerization of BAK by p53 Utilizes Conserved Residues of the p53 DNA Binding Domain
Journal of Biological Chemistry, 2008, 283, 21294-21304
2.285Citations (PDF)
84Statistical and conformational analysis of the electron density of protein side chains2.650Citations (PDF)
85Two Potentially Important Elements of the Hepatitis B Virus Large Envelope Protein Are Dispensable for the Infectivity of Hepatitis Delta Virus
Journal of Virology, 2007, 81, 4343-4347
3.632Citations (PDF)
86ProtBuD: a database of biological unit structures of protein families and superfamilies
Bioinformatics, 2007, 23, 2028-2028
4.70Citations (PDF)
87BioDownloader: bioinformatics downloads and updates in a few clicks
Bioinformatics, 2007, 23, 1437-1439
4.74Citations (PDF)
88Structure of a human ASF1a–HIRA complex and insights into specificity of histone chaperone complex assembly8.8182Citations (PDF)
89Sequence comparison and protein structure prediction6.4174Citations (PDF)
90ProtBuD: a database of biological unit structures of protein families and superfamilies
Bioinformatics, 2006, 22, 2876-2882
4.746Citations (PDF)
91Regulation of the Oxidative Stress Response Through Slt2p-Dependent Destruction of Cyclin C in Saccharomyces cerevisiae
Genetics, 2006, 172, 1477-1486
4.259Citations (PDF)
92Domain definition and target classification for CASP62.626Citations (PDF)
93Assessment of fold recognition predictions in CASP62.651Citations (PDF)
94Assessment of disorder predictions in CASP62.6107Citations (PDF)
95MollDE: a homology modeling framework you can click with
Bioinformatics, 2005, 21, 2914-2916
4.747Citations (PDF)
96PISCES: recent improvements to a PDB sequence culling server
Nucleic Acids Research, 2005, 33, W94-W98
15.5325Citations (PDF)
97Quasi-consensus-based comparison of profile hidden Markov models for protein sequences
Bioinformatics, 2005, 21, 2287-2293
4.717Citations (PDF)
98Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA
Developmental Cell, 2005, 8, 19-30
7.7652Citations (PDF)
99Scoring profile-to-profile sequence alignments
Protein Science, 2004, 13, 1612-1626
5.9130Citations (PDF)
100CAFASP3: The third critical assessment of fully automated structure prediction methods2.6110Citations (PDF)
101Cyclic coordinate descent: A robotics algorithm for protein loop closure
Protein Science, 2003, 12, 963-972
5.9496Citations (PDF)
102A graph‐theory algorithm for rapid protein side‐chain prediction
Protein Science, 2003, 12, 2001-2014
5.9929Citations (PDF)
103PISCES: a protein sequence culling server
Bioinformatics, 2003, 19, 1589-1591
4.71,623Citations (PDF)
104A Structural Basis for Half-of-the-sites Metal Binding Revealed in Drosophila melanogaster Porphobilinogen Synthase
Journal of Biological Chemistry, 2003, 278, 31325-31330
2.215Citations (PDF)
105BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster
Bioinformatics, 2002, 18, 765-766
4.737Citations (PDF)
106Mapping the Epitope of an Inhibitory Monoclonal Antibody to the C-terminal DNA-binding Domain of HIV-1 Integrase
Journal of Biological Chemistry, 2002, 277, 12164-12174
2.220Citations (PDF)
107CASA: a server for the critical assessment of protein sequence alignment accuracy
Bioinformatics, 2002, 18, 496-497
4.711Citations (PDF)
108Identification and Characterization of a Paralog of Human Cell Cycle Checkpoint Gene HUS1
Genomics, 2002, 79, 487-492
2.830Citations (PDF)
109Rotamer Libraries in the 21st Century6.4646Citations (PDF)
110OVCA2 is downregulated and degraded during retinoid-induced apoptosis4.325Citations (PDF)
111CAFASP2: The second critical assessment of fully automated structure prediction methods2.6132Citations (PDF)
112The Molecular Mechanism of Lead Inhibition of Human Porphobilinogen Synthase
Journal of Biological Chemistry, 2001, 276, 1531-1537
2.2108Citations (PDF)
113Mutations in the regulatory domain of cystathionine beta-synthase can functionally suppress patient-derived mutations in cis
Human Molecular Genetics, 2001, 10, 635-643
2.9106Citations (PDF)
114Large-scale comparison of protein sequence alignment algorithms with structure alignments
2000, 40, 6-22
227Citations (PDF)
115Identification of a novel pre-TCR isoform in which the accessibility of the TCRβ subunit is determined by occupancy of the `missing' V domain of pre-Tα
International Immunology, 2000, 12, 1579-1591
3.14Citations (PDF)
116An Inhibitory Monoclonal Antibody Binds at the Turn of the Helix-Turn-Helix Motif in the N-terminal Domain of HIV-1 Integrase
Journal of Biological Chemistry, 2000, 275, 38739-38748
2.225Citations (PDF)
117An Artificial Gene for Human Porphobilinogen Synthase Allows Comparison of an Allelic Variation Implicated in Susceptibility to Lead Poisoning
Journal of Biological Chemistry, 2000, 275, 2619-2626
2.242Citations (PDF)
118Identification and Structural Analysis of Human RBM8A and RBM8B: Two Highly Conserved RNA-Binding Motif Proteins That Interact with OVCA1, a Candidate Tumor Suppressor
Genomics, 2000, 69, 54-62
2.852Citations (PDF)
119Modeling of substrate specificity of the Alzheimer’s disease amyloid precursor protein β-secretase 1 1Edited by F. E. Cohen
Journal of Molecular Biology, 2000, 300, 241-248
4.153Citations (PDF)
120Porphobilinogen Synthase from Pea:  Expression from an Artificial Gene, Kinetic Characterization, and Novel Implications for Subunit Interactions†
Biochemistry, 2000, 39, 9018-9029
2.446Citations (PDF)
121The evolutionarily conserved Dim1 protein defines a novel branch of the thioredoxin fold superfamily
Physiological Genomics, 1999, 1, 109-118
2.426Citations (PDF)
122Ier5,a Novel Member of the Slow-Kinetics Immediate-Early Genes
Genomics, 1999, 55, 327-334
2.854Citations (PDF)
123Unique Properties of the Large Antigen of Hepatitis Delta Virus
Journal of Virology, 1999, 73, 7147-7152
3.613Citations (PDF)
124Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool
Journal of Molecular Biology, 1997, 267, 1268-1282
4.1545Citations (PDF)
125Meeting review: the Second Meeting on the Critical Assessment of Techniques for Protein Structure Prediction (CASP2), Asilomar, California, December 13–16, 1996
Folding & Design, 1997, 2, R27-R42
4.250Citations (PDF)
126Entamoeba histolytica:Computer-Assisted Modeling of Phosphofructokinase for the Prediction of Broad-Spectrum Antiparasitic Agents
Experimental Parasitology, 1997, 87, 194-202
1.422Citations (PDF)
127Bayesian statistical analysis of protein side‐chain rotamer preferences
Protein Science, 1997, 6, 1661-1681
5.9750Citations (PDF)
128Conformational analysis of the backbone-dependent rotamer preferences of protein sidechains8.8325Citations (PDF)
129Cis-Trans Imide Isomerization of the Proline Dipeptide15.0212Citations (PDF)
130Backbone-dependent Rotamer Library for Proteins Application to Side-chain Prediction
Journal of Molecular Biology, 1993, 230, 543-574
4.1916Citations (PDF)
131Molecular dynamics simulation of the proline conformational equilibrium and dynamics in antamanide using the CHARMM force field15.064Citations (PDF)
132Mutational Analysis of the Structure and Function of the CD4 Protein
Immunological Reviews, 1989, 109, 17-37
6.415Citations (PDF)
133Calculation of Franck-Condon factors for undergraduate quantum chemistry2.816Citations (PDF)
134PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107
ELife, 0, 10,
0.735Citations (PDF)
135BPS2026 – Interfamily crosstalk between ERK2, RSK2, and mTORC2 across four kinase families
Biophysical Journal, 0, 125, 151a-152a
2.20Citations (PDF)
136Defining active conformations from substrate-bound structures enables active-state AlphaFold2 modeling of all 437 human catalytic protein kinase domains
Biochemical Journal, 0, 483, 1281-1317
3.80Citations (PDF)