| 1 | Subunit disassembly and inhibition of TNFα by a semi-synthetic bicyclic peptide | 2.6 | 39 | Citations (PDF) |
| 2 | Encoded libraries of chemically modified peptides | 5.8 | 119 | Citations (PDF) |
| 3 | Characterization of a major sporozoite surface glycoprotein of Cryptosporidum parvum | 2.9 | 21 | Citations (PDF) |
| 4 | Bicyclic Peptide Inhibitor Reveals Large Contact Interface with a Protease Target | 3.7 | 176 | Citations (PDF) |
| 5 | Bicyclic Peptides with Optimized Ring Size Inhibit Human Plasma Kallikrein and its Orthologues While Sparing Paralogous Proteases | 3.1 | 69 | Citations (PDF) |
| 6 | Phage-encoded combinatorial chemical libraries based on bicyclic peptides | 11.8 | 721 | Citations (PDF) |
| 7 | Thermodynamically Stable Aggregation-Resistant Antibody Domains through Directed Evolution | 4.1 | 118 | Citations (PDF) |
| 8 | β-Edge Interactions in a Pentadecameric Human Antibody Vκ Domain | 4.1 | 14 | Citations (PDF) |
| 9 | Repertoires of aggregation-resistant human antibody domains | 2.6 | 85 | Citations (PDF) |
| 10 | Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting | 4.1 | 74 | Citations (PDF) |
| 11 | Identification of Protein Domains by Shotgun Proteolysis | 4.1 | 23 | Citations (PDF) |
| 12 | Early Protein Evolution: Building Domains from Ligand-binding Polypeptide Segments | 4.1 | 39 | Citations (PDF) |
| 13 | Tapping diversity lost in transformations—in vitro amplification of ligation reactions | 15.5 | 29 | Citations (PDF) |
| 14 | Engineering aggregation-resistant proteins by directed evolution | 2.6 | 14 | Citations (PDF) |
| 15 | Mapping epitopes and antigenicity by site-directed masking | 7.5 | 37 | Citations (PDF) |
| 16 | Generating molecular diversity by homologous recombination in Escherichia coli | 2.6 | 11 | Citations (PDF) |
| 17 | Selection of optical biosensors from chemisynthetic antibody libraries | 2.6 | 33 | Citations (PDF) |
| 18 | A native-like artificial protein from antisense DNA | 2.6 | 16 | Citations (PDF) |
| 19 | Aggregation-resistant domain antibodies selected on phage by heat denaturation | 29.8 | 262 | Citations (PDF) |
| 20 | Stabilization of antibody VH-domains by proteolytic selection | 2.2 | 10 | Citations (PDF) |
| 21 | Crystal Structure of HEL4, a Soluble, Refoldable Human VH Single Domain with a Germ-line Scaffold | 4.1 | 144 | Citations (PDF) |
| 22 | Stabilization of antibody VH-domains by proteolytic selection | 2.2 | 0 | Citations (PDF) |
| 23 | Identification of functional similarities between proteins using directed evolution | 7.5 | 12 | Citations (PDF) |
| 24 | Selection of large diversities of antiidiotypic antibody fragments by phage display | 4.1 | 136 | Citations (PDF) |
| 25 | Single-chain antibody-based gene therapy: inhibition of tumor growth by in situ production of phage-derived human antibody fragments blocking functionally active sites of cell-associated matrices | 3.5 | 48 | Citations (PDF) |
| 26 | Improving the display of proteins on filamentous phage | 3.0 | 43 | Citations (PDF) |
| 27 | Molecular Characterization of Human Monoclonal Antibodies Derived from Fusions of Tonsil Lymphocytes with a Human Myeloma Cell Line | 0.7 | 7 | Citations (PDF) |
| 28 | Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG+ B cells | 3.1 | 44 | Citations (PDF) |
| 29 | Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor | 1.4 | 32 | Citations (PDF) |
| 30 | Novel folded protein domains generated by combinatorial shuffling of polypeptide segments | 7.5 | 95 | Citations (PDF) |
| 31 | Eine Methode zur Selektion katalytischer Aktivität, die Phagendisplay und Nachbarschaftseffekte nutzt | 1.4 | 14 | Citations (PDF) |
| 32 | A Method for the Selection of Catalytic Activity Using Phage Display and Proximity Coupling | 14.4 | 87 | Citations (PDF) |
| 33 | Interdomain interactions within the gene 3 protein of filamentous phage | 2.7 | 16 | Citations (PDF) |
| 34 | Identification of a Glioblastoma-Associated Tenascin-C Isoform by a High Affinity Recombinant Antibody | 3.4 | 111 | Citations (PDF) |
| 35 | A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn | 4.1 | 108 | Citations (PDF) |
| 36 | Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vλ repertoire | 4.1 | 19 | Citations (PDF) |
| 37 | Somatic insertions and deletions shape the human antibody repertoire 1 1Edited by J. Karn | 4.1 | 80 | Citations (PDF) |
| 38 | Proteolytic selection for protein folding using filamentous bacteriophages | 4.2 | 251 | Citations (PDF) |
| 39 | Making antibody and peptide ligands by repertoire selection technologies 1998, 11, 126-127 | | 6 | Citations (PDF) |
| 40 | Synthetic human antibodies and a strategy for protein engineering | 2.7 | 41 | Citations (PDF) |
| 41 | Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage | 4.1 | 102 | Citations (PDF) |
| 42 | Expression of an antibody fragment at high levels in the bacterial cytoplasm | 4.1 | 212 | Citations (PDF) |
| 43 | Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6 | 2.2 | 26 | Citations (PDF) |
| 44 | Improved tumour targeting by disulphide stabilized diabodies expressed in Pichia pastoris | 2.6 | 85 | Citations (PDF) |
| 45 | The creation of diversity in the human immunoglobulin Vλ repertoire | 4.1 | 143 | Citations (PDF) |
| 46 | Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, “minor” D segments or D-D recombination 1 1Edited By J. Karn | 4.1 | 290 | Citations (PDF) |
| 47 | Enzyme immunoassays using bispecific diabodies | 1.1 | 53 | Citations (PDF) |
| 48 | Complement recruitment using bispecific diabodies | 29.8 | 61 | Citations (PDF) |
| 49 | Retargeting serum immunoglobulin with bispecific diabodies | 29.8 | 78 | Citations (PDF) |
| 50 | Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform | 29.8 | 284 | Citations (PDF) |
| 51 | Characterization of Events during the Late Stages of HPV16 Infectionin VivoUsing High-Affinity Synthetic Fabs to E4 | 2.3 | 132 | Citations (PDF) |
| 52 | Diabodies: small bispecific antibody fragments | 4.6 | 39 | Citations (PDF) |
| 53 | Analysis of VH/VL combinations in single peripheral IgG-producing B cells in the normal and autoimmune repertoire | 2.4 | 0 | Citations (PDF) |
| 54 | Dimerization of Fab fragments enables ready screening of phage antibodies that affect hepatocyte growth factor/scatter factor activity on target cells | 3.1 | 10 | Citations (PDF) |
| 55 | Immunoglobulin lambda light chain orphons on human chromosome 8q11.2 | 3.1 | 29 | Citations (PDF) |
| 56 | Phage antibodies against an unstable hapten: Oxygen sensitive reduced flavin | 2.7 | 16 | Citations (PDF) |
| 57 | Mimicking Somatic Hypermutation: Affinity Maturation of Antibodies Displayed on Bacteriophage Using a Bacterial Mutator Strain | 4.1 | 217 | Citations (PDF) |
| 58 | Sequence and Evolution of the Human Germline VλRepertoire | 4.1 | 207 | Citations (PDF) |
| 59 | Phage antibodies with pan-species recognition of the oncofoetal angiogenesis marker fibronectin ED-B domain | 4.3 | 146 | Citations (PDF) |
| 60 | Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP | 29.8 | 42 | Citations (PDF) |
| 61 | Open sandwich ELISA: A novel immunoassay based on the interchain interaction of antibody variable region | 29.8 | 169 | Citations (PDF) |
| 62 | Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody | 2.6 | 82 | Citations (PDF) |
| 63 | A strategy of exon shuffling for making large peptide repertoires displayed on filamentous bacteriophage. | 7.5 | 55 | Citations (PDF) |
| 64 | Calmodulin as a Versatile Tag for Antibody Fragments | 29.8 | 45 | Citations (PDF) |
| 65 | Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2 | 2.9 | 140 | Citations (PDF) |
| 66 | An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection | 2.2 | 27 | Citations (PDF) |
| 67 | A Complete Map of the Human Immunoglobulin VH Locus | 4.0 | 25 | Citations (PDF) |
| 68 | Comparison of the Human Germline and Rearranged VH Repertoire Reveals Complementarity between Germline Variability and Somatic Mutation | 4.0 | 4 | Citations (PDF) |
| 69 | Human immunoglobulin V H and D segments on chromosomes 15q11.2 and 16p11.2 | 2.9 | 77 | Citations (PDF) |
| 70 | A directory of human germ-line Vχ segments reveals a strong bias in their usage | 3.1 | 229 | Citations (PDF) |
| 71 | Making Antibodies by Phage Display Technology | 29.4 | 1,569 | Citations (PDF) |
| 72 | Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen | 29.8 | 186 | Citations (PDF) |
| 73 | A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q | 25.2 | 252 | Citations (PDF) |
| 74 | Crystal structure of a diabody, a bivalent antibody fragment | 3.8 | 192 | Citations (PDF) |
| 75 | Selection of β-Lactamase on Filamentous Bacteriophage by Catalytic Activity | 4.1 | 134 | Citations (PDF) |
| 76 | In Vitro Assembly of Repertoires of Antibody Chains on the Surface of Phage by Renaturation | 4.1 | 76 | Citations (PDF) |
| 77 | Isolation of a Peptide Antagonist to the Thrombin Receptor using Phage Display | 4.1 | 97 | Citations (PDF) |
| 78 | Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents. | 7.3 | 511 | Citations (PDF) |
| 79 | Cloning and sequencing of human immunoglobulinλ. gene segments | 3.1 | 155 | Citations (PDF) |
| 80 | Humanized antibodies | 6.9 | 147 | Citations (PDF) |
| 81 | Engineering bispecific antibodies | 6.8 | 78 | Citations (PDF) |
| 82 | Human Antibody Fragments Specific for Human Blood Group Antigens from a Phage Display Library | 29.8 | 183 | Citations (PDF) |
| 83 | The Contribution of Contact and Non-contact Residues of Antibody in the Affinity of Binding to Antigen | 4.1 | 149 | Citations (PDF) |
| 84 | Combinatorial infection andin vivorecombination: a strategy for making large phage antibody repertoires | 15.5 | 170 | Citations (PDF) |
| 85 | Building antibodies from their genes | 0.4 | 3 | Citations (PDF) |
| 86 | Humanized antibodies | 11.4 | 64 | Citations (PDF) |
| 87 | Retroviral vectors displaying functional antibody fragments | 15.5 | 227 | Citations (PDF) |
| 88 | HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VHlocus | 15.5 | 39 | Citations (PDF) |
| 89 | "Diabodies": small bivalent and bispecific antibody fragments. | 7.5 | 879 | Citations (PDF) |
| 90 | In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells | 15.5 | 150 | Citations (PDF) |
| 91 | By–Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling | 29.8 | 331 | Citations (PDF) |
| 92 | Blood clearance in the rat of a recombinant mouse monoclonal antibody lacking the N-linked oligosaccharide side chains of the CH2 domains | 2.2 | 57 | Citations (PDF) |
| 93 | Recombinant mouse monoclonal antibodies with single amino acid substitutions affecting C1q and high affinity Fc receptor binding have identical serum half-lives in the BALB/c mouse | 2.2 | 25 | Citations (PDF) |
| 94 | Multiple binding sites on the CH2 domain of IgG for mouse FcγR11 | 2.2 | 61 | Citations (PDF) |
| 95 | The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops | 4.1 | 659 | Citations (PDF) |
| 96 | Structural repertoire of the human VH segments | 4.1 | 416 | Citations (PDF) |
| 97 | Selection of phage antibodies by binding affinity | 4.1 | 553 | Citations (PDF) |
| 98 | By-passing immunisation | 4.1 | 446 | Citations (PDF) |
| 99 | Antibody framework residues affecting the conformation of the hypervariable loops | 4.1 | 568 | Citations (PDF) |
| 100 | Building Antibodies from their Genes | 6.4 | 146 | Citations (PDF) |
| 101 | Cell selection strategies for making antibodies from variable gene libraries: trapping the memory pool | 3.1 | 56 | Citations (PDF) |
| 102 | Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system. | 2.2 | 181 | Citations (PDF) |
| 103 | Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift. | 10.6 | 98 | Citations (PDF) |
| 104 | Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains | 15.5 | 1,050 | Citations (PDF) |
| 105 | By-passing immunization | 4.1 | 1,652 | Citations (PDF) |
| 106 | Purification and characterization of a membrane-bound acid phosphatase of Leishmania mexicana | 1.3 | 59 | Citations (PDF) |
| 107 | Man-made antibodies | 37.9 | 988 | Citations (PDF) |
| 108 | Making antibody fragments using phage display libraries | 37.9 | 1,214 | Citations (PDF) |
| 109 | Filter screening of antibody Fab fragments secreted from individual bacterial colonies: Specific detection of antigen binding with a two-membrane system | 2.4 | 53 | Citations (PDF) |
| 110 | Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes | 3.1 | 230 | Citations (PDF) |
| 111 | Phage antibodies: filamentous phage displaying antibody variable domains | 37.9 | 2,386 | Citations (PDF) |
| 112 | Symposium 12: New molecular biology techniques in clinical biochemistry | 0.7 | 0 | Citations (PDF) |
| 113 | Crystallization and preliminary X-ray diffraction study of the bacterially expressed Fv from the monoclonal anti-lysozyme antibody D1.3 and of its complex with the antigen, lysozyme | 4.1 | 61 | Citations (PDF) |
| 114 | ‘Sticky feet’-directed mutagenesis and its application to swapping antibody domains | 15.5 | 68 | Citations (PDF) |
| 115 | Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli | 37.9 | 1,058 | Citations (PDF) |
| 116 | Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. | 7.5 | 669 | Citations (PDF) |
| 117 | Secretion of a homodimeric V±CΚ T-cell receptor-immunoglobulin chimeric protein | 2.2 | 26 | Citations (PDF) |
| 118 | Generating Binding Activities from Escherichia coli by Expression of a Repertoire of Immunoglobulin Variable Domains | 1.6 | 14 | Citations (PDF) |
| 119 | Reshaping human antibodies for therapy | 37.9 | 1,582 | Citations (PDF) |
| 120 | Localization of the binding site for the human high-affinity Fc receptor on IgG | 37.9 | 288 | Citations (PDF) |
| 121 | The binding site for C1q on IgG | 37.9 | 589 | Citations (PDF) |
| 122 | Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism | 2.4 | 174 | Citations (PDF) |
| 123 | Expression of an antibody Fv fragment in myeloma cells | 4.1 | 105 | Citations (PDF) |
| 124 | REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H | 62.1 | 526 | Citations (PDF) |
| 125 | Structure-activity relationships in engineered proteins: characterization of disruptive deletions in the .alpha.-ammonium group binding site of tyrosyl-tRNA synthetase | 2.4 | 26 | Citations (PDF) |
| 126 | A model of synthetase/transfer RNA interaction as deduced by protein engineering | 37.9 | 128 | Citations (PDF) |
| 127 | Reduced heat resistance of mutant spores after cloning and mutagenesis of the Bacillus subtilis gene encoding penicillin-binding protein 5 | 2.9 | 67 | Citations (PDF) |
| 128 | Protein engineering of tyrosyl-tRNA synthetase: the charging of tRNA | 1.0 | 3 | Citations (PDF) |
| 129 | Construction of heterodimer tyrosyl-tRNA synthetase shows tRNATyr interacts with both subunits. | 7.5 | 69 | Citations (PDF) |
| 130 | Sexist ads | 37.9 | 1 | Citations (PDF) |
| 131 | Replacing the complementarity-determining regions in a human antibody with those from a mouse | 37.9 | 1,392 | Citations (PDF) |
| 132 | A transcription terminator in the 5' non-coding region of the tyrosyl tRNA synthetase gene from Bacillus stearothermophilus | 0.2 | 15 | Citations (PDF) |
| 133 | Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering. | 7.5 | 180 | Citations (PDF) |
| 134 | Hydrogen bonding and biological specificity analysed by protein engineering | 37.9 | 1,172 | Citations (PDF) |
| 135 | EcoK selection vectors for shotgun cloning into M13 and deletion mutagenesls | 15.5 | 51 | Citations (PDF) |
| 136 | Improved oligonudeotide site-directed rautagenesis using M13 vectors | 15.5 | 566 | Citations (PDF) |
| 137 | Engineering of tyrosyl tRNA synthetase | 2.9 | 2 | Citations (PDF) |
| 138 | Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface | 2.4 | 63 | Citations (PDF) |
| 139 | Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase | 2.4 | 43 | Citations (PDF) |
| 140 | Probing histidine-substrate interactions in tyrosyl-tRNA synthetase using asparagine and glutamine replacements | 2.4 | 95 | Citations (PDF) |
| 141 | Engineering enzymes | 8.7 | 21 | Citations (PDF) |
| 142 | A large increase in enzyme–substrate affinity by protein engineering | 37.9 | 156 | Citations (PDF) |
| 143 | The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus) | 33.6 | 622 | Citations (PDF) |
| 144 | The Amino Acid Sequence of the Tyrosy1-tRNA Synthetase from Bacillus stearothermophilus | 0.2 | 113 | Citations (PDF) |
| 145 | Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation | 2.4 | 297 | Citations (PDF) |
| 146 | Does the higher order structure of the influenza virus ribonucleoprotein guide sequence rearrangements in influenza viral RNA? | 33.6 | 213 | Citations (PDF) |
| 147 | Deletion mutagenesis using an ‘M13 splint’: the N-terminal structural domain of tyrosyl-tRNA synthetase (B. stearothermophilus) catalyses the formation of tyrosyl adenylate. | 7.3 | 79 | Citations (PDF) |
| 148 | Nucteotide sequence of human influenza A/PR/8/34 segment 2 | 15.5 | 62 | Citations (PDF) |
| 149 | Nucleotide sequences of influenza virus segments 1 and 3 reveal mosaic structure of a small viral RNA segment | 33.6 | 172 | Citations (PDF) |
| 150 | Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding | 37.9 | 352 | Citations (PDF) |
| 151 | The structure of the gene encoding the nucleoprotein of human influenza virus A/PR/8/34 | 2.3 | 116 | Citations (PDF) |
| 152 | The use of synthetic oligodeoxynucleotide primers in cloning and sequencing segment 8 of influenza virus (A/PR/8/34) | 15.5 | 113 | Citations (PDF) |
| 153 | Nucleotide-sequence heterogeneity and sequence rearrangements in influenza virus cDNA | 2.3 | 84 | Citations (PDF) |
| 154 | Structure of the neuraminidase gene in human influenza virus A/PR/8/34 | 37.9 | 233 | Citations (PDF) |
| 155 | Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype | 37.9 | 240 | Citations (PDF) |
| 156 | The structure of two subgenomic RNAs from human infhienza virus A/PR/8/34 | 15.5 | 38 | Citations (PDF) |
| 157 | Cloning of influenza cDNA into M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein | 15.5 | 271 | Citations (PDF) |
| 158 | 3′ End labelling of RNA with32P suitable for rapid gel sequencing | 15.5 | 42 | Citations (PDF) |
