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247 peer-reviewed articles • 62,607 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
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1Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease
Nature, 2025, 641, 718-731
37.960Citations (PDF)
2Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense
Science, 2025, 389, 260-267
36.327Citations (PDF)
3Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt
Nature Immunology, 2025, 26, 1527-1539
23.512Citations (PDF)
4LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation
Immunity, 2024, 57, 206-222
22.6230Citations (PDF)
5Beyond T cell exhaustion: TIM-3 regulation of myeloid cells13.460Citations (PDF)
6Autoimmunity and the microbiome
Immunological Reviews, 2024, 325, 4-8
6.44Citations (PDF)
7BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells
Nature Immunology, 2024, 25, 1395-1410
23.540Citations (PDF)
8Neuropeptide signalling orchestrates T cell differentiation
Nature, 2024, 635, 444-452
37.961Citations (PDF)
9TH17 cell heterogeneity and its role in tissue inflammation
Nature Immunology, 2023, 24, 19-29
23.5259Citations (PDF)
10Immune Checkpoint Molecule TIGIT Regulates Kidney T Cell Functions and Contributes to AKI0.428Citations (PDF)
11Droplet-based forward genetic screening of astrocyte–microglia cross-talk
Science, 2023, 379, 1023-1030
36.3114Citations (PDF)
12B-cell-specific checkpoint molecules that regulate anti-tumour immunity
Nature, 2023, 619, 348-356
37.9161Citations (PDF)
13Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells
Nature, 2023, 620, 881-889
37.9172Citations (PDF)
14Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation
Nature Immunology, 2023, 24, 1908-1920
23.537Citations (PDF)
15Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function
Immunity, 2022, 55, 159-173.e9
22.6155Citations (PDF)
16Systems-based approaches to study immunometabolism12.657Citations (PDF)
17Activation pathways that drive CD4+ T cells to break tolerance in autoimmune diseases*
Immunological Reviews, 2022, 307, 161-190
6.442Citations (PDF)
18B Cell IL-4 Drives Th2 Responses In Vivo, Ameliorates Allograft Rejection, and Promotes Allergic Airway Disease4.912Citations (PDF)
19Tim-3 adapter protein Bat3 acts as an endogenous regulator of tolerogenic dendritic cell function13.448Citations (PDF)
20Tim-3 mediates T cell trogocytosis to limit antitumor immunity10.668Citations (PDF)
21Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis7.572Citations (PDF)
22Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function6.910Citations (PDF)
23Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
Cell Stem Cell, 2022, 29, 760-775.e10
16.480Citations (PDF)
24Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis
Atherosclerosis, 2022, 352, 1-9
1.55Citations (PDF)
25Metabolic regulation and function of T helper cells in neuroinflammation
Seminars in Immunopathology, 2022, 44, 581-598
8.126Citations (PDF)
26Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion
Science Advances, 2021, 7,
10.937Citations (PDF)
27KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
Cell Metabolism, 2021, 33, 1042-1061.e7
25.2265Citations (PDF)
28TIM-3 restrains anti-tumour immunity by regulating inflammasome activation
Nature, 2021, 595, 101-106
37.9351Citations (PDF)
29Foxo1 controls gut homeostasis and commensalism by regulating mucus secretion9.362Citations (PDF)
30Metabolic modeling of single Th17 cells reveals regulators of autoimmunity
Cell, 2021, 184, 4168-4185.e21
33.6491Citations (PDF)
31Polyamine metabolism is a central determinant of helper T cell lineage fidelity
Cell, 2021, 184, 4186-4202.e20
33.6288Citations (PDF)
32Spatially organized multicellular immune hubs in human colorectal cancer
Cell, 2021, 184, 4734-4752.e20
33.6788Citations (PDF)
33Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity
Cell, 2021, 184, 6281-6298.e23
33.6251Citations (PDF)
34Cytokines and transcription factors in the differentiation of CD4+ T helper cell subsets and induction of tissue inflammation and autoimmunity5.281Citations (PDF)
35Aberrant expression of USF2 in refractory rheumatoid arthritis and its regulation of proinflammatory cytokines in Th17 cells7.537Citations (PDF)
36An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets
Cell Reports, 2020, 33, 108433
6.385Citations (PDF)
37Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
Immunity, 2020, 53, 658-671.e6
22.6225Citations (PDF)
38The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
Cell Research, 2020, 30, 285-299
12.4197Citations (PDF)
39Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses
Immunity, 2019, 51, 709-723.e6
22.6246Citations (PDF)
40Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses
Immunity, 2019, 51, 696-708.e9
22.6268Citations (PDF)
41Tim-3: A co-receptor with diverse roles in T cell exhaustion and tolerance
Seminars in Immunology, 2019, 42, 101302
6.7142Citations (PDF)
42Epigenetic and transcriptional mechanisms for the regulation of IL-10
Seminars in Immunology, 2019, 44, 101324
6.756Citations (PDF)
43Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells
Immunity, 2019, 50, 181-194.e6
22.6603Citations (PDF)
44TIM3 comes of age as an inhibitory receptor
Nature Reviews Immunology, 2019, 20, 173-185
53.8881Citations (PDF)
45Podoplanin is a negative regulator of Th17 inflammation
JCI Insight, 2019, 2,
5.432Citations (PDF)
46SGK1 Governs the Reciprocal Development of Th17 and Regulatory T Cells
Cell Reports, 2018, 22, 653-665
6.3100Citations (PDF)
47Modeling tumor immunity of mouse glioblastoma by exhausted CD8+ T cells3.427Citations (PDF)
48Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content
Cardiovascular Research, 2018, 114, 158-167
5.581Citations (PDF)
49Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
Immunity, 2018, 48, 556-569.e7
22.680Citations (PDF)
50High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-33.450Citations (PDF)
51Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation
Immunological Reviews, 2018, 286, 53-73
6.455Citations (PDF)
52T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation
Cell, 2018, 175, 1307-1320.e22
33.6587Citations (PDF)
53An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells
Nature Immunology, 2018, 19, 1126-1136
23.593Citations (PDF)
54Induction and transcriptional regulation of the co-inhibitory gene module in T cells
Nature, 2018, 558, 454-459
37.9440Citations (PDF)
55The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program
Nature Immunology, 2017, 18, 344-353
23.556Citations (PDF)
56Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation
Nature Immunology, 2017, 18, 412-421
23.5122Citations (PDF)
57Tim‐3 and its role in regulating anti‐tumor immunity
Immunological Reviews, 2017, 276, 97-111
6.4790Citations (PDF)
58Phagocytosis imprints heterogeneity in tissue-resident macrophages
Journal of Experimental Medicine, 2017, 214, 1281-1296
9.3278Citations (PDF)
59Targeting latency-associated peptide promotes antitumor immunity13.474Citations (PDF)
60The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation
Nature, 2017, 549, 351-356
37.9626Citations (PDF)
61Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis13.7130Citations (PDF)
62IL-17 Blockade in Psoriasis
Cell, 2016, 167, 1669
33.656Citations (PDF)
63Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
Immunity, 2016, 44, 989-1004
22.62,017Citations (PDF)
64A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells
Cell, 2016, 166, 1500-1511.e9
33.6405Citations (PDF)
65RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression
Cell Reports, 2016, 16, 392-404
6.3107Citations (PDF)
66Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity
Journal of Experimental Medicine, 2016, 213, 2489-2501
9.363Citations (PDF)
67IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization
Journal of Experimental Medicine, 2016, 213, 2147-2166
9.397Citations (PDF)
68TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection
PLoS Pathogens, 2016, 12, e1005490
4.4204Citations (PDF)
69Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells
Journal of Clinical Investigation, 2015, 125, 4212-4222
10.6322Citations (PDF)
70TIGIT predominantly regulates the immune response via regulatory T cells
Journal of Clinical Investigation, 2015, 125, 4053-4062
10.6545Citations (PDF)
71Pathogenic Transdifferentiation of Th17 Cells Contribute to Perpetuation of Rheumatoid Arthritis during Anti-TNF Treatment
Molecular Medicine, 2015, 21, 536-543
5.628Citations (PDF)
72A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation
Journal of Autoimmunity, 2015, 59, 38-42
6.69Citations (PDF)
73Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity
Journal of Clinical Investigation, 2015, 125, 2211-2219
10.6220Citations (PDF)
74Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions
Immunity, 2015, 43, 1040-1051
22.6482Citations (PDF)
75Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury
Journal of Hepatology, 2015, 62, 563-572
4.258Citations (PDF)
76An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction13.7204Citations (PDF)
77Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation
Journal of Immunology, 2015, 194, 1602-1608
0.6133Citations (PDF)
78Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation
Neuron, 2015, 87, 341-354
11.0429Citations (PDF)
79Oct1 and OCA-B are selectively required for CD4 memory T cell function
Journal of Experimental Medicine, 2015, 212, 2115-2131
9.359Citations (PDF)
80Effector T cell differentiation: are master regulators of effector T cells still the masters?5.264Citations (PDF)
81Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses
Cell, 2015, 162, 1338-1352
33.6285Citations (PDF)
82CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
Cell, 2015, 163, 1413-1427
33.6387Citations (PDF)
83Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity
Cell, 2015, 163, 1400-1412
33.6581Citations (PDF)
84Podoplanin negatively regulates CD4+ effector T cell responses10.644Citations (PDF)
85KIM-1–mediated phagocytosis reduces acute injury to the kidney
Journal of Clinical Investigation, 2015, 125, 1620-1636
10.6341Citations (PDF)
86IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis
Journal of Clinical Investigation, 2015, 125, 4011-4020
10.637Citations (PDF)
87Defining the functional states of Th17 cells
F1000Research, 2015, 4, 132
0.529Citations (PDF)
88The Dichotomous Pattern of IL-12R and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation
PLoS ONE, 2014, 9, e89092
2.340Citations (PDF)
89Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response2.428Citations (PDF)
90Coinhibitory receptors and CD8 T cell exhaustion in chronic infections3.371Citations (PDF)
91Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
Immunity, 2014, 40, 569-581
22.6917Citations (PDF)
92TIM-1 Glycoprotein Binds the Adhesion Receptor P-Selectin and Mediates T Cell Trafficking during Inflammation and Autoimmunity
Immunity, 2014, 40, 542-553
22.676Citations (PDF)
93Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread
Nature, 2014, 509, 230-234
37.9149Citations (PDF)
94Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells
Immunity, 2014, 41, 270-282
22.6343Citations (PDF)
95Unexpected Targets and Triggers of Autoimmunity3.113Citations (PDF)
96Comment on “Tim-3 Directly Enhances CD8 T Cell Responses to Acute Listeria monocytogenes Infection”
Journal of Immunology, 2014, 193, 467-467
0.65Citations (PDF)
97Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms
Immunity, 2014, 40, 477-489
22.6282Citations (PDF)
98Reversal of NK-Cell Exhaustion in Advanced Melanoma by Tim-3 Blockade
Cancer Immunology Research, 2014, 2, 410-422
4.2394Citations (PDF)
99P-171 Serum and Glucocorticoid-Regulated Kinase 1 (SGK-1) Is Associated with Intestinal Inflammation by Regulating IL-23 Receptor Function on T Cells2.90Citations (PDF)
100T‐cell immunoglobulin and mucin domain 4 (TIM‐4) signaling in innate immune‐mediated liver ischemia‐reperfusion injury
Hepatology, 2014, 60, 2052-2064
10.175Citations (PDF)
101CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
Nature, 2014, 517, 386-390
37.9679Citations (PDF)
102Genetic and epigenetic fine mapping of causal autoimmune disease variants
Nature, 2014, 518, 337-343
37.91,972Citations (PDF)
103Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells
Journal of Clinical Investigation, 2014, 124, 2513-2522
10.642Citations (PDF)
104Fragile TIM-4–expressing tissue resident macrophages are migratory and immunoregulatory
Journal of Clinical Investigation, 2014, 124, 3443-3454
10.671Citations (PDF)
105TGF-β Signaling Initiated in Dendritic Cells Instructs Suppressive Effects on Th17 Differentiation at the Site of Neuroinflammation
PLoS ONE, 2014, 9, e102390
2.326Citations (PDF)
106Using EAE to better understand principles of immune function and autoimmune pathology
Journal of Autoimmunity, 2013, 45, 31-39
6.6233Citations (PDF)
107Dynamic regulatory network controlling TH17 cell differentiation
Nature, 2013, 496, 461-468
37.9674Citations (PDF)
108Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
Nature, 2013, 496, 513-517
37.9975Citations (PDF)
109Brief Report: Increased expression of a short splice variant of CTLA‐4 exacerbates lupus in MRL/lpr mice
Arthritis and Rheumatism, 2013, 65, 764-769
6.111Citations (PDF)
110MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling7.585Citations (PDF)
111TIM3+FOXP3+regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer
OncoImmunology, 2013, 2, e23849
5.4309Citations (PDF)
112Aiolos Silences Il2 Expression and Promotes Th17 Cell Differentiation (S50.002)
Neurology, 2013, 80,
1.00Citations (PDF)
113Anti-Ro52 monoclonal antibodies specific for amino acid 200–239, but not other Ro52 epitopes, induce congenital heart block in a rat model6.948Citations (PDF)
114TIM Family Proteins Promote the Lysosomal Degradation of the Nuclear Receptor NUR775.435Citations (PDF)
115Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells
Blood, 2012, 120, 682-690
4.860Citations (PDF)
116Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice7.5142Citations (PDF)
117Induction and molecular signature of pathogenic TH17 cells
Nature Immunology, 2012, 13, 991-999
23.51,123Citations (PDF)
118Emerging new roles of Th17 cells
European Journal of Immunology, 2012, 42, 2211-2214
3.137Citations (PDF)
119Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion
Nature Medicine, 2012, 18, 1394-1400
33.0383Citations (PDF)
120Aiolos promotes TH17 differentiation by directly silencing Il2 expression
Nature Immunology, 2012, 13, 770-777
23.5250Citations (PDF)
121IL-12 family cytokines: immunological playmakers
Nature Immunology, 2012, 13, 722-728
23.51,219Citations (PDF)
122Immune checkpoints in central nervous system autoimmunity
Immunological Reviews, 2012, 248, 122-139
6.498Citations (PDF)
123Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs
Journal of Clinical Investigation, 2012, 122, 2395-2404
10.6132Citations (PDF)
124A Model for How Signal Duration Can Determine Distinct Outcomes of Gene Transcription Programs
PLoS ONE, 2012, 7, e33018
2.36Citations (PDF)
125Control of TH17 cells occurs in the small intestine
Nature, 2011, 475, 514-518
37.9625Citations (PDF)
126The many faces of Th17 cells5.2231Citations (PDF)
127Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation
Immunity, 2011, 35, 986-996
22.6485Citations (PDF)
128Emerging Tim-3 functions in antimicrobial and tumor immunity
Trends in Immunology, 2011, 32, 345-349
10.4242Citations (PDF)
129Type 1 regulatory T cells (Tr1) in autoimmunity
Seminars in Immunology, 2011, 23, 202-208
6.7156Citations (PDF)
130Induction of regulatory Tr1 cells and inhibition of TH17 cells by IL-27
Seminars in Immunology, 2011, 23, 438-445
6.7154Citations (PDF)
131Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
Blood, 2011, 117, 4501-4510
4.8650Citations (PDF)
132T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses7.595Citations (PDF)
133Phosphotyrosine-Dependent Coupling of Tim-3 to T-Cell Receptor Signaling Pathways
Molecular and Cellular Biology, 2011, 31, 3963-3974
2.5266Citations (PDF)
134Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice
Journal of Clinical Investigation, 2011, 121, 4303-4310
10.646Citations (PDF)
135Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
Journal of Experimental Medicine, 2010, 207, 2187-2194
9.31,994Citations (PDF)
136γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism
Immunity, 2010, 33, 351-363
22.6267Citations (PDF)
137T‐bet, a Th1 transcription factor regulates the expression of Tim‐33.1109Citations (PDF)
138The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
Nature Immunology, 2010, 11, 854-861
23.5720Citations (PDF)
139Proinflammatory T helper type 17 cells are effective B-cell helpers7.5507Citations (PDF)
140Tim3 binding to galectin-9 stimulates antimicrobial immunity
Journal of Experimental Medicine, 2010, 207, 2343-2354
9.3195Citations (PDF)
141Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection7.5829Citations (PDF)
142T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice7.5174Citations (PDF)
143Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients
Journal of Experimental Medicine, 2010, 207, 2175-2186
9.31,268Citations (PDF)
144Molecular Pathways in the Induction of Interleukin-27-Driven Regulatory Type 1 Cells1.757Citations (PDF)
145T-bet represses TH17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt
Nature Immunology, 2010, 12, 96-104
23.5367Citations (PDF)
146Th17 cells: from precursors to players in inflammation and infection
International Immunology, 2009, 21, 489-498
3.1219Citations (PDF)
147TIM‐3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
European Journal of Immunology, 2009, 39, 2492-2501
3.1315Citations (PDF)
148High Ro52 Expression in Spontaneous and UV-Induced Cutaneous Inflammation2.367Citations (PDF)
149The costimulatory role of TIM molecules
Immunological Reviews, 2009, 229, 259-270
6.4212Citations (PDF)
150Interleukin-17 and Type 17 Helper T Cells34.51,351Citations (PDF)
151IL-17 and Th17 Cells
Annual Review of Immunology, 2009, 27, 485-517
29.44,654Citations (PDF)
152PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
Journal of Experimental Medicine, 2009, 206, 3015-3029
9.31,949Citations (PDF)
153Interplay Between Effector Th17 and Regulatory T Cells3.1113Citations (PDF)
154IL-21 and TGF-β are required for differentiation of human TH17 cells
Nature, 2008, 454, 350-352
37.9893Citations (PDF)
155Induction and effector functions of TH17 cells
Nature, 2008, 453, 1051-1057
37.91,150Citations (PDF)
156IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells
Nature Immunology, 2008, 9, 1347-1355
23.51,067Citations (PDF)
157New roles for TIM family members in immune regulation
Nature Reviews Immunology, 2008, 8, 577-580
53.8130Citations (PDF)
158Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
Clinical Immunology, 2008, 127, 78-88
2.6455Citations (PDF)
159QS379. Injury Activates and Expands Regulatory T Cells1.60Citations (PDF)
160Role of Th1 and Th17 cells in organ-specific autoimmunity
Journal of Autoimmunity, 2008, 31, 252-256
6.6419Citations (PDF)
161TGF-β signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis7.5107Citations (PDF)
162Galectin-9 Increases Tim-3+ Dendritic Cells and CD8+ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions
Journal of Immunology, 2008, 181, 7660-7669
0.6204Citations (PDF)
163The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
Nature Immunology, 2008, 10, 167-175
23.5687Citations (PDF)
164Immunostimulatory Tim-1–specific antibody deprograms Tregs and prevents transplant tolerance in mice10.6116Citations (PDF)
165Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
Journal of Experimental Medicine, 2007, 204, 1691-1702
9.3124Citations (PDF)
166Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background
International Immunology, 2007, 19, 1235-1248
3.110Citations (PDF)
167Regulation of T-Cell Immunity by T-Cell Immunoglobulin and Mucin Domain Proteins
Transplantation, 2007, 84, S12-S16
2.18Citations (PDF)
168Th17 cells: Effector T cells with inflammatory properties
Seminars in Immunology, 2007, 19, 362-371
6.7397Citations (PDF)
169Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts
Arthritis and Rheumatism, 2007, 56, 3968-3976
6.1103Citations (PDF)
170Th17: the third member of the effector T cell trilogy5.2575Citations (PDF)
171A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells
Nature Immunology, 2007, 8, 1380-1389
23.5777Citations (PDF)
172Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
Nature Medicine, 2007, 13, 423-431
33.0782Citations (PDF)
173IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
Nature, 2007, 448, 484-487
37.91,729Citations (PDF)
174Interferon-α Induces Up-regulation and Nuclear Translocation of the Ro52 Autoantigen as Detected by a Panel of Novel Ro52-specific Monoclonal Antibodies3.1113Citations (PDF)
175Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Nature, 2006, 441, 235-238
37.96,758Citations (PDF)
176Recovery from experimental allergic encephalomyelitis is TGF-β dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells
International Immunology, 2006, 18, 495-503
3.184Citations (PDF)
177TIM Family of Genes in Immunity and Tolerance
Advances in Immunology, 2006, , 227-249
6.696Citations (PDF)
178Myelin oligodendrocyte glycoprotein–specific T and B cells cooperate to induce a Devic-like disease in mice
Journal of Clinical Investigation, 2006, 116, 2393-2402
10.6306Citations (PDF)
179TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation
Nature Immunology, 2005, 6, 455-464
23.5337Citations (PDF)
180The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Nature Immunology, 2005, 6, 1245-1252
23.51,961Citations (PDF)
181Structural Organization and Zn2+-dependent Subdomain Interactions Involving Autoantigenic Epitopes in the Ring-B-box-Coiled-coil (RBCC) Region of Ro52
Journal of Biological Chemistry, 2005, 280, 33250-33261
2.223Citations (PDF)
182Tim-2 regulates T helper type 2 responses and autoimmunity9.3125Citations (PDF)
183The TIM gene family regulates autoimmune and allergic diseases
Trends in Molecular Medicine, 2005, 11, 362-369
7.4208Citations (PDF)
184Myelin proteolipid protein-specific CD4+CD25+ regulatory cells mediate genetic resistance to experimental autoimmune encephalomyelitis7.5178Citations (PDF)
185A chimeric T cell receptor with super-signaling properties
International Immunology, 2004, 16, 889-894
3.114Citations (PDF)
186Loss of T-bet, But Not STAT1, Prevents the Development of Experimental Autoimmune Encephalomyelitis9.3439Citations (PDF)
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