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401 papers • 71,180 citations • Sorted by year • Download PDF (PDF by citations)
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1The transition from genomics to phenomics in personalized population health
Nature Reviews Genetics, 2024, 25, 286-302
19.19Citations (PDF)
2Timing of selective serotonin reuptake inhibitor use and risk for preterm birth and related adverse events: with a consideration of the COVID-19 pandemic period1.83Citations (PDF)
3A Proactive Intervention Study in Metabolic Syndrome High-Risk Populations Using Phenome-Based Actionable P4 Medicine Strategy
Phenomics, 2024, 4, 91-108
5.51Citations (PDF)
4The transition from genomics to phenomics in personalized population health
Nature Reviews Genetics, 2023, 25, 286-302
19.19Citations (PDF)
5Multiple early factors anticipate post-acute COVID-19 sequelae
Cell, 2022, 185, 881-895.e20
35.1679Citations (PDF)
6The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study
The Lancet Digital Health, 2022, 4, e95-e104
16.687Citations (PDF)
7Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness0.01Citations (PDF)
8Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90
Scientific Reports, 2022, 12,
3.712Citations (PDF)
9Heterogeneity in statin responses explained by variation in the human gut microbiome
Med, 2022, 3, 388-405.e6
7.130Citations (PDF)
10Gut microbiome pattern reflects healthy ageing and predicts survival in humans
Nature Metabolism, 2021, 3, 274-286
11.9357Citations (PDF)
11iNetModels 2.0: an interactive visualization and database of multi-omics data
Nucleic Acids Research, 2021, 49, W271-W276
16.228Citations (PDF)
12Utilization of machine learning for identifying symptom severity military-related PTSD subtypes and their biological correlates5.716Citations (PDF)
13One stone, two birds: how a WGS-enabled diagnostic journey transforms into a precision population health service for the 21st century0.90Citations (PDF)
14The geometry of clinical labs and wellness states from deeply phenotyped humans14.115Citations (PDF)
15Serum brain-derived neurotrophic factor remains elevated after long term follow-up of combat veterans with chronic post-traumatic stress disorder
Psychoneuroendocrinology, 2021, 134, 105360
2.510Citations (PDF)
16Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
MSystems, 2021, 6,
4.619Citations (PDF)
17Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19
Nature Biotechnology, 2021, 40, 110-120
18.173Citations (PDF)
18Mouse Organ-Specific Proteins and Functions
Cells, 2021, 10, 3449
4.82Citations (PDF)
19Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease
Journal of Proteome Research, 2020, 19, 346-359
3.714Citations (PDF)
20Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types
Cell Reports, 2020, 32, 108029
6.425Citations (PDF)
21Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19
Cell, 2020, 183, 1479-1495.e20
35.1408Citations (PDF)
22Multiomic blood correlates of genetic risk identify presymptomatic disease alterations7.723Citations (PDF)
23Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males
Molecular Psychiatry, 2020, 26, 4300-4314
8.327Citations (PDF)
24A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD
Molecular Psychiatry, 2020, 26, 4999-5009
8.361Citations (PDF)
25Epigenetic Biotypes of PTSD in War-Zone Exposed Veteran and Active Duty Males
Biological Psychiatry, 2020, 87, S8-S9
1.72Citations (PDF)
26Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome7.742Citations (PDF)
27Core transcriptional regulatory circuits in prion diseases
Molecular Brain, 2020, 13,
3.28Citations (PDF)
28Deep phenotyping during pregnancy for predictive and preventive medicine13.120Citations (PDF)
29Effect of Combat Exposure and Posttraumatic Stress Disorder on Telomere Length and Amygdala Volume1.310Citations (PDF)
30Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis
Scientific Reports, 2020, 10,
3.712Citations (PDF)
31Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity3.026Citations (PDF)
32Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder2.621Citations (PDF)
33Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals3.651Citations (PDF)
34Blood metabolome predicts gut microbiome α-diversity in humans
Nature Biotechnology, 2019, 37, 1217-1228
18.1221Citations (PDF)
35Blood Is a Window into Health and Disease
Clinical Chemistry, 2019, 65, 1204-1206
1.116Citations (PDF)
36Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program3.739Citations (PDF)
37Genomic and molecular characterization of preterm birth7.753Citations (PDF)
38Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders
Cell Systems, 2019, 8, 122-135.e7
6.032Citations (PDF)
39MULTI-OMIC BIOLOGICAL AGE ESTIMATION, CORRELATION WITH WELLNESS, DISEASE PHENOTYPES: LONGITUDINAL SAMPLE OF 3558
Innovation in Aging, 2019, 3, S209-S209
0.10Citations (PDF)
40Personalized, Precision, and N-of-One Medicine: A Clarification of Terminology and Concepts0.621Citations (PDF)
41A Blueprint for Systems Biology
Clinical Chemistry, 2019, 65, 342-344
1.17Citations (PDF)
42Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder0.99Citations (PDF)
43A systems approach to clinical oncology uses deep phenotyping to deliver personalized care25.344Citations (PDF)
44Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder
Molecular Psychiatry, 2019, 25, 3337-3349
8.371Citations (PDF)
45Human Gut Microbiota and Gastrointestinal Cancer6.1298Citations (PDF)
46Extracellular vesicle <scp>RNA</scp>s reflect placenta dysfunction and are a biomarker source for preterm labour4.161Citations (PDF)
47Lessons Learned as President of the Institute for Systems Biology (2000–2018)6.15Citations (PDF)
48The building blocks of successful translation of proteomics to the clinic7.627Citations (PDF)
49Whole genome sequence and comparative analysis of Borrelia burgdorferi MM1
PLoS ONE, 2018, 13, e0198135
2.510Citations (PDF)
50Reply to "Precision medicine in the clouds"
Nature Biotechnology, 2018, 36, 680-682
18.11Citations (PDF)
51Population-specific genetic modification of Huntington's disease in Venezuela
PLoS Genetics, 2018, 14, e1007274
3.323Citations (PDF)
52Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cells7.769Citations (PDF)
53A Cell-Surface Membrane Protein Signature for Glioblastoma
Cell Systems, 2017, 4, 516-529.e7
6.036Citations (PDF)
54Genome-Scale Transcriptional Regulatory Network Models of Psychiatric Disorders0.91Citations (PDF)
55Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration &amp; Cancer3.791Citations (PDF)
56A wellness study of 108 individuals using personal, dense, dynamic data clouds
Nature Biotechnology, 2017, 35, 747-756
18.1309Citations (PDF)
57Beyond cancer genes: colorectal cancer as robust intrinsic states formed by molecular interactions
Open Biology, 2017, 7, 170169
3.412Citations (PDF)
58Viva Europa, a Land of Excellence in Research and Innovation for Health and Wellbeing3.06Citations (PDF)
59The P4 Health Spectrum – A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan5.9186Citations (PDF)
60The P4 Health Spectrum – A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan3.08Citations (PDF)
61Evolutionary history of Tibetans inferred from whole-genome sequencing
PLoS Genetics, 2017, 13, e1006675
3.380Citations (PDF)
62Welcome to Progress in Preventive Medicine from the Editorial Board3.00Citations (PDF)
63Predictive Big Data Analytics: A Study of Parkinson’s Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations
PLoS ONE, 2016, 11, e0157077
2.5102Citations (PDF)
64New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections3.737Citations (PDF)
65Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients
Journal of Proteome Research, 2016, 15, 3724-3740
3.726Citations (PDF)
66Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals2.613Citations (PDF)
67TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme
Stem Cells, 2016, 34, 2276-2289
3.341Citations (PDF)
68Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human Proteome
Cell, 2016, 166, 766-778
35.1261Citations (PDF)
69Opening a SWATH Window on Posttranslational Modifications: Automated Pursuit of Modified Peptides4.836Citations (PDF)
70A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD5114.1120Citations (PDF)
71Endogenous molecular-cellular hierarchical modeling of prostate carcinogenesis uncovers robust structure4.222Citations (PDF)
72Integrating big data and actionable health coaching to optimize wellness
BMC Medicine, 2015, 13, 4
7.464Citations (PDF)
73Microarray Based Screening of Peptide Nano Probes for HER2 Positive Tumor
Analytical Chemistry, 2015, 87, 8367-8372
6.748Citations (PDF)
74Big biomedical data as the key resource for discovery science4.166Citations (PDF)
75Identification of copy number variants in whole-genome data using Reference Coverage Profiles2.417Citations (PDF)
76Automated Validation of Results and Removal of Fragment Ion Interferences in Targeted Analysis of Data-independent Acquisition Mass Spectrometry (MS) using SWATHProphet4.832Citations (PDF)
77Rare variants in neuronal excitability genes influence risk for bipolar disorder7.7136Citations (PDF)
78Developmental biologist Eric H. Davidson, 1937–20157.70Citations (PDF)
79Sequence-Level Analysis of the Major European Huntington Disease Haplotype6.819Citations (PDF)
80A Gain-of-Function Mutation in TRPV3 Causes Focal Palmoplantar Keratoderma in a Chinese Family0.728Citations (PDF)
81Global analysis of H3K4me3 and H3K27me3 profiles in glioblastoma stem cells and identification of SLC17A7 as a bivalent tumor suppressor gene
Oncotarget, 2015, 6, 5369-5381
1.761Citations (PDF)
82Whole-Genome Sequencing of the World’s Oldest People
PLoS ONE, 2014, 9, e112430
2.556Citations (PDF)
83Quantitative Liver-Specific Protein Fingerprint in Blood: A Signature for Hepatotoxicity
Theranostics, 2014, 4, 215-228
11.445Citations (PDF)
84Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder7.738Citations (PDF)
85Relationship Estimation from Whole-Genome Sequence Data
PLoS Genetics, 2014, 10, e1004144
3.355Citations (PDF)
86Realistic artificial DNA sequences as negative controls for computational genomics
Nucleic Acids Research, 2014, 42, e99-e99
16.223Citations (PDF)
87Rapid Screening of Peptide Probes through <i>In Situ</i> Single-Bead Sequencing Microarray
Analytical Chemistry, 2014, 86, 11854-11859
6.742Citations (PDF)
88Demystifying Disease, Democratizing Health Care13.163Citations (PDF)
89Protein-Centric N-Glycoproteomics Analysis of Membrane and Plasma Membrane Proteins
Journal of Proteome Research, 2014, 13, 2705-2714
3.724Citations (PDF)
90A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data
Nature Biotechnology, 2014, 32, 663-669
18.180Citations (PDF)
91Origin of the <i>PSEN1</i> E280A mutation causing early‐onset Alzheimer's disease0.740Citations (PDF)
92Systems Approach to Neurodegenerative Disease Biomarker Discovery12.442Citations (PDF)
93Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes
Nature Genetics, 2014, 46, 1327-1332
16.3168Citations (PDF)
94Label-Free Quantitative Detection of Tumor-Derived Exosomes through Surface Plasmon Resonance Imaging
Analytical Chemistry, 2014, 86, 8857-8864
6.7221Citations (PDF)
95Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury
Biomarkers, 2014, 19, 578-584
2.03Citations (PDF)
96An Epigenetic Biomarker Panel for Glioblastoma Multiforme Personalized Medicine through DNA Methylation Analysis of Human Embryonic Stem Cell-like Signature1.920Citations (PDF)
97P4 Medicine Needs P4 Education
Current Pharmaceutical Design, 2014, 20, 6071-6072
2.333Citations (PDF)
98From Phage lambda to human cancer: endogenous molecular‐cellular network hypothesis
Quantitative Biology, 2013, 1, 32-49
1.125Citations (PDF)
99An automated Teflon microfluidic peptide synthesizer
Lab on A Chip, 2013, 13, 3347
5.622Citations (PDF)
100Functional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology
2013, , 3-41
5Citations (PDF)
101Every Life Has Equal Value
Cell, 2013, 154, 1178-1179
35.12Citations (PDF)
102A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules13.1155Citations (PDF)
103Participatory medicine: a driving force for revolutionizing healthcare
Genome Medicine, 2013, 5, 110
9.9126Citations (PDF)
104Systems Biology and Systems Medicine
2013, , 60-72
2Citations (PDF)
105The human genome project: big science transforms biology and medicine
Genome Medicine, 2013, 5, 79
9.9199Citations (PDF)
106Systems Medicine and the Emergence of Proactive P4 Medicine
2013, , 445-467
2Citations (PDF)
107Glycocapture-Assisted Global Quantitative Proteomics (gagQP) Reveals Multiorgan Responses in Serum Toxicoproteome
Journal of Proteome Research, 2013, 12, 2034-2044
3.715Citations (PDF)
108P4 Medicine: How Systems Medicine Will Transform the Healthcare Sector and Society
Personalized Medicine, 2013, 10, 565-576
1.4421Citations (PDF)
109Interview with Leroy Hood
Bioanalysis, 2013, 5, 1475-1478
1.20Citations (PDF)
110Multi-study Integration of Brain Cancer Transcriptomes Reveals Organ-Level Molecular Signatures
PLoS Computational Biology, 2013, 9, e1003148
3.313Citations (PDF)
111Evolutionary etiology of high-grade astrocytomas7.735Citations (PDF)
112Systems Biology and P4 Medicine: Past, Present, and Future1.1201Citations (PDF)
113Cell type-specific genes show striking and distinct patterns of spatial expression in the mouse brain7.759Citations (PDF)
114A Review of Computational Tools in microRNA Discovery2.479Citations (PDF)
115Optimal Scaling of Digital Transcriptomes
PLoS ONE, 2013, 8, e77885
2.522Citations (PDF)
116N-Glycoproteome of E14.Tg2a Mouse Embryonic Stem Cells
PLoS ONE, 2013, 8, e55722
2.517Citations (PDF)
117Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells7.7275Citations (PDF)
118Editorial: Systems biology and personalized medicine – the future is now
Biotechnology Journal, 2012, 7, 938-939
3.427Citations (PDF)
119Systems Approaches to Biology and Disease Enable Translational Systems Medicine6.167Citations (PDF)
120A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory
New Biotechnology, 2012, 29, 613-624
5.2436Citations (PDF)
121A Systems Approach to Rheumatoid Arthritis
PLoS ONE, 2012, 7, e51508
2.524Citations (PDF)
122<scp>SRM</scp> targeted proteomics in search for biomarkers of <scp>HCV</scp>‐induced progression of fibrosis to cirrhosis in <scp>HALT</scp>‐<scp>C</scp> patients
Proteomics, 2012, 12, 1244-1252
3.832Citations (PDF)
123Tackling the Microbiome
Science, 2012, 336, 1209-1209
38.242Citations (PDF)
124Revolutionizing medicine in the 21<sup>st</sup> century through systems approaches
Biotechnology Journal, 2012, 7, 992-1001
3.4194Citations (PDF)
125Systems medicine and integrated care to combat chronic noncommunicable diseases
Genome Medicine, 2011, 3, 43
9.9164Citations (PDF)
126Predictive, personalized, preventive, participatory (P4) cancer medicine25.3627Citations (PDF)
127Boosting Signal-to-Noise in Complex Biology: Prior Knowledge Is Power
Cell, 2011, 144, 860-863
35.1148Citations (PDF)
128Chromosomal Haplotypes by Genetic Phasing of Human Families6.849Citations (PDF)
129Landscape of the SOX2 protein–protein interactome
Proteomics, 2011, 11, 921-934
3.859Citations (PDF)
130Principal network analysis: identification of subnetworks representing major dynamics using gene expression data
Bioinformatics, 2011, 27, 391-398
5.043Citations (PDF)
131Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation
PLoS Pathogens, 2011, 7, e1002391
4.533Citations (PDF)
132The Hallmarks of Cancer Revisited Through Systems Biology and Network Modelling
2011, , 245-266
2Citations (PDF)
133Analysis of chemotherapy response programs in ovarian cancers by the next-generation sequencing technologies
Gynecologic Oncology, 2010, 117, 159-169
1.656Citations (PDF)
134Systems Biology and the Discovery of Diagnostic Biomarkers
Disease Markers, 2010, 28, 199-207
1.752Citations (PDF)
135Massively Parallel Signature Sequencing and Bioinformatics Analysis Identifies Up-Regulation of TGFBI and SOX4 in Human Glioblastoma
PLoS ONE, 2010, 5, e10210
2.575Citations (PDF)
136Bioprocessing of Human Glioblastoma Brain Cancer Tissue
Tissue Engineering - Part A, 2010, 16, 1169-1177
2.812Citations (PDF)
137Identifying Tightly Regulated and Variably Expressed Networks by Differential Rank Conservation (DIRAC)
PLoS Computational Biology, 2010, 6, e1000792
3.364Citations (PDF)
138Epigenetic Regulation of Wnt Pathway Antagonists in Human Glioblastoma Multiforme
Genes and Cancer, 2010, 1, 81-90
3.842Citations (PDF)
139Parallel microfluidic surface plasmon resonance imaging arrays
Lab on A Chip, 2010, 10, 581
5.6116Citations (PDF)
140Systems Biology and Systems Medicine
2010, , 131-141
3Citations (PDF)
141Predictive, preventive, personalized and participatory medicine: back to the future
Genome Medicine, 2010, 2, 57
9.9134Citations (PDF)
142Systems approaches to biology and disease: integrating discovery and hypothesis‐driven paradigms
FASEB Journal, 2010, 24,
0.70Citations (PDF)
143Systems Biology and the Emergence of Systems Medicine
2009, , 74-85
5Citations (PDF)
144Quantitative Proteomics Analysis Integrated with Microarray Data Reveals That Extracellular Matrix Proteins, Catenins, and P53 Binding Protein 1 Are Important for Chemotherapy Response in Ovarian Cancers1.971Citations (PDF)
145Dysregulated gene expression networks in human acute myelogenous leukemia stem cells7.7233Citations (PDF)
146The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases3.018Citations (PDF)
147Detailed transcriptome atlas of the pancreatic beta cell1.893Citations (PDF)
148Elevated expression of DKK1 is associated with cytoplasmic/nuclear β-catenin accumulation and poor prognosis in hepatocellular carcinomas
Journal of Hepatology, 2009, 50, 948-957
2.9122Citations (PDF)
149Systems medicine: the future of medical genomics and healthcare
Genome Medicine, 2009, 1, 2
9.9311Citations (PDF)
150Integrated Expression Profiling and ChIP-seq Analyses of the Growth Inhibition Response Program of the Androgen Receptor
PLoS ONE, 2009, 4, e6589
2.570Citations (PDF)
151Targeting Stem Cells-Clinical Implications for Cancer Therapy1.847Citations (PDF)
152Systems biology and cancer stem cells4.123Citations (PDF)
153Proteomics cataloging analysis of human expressed prostatic secretions reveals rich source of biomarker candidates2.321Citations (PDF)
154Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood
Nature Biotechnology, 2008, 26, 1373-1378
18.1481Citations (PDF)
155Direct multiplexed measurement of gene expression with color-coded probe pairs
Nature Biotechnology, 2008, 26, 317-325
18.11,690Citations (PDF)
156Cancer as robust intrinsic state of endogenous molecular-cellular network shaped by evolution
Medical Hypotheses, 2008, 70, 678-684
0.7123Citations (PDF)
157WDR19 Expression is Increased in Prostate Cancer Compared with Normal Cells, but Low-Intensity Expression in Cancers is Associated with Shorter Time to Biochemical Failures and Local Recurrence
Clinical Cancer Research, 2008, 14, 1397-1406
6.415Citations (PDF)
158Quantitative Serum Proteomics from Surface Plasmon Resonance Imaging4.860Citations (PDF)
159Systems biology at the Institute for Systems Biology4.358Citations (PDF)
160Gene regulatory networks and embryonic specification7.77Citations (PDF)
161“Systems biology and systems medicine: From reactive to predictive, personalized, preventive and participatory (P4) medicine”
2008, ,
4Citations (PDF)
162A Systems Approach to Medicine Will Transform Healthcare
2008, , 337-366
9Citations (PDF)
163Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas7.7133Citations (PDF)
164Shotgun Glycopeptide Capture Approach Coupled with Mass Spectrometry for Comprehensive Glycoproteomics4.8141Citations (PDF)
165Increased Expression of SIM2-s Protein Is a Novel Marker of Aggressive Prostate Cancer
Clinical Cancer Research, 2007, 13, 892-897
6.447Citations (PDF)
166Proteomics Analysis of the Interactome of N-myc Downstream Regulated Gene 1 and Its Interactions with the Androgen Response Program in Prostate Cancer Cells4.875Citations (PDF)
167Molecular profiling of stem cells
Clinica Chimica Acta, 2007, 378, 24-32
1.217Citations (PDF)
168A Predictive Model for Transcriptional Control of Physiology in a Free Living Cell
Cell, 2007, 131, 1354-1365
35.1251Citations (PDF)
169Suggestive genetic linkage to chromosome 11p11.2-q12.2 in hereditary prostate cancer families with primary kidney cancer
Prostate, 2007, 67, 732-742
2.213Citations (PDF)
170PTEN-deficient intestinal stem cells initiate intestinal polyposis
Nature Genetics, 2007, 39, 189-198
16.3375Citations (PDF)
171Efficiency, Robustness, and Stochasticity of Gene Regulatory Networks in Systems Biology: λ Switch as a Working Example
2007, , 336-371
6Citations (PDF)
172Title is missing!
Genome Biology, 2006, 7, R36
14.0388Citations (PDF)
173Genetic Mapping at 3-Kilobase Resolution Reveals Inositol 1,4,5-Triphosphate Receptor 3 as a Risk Factor for Type 1 Diabetes in Sweden6.852Citations (PDF)
174Proteins Associated with Cisplatin Resistance in Ovarian Cancer Cells Identified by Quantitative Proteomic Technology and Integrated with mRNA Expression Levels4.8110Citations (PDF)
175KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells
Prostate, 2006, 66, 936-944
2.230Citations (PDF)
176Analysis of the DNA sequence and duplication history of human chromosome 15
Nature, 2006, 440, 671-675
40.161Citations (PDF)
177Health Care of the 21st Century: Predictive, Preventive, Personalized and Participatory (P4) Medicine1.52Citations (PDF)
178A Third Approach to Gene Prediction Suggests Thousands of Additional Human Transcribed Regions3.336Citations (PDF)
179Genome-Wide Analysis of Epigenetic Silencing Identifies BEX1 and BEX2 as Candidate Tumor Suppressor Genes in Malignant Glioma
Cancer Research, 2006, 66, 6665-6674
0.6124Citations (PDF)
180Long-range multilocus haplotype phasing of the MHC7.735Citations (PDF)
181A molecular correlate to the Gleason grading system for prostate adenocarcinoma7.7232Citations (PDF)
182A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Nature Immunology, 2005, 6, 1133-1141
13.13,622Citations (PDF)
183Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry
Nature Methods, 2005, 2, 591-598
14.5263Citations (PDF)
184Evidence for the Presence of Disease-Perturbed Networks in Prostate Cancer Cells by Genomic and Proteomic Analyses: A Systems Approach to Disease
Cancer Research, 2005, 65, 3081-3091
0.689Citations (PDF)
185Interchromosomal Segmental Duplications Explain the Unusual Structure of PRSS3, the Gene for an Inhibitor-Resistant Trypsinogen
Molecular Biology and Evolution, 2005, 22, 1712-1720
4.726Citations (PDF)
186A data integration methodology for systems biology7.7267Citations (PDF)
187A Combined Genomewide Linkage Scan of 1,233 Families for Prostate Cancer–Susceptibility Genes Conducted by the International Consortium for Prostate Cancer Genetics6.8127Citations (PDF)
188Proteomic analysis identifies that 14-3-3  interacts with  -catenin and facilitates its activation by Akt7.7128Citations (PDF)
189Systems Level Insights Into the Stress Response to UV Radiation in the Halophilic Archaeon Halobacterium NRC-1
Genome Research, 2004, 14, 1025-1035
4.6118Citations (PDF)
190Identification of a prostate cancer susceptibility locus on chromosome 7q11–21 in Jewish families7.721Citations (PDF)
191Genome sequence of Haloarcula marismortui: A halophilic archaeon from the Dead Sea
Genome Research, 2004, 14, 2221-2234
4.6256Citations (PDF)
192The impact of systems approaches on biological problems in drug discovery
Nature Biotechnology, 2004, 22, 1215-1217
18.1188Citations (PDF)
193Electrochemically Programmed, Spatially Selective Biofunctionalization of Silicon Wires
Langmuir, 2004, 20, 10630-10638
3.899Citations (PDF)
194Title is missing!
Genome Biology, 2004, 5, R52
14.038Citations (PDF)
195Systems Biology, Proteomics, and the Future of Health Care:  Toward Predictive, Preventative, and Personalized Medicine3.7626Citations (PDF)
196Systems Biology Experimental Design - Considerations for Building Predictive Gene Regulatory Network Models for Prokaryotic Systems
Current Genomics, 2004, 5, 527-544
1.216Citations (PDF)
197Initial Proteome Analysis of Model Microorganism<i>Haemophilus influenzae</i>Strain Rd KW20
Journal of Bacteriology, 2003, 185, 4593-4602
3.061Citations (PDF)
198Leroy Hood expounds the principles, practice and future of systems biology
Drug Discovery Today, 2003, 8, 436-438
7.233Citations (PDF)
199Systems biology: integrating technology, biology, and computation4.6211Citations (PDF)
200Proteomic analysis of human prostasomes
Prostate, 2003, 56, 150-161
2.2208Citations (PDF)
201Genomic scan of 254 hereditary prostate cancer families
Prostate, 2003, 57, 309-319
2.256Citations (PDF)
202The DNA sequence and analysis of human chromosome 14
Nature, 2003, 421, 601-607
40.191Citations (PDF)
203The digital code of DNA
Nature, 2003, 421, 444-448
40.1206Citations (PDF)
204Proteomic Analysis of an Extreme Halophilic Archaeon, Halobacterium sp. NRC-14.850Citations (PDF)
205From functional genomics to systems biology: concepts and practices
Comptes Rendus - Biologies, 2003, 326, 879-892
0.597Citations (PDF)
206Isolation and characterization of human and mouse WDR19,a novel WD-repeat protein exhibiting androgen-regulated expression in prostate epithelium☆
Genomics, 2003, 82, 331-342
2.713Citations (PDF)
207Analysis of the Gene-Dense Major Histocompatibility Complex Class III Region and Its Comparison to Mouse
Genome Research, 2003, 13, 2621-2636
4.685Citations (PDF)
208Hematopoietic Stem Cells Contribute to the Regeneration of Renal Tubules after Renal Ischemia-Reperfusion Injury in Mice0.4352Citations (PDF)
209Regulatory gene networks and the properties of the developmental process7.7186Citations (PDF)
210Predicting Demographic Group Structures Based on DNA Sequence Data
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211Analysis of Acute Myelogenous Leukemia: Preparation of Samples for Genomic and Proteomic Analyses2.136Citations (PDF)
212Complementary Profiling of Gene Expression at the Transcriptome and Proteome Levels in Saccharomyces cerevisiae4.8546Citations (PDF)
213Genetic Effects on Age-Dependent Onset and Islet Cell Autoantibody Markers in Type 1 Diabetes
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216Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion7.760Citations (PDF)
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219Differential gene expression profiling of adult murine hematopoietic stem cells
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222Analysis of the Human Neurexin Genes: Alternative Splicing and the Generation of Protein Diversity
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223A Provisional Regulatory Gene Network for Specification of Endomesoderm in the Sea Urchin Embryo
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224Whole-Genome Shotgun Assembly and Analysis of the Genome of <i>Fugu rubripes</i>
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226Human prostate epithelial cell-type cDNA libraries and prostate expression patterns
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227Substitution Model of Sequence Evolution for the Human Immunodeficiency Virus Type 1 Subtype B gp120 Gene over the C2-V5 Region1.713Citations (PDF)
228Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network
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229A NEWAPPROACH TODECODINGLIFE: Systems Biology7.41,310Citations (PDF)
230Comparative Genomics of the Human and Mouse T Cell Receptor Loci
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231Characterization of the Japanese pufferfish ( Takifugu rubripes ) T-cell receptor α locus reveals a unique genomic organization
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236Understanding the Adaptation of Halobacterium Species NRC-1 to Its Extreme Environment through Computational Analysis of Its Genome Sequence
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238brp and blh Are Required for Synthesis of the Retinal Cofactor of Bacteriorhodopsin in Halobacterium salinarum
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239Rapid Depletion of Peripheral Antigen-Specific T Cells in TCR-Transgenic Mice After Oral Administration of Myelin Basic Protein
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245Modeling the Feasibility of Whole Genome Shotgun Sequencing Using a Pairwise End Strategy
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246A Genomic Scan of Families with Prostate Cancer Identifies Multiple Regions of Interest6.877Citations (PDF)
247GrpL, a Grb2-related Adaptor Protein, Interacts with SLP-76 to Regulate Nuclear Factor of Activated T Cell Activation
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248Activation of the c-Jun N-terminal Kinase/Stress-activated Protein Kinase Pathway by Overexpression of Caspase-8 and Its Homologs
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249Gaps in the Human Genome Project
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262Genetic Evaluation of Suspected Cases of Transient HIV-1 Infection of Infants
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265Evolution of a Simian Immunodeficiency Virus Pathogen
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272Low Fidelity Mutants in the O-Helix of Thermus aquaticus DNA Polymerase I
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286Frequency and Polymorphism of Simple Sequence Repeats in a Contiguous 685-kb DNA Sequence Containing the Human T-Cell Receptor β-Chain Gene Complex
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300Sequence Similarities of Myelin Basic Protein Promoters from Mouse and Shark: Implications for the Control of Gene Expression in Myelinating Cells
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308Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor CαCδ region
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318Further localization of a multiple sclerosis susceptibility gene on chromosome 7q using a new T cell receptor beta-chain DNA polymorphism
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324Phosphorescent zinc sulfide is a nonradioactive alternative for marking autoradiograms
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326Role of Myelin Basic Protein in the Formation of Central Nervous System Myelin4.556Citations (PDF)
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328The myelin proteins of the shark brain are similar to the myelin proteins of the mammalian peripheral nervous system1.780Citations (PDF)
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333Autoimmune T cells: Immune recognition of normal and variant peptide epitopes and peptide-based therapy
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337A novel mutation in myelin-deficient mice results in unstable myelin basic protein gene transcripts
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